CN101274077A - Medicament composition for curing children's anorexia and preparation thereof - Google Patents
Medicament composition for curing children's anorexia and preparation thereof Download PDFInfo
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- CN101274077A CN101274077A CNA2008101058381A CN200810105838A CN101274077A CN 101274077 A CN101274077 A CN 101274077A CN A2008101058381 A CNA2008101058381 A CN A2008101058381A CN 200810105838 A CN200810105838 A CN 200810105838A CN 101274077 A CN101274077 A CN 101274077A
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Abstract
The invention discloses a medicine compound used for curing child anorexia, which is prepared by the traditional Chinese medicinal materials according to weight mixture ratio as follows: 10 to 50 parts by weight of radix codonopsis pilosulae, 5 to 40 parts by weight of Indian buead, 5 to 40 parts by weight of largehead atractylodes rhizome, 5 to 30 parts by weight of common yam rhizome, 5 to 30 parts by weight of tangerine peel, 5 to 30 parts by weight of hawthorn, 5 to 20 parts by weight of massa medicata fermentata, 5 to 20 parts by weight of wheat germ, 5 to 20 parts by weight of astragalus root and 3 to 10 parts by weight of chicken's gizzard-membrane. The medicine compound has the effects of strengthening the spleen, promoting appetite, relieving dyspepsia and strengthening body immunity and exact effect of curing the child anorexia.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition and preparation method thereof, particularly relate to a kind of pharmaceutical composition for the treatment of infantile anorexia and preparation method thereof, belong to the novel technique field.
Background technology
Infantile anorexia is the common disease of department of pediatrics, be with children's more often between inappetence or go down, food-intake obviously reduces, even refusing to eat is the disease of primary symptom.Age is many based on 1～6 years old, and malnutrition can take place long-term anorexia infant, loses weight, and resistance descends, even influences intelligence development and grow up healthy and sound.
Infantile anorexia belongs to the category of cards such as Chinese medicine " anorexia ", " disliking food ", " getting ill from overeating ", " dyspepsia ".
Along with improving constantly of human living standard, the paathogenic factor of infantile anorexia is based on eating and drinking without temperance, improper feeding, and unreasonable with dietary structure, to suffer from factors such as gastrointestinal disease or general disease relevant.
Chinese medicine is in the treatment advantage that shows its uniqueness aspect the clinical treatment of infantile anorexia, and with the spleen and stomach regulating, it is main recovering the fortuneization function, is aided with benefiting vital QI and blood, promoting digestion and removing stagnation, has better therapeutic effect.
Summary of the invention
One of the object of the invention is to provide a kind of pharmaceutical composition for the treatment of infantile anorexia, and this product has spleen benefiting and stimulating the appetite, relieving dyspepsia, the effect of enhancing human body immunity power.
Two of the object of the invention is to provide this preparation of drug combination method.
The effect that Radix Codonopsis has QI invigorating, promotes the production of body fluid, nourishes blood, " book on Chinese herbal medicine justice " is loaded with: " power energy spleen reinforcing nourishing the stomach, the lung moistening and production of body fluid promoting, gas in the strong fortune, this is very mutually not far away with Radix Ginseng.Especially valuable person: then spleen invigorating and not dry; Taste stomach-Yin and wet; Lung moistening and do not violate cold and cool; Nourish blood and do not grow partially and be bored with; Inspire clear sun, gas in the vibration and do not have dry fraud just." this product contains saponin, vitamin and necessary inorganic elements of multiple human body and aminoacid etc., has the enhancing body resistance, regulates gastrointestinal motility, antiulcer, the gastric acid inhibitory secretion reduces effects such as pepsin activity; Poria has the effect of spleen-benefiting mind-tranquilizing, energy spleen invigorating invigorating middle warmer, Yixinningshen; The Rhizoma Atractylodis Macrocephalae has the effect of air making-up and spleen enlivening, and " book on Chinese herbal medicine converges and says " is loaded with: " Rhizoma Atractylodis Macrocephalae is to foster taste, and numbness falls in wet dissipation, helps digestion except that the key medicine of painful abdominal mass.Insufficiency of the spleen unstrong, art can be mended it; Insufficiency of stomach is not received, and art can help it." the clinical deficiency of spleen-QI and stomach-QI that is used for the treatment of, fortuneization is unable, anorexia and loose stool, distension and fullness in the abdomen, cards such as the soft Mental fatigue of limb; Rhizoma Dioscoreae has supplementing QI and nourishing YIN, the effect of spleen reinforcing lung kidney, and this product has nourishing, and is aid digestion waits effect; Pericarpium Citri Reticulatae has promoting the circulation of QI to relieve pain, spleen invigorating and in merit; Fructus Crataegi can increase the secretion of digestive enzyme in the stomach for the key medicine of the greasy meat stagnation of digestion, and facilitating digestion, the contained lipase composition of this product can promote the decomposition of fat, and multiple organic acid composition can improve protease activities, makes meat be easy to digestion; Massa Medicata Fermentata has the merit of promoting digestion and invigorating the stomach and middle antidiarrheal, is usually used in treating eating accumulation disease; Fructus Hordei Germinatus has the effect of promoting digestion and invigorating the stomach, can promote the digestion of starchiness food; The Radix Astragali is good at invigorating the spleen and replenishing QI, and has the effect of enhancing human body immunity function; Endothelium Corneum Gigeriae Galli has the effect of promoting digestion and invigorating the stomach, and this product has the effect of stronger digestion food stagnation, and the energy invigorating the spleen and stomach, secretory volume, acidity and the eupepsy of gastric juice are all strengthened, gastric motility strengthens, and gastric emptying speeds up, the clinical various dyspepsia cards such as treating rice and flour potato meat that are widely used in.
The pharmaceutical composition of treatment infantile anorexia provided by the invention is to be made by the Chinese crude drug of following weight proportioning:
Radix Codonopsis 10～50 weight portion Poria 5～40 weight portions
The Rhizoma Atractylodis Macrocephalae 5～40 weight portion Rhizoma Dioscoreaes 5～30 weight portions
Pericarpium Citri Reticulatae 5～30 weight portion Fructus Crataegis 5～30 weight portions
Massa Medicata Fermentata 5～20 weight portion Fructus Hordei Germinatus 5～20 weight portions
The Radix Astragali 5～20 weight portion Endothelium Corneum Gigeriae Galli 3～10 weight portions
Further, the pharmaceutical composition of treatment infantile anorexia provided by the invention, its composition can be adopted as especially:
Radix Codonopsis 30 weight portion Poria 20 weight portions
The Rhizoma Atractylodis Macrocephalae 20 weight portion Rhizoma Dioscoreaes 10 weight portions
Pericarpium Citri Reticulatae 10 weight portion Fructus Crataegis 10 weight portions
Massa Medicata Fermentata 10 weight portion Fructus Hordei Germinatus 10 weight portions
The Radix Astragali 15 weight portion Endothelium Corneum Gigeriae Galli 5 weight portions
The present invention can be processed into oral liquid, syrup, granule, tablet, capsule, the arbitrary dosage form of chewable tablet in conjunction with modern preparation technique.
The preparation of drug combination method of treatment infantile anorexia provided by the invention is as follows:
(1) gets Radix Codonopsis, Poria, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Pericarpium Citri Reticulatae, Fructus Crataegi, Massa Medicata Fermentata, Fructus Hordei Germinatus, the Radix Astragali, Endothelium Corneum Gigeriae Galli, be ground into coarse powder, decoct 2～3 times with 8～12 times of water gagings, each 1～3 hour, decocting liquid filters, and is concentrated into relative density and is 1.10～1.30 clear paste, and is standby;
(2) get above-mentioned clear paste, formulation method adds the suitable formulations adjuvant routinely, molding, and packing, check, promptly.
The specific embodiment
Embodiment 1
Prescription is formed:
Radix Codonopsis 60g Poria 40g Rhizoma Atractylodis Macrocephalae 40g
Rhizoma Dioscoreae 20g Pericarpium Citri Reticulatae 20g Fructus Crataegi 20g
Massa Medicata Fermentata 20g Fructus Hordei Germinatus 20g Radix Astragali 30g
Endothelium Corneum Gigeriae Galli 10g sucrose 570g flavoring orange essence 1ml
Sodium benzoate 3g
Make 1000ml altogether
Preparation method:
(1) get Radix Codonopsis, Poria, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Pericarpium Citri Reticulatae, Fructus Crataegi, Massa Medicata Fermentata, Fructus Hordei Germinatus, the Radix Astragali, Endothelium Corneum Gigeriae Galli, be ground into coarse powder, add 12 times of water gagings and decocted 2 hours, decocting liquid filters; Medicinal residues add 10 times of water gagings to be fried in shallow oil 1 hour, and decocting liquid filters; Medicinal residues add 8 times of water gagings again and decocted 1 hour, and decocting liquid filters, and merging filtrate is evaporated to relative density and is 1.17 clear paste under 60 ℃ of conditions, standby;
(2) get above-mentioned clear paste, left standstill 24 hours, filter filtrate for later use;
(3) get step (2) gained filtrate, add sucrose, flavoring orange essence, sodium benzoate, mix homogeneously adds water to ormal weight, embedding, packing, check, promptly.
Embodiment 2
Prescription is formed:
Radix Codonopsis 120g Poria 80g Rhizoma Atractylodis Macrocephalae 80g
Rhizoma Dioscoreae 40g Pericarpium Citri Reticulatae 40g Fructus Crataegi 40g
Massa Medicata Fermentata 40g Fructus Hordei Germinatus 40g Radix Astragali 60g
Endothelium Corneum Gigeriae Galli 20g sucrose 910g
Make 1000g altogether
Preparation method:
(1) get Radix Codonopsis, Poria, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Pericarpium Citri Reticulatae, Fructus Crataegi, Massa Medicata Fermentata, Fructus Hordei Germinatus, the Radix Astragali, Endothelium Corneum Gigeriae Galli, be ground into coarse powder, add 12 times of water gagings and decocted 2 hours, decocting liquid filters; Medicinal residues add 10 times of water gagings to be fried in shallow oil 1.5 hours, and decocting liquid filters; Medicinal residues add 10 times of water gagings again and decocted 1 hour, and decocting liquid filters, and merging filtrate is evaporated to relative density and is 1.25 clear paste under 60 ℃ of conditions, standby;
(2) get above-mentioned clear paste, add sucrose, mix homogeneously is made granule, drying, and granulate, the magnesium stearate of adding 0.4%, packing, packing, check, promptly.
Embodiment 3
Prescription is formed:
Radix Codonopsis 60g Poria 40g Rhizoma Atractylodis Macrocephalae 40g
Rhizoma Dioscoreae 20g Pericarpium Citri Reticulatae 20g Fructus Crataegi 20g
Massa Medicata Fermentata 20g Fructus Hordei Germinatus 20g Radix Astragali 30g
Endothelium Corneum Gigeriae Galli 10g sucrose 420g citric acid 10g
Make 1000 altogether
Preparation method:
(1) get Radix Codonopsis, Poria, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Pericarpium Citri Reticulatae, Fructus Crataegi, Massa Medicata Fermentata, Fructus Hordei Germinatus, the Radix Astragali, Endothelium Corneum Gigeriae Galli, be ground into coarse powder, add 12 times of water gagings and decocted 2 hours, decocting liquid filters; Medicinal residues add 10 times of water gagings to be fried in shallow oil 1.5 hours, and decocting liquid filters; Medicinal residues add 10 times of water gagings again and decocted 1 hour, and decocting liquid filters, and merging filtrate is evaporated to relative density and is 1.25 clear paste under 60 ℃ of conditions, standby;
(2) get above-mentioned clear paste, add sucrose, citric acid, mix homogeneously is made granule, drying, and granulate, tabletting, packing, check, promptly.
Claims (4)
1, a kind of pharmaceutical composition for the treatment of infantile anorexia is characterized in that this pharmaceutical composition is to be made by the Chinese crude drug of following weight proportioning:
Radix Codonopsis 10～50 weight portion Poria 5～40 weight portions
The Rhizoma Atractylodis Macrocephalae 5～40 weight portion Rhizoma Dioscoreaes 5～30 weight portions
Pericarpium Citri Reticulatae 5～30 weight portion Fructus Crataegis 5～30 weight portions
Massa Medicata Fermentata 5～20 weight portion Fructus Hordei Germinatus 5～20 weight portions
The Radix Astragali 5～20 weight portion Endothelium Corneum Gigeriae Galli 3～10 weight portions.
2, a kind of pharmaceutical composition for the treatment of infantile anorexia as claimed in claim 1 is characterized in that this pharmaceutical composition is to be made by the Chinese crude drug of following weight proportioning:
Radix Codonopsis 30 weight portion Poria 20 weight portions
The Rhizoma Atractylodis Macrocephalae 20 weight portion Rhizoma Dioscoreaes 10 weight portions
Pericarpium Citri Reticulatae 10 weight portion Fructus Crataegis 10 weight portions
Massa Medicata Fermentata 10 weight portion Fructus Hordei Germinatus 10 weight portions
The Radix Astragali 15 weight portion Endothelium Corneum Gigeriae Galli 5 weight portions.
3, a kind of pharmaceutical composition for the treatment of infantile anorexia as claimed in claim 1 or 2 can be processed into oral liquid, syrup, granule, tablet, capsule, the arbitrary dosage form of chewable tablet.
4, the preparation of drug combination method of treatment infantile anorexia as claimed in claim 1 or 2 is as follows:
(1) gets Radix Codonopsis, Poria, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Pericarpium Citri Reticulatae, Fructus Crataegi, Massa Medicata Fermentata, Fructus Hordei Germinatus, the Radix Astragali, Endothelium Corneum Gigeriae Galli, be ground into coarse powder, decoct 2～3 times with 8～12 times of water gagings, each 1～3 hour, decocting liquid filters, and is concentrated into relative density and is 1.10～1.30 clear paste, and is standby;
(2) get above-mentioned clear paste, formulation method adds the suitable formulations adjuvant routinely, molding, and packing, check, promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101058381A CN101274077A (en) | 2008-05-04 | 2008-05-04 | Medicament composition for curing children's anorexia and preparation thereof |
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| CNA2008101058381A CN101274077A (en) | 2008-05-04 | 2008-05-04 | Medicament composition for curing children's anorexia and preparation thereof |
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| CNA2008101058381A Pending CN101274077A (en) | 2008-05-04 | 2008-05-04 | Medicament composition for curing children's anorexia and preparation thereof |
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Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102172389A (en) * | 2011-01-12 | 2011-09-07 | 涂传荣 | Chinese medicinal preparation having functions of promoting digestion and improving growth and development |
| CN102423435A (en) * | 2011-12-12 | 2012-04-25 | 钱家美 | Chinese medicine for treating infantile malnutrition and preparation method thereof |
| CN102657799A (en) * | 2012-05-23 | 2012-09-12 | 天津药业集团新郑股份有限公司 | External application for treatment of infantile anorexia and preparation method thereof |
| CN102743655A (en) * | 2012-07-13 | 2012-10-24 | 朱秀平 | Traditional Chinese medicine for treating infantile anorexia |
| CN103071136A (en) * | 2013-02-01 | 2013-05-01 | 冯孝义 | Traditional Chinese medicine health care product capable of regulating yin and yang balance of human bodies and preparation method of traditional Chinese medicine health care product |
| CN103495080A (en) * | 2013-10-16 | 2014-01-08 | 刘运波 | Traditional Chinese medicine for treating infantile anorexia |
| CN103656452A (en) * | 2013-12-11 | 2014-03-26 | 青岛中科菲力工程技术研发有限公司 | Traditional Chinese medicine powder for treating children anorexia |
| CN104001098A (en) * | 2014-05-30 | 2014-08-27 | 马永才 | Traditional Chinese medicine for treating infant anorexia |
| CN104042914A (en) * | 2014-06-01 | 2014-09-17 | 王纪红 | Acupuncture point patch preparation for treating child anorexia and nursing method |
| CN104623200A (en) * | 2015-02-12 | 2015-05-20 | 苏州市天灵中药饮片有限公司 | Traditional Chinese medicine composition for treating infantile anorexia and preparation method thereof |
| CN104689043A (en) * | 2015-02-02 | 2015-06-10 | 梁佳颖 | Traditional Chinese medicine oral decoction for treatment of infantile anorexia |
| CN104784648A (en) * | 2015-05-14 | 2015-07-22 | 孔凡群 | Traditional Chinese medicine preparation for anorexia and preparation method of traditional Chinese medicine preparation |
| CN105920508A (en) * | 2016-07-07 | 2016-09-07 | 合肥诺邦生物科技有限公司 | Production method of traditional Chinese medicine oral liquid with effects of invigorating stomach and promoting digestion |
| CN105998526A (en) * | 2016-06-24 | 2016-10-12 | 贵州盛世保康茶开发有限公司 | Chewable tablets for mainly treating anorexianervosa |
| CN106266423A (en) * | 2015-06-12 | 2017-01-04 | 陈盼盼 | A kind of formula controlling old people's appetite difference |
| CN108938968A (en) * | 2018-10-10 | 2018-12-07 | 裘伟莉 | A kind of Chinese medicine composition and preparation method thereof |
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2008
- 2008-05-04 CN CNA2008101058381A patent/CN101274077A/en active Pending
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| CN102172389B (en) * | 2011-01-12 | 2016-06-29 | 鲁国 | A kind of Chinese medicine preparation that there is facilitating digestion and improve growth promoter effect |
| CN102172389A (en) * | 2011-01-12 | 2011-09-07 | 涂传荣 | Chinese medicinal preparation having functions of promoting digestion and improving growth and development |
| CN102423435A (en) * | 2011-12-12 | 2012-04-25 | 钱家美 | Chinese medicine for treating infantile malnutrition and preparation method thereof |
| CN102423435B (en) * | 2011-12-12 | 2013-05-01 | 钱家美 | Chinese medicine for treating infantile malnutrition and preparation method thereof |
| CN102657799B (en) * | 2012-05-23 | 2014-02-12 | 天津药业集团新郑股份有限公司 | External application for treatment of infantile anorexia and preparation method thereof |
| CN102657799A (en) * | 2012-05-23 | 2012-09-12 | 天津药业集团新郑股份有限公司 | External application for treatment of infantile anorexia and preparation method thereof |
| CN102743655A (en) * | 2012-07-13 | 2012-10-24 | 朱秀平 | Traditional Chinese medicine for treating infantile anorexia |
| CN102743655B (en) * | 2012-07-13 | 2013-08-21 | 朱秀平 | Traditional Chinese medicine for treating infantile anorexia |
| CN103071136B (en) * | 2013-02-01 | 2014-07-23 | 冯孝义 | Traditional Chinese medicine health care product capable of regulating yin and yang balance of human bodies and preparation method of traditional Chinese medicine health care product |
| CN103071136A (en) * | 2013-02-01 | 2013-05-01 | 冯孝义 | Traditional Chinese medicine health care product capable of regulating yin and yang balance of human bodies and preparation method of traditional Chinese medicine health care product |
| CN103495080A (en) * | 2013-10-16 | 2014-01-08 | 刘运波 | Traditional Chinese medicine for treating infantile anorexia |
| CN103495080B (en) * | 2013-10-16 | 2015-03-18 | 刘运波 | Traditional Chinese medicine for treating infantile anorexia |
| CN103656452A (en) * | 2013-12-11 | 2014-03-26 | 青岛中科菲力工程技术研发有限公司 | Traditional Chinese medicine powder for treating children anorexia |
| CN104001098A (en) * | 2014-05-30 | 2014-08-27 | 马永才 | Traditional Chinese medicine for treating infant anorexia |
| CN104042914A (en) * | 2014-06-01 | 2014-09-17 | 王纪红 | Acupuncture point patch preparation for treating child anorexia and nursing method |
| CN104689043A (en) * | 2015-02-02 | 2015-06-10 | 梁佳颖 | Traditional Chinese medicine oral decoction for treatment of infantile anorexia |
| CN104689043B (en) * | 2015-02-02 | 2018-02-27 | 夏顺刚 | A kind of Chinese herbal oral decoction for treating children anorexia |
| CN104623200A (en) * | 2015-02-12 | 2015-05-20 | 苏州市天灵中药饮片有限公司 | Traditional Chinese medicine composition for treating infantile anorexia and preparation method thereof |
| CN104784648A (en) * | 2015-05-14 | 2015-07-22 | 孔凡群 | Traditional Chinese medicine preparation for anorexia and preparation method of traditional Chinese medicine preparation |
| CN106266423A (en) * | 2015-06-12 | 2017-01-04 | 陈盼盼 | A kind of formula controlling old people's appetite difference |
| CN105998526A (en) * | 2016-06-24 | 2016-10-12 | 贵州盛世保康茶开发有限公司 | Chewable tablets for mainly treating anorexianervosa |
| CN105920508A (en) * | 2016-07-07 | 2016-09-07 | 合肥诺邦生物科技有限公司 | Production method of traditional Chinese medicine oral liquid with effects of invigorating stomach and promoting digestion |
| CN108938968A (en) * | 2018-10-10 | 2018-12-07 | 裘伟莉 | A kind of Chinese medicine composition and preparation method thereof |
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Open date: 20081001 |