CN104857313A - Traditional Chinese medicine composition preparation for treating migraine and preparation method thereof - Google Patents
Traditional Chinese medicine composition preparation for treating migraine and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition preparation for treating migraine and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The raw materials of the effective ingredients of the traditional Chinese medicine composition preparation are as follows: ginseng, fortune holly fern rhizome, Korean aconite roof, Chinese pholidota pseudobulb or herb, pokeberry root, black soybean skin, daghestan sweetclover herb, uncaria sessilifructus, lotus leaf, rust-coloured crotalaria herb with root, blumea balsamifera DC., common elsholtzia herb, siphocranion macranthum, hibiscus and diversifolious pimpinella herb. The traditional Chinese medicine composition preparation is reasonable in prescription, excellent in efficacy and absorption effect, convenient to use, free of bad, toxic or side effect, and suitable for clinic treatment, and nursing popularization and application of migraine, and has an excellent curative effect for migraine as proved by clinical treatment.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to one and treat migrainous Chinese medicine composition preparation and preparation method thereof.
Background technology
Migraine is the headache of a kind of common repeated relapsing with symptoms such as Nausea and vomiting, photophobia, phonophobias.Patient's main clinical manifestation is head side or bilateral distending pain, in beating or rest pain, periodical attack, unilateral headache during outbreak, and sharp ache sometimes, tool pulsation, sometimes with nausea and vomiting, or photophobia, phonophobia, this headache is usually from eye socket or frons, to half expansion, also can throughout whole head.
The migrainous medicament categories of current treatment is a lot, and great majority western medicine, though this kind of medicine can alleviate disease to a certain extent, but cure the symptoms, not the disease, usually need Long-term taking medicine, just get back to the original state of an illness again once drug withdrawal, if inappropriate medication, also may fail to respond to any medical treatment and even increase the weight of disease.Therefore the migrainous Chinese medicine preparation of a kind of safe and effective treatment is researched and developed very with practical value.
Summary of the invention
The invention provides one and treat migrainous Chinese medicine composition preparation and preparation method thereof; Chinese medicine preparation prescription of the present invention is reasonable, and effect is good, easy to use, preparation good absorbing effect, without bad and toxic and side effects, through clinical verification, has excellent therapy effect to migraine, is suitable for migraine clinical treatment and nursing is applied.
For achieving the above object, technical scheme of the present invention is implemented as follows.
One treats migrainous Chinese medicine composition preparation, and raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Ginseng 60 ~ 95 parts of Cyrtomium fortunei J. Sm.s 55 ~ 85 parts of Radix Aconiti Coreanis 55 ~ 85 parts of Pseudobulbus Pholidotae Chinensis 50 ~ 80 parts
Radix Phytolaccae 45 ~ 75 parts of Testa sojae atricolors 45 ~ 75 parts of Herba Meliloti Suaveolentiss 45 ~ 75 parts of Uncaria sessilifructus Roxb 40 ~ 70 parts
Folium Nelumbinis 40 ~ 70 parts of Herba Crotalariae Ferrugineaes 35 ~ 60 parts of Herba Blumeae Balsamiferaes 30 ~ 60 parts of Herba Elsholtziae Ciliataes 30 ~ 60 parts
Wild vetch crow 25 ~ 50 parts is towards emperor's 20 ~ 40 parts of Herba pimpinellae diversifoliaes 20 ~ 40 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Ginseng 60 parts of Cyrtomium fortunei J. Sm.s 55 parts of Radix Aconiti Coreanis 55 parts of Pseudobulbus Pholidotae Chinensis 50 parts
Radix Phytolaccae 45 parts of Testa sojae atricolors 45 parts of Herba Meliloti Suaveolentiss 45 parts of Uncaria sessilifructus Roxb 40 parts
Folium Nelumbinis 40 parts of Herba Crotalariae Ferrugineaes 35 parts of Herba Blumeae Balsamiferaes 30 parts of Herba Elsholtziae Ciliataes 30 parts
Wild vetch crow 25 parts is towards emperor's 20 parts of Herba pimpinellae diversifoliaes 20 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Ginseng 80 parts of Cyrtomium fortunei J. Sm.s 70 parts of Radix Aconiti Coreanis 70 parts of Pseudobulbus Pholidotae Chinensis 65 parts
Radix Phytolaccae 60 parts of Testa sojae atricolors 60 parts of Herba Meliloti Suaveolentiss 65 parts of Uncaria sessilifructus Roxb 55 parts
Folium Nelumbinis 55 parts of Herba Crotalariae Ferrugineaes 45 parts of Herba Blumeae Balsamiferaes 40 parts of Herba Elsholtziae Ciliataes 45 parts
Wild vetch crow 35 parts is towards emperor's 30 parts of Herba pimpinellae diversifoliaes 30 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Ginseng 95 parts of Cyrtomium fortunei J. Sm.s 85 parts of Radix Aconiti Coreanis 85 parts of Pseudobulbus Pholidotae Chinensis 80 parts
Radix Phytolaccae 75 parts of Testa sojae atricolors 75 parts of Herba Meliloti Suaveolentiss 75 parts of Uncaria sessilifructus Roxb 70 parts
Folium Nelumbinis 70 parts of Herba Crotalariae Ferrugineaes 60 parts of Herba Blumeae Balsamiferaes 60 parts of Herba Elsholtziae Ciliataes 60 parts
Wild vetch crow 50 parts is towards emperor's 40 parts of Herba pimpinellae diversifoliaes 40 parts.
Treat a preparation method for migrainous Chinese medicine composition preparation, comprise following processing step:
(1) by Radix Ginseng, Cyrtomium fortunei J. Sm., Radix Aconiti Coreani, Pseudobulbus Pholidotae Chinensis, Radix Phytolaccae, Testa sojae atricolor, Herba Meliloti Suaveolentis, Uncaria sessilifructus Roxb,
Folium Nelumbinis, Herba Crotalariae Ferrugineae decontamination, be placed in container, adds the distilled water of 5 ~ 10 times, and 60 DEG C of lixiviates are after 3 ~ 5 hours, boil 1 ~ 2 hour, obtain extracting solution, filter, obtain filtrate, filtrate is concentrated into the extractum that relative density is 1 ~ 1.3, is cooled to room temperature, ultraviolet radiation sterilizing, for subsequent use;
(2) by Herba Blumeae Balsamiferae, Herba Elsholtziae Ciliatae, wild vetch crow, clean towards emperor, Herba pimpinellae diversifoliae, immerse the alcohol solution dipping 1 ~ 2 hour of 70% of 2 ~ 4 times amount, heating extraction 3 ~ 5 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the extractum of 1 ~ 1.3, be cooled to room temperature, ultraviolet radiation sterilizing, for subsequent use;
(3) by the extractum of step (1) gained, after fully mixing with the extractum of step (2) gained, can add or not add pharmaceutically acceptable adjuvant (disintegrating agent, binding agent etc.) and make various dosage form, as powder, granule, mixture etc., be the migrainous Chinese medicine composition preparation for the treatment of of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows.
Radix Ginseng: sweet in the mouth, micro-hardship, property is put down.Return spleen, lung, heart channel.Strongly invigorating primordial QI, multiple arteries and veins takes off admittedly, and invigorating the spleen to benefit the lung, promotes the production of body fluid, and calms the nerves.For weak body and prostration, cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung is breathed with cough, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, prolonged illness weakness with emaciation, palpitation with fear insomnia, sexual impotence cold womb; Heart failure, cardiogenic shock.
Cyrtomium fortunei J. Sm.: bitter in the mouth, cold nature.Heat-clearing and toxic substances removing, cooling blood for calming endogenous wind, loose expectorant hemostasis.Control acute diseases such as cholera and sunstroke dirty poisoning, malaria, dysentery, hepatitis, dizziness due to hyperactivity of liver-YANG is had a headache, hematemesis hematochezia, traumatic injury.
Radix Aconiti Coreani: acrid-sweet flavor, hot in nature.Return the warp such as liver, stomach.Dispel the wind expectorant, by cold-damp, and arresting convulsion epilepsy.Control middle wind-phlegm to stop up, facial hemiparalysis, headache, epilepsy, rheumatic arthralgia, tetanus.
Pseudobulbus Pholidotae Chinensis: sweet in the mouth, cool in nature.Yin nourishing, lung heat clearing, dampness removing, repercussive.Control dizzy, headache, cough, spit blood, infantile malnutrition.
Radix Phytolaccae: bitter in the mouth, cold in nature.Return lung, spleen, kidney, large intestine channel.To relieve oedema or abdominal distension through diuresis or purgation detumescence, detoxicating and resolving stagnation of pathogens.
Testa sojae atricolor: taste is micro-sweet, cool in nature.Return spleen, lung, kidney channel.Nourish blood suppressing the hyperactive liver, removing toxic substances of dispeling the wind.Main headache, deficiency of YIN dysphoria with smothery sensation, night sweat, migratory arthralgia, noxious dampness, carbuncle skin ulcer, dizzy.
Herba Meliloti Suaveolentis: acrid in the mouth, sweet, micro-hardship, cool in nature.Return liver, spleen, stomach warp.Clearing away summer-heat and eliminating dampness; Stomach invigorating and in.Main heat-damp in summer is uncomfortable in chest, and feeling of fullness in the head is had a headache.
Uncaria sessilifructus Roxb: sweet in the mouth, cold nature.Heat clearing away suppressing the hyperactive liver, promoting blood circulation to restore menstrual flow.Dizzy for having a headache, hypertension.
Folium Nelumbinis: bitter in the mouth, property is put down.Return liver, spleen, stomach warp.Clearing away summer-heat, sending up the lucid YANG, cooling blood for hemostasis.For summer-heat excessive thirst, diarrhea due to summer heat and dampness, diarrhea due to hypofunction of the spleen.
Herba Crotalariae Ferrugineae: bitter in the mouth, micro-acid, property is flat cold.Return lung meridian.Nourishing the kidney and liver, relieving cough and asthma, eliminating damp, detoxifying.Main tinnitus, deaf, the vertigo, furuncle swelling toxin.
Herba Blumeae Balsamiferae: acrid in the mouth, micro-hardship, warm in nature.Expelling wind and removing dampness, warming middle-JIAO to stop diarrhea, promoting blood circulation and detoxication.Main anemofrigid cold, wind syndrome of head is had a headache, rheumatic arthralgia, cold-damp dysentery.
Herba Elsholtziae Ciliatae: acrid in the mouth, micro-hardship, warm in nature.Dispel the wind and deliver, subduing swelling and detoxicating.Main headache, sore and toxic.
Wild vetch crow: acrid in the mouth, cool in nature.Wind and heat dispersing; Removing toxic substances and promoting subsidence of swelling.Main headache conjunctival congestion, carbuncle pyogenic infections from tumour or sore.
Towards emperor: sweet in the mouth, property is put down.Removing heat from the lung and dissipating phlegm, removing toxic substances pain relieving.For phlegm dyspnea cough, nervous headache.
Herba pimpinellae diversifoliae: acrid in the mouth, micro-hardship, warm in nature.Cold expelling, eliminate indigestion, blood stasis dispelling, detumescence.Control wind and cold, dysentery, infantile malnutrition.The present invention compared with prior art, has following beneficial effect:
(1) selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, and meet Chinese medicine and pharmacy and modern medicine theory, ingredients complements each other, to migraine Be very effective, safe and reliable, treating both the principal and secondary aspects of a disease, wide popularization and application on clinic;
(2) with the preparation method ratio of prior art, preparation method of the present invention is simple, and be applicable to suitability for industrialized production, extraction efficiency is high.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1.
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and parts by weight are:
Radix Ginseng 60 parts of Cyrtomium fortunei J. Sm.s 55 parts of Radix Aconiti Coreanis 55 parts of Pseudobulbus Pholidotae Chinensis 50 parts
Radix Phytolaccae 45 parts of Testa sojae atricolors 45 parts of Herba Meliloti Suaveolentiss 45 parts of Uncaria sessilifructus Roxb 40 parts
Folium Nelumbinis 40 parts of Herba Crotalariae Ferrugineaes 35 parts of Herba Blumeae Balsamiferaes 30 parts of Herba Elsholtziae Ciliataes 30 parts
Wild vetch crow 25 parts is towards emperor's 20 parts of Herba pimpinellae diversifoliaes 20 parts.
The preparation method of Chinese medicine composition preparation of the present invention, comprises following processing step:
(1) by Radix Ginseng, Cyrtomium fortunei J. Sm., Radix Aconiti Coreani, Pseudobulbus Pholidotae Chinensis, Radix Phytolaccae, Testa sojae atricolor, Herba Meliloti Suaveolentis, Uncaria sessilifructus Roxb,
Folium Nelumbinis, Herba Crotalariae Ferrugineae decontamination, be placed in container, adds the distilled water of 5 ~ 10 times, and 60 DEG C of lixiviates are after 3 ~ 5 hours, boil 1 ~ 2 hour, obtain extracting solution, filter, obtain filtrate, filtrate is concentrated into the extractum that relative density is 1 ~ 1.3, is cooled to room temperature, ultraviolet radiation sterilizing, for subsequent use.
(2) by Herba Blumeae Balsamiferae, Herba Elsholtziae Ciliatae, wild vetch crow, clean towards emperor, Herba pimpinellae diversifoliae, immerse the alcohol solution dipping 1 ~ 2 hour of 70% of 2 ~ 4 times amount, heating extraction 3 ~ 5 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the extractum of 1 ~ 1.3, be cooled to room temperature, ultraviolet radiation sterilizing, for subsequent use.
(3) by the extractum of step (1) gained, after fully mixing with the extractum of step (2) gained, can add or not add pharmaceutically acceptable adjuvant (disintegrating agent, binding agent etc.) and make various dosage form, as powder, granule, mixture etc., be the migrainous Chinese medicine composition preparation for the treatment of of the present invention.
Usage and dosage: oral, every day 3 times, the morning, noon and afternoon, respectively once each 27 days was a course for the treatment of, and usual 2 ~ 3 courses for the treatment of are effective, and severe patient is followed the doctor's advice the meal with wine amount of adding.
Embodiment 2.
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and parts by weight are:
Radix Ginseng 80 parts of Cyrtomium fortunei J. Sm.s 70 parts of Radix Aconiti Coreanis 70 parts of Pseudobulbus Pholidotae Chinensis 65 parts
Radix Phytolaccae 60 parts of Testa sojae atricolors 60 parts of Herba Meliloti Suaveolentiss 65 parts of Uncaria sessilifructus Roxb 55 parts
Folium Nelumbinis 55 parts of Herba Crotalariae Ferrugineaes 45 parts of Herba Blumeae Balsamiferaes 40 parts of Herba Elsholtziae Ciliataes 45 parts
Wild vetch crow 35 parts is towards emperor's 30 parts of Herba pimpinellae diversifoliaes 30 parts.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3.
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and parts by weight are:
Radix Ginseng 95 parts of Cyrtomium fortunei J. Sm.s 85 parts of Radix Aconiti Coreanis 85 parts of Pseudobulbus Pholidotae Chinensis 80 parts
Radix Phytolaccae 75 parts of Testa sojae atricolors 75 parts of Herba Meliloti Suaveolentiss 75 parts of Uncaria sessilifructus Roxb 70 parts
Folium Nelumbinis 70 parts of Herba Crotalariae Ferrugineaes 60 parts of Herba Blumeae Balsamiferaes 60 parts of Herba Elsholtziae Ciliataes 60 parts
Wild vetch crow 50 parts is towards emperor's 40 parts of Herba pimpinellae diversifoliaes 40 parts.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data.
1, case selection:
Choose migraineur's case 100 example made a definite diagnosis altogether.
2, medicament selection:
Patient takes Chinese medicine preparation of the present invention, oral, every day 3 times, and the morning, noon and afternoon, respectively once each 27 days was a course for the treatment of, takes 2 courses for the treatment of.
3, efficacy determination:
(1) cure: headache and simultaneous phenomenon disappear, and sign is improved completely.
(2) effective: headache and simultaneous phenomenon disappear substantially, feature is improved obviously.
(3) effective: Headache attacks degree and simultaneous phenomenon alleviate to some extent, and feature makes moderate progress.
(4) invalid: headache and simultaneous phenomenon and feature are all without improving.
4, therapeutic effect:
In 100 routine patients, cure 45 examples (45%), effective 38 examples (38%), effective 14 examples (14%), invalid 3 examples (3%), cure rate 45%, total effective rate 97%.
Claims (5)
1. treat a migrainous Chinese medicine composition preparation, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Ginseng 60 ~ 95 parts of Cyrtomium fortunei J. Sm.s 55 ~ 85 parts of Radix Aconiti Coreanis 55 ~ 85 parts of Pseudobulbus Pholidotae Chinensis 50 ~ 80 parts
Radix Phytolaccae 45 ~ 75 parts of Testa sojae atricolors 45 ~ 75 parts of Herba Meliloti Suaveolentiss 45 ~ 75 parts of Uncaria sessilifructus Roxb 40 ~ 70 parts
Folium Nelumbinis 40 ~ 70 parts of Herba Crotalariae Ferrugineaes 35 ~ 60 parts of Herba Blumeae Balsamiferaes 30 ~ 60 parts of Herba Elsholtziae Ciliataes 30 ~ 60 parts
Wild vetch crow 25 ~ 50 parts is towards emperor's 20 ~ 40 parts of Herba pimpinellae diversifoliaes 20 ~ 40 parts.
2. treat migrainous Chinese medicine composition preparation according to the one described in claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Ginseng 60 parts of Cyrtomium fortunei J. Sm.s 55 parts of Radix Aconiti Coreanis 55 parts of Pseudobulbus Pholidotae Chinensis 50 parts
Radix Phytolaccae 45 parts of Testa sojae atricolors 45 parts of Herba Meliloti Suaveolentiss 45 parts of Uncaria sessilifructus Roxb 40 parts
Folium Nelumbinis 40 parts of Herba Crotalariae Ferrugineaes 35 parts of Herba Blumeae Balsamiferaes 30 parts of Herba Elsholtziae Ciliataes 30 parts
Wild vetch crow 25 parts is towards emperor's 20 parts of Herba pimpinellae diversifoliaes 20 parts.
3. treat migrainous Chinese medicine composition preparation according to the one described in claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Ginseng 80 parts of Cyrtomium fortunei J. Sm.s 70 parts of Radix Aconiti Coreanis 70 parts of Pseudobulbus Pholidotae Chinensis 65 parts
Radix Phytolaccae 60 parts of Testa sojae atricolors 60 parts of Herba Meliloti Suaveolentiss 65 parts of Uncaria sessilifructus Roxb 55 parts
Folium Nelumbinis 55 parts of Herba Crotalariae Ferrugineaes 45 parts of Herba Blumeae Balsamiferaes 40 parts of Herba Elsholtziae Ciliataes 45 parts
Wild vetch crow 35 parts is towards emperor's 30 parts of Herba pimpinellae diversifoliaes 30 parts.
4. treat migrainous Chinese medicine composition preparation according to the one described in claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Ginseng 95 parts of Cyrtomium fortunei J. Sm.s 85 parts of Radix Aconiti Coreanis 85 parts of Pseudobulbus Pholidotae Chinensis 80 parts
Radix Phytolaccae 75 parts of Testa sojae atricolors 75 parts of Herba Meliloti Suaveolentiss 75 parts of Uncaria sessilifructus Roxb 70 parts
Folium Nelumbinis 70 parts of Herba Crotalariae Ferrugineaes 60 parts of Herba Blumeae Balsamiferaes 60 parts of Herba Elsholtziae Ciliataes 60 parts
Wild vetch crow 50 parts is towards emperor's 40 parts of Herba pimpinellae diversifoliaes 40 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for migrainous Chinese medicine composition preparation, it is characterized in that: comprise following processing step:
(1) by Radix Ginseng, Cyrtomium fortunei J. Sm., Radix Aconiti Coreani, Pseudobulbus Pholidotae Chinensis, Radix Phytolaccae, Testa sojae atricolor, Herba Meliloti Suaveolentis, Uncaria sessilifructus Roxb,
Folium Nelumbinis, Herba Crotalariae Ferrugineae decontamination, be placed in container, adds the distilled water of 5 ~ 10 times, and 60 DEG C of lixiviates are after 3 ~ 5 hours, boil 1 ~ 2 hour, obtain extracting solution, filter, obtain filtrate, filtrate is concentrated into the extractum that relative density is 1 ~ 1.3, is cooled to room temperature, ultraviolet radiation sterilizing, for subsequent use;
(2) by Herba Blumeae Balsamiferae, Herba Elsholtziae Ciliatae, wild vetch crow, clean towards emperor, Herba pimpinellae diversifoliae, immerse the alcohol solution dipping 1 ~ 2 hour of 70% of 2 ~ 4 times amount, heating extraction 3 ~ 5 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the extractum of 1 ~ 1.3, be cooled to room temperature, ultraviolet radiation sterilizing, for subsequent use;
(3) by the extractum of step (1) gained, after fully mixing with the extractum of step (2) gained, can add or not add pharmaceutically acceptable adjuvant (disintegrating agent, binding agent etc.) and make various dosage form, as powder, granule, mixture etc., be the migrainous Chinese medicine composition preparation for the treatment of of the present invention.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108704055A (en) * | 2018-08-13 | 2018-10-26 | 杨彬 | A kind of Chinese medicine composition of Neurology treatment migraine |
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| CN103251821A (en) * | 2013-06-03 | 2013-08-21 | 肖变化 | Medicine for treating wind-heat headache and migraine headache and preparation method of medicine |
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| CN104189524A (en) * | 2014-09-10 | 2014-12-10 | 宁方波 | Traditional Chinese medicine composition for treating migraine |
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| CN103251821A (en) * | 2013-06-03 | 2013-08-21 | 肖变化 | Medicine for treating wind-heat headache and migraine headache and preparation method of medicine |
| CN103520555A (en) * | 2013-10-27 | 2014-01-22 | 周文华 | Drug for treatment of migraine |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108704055A (en) * | 2018-08-13 | 2018-10-26 | 杨彬 | A kind of Chinese medicine composition of Neurology treatment migraine |
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Application publication date: 20150826 |