CN103385894B - Buccal tablets prepared from ganoderma broken-down wall spore powder - Google Patents
Buccal tablets prepared from ganoderma broken-down wall spore powder Download PDFInfo
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- CN103385894B CN103385894B CN201310321083.XA CN201310321083A CN103385894B CN 103385894 B CN103385894 B CN 103385894B CN 201310321083 A CN201310321083 A CN 201310321083A CN 103385894 B CN103385894 B CN 103385894B
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Abstract
The invention relates to a buccal tablet prepared from ganoderma broken-down wall spore powder, and belongs to the technical field of medical and health-care foods. The buccal tablet is prepared from the following components by weight percent: 40-60% of a main ingredient ganoderma broken-down wall spore powder, 30-50% of fillers isomaltitol and xylitol (a ratio of isomaltitol to xylitol is 1:1), 1-2% of an aromatic mint oil, 0.5-1.5% of a wetting agent hydroxyl propyl cellulose (HPC), 1.5-2.5% of a binder ethylecellulose (EC), 0.5-1.5% of a disintegrating agent polyvinylpyrrolidone (PVP), 0.5-0.8% of a corrigent Aspartame and a tabletting lubricant: 0.5-1% of a tabletting lubricant. The ganoderma broken-down wall spore powder buccal tablets provided by the invention have the beneficial effects that ganoderma spore powder is convenient to carry and take and is not easy to deteriorate after long storage, the unique taste of the ganoderma spore powder is maintained, and the buccal tablet is convenient for a human body can conveniently uptake nutritional ingredients.
Description
Technical field
The invention belongs to medicine and technical field of health care food, particularly relate to a kind of Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet.
Background technology
Ganoderma as the valuable ingredient of Chinese medicine in Chinese traditional medicine treasure-house, be widely used in curing the disease by Chinese medicine practitioner over the past thousands of years, health preserving, in the prescription such as life lengthening.Ganoderma spore powder is that Ganoderma sporophore is when growing into the maturation period, the very tiny Powdered seed erupting out from Ganoderma sporophore, for breeding the next generation, under certain temperature, damp condition, the Ganoderma sporophore of Ganoderma spore powder germination and growth Cheng Xin.Ganoderma spore powder individual particle is that naked eyes institute is invisible, and individual particle size only has 6 to 8 microns, is equivalent to a thirtieth of hair diameter.Ganoderma spore powder is equivalent to the pollen of flower, the fruit of fruit tree.Ganoderma spore powder particles outer wrapping the chitin shell of one deck hard, affect absorption of human body, be conducive to absorption of human body after broken chitin shell, if Ganoderma spore powder is chronically exposed in air and deposits perishable in addition, human body also can be caused to be difficult to absorb effective nutritional labeling.
Summary of the invention
According to above deficiency, the object of this invention is to provide a kind of Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet, facilitate carrying and taking of Ganoderma spore powder, solve Ganoderma spore powder long-term storage and guarantee the quality, keep Ganoderma spore powder unique taste, facilitate the more effective absorption nutritional labeling of human body.
To achieve these goals, the technical solution used in the present invention is: a kind of Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet, Sporoderm-broken Ganoderma Lucidum Spore powder is made buccal tablet, and the raw material mass mixture ratio of described Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet is: 1, major ingredient: Sporoderm-broken Ganoderma Lucidum Spore powder, content 40%-60%; 2, filler: hydroxyl isomaltulose and xylitol, the two proportioning is 1: 1, content 30%-50%; 3, aromatic: Oleum menthae, content 1%-2%; 4, wetting agent: hydroxypropyl cellulose (HPC), content 0.5%-1.5%; 5, binding agent: ethyl cellulose (EC), content 1.5%-2.5%; 6, disintegrating agent: polyvinylpyrrolidone (PVP), content 0.5%-1.5%; 7, correctives: aspartame, 0.5%-0.8%; 8, tableting lubricant: magnesium stearate, content 0.5%-1%; Described Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet fabrication processing is: raw material Ganoderma spore powder quality inspection-cleaning-oven dry-lucidium spore powder wall breaking-oven dry-batching-pelletize again-tabletting-sterilizing-packaging; Detailed fabrication processing is the quality inspection of (1) raw material Ganoderma spore powder: described in the Pharmacopoeia of the People's Republic of China: lucidum variety has kind more than 100, what can be used as medicine only has Ganoderma and Ganoderma lucidum (Leyss. Ex Fr.) Karst., and this Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet raw material is chosen Dabie Mountain and originated in red ganoderma or Ganoderma spore powder that Ganoderma sinense Zhao Xu et Zhang produces; To choose in then to 2 year produce Ganoderma spore powder, all spore powders all need be deposited in icebox in cold preservation; The required free from extraneous odour of Ganoderma spore powder, without rotting to go mouldy, total plate count meets national standard; Spore powder is inspected by random samples, spore powder full grains under microscope, and special-shaped granule is less than 5%-10%; In raw material, non-spore powder impurity is less than 1%-5%; (2) clean: after the quality inspection of raw material spore powder completes, start cleaning, use the cleaning of raw material cleaning robot; Water for cleaning for purifying waste water, water temperature 20-30 degree Celsius; Scavenging period is 10-20 minute, and with uniform stirring; After having washed, use microporous filter machine to complete raw material and be separated with water; Re-use centrifuge and be separated residue insoluble in water impurity; (3) dry: after impurity is rejected in raw material cleaning, carry out oven dry operation, use dehydrator, temperature 50-60 degree Celsius; Raw material stack thickness is even, not higher than 20-30 millimeter; Drying time is 20-40 minute, within every ten minutes, turns over once whole; (4) lucidium spore powder wall breaking: Ganoderma spore powder starts breaking cellular wall after drying, and selects import pottery to roll rod, carries out rolling breaking cellular wall; For ensureing sporoderm-broken rate, once roll raw material weight not higher than 2 kilograms-3 kilograms; The time of rolling is 40-60 minute; (5) again dry: bake out temperature 40-60 degree Celsius; Raw material stack thickness is even, must not higher than 20-30 millimeter; Drying time is 5-10 minute; (6) prepare burden: the exosporium-broken spore powder raw material after oven dry mixes according to proportion scale and filler, wetting agent, binding agent, correctives, disintegrating agent uniform stirring, is uniformly mixed time 20-40 minute; (7) pelletize: after having prepared burden, crosses 10 order-20 order stainless (steel) wires with oscillating granulator and granulates, dry, with 10 order-20 order stainless (steel) wire granulate, obtain dry granule; (8) tabletting: feed particles, through row tabletting, proportionally calls in aromatic, tableting lubricant, tablet machine uses mould bore to be 8-15 millimeter, and sheeting thickness is 4-6 millimeter; Diameter 8-15 millimeter, the heavy 200-400 milligram of sheet; (9) sterilizing: through ultraviolet radiation 10-30 second after tabletting completes; (10) pack: the buccal tablet granule after sterilizing is packed, use streamline packaging; Be packaged as and pack, all indexs perform according to national related pharmaceutical rules and regulations.
The invention has the beneficial effects as follows: facilitate carrying and taking of Ganoderma spore powder, long-term storage is not perishable, keep Ganoderma spore powder unique taste, facilitate the more effective absorption nutritional labeling of human body.
Detailed description of the invention
Further the present invention is illustrated below in conjunction with detailed description of the invention;
Embodiment 1: a kind of Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet, makes buccal tablet by Sporoderm-broken Ganoderma Lucidum Spore powder, and described Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet raw material mass mixture ratio is: Sporoderm-broken Ganoderma Lucidum Spore powder, 50%; Hydroxyl isomaltulose 22%, xylitol 22%; Oleum menthae 1%; Hydroxypropyl cellulose (HPC), 1%; Ethyl cellulose (EC), 2%; Polyvinylpyrrolidone (PVP), 1%; Aspartame, 0.5%; Magnesium stearate, content 0.5%.Raw material Ganoderma spore powder quality inspection-cleaning-oven dry-lucidium spore powder wall breaking-oven dry-batching-pelletize again-tabletting-sterilizing-packaging; Idiographic flow is the quality inspection of (1) raw material Ganoderma spore powder: this Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet raw material is chosen Dabie Mountain and originated in red ganoderma or Ganoderma sinense Zhao Xu et Zhang is produced Ganoderma spore powder; To choose in then to 2 year produce Ganoderma spore powder, all spore powders all need be deposited in icebox in cold preservation; The required free from extraneous odour of Ganoderma spore powder, without rotting to go mouldy, total plate count meets national standard; Spore powder is inspected by random samples, spore powder full grains under microscope, and special-shaped granule is less than 5%-10%; In raw material, non-spore powder impurity is less than 1%-5%; (2) clean: after the quality inspection of raw material spore powder completes, start cleaning, use the cleaning of raw material cleaning robot; Water for cleaning for purifying waste water, water temperature 20-30 degree Celsius; Scavenging period is 10-20 minute, and with uniform stirring; After having washed, use microporous filter machine to complete raw material and be separated with water; Re-use centrifuge and be separated residue insoluble in water impurity; (3) dry: after impurity is rejected in raw material cleaning, carry out oven dry operation, use dehydrator, temperature 50-60 degree Celsius; Raw material stack thickness is even, not higher than 20-30 millimeter; Drying time is 20-40 minute, within every ten minutes, turns over once whole; (4) lucidium spore powder wall breaking: Ganoderma spore powder starts breaking cellular wall after drying, and selects import pottery to roll rod, carries out rolling breaking cellular wall; For ensureing sporoderm-broken rate, once roll raw material weight not higher than 2 kilograms-3 kilograms; The time of rolling is 40-60 minute; (5) again dry: bake out temperature 40-60 degree Celsius; Raw material stack thickness is even, must not higher than 20-30 millimeter; Drying time is 5-10 minute; (6) prepare burden: the exosporium-broken spore powder raw material after oven dry mixes according to proportion scale and filler, wetting agent, binding agent, correctives, disintegrating agent uniform stirring, is uniformly mixed time 20-40 minute; (7) pelletize: after having prepared burden, crosses 10 order-20 order stainless (steel) wires with oscillating granulator and granulates, dry, with 10 order-20 order stainless (steel) wire granulate, obtain dry granule; (8) tabletting: feed particles, through row tabletting, proportionally calls in aromatic, tableting lubricant, tablet machine uses mould bore to be 8-15 millimeter, and sheeting thickness is 4-6 millimeter; Diameter 8-15 millimeter, the heavy 200-400 milligram of sheet; (9) sterilizing: through ultraviolet radiation 10-30 second after tabletting completes; (10) pack: the buccal tablet granule after sterilizing is packed, use streamline packaging; Be packaged as and pack, all indexs perform according to national related pharmaceutical rules and regulations.
Embodiment 2: a kind of Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet, makes buccal tablet by Sporoderm-broken Ganoderma Lucidum Spore powder, and described Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet raw material mass mixture ratio is: Sporoderm-broken Ganoderma Lucidum Spore powder, 60%; Hydroxyl isomaltulose 17%, xylitol 17%; Oleum menthae 1%; Hydroxypropyl cellulose (HPC), 1%; Ethyl cellulose (EC), 2.5%; Polyvinylpyrrolidone (PVP), 0.5%; Aspartame, 0.5%; Magnesium stearate, content 0.5%.Raw material Ganoderma spore powder quality inspection-cleaning-oven dry-lucidium spore powder wall breaking-oven dry-batching-pelletize again-tabletting-sterilizing-packaging, concrete processing as described in Example 1.
Embodiment 3: a kind of Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet, makes buccal tablet by Sporoderm-broken Ganoderma Lucidum Spore powder, and described Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet raw material mass mixture ratio is: Sporoderm-broken Ganoderma Lucidum Spore powder, 44%; Hydroxyl isomaltulose 25%, xylitol 25%; Oleum menthae 1%; Hydroxypropyl cellulose (HPC), 1%; Ethyl cellulose (EC), 1.5%; Polyvinylpyrrolidone (PVP), 1.5%; Aspartame, 0.5%; Magnesium stearate, content 0.5%.Raw material Ganoderma spore powder quality inspection-cleaning-oven dry-lucidium spore powder wall breaking-oven dry-batching-pelletize again-tabletting-sterilizing-packaging, concrete processing as described in Example 1.
Last it is noted that obviously, above-described embodiment is only for example of the present invention is clearly described, and the restriction not to embodiment.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description, thus the apparent change of extending out or variation be still among protection scope of the present invention.
Claims (1)
1. a Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet, makes buccal tablet by Sporoderm-broken Ganoderma Lucidum Spore powder, and the raw material mass mixture ratio of described Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet is: 1, major ingredient: Sporoderm-broken Ganoderma Lucidum Spore powder, content 40%-60%; 2, filler: hydroxyl isomaltulose and xylitol, the two proportioning is 1: 1, content 30%-50%; 3, aromatic: Oleum menthae, content 1%-2%; 4, wetting agent: hydroxypropyl cellulose (HPC), content 0.5%-1.5%; 5, binding agent: ethyl cellulose (EC), content 1.5%-2.5%; 6, disintegrating agent: polyvinylpyrrolidone (PVP), content 0.5%-1.5%; 7, correctives: aspartame, 0.5%-0.8%; 8, tableting lubricant: magnesium stearate, content 0.5%-1%; Be characterised in that described Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet fabrication processing is: raw material Ganoderma spore powder quality inspection-cleaning-oven dry-lucidium spore powder wall breaking-oven dry-batching-pelletize again-tabletting-sterilizing-packaging; Detailed fabrication processing is (1) raw material Ganoderma spore powder quality inspection: this Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet raw material is chosen Dabie Mountain and originated in red ganoderma or Ganoderma sinense Zhao Xu et Zhang is produced Ganoderma spore powder; To choose in then to 2 year produce Ganoderma spore powder, all spore powders all need be deposited in icebox in cold preservation; The required free from extraneous odour of Ganoderma spore powder, without rotting to go mouldy, total plate count meets national standard; Spore powder is inspected by random samples, spore powder full grains under microscope, and special-shaped granule is less than 5%-10%; In raw material, non-spore powder impurity is less than 1%-5%; (2) clean: after the quality inspection of raw material spore powder completes, start cleaning, use the cleaning of raw material cleaning robot; Water for cleaning for purifying waste water, water temperature 20-30 degree Celsius; Scavenging period is 10-20 minute, and with uniform stirring; After having washed, use microporous filter machine to complete raw material and be separated with water; Re-use centrifuge and be separated residue insoluble in water impurity; (3) dry: after impurity is rejected in raw material cleaning, carry out oven dry operation, use dehydrator, temperature 50-60 degree Celsius; Raw material stack thickness is even, not higher than 20-30 millimeter; Drying time is 20-40 minute, within every ten minutes, turns over once whole; (4) lucidium spore powder wall breaking: Ganoderma spore powder starts breaking cellular wall after drying, and selects import pottery to roll rod, carries out rolling breaking cellular wall; For ensureing sporoderm-broken rate, once roll raw material weight not higher than 2 kilograms-3 kilograms; The time of rolling is 40-60 minute; (5) again dry: bake out temperature 40-60 degree Celsius; Raw material stack thickness is even, must not higher than 20-30 millimeter; Drying time is 5-10 minute; (6) prepare burden: the exosporium-broken spore powder raw material after oven dry mixes according to proportion scale and filler, wetting agent, binding agent, correctives, disintegrating agent uniform stirring, is uniformly mixed time 20-40 minute; (7) pelletize: after having prepared burden, crosses 10 order-20 order stainless (steel) wires with oscillating granulator and granulates, dry, with 10 order-20 order stainless (steel) wire granulate, obtain dry granule; (8) tabletting: feed particles, through row tabletting, proportionally calls in aromatic, tableting lubricant, tablet machine uses mould bore to be 8-15 millimeter, and sheeting thickness is 4-6 millimeter; Diameter 8-15 millimeter, the heavy 200-400 milligram of sheet; (9) sterilizing: through ultraviolet radiation 10-30 second after tabletting completes; (10) pack: the buccal tablet granule after sterilizing is packed, use streamline packaging; Be packaged as and pack, all indexs perform according to national related pharmaceutical rules and regulations.
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Families Citing this family (11)
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| CN103932000B (en) * | 2014-04-30 | 2015-11-18 | 吉林市盛誉美康科技有限公司 | A kind of Reishi sporule powder chewable tablet of compound Oilgosaccharkdes and preparation technology thereof |
| CN104323230B (en) * | 2014-11-19 | 2016-03-16 | 清源 | Broken wall ferfas lozenge and preparation method thereof |
| CN104820073A (en) * | 2015-05-05 | 2015-08-05 | 李朝谦 | Method for quickly and simply detecting impurities of ganoderma lucidum spore powder |
| CN105767999A (en) * | 2016-03-17 | 2016-07-20 | 孙继勇 | Buccal tablet containing wall-broken ganoderma lucidum spore powder, honey and propolis and production method thereof |
| CN106307498A (en) * | 2016-08-23 | 2017-01-11 | 安徽阳光药业有限公司 | Ganoderma lucidum lozenge and preparation method thereof |
| CN106581084A (en) * | 2016-12-15 | 2017-04-26 | 湖南中健欣元生物科技有限公司 | Ganoderma broken-down wall pellet lozenge and preparing method thereof |
| CN109480271A (en) * | 2017-09-11 | 2019-03-19 | 孙继勇 | A kind of preparation method of ganoderma spove powder dripping pill |
| CN108968032A (en) * | 2018-08-23 | 2018-12-11 | 安徽德源堂生物科技有限公司 | A kind of preprocess method of lucidum spore powder |
| CN112021555A (en) * | 2020-08-31 | 2020-12-04 | 山东省农业科学院农产品研究所 | Ganoderma lucidum spore powder tablet and preparation method thereof |
| CN114631598A (en) * | 2022-04-09 | 2022-06-17 | 吉林省爱康寿生物科技有限公司 | Non-waste preparation treatment process for industrialization of cut-log ganoderma lucidum |
| CN115068424A (en) * | 2022-07-15 | 2022-09-20 | 中农弘仁纳米生物科技(北京)有限公司 | Preparation method and application of nanoscale wall-broken ganoderma lucidum spore powder |
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| CN100377735C (en) * | 2006-04-26 | 2008-04-02 | 李发有 | Ganoderma lucidum buccal tablet |
| CN100508956C (en) * | 2006-05-24 | 2009-07-08 | 南京中科集团股份有限公司 | Ganoderma spore tablet and preparation process thereof |
| CN101683325A (en) * | 2008-09-28 | 2010-03-31 | 北京华素制药股份有限公司 | Cydiodine buccal tablets and preparation method thereof |
| CN101828711A (en) * | 2010-04-30 | 2010-09-15 | 云南瑞升烟草技术（集团）有限公司 | Myrobalan-containing food |
| CN102919852A (en) * | 2012-11-12 | 2013-02-13 | 沈阳信达信息科技有限公司 | Ganoderma lozenge |
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