CN103479760A - Disease-resistant and egg-increasing traditional Chinese sustained release tablet for poultry and preparation method thereof - Google Patents
Disease-resistant and egg-increasing traditional Chinese sustained release tablet for poultry and preparation method thereof Download PDFInfo
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- CN103479760A CN103479760A CN201310448787.3A CN201310448787A CN103479760A CN 103479760 A CN103479760 A CN 103479760A CN 201310448787 A CN201310448787 A CN 201310448787A CN 103479760 A CN103479760 A CN 103479760A
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Abstract
The invention relates to a disease-resistant and egg-increasing traditional Chinese sustained release tablet for poultry and a preparation method thereof. According to the traditional Chinese medicine theory and the sustained release preparation theory, scientific medicine compatibility is achieved. The traditional Chinese sustained release tablet comprises the following drug substances: acanthopanax, Chinese angelica, prepared fructus arctii, semen cuscutae, fructus gardeniae, mugwort leaf, hawthorn and shizandra berry. The preparation method comprises the following steps: adding water into raw materials, decocting, filtering and concentrating the filtrate; pouring the concentrated solution into a groove-shaped mixing machine, continually adding microcrystalline cellulose, hydroxypropyl methylcellulose and other filling auxiliary materials, softening the materials, pelletizing and tabletting to obtain the disease-resistant and egg-increasing traditional Chinese sustained release tablet for poultry. The preparation method is good in curative effect and free from medicine residues and toxic and side effects, reduces the administration frequency, has high medicine content, is safe and reliable, and has relatively high social and economic benefits.
Description
Technical field
The present invention relates to a kind of fowl Chinese medicine preparation, particularly relate to a kind of Chinese medicine sustained release tablets for the birds resisting-disease increasing-egg and preparation method thereof.
Background technology
Along with improving constantly of our living standard, Green Product more and more is subject to everybody's welcome.People have had higher pursuit to health and the nutrition of food by value, wherein for the quality of eggs, pursue and become increasingly conspicuous especially.Therefore China is populous, huge to eggs necessary volume demand, develops nuisanceless Carnis Gallus domesticus, the safe egg of green high yield to ensure we healthy, increase economic efficiency most important.
China's cultured birds mainly adopts the mode of plant, for preventing the generation of birds infectious disease, adds for a long time antibiotic in feedstuff, causes drug residue to have a strong impact on our healthy.And adopt this method can reduce the function of laying eggs of chicken fowl, the quality of meat egg reduces greatly.
For solving above, be topic, this research group adopts the natural pure Chinese medicine of safety nuisance free, by slow release, continues medication, and strengthens the immunity of chicken fowl, and defending and fighting against diseases improves egg production, improves the meat Egg Quality, has effect significantly.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, provide a kind of and improve immunity, increase the fowl Chinese medicine sustained release tablets of egg.
Another object of the present invention is to provide the preparation method of above-mentioned slow releasing tablet.
The objective of the invention is to be achieved through the following technical solutions:
A kind of Chinese medicine sustained release tablets for the birds resisting-disease increasing-egg comprises following raw material:
Radix Et Caulis Acanthopanacis Senticosi, Radix Angelicae Sinensis, Fructus Arctii processed, Semen Cuscutae, Fructus Gardeniae, Folium Artemisiae Argyi, Fructus Crataegi, Fructus Schisandrae Chinensis, microcrystalline Cellulose, hypromellose.
1, a kind of Chinese medicine sustained release tablets for the birds resisting-disease increasing-egg and preparation method thereof, it is characterized in that: the crude drug by following row weight portion forms, Radix Et Caulis Acanthopanacis Senticosi 10-20 part, Radix Angelicae Sinensis 2-4 part, Fructus Arctii 5-10 part processed, Semen Cuscutae 5-7 part, Fructus Gardeniae 2-4 part, Folium Artemisiae Argyi 1-2 part, Fructus Crataegi 1-2 part, Fructus Schisandrae Chinensis 5-10 part, microcrystalline Cellulose 10-20 part, hypromellose 20-40 part.
2, the Chinese medicine sustained release tablets for the birds resisting-disease increasing-egg according to claim 1, is characterized in that Radix Et Caulis Acanthopanacis Senticosi 7-8 part, Radix Angelicae Sinensis 4-5 part, Fructus Arctii 7-8 part processed, Semen Cuscutae 2-4 part, Fructus Gardeniae 3-5 part, Folium Artemisiae Argyi 1-2 part, Fructus Crataegi 1-2 part, Fructus Schisandrae Chinensis 7-8 part, microcrystalline Cellulose 5-10 part, hypromellose 10-20 part.
3, the Chinese medicine sustained release tablets for the birds resisting-disease increasing-egg according to claim 1, characterized by further comprising the filling adjuvant, and the weight fraction of interpolation is 10-20 part.
4, the Chinese medicine sustained release tablets for the birds resisting-disease increasing-egg according to claim 1, is characterized in that described filling adjuvant comprises magnesium stearate, carboxymethyl starch sodium.
A kind of preparation method of the Chinese medicine sustained release tablets for the birds resisting-disease increasing-egg is:
(1) above-mentioned raw material is removed to the cutting and grinding of impurity clean dry, be placed in heating tank, add the water of 5 times of volumes, repeat to decoct 3 times, filter and collect filtrate, filtrate filter pressing, concentrated.
(2) pour above-mentioned concentrated solution and microcrystalline Cellulose, hypromellose into trough type mixing machine, soft material processed, granulate dry, adds auxiliary materials and mixing, and tabletting obtains this slow releasing tablet.
The invention has the advantages that:
(1) the present invention adopts natural Chinese medicines Radix Et Caulis Acanthopanacis Senticosi, Radix Angelicae Sinensis, Fructus Arctii processed, Semen Cuscutae, Fructus Gardeniae, Folium Artemisiae Argyi, Fructus Crataegi, the Fructus Schisandrae Chinensis of safety nuisance free, and the compatibility effect is better.The party can effectively improve the chicken immunity of fowl, improves laying rate, improves the meat egg quality.
(2) the present invention adopts decocting method to extract, and does not relate to organic reagent, safety, and environmentally safe, have significant economic results in society.
(3) the present invention adopts slow release medication theory, and Chinese drug preparation is become to slow releasing tablet.Overcoming to have now just has dosage form content low, and administration frequency is high and release is very fast several times, and absorption difference causes the drug wastage waste.
(4) the present invention is according to chicken fowl physiological structure, and by oral administration, medicine can slowly discharge in intestinal, and long-acting playing a role improved bioavailability, saves dosage.
The specific embodiment
Example 1: a kind of Chinese medicine sustained release tablets for the birds resisting-disease increasing-egg, formed Radix Et Caulis Acanthopanacis Senticosi 10-20 part, Radix Angelicae Sinensis 2-4 part, Fructus Arctii 5-10 part processed, Semen Cuscutae 5-7 part, Fructus Gardeniae 2-4 part, Folium Artemisiae Argyi 1-2 part, Fructus Crataegi 1-2 part, Fructus Schisandrae Chinensis 5-10 part by the crude drug by following row weight portion.
Preparation method: (1) removes the cutting and grinding of impurity clean dry by raw material, is placed in heating tank, adds the water of 5 times of volumes, decocts 3 times, filters and collects filtrate, filtrate filter pressing, concentrated.(2) pour above-mentioned concentrated solution and microcrystalline Cellulose 10-20 part, hypromellose 20-40 part into trough type mixing machine, soft material processed, (baking temperature 70-90 ℃ granulates, granule water content after dry≤5%), add 1 part of magnesium stearate, mix, last tabletting obtains this slow releasing tablet.
Example 2: a kind of Chinese medicine sustained release tablets for the birds resisting-disease increasing-egg, formed Radix Et Caulis Acanthopanacis Senticosi 7-8 part, Radix Angelicae Sinensis 4-5 part, Fructus Arctii 7-8 part processed, Semen Cuscutae 2-4 part, Fructus Gardeniae 3-5 part, Folium Artemisiae Argyi 1-2 part, Fructus Crataegi 1-2 part, Fructus Schisandrae Chinensis 7-8 part by the crude drug by following row weight portion.
Preparation method: (1) removes the cutting and grinding of impurity clean dry by raw material, is placed in heating tank, adds the water of 5 times of volumes, decocts 3 times, filters and collects filtrate, filtrate filter pressing, concentrated.(2) pour above-mentioned concentrated solution and microcrystalline Cellulose 5-10 part, hypromellose 10-20 part into trough type mixing machine, soft material processed, (baking temperature 70-90 ℃ granulates, granule water content after dry≤5%), add 1 part of carboxymethyl starch sodium, mix, last tabletting obtains this slow releasing tablet.
Example 3: zoopery
Adopt the Chinese medicine sustained release tablets of fowl of the present invention with resisting-disease increasing-egg, chicken is tried out.
Choose at random 300 of the laying hens that certain raises factory, 18-20 age in week.Laying hen is divided into to three groups at random, and wherein one group is the blank group, normal diet.Test 1 group and regularly take the made slow release tablet of example 1, once a day, an a slice.Test 2 groups and regularly take the made slow release tablet of example 2, once a day, an a slice.Below take continuously 2 months.
Statistical result (in Table 1):
Table 1, each group experimental result statistical table
Experimental result shows, fowl of the present invention increases by 30% left and right with the Chinese medicine sustained release tablets of resisting-disease increasing-egg, single egg size amount 10% left and right, and in egg, cholesterol reduces by 40% left and right, has significant application prospect and potentiality.
The purposes that should be appreciated that these embodiment only limits the scope of the invention for the present invention being described but not being intended to.In addition; also should understand; after having read technology contents of the present invention, those skilled in the art can make various changes, modification and/or modification to the present invention, within these all equivalent form of values fall within the protection domain that the application's appended claims limits equally.
Claims (6)
1. Chinese medicine sustained release tablets for the birds resisting-disease increasing-egg and preparation method thereof, it is characterized in that: the crude drug by following row weight portion forms, Radix Et Caulis Acanthopanacis Senticosi 10-20 part, Radix Angelicae Sinensis 2-4 part, Fructus Arctii 5-10 part processed, Semen Cuscutae 5-7 part, Fructus Gardeniae 2-4 part, Folium Artemisiae Argyi 1-2 part, Fructus Crataegi 1-2 part, Fructus Schisandrae Chinensis 5-10 part, microcrystalline Cellulose 10-20 part, hypromellose 20-40 part.
2. the Chinese medicine sustained release tablets for the birds resisting-disease increasing-egg according to claim 1, is characterized in that Radix Et Caulis Acanthopanacis Senticosi 7-8 part, Radix Angelicae Sinensis 4-5 part, Fructus Arctii 7-8 part processed, Semen Cuscutae 2-4 part, Fructus Gardeniae 3-5 part, Folium Artemisiae Argyi 1-2 part, Fructus Crataegi 1-2 part, Fructus Schisandrae Chinensis 7-8 part, microcrystalline Cellulose 5-10 part, hypromellose 10-20 part.
3. the Chinese medicine sustained release tablets for the birds resisting-disease increasing-egg according to claim 1, characterized by further comprising the filling adjuvant, and the weight fraction of interpolation is 10-20 part.
4. the Chinese medicine sustained release tablets for the birds resisting-disease increasing-egg according to claim 1, is characterized in that described filling adjuvant comprises magnesium stearate, carboxymethyl starch sodium.
5. the piece preparation method of the traditional Chinese medicine slow-releasing for the birds resisting-disease increasing-egg according to claim 1, it is characterized in that the method comprises the following steps: (1) removes the cutting and grinding of impurity clean dry by raw material, be placed in heating tank, the water that adds 5 times of volumes, decoct 3 times, filter and collect filtrate, filtrate filter pressing, concentrated; (2) pour above-mentioned concentrated solution and microcrystalline Cellulose, hypromellose into trough type mixing machine, soft material processed, granulate dry, adds adjuvant, and tabletting obtains this slow releasing tablet.
6. the piece preparation method of the traditional Chinese medicine slow-releasing for the birds resisting-disease increasing-egg according to claim 5, it is characterized in that: described granulation baking temperature is 70-90 ℃, dry after granule water content≤5%.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310448787.3A CN103479760A (en) | 2013-09-28 | 2013-09-28 | Disease-resistant and egg-increasing traditional Chinese sustained release tablet for poultry and preparation method thereof |
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| CN201310448787.3A CN103479760A (en) | 2013-09-28 | 2013-09-28 | Disease-resistant and egg-increasing traditional Chinese sustained release tablet for poultry and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20180101772A (en) * | 2017-03-06 | 2018-09-14 | 상하이 지슈아이 바이오 테크놀로지 컴퍼니 리미티드 | Cat feed containing nano microcrystalline cellulose |
-
2013
- 2013-09-28 CN CN201310448787.3A patent/CN103479760A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20180101772A (en) * | 2017-03-06 | 2018-09-14 | 상하이 지슈아이 바이오 테크놀로지 컴퍼니 리미티드 | Cat feed containing nano microcrystalline cellulose |
| KR102374741B1 (en) | 2017-03-06 | 2022-03-14 | 상하이 지슈아이 바이오 테크놀로지 컴퍼니 리미티드 | Cat feed containing nano microcrystalline cellulose |
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Application publication date: 20140101 |