CN103385973A - Miao medicine for curing liver cancer and preparation method thereof - Google Patents
Miao medicine for curing liver cancer and preparation method thereof Download PDFInfo
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- CN103385973A CN103385973A CN2013102913274A CN201310291327A CN103385973A CN 103385973 A CN103385973 A CN 103385973A CN 2013102913274 A CN2013102913274 A CN 2013102913274A CN 201310291327 A CN201310291327 A CN 201310291327A CN 103385973 A CN103385973 A CN 103385973A
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Abstract
The invention discloses a Miao medicine for curing liver cancer, and belongs to the field of medicinal preparation. The Miao medicine comprises the main drugs and the auxiliary drug. The main drugs are composed of following medicinal materials in parts by weight: 30 to 40 parts of heydyotis, 30 to 40 parts of barbat skullcap, 20 to 25 parts of honeysuckle flower, 20 to 25 parts of virgate wormwood, 20 to 25 parts of hairyvein agrimony, 10 to 15 parts of radix astragali, 15 to 20 parts of solanum nigrum, 15 to 20 parts of gentrin knotweed, 20 to 25 parts of spina gleditsiae, 12 to 16 parts of banksia rose, 20 to 25 parts of salvia chinensis and 20 to 25 parts of prunella vulgaris. The auxiliary drug is 6 to 8 parts of dried toad skin. The preparation method comprises following steps: cleaning and washing the medicinal materials mentioned above, drying, grinding, disinfecting, mixing according to the formula ratio, putting into a pottery container, or a cooper pot, or a wood barrel, or a cement pool, adding water to impregnate the materials, introducing steam gas to heat the water, extracting the effective components, filtering, making the medicinal liquid into a extract, drying, then mixing with the auxiliary drug namely dried toad skin, grinding the mixture into powder, finally pressing into tablets or packaging into capsules, and obtaining the product. The Miao medicine has an effective rate over 70% and is suitable for curing liver cancer patients.
Description
Technical field
The present invention relates to medicine, relate to furthermore the medicine of Hepatoma therapy.
Background technology
Hepatocarcinoma refers to betide the malignant tumor of liver, comprises two kinds of primary hepatocarcinoma and secondary liver cancers, and mostly the hepatocarcinoma of the daily theory of people is primary hepatocarcinoma if referring to.Primary hepatocarcinoma is one of modal malignant tumor clinically, and according to recent statistics, the annual new liver cancer patient in the whole world approximately 600,000, occupy the 5th of malignant tumor.Primary hepatocarcinoma can be divided into Hepatocellular carcinoma, intrahepatic cholangiocarcinoma and mixed carcinoma of liver by cell typing.
In recent years, the medicine that develops Chinese herbs for treating liver cancer is paid close attention to by people always.Existing hundreds of of Chinese patent application part, recent years, applications increased severely.According to incompletely statistics, there were 8 in 2004, had 4 in 2005, had 3 in 2006, had 7 in 2007, had 4 in 2008, reached 10 in 2009, be increased to 10 in 2010, be increased to 12 in 2011, reached 17 in 2012.nearest application part has: No. 201310043777.1 " treatment acute, chronic hepatitis, the Chinese medicine composition of hepatosplenomegaly and inhibition hepatocarcinoma ", number 201310071291.9 " Chinese medicine composition of a kind of Hepatoma therapy and preparation method thereof ", number 201310080231.3 " a kind of Chinese medicine composition with anti-hepatocarcinoma and pulmonary carcinoma effect ", number 201310086007.5 " Chinese medicine composition of a kind of anti-pulmonary carcinoma and hepatocarcinoma ", number 201310007878.3 " a kind of Chinese medicine for the treatment of primary hepatocarcinoma " etc.These medicines respectively have its characteristics and curative effect, but for liver cancer patient, it is exactly Gospel that more effective medicine produces.
There is long national culture in the Miao ethnic group that mainly is distributed in Southwestern China, and Seedling doctor Miao Ethnomedicine is exactly the part of Miao ethnic group's culture, and many proved recipes evident in efficacy are wherein arranged.But relevant report and the patent application of the Miao Ethnomedicine of Hepatoma therapy are arranged not yet up to now.
Summary of the invention
The object of the present invention is to provide a kind of Miao Ethnomedicine of Hepatoma therapy, be the enteritis patient service, the promotion people's is healthy.
Another purpose of the present invention is to provide the method for making of above-mentioned Miao Ethnomedicine, enables practical application.
The Miao Ethnomedicine of the Hepatoma therapy that the inventor provides is made by principal agent and the accessory drugs of following quality proportioning:
Principal agent: Herba Hedyotidis Diffusae 30～40, Herba Scutellariae Barbatae 30～40, Flos Lonicerae 20～25, Artemisia anethoicles Mattf 20～25, Herba Agrimoniae 20～25, the Radix Astragali 10～15, Herba Solani Nigri 15～20, Rhizoma Polygoni Cuspidati 15～20, Fructus Gleditsia system 20～25, the Radix Aucklandiae 12～16, Herba Salviae Chinensis 20～25, Spica Prunellae 20～25;
Accessory drugs: 6～8.
The preferred mass proportioning of this Miao Ethnomedicine is:
Herba Hedyotidis Diffusae 35, Herba Scutellariae Barbatae 35, Flos Lonicerae 22, Artemisia anethoicles Mattf 22, Herba Agrimoniae 22, the Radix Astragali 12, Herba Solani Nigri 18, Rhizoma Polygoni Cuspidati 16, Fructus Gleditsia system 22, the Radix Aucklandiae 14, Herba Salviae Chinensis 22, Spica Prunellae 22;
Dry Bufo siccus skin 7.
In above-mentioned medical material,
Herba Hedyotidis DiffusaeFor the Maguireothamnus speciosus Herba Hedyotidis Diffusae (
Oldenlandia diffusa) whole herb with root, bitter but sweet flavor, warm in nature, the effect (see the new medical college in Jiangsu compile " Chinese medicine voluminous dictionary " 754 pages) of heat clearing away, dampness removing, detoxifcation is arranged;
Herba Scutellariae BarbataeFor the portulacaceous plant Herba Scutellariae Barbatae (
Portulaca grandiflora) herb, bitter in the mouth, cold in nature, heat clearing away, detoxicating functions (seeing " Chinese crude drug voluminous dictionary " 779 pages) are arranged;
Flos LoniceraeFor caprifoliaceae plant Radix Ophiopogonis (
Lonicera japonica) alabastrum, sweet in the mouth, cold in nature, can heat-clearing and toxic substances removing (seeing " Chinese medicine voluminous dictionary " 1403 pages);
Herba Artemisiae Scopariae, i.e. Herba Artemisiae Scopariae, for the feverfew Herba Artemisiae Scopariae (
Artemisia capillaris) young young stem and leaf, bitter in the mouth is hot, and is cool in nature, can clearing away heat-damp and promoting diuresis (seeing " Chinese medicine voluminous dictionary " 1588 pages);
Herba AgrimoniaeFor the rosaceous plant Radix Agrimoniae (
Agrimonia pilosa) herb, acrid in the mouth is bitter, property is flat, can stop blooding, stomach invigorating (seeing " Chinese medicine voluminous dictionary " 665 pages);
The Radix AstragaliFor the leguminous plant Radix Astragali (
Astragalus membranaceus) root, sweet in the mouth, slightly warm in nature, can stomach reinforcing consolidating superficial resistance, inducing diuresis to remove edema, invigorating the spleen and replenishing QI (seeing " Chinese medicine voluminous dictionary " 2036 pages); Herba Solani Nigri be the plant of Solanaceae Herba Solani Nigri (
Solanum nigrum) herb, bitter in the mouth, cold in nature, can heat clearing away, (seeing " Chinese medicine voluminous dictionary " 630 pages) detoxifies, invigorates blood circulation, subsides a swelling;
Rhizoma Polygoni CuspidatiFor the polygonaceae plant Rhizoma Polygoni Cuspidati (
Polygonum cuspidatum) rhizome, bitter in the mouth, property is flat, can dispel the wind, dampness removing, removing blood stasis with potent drugs, (seeing " Chinese medicine voluminous dictionary " 1329 pages) stimulates the menstrual flow;
Spina GleditsiaeFor the leguminous plant Fructus Gleditsia (
Gleditsia sinensis) Spina jujubae, acrid in the mouth, warm in nature, can search wind, toxin expelling, the detumescence, draw out the pus (seeing " Chinese medicine voluminous dictionary " 1145 pages);
The Radix Aucklandiae, for the feverfew Saussurea lappa Clarke (
Saussurea lappa) root, acrid in the mouth is bitter, and is warm in nature, can circulation of qi promoting, pain relieving, warming middle-JIAO for easing the stomach (seeing " Chinese medicine voluminous dictionary " 353 pages);
Herba Salviae ChinensisFor the labiate Herba Salviae Chinensis (
Salvia chinensis) herb, bitter in the mouth is hot, property is flat, can control dysphagic, phlegm dyspnea, hepatitis (seeing " Chinese medicine voluminous dictionary " 597 pages);
Spica PrunellaeFor the labiate Spica Prunellae (
Prunella vuigaris) herb, acrid in the mouth is bitter, and is cold in nature, can liver heat removing heat radiation (seeing " Chinese medicine voluminous dictionary " 1827 pages).
Accessory drugs:
The dry Bufo siccus skin, for Bufonidae animal Bufo siccus (
Bufo bufo gargarizans) skin, acrid in the mouth, cool in nature, poisonous, Neng Po Disorder knot, row water are wet, removing toxic substances, analgesic therapy (seeing " Chinese medicine voluminous dictionary " 2717 pages).
Above-mentioned medical material should meet " the regulation in one one of Chinese pharmacopoeia nineteen ninety-five version under each medical material item.
The method for making of the Miao Ethnomedicine of Hepatoma therapy of the present invention is that above-mentioned 12 flavor principal agent medical materials are cleaned respectively, uses hot-air seasoning, is ground into chunky shape, then uses disinfection by ultraviolet light; After pressing again formula proportion and mixing, put into the pond that pottery or copper tank or wooden barrel or cement is built into and add water retting, and pass into steam heated 3 times, until wherein active ingredient proposes substantially; Filter, the medicinal liquid that obtains is made extractum; Fire drying in using again, then with accessory drugs dry Bufo siccus skin co-grinding, grind to form 60 order powder; Pharmaceutical technology routinely, be pressed into tablet or incapsulate finally, and every 1g or every 1g, obtain tablet or capsule.
The above-mentioned pharmaceutical technology that is pressed into tablet comprises: 1. the 60 order powder that make are added adjuvant, main adjuvant is the adhesive modified starch, mix homogeneously; 2. add water as wetting agent in mixed powder, make soft material; 3. soft material extruding is sieved, granulation; 4. granule is through super-dry, make its moisture be fit to and evenly, grain graininess is suitable; 5. dried particles, through check, confirms to meet the requirement of tablet; 6. extrude tablet with Chong Yashi or rotary tablet machine, what be up to the standards is finished product.
The pharmaceutical technology of above-mentioned capsule comprises: 1. prepare or buy capsulae vacuus take gelatin as primary raw material; The 60 order powder that 2. will make are crossed sieve No. 6, and the fine powder that obtains is standby; 3. enter soft capsule with the artificial medicated powder of loading, or with the automatic filling machine medicated powder of packing into; 4. effective ingredient and the quality of medicated powder are tested, qualified rear glue with gelatin, in the sealing of capsule capping place, obtains finished product.
The inventor points out: this Miao Ethnomedicine also can be prepared into any peroral dosage form commonly used with conventional method of Chinese medicinal.No matter which kind of dosage form, all must deposit according to the relevant regulations of drug stock control.
The Miao Ethnomedicine using method of Hepatoma therapy is oral, 2 times on the one, and each 4-5 sheet/grain, warm water delivery service.
Miao Ethnomedicine of the present invention be on the basis of summing up forefathers' secret recipe in addition perfect, supplement, through the formula of clinical use checking, therapeutic effect is good.Accept in recent years liver cancer patient 11 people for medical treatment, cure 7 people, 1 people is effective, and 3 people are invalid.Below the model case of some treatments:
Case one: Li mao mao, man, 58 years old.Found hepatalgia, and be off one's feed in 2009.Be hepatocarcinoma through Guizhou hospital.Through taking Miao Ethnomedicine of the present invention half a year, the state of an illness is clearly better, and serve on 1 year, and ill symptoms disappears.After 2 years, with anti-, the people is also alive.
Case two: second child Xu, man, 61 years old, people from Qianxi County, Guizhou Province.In January, 2007, the patient feels hepatalgia, after develop into the symptoms such as enlarged abdomen, hurt like hell, be hepatocarcinoma through the West China Hospital inspection.Once hospitalization, took multiple Western medicine and Chinese medicine, and was all invalid.Upon somebody's introduction, take medicine of the present invention, 4 months, hepatalgia took a turn for the better to some extent, and abdominal part diminishes, and serve on 8 months, and pain, enlarged abdomen phenomenon disappear, as the normal person.After 3 years, with anti-, the people is also alive, the work of normally going to work.
Case three: Luo Xiaoman, female, 39 years old, people from Zunyi City, Guizhou Province.In July, 2012, there is pain in Finding case liver, but diet is normal.At many examination in hospital such as Chongqing, Zun Yi, there is a shade in liver,, through changing inspection, is hepatocarcinoma.More than hospitalization March, poor effect, after being introduced, took Miao Ethnomedicine of the present invention 3 months, and pain disappears, and serve on half a year, goes hospital's check, and all are normal., with anti-, can also normally go to work so far.
Miao Ethnomedicine effective percentage of the present invention reaches more than 70%.Be applicable to the Hepatoma therapy patient.
The specific embodiment
Embodiment prepares the Miao Ethnomedicine of Hepatoma therapy of the present invention:
Above-mentioned 12 flavor medical materials are cleaned respectively, used hot-air seasoning, be ground into chunky shape, then use disinfection by ultraviolet light; Get Herba Hedyotidis Diffusae 35g, Herba Scutellariae Barbatae 35g, Flos Lonicerae 22g, Artemisia anethoicles Mattf 22g, Herba Agrimoniae 22g, Radix Astragali 12g, Herba Solani Nigri 18g, Rhizoma Polygoni Cuspidati 16g, Fructus Gleditsia 22g processed, Radix Aucklandiae 14g, Herba Salviae Chinensis 22g, Spica Prunellae 22g; After mixing, put into terrine and add water retting, and pass into steam heated, through chemically examining till wherein active ingredient proposes substantially; Filter, the medicinal liquid that obtains is made extractum; Fire drying in using again, then with accessory drugs dry Bufo siccus skin 7g co-grinding, grind to form 60 order powder; Pharmaceutical technology routinely, be pressed into tablet or incapsulate finally, and every 1g or every 1g, obtain tablet or capsule.
Claims (3)
1. the Miao Ethnomedicine of a Hepatoma therapy is characterized in that this Miao Ethnomedicine made by principal agent and the accessory drugs of following quality proportioning:
Principal agent: Herba Hedyotidis Diffusae 30～40, Herba Scutellariae Barbatae 30～40, Flos Lonicerae 20～25, Artemisia anethoicles Mattf 20～25, Herba Agrimoniae 20～25, the Radix Astragali 10～15, Herba Solani Nigri 15～20, Rhizoma Polygoni Cuspidati 15～20, Fructus Gleditsia system 20～25, the Radix Aucklandiae 12～16, Herba Salviae Chinensis 20～25, Spica Prunellae 20～25;
Accessory drugs: dry Bufo siccus skin 6～8.
2. Miao Ethnomedicine as claimed in claim 1 is characterized in that this Miao Ethnomedicine made by principal agent and the accessory drugs of following quality proportioning:
Principal agent: Herba Hedyotidis Diffusae 35, Herba Scutellariae Barbatae 35, Flos Lonicerae 22, Artemisia anethoicles Mattf 22, Herba Agrimoniae 22, the Radix Astragali 12, Herba Solani Nigri 18, Rhizoma Polygoni Cuspidati 16, Fructus Gleditsia system 22, the Radix Aucklandiae 14, Herba Salviae Chinensis 22, Spica Prunellae 22;
Accessory drugs: dry Bufo siccus skin 7.
3., as the method for making of Miao Ethnomedicine as described in one of claim 1 or 2, it is characterized in that above-mentioned 12 flavor principal agent medical materials are cleaned respectively, use hot-air seasoning, be ground into chunky shape, then use disinfection by ultraviolet light; After pressing again formula proportion and mixing, put into the pond that pottery or copper tank or wooden barrel or cement is built into and add water retting, and pass into steam heated 3 times, until wherein active ingredient proposes substantially; Filter, the medicinal liquid that obtains is made extractum; Fire drying in using again, then with accessory drugs dry Bufo siccus skin co-grinding, grind to form 60 order powder; Pharmaceutical technology routinely, be pressed into tablet or incapsulate finally, and every 1g or every 1g, obtain tablet or capsule.
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Cited By (2)
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| CN105327267A (en) * | 2015-10-22 | 2016-02-17 | 纪辉 | Traditional Chinese medicine liquor for treating tumors and preparation method of traditional Chinese medicine liquor for treating tumors |
| CN108245607A (en) * | 2018-04-11 | 2018-07-06 | 曾祖荫 | A kind of seedling medicine for treating tumour and preparation method thereof |
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| CN101670071A (en) * | 2009-09-25 | 2010-03-17 | 卢速江 | Traditional Chinese medicine preparation for treating cancer and preparation method thereof |
| CN101700386A (en) * | 2009-11-12 | 2010-05-05 | 范先明 | Traditional Chinese medicine composition resistant to liver cancer and medicine coat thereof |
| CN102349982A (en) * | 2011-10-28 | 2012-02-15 | 尹留风 | Traditional Chinese medicine composition for cancer rehabilitation |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105327267A (en) * | 2015-10-22 | 2016-02-17 | 纪辉 | Traditional Chinese medicine liquor for treating tumors and preparation method of traditional Chinese medicine liquor for treating tumors |
| CN108245607A (en) * | 2018-04-11 | 2018-07-06 | 曾祖荫 | A kind of seedling medicine for treating tumour and preparation method thereof |
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| CN103385973B (en) | 2015-04-15 |
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