TWI520740B - 利用多硫酸化多醣之骨髓水腫(水腫)的治療 - Google Patents

利用多硫酸化多醣之骨髓水腫(水腫)的治療 Download PDF

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Publication number
TWI520740B
TWI520740B TW101103252A TW101103252A TWI520740B TW I520740 B TWI520740 B TW I520740B TW 101103252 A TW101103252 A TW 101103252A TW 101103252 A TW101103252 A TW 101103252A TW I520740 B TWI520740 B TW I520740B
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TW
Taiwan
Prior art keywords
polysulfate
bone marrow
treatment
intra
sulfate
Prior art date
Application number
TW101103252A
Other languages
English (en)
Chinese (zh)
Other versions
TW201309307A (zh
Inventor
彼得 果斯
Original Assignee
模範健康科技私人企業有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2011900325A external-priority patent/AU2011900325A0/en
Application filed by 模範健康科技私人企業有限公司 filed Critical 模範健康科技私人企業有限公司
Publication of TW201309307A publication Critical patent/TW201309307A/zh
Application granted granted Critical
Publication of TWI520740B publication Critical patent/TWI520740B/zh

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
TW101103252A 2011-02-02 2012-02-01 利用多硫酸化多醣之骨髓水腫(水腫)的治療 TWI520740B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AU2011900325A AU2011900325A0 (en) 2011-02-02 Treatment of bone marrow edema (oedema) with polysulfated polysaccharides

Publications (2)

Publication Number Publication Date
TW201309307A TW201309307A (zh) 2013-03-01
TWI520740B true TWI520740B (zh) 2016-02-11

Family

ID=46602012

Family Applications (1)

Application Number Title Priority Date Filing Date
TW101103252A TWI520740B (zh) 2011-02-02 2012-02-01 利用多硫酸化多醣之骨髓水腫(水腫)的治療

Country Status (15)

Country Link
US (6) US9101650B2 (cg-RX-API-DMAC7.html)
EP (1) EP2670412B1 (cg-RX-API-DMAC7.html)
JP (1) JP5883458B2 (cg-RX-API-DMAC7.html)
KR (1) KR101840079B1 (cg-RX-API-DMAC7.html)
CN (1) CN103415293B (cg-RX-API-DMAC7.html)
AU (1) AU2012212398B2 (cg-RX-API-DMAC7.html)
CA (1) CA2826166C (cg-RX-API-DMAC7.html)
DK (1) DK2670412T3 (cg-RX-API-DMAC7.html)
ES (1) ES2664611T3 (cg-RX-API-DMAC7.html)
MY (1) MY164728A (cg-RX-API-DMAC7.html)
NO (1) NO2670412T3 (cg-RX-API-DMAC7.html)
PT (1) PT2670412T (cg-RX-API-DMAC7.html)
SG (1) SG192238A1 (cg-RX-API-DMAC7.html)
TW (1) TWI520740B (cg-RX-API-DMAC7.html)
WO (1) WO2012103588A1 (cg-RX-API-DMAC7.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015059177A1 (en) * 2013-10-22 2015-04-30 Cell Receptor Ug Sulfated polysaccharides for use in the treatment of cancer
CA3071585A1 (en) * 2017-08-04 2019-02-07 Paradigm Biopharmaceuticals Ltd Treatment of bone marrow pathologies with polysulfated polysaccharides
US11911413B2 (en) 2018-02-16 2024-02-27 Proteobioactives Pty Limited Methods and compositions for the treatment of pain and/or inflammation
KR102796937B1 (ko) * 2018-02-28 2025-04-15 패러다임 바이오파마슈티컬스 리미티드 다황화된 다당류를 이용한 수술 후 관절통의 치료
JP2022512662A (ja) 2018-10-10 2022-02-07 パラダイム バイオファーマシューティカルズ リミテッド ポリ硫酸化多糖を用いた疼痛の治療

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5668116A (en) 1987-03-19 1997-09-16 Anthropharm Pty. Limited Anti-inflammatory compounds and compositions
US6593310B1 (en) * 2000-11-21 2003-07-15 Arthropharm Pty. Ltd. Treatment of osteoporosis
US6564083B2 (en) * 2000-12-18 2003-05-13 Hoffmann-La Roche Inc. Bone marrow edema as predictive of susceptibility to developing progressive osteoarthritis
DE10225551A1 (de) * 2002-06-06 2003-12-24 Schering Ag Verwendung von oral verfügbaren Prostacyclinderivaten für die Herstellung eines Arzneimittels zur Behandlung von Krankheiten, die mit Knochenmarködemen assoziiert sind
CN101939417B (zh) 2007-12-04 2014-02-05 蛋白生物动力私人有限公司 祖细胞的保护和它们的分化的调节

Also Published As

Publication number Publication date
NO2670412T3 (cg-RX-API-DMAC7.html) 2018-06-02
US11406660B2 (en) 2022-08-09
US10610542B2 (en) 2020-04-07
EP2670412A4 (en) 2015-07-08
CN103415293B (zh) 2016-08-10
US20140024614A1 (en) 2014-01-23
US20150297633A1 (en) 2015-10-22
KR20140012655A (ko) 2014-02-03
KR101840079B1 (ko) 2018-03-19
SG192238A1 (en) 2013-09-30
CA2826166A1 (en) 2012-08-09
EP2670412B1 (en) 2018-01-03
US20240156858A1 (en) 2024-05-16
MY164728A (en) 2018-01-30
AU2012212398B2 (en) 2014-06-05
US20210015849A1 (en) 2021-01-21
PT2670412T (pt) 2018-03-20
JP2014504613A (ja) 2014-02-24
US9861657B2 (en) 2018-01-09
WO2012103588A1 (en) 2012-08-09
US20180021369A1 (en) 2018-01-25
TW201309307A (zh) 2013-03-01
CN103415293A (zh) 2013-11-27
DK2670412T3 (en) 2018-03-12
EP2670412A1 (en) 2013-12-11
ES2664611T3 (es) 2018-04-20
US20220362284A1 (en) 2022-11-17
AU2012212398A1 (en) 2013-09-19
US9101650B2 (en) 2015-08-11
JP5883458B2 (ja) 2016-03-15
CA2826166C (en) 2017-05-09

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