CN103416812B - Zinc rhizoma polygonati oral liquid and preparation technology thereof - Google Patents
Zinc rhizoma polygonati oral liquid and preparation technology thereof Download PDFInfo
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Abstract
The invention belongs to the field of health-care products of traditional Chinese medicines, and particularly relates to a zinc rhizoma polygonati oral liquid and a preparation technology thereof. The Zinc polygonatum oral liquid is prepared by the following raw materials in parts by weight: 15-25 parts of zinc gluconate, 15-25 parts of rhizoma polygonati, 8-12 parts of radix pseudostellariae, 8-12 parts of polygonatum, 15-25 parts of astragalus membranaceus, 10-15 parts of codonopsis pilosula, 10-15 parts of radix paeoniae alba, 10-15 parts of largehead atractylodes rhizome, 10-15 parts of Chinese yam, 8-12 parts of angelica sinensis, 8-12 parts of fleece-flower root, 8-12 parts of malt, 8-12 parts of rice sprout, 4-8 parts of medicated leaven, 4-8 parts of endothelium corneum gigeriae galli, 8-12 parts of rhizoma atractylodis, 8-12 parts of charred fructus crataegi, 8-12 parts of fossilizid, 8-12 parts of ostracean, 100-200 parts of white granulated sugar, and 1000-1200 parts of water. The zinc rhizoma polygonati oral liquid has effects of Qi-tonifying and spleen-tonifying, Yin-nourishing and body fluid-generating, and essence-boosting and bone-invigorating, and functions of permanent cure for rickets caused by hidrosis, night terror, night cry, inappetence, dyspepsia, developmental retardation and the like and children with malnutrition in Ca and Zn.
Description
Technical field
The invention belongs to traditional Chinese medicine health care product field, particularly a kind of zinc rhizoma polygonati oral liquid and preparation technology.
Background technology
Zinc is the important composition composition of many enzymes in body, has enhancing development, improves the effects such as the sense of taste.During shortage, growth retardation, impotence generandi, wound are not easily healed, body is weak, also conjunctivitis, stomatitis, glossitis, anorexia, chronic diarrhea, ageusia and nervous symptoms etc. can occur.Zinc is particularly important to upgrowth and development of children.Zinc gluconate is zinc tonic, is mainly used in baby and old age, the growth retardation that gravid woman causes because lacking zinc, malnutritive, apositia, the diseases such as recurrent oral ulceration.As the Main Ingredients and Appearance of Zinc Gluuconate Oral Solution, zinc gluconate and sealwort also have other compatibility, as " compound formulation for the treatment of nutritional iron deficiency anemia " CN94118569.9, it is primarily of compositions such as Six-element Chinese drug-treated group and zinc gluconate such as sealwort, hawthorn, the red sage root, rhizoma atractylodis, Semen Lablab Album, the fruit ofs Chinese magnoliavine, and it has continue spleen benefit gas, hereby sun and enriches blood and directly supplement the effect of the necessary iron of human body, Zn-ef ficiency; And for example " a kind of compound and preparation method and application with kidney invigorating and Yang strengthening function " CN200810019371.9, the compound be made up of effective spice such as arillus longan, sealwort, oyster, deer blood meal, fructus alpiniae oxyphyllae, the fruit of Chinese wolfberry, raspberry, Semen sesami nigrum, Gorgon fruit, Chinese yam, Chinese cassia tree, zinc gluconate, can strengthen muscles and bones, improve the health, strengthen brain function, eliminate One's spirits are drooping, the effects such as failure of memory.
Summary of the invention
The object of this invention is to provide a kind of air making-up and spleen enlivening, nourishing Yin and promoting production of body fluid, the zinc rhizoma polygonati oral liquid of the strong bone of benefit essence and preparation technology.
One of technical solution of the present invention is:
It is made up of the raw material comprising following weight parts: zinc gluconate 15-25 parts, sealwort 15-25 parts, radix pseudostellariae 8-12 parts, radix polygonati officinalis 8-12 parts, the Radix Astragali 15-25 parts, Radix Codonopsis 10-15 parts, the root of herbaceous peony 10-15 parts, Rhizoma Atractylodis Macrocephalae preparata 10-15 parts, RHIIZOMA DIOSCOREAE from Henan of China 10-15 parts, Radix Angelicae Sinensis 8-12 parts, the tuber of multiflower knotweed 8-12 parts, 8-12 parts, Fructus Hordei Germinatus, rice sprout 8-12 parts, Divine Comedy 4-8 parts, the membrane of a chicken's gizzard 4-8 parts, rhizoma atractylodis 8-12 parts, charred FRUCTUS CRATAEGI 8-12 parts, keel 8-12 parts, oyster 8-12 parts, white granulated sugar 100-200 parts, 1000-1200 parts, water.
Two of technical solution of the present invention is:
First by sealwort, radix pseudostellariae, radix polygonati officinalis, the Radix Astragali, Radix Codonopsis, the root of herbaceous peony, Rhizoma Atractylodis Macrocephalae preparata, RHIIZOMA DIOSCOREAE from Henan of China, Radix Angelicae Sinensis, the tuber of multiflower knotweed, Fructus Hordei Germinatus, rice sprout, Divine Comedy, the membrane of a chicken's gizzard, rhizoma atractylodis, charred FRUCTUS CRATAEGI, keel, oyster, add water after each decoction secondary, filter after removing slag, after concentrated, let cool, add ethanol, stir evenly placement 18-36 hours, after ethanol to be recycled, filtrate is concentrated into medicinal extract shape, separately by zinc gluconate, white granulated sugar is dissolved in water, being added in medicinal extract, stirring evenly to dissolving completely, dilute with water, filter, then add water; Refrigeration, filters, is packaged in 10 milliliters of bottles and seals; With boiling water sterilizing and get final product.
Sealwort, radix pseudostellariae, radix polygonati officinalis boosting qi and nourishing yin in side of the present invention, invigorating the spleen benefit lung promotes the production of body fluid; The Radix Astragali, Radix Codonopsis, the root of herbaceous peony, Rhizoma Atractylodis Macrocephalae preparata, RHIIZOMA DIOSCOREAE from Henan of China benefiting qi and nourishing blood invigorating the spleen benefit are defended, strengthening exterior and reducing sweat; Radix Angelicae Sinensis, tuber of multiflower knotweed replenishing vital essence and blood, life essence-filling, marrow-benefitting, black hair; Fructus Hordei Germinatus, rice sprout, Divine Comedy, interior gold, rhizoma atractylodis help digestion except long-pending, and the stomach invigorating of fortune spleen, promotes calcium zinc-iron alloy solution, and calm the nerves arrest sweating, controlling nocturnal emission with astringent drugs of keel, oyster is good for bone, and is rich in natural calcareous.All medicines share, and play air making-up and spleen enlivening altogether, nourishing Yin and promoting production of body fluid, the effect of the strong bone of benefit essence.To the merit that disease the having such as children's's hidrosis, sleep terror fright at night, the morbid night crying of babies and poor appetite, indigestion, hypoevolutism are effected a permanent cure.
In side, zinc gluconate is zinc tonic, is mainly used in the growth retardation that children's causes because lacking zinc, malnutritive, the diseases such as apositia.
Try out through 198 children, result is as follows.
1, basic condition: amount to 198 children, mostly substantially meet " disease of tcm Standardization of diagnosis and curative effect " Middle nutrition diagnosis of anemia standard, but symptom is all lighter.At random all medication persons are divided into two groups, oral liquid (embodiment 1) group 129 example, 69 examples are organized in contrast (syrup).
2, methods for the treatment of: oral liquid group, control group equal every day oral twice, each 20ml.The course for the treatment of is 1 month.
3, curative effect determinate standard is according to State Administration of Traditional Chinese Medicine's " disease of tcm Standardization of diagnosis and curative effect " Middle nutrition anaemia curative effect determinate standard, through suitably adjusting formulation.
1. effective: symptom, sign are obviously improved.
2. effective: symptom, sign all take a favorable turn.
3. invalid: symptom, sign are not improved or add severe one.
4, statistical method adopts t inspection and X 2 to check.
5, result
Two groups of medication person's Clinical efficacy comparisons, effective 66 examples in oral liquid group 129 example, effective 51 examples, invalid 12 examples, total effective rate is 90.7%; Effective 0 example in control group 69 example, effective 8 examples, invalid 61 examples, total effective rate 11.6%.Show that oral liquid group total effective rate is greater than control group by above data, through t inspection, two groups of difference tool statistical significances (P<0.001).
Detailed description of the invention
The present invention specifically can be implemented by the technology illustrated in summary of the invention, can be conducted further description by the following examples to the present invention, but scope of the present invention is not limited to following embodiment.
Embodiment 1:
Zinc gluconate 20 parts, sealwort 20 parts, radix pseudostellariae 10 parts, radix polygonati officinalis 10 parts, the Radix Astragali 20 parts, Radix Codonopsis 12 parts, the root of herbaceous peony 12 parts, Rhizoma Atractylodis Macrocephalae preparata 12 parts, RHIIZOMA DIOSCOREAE from Henan of China 12 parts, Radix Angelicae Sinensis 10 parts, the tuber of multiflower knotweed 10 parts, 10 parts, Fructus Hordei Germinatus, rice sprout 10 parts, Divine Comedy 5 parts, the membrane of a chicken's gizzard 5 parts, rhizoma atractylodis 10 parts, charred FRUCTUS CRATAEGI 10 parts, keel 10 parts, oyster 10 parts, white granulated sugar 150 parts, 1000 parts, water.
Preparation technology: first by sealwort, radix pseudostellariae, radix polygonati officinalis, the Radix Astragali, Radix Codonopsis, the root of herbaceous peony, Rhizoma Atractylodis Macrocephalae preparata, RHIIZOMA DIOSCOREAE from Henan of China, Radix Angelicae Sinensis, the tuber of multiflower knotweed, Fructus Hordei Germinatus, rice sprout, Divine Comedy, the membrane of a chicken's gizzard, rhizoma atractylodis, charred FRUCTUS CRATAEGI, keel, oyster, add water after each decoction secondary, filter after removing slag, after concentrated, let cool, add ethanol, stir evenly placement 18-36 hours, after ethanol to be recycled, filtrate is concentrated into medicinal extract shape, separately by zinc gluconate, white granulated sugar is dissolved in water, being added in medicinal extract, stirring evenly to dissolving completely, dilute with water, filter, then add water; Refrigeration, filters, is packaged in 10 milliliters of bottles and seals; With boiling water sterilizing and get final product.
Embodiment 2:
Zinc gluconate 25 parts, sealwort 15 parts, radix pseudostellariae 12 parts, radix polygonati officinalis 8 parts, the Radix Astragali 25 parts, Radix Codonopsis 10 parts, the root of herbaceous peony 15 parts, Rhizoma Atractylodis Macrocephalae preparata 10 parts, RHIIZOMA DIOSCOREAE from Henan of China 15 parts, Radix Angelicae Sinensis 8 parts, the tuber of multiflower knotweed 12 parts, 8 parts, Fructus Hordei Germinatus, rice sprout 12 parts, Divine Comedy 4 parts, the membrane of a chicken's gizzard 8 parts, rhizoma atractylodis 8 parts, charred FRUCTUS CRATAEGI 12 parts, keel 8 parts, oyster 12 parts, white granulated sugar 100 parts, 1200 parts, water.
Preparation method is as embodiment 1.
Embodiment 3:
Zinc gluconate 15 parts, sealwort 25 parts, radix pseudostellariae 8 parts, radix polygonati officinalis 12 parts, the Radix Astragali 15 parts, Radix Codonopsis 15 parts, the root of herbaceous peony 10 parts, Rhizoma Atractylodis Macrocephalae preparata 15 parts, RHIIZOMA DIOSCOREAE from Henan of China 10 parts, Radix Angelicae Sinensis 12 parts, the tuber of multiflower knotweed 8 parts, 12 parts, Fructus Hordei Germinatus, rice sprout 8 parts, Divine Comedy 8 parts, the membrane of a chicken's gizzard 4 parts, rhizoma atractylodis 12 parts, charred FRUCTUS CRATAEGI 8 parts, keel 12 parts, oyster 8 parts, white granulated sugar 200 parts, 1000 parts, water.
Preparation method is as embodiment 1.
Embodiment 4:
Zinc gluconate 25 parts, sealwort 22 parts, radix pseudostellariae 10 parts, radix polygonati officinalis 9 parts, the Radix Astragali 18 parts, Radix Codonopsis 13 parts, the root of herbaceous peony 13 parts, Rhizoma Atractylodis Macrocephalae preparata 12 parts, RHIIZOMA DIOSCOREAE from Henan of China 13 parts, Radix Angelicae Sinensis 9 parts, the tuber of multiflower knotweed 9 parts, 11 parts, Fructus Hordei Germinatus, rice sprout 11 parts, Divine Comedy 6 parts, the membrane of a chicken's gizzard 6 parts, rhizoma atractylodis 9 parts, charred FRUCTUS CRATAEGI 11 parts, keel 11 parts, oyster 11 parts, white granulated sugar 200 parts, 1200 parts, water.
Preparation method is as embodiment 1.
Claims (2)
1. a zinc rhizoma polygonati oral liquid, it is characterized in that, it is made up by following technique of the raw material of following weight parts: zinc gluconate 15-25 parts, sealwort 15-25 parts, radix pseudostellariae 8-12 parts, radix polygonati officinalis 8-12 parts, the Radix Astragali 15-25 parts, Radix Codonopsis 10-15 parts, the root of herbaceous peony 10-15 parts, Rhizoma Atractylodis Macrocephalae preparata 10-15 parts, RHIIZOMA DIOSCOREAE from Henan of China 10-15 parts, Radix Angelicae Sinensis 8-12 parts, the tuber of multiflower knotweed 8-12 parts, 8-12 parts, Fructus Hordei Germinatus, rice sprout 8-12 parts, Divine Comedy 4-8 parts, the membrane of a chicken's gizzard 4-8 parts, rhizoma atractylodis 8-12 parts, charred FRUCTUS CRATAEGI 8-12 parts, keel 8-12 parts, oyster 8-12 parts, white granulated sugar 100-200 parts, 1000-1200 parts, water,
Preparation technology is: first by sealwort, radix pseudostellariae, radix polygonati officinalis, the Radix Astragali, Radix Codonopsis, the root of herbaceous peony, Rhizoma Atractylodis Macrocephalae preparata, RHIIZOMA DIOSCOREAE from Henan of China, Radix Angelicae Sinensis, the tuber of multiflower knotweed, Fructus Hordei Germinatus, rice sprout, Divine Comedy, the membrane of a chicken's gizzard, rhizoma atractylodis, charred FRUCTUS CRATAEGI, keel, oyster, add water after each decoction secondary, filter after removing slag, after concentrated, let cool, add ethanol, stir evenly placement 18-36 hours, after ethanol to be recycled, filtrate is concentrated into medicinal extract shape, separately by zinc gluconate, white granulated sugar is dissolved in water, is added in medicinal extract, stirs evenly to dissolving completely, dilute with water, filters, then adds water; Refrigeration, filters, is packaged in 10 milliliters of bottles and seals; With boiling water sterilizing and get final product.
2. a kind of zinc rhizoma polygonati oral liquid according to claim 1, is characterized in that, it is made up of the raw material of following weight parts: zinc gluconate 20 parts, sealwort 20 parts, radix pseudostellariae 10 parts, radix polygonati officinalis 10 parts, the Radix Astragali 20 parts, Radix Codonopsis 12 parts, the root of herbaceous peony 12 parts, Rhizoma Atractylodis Macrocephalae preparata 12 parts, RHIIZOMA DIOSCOREAE from Henan of China 12 parts, Radix Angelicae Sinensis 10 parts, the tuber of multiflower knotweed 10 parts, 10 parts, Fructus Hordei Germinatus, rice sprout 10 parts, Divine Comedy 5 parts, the membrane of a chicken's gizzard 5 parts, rhizoma atractylodis 10 parts, charred FRUCTUS CRATAEGI 10 parts, keel 10 parts, oyster 10 parts, white granulated sugar 150 parts, 1000 parts, water.
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|---|---|---|---|---|
| CN100475254C (en) * | 2006-05-30 | 2009-04-08 | 北京身心康生物科技有限公司 | Anti-fatigue resistibility capsules for improving body immunity and method for making same |
| CN101143010B (en) * | 2006-09-15 | 2012-07-11 | 上海瑞品实业有限公司 | Special-purpose nutritive food for diabetes patient and its preparation method |
| CN101317977A (en) * | 2008-07-14 | 2008-12-10 | 王跃进 | Nourishing beverage particle for gestation period |
| CN101352543B (en) * | 2008-09-09 | 2010-05-12 | 李少平 | Walnut tuckahoe oral liquid and method for producing the same |
| CN101703744B (en) * | 2009-11-18 | 2011-07-06 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating palpitation and shortness of breath and preparation method thereof |
-
2013
- 2013-08-05 CN CN201310336151.XA patent/CN103416812B/en active Active
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