CN102688457A - Medicament for treating chronic respiratory disease of chicken and preparation method thereof - Google Patents

Medicament for treating chronic respiratory disease of chicken and preparation method thereof Download PDF

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Publication number
CN102688457A
CN102688457A CN2012102017436A CN201210201743A CN102688457A CN 102688457 A CN102688457 A CN 102688457A CN 2012102017436 A CN2012102017436 A CN 2012102017436A CN 201210201743 A CN201210201743 A CN 201210201743A CN 102688457 A CN102688457 A CN 102688457A
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parts
radix
kilograms
medicine
medicament
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CN2012102017436A
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孟作琴
杨鲜梅
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SHANXI SHUANGYING ANIMAL PHARMACEUTICAL Co Ltd
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SHANXI SHUANGYING ANIMAL PHARMACEUTICAL Co Ltd
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Priority to CN2012102017436A priority Critical patent/CN102688457A/en
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Abstract

The invention discloses a medicament for treating chronic respiratory disease of chicken and a preparation method thereof. The medicament is prepared from the following Chinese herbal medicinal raw materials in parts by mass: 45 to 50 parts of sea-ear shell, 40 to 50 parts of cassia occidentalis, 45 to 50 parts of Chinese atractylode rhizome, 45 to 50 parts of platycodon grandiflorum, 30 to 40 parts of Chinese rhubarb, 30 to 40 parts of baical skullcap root, 30 to 40 parts of dried tangerine peel, 30 to 40 parts of lightyellow sophora root, 30 to 40 parts of liquorice, 30 to 40 parts of cape jasmine, 30 to 40 parts of turmeric root-tuber, 90 to 100 parts of houttuynia cordata, and 50 to 65 parts of perilla leaf. The preparation method comprises the following steps: weighing a certain amount of the Chinese medicinal raw materials in mass parts; and crushing, screening and mixing to prepare the medicinal powder. The medicament for treating chronic respiratory disease of chicken is suitable for lung heat cough, mouth breathing, respiratory rale, anepithymia and other symptoms. Large scale application proves that the medicament has quick response and good curative effect. The medicament is a pure Chinese medicinal preparation, has no residue, toxic or side effect compared with the western medicaments.

Description

Treatment chicken chronic respiratory tract disease medicine and preparation method thereof
Technical field
The present invention relates to use the treatment by Chinese herbs poultry respiratory tract diseases, particularly relating to a kind of is the medicine of the treatment chicken chronic respiratory tract disease processed of raw material with the Chinese herbal medicine, the invention still further relates to the method for preparing of this medicine.
Background technology
Chronic respiratory disease is a kind of chronic respiratory infectious disease that is caused by mycoplasma gallisepticum.It is characterized in that cough, sneeze and tracheal rale, cheesy thing is arranged in upper respiratory tract infection and the trachea, adult chicken is inapparent infection.Primary disease is distributed in countries in the world, also is one of important infectious disease of harm poultry husbandry.The chicken chronic respiratory tract disease can cause that growth of meat chicken speed significantly reduces, feedstuff-meat ratio obviously improves, laying rate of laying hen reduces, abnormal-shape egg increases, the hatching of breeding eggs rate reduces, be good for degradation serious consequence under the young rate.Especially in the growth of meat chicken process, be easy to take place respiratory tract disease, or when immune respiratory tract live-virus vaccine, be very easy to serious vaccine reaction takes place, cause the increase and the production loss of medicine expense.
The chicken chronic respiratory tract disease is the normal property the sent out disease of a type of chicken house; Respiratory tract disease nearly all takes place in the scale chicken house; Its sickness rate is 30%-60%, and mortality rate is 5%-30%, becomes poultry husbandry and veterinary's diagnosis and treatment personnel one of stubborn problem very clinically; And difficult anti-difficult control is given to produce and is caused enormous economic loss.In clinical treatment, because antibiotic life-time service causes endurance strain constantly to increase, seriously influenced therapeutic effect, it is more to add secondary infection clinically again, has more increased the treatment difficulty to the chicken respiratory disease, presses conventional therapy clinically and is difficult to.Use the herbal control fowl disease, in China long history is arranged, so far, it still has important practical significance to the control of fowl disease.In recent years, the broad research to Chinese herbal medicine shows that it not only has effect disease-resistant, enhancing immunity, can also improve efficiency of feed utilization, conversion ratio and growth promotion effect.The Chinese herbal medicine toxic and side effects is little, can not produce drug resistance, the resistance against diseases that stress to regulate allomeric function during application, improves body self, and prolonged application is safe and reliable.
Summary of the invention
The purpose of this invention is to provide a kind of medicine of treating the chicken chronic respiratory tract disease, its curative effect is fast, good effect, and the medicine of non-evident effect, and the present invention also extracts the method for preparing of this medicine.
The medicine of chicken chronic respiratory tract disease of the present invention is made up of the raw material of Chinese medicine medicine of following mass parts: Concha Haliotidis 45 ~ 50, Semen Cassiae 40 ~ 50, Rhizoma Atractylodis 45 ~ 50, Radix Platycodonis 45 ~ 50, Radix Et Rhizoma Rhei 30 ~ 40, Radix Scutellariae 30 ~ 40, Pericarpium Citri Reticulatae 30 ~ 40, Radix Sophorae Flavescentis 30 ~ 40, Radix Glycyrrhizae 30 ~ 40, Fructus Gardeniae 30 ~ 40, Radix Curcumae 30 ~ 40, Herba Houttuyniae 90 ~ 100, Folium Perillae 50 ~ 65.
Further, the raw material of Chinese medicine medicine of the preferred following mass parts of medicine of chicken chronic respiratory tract disease of the present invention is formed: Concha Haliotidis 50, Semen Cassiae 50, Rhizoma Atractylodis 50, Radix Platycodonis 50, Radix Et Rhizoma Rhei 40, Radix Scutellariae 40, Pericarpium Citri Reticulatae 40, Radix Sophorae Flavescentis 40, Radix Glycyrrhizae 40, Fructus Gardeniae 35, Radix Curcumae 35, Herba Houttuyniae 100, Folium Perillae 60.
In the said medicine prescription, Concha Haliotidis, Semen Cassiae liver heat removing and eyesight improving; The Fructus Gardeniae clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body; Radix Et Rhizoma Rhei, the detumescence of Radix Curcumae blood activating and trace dispersing; The Herba Houttuyniae heat-clearing and toxic substances removing is controlled lung abscess nose pus; Folium Perillae, Radix Glycyrrhizae are induced sweat and reduce phlegm, relieving cough and asthma; Radix Sophorae Flavescentis, Rhizoma Atractylodis, heat clearing and damp drying, strengthening the spleen to promote digestion; Spleen invigorating during Pericarpium Citri Reticulatae is regulated the flow of vital energy and transferred; The Radix Platycodonis medicine carrying is up, clearing throat.Full side has clearing away heat,cooling blood and removing toxin, relieving cough and asthma, the effect that suppressing the hyperactive liver makes eye bright.
For the stability and convenient clinical use that improves product, said medicine is processed the powder on the pharmaceutics.
The method for preparing of drug powder of the present invention is following:
Take by weighing a certain amount of each raw material of Chinese medicine by above-mentioned mass parts, be powder through pulverizing, sieve, mixing.
The method for using of powder of the present invention is: dosage, chick by every adult chicken 5g powder reduce by half, and reconstitute with boiled water, wait temperature and irritate clothes, treat continuously 5 days.
The medicine of chicken chronic respiratory tract disease of the present invention is applicable to the chicken cough due to lung-heat, mouth breathing, and diseases such as respiratory tract rale, inappetence, large-scale application prove that curative effect is fast, good effect.Medicine of the present invention belongs to pure Chinese medicinal preparation, compares no drug residue with Western medicine, has no side effect.
The specific embodiment
Embodiment 1
Get 5 kilograms of Concha Haliotidis, 5 kilograms of Semen Cassiae, 5 kilograms of Rhizoma Atractylodis, 5 kilograms of Radix Platycodoniss; 4 kilograms of Radix Et Rhizoma Rhei, 4 kilograms of Radix Scutellariaes, 4 kilograms of Pericarpium Citri Reticulataes, 4 kilograms of Radix Sophorae Flavescentiss, 4 kilograms in Radix Glycyrrhizae; 3.5 kilograms of Fructus Gardeniaes, 3.5 kilograms of Radix Curcumaes; 10 kilograms of Herba Houttuyniae, 6 kilograms of Folium Perillae are pulverized said medicine, cross 60 mesh sieves, are mixed the drug powder that is the chicken chronic respiratory tract disease.
Embodiment 2
Get 5 kilograms of Concha Haliotidis, 4 kilograms of Semen Cassiae, 5 kilograms of Rhizoma Atractylodis, 4.5 kilograms of Radix Platycodoniss; 4 kilograms of Radix Et Rhizoma Rhei, 3 kilograms of Radix Scutellariaes, 4 kilograms of Pericarpium Citri Reticulataes, 3 kilograms of Radix Sophorae Flavescentiss, 4 kilograms in Radix Glycyrrhizae; 3 kilograms of Fructus Gardeniaes, 4 kilograms of Radix Curcumaes; 9 kilograms of Herba Houttuyniae, 6.5 kilograms of Folium Perillae are pulverized said medicine, cross 60 mesh sieves, are mixed the drug powder that is the chicken chronic respiratory tract disease.
Embodiment 3
Get 4.5 kilograms of Concha Haliotidis, 5 kilograms of Semen Cassiae, 4.5 kilograms of Rhizoma Atractylodis, 5 kilograms of Radix Platycodoniss; 3 kilograms of Radix Et Rhizoma Rhei, 4 kilograms of Radix Scutellariaes, 3 kilograms of Pericarpium Citri Reticulataes, 4 kilograms of Radix Sophorae Flavescentiss, 3 kilograms in Radix Glycyrrhizae; 4 kilograms of Fructus Gardeniaes, 3 kilograms of Radix Curcumaes; 10 kilograms of Herba Houttuyniae, 5 kilograms of Folium Perillae are pulverized said medicine, cross 60 mesh sieves, are mixed the drug powder that is the chicken chronic respiratory tract disease.
Embodiment 4
Get 5 kilograms of Concha Haliotidis, 5 kilograms of Semen Cassiae, 5 kilograms of Rhizoma Atractylodis, 5 kilograms of Radix Platycodoniss; 4 kilograms of Radix Et Rhizoma Rhei, 4 kilograms of Radix Scutellariaes, 4 kilograms of Pericarpium Citri Reticulataes, 4 kilograms of Radix Sophorae Flavescentiss, 4 kilograms in Radix Glycyrrhizae; 4 kilograms of Fructus Gardeniaes, 4 kilograms of Radix Curcumaes; 10 kilograms of Herba Houttuyniae, 6.5 kilograms of Folium Perillae are pulverized said medicine, cross 60 mesh sieves, are mixed the drug powder that is the chicken chronic respiratory tract disease.
Embodiment 5
Get 4.5 kilograms of Concha Haliotidis, 4 kilograms of Semen Cassiae, 4.5 kilograms of Rhizoma Atractylodis, 4.5 kilograms of Radix Platycodoniss; 3 kilograms of Radix Et Rhizoma Rhei, 3 kilograms of Radix Scutellariaes, 3 kilograms of Pericarpium Citri Reticulataes, 3 kilograms of Radix Sophorae Flavescentiss, 3 kilograms in Radix Glycyrrhizae; 3 kilograms of Fructus Gardeniaes, 3 kilograms of Radix Curcumaes; 9 kilograms of Herba Houttuyniae, 5 kilograms of Folium Perillae are pulverized said medicine, cross 60 mesh sieves, are mixed the drug powder that is the chicken chronic respiratory tract disease.
The clinical treatment test report
The cough due to lung-heat appears to 312, mouth breathing, and the white plumage broiler of clinical symptoms such as respiratory tract rale, inappetence has carried out therapeutic test with medicine of the present invention, and matched group is the powder for clearing lung-heat that certain company of market sale produces.
Test method: ill chicken is from Changzhi City suburb, Shanxi Province and small towns, and course of disease weak point person went to a doctor in 1-2 days, and the elder went to a doctor about 5 days.The clinical manifestation of chicken is that the disease pertussis is coughed, mouth breathing, shed tears, eye is wiped wing, pawl is grabbed eye, stream nose liquid, ataxia, respiratory tract gong sound, hole swelling under visible the facial area swelling, particularly socket of the eye of later stage has mucus, mucosa congestion through the visible nasal sinuses of pathological anatomy; Eye conjunctiva congestion; Tracheal mucosa is congested, mucus is arranged; Lungs one or both sides nearly bronchus end congestion, later stage larynx are only, have canescence or faint yellow cheese thing in the trachea, bronchus.Air bag is muddy, filthy thickening, has yellow cheese thing to adhere to sometimes, finally is diagnosed as chronic respiratory disease.By clinical cardinal symptom branch early symptom: sick pertussis is coughed, mouth breathing, shed tears; Mid-term symptom: ataxia, respiratory tract gong sound; Later stage symptom: hole swelling under the facial area swelling, particularly socket of the eye.Whole sick chickens are divided into four groups, and 78 every group, the early, middle and late phase case of each group as far as possible equally.First group of Drug therapy with present embodiment 1; Second group of Drug therapy with present embodiment 2; The 3rd group of Drug therapy with present embodiment 3; The 4th group compares Drug therapy with powder for clearing lung-heat.The drug effect method is that dosage, the chick by every adult chicken 5g powder reduces by half, and reconstitutes with boiled water, waits temperature and irritates clothes, treats continuously 5 days.Result of the test is seen table 1.
Statistical method: effective percentage=healing number+significant figure/treatment sum.
The therapeutic outcome of table 1 medicine of the present invention and control drug
Result of the test shows; All embodiment medicines of the present invention all have curative effect preferably to the treatment of the respiratory tract disease of chicken, and the average cure rate of three embodiment is 82.2%, and average effectiveness level is 95.2%; And the cure rate of contrast is 44.9%; Effective percentage is 62.8%, and through statistical analysis, the cure rate of medicine of the present invention and effective percentage comparison all are utmost point significant difference (P ﹤ 0.01) according to medicine.Medicine of the present invention is described from clinical efficacy, chicken chronic respiratory tract disease therapeutic effect obviously is better than control drug, and have fast, the eutherapeutic characteristics of curative effect.

Claims (3)

1. the medicine of treatment chicken chronic respiratory tract disease is characterized in that being processed by the raw material of Chinese medicine medicine of following mass parts: Concha Haliotidis 45 ~ 50, Semen Cassiae 40 ~ 50, Rhizoma Atractylodis 45 ~ 50, Radix Platycodonis 45 ~ 50, Radix Et Rhizoma Rhei 30 ~ 40, Radix Scutellariae 30 ~ 40, Pericarpium Citri Reticulatae 30 ~ 40, Radix Sophorae Flavescentis 30 ~ 40, Radix Glycyrrhizae 30 ~ 40, Fructus Gardeniae 30 ~ 40, Radix Curcumae 30 ~ 40, Herba Houttuyniae 90 ~ 100, Folium Perillae 50 ~ 65.
2. the medicine of treatment chicken chronic respiratory tract disease according to claim 1 is characterized in that being processed by the raw material of Chinese medicine medicine of following mass parts: Concha Haliotidis 50, Semen Cassiae 50, Rhizoma Atractylodis 50, Radix Platycodonis 50, Radix Et Rhizoma Rhei 40, Radix Scutellariae 40, Pericarpium Citri Reticulatae 40, Radix Sophorae Flavescentis 40, Radix Glycyrrhizae 40, Fructus Gardeniae 35, Radix Curcumae 35, Herba Houttuyniae 100, Folium Perillae 60.
3. the method for preparing of the medicine of claim 1 treatment chicken chronic respiratory tract disease, it is characterized in that the raw material of Chinese medicine medicated powder of said mass parts is broken, sieve, be mixed and made into powder.
CN2012102017436A 2012-06-19 2012-06-19 Medicament for treating chronic respiratory disease of chicken and preparation method thereof Pending CN102688457A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103948690A (en) * 2014-05-12 2014-07-30 中国农业科学院兰州畜牧与兽药研究所 Traditional Chinese medicinal composition for preventing and treating cough asthma due to lung-heat of chicken
CN105998321A (en) * 2016-05-10 2016-10-12 烟台东和生态农牧科研所 Feed additive for treating and preventing broiler mycoplasmosis and preparation method thereof
CN106138985A (en) * 2015-04-08 2016-11-23 黄旺 A kind of medicine treating mycoplasma gallinarum disease
CN106955325A (en) * 2016-01-11 2017-07-18 天津嘉创生物科技有限公司 Treat Chinese and Western medicine compound mixture of broiler chicken chronic respiratory and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN1292277A (en) * 2000-09-29 2001-04-25 王建功 Medicine for curing chicken disease of respiratory tract
CN101439175A (en) * 2008-12-25 2009-05-27 杭州万得富生物技术有限公司 Chinese medicine preparation for treating nephropathogenic infectious bronchitis in chicken
CN101884691A (en) * 2010-07-13 2010-11-17 杨建彬 Formula of traditional Chinese medicine for treating respiratory diseases of chicken

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
CN1292277A (en) * 2000-09-29 2001-04-25 王建功 Medicine for curing chicken disease of respiratory tract
CN101439175A (en) * 2008-12-25 2009-05-27 杭州万得富生物技术有限公司 Chinese medicine preparation for treating nephropathogenic infectious bronchitis in chicken
CN101884691A (en) * 2010-07-13 2010-11-17 杨建彬 Formula of traditional Chinese medicine for treating respiratory diseases of chicken

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李忠武等: "中西结合治疗蛋鸡霉形体病", 《湖北畜牧兽医》 *
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103948690A (en) * 2014-05-12 2014-07-30 中国农业科学院兰州畜牧与兽药研究所 Traditional Chinese medicinal composition for preventing and treating cough asthma due to lung-heat of chicken
CN103948690B (en) * 2014-05-12 2016-01-20 中国农业科学院兰州畜牧与兽药研究所 A kind of Chinese medicine composition for preventing and treating chicken lung-heat cough with asthma
CN106138985A (en) * 2015-04-08 2016-11-23 黄旺 A kind of medicine treating mycoplasma gallinarum disease
CN106955325A (en) * 2016-01-11 2017-07-18 天津嘉创生物科技有限公司 Treat Chinese and Western medicine compound mixture of broiler chicken chronic respiratory and preparation method thereof
CN105998321A (en) * 2016-05-10 2016-10-12 烟台东和生态农牧科研所 Feed additive for treating and preventing broiler mycoplasmosis and preparation method thereof

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Application publication date: 20120926