CN103415293B - 利用多硫酸化多糖的骨髓水肿的治疗 - Google Patents

利用多硫酸化多糖的骨髓水肿的治疗 Download PDF

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Publication number
CN103415293B
CN103415293B CN201280007433.9A CN201280007433A CN103415293B CN 103415293 B CN103415293 B CN 103415293B CN 201280007433 A CN201280007433 A CN 201280007433A CN 103415293 B CN103415293 B CN 103415293B
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China
Prior art keywords
polysulfate
treatment
bone marrow
pentosan
application
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Active
Application number
CN201280007433.9A
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English (en)
Chinese (zh)
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CN103415293A (zh
Inventor
彼得·戈什
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Paradigm Health Sciences Pty Ltd
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Paradigm Health Sciences Pty Ltd
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Priority claimed from AU2011900325A external-priority patent/AU2011900325A0/en
Application filed by Paradigm Health Sciences Pty Ltd filed Critical Paradigm Health Sciences Pty Ltd
Publication of CN103415293A publication Critical patent/CN103415293A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201280007433.9A 2011-02-02 2012-02-02 利用多硫酸化多糖的骨髓水肿的治疗 Active CN103415293B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2011900325A AU2011900325A0 (en) 2011-02-02 Treatment of bone marrow edema (oedema) with polysulfated polysaccharides
AU2011900325 2011-02-02
PCT/AU2012/000091 WO2012103588A1 (en) 2011-02-02 2012-02-02 Treatment of bone marrow edema (oedema) with polysulfated polysaccharides

Publications (2)

Publication Number Publication Date
CN103415293A CN103415293A (zh) 2013-11-27
CN103415293B true CN103415293B (zh) 2016-08-10

Family

ID=46602012

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280007433.9A Active CN103415293B (zh) 2011-02-02 2012-02-02 利用多硫酸化多糖的骨髓水肿的治疗

Country Status (15)

Country Link
US (6) US9101650B2 (cg-RX-API-DMAC7.html)
EP (1) EP2670412B1 (cg-RX-API-DMAC7.html)
JP (1) JP5883458B2 (cg-RX-API-DMAC7.html)
KR (1) KR101840079B1 (cg-RX-API-DMAC7.html)
CN (1) CN103415293B (cg-RX-API-DMAC7.html)
AU (1) AU2012212398B2 (cg-RX-API-DMAC7.html)
CA (1) CA2826166C (cg-RX-API-DMAC7.html)
DK (1) DK2670412T3 (cg-RX-API-DMAC7.html)
ES (1) ES2664611T3 (cg-RX-API-DMAC7.html)
MY (1) MY164728A (cg-RX-API-DMAC7.html)
NO (1) NO2670412T3 (cg-RX-API-DMAC7.html)
PT (1) PT2670412T (cg-RX-API-DMAC7.html)
SG (1) SG192238A1 (cg-RX-API-DMAC7.html)
TW (1) TWI520740B (cg-RX-API-DMAC7.html)
WO (1) WO2012103588A1 (cg-RX-API-DMAC7.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015059177A1 (en) * 2013-10-22 2015-04-30 Cell Receptor Ug Sulfated polysaccharides for use in the treatment of cancer
CA3071585A1 (en) * 2017-08-04 2019-02-07 Paradigm Biopharmaceuticals Ltd Treatment of bone marrow pathologies with polysulfated polysaccharides
US11911413B2 (en) 2018-02-16 2024-02-27 Proteobioactives Pty Limited Methods and compositions for the treatment of pain and/or inflammation
KR102796937B1 (ko) * 2018-02-28 2025-04-15 패러다임 바이오파마슈티컬스 리미티드 다황화된 다당류를 이용한 수술 후 관절통의 치료
JP2022512662A (ja) 2018-10-10 2022-02-07 パラダイム バイオファーマシューティカルズ リミテッド ポリ硫酸化多糖を用いた疼痛の治療

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1476328A (zh) * 2000-11-21 2004-02-18 ��������ķ������ 骨质疏松症的治疗

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5668116A (en) 1987-03-19 1997-09-16 Anthropharm Pty. Limited Anti-inflammatory compounds and compositions
US6564083B2 (en) * 2000-12-18 2003-05-13 Hoffmann-La Roche Inc. Bone marrow edema as predictive of susceptibility to developing progressive osteoarthritis
DE10225551A1 (de) * 2002-06-06 2003-12-24 Schering Ag Verwendung von oral verfügbaren Prostacyclinderivaten für die Herstellung eines Arzneimittels zur Behandlung von Krankheiten, die mit Knochenmarködemen assoziiert sind
CN101939417B (zh) 2007-12-04 2014-02-05 蛋白生物动力私人有限公司 祖细胞的保护和它们的分化的调节

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1476328A (zh) * 2000-11-21 2004-02-18 ��������ķ������ 骨质疏松症的治疗

Also Published As

Publication number Publication date
NO2670412T3 (cg-RX-API-DMAC7.html) 2018-06-02
US11406660B2 (en) 2022-08-09
US10610542B2 (en) 2020-04-07
EP2670412A4 (en) 2015-07-08
US20140024614A1 (en) 2014-01-23
US20150297633A1 (en) 2015-10-22
KR20140012655A (ko) 2014-02-03
KR101840079B1 (ko) 2018-03-19
SG192238A1 (en) 2013-09-30
CA2826166A1 (en) 2012-08-09
EP2670412B1 (en) 2018-01-03
US20240156858A1 (en) 2024-05-16
MY164728A (en) 2018-01-30
AU2012212398B2 (en) 2014-06-05
US20210015849A1 (en) 2021-01-21
PT2670412T (pt) 2018-03-20
JP2014504613A (ja) 2014-02-24
US9861657B2 (en) 2018-01-09
WO2012103588A1 (en) 2012-08-09
US20180021369A1 (en) 2018-01-25
TW201309307A (zh) 2013-03-01
CN103415293A (zh) 2013-11-27
DK2670412T3 (en) 2018-03-12
EP2670412A1 (en) 2013-12-11
ES2664611T3 (es) 2018-04-20
TWI520740B (zh) 2016-02-11
US20220362284A1 (en) 2022-11-17
AU2012212398A1 (en) 2013-09-19
US9101650B2 (en) 2015-08-11
JP5883458B2 (ja) 2016-03-15
CA2826166C (en) 2017-05-09

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