CN103386074B - Traditional Chinese medicinal composition for treating infantile diarrhea and preparation method thereof - Google Patents
Traditional Chinese medicinal composition for treating infantile diarrhea and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicinal composition for treating infantile diarrhea and a preparation method thereof. The composition comprises the following main raw materials: poria, bighead atractylodes rhizome, fried medicated leaven, scorched hawthorn fruit, malt, yam, lotus seed, pomegranate bark, coix seed, dried tangerine peel, fructus amomi, roasted liquorice, chicken gizzard-membrane and powdered sugar. The traditional Chinese medicinal composition can be used for effectively relieving the symptoms of collywobbles, dry mouth and oliguria caused by diarrhea, has an excellent effect of curing diarrhea, has a good effect on treating infantile diarrhea, and is a safe and effective traditional Chinese medicinal composition for treating infantile diarrhea without side effects. Local common medicinal materials are selected for the composition, and the price of the composition is low, so that the economical burden of a patient can be reduced.
Description
Technical field
The invention discloses a kind of Chinese medicine composition, especially a kind of Chinese medicine composition for the treatment of infantile diarrhea and preparation method thereof.The invention belongs to traditional Chinese medicine field.
Background technology
Infantile diarrhea is one of common and multiple disease, general multiple summer, and autumn is with gentleness, stagnant, and intestinal infection is main.Infantile acute diarrhea is caused by many reasons, but substantially fills pass with wet, moreover children's's internal organs are tender and lovely, the spleen tending to insufficiency usually, once internal damage caused by infantile dyspepsia, affection of exogenous wind-cold, evil, the impairing the spleen and stomach of summer-heat, makes dysfunction of spleen and stomach, can not digest breast food.Make clear QI being mixed up with turbid QI, bet large intestine, and for having loose bowels.
Therapeutic Principle at present to infantile diarrhea, with invigorating the spleen and regulating the stomach, dampness removing, helps digestion, intestinal stasis relieving, infection is main.The medicine of present clinical treatment infantile diarrhea is more, there are Chinese patent medicine and Western medicine, but they are limited to infantile diarrhea therapeutic effect, can not at very short time internal therapy infantile diarrhea, the health of child is sustained damage deterioration, a kind of treat the Chinese medicine composition (Authorization Notice No. is: CN100358549C) of diarrhoeal diseases patent discloses a kind of Chinese medicine formula: it has Rhizoma Coptidis, the Radix Astragali, the Radix Paeoniae Alba, Herba Pogostemonis, Folium Psidii Guajavae, Poria to be that raw material is made.It has effect of heat-clearing and toxic substances removing, scorching antidiarrheal, but its course for the treatment of is long, and general needs three talentes can cure, and cure rate is also lower.
Summary of the invention
For the present situation of existing treatment infantile diarrhea curative effect deficiency, an object of the present invention is to provide a kind of Chinese medicine composition for the treatment of infantile diarrhea, has feature evident in efficacy, and the present invention adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned Chinese medicine composition.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Treat a Chinese medicine composition for infantile diarrhea, take off the primary raw material stating weight proportion and be prepared from: Poria 2-8 part, Rhizoma Atractylodis Macrocephalae 2-8 part, Massa Medicata Fermentata preparata 4-10 part, Fructus Crataegi (parched to brown) (looking into) 4-10 part, Fructus Hordei Germinatus 4-10 part, Rhizoma Dioscoreae 3-9 part, Semen Nelumbinis 2-8 part, Pericarpium Granati 4-10 part is (preferred, Pericarpium Granati 4.5-9.5 part), Semen Coicis 2-8 part, Pericarpium Citri Reticulatae 1-7 part, Fructus Amomi 1-7 part, Radix Glycyrrhizae Preparata 1-5 part, Endothelium Corneum Gigeriae Galli 2-8 part, Icing Sugar 2-8 part.
Treat a Chinese medicine composition for infantile diarrhea, preferred scheme, take off the primary raw material stating weight proportion and be prepared from: Poria 3-7 part, Rhizoma Atractylodis Macrocephalae 3-7 part, Massa Medicata Fermentata preparata 5-9 part, Fructus Crataegi (parched to brown) (looking into) 5-9 part, Fructus Hordei Germinatus 5-9 part, Rhizoma Dioscoreae 4-8 part, Semen Nelumbinis 3-7 part, Pericarpium Granati 5-9 part, Semen Coicis 3-7 part, Pericarpium Citri Reticulatae 2-6 part, Fructus Amomi 2-6 part, Radix Glycyrrhizae Preparata 1.5-4.5 part, Endothelium Corneum Gigeriae Galli 3-7 part, Icing Sugar 3-7 part.
Treat a Chinese medicine composition for infantile diarrhea, good scheme, take off the primary raw material stating weight proportion and be prepared from: Poria 4-6 part, Rhizoma Atractylodis Macrocephalae 4-6 part, Massa Medicata Fermentata preparata 6-8 part, Fructus Crataegi (parched to brown) (looking into) 6-8 part, Fructus Hordei Germinatus 6-8 part, Rhizoma Dioscoreae 5-7 part, Semen Nelumbinis 4-6 part, Pericarpium Granati 6-8 part, Semen Coicis 4-6 part, Pericarpium Citri Reticulatae 3-5 part, Fructus Amomi 3-5 part, Radix Glycyrrhizae Preparata 2-4 part, Endothelium Corneum Gigeriae Galli 4-6 part, Icing Sugar 4-6 part.
Treat a Chinese medicine composition for infantile diarrhea, better preferred scheme, take off the primary raw material stating weight proportion and be prepared from: 5 parts, Poria, the Rhizoma Atractylodis Macrocephalae 5 parts, Massa Medicata Fermentata preparata 7 parts, Fructus Crataegi (parched to brown) (looking into) 7 parts, 7 parts, Fructus Hordei Germinatus, Rhizoma Dioscoreae 6 parts, 5 parts, Semen Nelumbinis, Pericarpium Granati 7 parts, Semen Coicis 5 parts, Pericarpium Citri Reticulatae 4 parts, Fructus Amomi 4 parts, Radix Glycyrrhizae Preparata 3 parts, Endothelium Corneum Gigeriae Galli 5 parts, Icing Sugar 5.
Treat a preparation method for the Chinese medicine composition of infantile diarrhea, be prepared from primarily of following step:
1. Rhizoma Dioscoreae is worn into fine powder for subsequent use;
2. by Poria, the Rhizoma Atractylodis Macrocephalae, Fructus Hordei Germinatus, Semen Nelumbinis, Pericarpium Granati, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata, Endothelium Corneum Gigeriae Galli decocts with water 2 times, 2.0 hours first times, second time 1.5 hours, and filtrate merging decocts 1 hour again, leaves standstill 20-30 hour, again filters, obtain filtrate for subsequent use;
3. by step 1. in gained Rhizoma Dioscoreae powder add in the filtrate of step 2. gained, Rhizoma Dioscoreae powder consumption be the 0.5-1.5 of filtrate quality doubly, abundant mix homogeneously, leaves standstill cold preservation 30 hours, filters, and after filtrate is reclaimed, then continues to be concentrated into thick paste;
4. get appropriate Icing Sugar and dry 1-2 hour in 60 DEG C, be placed in appropriate vessel, add step 3. middle gained thick paste stirring and evenly mixing, being modulated into soft durometer is that hands is pinched agglomerating, the soft material that light pressure is then loose, and 10-14 mesh sieve crossed by soft material, makes wet granular;
5. wet granular bake drying step 4. made, baking temperature is 60 DEG C-80 DEG C, and after cooling, sealing is stand-by.
Described preparation method, preferred scheme is, 2. step leaves standstill 23-28 hour, and (being preferably 25 hours) is filtering.
Described preparation method, preferred scheme is, step 3. Rhizoma Dioscoreae powder consumption is that the 0.7-1.3 of filtrate quality doubly (is preferably 1.0 times).
Described preparation method, preferred scheme is, 4. step is got appropriate Icing Sugar and dried 1.2-1.8 hour (being preferably 1.5 hours) in 60 DEG C, and 10-14 mesh sieve (being preferably 12 mesh sieves) crossed by soft material.
Described preparation method, preferred scheme is, step 5. baking temperature is 65 DEG C-75 DEG C (being preferably 70 DEG C).
Instructions of taking: every day 4 times, warm water or brown sugar water take on an empty stomach, 6 hours once, take medicine latter 20 minutes disease amelioration, generally take 4 times and all cure, intestinal lavage patient adds one day, general infant is each 1-3 gram within 6 months, 6-12 month 3-4 gram, three years old always each 3-5 gram, within more than three years old, infant can increase in proportion.
This Chinese medicine composition, to infantile diarrhea Be very effective, has effect of pain relieving, antidiarrheal.The local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
The pharmacological effect of each crude drug is respectively:
Poria: sweet in the mouth, light, property are put down.GUIXIN, lung, spleen, kidney channel.Promoting diuresis to eliminate damp pathogen, spleen invigorating.
The Rhizoma Atractylodis Macrocephalae: sweet in the mouth, hardship, warm in nature.Return spleen, stomach warp.The spleen strengthening and damp drying, excessive gas hemopoietic, dampness diuretic.
Massa Medicata Fermentata preparata: sweet in the mouth, pungent, warm in nature.Return spleen, stomach warp.Promoting digestion and removing stagnation, invigorating the spleen and regulating the stomach, induces sweat.Cure mainly flu dyspepsia, epigastric distension and distress, dyspepsia, diarrhoea.
Fructus Crataegi (parched to brown): different name: Qiu, Qiu, Mus look into, Yang Qiu, red pawl real, Tang Qiu, red Chinese date, Fructus Pyri Pashiae fruit, Ziziphi Spinosae, nasal mucus group.Nature and flavor: acid is sweet, tepor.Gui Jing: enter spleen, stomach, Liver Channel.Function cures mainly: help digestion long-pending, dissipating blood stasis blood, expelling tenia.Control meat Ji ， mass in the abdomen, phlegm retention, feeling of fullness, acid regurgitation, dysentery, hemorrhoidal hamorrhage, lumbago, hernia after-pains in puerperal, lochiorrhea, children's's breast food is stagnated.Promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, stomach alkane distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain, hyperlipidemia.
Fructus Hordei Germinatus: different name: Fructus Hordei Vulgaris tiller, wheat tiller, Fructus Hordei Vulgaris hair, Fructus Hordei Germinatus.Nature and flavor: sweet, tepor.Gui Jing enters spleen, stomach warp.Help digestion, and in, the therapeutic method to keep the adverse QI flowing downwards.Control food stagnation not disappear, distension and fullness in the abdomen, inappetence, vomiting is had loose bowels, and mammary swelling does not disappear.Rhizoma Dioscoreae: sweet in the mouth, property are flat.Return spleen, stomach, lung meridian.Invigorating the spleen and regulating the stomach, lung benefiting yin nourishing.
Semen Nelumbinis: different name, Rhizoma Nelumbinis reality, Shui Zhidan, Semen Nelumbinis, Semen Nelumbinis, seedpod of the lotus.Nature and flavor are sweet, puckery, flat.Gui Jing: enter the heart, spleen, kidney channel.Function cures mainly: nourish heart, kidney tonifying, spleen reinforcing.Astringing intestine to stop diarrhea.Pericarpium Granati: sour in the mouth, puckery, warm in nature.Return large intestine channel.Relieving diarrhea with astringents, killing parasites for relieving itching.
Semen Coicis: different name: separate calabash shell serving as a dipper, a reality, Jiangxi rice, sense rice, heart of a lotus seed pearl, jobstears, careless bead, the Fructus Sapindi Mukouossi, Jiangxi pearl, pearl, glutinous rehmannia reality, Semen Coicis, Semen Coicis must be carried.Nature and flavor: sweet light, cool, sweet in the mouth, is slightly cold, property is put down.Gui Jing: enter spleen, lung, kidney channel.Function cures mainly: spleen invigorating, tonifying the lung, heat clearing away, dampness removing.Control and have loose bowels, arthralgia chiefly caused by damp pathogen, the contracture of muscle arteries and veins, joint stuffiness, edema, beriberi, consumptive lung disease, lung abscess, acute appendicitis, stranguria with turbid discharge, leucorrhea.Pericarpium Citri Reticulatae: another name: red Fructus Citri tangerinae, Radix Campylotropis Hirtella (Herba Myrsines Africanae), river Fructus Citri tangerinae.Nature and flavor: warm in nature, bitter in the mouth, pungent.Function cures mainly: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough ant phlegm.Fructus Amomi: different name: contracting Fructus Amomi, contracting sand honey, Amomum xanthioides.Nature and flavor: pungent, temperature.Gui Jing: enter spleen, stomach warp.Function cures mainly: during circulation of qi promoting is adjusted, stomach function regulating, is amusing.Control stomachache painful abdominal mass swollen, anorexia dyspepsia, dysphagic vomiting, diarrhea due to cold pathogen cold-dysentery, pregnant fetal movement.Radix Glycyrrhizae Preparata: nature and flavor: sweet, put down, process sweet, warm.Gui Jing: GUIXIN, lung, spleen, stomach warp.Effect and effect: spleen reinforcing stomach function regulating, Yiqi and vein recovery.For weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse.
Endothelium Corneum Gigeriae Galli: sweet in the mouth, property is put down.Return spleen, stomach, urinary bladder channel.Help digestion activating the spleen, dissipating blood stasis fossil.
Icing Sugar: taste is sweet.For the adjuvant of above-mentioned Chinese medicine composition.
Chinese medicine composition of the present invention debates the principle of disease treatment based on Chinese medicine.The medical material selected is divided into powder medicine for oral administration, has fabulous therapeutical effect to infantile diarrhea.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1treat a Chinese medicine composition for infantile diarrhea, get following traditional Chinese medicine raw medicine: 2 grams, Poria, the Rhizoma Atractylodis Macrocephalae 2 grams, Massa Medicata Fermentata preparata 4 grams, Fructus Crataegi (parched to brown) (looking into) 4 grams, 4 grams, Fructus Hordei Germinatus, Rhizoma Dioscoreae 3 grams, 2 grams, Semen Nelumbinis, Pericarpium Granati 4 grams, Semen Coicis 2 grams, Pericarpium Citri Reticulatae 1 gram, Fructus Amomi 1 gram, Radix Glycyrrhizae Preparata 1 gram, Endothelium Corneum Gigeriae Galli 2 grams, Icing Sugar 2 grams.
The preparation method of above-mentioned Chinese medicine composition, step is:
1. Rhizoma Dioscoreae is worn into fine powder for subsequent use;
2. by Poria, the Rhizoma Atractylodis Macrocephalae, Fructus Hordei Germinatus, Semen Nelumbinis, Pericarpium Granati, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata, Endothelium Corneum Gigeriae Galli decocts with water 2 times, 2.0 hours first times, second time 1.5 hours, and filtrate merging decocts 1 hour again, leaves standstill 20-30 hour, again filters, obtain filtrate for subsequent use;
3. by step 1. in gained Rhizoma Dioscoreae powder add in the filtrate of step 2. gained, Rhizoma Dioscoreae powder consumption be the 0.5-1.5 of filtrate quality doubly, abundant mix homogeneously, leaves standstill cold preservation 30 hours, filters, and after filtrate is reclaimed, then continues to be concentrated into thick paste;
4. get appropriate Icing Sugar and dry 1-2 hour in 60 DEG C, be placed in appropriate vessel, add step 3. middle gained thick paste stirring and evenly mixing, being modulated into soft durometer is that hands is pinched agglomerating, the soft material that light pressure is then loose, and 10-14 mesh sieve crossed by soft material, makes wet granular;
5. wet granular bake drying step 4. made, baking temperature is 60 DEG C-80 DEG C, and after cooling, sealing is stand-by.
Instructions of taking: every day 4 times, warm water or brown sugar water take on an empty stomach, 6 hours once, to take medicine latter 20 minutes disease amelioration, generally take 4 times and all cure, intestinal lavage patient adds and pays one day, general infant within 6 months each 1 gram, 6 months 3 grams, three years old always each 3 grams, within more than three years old, infant can increase in proportion.Adult is each serving a money.
embodiment 2treat a Chinese medicine composition for infantile diarrhea, get following traditional Chinese medicine raw medicine: 8 grams, Poria, the Rhizoma Atractylodis Macrocephalae 8 grams, Massa Medicata Fermentata preparata 10 grams, Fructus Crataegi (parched to brown) (looking into) 10 grams, 10 grams, Fructus Hordei Germinatus, Rhizoma Dioscoreae 9 grams, 8 grams, Semen Nelumbinis, Pericarpium Granati 10 grams, Semen Coicis 8 grams, Pericarpium Citri Reticulatae 7 grams, Fructus Amomi 7 grams, Radix Glycyrrhizae Preparata 5 grams, Endothelium Corneum Gigeriae Galli 8 grams, Icing Sugar 8 grams.
The preparation method of above-mentioned Chinese medicine composition, step is:
1. Rhizoma Dioscoreae is worn into fine powder for subsequent use;
2. by Poria, the Rhizoma Atractylodis Macrocephalae, Fructus Hordei Germinatus, Semen Nelumbinis, Pericarpium Granati, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata, Endothelium Corneum Gigeriae Galli decocts with water 2 times, 2.0 hours first times, second time 1.5 hours, and filtrate merging decocts 1 hour again, leaves standstill 20-30 hour, again filters, obtain filtrate for subsequent use;
3. by step 1. in gained Rhizoma Dioscoreae powder add in the filtrate of step 2. gained, Rhizoma Dioscoreae powder consumption be the 0.5-1.5 of filtrate quality doubly, abundant mix homogeneously, leaves standstill cold preservation 30 hours, filters, and after filtrate is reclaimed, then continues to be concentrated into thick paste;
4. get appropriate Icing Sugar and dry 1-2 hour in 60 DEG C, be placed in appropriate vessel, add step 3. middle gained thick paste stirring and evenly mixing, being modulated into soft durometer is that hands is pinched agglomerating, the soft material that light pressure is then loose, and 10-14 mesh sieve crossed by soft material, makes wet granular;
5. wet granular bake drying step 4. made, baking temperature is 60 DEG C-80 DEG C, and after cooling, sealing is stand-by.
Instructions of taking: every day 4 times, warm water or brown sugar water take on an empty stomach, 6 hours once, to take medicine latter 20 minutes disease amelioration, generally take 4 times and all cure, intestinal lavage patient adds and pays one day, general infant within 6 months each 3 grams, 12 months 4 grams, three years old always each 5 grams, within more than three years old, infant can increase in proportion.Adult is each serving a money.
model case 1:male, king xx, 15 months large.Autumn falls ill, and suffer from diarrhoea one month, and it is all invalid that transfusion is had an injection, diarrhoea every day 7-8 time, and diarrhoea amount is many at every turn, and defecate for yellow, rare watery stool, urine volume is few, with vomiting.Take this medicine four times, within six hours, take once, recovery from illness in a day.
embodiment 3:treat a Chinese medicine composition for infantile diarrhea, get following traditional Chinese medicine raw medicine: 3 grams, Poria, the Rhizoma Atractylodis Macrocephalae 3 grams, Massa Medicata Fermentata preparata 5 grams, Fructus Crataegi (parched to brown) (looking into) 5 grams, 5 grams, Fructus Hordei Germinatus, Rhizoma Dioscoreae 4 grams, 3 grams, Semen Nelumbinis, Pericarpium Granati 5 grams, Semen Coicis 3 grams, Pericarpium Citri Reticulatae 2 grams, Fructus Amomi 2 grams, Radix Glycyrrhizae Preparata 1.5 grams, Endothelium Corneum Gigeriae Galli 3 grams, Icing Sugar 3 grams.
The preparation method of above-mentioned Chinese medicine composition, step is:
1. Rhizoma Dioscoreae is worn into fine powder for subsequent use;
2. by Poria, the Rhizoma Atractylodis Macrocephalae, Fructus Hordei Germinatus, Semen Nelumbinis, Pericarpium Granati, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata, Endothelium Corneum Gigeriae Galli decocts with water 2 times, 2.0 hours first times, second time 1.5 hours, and filtrate merging decocts 1 hour again, leaves standstill 20-30 hour, again filters, obtain filtrate for subsequent use;
3. by step 1. in gained Rhizoma Dioscoreae powder add in the filtrate of step 2. gained, Rhizoma Dioscoreae powder consumption be the 0.5-1.5 of filtrate quality doubly, abundant mix homogeneously, leaves standstill cold preservation 30 hours, filters, and after filtrate is reclaimed, then continues to be concentrated into thick paste;
4. get appropriate Icing Sugar and dry 1-2 hour in 60 DEG C, be placed in appropriate vessel, add step 3. middle gained thick paste stirring and evenly mixing, being modulated into soft durometer is that hands is pinched agglomerating, the soft material that light pressure is then loose, and 10-14 mesh sieve crossed by soft material, makes wet granular;
5. wet granular bake drying step 4. made, baking temperature is 60 DEG C-80 DEG C, and after cooling, sealing is stand-by.
Instructions of taking: every day 4 times, warm water or brown sugar water take on an empty stomach, 6 hours once, to take medicine latter 20 minutes disease amelioration, generally take 4 times and all cure, intestinal lavage patient adds and pays one day, general infant within 6 months each 1 gram, 6 months 3 grams, three years old always each 3 grams, within more than three years old, infant can increase in proportion.Adult is each serving a money.
model case 2:king XX, women, 10 months large.Suffer from diarrhoea 7 days, stool is in green, and defecate 5-6 time on the one, transfusion is had an injection, and intestinal lavage is all invalid.Take this Chinese medicine to fully recover one day after.
embodiment 4treat a Chinese medicine composition for infantile diarrhea, get following traditional Chinese medicine raw medicine: 7 grams, Poria, the Rhizoma Atractylodis Macrocephalae 7 grams, Massa Medicata Fermentata preparata 9 grams, Fructus Crataegi (parched to brown) (looking into) 9 grams, 9 grams, Fructus Hordei Germinatus, Rhizoma Dioscoreae 8 grams, 7 grams, Semen Nelumbinis, Pericarpium Granati 9 grams, Semen Coicis 7 grams, Pericarpium Citri Reticulatae 6 grams, Fructus Amomi 6 grams, Radix Glycyrrhizae Preparata 4.5 grams, Endothelium Corneum Gigeriae Galli 7 grams, Icing Sugar 7 grams.
The preparation method of above-mentioned Chinese medicine composition, step is:
1. Rhizoma Dioscoreae is worn into fine powder for subsequent use;
2. by Poria, the Rhizoma Atractylodis Macrocephalae, Fructus Hordei Germinatus, Semen Nelumbinis, Pericarpium Granati, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata, Endothelium Corneum Gigeriae Galli decocts with water 2 times, 2.0 hours first times, second time 1.5 hours, and filtrate merging decocts 1 hour again, leaves standstill 20-30 hour, again filters, obtain filtrate for subsequent use;
3. by step 1. in gained Rhizoma Dioscoreae powder add in the filtrate of step 2. gained, Rhizoma Dioscoreae powder consumption be the 0.5-1.5 of filtrate quality doubly, abundant mix homogeneously, leaves standstill cold preservation 30 hours, filters, and after filtrate is reclaimed, then continues to be concentrated into thick paste;
4. get appropriate Icing Sugar and dry 1-2 hour in 60 DEG C, be placed in appropriate vessel, add step 3. middle gained thick paste stirring and evenly mixing, being modulated into soft durometer is that hands is pinched agglomerating, the soft material that light pressure is then loose, and 10-14 mesh sieve crossed by soft material, makes wet granular;
5. wet granular bake drying step 4. made, baking temperature is 60 DEG C-80 DEG C, and after cooling, sealing is stand-by.
Instructions of taking: every day 4 times, warm water or brown sugar water take on an empty stomach, 6 hours once, to take medicine latter 20 minutes disease amelioration, generally take 4 times and all cure, intestinal lavage patient adds and pays one day, general infant within 6 months each 3 grams, 12 months 4 grams, three years old always each 5 grams, within more than three years old, infant can increase in proportion.Adult is each serving a money.
model case 3:lu XX
,male, six months large, suffers from diarrhoea 3 days, body temperature 38 degree, oliguria.Stool is in green, and stool one day more than 10 times, takes medicine and cure for one day.
embodiment 5:treat a Chinese medicine composition for infantile diarrhea, get following traditional Chinese medicine raw medicine: 5 grams, Poria, the Rhizoma Atractylodis Macrocephalae 5 grams, Massa Medicata Fermentata preparata 7 grams, Fructus Crataegi (parched to brown) (looking into) 7 grams, 7 grams, Fructus Hordei Germinatus, Rhizoma Dioscoreae 6 grams, 5 grams, Semen Nelumbinis, Pericarpium Granati 7 grams, Semen Coicis 5 grams, Pericarpium Citri Reticulatae 4 grams, Fructus Amomi 4 grams, Radix Glycyrrhizae Preparata 3 grams, Endothelium Corneum Gigeriae Galli 5 grams, Icing Sugar 5 grams.
The preparation method of above-mentioned Chinese medicine composition, step is:
1. Rhizoma Dioscoreae is worn into fine powder for subsequent use;
2. by Poria, the Rhizoma Atractylodis Macrocephalae, Fructus Hordei Germinatus, Semen Nelumbinis, Pericarpium Granati, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata, Endothelium Corneum Gigeriae Galli decocts with water 2 times, 2.0 hours first times, second time 1.5 hours, and filtrate merging decocts 1 hour again, leaves standstill 20-30 hour, again filters, obtain filtrate for subsequent use;
3. by step 1. in gained Rhizoma Dioscoreae powder add in the filtrate of step 2. gained, Rhizoma Dioscoreae powder consumption be the 0.5-1.5 of filtrate quality doubly, abundant mix homogeneously, leaves standstill cold preservation 30 hours, filters, and after filtrate is reclaimed, then continues to be concentrated into thick paste;
4. get appropriate Icing Sugar and dry 1-2 hour in 60 DEG C, be placed in appropriate vessel, add step 3. middle gained thick paste stirring and evenly mixing, being modulated into soft durometer is that hands is pinched agglomerating, the soft material that light pressure is then loose, and 10-14 mesh sieve crossed by soft material, makes wet granular;
5. wet granular bake drying step 4. made, baking temperature is 60 DEG C-80 DEG C, and after cooling, sealing is stand-by.
Instructions of taking: every day 4 times, warm water or brown sugar water take on an empty stomach, 6 hours once, to take medicine latter 20 minutes disease amelioration, generally take 4 times and all cure, intestinal lavage patient adds and pays one day, general infant is each 1-3 gram within 6 months, 6-12 month 3-4 gram, one to three year old each 3-5 gram, within more than three years old, infant can increase in proportion.
The beneficial effect adopting technique scheme to produce is: this Chinese medicine can reach the object of rapid healing infantile diarrhea by rational formula, children's's body immunity can be increased, and it is pure Chinese medicine, dosage is few, be convenient to child take, without secondary use, curative effect is fast, within general one day, just can cure, cure rate can reach 96%.All medicines coordinate, tonify without causing stagnation.
In order to verify the effect of Chinese medicine composition of the present invention, we have extracted 150 patients and have carried out the experiment of medicine, are equally divided into two groups, often organize 75 people, experimental group and matched group, experimental group uses embodiment 5 gained Chinese medicine composition, and matched group takes the Chinese medicine of other treatment infantile diarrhea.
Inclusion criteria: through being diagnosed as infantile diarrhea patient, has infantile diarrhea clinical symptoms one or more.
Curative effect situation criterion (contrasting with the data taking 1 week): 1, cure.Drug administration 1 week, malaise symptoms disappears completely; 2, effective.Drug administration 1 week, malaise symptoms alleviates or partial disappearance; 3, invalid.Drug administration 1 week, malaise symptoms is unchanged.
We have carried out accurate statistics and mathematical analysis to experimental data.Specific experiment result is as following table:
Table 1: two groups of Clinical efficacy comparisons [example]
| Group | Case load | Cure | Effectively | Invalid | Total effective rate |
| Matched group | 75 | 2 | 28 | 45 | 40% |
| Experimental group | 75 | 62 | 10 | 3 | 96% |
Result: two groups of Clinical efficacy comparisons, matched group total effective rate is 40%; Experimental group total effective rate is that 96%, two groups of total effective rates compare and show that experimental group curative effect is better than matched group.
Chinese medicine composition of the present invention effective percentage compared with other medicine for the treatment of infantile diarrhea is high, total effective rate is 96%, higher than matched group effective percentage by 56%, successful is better than matched group, the Chinese medicine composition of this invention is cheap, also can not increase health and pecuniary burden, the present invention a kind ofly treats infantile diarrhea safety and Chinese medicine composition without any side effects.
Claims (4)
1. treat a Chinese medicine composition for infantile diarrhea, it is characterized in that: take off the crude drug stating weight proportion and be prepared from: Poria 2-8 part, Rhizoma Atractylodis Macrocephalae 2-8 part, Massa Medicata Fermentata preparata 4-10 part, Fructus Crataegi (parched to brown) 4-10 part, Fructus Hordei Germinatus 4-10 part, Rhizoma Dioscoreae 3-9 part, Semen Nelumbinis 2-8 part, Pericarpium Granati 4-10 part, Semen Coicis 2-8 part, Pericarpium Citri Reticulatae 1-7 part, Fructus Amomi 1-7 part, Radix Glycyrrhizae Preparata 1-5 part, Endothelium Corneum Gigeriae Galli 2-8 part, Icing Sugar 2-8 part.
2. the Chinese medicine composition for the treatment of infantile diarrhea according to claim 1, is characterized in that: each crude drug is as follows: Poria 3-7 part, Rhizoma Atractylodis Macrocephalae 3-7 part, Massa Medicata Fermentata preparata 5-9 part, Fructus Crataegi (parched to brown) 5-9 part, Fructus Hordei Germinatus 5-9 part, Rhizoma Dioscoreae 4-8 part, Semen Nelumbinis 3-7 part, Pericarpium Granati 5-9 part, Semen Coicis 3-7 part, Pericarpium Citri Reticulatae 2-6 part, Fructus Amomi 2-6 part, Radix Glycyrrhizae Preparata 1.5-4.5 part, Endothelium Corneum Gigeriae Galli 3-7 part, Icing Sugar 3-7 part.
3. the Chinese medicine composition for the treatment of infantile diarrhea according to claim 1, is characterized in that: each crude drug is as follows: Poria 4-6 part, Rhizoma Atractylodis Macrocephalae 4-6 part, Massa Medicata Fermentata preparata 6-8 part, Fructus Crataegi (parched to brown) 6-8 part, Fructus Hordei Germinatus 6-8 part, Rhizoma Dioscoreae 5-7 part, Semen Nelumbinis 4-6 part, Pericarpium Granati 6-8 part, Semen Coicis 4-6 part, Pericarpium Citri Reticulatae 3-5 part, Fructus Amomi 3-5 part, Radix Glycyrrhizae Preparata 2-4 part, Endothelium Corneum Gigeriae Galli 4-6 part, Icing Sugar 4-6 part.
4. the Chinese medicine composition for the treatment of infantile diarrhea according to claim 1, is characterized in that: each crude drug is as follows: 5 parts, Poria, the Rhizoma Atractylodis Macrocephalae 5 parts, Massa Medicata Fermentata preparata 7 parts, Fructus Crataegi (parched to brown) 7 parts, 7 parts, Fructus Hordei Germinatus, Rhizoma Dioscoreae 6 parts, 5 parts, Semen Nelumbinis, Pericarpium Granati 7 parts, Semen Coicis 5 parts, Pericarpium Citri Reticulatae 4 parts, Fructus Amomi 4 parts, Radix Glycyrrhizae Preparata 3 parts, Endothelium Corneum Gigeriae Galli 5 parts, Icing Sugar 5 parts.
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| CN109381632A (en) * | 2017-08-02 | 2019-02-26 | 徐定清 | A kind of medicine pill of benefit intestines stomach function regulating ball |
| CN107441440A (en) * | 2017-08-25 | 2017-12-08 | 张慧 | A kind of medicine for treating children's diarrhae and preparation method thereof |
| CN108514630A (en) * | 2018-06-24 | 2018-09-11 | 杨塬 | A kind of pharmaceutical composition for treating baby diarrhea |
| CN112535714A (en) * | 2020-12-17 | 2021-03-23 | 上海中医药大学附属曙光医院 | Novel traditional Chinese medicine composition for treating infantile diarrhea and processing method |
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