CN104523871A - Traditional Chinese medicine composition treating chicken rhinitis and preparing method of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition treating chicken rhinitis and preparing method of traditional Chinese medicine composition Download PDFInfo
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- CN104523871A CN104523871A CN201510005128.1A CN201510005128A CN104523871A CN 104523871 A CN104523871 A CN 104523871A CN 201510005128 A CN201510005128 A CN 201510005128A CN 104523871 A CN104523871 A CN 104523871A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
- A61K36/268—Asarum (wild ginger)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
Abstract
The invention relates to a traditional Chinese medicine composition treating chicken rhinitis. The traditional Chinese medicine is prepared through ephedra, monkshood, asarum, violet magnolia, cocklebur fruit, the root bark of white mulberry and mint. The traditional Chinese medicine composition can be powder. The preparing method of the traditional Chinese medicine composition comprises the steps that firstly, various traditional Chinese medicines are weighed according to the formula ratio; secondly, pressure reduction drying under the temperature of 40 DEG C to 70 DEG C is carried out till complete drying; thirdly, the dried medicine materials are crushed and pass a 40-100-mesh sieve; fourthly, the crushed medicine materials are packaged in bags, the weight of each bag ranges from 100 g to 200 g, and then finished products are obtained. The provided traditional Chinese medicine composition can effectively treat the chicken rhinitis, and the cure rate reaches 95 percent or higher.
Description
Technical field
The invention belongs to Chinese veterinary drug preparation field, especially a kind ofly treat Chinese medicine composition of chicken rhinitis and preparation method thereof.
Background technology
Chicken rhinitis is a kind of Acute respiratory infectious disease of the chicken caused by haemophilus paragallinarum, it is characterized in that nose and paranasal sinuses inflammation, sneeze, stream nose liquid, face swelling, conjunctivitis etc.Primary disease can occur in Growing Chicken group and laying hen group, and its economic loss caused comprises chicken growth retardation, mortality increases, and egg production significantly declines (10% ~ 40%), carrys out larger harm to poultry industrial belt.Infectious coryza of chicken is worldwide distribution, the most common with the countries and regions being in temperate zone.China at present existing ten Duo Ge provinces and cities reported the generation of primary disease.
Primary disease can infect the chicken at various age, along with the increase susceptibility of chicken age in days strengthens.Under natural conditions with Growing Chicken and Adult Chicken multiple, especially with laying hen occur more.Except chicken morbidity, also have turkey that the report of this disease occurs.All can occur throughout the year, but multiple with cold season.This sick its course of disease of generation separately about 3 ~ 4 weeks, seldom dead chicken during onset peak, but start to take a turn for the better popular later stage chicken group, when egg production is gone up gradually, usually other bacterial diseasees of secondary, the course of disease is extended, and death increases.Once there is primary disease in chicken house, often pollute the whole audience, cause other hen houses of the right age chicken phase secondary disease, almost none is escaped by luck.Sick chicken and the chicken that carries disease germs are the main infection sources of primary disease.Circulation way is based on the spittle, dust through respiratory tract infection, and next drinking-water by pollution, feedstuff are through transmission.Generation and the environmental factors of infectious coryza of chicken have much relations, and every factor that Abwehrkraft des Koepers can be made to decline all can become predisposing factors.As excessive in chicken population density, improper ventilation, abrupt change of climate etc.
This pathogenetic feature is that incubation period is short, propagates rapidly, just can involve full group in the short time.Sickness rate is high, but the death of chicken and feeding and management whether proper, whether treatment in time and have direct relation with or without other bacterial disease secondary.Sick chicken down in spirits, necking down of hanging one's head, appetite obviously reduces.See that then transfer slurry property viscous secretion to, chicken gets rid of head sometimes, sneeze from nostril outflow water sample juice at first.The inflammation of eye conjunctiva, eyelid swelled, what have sheds tears.Side or two face swelling.The visible lower jaw part of the sick chicken of part or wattle edema.Growing Chicken shows as undergrowth, and laying hen egg production obviously declines.The chicken group being in egg-laying peak lays eggs in significantly declining, and particularly Breeder hens almost has no harvest.Aged chicken morbidity egg production fall is less.Generally chicken death is less, often has dead chicken to occur in popular later stage chicken group, and majority is thin and weak chicken, or caused by other bacterial disease secondary infection, does not have obvious peak mortality.
Primary disease this disease treatment at present mainly relies on sulfa drugs.But sulfa drugs existence easily produces the unfavorable factor such as drug resistance, the restriction use of outlet group.Therefore market in urgent need replaces product to be used for clinical treatment.China's natural resources of Chinese medicinal materials enriches, and therefore exploitation is a kind of evident in efficacy, and the Chinese medicine preparation that cure rate is high has wide market prospect.
Summary of the invention
The problem to be solved in the present invention is: overcome the deficiencies in the prior art, provide a kind of evident in efficacy, cure rate is high, the Chinese medicine composition that has no side effect.
Another technical problem that the present invention will solve is: provide a kind of Chinese medicine formula for the treatment of chicken rhinitis.
Another technical problem that the present invention will solve is: the preparation method providing the powder of above-mentioned Chinese medicine composition.
For solving the problems of the technologies described above, the technical solution used in the present invention is: a kind of Chinese medicine composition for the treatment of chicken rhinitis, is characterized in that: be prepared from by the raw material of following mass fraction: Herba Ephedrae 10-20 part, Radix Aconiti Lateralis Preparata 10-20 part, Herba Asari 10-20 part, Flos Magnoliae 10-20 part, Fructus Xanthii 10-20 part, Cortex Mori 10-20 part, Herba Menthae 10-20 part.
Further, the mass fraction of the optimum feed stock of this Chinese medicine composition is as follows: 20 parts, Herba Ephedrae, Radix Aconiti Lateralis Preparata 15 parts, Herba Asari 15 parts, Flos Magnoliae 15 parts, Fructus Xanthii 15 parts, Cortex Mori 15 parts, Herba Menthae 10 parts.
Further, this Chinese medicine composition is the various conventional extract oral medicine dosage form containing or do not contain pharmaceutic adjuvant.
Further, described preparation can be powder.
Further, the preparation method of the powder of said composition is: (1) takes each Chinese medicine by formula ratio; (2) low-temperature reduced-pressure is dry until dry completely; (3) pulverizing medicinal materials of will dry, sieves; (4) be distributed into bag, get product.
The advantage that the present invention has and good effect are:
(1) this prescription is according to tcm theory, scientific compatibility, has that cold expelling dispels the wind, effect of consciousness and resuscitation restoring, inducing diuresis to remove edema, through clinical verification determined curative effect, cure rate can reach more than 95%, solves the present situation that clinical treatment chicken rhinitis can only rely on sulfonamide.
(2) pharmacology of each raw material of Chinese medicine of the present invention is:
Herba Ephedrae: relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, inducing diuresis to remove edema;
Radix Aconiti Lateralis Preparata: recuperating depleted YANG and rescuing the patient from collapse, dispersing cold for relieving pain;
Herba Asari: cold expelling dispels the wind, sensible;
Flos Magnoliae: dispersing wind-cold, clearing the nasal passage;
Fructus Xanthii: dispersing wind and cold, clearing the nasal passage;
Cortex Mori: eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema;
Herba Menthae: refresh oneself, throat, consciousness and resuscitation restoring;
Among formula, Herba Ephedrae joins Radix Aconiti Lateralis Preparata, Herba Asari expelling wind and cold, induces sweat sensible, and be aided with Flos Magnoliae, Fructus Xanthii, Herba Menthae can on the basis strengthening sensible cold expelling, consciousness and resuscitation restoring reaches the object of relieving exterior-interior syndrome.Cortex Mori coordinates Herba Ephedrae inducing diuresis to remove edema, can solve the women's head-ornaments that chicken rhinitis causes and swell.
Detailed description of the invention
Be further described the present invention below by specific embodiment, following examples are descriptive, are not determinate, can not limit protection scope of the present invention with this.
Embodiment 1
Treat a Chinese powder medicine for chicken rhinitis, the parts by weight of each raw material are as follows:
20 parts, Herba Ephedrae, Radix Aconiti Lateralis Preparata 15 parts, Herba Asari 15 parts, Flos Magnoliae 15 parts, Fructus Xanthii 15 parts, Cortex Mori 15 parts, Herba Menthae 10 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by formula ratio; (2) 60 DEG C of drying under reduced pressure are until dry completely; (3) pulverizing medicinal materials of will dry, crosses 60 mesh sieves; (4) be distributed into 200g every bag, obtain finished product.
Embodiment 2
Treat a Chinese powder medicine for chicken rhinitis, the parts by weight of each raw material are as follows:
15 parts, Herba Ephedrae, Radix Aconiti Lateralis Preparata 15 parts, Herba Asari 10 parts, Flos Magnoliae 15 parts, Fructus Xanthii 15 parts, Cortex Mori 15 parts, Herba Menthae 10 are prepared from.Its preparation method is: (1) takes each Chinese medicine by formula ratio; (2) 60 DEG C of drying under reduced pressure are until dry completely; (3) pulverizing medicinal materials of will dry, crosses 60 mesh sieves; (4) be distributed into 200g every bag, obtain finished product.
Embodiment 3
Treat a Chinese powder medicine for chicken rhinitis, the parts by weight of each raw material are as follows:
20 parts, Herba Ephedrae, Radix Aconiti Lateralis Preparata 10 parts, Herba Asari 15 parts, Flos Magnoliae 15 parts, Fructus Xanthii 10 parts, Cortex Mori 15 parts, Herba Menthae 10 parts are prepared from.Its preparation method is: 1) take each Chinese medicine by formula ratio; (2) 60 DEG C of drying under reduced pressure are until dry completely; (3) pulverizing medicinal materials of will dry, crosses 60 mesh sieves; (4) be distributed into 200g every bag, obtain finished product.
Clinical trial
Experiment 1:
10000, certain hurdle broiler that chicken farm, Hebei province is raised, falls ill for 2000 simultaneously.According to characteristics of incidence and clinical symptoms, be judged to be chicken rhinitis.Sick chicken is divided into two groups at random, and wherein one group 1000 only gives the Chinese medicine obtained by embodiment 1, and spice is fed, and every bag of 200g evenly admixes in 150kg feedstuff, allows and suffers from chicken free choice feeding, once a day, be used in conjunction three days.Another group 1000 gives sulfamonomethoxine sodium, is used in conjunction three days.Use Chinese drug-treated group cure rate 95% after three days.Sulfanilamide group is cure rate 85% after three days.This shows, Chinese drug-treated group is obviously better than sulfanilamide group.
The above, be only preferred embodiments of the present invention, is illustrative instead of determinate, can list several embodiments according to limited range, therefore in the change do not departed under general plotting of the present invention and amendment, should belong within protection scope of the present invention.
Claims (7)
1. one kind is used for the treatment of the Chinese medicine composition of chicken rhinitis, it is characterized in that, be prepared from by the raw material of following mass fraction: Herba Ephedrae 10-20 part, Radix Aconiti Lateralis Preparata 10-20 part, Herba Asari 10-20 part, Flos Magnoliae 10-20 part, Fructus Xanthii 10-20 part, Cortex Mori 10-20 part, Herba Menthae 10-20 part.
2. the Chinese medicine composition for the treatment of chicken rhinitis according to claim 1, is characterized in that: the mass fraction of optimum feed stock is as follows:
20 parts, Herba Ephedrae, Radix Aconiti Lateralis Preparata 15 parts, Herba Asari 15 parts, Flos Magnoliae 15 parts, Fructus Xanthii 15 parts, Cortex Mori 15 parts, Herba Menthae 10 parts.
3. the Chinese medicine composition for the treatment of chicken rhinitis according to claim 3, is characterized in that: described preparation can be powder.
4. prepare a method for the Chinese medicine composition for the treatment of chicken rhinitis as claimed in claim 3, it is characterized in that, preparation method is: (1) takes each Chinese medicine by formula ratio; (2) low-temperature reduced-pressure is dry until dry completely; (3) pulverizing medicinal materials of will dry, sieves; (4) be distributed into bag, get product.
5. the preparation method of the Chinese medicine composition for the treatment of chicken rhinitis according to claim 4, is characterized in that: drying under reduced pressure temperature is 40-70 DEG C.
6. the preparation method of the Chinese medicine composition for the treatment of chicken rhinitis according to claim 4, is characterized in that: passing-screen size is 40-100 order.
7. the preparation method of the Chinese medicine composition for the treatment of chicken rhinitis according to claim 4, is characterized in that: packing specification is 100-200g/ bag.
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| CN201510005128.1A CN104523871A (en) | 2015-01-06 | 2015-01-06 | Traditional Chinese medicine composition treating chicken rhinitis and preparing method of traditional Chinese medicine composition |
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| CN201510005128.1A CN104523871A (en) | 2015-01-06 | 2015-01-06 | Traditional Chinese medicine composition treating chicken rhinitis and preparing method of traditional Chinese medicine composition |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105998483A (en) * | 2016-06-27 | 2016-10-12 | 瓮安县鸿黔农产品开发有限责任公司 | Medicine for treating chicken rhinitis and making method thereof |
| CN110585316A (en) * | 2019-09-20 | 2019-12-20 | 河南焱地农牧科技有限公司 | Traditional Chinese medicine preparation for treating infectious rhinitis of poultry |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101209293A (en) * | 2006-12-25 | 2008-07-02 | 天津市润拓生物技术有限公司 | Chinese medicinal granule with heat-clearing, detoxication, wind-expelling and cold-expelling efficacy |
-
2015
- 2015-01-06 CN CN201510005128.1A patent/CN104523871A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101209293A (en) * | 2006-12-25 | 2008-07-02 | 天津市润拓生物技术有限公司 | Chinese medicinal granule with heat-clearing, detoxication, wind-expelling and cold-expelling efficacy |
Non-Patent Citations (2)
| Title |
|---|
| 许剑琴等: "《中兽医学现代化进展》", 31 July 2001, 中国农业大学出版社 * |
| 高琳: "《方剂学歌诀白话解》", 31 March 2013, 北京科学技术出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105998483A (en) * | 2016-06-27 | 2016-10-12 | 瓮安县鸿黔农产品开发有限责任公司 | Medicine for treating chicken rhinitis and making method thereof |
| CN110585316A (en) * | 2019-09-20 | 2019-12-20 | 河南焱地农牧科技有限公司 | Traditional Chinese medicine preparation for treating infectious rhinitis of poultry |
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Application publication date: 20150422 |