CN103393941B - Drug for treating cerebral infarction - Google Patents
Drug for treating cerebral infarction Download PDFInfo
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- CN103393941B CN103393941B CN201310323620.4A CN201310323620A CN103393941B CN 103393941 B CN103393941 B CN 103393941B CN 201310323620 A CN201310323620 A CN 201310323620A CN 103393941 B CN103393941 B CN 103393941B
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Abstract
The invention discloses a drug for treating cerebral infarction. The raw materials used for preparing the effective components of the drug are composed of sophora fruit, lethariella cladonioides, medicated leaven, shellac, renanthera coccinea, sweet wormwood, scallion root, blumea balsamifera, Chinese honey locust, serissa serissoide, aconitum kusnezoffii, peucedanum terebinthaceum, herba Inulae, cacumen biotae, magnetite and bile arisaema. The drug disclosed by the invention is prepared by the modern advanced pharmaceutical technology and has the functions of invigorating the circulation of blood, inducing resuscitation, improving blood and oxygen supply of brain tissues, recovering the functions of the cerebral nervous system, and the drug has excellent curative effect on such diseases as cerebral hemorrhage and cerebral infarction and such symptoms caused by cerebral hemorrhage and cerebral infarction sequelae as stroke, partial paralysis, slurred speech, memory deterioration, facial paralysis, and limb stiffness; the drug disclosed by the invention is a pure traditional Chinese medicine preparation, the selected herbs are properly combined, the drug has the functions of replenishing blood for nourishing heart, promoting blood circulation to remove blood stasis, and ensuring resuscitation with aromatics, and is free of toxic side effect, quick in treatment effect on cerebral infarction, high in cure rate and free of sequelae.
Description
Technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of medicine for the treatment of cerebral infarction.
Background technology
Cerebral infarction is commonly called as " apoplexy " or " apoplexy ", due to cerebral atherosclerosis, tunica intima damage makes cerebral arteries chamber narrow, and then many factors forms local thrombus, stricture of artery is increased the weight of or entirely shut, cause cerebral tissue ischemia, anoxia, necrosis, cause a kind of cerebrovascular of delayed ischemic neurological deficits.Main manifestations is office's source property neurologic impairment symptom of the bursts such as hemiplegia, hemianesthesia, speech be unclear clinically, is more common in 45～70 years old middle-aged and elderly people.
But, along with living standard is more and more higher, people's pressure is also increasing, the incidence rate of cerebrovascular disease increases thereupon, the age of onset of cerebral infarction is also tending towards rejuvenation, the pathogenic factor of cerebral infarction is mainly relevant with the vessel size of blocking, and the common disease such as hypertension, hyperlipidemia is also the risk factor that causes cerebral infarction; In addition, bad living habit, also easily causes cerebral infarction.
Should accomplish timely discovery for cerebral infarction disease, treatment in time, and in existing technology, western medicine cerebral infarction is mainly to adopt medicine to carry out thrombolytic, anticoagulant, fall fine etc. or implement operative treatment, medical expense is very expensive, not only bring heavy financial burden to patient, and therapeutic effect is not obvious, very easily recurrence.And most Cerebral Infarction Patients are old people, there is very big risk in operative treatment concerning old people.
For this reason, we should be theoretical in conjunction with traditional Chinese medical science medicine, develops new medicine and come safely and effectively cerebral infarction disease to be treated.
Summary of the invention
The object of this invention is to provide a kind of medicine for the treatment of cerebral infarction, treat the disease such as cerebral hemorrhage, cerebral infarction; Medicine of the present invention is adopted modern advanced pharmaceutical technology and is made, and opening the orifice and activating blood circulation, can improve cerebral tissue blood supply oxygen-supplying amount, recovers cerebral nervous system function.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a medicine for cerebral infarction, raw material composition and the parts by weight of making described effective ingredient are:
Fructus Sophorae 60-90 part spun gold brush 45-75 part Massa Medicata Fermentata 40-70 part Lacca 45-75 part
Herba Renantherae coccineae 42-76 part Herba Artemisiae Annuae 40-70 part Radix Allii Fistulosi 25-60 part Herba Blumeae Balsamiferae 60-80 part
Fructus Gleditsia 28-48 part Serissa foetida 28-56 part Radix Aconiti Kusnezoffii 20-50 part Radix Peucedani Terebinthacei 20-50 part
Herba Inulae 25-45 part Cacumen Platycladi 32-56 part Magnetitum 20-45 part Arisaema Cum Bile 15-45 part.
Raw material composition and the parts by weight of making described effective ingredient are:
Fructus Sophorae 65-85 part spun gold brush 50-70 part Massa Medicata Fermentata 45-65 part Lacca 50-70 part
Herba Renantherae coccineae 48-68 part Herba Artemisiae Annuae 45-65 part Radix Allii Fistulosi 30-55 part Herba Blumeae Balsamiferae 65-75 part
Fructus Gleditsia 32-44 part Serissa foetida 34-50 part Radix Aconiti Kusnezoffii 25-45 part Radix Peucedani Terebinthacei 25-45 part
Herba Inulae 28-43 part Cacumen Platycladi 36-52 part Magnetitum 24-41 part Arisaema Cum Bile 20-40 part.
Raw material composition and the parts by weight of making described effective ingredient are:
Fructus Sophorae 70-80 part spun gold brush 55-65 part Massa Medicata Fermentata 50-60 part Lacca 55-65 part
Herba Renantherae coccineae 54-62 part Herba Artemisiae Annuae 50-60 part Radix Allii Fistulosi 35-50 part Herba Blumeae Balsamiferae 67-72 part
Fructus Gleditsia 36-40 part Serissa foetida 38-46 part Radix Aconiti Kusnezoffii 30-40 part Radix Peucedani Terebinthacei 30-40 part
Herba Inulae 31-38 part Cacumen Platycladi 40-48 part Magnetitum 28-37 part Arisaema Cum Bile 25-35 part.
Raw material composition and the parts by weight of making described effective ingredient are:
60 parts of 55 parts of Laccas of 75 parts of spun gold 60 parts of Massa Medicata Fermentata of brush of the Fructus Sophorae
70 parts of 42 parts of Herba Blumeae Balsamiferaes of 55 parts of Radix Allii Fistulosi of 58 portions of Herba Artemisiae Annuaes of Herba Renantherae coccineae
35 parts of 35 parts of Radix Peucedani Terebinthacei of 42 parts of Radix Aconiti Kusnezoffiis of 38 parts of Serissa foetida of Fructus Gleditsia
30 parts of 33 parts of Arisaema Cum Bile of 45 parts of Magnetitums of 35 portions of Cacumen Platycladis of Herba Inulae.
Treat a preparation method for the medicine of cerebral infarction, comprise following processing step:
(1) get the Fructus Sophorae and Herba Artemisiae Annuae and clean, mash, add the distilled water of 2 times of amounts, after mixing completely, filter, taking juice is for subsequent use;
(2) get Herba Renantherae coccineae, Radix Allii Fistulosi, Fructus Gleditsia, Radix Aconiti Kusnezoffii, Radix Peucedani Terebinthacei, Cacumen Platycladi and Arisaema Cum Bile and clean, the distilled water immersion 4-5 hour that adds 8-10 doubly to measure, heated and boiled 3-4 hour, extracts; Again add 6-8 doubly to measure distilled water, heated and boiled 2-3 hour, extracts; Finally add 4-6 doubly to measure distilled water heated and boiled 1-2 hour, extract; Merge three times extracting solution, filter, obtain filtrate, be condensed into dry extract for subsequent use;
(3) gained dry extract in step (2) being added to volumetric concentration is 90% alcoholic solution, and hold over night extracts supernatant, and the extractum precipitating is for subsequent use;
(4) spun gold is brushed to cleaning, drying, put into mortar and grind into powder, cross 200 order fine powders, gained fine powder is added to the distilled water of 4 times of amounts, stir, until completely dissolved, filter, get filtrate for subsequent use;
(5) by Lacca dedust bits, clean, add 85% alcoholic solution of 3 times of amounts, soak 2-3 hour, take out, dry, put into mortar, grind into powder, cross 200 order fine powders, for subsequent use;
(6) get Massa Medicata Fermentata, Herba Blumeae Balsamiferae, Serissa foetida, Herba Inulae and Magnetitum and clean, microwave drying, pulverizing is 200 orders, and adding volumetric concentration is that 75% alcoholic solution extracts 1.5-2 hour in 70-90 DEG C of hot reflux, and elimination medicinal residues are got filtrate for subsequent use;
(7) juice making in step (1)-(6), extractum, filtrate and fine powder are mixed, add assistant medicament, make tablet, the medicine of described treatment cerebral infarction.
The property of medicine of the present invention's Chinese medicine used is as follows:
The Fructus Sophorae: bitter in the mouth, cold in nature.Return liver, large intestine channel.Clearing away heat-fire, cooling blood for hemostasis.Have blood in stool for intestinal heat, hemorrhoid are swollen hemorrhage, liver-heat headache, dizzy conjunctival congestion.Supplement to the Herbal carries: " parasite killing removes wind, and improving eyesight removes hot tears, hot blast unhappiness between brains ambition, and dizziness due to wind pathogen wish is fallen, and salivation, as liquor-saturated, ripples as person on ship car in mind.”
Spun gold brush: bitter in the mouth, property is flat.GUIXIN, Liver Channel.Calm the nerves, suppressing the hyperactive liver, invigorates blood circulation, sore.Cure mainly insomnia, epilepsy, dizzy, traumatic injury, burn due to hot liquid or fire.
Massa Medicata Fermentata: sweet in the mouth, pungent, warm in nature, nontoxic.Return spleen, stomach warp.Invigorating the spleen and regulating the stomach, promoting digestion and removing stagnation.Cure mainly retention of food and drink, dyspepsia, distension and fullness in the abdomen, inappetence, vomiting dysentery." book on Chinese herbal medicine is stated " carries: " summer-heat that cures the wound, being affected by fluid-retention food, hinders overstrain, malaria flatulence due to stagnation of QI card, edema distension gathers, cough due to fluid-retention, vomiting regurgitation, cholera, blood-retention, pained, gastric abscess, hypochondriac pain, numbness flaccidity is dizzy, and heavy sensation of the body can not be eaten jaundice.”
Lacca: sweet in the mouth, salty, property is flat.Sterilization, hemostasis, blood circulation promoting and blood stasis dispelling.For blood consumptive disease heat, toxic swelling malignant boil, blood stasis is not changed.Tang Materia Medica carries: " main the five internal organs pathogen, leukorrhagia, pained, removing mass blood, incised wound raw meat.”
Herba Renantherae coccineae: bitter in the mouth, pungent, property is flat.Return liver, kidney channel.Expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling.Cure mainly rheumatic arthralgia, fracture." Xinhua's book on Chinese herbal medicine outline " carries: " blood circulation promoting and blood stasis dispelling cures mainly fracture.”
Herba Artemisiae Annuae: bitter in the mouth, micro-pungent; Cold in nature.Return liver, gallbladder meridian.Heat clearing away, expelling summer-heat, except steaming, preventing the attack (or recurrence) of malaria.Cure mainly summer-heat, heat-damp in summer, hygropyrexia, fever due to yin deficiency, malaria, jaundice." Treatise on Dietetic Therapy " carries: " QI invigorating, long hair, invigorating middle warmer, improving eyesight, very pathogenic wind toxic.Control hectic fever due to YIN-deficiency.Ashing drenches juice, and Calx decocts, and controls malignant boil scar dimple.”
Radix Allii Fistulosi: acrid in the mouth, property is flat, returns lung meridian.Expelling wind and cold, removing toxic substances, dissipating blood stasis.Cure mainly headche due to wind-cold, abscess of the throat, hemorrhoid, cold injury." not Lu " carries: " main cold headache.”
Herba Blumeae Balsamiferae: acrid in the mouth, micro-hardship; Warm in nature.Expelling wind and removing dampness, warming middle-JIAO to stop diarrhea, promoting blood circulation and detoxication.Cure mainly anemofrigid cold, wind syndrome of head headache, rheumatic arthralgia, cold-damp dysentery, taeniasis, venom, traumatic pain, tinea skin ulcer." the SHENGCAO property of medicine standby will " carries: " detumescence of dispeling the wind, the dehumidifying of invigorating blood circulation.Control traumatic injury, apply wind syndrome due to invasion of wind when drinking foot.”
Fructus Gleditsia: acrid in the mouth, salty is warm in nature, poisonous.Return lung, large intestine channel.Expelling phlegm for arresting cough, logical the closing of having one's ideas straightened out, parasite killing eliminating stagnation.Cure mainly productive cough dyspnea with fullness of the chest, apoplexy locked mouth, accumulation and obstruction of sputum; Coma in silence, epilepsy, sore throat, constipation and anuresis, carbuncle scabies." Bencao Tujing " carries: " dispelling wind gas.”
Serissa foetida: lightly seasoned, micro-pungent, cool in nature.Invigorating spleen to remove dampness, soothing liver-QI is invigorated blood circulation.For infantile malnutrition, acute, chronic hepatitis, amenorrhea, leucorrhea, lumbago due to pathogenic wind-dampness; " Chinese herbal medicine handbook is commonly used in Shanghai " carries: " invigorate blood circulation, detumescence, dispels the wind, and removing dampness, has again strong effect.Control woman's amenorrhea, leukorrhagia, dizzy unable.”
Radix Aconiti Kusnezoffii: acrid in the mouth, hardship, hot in nature; Large poison.GUIXIN, liver, spleen channel.Expelling wind and removing dampness; Dispelling cold by warming the meridian; Reducing swelling and alleviating pain.Main anemofrigid-damp arthralgia, arthralgia, wind syndrome of head headache, apoplectic dyscinesia, trusted subordinate's cold type of pain, colic of cold type is had a pain, traumatic injury, swelling and pain due to blood stasis, carbuncle of yin nature toxic swelling, narcotic analgesic." herbal classic " carries: " main apoplexy, aversion to wind, washes out antiperspirant, eliminating cold-damp numbness, cough with dyspnea, removing mass gathers cold and heat.”
Radix Peucedani Terebinthacei: bitter in the mouth, pungent, cool in nature, return lung, Liver Channel.Loose wind heat clearing away, lowering the adverse-rising QI and dispelling phlegm.Cure mainly flu, cough, phlegm dyspnea, the dizzy pain of wind syndrome of head." Bencao Tujing " carries: " treat the dizzy pain of wind syndrome of head.”
Herba Inulae: salty in the mouth, warm in nature.Return spleen, large intestine channel.Dispersing wind and cold, the drink that reduces phlegm, detumescence poison, wind-damp dispelling.Main cough due to wind and cold, latent fluid-retention phlegm dyspnea, distending pain in the hypochondrium, can pyogenic infections from tumour or sore, rheumatalgia." Traditional Chinese Medicine in Sichuan will " carries: " relieving cough and resolving phlegm, Dingchuan is except drink.Control heart spleen latent fluid-retention, distending pain in the hypochondrium, expectorant knot in lung, saliva is as shellac varnish, and pathogenic wind arthralgia chiefly caused by damp pathogen." modern medicine study confirmation, Herba Inulae has relaxing muscles and tendons to promote blood circulation effect.
Cacumen Platycladi: sweet in the mouth, pungent, micro-hardship, property is flat.Expelling wind and clearing away heat, calms the nerves, and hemostasia and promoting granulation is separated heating, dampness, analgesia.For fever and headache, leucorrhea; Traumatic hemorrhage is controlled in external.
Magnetitum: salty in the mouth, cold in nature, return liver, the heart, kidney channel.Suppressing the hyperactive liver and subsiding YANG, hearing-improing and eyesight improving, tranquillizing the mind by relieving convulsion, helping inspiration to relieve asthma.Be used for having a dizzy spell, blurring of vision, Hiccough and deaf, palpitation with fear insomnia, the asthma of suffering from a deficiency of the kidney." Japan hanako materia medica " carries: " control eye dusk, muscles and bones is thin and weak, mends five kinds of strain and seven kinds of impairment, except irritated, and detumescence poison.”
Arisaema Cum Bile: bitter in the mouth, micro-pungent, cool in nature.Return liver, gallbladder, lung meridian.Clearing away fire and eliminating phlegm, arresting convulsion relieves dizziness, high fever, infantile convulsions, epilepsy, etc.Cure mainly apoplexy, infantile convulsion, epilepsy, headache, dizzy, breathe heavily and cough." medicine justice " carries: " cure mainly all apoplexy, Feng Epilepsy, infantile convulsion, wind syndrome of head, dizzy, old god is slow-witted, and children's sends out and jerks, puerperal severe palpitation.”
The present invention compared with prior art, has following beneficial effect:
1, medicine of the present invention is adopted modern advanced pharmaceutical technology and is made, opening the orifice and activating blood circulation, can improve cerebral tissue blood supply oxygen-supplying amount, recover cerebral nervous system function, for the disease such as cerebral hemorrhage, cerebral infarction, and the apoplexy, hemiplegia, the slurred speech that cause because of cerebral hemorrhage, cerebral infarction sequela, hypomnesis, facial hemiparalysis, extremity are stiff etc., and symptom has significant curative effect.
2, medicine of the present invention is pure Chinese medicinal preparation, meets the traditional Chinese medical science and modern medicine theory for treatment cerebral infarction, and selected medical material compatibility is suitable, replenishing blood for nourishing heart, and blood circulation promoting and blood stasis dispelling, causing resuscitation with aromatic drugs, have no side effect, treatment cerebral infarction instant effect, cure rate is high, does not stay sequela.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is done further and supplemented, but do not limit the present invention in any way.
Embodiment 1
Raw material composition and the weight of effective ingredient of the present invention are:
Fructus Sophorae 85g spun gold brush 70g Massa Medicata Fermentata 65g Lacca 70g
Herba Renantherae coccineae 68g Herba Artemisiae Annuae 65g Radix Allii Fistulosi 55g Herba Blumeae Balsamiferae 75g
Fructus Gleditsia 44g Serissa foetida 50g Radix Aconiti Kusnezoffii 45g Radix Peucedani Terebinthacei 45g
Herba Inulae 43g Cacumen Platycladi 52g Magnetitum 41g Arisaema Cum Bile 40g.
The preparation method of medicine of the present invention, comprises following processing step:
(1) get the Fructus Sophorae and Herba Artemisiae Annuae and clean, mash, add the distilled water of 2 times of amounts, after mixing completely, filter, taking juice is for subsequent use;
(2) get Herba Renantherae coccineae, Radix Allii Fistulosi, Fructus Gleditsia, Radix Aconiti Kusnezoffii, Radix Peucedani Terebinthacei, Cacumen Platycladi and Arisaema Cum Bile and clean, the distilled water immersion 4-5 hour that adds 8-10 doubly to measure, heated and boiled 3-4 hour, extracts; Again add 6-8 doubly to measure distilled water, heated and boiled 2-3 hour, extracts; Finally add 4-6 doubly to measure distilled water heated and boiled 1-2 hour, extract; Merge three times extracting solution, filter, obtain filtrate, be condensed into dry extract for subsequent use;
(3) gained dry extract in step (2) being added to volumetric concentration is 90% alcoholic solution, and hold over night extracts supernatant, and the extractum precipitating is for subsequent use;
(4) spun gold is brushed to cleaning, drying, put into mortar and grind into powder, cross 200 order fine powders, gained fine powder is added to the distilled water of 4 times of amounts, stir, until completely dissolved, filter, get filtrate for subsequent use;
(5) by Lacca dedust bits, clean, add 85% alcoholic solution of 3 times of amounts, soak 2-3 hour, take out, dry, put into mortar, grind into powder, cross 200 order fine powders, for subsequent use;
(6) get Massa Medicata Fermentata, Herba Blumeae Balsamiferae, Serissa foetida, Herba Inulae and Magnetitum and clean, microwave drying, pulverizing is 200 orders, and adding volumetric concentration is that 75% alcoholic solution extracts 1.5-2 hour in 70-90 DEG C of hot reflux, and elimination medicinal residues are got filtrate for subsequent use;
(7) juice making in step (1)-(6), extractum, filtrate and fine powder are mixed, add assistant medicament, make tablet, the medicine of described treatment cerebral infarction.
Usage and dosage: oral, warm water delivery service after meal, each a slice, every day three times, 15 days is a course for the treatment of, and can cure four to six courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Embodiment 2
Raw material composition and the weight of effective ingredient of the present invention are:
Fructus Sophorae 80g spun gold brush 65g Massa Medicata Fermentata 60g Lacca 65g
Herba Renantherae coccineae 62g Herba Artemisiae Annuae 60g Radix Allii Fistulosi 50g Herba Blumeae Balsamiferae 72g
Fructus Gleditsia 40g Serissa foetida 46g Radix Aconiti Kusnezoffii 40g Radix Peucedani Terebinthacei 40g
Herba Inulae 38g Cacumen Platycladi 48g Magnetitum 37g Arisaema Cum Bile 35g.
The present embodiment process for preparing medicine, processing step and usage and dosage are identical with embodiment 1.
Embodiment 3
Raw material composition and the weight of effective ingredient of the present invention are:
Fructus Sophorae 75g spun gold brush 60g Massa Medicata Fermentata 55g Lacca 60g
Herba Renantherae coccineae 58g Herba Artemisiae Annuae 55g Radix Allii Fistulosi 42g Herba Blumeae Balsamiferae 70g
Fructus Gleditsia 38g Serissa foetida 42g Radix Aconiti Kusnezoffii 35g Radix Peucedani Terebinthacei 35g
Herba Inulae 35g Cacumen Platycladi 45g Magnetitum 33g Arisaema Cum Bile 30g.
The present embodiment process for preparing medicine, processing step and usage and dosage are identical with embodiment 1.
Embodiment 4
Raw material composition and the weight of effective ingredient of the present invention are:
Fructus Sophorae 65g spun gold brush 52g Massa Medicata Fermentata 48g Lacca 50g
Herba Renantherae coccineae 51g Herba Artemisiae Annuae 45g Radix Allii Fistulosi 34g Herba Blumeae Balsamiferae 62g
Fructus Gleditsia 33g Serissa foetida 32g Radix Aconiti Kusnezoffii 30g Radix Peucedani Terebinthacei 30g
Herba Inulae 30g Cacumen Platycladi 35g Magnetitum 25g Arisaema Cum Bile 20g.
The present embodiment process for preparing medicine, processing step and usage and dosage are identical with embodiment 1.
Clinical data:
1, case selection: choose Cerebral Infarction Patients 230 examples, be divided at random two groups, treatment group 120 examples, matched group 110 examples, treatment group is taken medicine of the present invention and is carried out clinical observation, and matched group is taken tolperisone hydrochloride sheet, and by specification uses.
2, Therapeutic Method:
Oral medicine of the present invention, warm water delivery service after meal, each a slice, every day three times, 15 days is a course for the treatment of, and can cure four to six courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
3, curative effect determinate standard:
(1) recovery from illness: cerebral infarction transference cure, it is normal that body function recovers;
(3) take a turn for the better: cerebral infarction symptom is alleviated to some extent;
(4) invalid: symptom and feature are all without improving.
4, result:
Treatment group: recovery from illness 62 examples, 46 examples that take a turn for the better, invalid 12 examples, cure rate 51.7%, total effective rate 90%;
Matched group: recovery from illness 21 examples, 52 examples that take a turn for the better, invalid 37 examples, cure rate 19.1%, total effective rate 66.4%;
Above-mentioned clinical data demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is given an example:
1, congratulate certain, female, 28 years old, the worker of foreign enterprise, Shanghai people, because operating pressure is large, often overtime work, sleep wretched insufficiency, spirit is poor, and work overtime and suddenly fall in a swoon one day, be acute cerebral infarction after diagnosing, take 5 courses for the treatment of of medicine of the present invention, the state of an illness is cured completely.
2, Pueraria lobota, man, 46 years old, peasant, Diseasein Chengde people.Suffer from hypertension 2 years, while being in nooning last month, occur the symptom such as headache, dizziness without inducement, aggravation after getting up morning two days later, and accompany right side limb activity unfavorable.Lai Wo institute checks, is the cerebral infarction that hypertension causes through clinical diagnosis, takes after two courses for the treatment of of medicine of the present invention, and symptom alleviates, and continues to take four courses for the treatment of, and patient returns to one's perfect health, and follow-up investigation has no recurrence.
3, high certain, female, 54 years old, workman, people from Baoding, Hebei province.Occur that without obvious inducement left lower extremity is unable, when motion walking, need people to help, CT examination shows the multiple lacunar infarction in bilateral basal joint district, and myelinopathy, is diagnosed as apoplexy cerebral infarction.Take two courses for the treatment of of medicine of the present invention, symptom alleviates, and continues to take two courses for the treatment of, state of an illness recovery from illness.
4, bent certain, man, 79 years old, retirement professor, people from Jinan City, Shandong Province.When walking, fall down because of carelessness, head lands, and occurs that left lower extremity is unable, cannot climb, and with inarticulateness, bradykinesia.Be acute cerebral infarction through clinical diagnosis.Due to older, doctor does not advise operative treatment, takes three courses for the treatment of of medicine of the present invention, and symptom alleviates, and continues to take three courses for the treatment of, and conditions of patients recovery from illness, follows up a case by regular visits to, without recurrence.
Claims (5)
1. a medicine for the treatment of cerebral infarction, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Fructus Sophorae 60-90 part spun gold brush 45-75 part Massa Medicata Fermentata 40-70 part Lacca 45-75 part
Herba Renantherae coccineae 42-76 part Herba Artemisiae Annuae 40-70 part Radix Allii Fistulosi 25-60 part Herba Blumeae Balsamiferae 60-80 part
Fructus Gleditsia 28-48 part Serissa foetida 28-56 part Radix Aconiti Kusnezoffii 20-50 part Radix Peucedani Terebinthacei 20-50 part
Herba Inulae 25-45 part Cacumen Platycladi 32-56 part Magnetitum 20-45 part Arisaema Cum Bile 15-45 part;
The preparation method of making described medicine comprises following processing step:
(1) get the Fructus Sophorae and Herba Artemisiae Annuae and clean, mash, add the distilled water of 2 times of amounts, after mixing completely, filter, taking juice is for subsequent use;
(2) get Herba Renantherae coccineae, Radix Allii Fistulosi, Fructus Gleditsia, Radix Peucedani Terebinthacei, Cacumen Platycladi and Arisaema Cum Bile and clean, the distilled water immersion 4-5 hour that adds 8-10 doubly to measure, heated and boiled 3-4 hour, extracts; Again add 6-8 doubly to measure distilled water, heated and boiled 2-3 hour, extracts; Finally add 4-6 doubly to measure distilled water heated and boiled 1-2 hour, extract; Merge three times extracting solution, filter, obtain filtrate, be condensed into dry extract for subsequent use;
(3) gained dry extract in step (2) being added to volumetric concentration is 90% alcoholic solution, and hold over night extracts supernatant, and the extractum precipitating is for subsequent use;
(4) by spun gold brush and Herba Blumeae Balsamiferae decontamination, dry, put into mortar and grind into powder, cross 200 order fine powders, gained fine powder is added to the distilled water of 4 times of amounts, stir, until completely dissolved, filtration, gets filtrate for subsequent use;
(5) by Lacca dedust bits, clean, add 85% alcoholic solution of 3 times of amounts, soak 2-3 hour, take out, dry, put into mortar, grind into powder, cross 200 order fine powders, for subsequent use;
(6) get Massa Medicata Fermentata, Serissa foetida, Radix Aconiti Kusnezoffii, Herba Inulae and Magnetitum and clean, microwave drying, pulverizing is 200 orders, and adding volumetric concentration is that 75% alcoholic solution extracts 1.5-2 hour in 70-90 DEG C of hot reflux, and elimination medicinal residues are got filtrate for subsequent use;
(7) juice making in step (1)-(6), extractum, filtrate and fine powder are mixed, add assistant medicament, make tablet, the medicine of described treatment cerebral infarction.
2. a kind of medicine for the treatment of cerebral infarction according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Fructus Sophorae 65-85 part spun gold brush 50-70 part Massa Medicata Fermentata 45-65 part Lacca 50-70 part
Herba Renantherae coccineae 48-68 part Herba Artemisiae Annuae 45-65 part Radix Allii Fistulosi 30-55 part Herba Blumeae Balsamiferae 65-75 part
Fructus Gleditsia 32-44 part Serissa foetida 34-50 part Radix Aconiti Kusnezoffii 25-45 part Radix Peucedani Terebinthacei 25-45 part
Herba Inulae 28-43 part Cacumen Platycladi 36-52 part Magnetitum 24-41 part Arisaema Cum Bile 20-40 part.
3. a kind of medicine for the treatment of cerebral infarction according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Fructus Sophorae 70-80 part spun gold brush 55-65 part Massa Medicata Fermentata 50-60 part Lacca 55-65 part
Herba Renantherae coccineae 54-62 part Herba Artemisiae Annuae 50-60 part Radix Allii Fistulosi 35-50 part Herba Blumeae Balsamiferae 67-72 part
Fructus Gleditsia 36-40 part Serissa foetida 38-46 part Radix Aconiti Kusnezoffii 30-40 part Radix Peucedani Terebinthacei 30-40 part
Herba Inulae 31-38 part Cacumen Platycladi 40-48 part Magnetitum 28-37 part Arisaema Cum Bile 25-35 part.
4. a kind of medicine for the treatment of cerebral infarction according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
60 parts of 55 parts of Laccas of 75 parts of spun gold 60 parts of Massa Medicata Fermentata of brush of the Fructus Sophorae
70 parts of 42 parts of Herba Blumeae Balsamiferaes of 55 parts of Radix Allii Fistulosi of 58 portions of Herba Artemisiae Annuaes of Herba Renantherae coccineae
35 parts of 35 parts of Radix Peucedani Terebinthacei of 42 parts of Radix Aconiti Kusnezoffiis of 38 parts of Serissa foetida of Fructus Gleditsia
30 parts of 33 parts of Arisaema Cum Bile of 45 parts of Magnetitums of 35 portions of Cacumen Platycladis of Herba Inulae.
5. a preparation method for the medicine of the treatment of the treatment as described in claim 1-4 cerebral infarction, is characterized in that: comprise following processing step:
(1) get the Fructus Sophorae and Herba Artemisiae Annuae and clean, mash, add the distilled water of 2 times of amounts, after mixing completely, filter, taking juice is for subsequent use;
(2) get Herba Renantherae coccineae, Radix Allii Fistulosi, Fructus Gleditsia, Radix Peucedani Terebinthacei, Cacumen Platycladi and Arisaema Cum Bile and clean, the distilled water immersion 4-5 hour that adds 8-10 doubly to measure, heated and boiled 3-4 hour, extracts; Again add 6-8 doubly to measure distilled water, heated and boiled 2-3 hour, extracts; Finally add 4-6 doubly to measure distilled water heated and boiled 1-2 hour, extract; Merge three times extracting solution, filter, obtain filtrate, be condensed into dry extract for subsequent use;
(3) gained dry extract in step (2) being added to volumetric concentration is 90% alcoholic solution, and hold over night extracts supernatant, and the extractum precipitating is for subsequent use;
(4) by spun gold brush and Herba Blumeae Balsamiferae decontamination, dry, put into mortar and grind into powder, cross 200 order fine powders, gained fine powder is added to the distilled water of 4 times of amounts, stir, until completely dissolved, filtration, gets filtrate for subsequent use;
(5) by Lacca dedust bits, clean, add 85% alcoholic solution of 3 times of amounts, soak 2-3 hour, take out, dry, put into mortar, grind into powder, cross 200 order fine powders, for subsequent use;
(6) get Massa Medicata Fermentata, Serissa foetida, Radix Aconiti Kusnezoffii, Herba Inulae and Magnetitum and clean, microwave drying, pulverizing is 200 orders, and adding volumetric concentration is that 75% alcoholic solution extracts 1.5-2 hour in 70-90 DEG C of hot reflux, and elimination medicinal residues are got filtrate for subsequent use;
(7) juice making in step (1)-(6), extractum, filtrate and fine powder are mixed, add assistant medicament, make tablet, the medicine of described treatment cerebral infarction.
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| CN102266493A (en) * | 2011-07-13 | 2011-12-07 | 陶冶 | Traditional Chinese medicine for restoring consciousness and promoting mentality and production process thereof |
| CN102973678A (en) * | 2012-12-26 | 2013-03-20 | 房守和 | Chinese medicinal formulae for treating cerebral apoplexy and method of application thereof |
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| CN102973678A (en) * | 2012-12-26 | 2013-03-20 | 房守和 | Chinese medicinal formulae for treating cerebral apoplexy and method of application thereof |
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| 中风后遗症的中药治疗近况;高分飞等;《现代诊断与治疗》;20020731;第13卷(第04期);193-198,215 * |
| 高分飞等.中风后遗症的中药治疗近况.《现代诊断与治疗》.2002,第13卷(第04期), |
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