CN103385894A - Buccal tablets prepared from ganoderma broken-down wall spore powder - Google Patents
Buccal tablets prepared from ganoderma broken-down wall spore powder Download PDFInfo
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- CN103385894A CN103385894A CN201310321083XA CN201310321083A CN103385894A CN 103385894 A CN103385894 A CN 103385894A CN 201310321083X A CN201310321083X A CN 201310321083XA CN 201310321083 A CN201310321083 A CN 201310321083A CN 103385894 A CN103385894 A CN 103385894A
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- 239000000843 powder Substances 0.000 title claims abstract description 92
- 241000222336 Ganoderma Species 0.000 title claims abstract description 47
- 239000006189 buccal tablet Substances 0.000 title claims abstract description 35
- 229940046011 buccal tablet Drugs 0.000 claims abstract description 33
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims abstract description 12
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims abstract description 12
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims abstract description 12
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims abstract description 7
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000002278 tabletting lubricant Substances 0.000 claims abstract description 7
- 239000000811 xylitol Substances 0.000 claims abstract description 7
- 235000010447 xylitol Nutrition 0.000 claims abstract description 7
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims abstract description 7
- 229960002675 xylitol Drugs 0.000 claims abstract description 7
- 108010011485 Aspartame Proteins 0.000 claims abstract description 6
- 125000003118 aryl group Chemical group 0.000 claims abstract description 6
- 239000000605 aspartame Substances 0.000 claims abstract description 6
- 235000010357 aspartame Nutrition 0.000 claims abstract description 6
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims abstract description 6
- 229960003438 aspartame Drugs 0.000 claims abstract description 6
- 239000011230 binding agent Substances 0.000 claims abstract description 6
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 6
- 239000000945 filler Substances 0.000 claims abstract description 6
- 239000000080 wetting agent Substances 0.000 claims abstract description 6
- 239000004615 ingredient Substances 0.000 claims abstract description 4
- 239000002994 raw material Substances 0.000 claims description 46
- 240000008397 Ganoderma lucidum Species 0.000 claims description 32
- 235000001637 Ganoderma lucidum Nutrition 0.000 claims description 32
- 239000008187 granular material Substances 0.000 claims description 18
- 238000012856 packing Methods 0.000 claims description 14
- 239000001856 Ethyl cellulose Substances 0.000 claims description 10
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims description 10
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims description 10
- 229920001249 ethyl cellulose Polymers 0.000 claims description 10
- 235000019325 ethyl cellulose Nutrition 0.000 claims description 10
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims description 10
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims description 10
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 10
- 230000001413 cellular effect Effects 0.000 claims description 9
- 238000004140 cleaning Methods 0.000 claims description 9
- 239000012535 impurity Substances 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 239000003814 drug Substances 0.000 claims description 7
- 229910000831 Steel Inorganic materials 0.000 claims description 6
- 238000001035 drying Methods 0.000 claims description 6
- 238000007689 inspection Methods 0.000 claims description 6
- 239000002245 particle Substances 0.000 claims description 6
- 239000010959 steel Substances 0.000 claims description 6
- 230000001954 sterilising effect Effects 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 6
- 235000019359 magnesium stearate Nutrition 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 241001489091 Ganoderma sinense Species 0.000 claims description 3
- 230000003064 anti-oxidating effect Effects 0.000 claims description 3
- 230000008676 import Effects 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
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- 238000005070 sampling Methods 0.000 claims description 3
- 230000002000 scavenging effect Effects 0.000 claims description 3
- 238000007789 sealing Methods 0.000 claims description 3
- 239000003826 tablet Substances 0.000 claims description 3
- 238000005406 washing Methods 0.000 claims description 3
- 239000002351 wastewater Substances 0.000 claims description 3
- -1 hydroxyl propyl Chemical group 0.000 abstract description 4
- 235000016709 nutrition Nutrition 0.000 abstract description 4
- 238000003860 storage Methods 0.000 abstract description 3
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- SERLAGPUMNYUCK-YJOKQAJESA-N 6-O-alpha-D-glucopyranosyl-D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O SERLAGPUMNYUCK-YJOKQAJESA-N 0.000 abstract 2
- 235000006679 Mentha X verticillata Nutrition 0.000 abstract 1
- 235000002899 Mentha suaveolens Nutrition 0.000 abstract 1
- 235000001636 Mentha x rotundifolia Nutrition 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 239000002075 main ingredient Substances 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 description 4
- 238000002372 labelling Methods 0.000 description 3
- 230000007774 longterm Effects 0.000 description 3
- 229920002101 Chitin Polymers 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
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- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000035784 germination Effects 0.000 description 1
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- 230000035800 maturation Effects 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
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Abstract
The invention relates to a buccal tablet prepared from ganoderma broken-down wall spore powder, and belongs to the technical field of medical and health-care foods. The buccal tablet is prepared from the following components by weight percent: 40-60% of a main ingredient ganoderma broken-down wall spore powder, 30-50% of fillers isomaltitol and xylitol (a ratio of isomaltitol to xylitol is 1:1), 1-2% of an aromatic mint oil, 0.5-1.5% of a wetting agent hydroxyl propyl cellulose (HPC), 1.5-2.5% of a binder ethylecellulose (EC), 0.5-1.5% of a disintegrating agent polyvinylpyrrolidone (PVP), 0.5-0.8% of a corrigent Aspartame and a tabletting lubricant: 0.5-1% of a tabletting lubricant. The ganoderma broken-down wall spore powder buccal tablets provided by the invention have the beneficial effects that ganoderma spore powder is convenient to carry and take and is not easy to deteriorate after long storage, the unique taste of the ganoderma spore powder is maintained, and the buccal tablet is convenient for a human body can conveniently uptake nutritional ingredients.
Description
Technical field
The invention belongs to medicine and health food technology field, relate in particular to a kind of Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet.
Background technology
Ganoderma is as the valuable ingredient of Chinese medicine in the Chinese traditional medicine treasure-house, over the past thousands of years by the Chinese medicine practitioner be widely used in curing the disease, in the prescription such as health preserving, life lengthening.Ganoderma spore powder is that Ganoderma sporophore is when growing into the maturation period, eruption very tiny Powdered seed out from Ganoderma sporophore, be used for breeding the next generation, under certain temperature, damp condition, the Ganoderma sporophore of Ganoderma spore powder germination and growth Cheng Xin.The Ganoderma spore powder individual particle is that naked eyes institute is invisible, and the individual particle size only has 6 to 8 microns, is equivalent to a thirtieth of hair diameter.Ganoderma spore powder is equivalent to the pollen of flower, the fruit of fruit tree.Ganoderma spore powder particles outer wrapping the chitin shell of one deck hard, affect absorption of human body, be conducive to absorption of human body after broken chitin shell,, if the Ganoderma spore powder long term exposure is deposited perishablely in air in addition, also can cause human body to be difficult to absorb effective nutritional labeling.
Summary of the invention
According to above deficiency, the purpose of this invention is to provide a kind of Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet, facilitate carrying and taking of Ganoderma spore powder, solve the Ganoderma spore powder long-term storage and guarantee the quality, keep the Ganoderma spore powder unique taste, facilitate the more effective absorption nutritional labeling of human body.
To achieve these goals, the technical solution used in the present invention is: a kind of Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet, Sporoderm-broken Ganoderma Lucidum Spore powder is made buccal tablet, and the raw material mass mixture ratio of described ganoderma lucidium spore powder wall breaking buccal tablet is: 1, major ingredient: Sporoderm-broken Ganoderma Lucidum Spore powder, content 40%-60%; 2, filler: the pure and mild xylitol of dextrinose (both proportioning is 1: 1), content 30%-50%; 3, aromatic: Oleum menthae, content 1%-2%; 4, wetting agent: hydroxypropyl cellulose (HPC), content 0.5%-1.5%; 5, binding agent: ethyl cellulose (EC), content 1.5%-2.5%; 6, disintegrating agent: polyvinylpyrrolidone (PVP), content 0.5%-1.5%; 7, correctives: aspartame, 0.5%-0.8%; 8, tabletting lubricant: magnesium stearate, content 0.5%-1%.
Described ganoderma lucidium spore powder wall breaking buccal tablet fabrication processing is: raw material Ganoderma spore powder quality inspection-cleaning-oven dry-lucidium spore powder wall breaking-oven dry-batching-pelletize-tabletting-sterilizing-packing; Fabrication processing is the quality inspection of (1) raw material Ganoderma spore powder in detail: according to being put down in writing in the Pharmacopoeia of the People's Republic of China: lucidum variety has kind more than 100, what can be used as medicine only has Ganoderma and Ganoderma lucidum (Leyss. Ex Fr.) Karst., and this ganoderma lucidium spore powder wall breaking buccal tablet raw material is chosen Dabie Mountain and originated in red ganoderma or Ganoderma spore powder that Ganoderma sinense Zhao Xu et Zhang produces; Choose the Ganoderma spore powder that produces in then to 2 year, all spore powders all need cold preservation in icebox deposit; The essential free from extraneous odour of Ganoderma spore powder, without rotting to go mouldy, total plate count meets national standard; The spore powder sampling observation, microscopically spore powder full grains, special-shaped granule is less than 5%-10%; In raw material, non-spore powder impurity is less than 1%-5%; (2) clean: after the quality inspection of raw material spore powder is completed, start to clean, use the raw material cleaning robot to clean; Water for cleaning is for purifying waste water, water temperature 20-30 degree centigrade; Scavenging period is 10-20 minute, and follows uniform stirring; After washing is completed, use the microporous filter machine complete raw material and moisture from; Re-use centrifuge and separate residue insoluble in water impurity; (3) oven dry: raw material is dried operation after cleaning and rejecting impurity, uses dehydrator, temperature 50-60 degree centigrade; The stacking even thickness of raw material, higher than the 20-30 millimeter; Drying time is 20-40 minute, turns over once whole in every ten minutes; (4) lucidium spore powder wall breaking: start breaking cellular wall after the Ganoderma spore powder oven dry, select the import pottery to roll rod, roll breaking cellular wall; , for guaranteeing sporoderm-broken rate, once roll raw material weight not higher than 2 kilograms-3 kilograms; The time of rolling is 40-60 minute; (5) oven dry again:, through after long-time breaking cellular wall, before next process is produced, need to again remove the moisture in raw material, bake out temperature 40-60 degree centigrade; The stacking even thickness of raw material, must not be higher than the 20-30 millimeter; Drying time is 5-10 minute; (6) batching: the exosporium-broken spore powder raw material after oven dry mixes according to proportion scale and filler, wetting agent, binding agent, correctives, disintegrating agent uniform stirring, is uniformly mixed time 20-40 minute; (7) pelletize: after batching is completed, cross 10 orders-20 order stainless (steel) wire with oscillating granulator and granulate, oven dry,, with 10 orders-20 order stainless (steel) wire granulate, obtain dried granule; (8) tabletting: feed particles, through the row tabletting, is proportionally called in aromatic, tabletting lubricant, and tablet machine uses the mould bore to be the 8-15 millimeter, and tabletting thickness is the 4-6 millimeter; Diameter 8-15 millimeter, the heavy 200-400 milligram of sheet; (9) sterilizing: after tabletting is completed through ultraviolet radiation 10-30 second; (10) packing: the buccal tablet granule after sterilizing is packed, used the streamline packing; Be packaged as and pack, all indexs are carried out according to the relevant medical rules and regulations of country; For example: a is aluminum-plastic packaged, and packaged configuration is template, and single buccal tablet granule seals separately; B sealing medicinal cupping packing, protection against the tide, anti-oxidation; C does not get rid of design novel package scheme.
The invention has the beneficial effects as follows: facilitate carrying and taking of Ganoderma spore powder, long-term storage is not perishable, keeps the Ganoderma spore powder unique taste, facilitates the more effective absorption nutritional labeling of human body.
The specific embodiment
Further the present invention is illustrated below in conjunction with the specific embodiment;
Embodiment 1: a kind of Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet, Sporoderm-broken Ganoderma Lucidum Spore powder is made buccal tablet, and described ganoderma lucidium spore powder wall breaking buccal tablet raw material mass mixture ratio is: Sporoderm-broken Ganoderma Lucidum Spore powder, 50%; Hydroxyl isomaltulose 22%, xylitol 22%; Oleum menthae 1%; Hydroxypropyl cellulose (HPC), 1%; Ethyl cellulose (EC), 2%; Polyvinylpyrrolidone (PVP), 1%; Aspartame, 0.5%; Magnesium stearate, content 0.5%.Raw material Ganoderma spore powder quality inspection-cleaning-oven dry-lucidium spore powder wall breaking-oven dry-batching-pelletize-tabletting-sterilizing-packing; Idiographic flow is the quality inspection of (1) raw material Ganoderma spore powder: according to being put down in writing in the Pharmacopoeia of the People's Republic of China: lucidum variety has kind more than 100, what can be used as medicine only has Ganoderma and Ganoderma lucidum (Leyss. Ex Fr.) Karst., and this ganoderma lucidium spore powder wall breaking buccal tablet raw material is chosen Dabie Mountain and originated in red ganoderma or Ganoderma spore powder that Ganoderma sinense Zhao Xu et Zhang produces; Choose the Ganoderma spore powder that produces in then to 2 year, all spore powders all need cold preservation in icebox deposit; The essential free from extraneous odour of Ganoderma spore powder, without rotting to go mouldy, total plate count meets national standard; The spore powder sampling observation, microscopically spore powder full grains, special-shaped granule is less than 5%-10%; In raw material, non-spore powder impurity is less than 1%-5%; (2) clean: after the quality inspection of raw material spore powder is completed, start to clean, use the raw material cleaning robot to clean; Water for cleaning is for purifying waste water, water temperature 20-30 degree centigrade; Scavenging period is 10-20 minute, and follows uniform stirring; After washing is completed, use the microporous filter machine complete raw material and moisture from; Re-use centrifuge and separate residue insoluble in water impurity; (3) oven dry: raw material is dried operation after cleaning and rejecting impurity, uses dehydrator, temperature 50-60 degree centigrade; The stacking even thickness of raw material, higher than the 20-30 millimeter; Drying time is 20-40 minute, turns over once whole in every ten minutes; (4) lucidium spore powder wall breaking: start breaking cellular wall after the Ganoderma spore powder oven dry, select the import pottery to roll rod, roll breaking cellular wall; , for guaranteeing sporoderm-broken rate, once roll raw material weight not higher than 2 kilograms-3 kilograms; The time of rolling is 40-60 minute; (5) oven dry again:, through after long-time breaking cellular wall, before next process is produced, need to again remove the moisture in raw material, bake out temperature 40-60 degree centigrade; The stacking even thickness of raw material, must not be higher than the 20-30 millimeter; Drying time is 5-10 minute; (6) batching: the exosporium-broken spore powder raw material after oven dry mixes according to proportion scale and filler, wetting agent, binding agent, correctives, disintegrating agent uniform stirring, is uniformly mixed time 20-40 minute; (7) pelletize: after batching is completed, cross 10 orders-20 order stainless (steel) wire with oscillating granulator and granulate, oven dry,, with 10 orders-20 order stainless (steel) wire granulate, obtain dried granule; (8) tabletting: feed particles, through the row tabletting, is proportionally called in aromatic, tabletting lubricant, and tablet machine uses the mould bore to be the 8-15 millimeter, and tabletting thickness is the 4-6 millimeter; Diameter 8-15 millimeter, the heavy 200-400 milligram of sheet; (9) sterilizing: after tabletting is completed through ultraviolet radiation 10-30 second; (10) packing: the buccal tablet granule after sterilizing is packed, used the streamline packing; Be packaged as and pack, all indexs are carried out according to the relevant medical rules and regulations of country; For example: a is aluminum-plastic packaged, and packaged configuration is template, and single buccal tablet granule seals separately; B sealing medicinal cupping packing, protection against the tide, anti-oxidation; C does not get rid of design novel package scheme.
Embodiment 2: a kind of Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet, Sporoderm-broken Ganoderma Lucidum Spore powder is made buccal tablet, and described ganoderma lucidium spore powder wall breaking buccal tablet raw material mass mixture ratio is: Sporoderm-broken Ganoderma Lucidum Spore powder, 60%; Hydroxyl isomaltulose 17%, xylitol 17%; Oleum menthae 1%; Hydroxypropyl cellulose (HPC), 1%; Ethyl cellulose (EC), 2.5%; Polyvinylpyrrolidone (PVP), 0.5%; Aspartame, 0.5%; Magnesium stearate, content 0.5%.Raw material Ganoderma spore powder quality inspection-cleaning-oven dry-lucidium spore powder wall breaking-oven dry-batching-pelletize-tabletting-sterilizing-packing, concrete processing as described in Example 1.
Embodiment 3: a kind of Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet, Sporoderm-broken Ganoderma Lucidum Spore powder is made buccal tablet, and described ganoderma lucidium spore powder wall breaking buccal tablet raw material mass mixture ratio is: Sporoderm-broken Ganoderma Lucidum Spore powder, 44%; Hydroxyl isomaltulose 25%, xylitol 25%; Oleum menthae 1%; Hydroxypropyl cellulose (HPC), 1%; Ethyl cellulose (EC), 1.5%; Polyvinylpyrrolidone (PVP), 1.5%; Aspartame, 0.5%; Magnesium stearate, content 0.5%.Raw material Ganoderma spore powder quality inspection-cleaning-oven dry-lucidium spore powder wall breaking-oven dry-batching-pelletize-tabletting-sterilizing-packing, concrete processing as described in Example 1.
It should be noted that finally: obviously, above-described embodiment is only for example of the present invention clearly is described, and is not the restriction to embodiment.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description, the apparent variation of being extended out thus or change still are among protection scope of the present invention.
Claims (2)
1. a Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet, make buccal tablet with Sporoderm-broken Ganoderma Lucidum Spore powder, is characterised in that the raw material mass mixture ratio of described ganoderma lucidium spore powder wall breaking buccal tablet is: 1, major ingredient: Sporoderm-broken Ganoderma Lucidum Spore powder, content 40%-60%; 2, filler: the pure and mild xylitol of dextrinose (both proportioning is 1: 1), content 30%-50%; 3, aromatic: Oleum menthae, content 1%-2%; 4, wetting agent: hydroxypropyl cellulose (HPC), content 0.5%-1.5%; 5, binding agent: ethyl cellulose (EC), content 1.5%-2.5%; 6, disintegrating agent: polyvinylpyrrolidone (PVP), content 0.5%-1.5%; 7, correctives: aspartame, 0.5%-0.8%; 8, tabletting lubricant: magnesium stearate, content 0.5%-1%.
2. Sporoderm-broken Ganoderma Lucidum Spore powder buccal tablet as claimed in claim 1, is characterized in that described ganoderma lucidium spore powder wall breaking buccal tablet fabrication processing is: raw material Ganoderma spore powder quality inspection-cleaning-oven dry-lucidium spore powder wall breaking-oven dry-batching-pelletize-tabletting-sterilizing-packing; Fabrication processing is the quality inspection of (1) raw material Ganoderma spore powder in detail: according to being put down in writing in the Pharmacopoeia of the People's Republic of China: lucidum variety has kind more than 100, what can be used as medicine only has Ganoderma and Ganoderma lucidum (Leyss. Ex Fr.) Karst., and this ganoderma lucidium spore powder wall breaking buccal tablet raw material is chosen Dabie Mountain and originated in red ganoderma or Ganoderma spore powder that Ganoderma sinense Zhao Xu et Zhang produces; Choose the Ganoderma spore powder that produces in then to 2 year, all spore powders all need cold preservation in icebox deposit; The essential free from extraneous odour of Ganoderma spore powder, without rotting to go mouldy, total plate count meets national standard; The spore powder sampling observation, microscopically spore powder full grains, special-shaped granule is less than 5%-10%; In raw material, non-spore powder impurity is less than 1%-5%; (2) clean: after the quality inspection of raw material spore powder is completed, start to clean, use the raw material cleaning robot to clean; Water for cleaning is for purifying waste water, water temperature 20-30 degree centigrade; Scavenging period is 10-20 minute, and follows uniform stirring; After washing is completed, use the microporous filter machine complete raw material and moisture from; Re-use centrifuge and separate residue insoluble in water impurity; (3) oven dry: raw material is dried operation after cleaning and rejecting impurity, uses dehydrator, temperature 50-60 degree centigrade; The stacking even thickness of raw material, higher than the 20-30 millimeter; Drying time is 20-40 minute, turns over once whole in every ten minutes; (4) lucidium spore powder wall breaking: start breaking cellular wall after the Ganoderma spore powder oven dry, select the import pottery to roll rod, roll breaking cellular wall; , for guaranteeing sporoderm-broken rate, once roll raw material weight not higher than 2 kilograms-3 kilograms; The time of rolling is 40-60 minute; (5) oven dry again:, through after long-time breaking cellular wall, before next process is produced, need to again remove the moisture in raw material, bake out temperature 40-60 degree centigrade; The stacking even thickness of raw material, must not be higher than the 20-30 millimeter; Drying time is 5-10 minute; (6) batching: the exosporium-broken spore powder raw material after oven dry mixes according to proportion scale and filler, wetting agent, binding agent, correctives, disintegrating agent uniform stirring, is uniformly mixed time 20-40 minute; (7) pelletize: after batching is completed, cross 10 orders-20 order stainless (steel) wire with oscillating granulator and granulate, oven dry,, with 10 orders-20 order stainless (steel) wire granulate, obtain dried granule; (8) tabletting: feed particles, through the row tabletting, is proportionally called in aromatic, tabletting lubricant, and tablet machine uses the mould bore to be the 8-15 millimeter, and tabletting thickness is the 4-6 millimeter; Diameter 8-15 millimeter, the heavy 200-400 milligram of sheet; (9) sterilizing: after tabletting is completed through ultraviolet radiation 10-30 second; (10) packing: the buccal tablet granule after sterilizing is packed, used the streamline packing; Be packaged as and pack, all indexs are carried out according to the relevant medical rules and regulations of country; For example: a is aluminum-plastic packaged, and packaged configuration is template, and single buccal tablet granule seals separately; B sealing medicinal cupping packing, protection against the tide, anti-oxidation; C does not get rid of design novel package scheme.
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| CN103932000A (en) * | 2014-04-30 | 2014-07-23 | 吉林市盛誉美康科技有限公司 | Ganoderma lucidum spore chewable tablet combined with bifidus factor as well as preparation technology thereof |
| CN104323230A (en) * | 2014-11-19 | 2015-02-04 | 清源 | Wall-breaking truffle lozenge and preparation method thereof |
| CN104820073A (en) * | 2015-05-05 | 2015-08-05 | 李朝谦 | Method for quickly and simply detecting impurities of ganoderma lucidum spore powder |
| CN105767999A (en) * | 2016-03-17 | 2016-07-20 | 孙继勇 | Buccal tablet containing wall-broken ganoderma lucidum spore powder, honey and propolis and production method thereof |
| CN106307498A (en) * | 2016-08-23 | 2017-01-11 | 安徽阳光药业有限公司 | Ganoderma lucidum lozenge and preparation method thereof |
| CN106581084A (en) * | 2016-12-15 | 2017-04-26 | 湖南中健欣元生物科技有限公司 | Ganoderma broken-down wall pellet lozenge and preparing method thereof |
| CN108968032A (en) * | 2018-08-23 | 2018-12-11 | 安徽德源堂生物科技有限公司 | A kind of preprocess method of lucidum spore powder |
| CN109480271A (en) * | 2017-09-11 | 2019-03-19 | 孙继勇 | A kind of preparation method of ganoderma spove powder dripping pill |
| CN112021555A (en) * | 2020-08-31 | 2020-12-04 | 山东省农业科学院农产品研究所 | Ganoderma lucidum spore powder tablet and preparation method thereof |
| CN114631598A (en) * | 2022-04-09 | 2022-06-17 | 吉林省爱康寿生物科技有限公司 | Non-waste preparation treatment process for industrialization of cut-log ganoderma lucidum |
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Cited By (14)
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| CN103932000A (en) * | 2014-04-30 | 2014-07-23 | 吉林市盛誉美康科技有限公司 | Ganoderma lucidum spore chewable tablet combined with bifidus factor as well as preparation technology thereof |
| CN103932000B (en) * | 2014-04-30 | 2015-11-18 | 吉林市盛誉美康科技有限公司 | A kind of Reishi sporule powder chewable tablet of compound Oilgosaccharkdes and preparation technology thereof |
| CN104323230A (en) * | 2014-11-19 | 2015-02-04 | 清源 | Wall-breaking truffle lozenge and preparation method thereof |
| CN104323230B (en) * | 2014-11-19 | 2016-03-16 | 清源 | Broken wall ferfas lozenge and preparation method thereof |
| CN104820073A (en) * | 2015-05-05 | 2015-08-05 | 李朝谦 | Method for quickly and simply detecting impurities of ganoderma lucidum spore powder |
| CN105767999A (en) * | 2016-03-17 | 2016-07-20 | 孙继勇 | Buccal tablet containing wall-broken ganoderma lucidum spore powder, honey and propolis and production method thereof |
| CN106307498A (en) * | 2016-08-23 | 2017-01-11 | 安徽阳光药业有限公司 | Ganoderma lucidum lozenge and preparation method thereof |
| CN106581084A (en) * | 2016-12-15 | 2017-04-26 | 湖南中健欣元生物科技有限公司 | Ganoderma broken-down wall pellet lozenge and preparing method thereof |
| CN109480271A (en) * | 2017-09-11 | 2019-03-19 | 孙继勇 | A kind of preparation method of ganoderma spove powder dripping pill |
| CN108968032A (en) * | 2018-08-23 | 2018-12-11 | 安徽德源堂生物科技有限公司 | A kind of preprocess method of lucidum spore powder |
| CN112021555A (en) * | 2020-08-31 | 2020-12-04 | 山东省农业科学院农产品研究所 | Ganoderma lucidum spore powder tablet and preparation method thereof |
| CN114631598A (en) * | 2022-04-09 | 2022-06-17 | 吉林省爱康寿生物科技有限公司 | Non-waste preparation treatment process for industrialization of cut-log ganoderma lucidum |
| CN115068424A (en) * | 2022-07-15 | 2022-09-20 | 中农弘仁纳米生物科技(北京)有限公司 | Preparation method and application of nanoscale wall-broken ganoderma lucidum spore powder |
| CN115068424B (en) * | 2022-07-15 | 2024-05-24 | 中农弘仁纳米生物科技(北京)有限公司 | Preparation method and application of nanoscale wall-broken ganoderma lucidum spore powder |
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