A kind of zinc yellow extract oral liquid and preparation technology
Technical field
The invention belongs to the traditional Chinese medicine health care product field, particularly a kind of zinc yellow extract oral liquid and preparation technology.
Background technology
The important composition composition that zinc is many enzymes in body, have enhancing development, improve the effect such as the sense of taste.During shortage, growth retardation, impotence generandi, wound are difficult for healing, body is weak, also conjunctivitis, stomatitis, glossitis, anorexia, chronic diarrhea, ageusia and nervous symptoms etc. can occur.Zinc is particularly important to upgrowth and development of children.Zinc gluconate is zinc tonic, is mainly used in baby and old age, the growth retardation that the gravid woman causes because lacking zinc, malnutrition, apositia, the diseases such as recurrent oral ulceration.Main Ingredients and Appearance as Zinc Gluuconate Oral Solution, zinc gluconate and sealwort also have other compatibility, as " compound formulation for the treatment of nutritional iron deficiency anemia " CN94118569.9, it mainly is comprised of the Six-element Chinese drug-treated group such as sealwort, hawthorn, the red sage root, rhizoma atractylodis, Semen Lablab Album, the fruit of Chinese magnoliavine and zinc gluconate etc., and it has the spleen benefit gas that continues, hereby sun is enriched blood and directly supplemented the necessary iron of human body, the effect of zinc element; " a kind of compound and preparation method and application with kidney invigorating and Yang strengthening function " CN200810019371.9 and for example, by the compound that effectively spice forms such as arillus longan, sealwort, oyster, deer blood meal, fructus alpiniae oxyphyllae, the fruit of Chinese wolfberry, raspberry, Semen sesami nigrum, Gorgon fruit, Chinese yam, Chinese cassia tree, zinc gluconate, can strengthen muscles and bones, improve the health, strengthen brain function, eliminate One's spirits are drooping, the effects such as failure of memory.
Summary of the invention
The purpose of this invention is to provide a kind of air making-up and spleen enlivening, nourishing Yin and promoting production of body fluid, zinc yellow extract oral liquid and the preparation technology of the strong bone of benefit essence.
One of technical solution of the present invention is:
It is to be made by the raw material that comprises following weight parts: 15-25 parts of zinc gluconates, 15-25 parts of sealworts, 8-12 parts of radix pseudostellariaes, 8-12 parts of radix polygonati officinalis, 15-25 parts of the Radixs Astragali, 10-15 parts of Radix Codonopsis, 10-15 parts of the root of herbaceous peonys, 10-15 parts of Rhizoma Atractylodis Macrocephalae preparatas, 10-15 parts of RHIIZOMA DIOSCOREAE from Henan of China, 8-12 parts of Radix Angelicae Sinensis, 8-12 parts of the tubers of multiflower knotweed, 8-12 parts, Fructus Hordei Germinatus, 8-12 parts of rice sprouts, 4-8 parts of Divine Comedy, 4-8 parts of thes membrane of a chicken's gizzard, 8-12 parts of rhizoma atractylodis, 8-12 parts of charred FRUCTUS CRATAEGIs, 8-12 parts of keel, 8-12 parts of oysters, 100-200 parts of white granulated sugars, 1000-1200 parts, water.
Two of technical solution of the present invention is:
First by sealwort, radix pseudostellariae, radix polygonati officinalis, the Radix Astragali, Radix Codonopsis, the root of herbaceous peony, Rhizoma Atractylodis Macrocephalae preparata, RHIIZOMA DIOSCOREAE from Henan of China, Radix Angelicae Sinensis, the tuber of multiflower knotweed, Fructus Hordei Germinatus, rice sprout, Divine Comedy, the membrane of a chicken's gizzard, rhizoma atractylodis, charred FRUCTUS CRATAEGI, keel, oyster, after adding water and respectively decocting secondary, the rear filtration of removing slag, after concentrated, let cool, and adds ethanol, stir evenly and place 18-36 hours, after ethanol to be recycled, filtrate is concentrated into to the medicinal extract shape, separately by zinc gluconate, white granulated sugar is dissolved in water, be added in medicinal extract, stir evenly to dissolving fully, dilute with water, filter, then add water; Refrigeration, filter, and is packaged in 10 milliliters of bottles and seals; With the boiling water sterilizing and get final product.
Sealwort, radix pseudostellariae, radix polygonati officinalis boosting qi and nourishing yin in side of the present invention, invigorating the spleen benefit lung promotes the production of body fluid; The Radix Astragali, Radix Codonopsis, the root of herbaceous peony, Rhizoma Atractylodis Macrocephalae preparata, RHIIZOMA DIOSCOREAE from Henan of China benefiting qi and nourishing blood invigorating the spleen benefit are defended, strengthening exterior and reducing sweat; Radix Angelicae Sinensis, tuber of multiflower knotweed replenishing vital essence and blood, life essence-filling, marrow-benefitting, black hair; Fructus Hordei Germinatus, rice sprout, Divine Comedy, interior gold, rhizoma atractylodis help digestion except long-pending, and the stomach invigorating of fortune spleen, promote calcium zinc to absorb, keel, oyster calm the nerves arrest sweating, the strong bone of controlling nocturnal emission with astringent drugs, and be rich in natural calcareous.All medicines share, and play altogether air making-up and spleen enlivening, nourishing Yin and promoting production of body fluid, the effect of the strong bone of benefit essence.The merit that disease the having such as children's's hidrosis, sleep terror fright at night, the morbid night crying of babies and poor appetite, indigestion, hypoevolutism are effected a permanent cure.
In side, zinc gluconate is zinc tonic, is mainly used in the growth retardation that children's causes because lacking zinc, malnutrition, the diseases such as apositia.
On probation through 198 children, result is as follows.
1, basic condition: amount to 198 children, mostly substantially meet alimentary anemia diagnostic criteria in " disease of tcm Standardization of diagnosis and curative effect ", but symptom is all lighter.At random all medication persons are divided into to two groups, oral liquid (embodiment 1) is organized 129 examples, and 69 examples are organized in contrast (syrup).
2, methods for the treatment of: oral liquid group, control group equal every day is oral twice, each 20ml.Be 1 month the course for the treatment of.
3, curative effect determinate standard is according to alimentary anemia curative effect determinate standard in State Administration of Traditional Chinese Medicine's " disease of tcm Standardization of diagnosis and curative effect ", through suitably adjusting and formulate.
1. produce effects: symptom, sign are obviously improved.
2. effective: symptom, sign all take a favorable turn.
3. invalid: symptom, sign are not improved or add severe one.
4, statistical method adopts t check and X 2 checks.
5, result
Two groups of medication person's Clinical efficacy comparisons, produce effects 66 examples in oral liquid group 129 examples, effective 51 examples, invalid 12 examples, total effective rate is 90.7%; Produce effects 0 example in control group 69 examples, effective 8 examples, invalid 61 examples, total effective rate 11.6%.Show that by above data oral liquid group total effective rate is greater than control group, through t check, two groups of difference tool statistical significances (P<0.001).
The specific embodiment
The present invention can specifically implement by the technology illustrated in summary of the invention, by the following examples, can conduct further description the present invention, yet scope of the present invention is not limited to following embodiment.
Embodiment 1:
20 parts of zinc gluconates, 20 parts of sealworts, 10 parts of radix pseudostellariaes, 10 parts of radix polygonati officinalis, 20 parts of the Radixs Astragali, 12 parts of Radix Codonopsis, 12 parts of the root of herbaceous peonys, 12 parts of Rhizoma Atractylodis Macrocephalae preparatas, 12 parts of RHIIZOMA DIOSCOREAE from Henan of China, 10 parts of Radix Angelicae Sinensis, 10 parts of the tubers of multiflower knotweed, 10 parts, Fructus Hordei Germinatus, 10 parts of rice sprouts, 5 parts of Divine Comedy, 5 parts of thes membrane of a chicken's gizzard, 10 parts of rhizoma atractylodis, 10 parts of charred FRUCTUS CRATAEGIs, 10 parts of keel, 10 parts of oysters, 150 parts of white granulated sugars, 1000 parts, water.
Preparation technology: first by sealwort, radix pseudostellariae, radix polygonati officinalis, the Radix Astragali, Radix Codonopsis, the root of herbaceous peony, Rhizoma Atractylodis Macrocephalae preparata, RHIIZOMA DIOSCOREAE from Henan of China, Radix Angelicae Sinensis, the tuber of multiflower knotweed, Fructus Hordei Germinatus, rice sprout, Divine Comedy, the membrane of a chicken's gizzard, rhizoma atractylodis, charred FRUCTUS CRATAEGI, keel, oyster, after adding water and respectively decocting secondary, the rear filtration of removing slag, after concentrated, let cool, and adds ethanol, stir evenly and place 18-36 hours, after ethanol to be recycled, filtrate is concentrated into to the medicinal extract shape, separately by zinc gluconate, white granulated sugar is dissolved in water, be added in medicinal extract, stir evenly to dissolving fully, dilute with water, filter, then add water; Refrigeration, filter, and is packaged in 10 milliliters of bottles and seals; With the boiling water sterilizing and get final product.
Embodiment 2:
25 parts of zinc gluconates, 15 parts of sealworts, 12 parts of radix pseudostellariaes, 8 parts of radix polygonati officinalis, 25 parts of the Radixs Astragali, 10 parts of Radix Codonopsis, 15 parts of the root of herbaceous peonys, 10 parts of Rhizoma Atractylodis Macrocephalae preparatas, 15 parts of RHIIZOMA DIOSCOREAE from Henan of China, 8 parts of Radix Angelicae Sinensis, 12 parts of the tubers of multiflower knotweed, 8 parts, Fructus Hordei Germinatus, 12 parts of rice sprouts, 4 parts of Divine Comedy, 8 parts of thes membrane of a chicken's gizzard, 8 parts of rhizoma atractylodis, 12 parts of charred FRUCTUS CRATAEGIs, 8 parts of keel, 12 parts of oysters, 100 parts of white granulated sugars, 1200 parts, water.
The preparation method is as embodiment 1.
Embodiment 3:
15 parts of zinc gluconates, 25 parts of sealworts, 8 parts of radix pseudostellariaes, 12 parts of radix polygonati officinalis, 15 parts of the Radixs Astragali, 15 parts of Radix Codonopsis, 10 parts of the root of herbaceous peonys, 15 parts of Rhizoma Atractylodis Macrocephalae preparatas, 10 parts of RHIIZOMA DIOSCOREAE from Henan of China, 12 parts of Radix Angelicae Sinensis, 8 parts of the tubers of multiflower knotweed, 12 parts, Fructus Hordei Germinatus, 8 parts of rice sprouts, 8 parts of Divine Comedy, 4 parts of thes membrane of a chicken's gizzard, 12 parts of rhizoma atractylodis, 8 parts of charred FRUCTUS CRATAEGIs, 12 parts of keel, 8 parts of oysters, 200 parts of white granulated sugars, 1000 parts, water.
The preparation method is as embodiment 1.
Embodiment 4:
25 parts of zinc gluconates, 22 parts of sealworts, 10 parts of radix pseudostellariaes, 9 parts of radix polygonati officinalis, 18 parts of the Radixs Astragali, 13 parts of Radix Codonopsis, 13 parts of the root of herbaceous peonys, 12 parts of Rhizoma Atractylodis Macrocephalae preparatas, 13 parts of RHIIZOMA DIOSCOREAE from Henan of China, 9 parts of Radix Angelicae Sinensis, 9 parts of the tubers of multiflower knotweed, 11 parts, Fructus Hordei Germinatus, 11 parts of rice sprouts, 6 parts of Divine Comedy, 6 parts of thes membrane of a chicken's gizzard, 9 parts of rhizoma atractylodis, 11 parts of charred FRUCTUS CRATAEGIs, 11 parts of keel, 11 parts of oysters, 200 parts of white granulated sugars, 1200 parts, water.
The preparation method is as embodiment 1.