CN102423435A - Chinese medicine for treating infantile malnutrition and preparation method thereof - Google Patents
Chinese medicine for treating infantile malnutrition and preparation method thereof Download PDFInfo
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- CN102423435A CN102423435A CN2011104107818A CN201110410781A CN102423435A CN 102423435 A CN102423435 A CN 102423435A CN 2011104107818 A CN2011104107818 A CN 2011104107818A CN 201110410781 A CN201110410781 A CN 201110410781A CN 102423435 A CN102423435 A CN 102423435A
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Abstract
The invention discloses a Chinese medicine for treating infantile malnutrition and a preparation method thereof. The Chinese medicine is prepared from the following Chinese medicinal materials in part by weight: 10-40 parts of cicada slough, 10-30 parts of white atractylodes rhizome, 5-30 parts of rhizoma dioscoreae, 3-10 parts of corium stomachium galli, 5-30 parts of tangerine peel, 5-30 parts of hawthorn, 5-10 parts of colored malt, 5-10 parts of betel nut and 5-15 parts of milkvetch root. The Chinese medicine can be processed into any clinically-acceptable dosage form of oral solution, syrup, tablet, granules and chewable tablet, through the processing procedures, such as extraction, concentration, drying, and the like. The Chinese medicine has the effects of invigorating the spleen, stimulating the appetite, supplementing qi, nourishing the blood, promoting digestion, and expelling worms, and is used for treating the infantile malnutrition, evidential inappetence, dyspepsia, mental fatigue and hypodynamia, athrepsy, sallow faces, low disease resistance, and the like.
Description
Technical field
The present invention relates to a kind of Chinese medicine of treating children's infantile malnutrition symptom and preparation method thereof.
Background technology
Infantile malnutrition is a kind of child's common frdquently encountered disease, always is one of department of pediatrics four big diseases (pox, fiber crops, frightened, infantile malnutrition), belongs to digestion, absorption, malnutrition syndrome.Qian Yi points out in key to Therapeutics of Children's Diseases: " infantile malnutrition is the spleen-stomach disease all, and the institute of depletion of body fluid does also ' '.Wang Kentang " Standards of Diagnosis and Treatment " is discussed: " on the whole infantile malnutrition be disease, all crosses the food and drink food, in tame one dirty have to amass do not control, dirty after the biography, form the disease of five kinds of child malnutrition.If spleen man disease is gone, then surplus dirty all peaces; It controls careless mistake, with the passing of time the change of disease must be arranged ".
" the spleen tending to insufficiency usually " is one of the physiological characteristics in children's period; So intemperance of taking food, particular about food, have a liking for the food fragrant and sweet raw food; It is impaired to cause taste more easily, causes heat produced by dietary stagnation, consumes stomach-Yin, incoordination between the spleen and stomach, receives and transport and abnormal ascending-descending of QI, so poor appetite anorexia, abdominal distention or pain, urine occur like water from washing rice; And then then cause weakness of the spleen and stomach, and essence of water and grain can not the compress skin and is guaranteed that whole body growths needs, so emaciation and sallow complexion occurs, body development is slow, resistance against diseases weakening; Incoordination between the spleen and stomach, it is uneasy then to sleep night." the liver being liable to excess " is children's's another physiological characteristics in period, and weakness of the spleen and stomach causes the edema with the liver involved ash to be taken advantage of more easily, forms the weak liver-yang hyperactivity of spleen,
So disposition agitation, active uneasiness occur, be prone to fly into a rage, rub eyebrow and dig nose, prostrate grinding tooth.
Pediatric Clinic is often run into because of yellow complexion, is become thin, inappetence, temper is strange or feel that often the infant of abdominal distention, stomachache goes to a doctor.To the many diagnostic strengths of this doctor trained in Western medicine " slight malnutrition ", only be according to the clinical symptoms complementary medicine, promote protein adsorption like the injection anabolic hormone, replenish multiple little give birth to plain and trace element, aminoacid etc.; Improve digestive and absorptive functions also for the medicine of some polyzyme tabletses, lactasinum and so on.But, owing to cure the symptoms, not the disease, fundamentally do not improve child's digestive and absorptive functions, therefore, can not reach gratifying curative effect.
Summary of the invention
The object of the invention is to provide a kind of Chinese medicine of treating children's infantile malnutrition symptom, has spleen benefiting and stimulating the appetite, benefiting QI and nourishing blood, helps digestion, the effect of anthelmintic, is used to treat children's infantile malnutrition symptom; Card is seen inappetence, dyspepsia, spiritlessness and weakness; Become thin, the complexion jaundice, premunition is low etc.The present invention also will provide this preparation method of Chinese medicine.
In order to reach the foregoing invention purpose, the Chinese medicine of treatment children's infantile malnutrition symptom provided by the invention comprises following parts by weight of Chinese traditional medicine:
Periostracum Cicadae 10～40 weight portions
The Rhizoma Atractylodis Macrocephalae 10～30 weight portions
Rhizoma Dioscoreae 5～30 weight portions
Endothelium Corneum Gigeriae Galli 3～10 weight portions
Pericarpium Citri Reticulatae 5～30 weight portions
Fructus Crataegi 5～30 weight portions
Fructus Hordei Germinatus (parched) 5～10 weight portions
Semen Arecae 5～10 weight portions
The Radix Astragali 5 ~ 15 weight portions.
As preferably, the Chinese medicine of treatment children's infantile malnutrition symptom provided by the invention comprises following parts by weight of Chinese traditional medicine:
Periostracum Cicadae 30 weight portions
The Rhizoma Atractylodis Macrocephalae 20 weight portions
Rhizoma Dioscoreae 20 weight portions
Endothelium Corneum Gigeriae Galli 8 weight portions
Pericarpium Citri Reticulatae 10 weight portions
Fructus Crataegi 20 weight portions
Fructus Hordei Germinatus (parched) 8 weight portions
Semen Arecae 8 weight portions
The Radix Astragali 10 weight portions.
Periostracum Cicadae has the effect of air making-up and spleen enlivening, is loaded with in " book on Chinese herbal medicine converges and says ": " Periostracum Cicadae is to foster taste, and the wet dissipation eliminating impediment helps digestion except that the key medicine of painful abdominal mass, and insufficiency of the spleen strong, art can be mended it, and insufficiency of stomach is not received, and art can help it." mainly contain volatile oil component, be the treatment deficiency of spleen-QI and stomach-QI, fortuneization is unable, anorexia and loose stool, the conventional Chinese medicine material that the soft Mental fatigue of limb etc. are demonstrate,proved has the effect of strengthening body; Be equipped with QI invigorating, spleen reinforcing, the Rhizoma Atractylodis Macrocephalae that nourishes blood, Rhizoma Dioscoreae, the Radix Astragali, Pericarpium Citri Reticulatae,, and have excitor nerve, enhancing human body immunity power, regulate gastrointestinal motility, the effect of strengthening by means of tonics with the power of the invigorating the spleen and replenishing QI of enhancing Periostracum Cicadae, strengthening the spleen and nourishing the stomach; In the side Endothelium Corneum Gigeriae Galli, Fructus Crataegi, Fructus Hordei Germinatus (parched) have be good for the stomach, help digestion, the effect of eliminate indigestion, have stronger promoting digestion and removing stagnation effect, be widely used in the infantile malnutrition that rice and flour potato and meat etc. cause, but and appetite stimulator; Semen Arecae has the effect of expelling intestinal worms and removing food stagnancy, promptly arrogates to oneself the gas of capable gastrointestinal, increases enterokinesia, consumer product dredge stasis; Again multiple Enterozoa is had the effect of killing, above-mentioned all medicines share, and play spleen benefiting and stimulating the appetite altogether; Benefiting QI and nourishing blood helps digestion, the effect of anthelmintic, is used to treat the children's infantile malnutrition symptom definite effect.
The present invention adopts modern preparation technique, through extract, concentrate, processing technique such as drying, can be processed into acceptable clinically oral liquid, syrup, tablet, granule, the arbitrary dosage form of chewable tablet.
The present invention realizes through following method for preparing:
(1) get Periostracum Cicadae, Pericarpium Citri Reticulatae, be ground into coarse powder, extract volatile oil with steam distillation, collect volatile oil, sealing low temperature is placed, and is subsequent use; Medicinal residues filter, and other device of filtrating is placed subsequent use; Medicinal residues are subsequent use;
(2) get the Rhizoma Atractylodis Macrocephalae, the Radix Astragali, Rhizoma Dioscoreae, Endothelium Corneum Gigeriae Galli, Fructus Crataegi, Fructus Hordei Germinatus (parched), areca powder and be broken into coarse powder; Add step (1) gained medicinal residues, decoct 2～3 times each 1～2 hour with 8～12 times of water gagings; Decocting liquid filters; Merge with step (1) gained filtrating, be concentrated into relative density and be 1. 10～1. 30 clear paste, subsequent use;
(3) get above-mentioned clear paste and volatile oil, press the conventional formulation method, add proper auxiliary materials, molding, packing, check promptly gets.
The specific embodiment
EXAMPLE l
(1) get Periostracum Cicadae 60g, Pericarpium Citri Reticulatae 20g, be ground into coarse powder, extract volatile oil with steam distillation, collect volatile oil, sealing low temperature is placed, and is subsequent use; Medicinal residues filter, and other device of filtrating is placed subsequent use; Medicinal residues are subsequent use;
(2) get Rhizoma Atractylodis Macrocephalae 40g, Rhizoma Dioscoreae 40g, Endothelium Corneum Gigeriae Galli 16g, Fructus Crataegi 40g, Fructus Hordei Germinatus (parched) 16g, Radix Astragali 20g, Semen Arecae 16g; Be ground into coarse powder, add step (1) gained medicinal residues, decocted 2 hours with 12 times of water gagings; Decocting liquid filters: medicinal residues add 10 times of water gagings and decocted 1 hour, and decocting liquid filters; Medicinal residues add 8 times of water gagings again and decocted l hour, and decocting liquid filters; Filtrating merges with step (1) gained filtrating, under 60 ℃ of conditions, is evaporated to relative density and is 1. 15 clear paste, and is subsequent use;
(3) get above-mentioned clear paste, add sucrose 620g, sodium benzoate 2.6g, mix homogeneously adds water to 1000ml, embedding, and sterilization, packing, check promptly gets.
Embodiment 2
(1) get Periostracum Cicadae 120g, Pericarpium Citri Reticulatae 40g, be ground into coarse powder, extract volatile oil with steam distillation, collect volatile oil, sealing low temperature is placed, and is subsequent use; Medicinal residues filter, and other device of filtrating is placed subsequent use; Medicinal residues are subsequent use;
(2) get Rhizoma Atractylodis Macrocephalae 80g, Rhizoma Dioscoreae 80g, Endothelium Corneum Gigeriae Galli 32g, Fructus Crataegi 80g, Fructus Hordei Germinatus (parched) 32g, Radix Astragali 40g, Semen Arecae 32g, be ground into coarse powder, add step (1) gained medicinal residues, decocted 2 hours with 12 times of water gagings, decocting liquid filters; Medicinal residues add 10 times of water gagings and decocted 1.5 hours, and decocting liquid filters: medicinal residues add 10 times of water gagings again and decocted 1 hour, and decocting liquid filters; Filtrating merges with step (1) gained filtrating, is concentrated into relative density and is 1. 30 clear paste, and is subsequent use;
(3) get above-mentioned clear paste, add sucrose 925g, mix homogeneously is processed granule, drying, and granulate gets granule 1000g
(4) packing, packing, check promptly gets.
Embodiment 3
(1) get Periostracum Cicadae 120g, Pericarpium Citri Reticulatae 40g, be ground into coarse powder, extract volatile oil with steam distillation, collect volatile oil, sealing low temperature is placed, and is subsequent use; Medicinal residues filter, and other device of filtrating is placed subsequent use; Medicinal residues are subsequent use;
(2) get Rhizoma Atractylodis Macrocephalae 80g, Rhizoma Dioscoreae 80g, Endothelium Corneum Gigeriae Galli 32g, Fructus Crataegi 80g, Fructus Hordei Germinatus (parched) 32g, Radix Astragali 40g, Semen Arecae 32g, be ground into coarse powder, add step (1) gained medicinal residues, decocted 2 hours with 12 times of water gagings, decocting liquid filters; Medicinal residues add 10 times of water gagings and decocted 1.5 hours, and decocting liquid filters; Medicinal residues add 10 times of water gagings again and decocted l hour, and decocting liquid filters; Filtrating merges with step (1) gained filtrating, is concentrated into relative density and is 1. 30 clear paste, and is subsequent use;
(3) get above-mentioned clear paste, drying is ground into fine powder, crosses 100 mesh sieves, gets extract powder;
(4) get extract powder, process granule with 85% ethanol, drying, granulate gets granule;
(5) get granule, add 0.4% magnesium stearate, tabletting, packing, check promptly gets.
Claims (4)
1. treat the Chinese medicine of children's infantile malnutrition symptom, comprise following parts by weight of Chinese traditional medicine:
Periostracum Cicadae 10～40 weight portions
The Rhizoma Atractylodis Macrocephalae 10～30 weight portions
Rhizoma Dioscoreae 5～30 weight portions
Endothelium Corneum Gigeriae Galli 3～10 weight portions
Pericarpium Citri Reticulatae 5～30 weight portions
Fructus Crataegi 5～30 weight portions
Fructus Hordei Germinatus (parched) 5～10 weight portions
Semen Arecae 5～10 weight portions
The Radix Astragali 5 ~ 15 weight portions.
2. the Chinese medicine of treatment children's infantile malnutrition symptom as claimed in claim 1 is characterized in that, comprises following parts by weight of Chinese traditional medicine:
Periostracum Cicadae 30 weight portions
The Rhizoma Atractylodis Macrocephalae 20 weight portions
Rhizoma Dioscoreae 20 weight portions
Endothelium Corneum Gigeriae Galli 8 weight portions
Pericarpium Citri Reticulatae 10 weight portions
Fructus Crataegi 20 weight portions
Fructus Hordei Germinatus (parched) 8 weight portions
Semen Arecae 8 weight portions
The Radix Astragali 10 weight portions.
3. like the Chinese medicine of claim l or 2 described treatment children's infantile malnutrition symptoms, can be processed into oral liquid, syrup, tablet, granule, the arbitrary dosage form of chewable tablet.
4. like the preparation method of Chinese medicine of the arbitrary described treatment children's infantile malnutrition symptom of claim l to 3, comprise following preparation process:
(1) get Periostracum Cicadae, Pericarpium Citri Reticulatae, be ground into coarse powder, extract volatile oil with steam distillation, collect volatile oil, sealing low temperature is placed, and is subsequent use; Medicinal residues filter, and other device of filtrating is placed subsequent use; Medicinal residues are subsequent use;
(2) get the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Endothelium Corneum Gigeriae Galli, Fructus Crataegi, Fructus Hordei Germinatus (parched), the Radix Astragali, areca powder and be broken into coarse powder; Add step (1) gained medicinal residues, decoct 2～3 times each 1～2 hour with 8～12 times of water gagings; Decocting liquid filters; Merge with step (1) gained filtrating, be concentrated into relative density and be 1. 10～1. 30 clear paste, subsequent use;
(3) get above-mentioned clear paste and volatile oil, press the conventional formulation method, add proper auxiliary materials, molding, packing, check promptly gets.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2011104107818A CN102423435B (en) | 2011-12-12 | 2011-12-12 | Chinese medicine for treating infantile malnutrition and preparation method thereof |
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| CN2011104107818A CN102423435B (en) | 2011-12-12 | 2011-12-12 | Chinese medicine for treating infantile malnutrition and preparation method thereof |
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| CN102423435A true CN102423435A (en) | 2012-04-25 |
| CN102423435B CN102423435B (en) | 2013-05-01 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102657799A (en) * | 2012-05-23 | 2012-09-12 | 天津药业集团新郑股份有限公司 | External application for treatment of infantile anorexia and preparation method thereof |
| CN107551207A (en) * | 2017-10-30 | 2018-01-09 | 刘萍 | A kind of medicine for treating infantile malnutrition and preparation method thereof |
| CN108066667A (en) * | 2017-12-22 | 2018-05-25 | 苏州科技城医院 | Infant's antidiarrheal oral stomachic tonic liquor |
| CN116549595A (en) * | 2023-07-12 | 2023-08-08 | 云南琼月企业管理有限公司 | Pharmaceutical composition for treating functional dyspepsia of children, preparation and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101274077A (en) * | 2008-05-04 | 2008-10-01 | 北京中科仁和科技有限公司 | Medicament composition for curing children's anorexia and preparation thereof |
| CN101766765A (en) * | 2008-12-30 | 2010-07-07 | 北京中科仁和科技有限公司 | Granule for treating children indigestion |
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2011
- 2011-12-12 CN CN2011104107818A patent/CN102423435B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101274077A (en) * | 2008-05-04 | 2008-10-01 | 北京中科仁和科技有限公司 | Medicament composition for curing children's anorexia and preparation thereof |
| CN101766765A (en) * | 2008-12-30 | 2010-07-07 | 北京中科仁和科技有限公司 | Granule for treating children indigestion |
Non-Patent Citations (2)
| Title |
|---|
| 万力生等,1: "中医药治疗小儿厌食症的现状与展望", 《南京中医药大学学报(自然科学版)》 * |
| 金仁淑等,1: "中医药治疗小儿厌食症研究集粹", 《中医药学刊》 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102657799A (en) * | 2012-05-23 | 2012-09-12 | 天津药业集团新郑股份有限公司 | External application for treatment of infantile anorexia and preparation method thereof |
| CN102657799B (en) * | 2012-05-23 | 2014-02-12 | 天津药业集团新郑股份有限公司 | External application for treatment of infantile anorexia and preparation method thereof |
| CN107551207A (en) * | 2017-10-30 | 2018-01-09 | 刘萍 | A kind of medicine for treating infantile malnutrition and preparation method thereof |
| CN108066667A (en) * | 2017-12-22 | 2018-05-25 | 苏州科技城医院 | Infant's antidiarrheal oral stomachic tonic liquor |
| CN116549595A (en) * | 2023-07-12 | 2023-08-08 | 云南琼月企业管理有限公司 | Pharmaceutical composition for treating functional dyspepsia of children, preparation and application thereof |
| CN116549595B (en) * | 2023-07-12 | 2023-09-01 | 云南琼月企业管理有限公司 | Pharmaceutical composition for treating functional dyspepsia of children, preparation and application thereof |
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| CN102423435B (en) | 2013-05-01 |
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Granted publication date: 20130501 Termination date: 20131212 |