CN103371164B - A kind of Pesticidal combination of fluorine-containing louse sulfanilamide - Google Patents
A kind of Pesticidal combination of fluorine-containing louse sulfanilamide Download PDFInfo
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- CN103371164B CN103371164B CN201210116351.XA CN201210116351A CN103371164B CN 103371164 B CN103371164 B CN 103371164B CN 201210116351 A CN201210116351 A CN 201210116351A CN 103371164 B CN103371164 B CN 103371164B
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- Prior art keywords
- fluorine
- louse
- sulfanilamide
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- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 title claims abstract description 111
- 239000011737 fluorine Substances 0.000 title claims abstract description 111
- 229910052731 fluorine Inorganic materials 0.000 title claims abstract description 111
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 title claims abstract description 101
- 229940124530 sulfonamide Drugs 0.000 title claims abstract description 101
- 230000000361 pesticidal effect Effects 0.000 title claims abstract description 13
- 241000238631 Hexapoda Species 0.000 claims abstract description 82
- 239000000203 mixture Substances 0.000 claims abstract description 57
- 239000005934 Sulfoxaflor Substances 0.000 claims abstract description 56
- ZVQOOHYFBIDMTQ-UHFFFAOYSA-N [methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-lambda(6)-sulfanylidene]cyanamide Chemical compound N#CN=S(C)(=O)C(C)C1=CC=C(C(F)(F)F)N=C1 ZVQOOHYFBIDMTQ-UHFFFAOYSA-N 0.000 claims abstract description 54
- 241000607479 Yersinia pestis Species 0.000 claims abstract description 8
- 239000000375 suspending agent Substances 0.000 claims description 52
- 239000004562 water dispersible granule Substances 0.000 claims description 24
- 239000003795 chemical substances by application Substances 0.000 claims description 23
- 239000003094 microcapsule Substances 0.000 claims description 15
- 241000500437 Plutella xylostella Species 0.000 claims description 13
- 241001414989 Thysanoptera Species 0.000 claims description 12
- 239000000839 emulsion Substances 0.000 claims description 12
- 241000426497 Chilo suppressalis Species 0.000 claims description 11
- 241000008892 Cnaphalocrocis patnalis Species 0.000 claims description 11
- 241000738498 Epitrix pubescens Species 0.000 claims description 10
- 241000256247 Spodoptera exigua Species 0.000 claims description 10
- 241001498622 Cixius wagneri Species 0.000 claims description 9
- 241000255967 Helicoverpa zea Species 0.000 claims description 9
- 241001232130 Maruca testulalis Species 0.000 claims description 9
- 241001249129 Scirpophaga incertulas Species 0.000 claims description 9
- 241000985245 Spodoptera litura Species 0.000 claims description 9
- 239000002304 perfume Substances 0.000 claims description 9
- 239000000725 suspension Substances 0.000 claims description 9
- 241001198505 Anarsia lineatella Species 0.000 claims description 8
- 241001124076 Aphididae Species 0.000 claims description 8
- 241000907661 Pieris rapae Species 0.000 claims description 8
- 241000409991 Mythimna separata Species 0.000 claims description 7
- 239000004563 wettable powder Substances 0.000 claims description 6
- 239000004530 micro-emulsion Substances 0.000 claims description 4
- 150000001408 amides Chemical class 0.000 abstract description 64
- 239000005900 Flonicamid Substances 0.000 abstract description 58
- YBOFEONRFJMHND-UHFFFAOYSA-N [Br].N#CC#N Chemical compound [Br].N#CC#N YBOFEONRFJMHND-UHFFFAOYSA-N 0.000 abstract description 58
- RLQJEEJISHYWON-UHFFFAOYSA-N flonicamid Chemical compound FC(F)(F)C1=CC=NC=C1C(=O)NCC#N RLQJEEJISHYWON-UHFFFAOYSA-N 0.000 abstract description 57
- WPALTCMYPARVNV-UHFFFAOYSA-N tolfenpyrad Chemical compound CCC1=NN(C)C(C(=O)NCC=2C=CC(OC=3C=CC(C)=CC=3)=CC=2)=C1Cl WPALTCMYPARVNV-UHFFFAOYSA-N 0.000 abstract description 57
- FTQWRYSLUYAIRQ-UHFFFAOYSA-N n-[(octadecanoylamino)methyl]octadecanamide Chemical compound CCCCCCCCCCCCCCCCCC(=O)NCNC(=O)CCCCCCCCCCCCCCCCC FTQWRYSLUYAIRQ-UHFFFAOYSA-N 0.000 abstract description 56
- 239000005899 Fipronil Substances 0.000 abstract description 55
- 229940013764 fipronil Drugs 0.000 abstract description 55
- ZOCSXAVNDGMNBV-UHFFFAOYSA-N 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile Chemical compound NC1=C(S(=O)C(F)(F)F)C(C#N)=NN1C1=C(Cl)C=C(C(F)(F)F)C=C1Cl ZOCSXAVNDGMNBV-UHFFFAOYSA-N 0.000 abstract description 54
- PSOVNZZNOMJUBI-UHFFFAOYSA-N chlorantraniliprole Chemical compound CNC(=O)C1=CC(Cl)=CC(C)=C1NC(=O)C1=CC(Br)=NN1C1=NC=CC=C1Cl PSOVNZZNOMJUBI-UHFFFAOYSA-N 0.000 abstract description 45
- 230000000694 effects Effects 0.000 abstract description 19
- 239000000575 pesticide Substances 0.000 abstract description 19
- 150000001875 compounds Chemical class 0.000 abstract description 5
- 235000013339 cereals Nutrition 0.000 abstract description 3
- 235000013399 edible fruits Nutrition 0.000 abstract description 3
- 239000000835 fiber Substances 0.000 abstract description 3
- 230000000749 insecticidal effect Effects 0.000 abstract description 3
- 238000001228 spectrum Methods 0.000 abstract description 3
- 235000013311 vegetables Nutrition 0.000 abstract description 3
- 206010059866 Drug resistance Diseases 0.000 abstract description 2
- 230000007613 environmental effect Effects 0.000 abstract description 2
- 244000144977 poultry Species 0.000 abstract description 2
- 238000003912 environmental pollution Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 57
- 238000012360 testing method Methods 0.000 description 35
- 239000004615 ingredient Substances 0.000 description 21
- 230000003449 preventive effect Effects 0.000 description 21
- 238000013329 compounding Methods 0.000 description 18
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 14
- 240000007594 Oryza sativa Species 0.000 description 14
- 235000007164 Oryza sativa Nutrition 0.000 description 14
- 229910052801 chlorine Inorganic materials 0.000 description 14
- 239000000460 chlorine Substances 0.000 description 14
- 150000001412 amines Chemical class 0.000 description 12
- 238000002360 preparation method Methods 0.000 description 12
- 231100000820 toxicity test Toxicity 0.000 description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 12
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 description 11
- 230000002045 lasting effect Effects 0.000 description 11
- 239000013530 defoamer Substances 0.000 description 10
- 239000002270 dispersing agent Substances 0.000 description 10
- 230000002265 prevention Effects 0.000 description 10
- 230000010165 autogamy Effects 0.000 description 9
- 239000006071 cream Substances 0.000 description 9
- 239000003995 emulsifying agent Substances 0.000 description 9
- 235000009566 rice Nutrition 0.000 description 9
- -1 sulfoxaflor compound Chemical class 0.000 description 9
- 239000008346 aqueous phase Substances 0.000 description 8
- 239000000470 constituent Substances 0.000 description 8
- 238000009472 formulation Methods 0.000 description 8
- 239000002917 insecticide Substances 0.000 description 8
- 239000012071 phase Substances 0.000 description 8
- 241001439019 Phthorimaea operculella Species 0.000 description 7
- 229940079593 drug Drugs 0.000 description 7
- 239000000126 substance Substances 0.000 description 7
- 239000002562 thickening agent Substances 0.000 description 7
- 239000000080 wetting agent Substances 0.000 description 7
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 6
- 230000002528 anti-freeze Effects 0.000 description 6
- 238000013401 experimental design Methods 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 239000004094 surface-active agent Substances 0.000 description 6
- 241000273311 Aphis spiraecola Species 0.000 description 5
- 235000010149 Brassica rapa subsp chinensis Nutrition 0.000 description 5
- 235000000536 Brassica rapa subsp pekinensis Nutrition 0.000 description 5
- 241000499436 Brassica rapa subsp. pekinensis Species 0.000 description 5
- 206010011732 Cyst Diseases 0.000 description 5
- BAOWVDHYZBLYMB-UHFFFAOYSA-N [F].C1=CC=NC=C1 Chemical compound [F].C1=CC=NC=C1 BAOWVDHYZBLYMB-UHFFFAOYSA-N 0.000 description 5
- 208000031513 cyst Diseases 0.000 description 5
- 239000008367 deionised water Substances 0.000 description 5
- 229910021641 deionized water Inorganic materials 0.000 description 5
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 229920002521 macromolecule Polymers 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 239000002574 poison Substances 0.000 description 5
- 231100000614 poison Toxicity 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 239000002904 solvent Substances 0.000 description 5
- 239000003513 alkali Substances 0.000 description 4
- 239000000945 filler Substances 0.000 description 4
- 150000002825 nitriles Chemical class 0.000 description 4
- 239000003960 organic solvent Substances 0.000 description 4
- 229920000742 Cotton Polymers 0.000 description 3
- 239000013543 active substance Substances 0.000 description 3
- 238000013019 agitation Methods 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 3
- 239000006185 dispersion Substances 0.000 description 3
- 230000008595 infiltration Effects 0.000 description 3
- 238000001764 infiltration Methods 0.000 description 3
- 239000003002 pH adjusting agent Substances 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 102000005962 receptors Human genes 0.000 description 3
- 108020003175 receptors Proteins 0.000 description 3
- 239000003381 stabilizer Substances 0.000 description 3
- 230000001988 toxicity Effects 0.000 description 3
- 231100000419 toxicity Toxicity 0.000 description 3
- 230000001018 virulence Effects 0.000 description 3
- KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 description 2
- 235000005637 Brassica campestris Nutrition 0.000 description 2
- 241001301148 Brassica rapa subsp. oleifera Species 0.000 description 2
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 2
- 239000005886 Chlorantraniliprole Substances 0.000 description 2
- 241000207199 Citrus Species 0.000 description 2
- 241000098277 Cnaphalocrocis Species 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 241000255777 Lepidoptera Species 0.000 description 2
- 241000124008 Mammalia Species 0.000 description 2
- 241000233855 Orchidaceae Species 0.000 description 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 2
- 230000008485 antagonism Effects 0.000 description 2
- 238000000498 ball milling Methods 0.000 description 2
- 229910001424 calcium ion Inorganic materials 0.000 description 2
- 235000020971 citrus fruits Nutrition 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 230000003151 ovacidal effect Effects 0.000 description 2
- JMANVNJQNLATNU-UHFFFAOYSA-N oxalonitrile Chemical compound N#CC#N JMANVNJQNLATNU-UHFFFAOYSA-N 0.000 description 2
- 244000045947 parasite Species 0.000 description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 210000004894 snout Anatomy 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 102000009660 Cholinergic Receptors Human genes 0.000 description 1
- 108010009685 Cholinergic Receptors Proteins 0.000 description 1
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 description 1
- 239000005889 Cyantraniliprole Substances 0.000 description 1
- 241000283073 Equus caballus Species 0.000 description 1
- QQKGNOCPSSMOBE-UHFFFAOYSA-N FC(C1=CC=C(C=N1)C(C)C[O])(F)F Chemical compound FC(C1=CC=C(C=N1)C(C)C[O])(F)F QQKGNOCPSSMOBE-UHFFFAOYSA-N 0.000 description 1
- 239000005901 Flubendiamide Substances 0.000 description 1
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 description 1
- 241000258937 Hemiptera Species 0.000 description 1
- 238000012695 Interfacial polymerization Methods 0.000 description 1
- 241000256259 Noctuidae Species 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 241000125167 Rhopalosiphum padi Species 0.000 description 1
- 229930001406 Ryanodine Natural products 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 239000005864 Sulphur Substances 0.000 description 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000000895 acaricidal effect Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000012271 agricultural production Methods 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000012752 auxiliary agent Substances 0.000 description 1
- 150000003851 azoles Chemical class 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000007957 coemulsifier Substances 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- DVBUIBGJRQBEDP-UHFFFAOYSA-N cyantraniliprole Chemical compound CNC(=O)C1=CC(C#N)=CC(C)=C1NC(=O)C1=CC(Br)=NN1C1=NC=CC=C1Cl DVBUIBGJRQBEDP-UHFFFAOYSA-N 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 238000007667 floating Methods 0.000 description 1
- ZGNITFSDLCMLGI-UHFFFAOYSA-N flubendiamide Chemical compound CC1=CC(C(F)(C(F)(F)F)C(F)(F)F)=CC=C1NC(=O)C1=CC=CC(I)=C1C(=O)NC(C)(C)CS(C)(=O)=O ZGNITFSDLCMLGI-UHFFFAOYSA-N 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 230000031852 maintenance of location in cell Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000010413 mother solution Substances 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 231100000194 ovacidal Toxicity 0.000 description 1
- 230000017448 oviposition Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 238000005453 pelletization Methods 0.000 description 1
- 230000026731 phosphorylation Effects 0.000 description 1
- 238000006366 phosphorylation reaction Methods 0.000 description 1
- NAYYNDKKHOIIOD-UHFFFAOYSA-N phthalamide Chemical compound NC(=O)C1=CC=CC=C1C(N)=O NAYYNDKKHOIIOD-UHFFFAOYSA-N 0.000 description 1
- 238000006068 polycondensation reaction Methods 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- JJSYXNQGLHBRRK-SFEDZAPPSA-N ryanodine Chemical compound O([C@@H]1[C@]([C@@]2([C@]3(O)[C@]45O[C@@]2(O)C[C@]([C@]4(CC[C@H](C)[C@H]5O)O)(C)[C@@]31O)C)(O)C(C)C)C(=O)C1=CC=CN1 JJSYXNQGLHBRRK-SFEDZAPPSA-N 0.000 description 1
- 102000042094 ryanodine receptor (TC 1.A.3.1) family Human genes 0.000 description 1
- 108091052345 ryanodine receptor (TC 1.A.3.1) family Proteins 0.000 description 1
- 210000002460 smooth muscle Anatomy 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N41/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
- A01N41/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom containing a sulfur-to-oxygen double bond
- A01N41/04—Sulfonic acids; Derivatives thereof
- A01N41/06—Sulfonic acid amides
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N41/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
- A01N41/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom containing a sulfur-to-oxygen double bond
- A01N41/10—Sulfones; Sulfoxides
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses the Pesticidal combination of a kind of fluorine-containing louse sulfanilamide, containing active components A and the Pesticidal combination of active component B, active components A is selected from fluorine louse sulfanilamide, active component B is selected from any one compound following: flonicamid, bromine cyanogen insect amide, Rynaxypyr, fipronil bisamide, Tolfenpyrad, sulfoxaflor, and the weight ratio of active components A, active component B is 1: 70～70: 1.The present composition can prevent and treat various pests, and has obvious potentiation, expands insecticidal spectrum, and the various pests on vegetable, fruit tree, cereal crops, fibre crops is all had greater activity；And decrease pesticide usage amount, reduce pesticide residual quantity on crop, alleviate environmental pollution；To person poultry safety, Environmental compatibility is good, and insect is not likely to produce Drug resistance.
Description
Technical field
The invention belongs to technical field of pesticide, relate to the Pesticidal combination of a kind of fluorine-containing louse sulfanilamide.
Background technology
Flonicamid (flonicamid) chemical name: N-cyanogen methyl-4-(trifluoromethyl) nicotiamide, molecular formula:
C9H6F3N3O, flonicamid is effective to various suckings pest, and has good osmosis.It can from root to
Stem, the infiltration of leaf portion, but relatively weak to stem, root osmosis by leaf portion.This medicament is by obstruction insect act of sucking
Cause effect.Insect is taken in and quickly stops after medicament sucking, last hungry and dead.
Bromine cyanogen insect amide (Cyantraniliprole), molecular formula: C19H14BrClN6O2, bromine cyanogen insect amide is E.I.Du Pont Company
The second filial generation ryanodine receptor inhibitor insecticides that success is developed after chlorantraniliprole, cyanogen insect amide is by changing phenyl ring
On various polar groups form, have more efficient, applicable crops is more extensive, can effectively prevent and treat Lepidoptera, Semiptera and elytrum
Mesh insect.
The bromo-N-of Rynaxypyr (chlorantraniliprole) chemical name: 3-[4-chloro-2-methyl-6-[(first
Carbamoyl) benzene]-1-(3-chloropyridine-2-base)-1-hydrogen-pyridine-5-Methanamide, molecular formula: C18H14N5O2BrCl2, chlorine worm
Benzoylamide belongs to O-formammidotiazol-benzamide insecticide.Mainly activate blue Buddhist nun's alkali receptor, release smooth muscle and striped muscle
The calcium ion of intracellular storage, causes muscle regulation weak, paralysis, until last insect is dead.It is right that this effective ingredient shows
Mammal and insect orchid Buddhist nun's alkali receptor extremely significantly selective difference, substantially increases mammal and other vertebratess
Safety.
The iodo-N ' of fipronil bisamide (flubendiamide) chemical name: 3--(2-mesyl-1,1-dimethyl ethane
Base-N-{4-[1,2,2,2-tetra-fluoro-1-(trifluoromethyl) ethyl]-O-tolyl } phthalamide, molecular formula:
C23H22F7IN2O4S, fipronil bisamide belongs to Novel ortho benzenedicarboxamide insecticides, activates blue Buddhist nun's alkali recipient cell Intracellular calcium release
Passage, causes the runaway release storing calcium ion.It is the most few in number to act on insect cell orchid Buddhist nun's alkali
(Ryanodine) compound of receptor.Lepidoptera pest is had spectrum preventive effect, produces with existing insecticide no interactions resistance, non-
Often it is suitable for the preventing and treating that existing insecticide produces the insect of resistance.Larva is had very prominent preventive effect, limited to adult preventive effect,
There is no ovicidal action.Slightly conducted by xylem after in infiltration plant body.Resistance of rainwater washing against.
Tolfenpyrad (tolfenpyrad) chemical name: 4-chloro-3-ethyl-1-methyl-N-[4-(p-tolyl epoxide)
Phenyl] pyrazoles-5-amide, molecular formula: C21H22ClN3O2, (its pesticide part is existing in Tolfenpyrad Shi Yuan Mitsubishi chemical company
Belong to pesticide company of Japan) the novel pyrazole heterocyclic insecticidal/acaricidal agent developed, its main mechanism is to stop the oxygen of insecticide
Change phosphorylation, also there is ovicidal, press down food, oviposition deterrence and bactericidal action.
Sulfoxaflor, English common name (sulfoxaflor), molecular formula: C10H10F3N3OS chemical name: [1-[6-
(trifluoromethyl) pyridin-3-yl] ethyl] methyl (oxygen)-λ 4-sulfydryl cyanamide.Sulfoxaflor is a parasite killing of sulfimide
Agent, sulfimide acts on the nervous system of insecticide, i.e. acts on binding site unique in cholinoceptor and plays parasite killing merit
Energy.Can enter in plant through leaf, stem, root absorption.
But, in the real process of agricultural production, pest control is easiest to generate the problem that the product of pest resistance to insecticide
Raw.Different cultivars composition compounds, and is to prevent and treat the method that resistant insect is the most common.Heterogeneity compounds, according to reality
Application effect, judge certain compounding be potentiation, add and, antagonism.In most cases, the compounding effect of pesticide is all
Additive effect, really have potentiation compounding seldom, especially potentiation clearly, co-toxicity coefficient the highest compounding just
Less.Study through inventor, find fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, Rynaxypyr, fluorine worm
Good potentiation can be produced after bisamide, Tolfenpyrad, sulfoxaflor are compounding, and about fluorine louse sulfanilamide and fluorine pyridine worm
The relevant report that amide, bromine cyanogen insect amide, Rynaxypyr, fipronil bisamide, Tolfenpyrad, sulfoxaflor compound is not yet
Open.
Summary of the invention
Resistance that single dose life-time service may bring occurs, degradation problem under drug effect, the Pesticidal combination that the present invention proposes
Containing active components A and active component B, and appropriate surfactant and carrier.
A kind of Pesticidal combination of fluorine-containing louse sulfanilamide, it is characterised in that: containing active components A and active component B, activity becomes
The weight ratio dividing A and active component B is 1: 70～70: 1, and described active components A is selected from fluorine louse sulfanilamide, and active component B is selected from
One in flonicamid, bromine cyanogen insect amide, Rynaxypyr, fipronil bisamide, Tolfenpyrad, sulfoxaflor, lives
Property composition A and active component B weight ratio be preferably 1: 50～30: 1, the weight ratio of fluorine louse sulfanilamide and flonicamid is more preferably
It is 10: 1～1: 20；Fluorine louse sulfanilamide is more preferably 10: 1～1: 20 with the weight ratio of bromine cyanogen insect amide；Fluorine louse sulfanilamide and chlorine worm benzene
The weight ratio of Methanamide is more preferably 10: 1～1: 10；The weight ratio of fluorine louse sulfanilamide and fipronil bisamide is more preferably 10: 1～1:
20；Fluorine louse sulfanilamide is more preferably 10: 1～1: 30 with the weight ratio of Tolfenpyrad；Fluorine louse sulfanilamide and the weight ratio of sulfoxaflor
More preferably 10: 1～1: 30.
The Pesticidal combination of described fluorine-containing louse sulfanilamide is for preventing and treating the purposes of crop pest, and described crops include vegetables
The purposes of insect on dish, fruit tree, cereal crops, fibre crops.
Described purposes, it is characterised in that described insect includes: fleahopper, mythimna separata, bollworm, phthorimaea operculella, sweet
Dish noctuid, diamondback moth, small heart-eating peach worm, applied perfume, striped rice borer, yellow rice borer, rice leaf roller, Pieris rapae, bean-pod borer, rice
Plant hopper, aphid, flea beetle, thrips, aleyrodid, Prodenia litura.
Active components A is 1: 70～70: 1 with the weight ratio of active component B.The generally weight hundred of active component in compositions
Dividing content is the 1%～90% of gross weight, is preferably 5%～85%.According to different preparation types, active component content model
Enclose different.Generally, liquid preparation contains the active substance of by weight 1%～70%, preferably 5%～50%；Gu
Body preparation contains the active substance of by weight 5%～85%, preferably 10%～70%.
At least containing a kind of surfactant in the Pesticidal combination of the present invention, when being beneficial to use, active component is in water
Dispersion.Surface-active contents is the 5%～40% of total formulation weight amount, and surplus is solid or liquid diluent.
The compositions of the present invention through dilution or directly can be used before use by user.Its preparation can be by common
Prepared by the processing method well known to skilled person, after active substance mixes with liquid flux or solid carrier, then will add
Enter one or more in surfactant such as dispersant, stabilizer, wetting agent, emulsifying agent, binding agent, defoamer etc..
The Pesticidal combination of the present invention, can be processed into acceptable dosage form on any pesticide on demand, the most excellent relatively selects
Dosage form is: wettable powder, suspending agent, suspension emulsion, water dispersible granules, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension
Agent-suspending agent.
Compositions comprises following constituent content when making wettable powder: active components A 1%～70%, active component
B1%～70%, dispersant 1.5%～10%, wetting agent 1%～10%, filler surplus.
Compositions includes following constituent content when making water dispersible granules: active components A 1%～70%, active component
B1%～70%, dispersant 1%～12%, wetting agent 1%～8%, disintegrating agent 1%～10%, binding agent 0%～8%, filler
Surplus.
Compositions includes following constituent content when making suspending agent: active components A 1%～50%, active component B1%～
50%, dispersant 1%～10%, wetting agent 1%～10%, defoamer 0.1%～1%, thickening agent 0.01%～2%, freeze proof
Agent 0%～8%, deionized water add to 100%.
Compositions includes following constituent content when making suspension emulsion: active components A 1%～50%, active component B1%～
50%, solvent 0～15%, emulsifying agent 2%～12%, dispersant 2%～10%, defoamer 0.1%～2%, thickening agent
0.01%～2%, antifreeze 0%～8%, stabilizer 0%～3%, water add to 100%.
Compositions comprises following constituent content when making aqueous emulsion: active components A 1%～50%, active component B1%～
50%, solvent 1%～30%, emulsifying agent 1%～20%, co-emulsifier 1%～8%, antifreeze 0%～8%, thickening agent
0.05%～2%, defoamer 0%～2%, deionized water supply surplus.
Compositions comprises following constituent content when making microemulsion: active components A 1%～50%, active component B1%～
50%, solvent 1%～30%, emulsifying agent 5%～20%, antifreeze 0%～8%, thickening agent 0.01%～2%, defoamer
0.01%～2%, stabilizer 0%～4%, deionized water supplies surplus.
Compositions includes following constituent content when making microcapsule suspending agent: active components A 1%～50%, active component
B1%～50%, macromolecule cyst material 3%～10%, dispersant 2%～10%, organic solvent 0%～10%, emulsifying agent
2%～7%, pH adjusting agent 0.1%～5%, deionized water adds to 100%.
Compositions includes following constituent content when making microcapsule suspension-suspendinagent agent: active components A 1%～40%, activity become
Divide B1%～60%, macromolecule cyst material 2%～12%, surfactant 3%～15%, organic solvent 1%～5%, breast
Agent 1%～6%, defoamer 0.01%～5%, thickening agent 0.05%～1%, pH adjusting agent 0.01%～5%, water add to
100%.
The wettable powder the key technical indexes of the present invention:
The water dispersible granules the key technical indexes of the present invention:
The suspending agent the key technical indexes of the present invention:
The suspension emulsion the key technical indexes of the present invention:
The aqueous emulsion the key technical indexes of the present invention:
The microemulsion the key technical indexes of the present invention:
The microcapsule suspending agent the key technical indexes of the present invention:
The microcapsule suspension-suspendinagent agent the key technical indexes of the present invention:
It is an advantage of the current invention that:
(1) fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, Rynaxypyr, fipronil bisamide, Tolfenpyrad,
After sulfoxaflor is compounding, there is notable synergistic and lasting effect；
(2) insecticidal spectrum is expanded, to the fleahopper on vegetable, fruit tree, cereal crops, fibre crops, mythimna separata, bollworm, horse
Bell potato tuber moth, beet armyworm, diamondback moth, small heart-eating peach worm, applied perfume, striped rice borer, yellow rice borer, rice leaf roller, dish
Kattapillar, bean-pod borer, planthopper, aphid, flea beetle, thrips, aleyrodid, Prodenia litura etc. all have greater activity；(3) pesticide is decreased
Dosage, reduces pesticide residual quantity on crop；(4) to person poultry safety, Environmental compatibility is good, and insect is not likely to produce drug resistance
Property.
Detailed description of the invention
Below in conjunction with embodiment, further instruction of the present invention, the percentage ratio in embodiment are all weight percentage, but
The invention is not limited in this.
Application Example one
Embodiment 1～18 wettable powder
By fluorine louse sulfanilamide, effective ingredient B, dispersant, wetting agent, filler mix homogeneously in mixed cylinder, through comminution by gas stream
Machine remixes uniformly after pulverizing, and i.e. can be made into fluorine louse sulfanilamide effective ingredient B wettable powder product, and effective ingredient B includes fluorine
Pyridine insect amide, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, sulfoxaflor one therein.
Concrete formula is shown in Table 1.
Table 1 embodiment 1～18 each component and weight portion
By flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, flonicamid in table
Nitrile exchanges, and can prepare novel formulation.
Table 2 fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad,
Sulfoxaflor and mixture thereof prevent and treat the rice hoppers test of pesticide effectiveness
| Treatment agent | Preparation dosage | 3 days preventive effects (%) after medicine | 14 days preventive effects (%) after medicine |
| Embodiment 1 | 4 grams/acre | 99.43 | 98.25 |
| Embodiment 2 | 3 grams/acre | 98.75 | 99.17 |
| Embodiment 5 | 10 grams/acre | 98.59 | 99.02 |
| Embodiment 6 | 6 grams/acre | 99.35 | 98.86 |
| Embodiment 9 | 11 grams/acre | 99.16 | 98.54 |
| Embodiment 10 | 5 grams/acre | 99.24 | 98.87 |
| Embodiment 13 | 3 grams/acre | 99.08 | 99.49 |
| Embodiment 15 | 7 grams/acre | 98.87 | 98.95 |
| Embodiment 17 | 6 grams/acre | 99.31 | 98.72 |
| 5% fluorine louse sulfanilamide suspending agent (autogamy) | 15 grams/acre | 67.59 | 70.23 |
| 10% flonicamid water dispersible granules | 40 grams/acre | 65.75 | 68.38 |
| 10% bromine cyanogen insect amide suspending agent | 22 grams/acre | 64.37 | 69.29 |
| 20% fipronil bisamide water dispersible granules | 23 grams/acre | 67.13 | 68.14 |
| 200 grams per liter Rynaxypyr suspending agents | 7 grams/acre | 66.48 | 70.02 |
| 15% Tolfenpyrad cream | 45 grams/acre | 65.21 | 69.53 |
| 22% sulfoxaflor suspending agent | 24 grams/acre | 67.39 | 68.75 |
As can be seen from Table 2, fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, chlorine worm benzoyl
Being better than rice hoppers prevention effect after amine, Tolfenpyrad, sulfoxaflor are compounding compareing medicament, the lasting period is long, in test
To rice safety in scope of medication.
Table 3 fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad,
Sulfoxaflor and the mixture preventing and treating wheat aphid test of pesticide effectiveness thereof
As can be seen from Table 3, fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, chlorine worm benzoyl
Being better than Citrus scale insect prevention effect after amine, Tolfenpyrad, sulfoxaflor are compounding compareing medicament, the lasting period is long, in test
To Citrus safety in scope of medication.
Embodiment 19～36 water dispersible granules
Fluorine louse sulfanilamide, effective ingredient B, dispersant, wetting agent, disintegrating agent, filler etc. are needed through comminution by gas stream together
The particle diameter wanted, adds other auxiliary agents such as binding agent, obtains granulation materials.Item is quantitatively sent in fluidized bed granulating dryer
Through pelletizing and dried, preparing fluorine louse sulfanilamide effective ingredient B water dispersible granules product, effective ingredient B includes fluorine pyridine worm acyl
Amine, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, sulfoxaflor one therein.
Table 4 embodiment 19～27 each component and weight portion
Table 5 embodiment 28～36 each component and weight portion
By flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, flonicamid in table
Nitrile exchanges, and can prepare novel formulation.
Table 6 fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad,
Sulfoxaflor and the mixture preventing and treating rice-stem borer test of pesticide effectiveness thereof
| Treatment agent | Preparation dosage | 3 days preventive effects (%) after medicine | 14 days preventive effects (%) after medicine |
| Embodiment 19 | 8 grams/acre | 99.58 | 99.47 |
| Embodiment 20 | 9 grams/acre | 98.94 | 99.62 |
| Embodiment 21 | 12 grams/acre | 98.89 | 98.93 |
| Embodiment 22 | 3 grams/acre | 99.21 | 99.13 |
| Embodiment 23 | 11 grams/acre | 98.64 | 99.24 |
| Embodiment 24 | 4 grams/acre | 98.73 | 99.35 |
| Embodiment 25 | 10 grams/acre | 99.56 | 99.21 |
| Embodiment 26 | 3 grams/acre | 98.85 | 98.68 |
| Embodiment 27 | 7 grams/acre | 97.64 | 97.81 |
| 5% fluorine louse sulfanilamide suspending agent (autogamy) | 24 grams/acre | 65.26 | 69.73 |
| 10% flonicamid water dispersible granules | 45 grams/acre | 64.57 | 69.84 |
| 10% bromine cyanogen insect amide suspending agent | 20 grams/acre | 64.68 | 68.16 |
| 20% fipronil bisamide water dispersible granules | 22 grams/acre | 66.05 | 69.92 |
| 200 grams per liter Rynaxypyr suspending agents | 6 grams/acre | 65.72 | 67.86 |
| 15% Tolfenpyrad cream | 41 grams/acre | 63.24 | 70.15 |
| 22% sulfoxaflor suspending agent | 24 grams/acre | 65.43 | 68.49 |
As can be seen from Table 6, fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, chlorine worm benzoyl
Being better than rice-stem borer prevention effect after amine, Tolfenpyrad, sulfoxaflor are compounding compareing medicament, the lasting period is long, in test
To crop safety in scope of medication.
Table 7 fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad,
Sulfoxaflor and the mixture preventing and treating Laphygma exigua Hubner test of pesticide effectiveness thereof
| Treatment agent | Preparation dosage | 3 days preventive effects (%) after medicine | 14 days preventive effects (%) after medicine |
| Embodiment 28 | 5 grams/acre | 98.47 | 99.38 |
| Embodiment 29 | 6 grams/acre | 99.76 | 98.59 |
| Embodiment 30 | 4 grams/acre | 98.21 | 99.45 |
| Embodiment 31 | 5 grams/acre | 99.58 | 98.39 |
| Embodiment 32 | 6 grams/acre | 98.95 | 99.42 |
| Embodiment 33 | 4 grams/acre | 97.54 | 99.03 |
| Embodiment 34 | 9 grams/acre | 98.29 | 98.84 |
| Embodiment 35 | 11 grams/acre | 99.93 | 99.26 |
| Embodiment 36 | 9 grams/acre | 98.15 | 99.32 |
| 5% fluorine louse sulfanilamide suspending agent (autogamy) | 22 grams/acre | 64.95 | 69.23 |
| 10% flonicamid water dispersible granules | 45 grams/acre | 65.76 | 68.78 |
| 10% bromine cyanogen insect amide suspending agent | 20 grams/acre | 64.24 | 65.15 |
| 20% fipronil bisamide water dispersible granules | 22 grams/acre | 68.47 | 67.11 |
| 200 grams per liter Rynaxypyr suspending agents | 5 grams/acre | 66.31 | 68.24 |
| 15% Tolfenpyrad cream | 41 grams/acre | 68.82 | 70.62 |
| 22% sulfoxaflor suspending agent | 24 grams/acre | 67.29 | 69.83 |
As can be seen from Table 7, fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, chlorine worm benzoyl
Being better than Laphygma exigua Hubner prevention effect after amine, Tolfenpyrad, sulfoxaflor are compounding compareing medicament, the lasting period is long, in examination
Test scope of medication interior to crop safety.
Embodiment 37～56 suspending agent
Fluorine louse sulfanilamide, effective ingredient B, dispersant, wetting agent, defoamer, thickening agent, antifreeze are mixed through high speed shear
Close uniformly, add former medicine, ball milling 2～3 hours in ball mill, make diameter of particle all below 5 μm, deionized water is supplied remaining
Amount, prepares fluorine louse sulfanilamide effective ingredient B suspending agent product, and effective ingredient B includes flonicamid, bromine cyanogen insect amide, fluorine worm
Bisamide, Rynaxypyr, Tolfenpyrad, sulfoxaflor one therein.
Concrete formula is shown in Table 8.
Table 8 embodiment 37～56 each component and weight portion
By flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, flonicamid in table
Nitrile exchanges, and can prepare novel formulation.
Table 9 fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad,
Sulfoxaflor and the mixture preventing and treating Fructus Solani melongenae thrips test of pesticide effectiveness thereof
| Treatment agent | Preparation dosage | 3 days preventive effects (%) after medicine | 14 days preventive effects (%) after medicine |
| Embodiment 37 | 7 grams/acre | 98.56 | 98.59 |
| Embodiment 38 | 6 grams/acre | 99.51 | 99.47 |
| Embodiment 41 | 6 grams/acre | 98.38 | 99.38 |
| Embodiment 42 | 5 grams/acre | 99.24 | 98.16 |
| Embodiment 45 | 6 grams/acre | 98.75 | 99.24 |
| Embodiment 46 | 4 grams/acre | 97.82 | 98.12 |
| Embodiment 49 | 10 grams/acre | 98.16 | 99.03 |
| Embodiment 50 | 3 grams/acre | 99.01 | 99.29 |
| Embodiment 53 | 8 grams/acre | 99.52 | 98.18 |
| Embodiment 55 | 20 grams/acre | 98.38 | 98.56 |
| 5% fluorine louse sulfanilamide suspending agent (autogamy) | 15 grams/acre | 65.51 | 67.02 |
| 10% flonicamid water dispersible granules | 45 grams/acre | 64.19 | 68.55 |
| 10% bromine cyanogen insect amide suspending agent | 20 grams/acre | 66.35 | 67.47 |
| 20% fipronil bisamide water dispersible granules | 22 grams/acre | 65.27 | 64.94 |
| 200 grams per liter Rynaxypyr suspending agents | 8 grams/acre | 66.48 | 68.53 |
| 15% Tolfenpyrad cream | 41 grams/acre | 67.86 | 70.38 |
| 22% sulfoxaflor suspending agent | 24 grams/acre | 65.64 | 71.06 |
As can be seen from Table 9, fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, chlorine worm benzoyl
Being better than Fructus Solani melongenae thrips prevention effect after amine, Tolfenpyrad, sulfoxaflor are compounding compareing medicament, the lasting period is long, uses in test
To crop safety in the range of medicine.
Table 10 fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad,
Sulfoxaflor and the mixture preventing and treating Oryza sativa L. rice leaf roller test of pesticide effectiveness thereof
| Treatment agent | Preparation dosage | 3 days preventive effects (%) after medicine | 14 days preventive effects (%) after medicine |
| Embodiment 39 | 6 grams/acre | 99.31 | 99.25 |
| Embodiment 40 | 5 grams/acre | 98.17 | 98.14 |
| Embodiment 43 | 4 grams/acre | 97.95 | 98.86 |
| Embodiment 44 | 8 grams/acre | 98.26 | 98.37 |
| Embodiment 47 | 6 grams/acre | 99.37 | 99.89 |
| Embodiment 48 | 5 grams/acre | 98.29 | 98.15 |
| Embodiment 51 | 3 grams/acre | 99.06 | 99.32 |
| Embodiment 52 | 4 grams/acre | 99.52 | 99.18 |
| Embodiment 54 | 8 grams/acre | 98.35 | 98.64 |
| Embodiment 56 | 5 grams/acre | 98.34 | 98.47 |
| 5% fluorine louse sulfanilamide suspending agent (autogamy) | 20 grams/acre | 68.96 | 67.12 |
| 10% flonicamid water dispersible granules | 45 grams/acre | 69.25 | 65.36 |
| 10% bromine cyanogen insect amide suspending agent | 22 grams/acre | 65.41 | 70.59 |
| 20% fipronil bisamide water dispersible granules | 27 grams/acre | 64.72 | 71.13 |
| 200 grams per liter Rynaxypyr suspending agents | 6 grams/acre | 65.59 | 70.84 |
| 15% Tolfenpyrad cream | 40 grams/acre | 66.67 | 64.73 |
| 22% sulfoxaflor suspending agent | 25 grams/acre | 64.21 | 67.52 |
As can be seen from Table 10, fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, chlorine worm benzoyl
Being better than Oryza sativa L. rice leaf roller prevention effect after amine, Tolfenpyrad, sulfoxaflor are compounding compareing medicament, the lasting period is long,
To crop safety in test scope of medication.
Embodiment 57～62 suspension emulsion
Effective ingredient B, solvent, emulsifying agent, dispersant are added together, make to be dissolved into homogeneous oil phase；By fluorine louse sulfanilamide,
Water, antifreeze, defoamer etc. mix, and become homogeneous aqueous phase；Under high velocity agitation, aqueous phase is added oil phase or oil phase is added
Entering aqueous phase, prepare fluorine louse sulfanilamide effective ingredient B suspension emulsion product after good dispersion, effective ingredient B includes flonicamid, bromine
Cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, sulfoxaflor one therein.
Concrete formula is shown in Table 11.
Table 11 embodiment 57～62 each component and weight portion
By flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, flonicamid in table
Nitrile exchanges, and can prepare novel formulation.
Table 12 fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad,
Sulfoxaflor and the mixture preventing and treating Brassica campestris L flea beetle test of pesticide effectiveness thereof
| Treatment agent | Preparation dosage | 3 days preventive effects (%) after medicine | 14 days preventive effects (%) after medicine |
| Embodiment 57 | 6 grams/acre | 99.12 | 98.75 |
| Embodiment 58 | 10 grams/acre | 97.57 | 98.24 |
| Embodiment 59 | 4 grams/acre | 99.31 | 99.48 |
| Embodiment 60 | 3 grams/acre | 99.23 | 99.61 |
| Embodiment 61 | 6 grams/acre | 99.38 | 99.26 |
| Embodiment 62 | 7 grams/acre | 98.79 | 99.57 |
| 5% fluorine louse sulfanilamide suspending agent (autogamy) | 17 grams/acre | 65.64 | 69.82 |
| 10% flonicamid water dispersible granules | 40 grams/acre | 66.45 | 68.73 |
| 10% bromine cyanogen insect amide suspending agent | 25 grams/acre | 68.24 | 68.58 |
| 20% fipronil bisamide water dispersible granules | 25 grams/acre | 66.16 | 70.36 |
| 200 grams per liter Rynaxypyr suspending agents | 5 grams/acre | 65.42 | 69.53 |
| 15% Tolfenpyrad cream | 45 grams/acre | 66.28 | 68.64 |
| 22% sulfoxaflor suspending agent | 28 grams/acre | 64.57 | 69.17 |
As can be seen from Table 12, fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, chlorine worm benzoyl
Being better than Brassica campestris L flea beetle prevention effect after amine, Tolfenpyrad, sulfoxaflor are compounding compareing medicament, the lasting period is long, uses in test
To crop safety in the range of medicine.
Embodiment 63～66 aqueous emulsion
Fluorine louse sulfanilamide, effective ingredient B, solvent and emulsifying agent are added together, make to be dissolved into homogeneous oil phase；By water, freeze proof
Agent, defoamer etc. mix, and become homogeneous aqueous phase；Under high velocity agitation, aqueous phase is added oil phase or oil phase is added aqueous phase,
Preparing fluorine louse sulfanilamide flonicamid aqueous emulsion product after good dispersion, effective ingredient B includes flonicamid, bromine cyanogen worm acyl
Amine, fipronil bisamide, Rynaxypyr, Tolfenpyrad, sulfoxaflor one therein.
Concrete formula is shown in Table 13.
Table 9 example 63～66 each component and content
Tolfenpyrad in table is replaced with flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, fluorine
Sulfoxaflor can prepare novel formulation.
Table 14 fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad,
Sulfoxaflor and the mixture preventing and treating Chinese cabbage diamondback moth test of pesticide effectiveness thereof
| Treatment agent | Preparation dosage | 3 days preventive effects (%) after medicine | 14 days preventive effects (%) after medicine |
| Embodiment 63 | 5 grams/acre | 97.58 | 98.04 |
| Embodiment 64 | 7 grams/acre | 98.43 | 99.26 |
| Embodiment 65 | 6 grams/acre | 99.15 | 99.73 |
| Embodiment 66 | 6 grams/acre | 98.27 | 98.89 |
| 5% fluorine louse sulfanilamide suspending agent (autogamy) | 13 grams/acre | 64.72 | 68.31 |
| 10% flonicamid water dispersible granules | 42 grams/acre | 65.46 | 69.17 |
| 10% bromine cyanogen insect amide suspending agent | 28 grams/acre | 64.84 | 70.28 |
| 20% fipronil bisamide water dispersible granules | 20 grams/acre | 66.39 | 68.54 |
| 200 grams per liter Rynaxypyr suspending agents | 10 grams/acre | 67.15 | 70.37 |
| 15% Tolfenpyrad cream | 50 grams/acre | 65.83 | 67.21 |
| 22% sulfoxaflor suspending agent | 25 grams/acre | 66.58 | 69.42 |
As can be seen from Table 14, fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, chlorine worm benzoyl
Being better than Chinese cabbage diamondback moth prevention effect after amine, Tolfenpyrad, sulfoxaflor are compounding compareing medicament, the lasting period is long, in test
To crop safety in scope of medication.
Embodiment 66～71 microcapsule suspending agent
Macromolecule cyst material addition PH regulator is heated to uniform temperature, obtains thick liquid, then dilute,
Form stable prepolymer solution, fluorine louse sulfanilamide, effective ingredient B be dissolved in organic solvent, be then added in prepolymer solution,
Add emulsifying agent, surfactant, and fully shear agitation be dispersed into superfine microgranular, adds PH regulator, and heats up,
Catalyzed polycondensation forms the firm microcapsule being difficult to infiltration, prepares micro-capsule suspension of the present invention, and effective ingredient B includes fluorine
Pyridine insect amide, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, sulfoxaflor one therein.
Concrete formula is shown in Table 15.
Table 15 example 66～71 each component and content
Tolfenpyrad, sulfoxaflor in table are replaced with flonicamid, bromine cyanogen insect amide, fipronil bisamide, chlorine worm
Benzoylamide can prepare novel formulation.
Table 16 fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad,
Sulfoxaflor and mixture thereof prevent and treat the rice hoppers test of pesticide effectiveness
| Treatment agent | Preparation dosage | 3 days preventive effects (%) after medicine | 14 days preventive effects (%) after medicine |
| Embodiment 67 | 10 grams/acre | 98.43 | 99.27 |
| Embodiment 68 | 5 grams/acre | 99.16 | 98.95 |
| Embodiment 69 | 11 grams/acre | 97.39 | 98.21 |
| Embodiment 70 | 4 grams/acre | 98.84 | 99.19 |
| 5% fluorine louse sulfanilamide suspending agent (autogamy) | 15 grams/acre | 68.23 | 70.42 |
| 10% flonicamid water dispersible granules | 40 grams/acre | 65.45 | 68.36 |
| 10% bromine cyanogen insect amide suspending agent | 25 grams/acre | 64.78 | 69.84 |
| 20% fipronil bisamide water dispersible granules | 15 grams/acre | 66.17 | 69.23 |
| 200 grams per liter Rynaxypyr suspending agents | 8 grams/acre | 68.62 | 69.51 |
| 15% Tolfenpyrad cream | 45 grams/acre | 70.21 | 65.47 |
| 22% sulfoxaflor suspending agent | 30 grams/acre | 65.36 | 68.79 |
As can be seen from Table 16, fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, chlorine worm benzoyl
Being better than rice hoppers prevention effect after amine, Tolfenpyrad, sulfoxaflor are compounding compareing medicament, the lasting period is long, in test
Scope of medication is to crop safety.
Embodiment 72～77 microcapsule suspending agents-suspending agent
Use interfacial polymerization, by effective ingredient B, macromolecule cyst material, organic solvent mixing in above-mentioned formula, make molten
Solution uniformly oil phase, oil phase is joined in a shear condition containing emulsifying agent, pH adjusting agent aqueous phase solution in, bi-material
React at oil-water interfaces, around the droplet formation macromolecule cyst wall containing chemical substance, make effective ingredient B microcapsule and hang
Floating agent.By surfactant, defoamer, thickening agent, antifreeze through high speed shear mix homogeneously, add the fluorine former medicine of louse sulfanilamide,
Ball milling 2～3 hours in ball mill, make diameter of particle all below 5 μm, prepares fluorine louse sulfanilamide suspending agent, then will dissolve
Fluorine louse sulfanilamide suspending agent stable in water joins in the aqueous phase solution of effective ingredient B micro-capsule suspension, makes the present invention
Compositions finely disseminated microcapsule suspension-suspendinagent agent product, effective ingredient B includes flonicamid, bromine cyanogen insect amide, fluorine worm pair
Amide, Rynaxypyr, Tolfenpyrad, sulfoxaflor one therein.
Concrete formula is shown in Table 17.
Table 17 embodiment 72～77 each component and weight portion
Flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr in table are replaced with Tolfenpyrad, fluorine
Sulfoxaflor can prepare novel formulation.
Table 18 fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad,
Sulfoxaflor and the mixture preventing and treating apple aphid test of pesticide effectiveness thereof
| Treatment agent | Extension rate | 3 days preventive effects (%) after medicine | 14 days preventive effects (%) after medicine |
| Embodiment 71 | 6500 times | 98.14 | 99.25 |
| Embodiment 72 | 7000 times | 98.76 | 99.01 |
| Embodiment 73 | 6000 times | 97.59 | 98.38 |
| Embodiment 74 | 6000 times | 99.21 | 99.46 |
| 5% fluorine louse sulfanilamide suspending agent (autogamy) | 3000 times | 65.37 | 69.84 |
| 10% flonicamid water dispersible granules | 3000 times | 64.25 | 70.57 |
| 10% bromine cyanogen insect amide suspending agent | 2500 times | 64.72 | 68.69 |
| 20% fipronil bisamide water dispersible granules | 4000 times | 65.13 | 69.78 |
| 200 grams per liter Rynaxypyr suspending agents | 5000 times | 66.49 | 70.23 |
| 15% Tolfenpyrad cream | 2000 times | 65.68 | 68.45 |
| 22% sulfoxaflor suspending agent | 2500 times | 64.34 | 67.66 |
As can be seen from Table 23, fluorine louse sulfanilamide and flonicamid, bromine cyanogen insect amide, fipronil bisamide, chlorine worm benzoyl
Being better than apple aphid prevention effect after amine, Tolfenpyrad, sulfoxaflor are compounding compareing medicament, the lasting period is long, uses in test
To crop safety in the range of medicine.
The embodiment of the present invention is the method using Toxicity Determination and field test to combine.First pass through indoor virulence to survey
Fixed, after clear and definite two kinds of medicaments are compounding by a certain percentage co-toxicity coefficient (CTC), CTC ＜ 80 is antagonism, 80≤CTC≤120
For summation action, CTC ＞ 120 is potentiation, on this basis, then carries out field test.
Test method: respectively the mother solution of each mixed agent is diluted to during test five series concentration, is respectively placed in beaker
Standby.Use the method that first leaching leaf is followed by worm, by the blade of the same size not in contact with any medicament in the medicinal liquid configured
Take out after soaking 5s, naturally dry, put in insect box, then connect for examination larva, raise under the conditions of 25 DEG C, often process 3
Secondary repetition, often repeating examination borer population used is 50, sets blank simultaneously, checks dead borer population in 72h, calculates mortality rate and correction
Mortality rate, tries to achieve virulence regression equation and calculates LC50Value.If comparison mortality rate is more than 10%, then it is considered as invalid test.Calculate public affairs
Formula is as follows:
Insect corrected mortality is converted into probit value (y), and concentration for the treatment of (μ g/ml) is converted into logarithm value (x), with minimum
Square law draws virulence regression equation, and thus calculates the value of every kind of medicament.Common poison system is calculated according to the abundant equation of Sun Yun
Number CTC.Computing formula is following (with fluorine louse sulfanilamide as standard agent, its toxicity index is 100):
TI × the P of the theoretical toxicity index (TTI) of M=fluorine louse sulfanilamideFluorine louse sulfanilamideTI × the P of+effective active composition BEffective active composition B
In formula: M is the mixture of different ratio
PEffective active composition BFor the ratio that effective active composition B is shared in the composition
PFluorine louse sulfanilamideFor the ratio that fluorine louse sulfanilamide is shared in the composition
Note: active component B is selected from any one compound following: flonicamid, bromine cyanogen insect amide, chlorine worm benzoyl
One of amine, fipronil bisamide, Tolfenpyrad, sulfoxaflor are planted.
Application Example two: for examination insect: apple aphid.
Test medicine is provided by Shaanxi Welch Crop Protection Co., Ltd..
EXPERIMENTAL DESIGN: determine fluorine louse sulfanilamide, the former medicine of flonicamid and the two different ratio mixture through pilot study
Effectively lethasl concentration scope.
Toxicity test result one
Table 19 fluorine louse sulfanilamide and the flonicamid different ratio toxicity test to apple aphid
As shown in Table 19, fluorine louse sulfanilamide and flonicamid compound the proportioning of preventing and treating apple aphid when 70: 1 to 1: 70,
Co-toxicity coefficient is all higher than 120, illustrates that both all show potentiation, especially when fluorine louse at mixture in the range of 70: 1 to 1: 70
The proportioning of sulfanilamide and flonicamid is when 10: 1 to 1: 20, and potentiation becomes apparent from highlighting, wherein when fluorine louse sulfanilamide and fluorine
When pyridine insect amide weight ratio is 1: 3, co-toxicity coefficient is maximum, and potentiation is the most obvious, finds simultaneously, fluorine louse sulfanilamide and fluorine pyridine worm
Amide proportioning is 10: 1,9: 1,8: 1,7: 1,6: 1,5: 1,4: 1,3: 1,2: 1,1: 1,1: 2,1: 3,1: 4,1: 5,1: 6,1: 7,1:
8,1: 9,1: 10,1: 11,1: 12,1: 13,1: 14,1: 15,1: 16,1: 17,1: 18,1: 19,1: 20 recurrence of disease at the same time next year pairing fleahopper, viscous
Worm, bollworm, phthorimaea operculella, beet armyworm, diamondback moth, small heart-eating peach worm, applied perfume, striped rice borer, yellow rice borer, rice
Leaf-roller, Pieris rapae, bean-pod borer, planthopper, flea beetle, thrips, aleyrodid, Prodenia litura also have good potentiation, altogether
Poison coefficient is all higher than 200.
Application Example three: for examination insect: rice hoppers.
Test medicine is provided by Shaanxi Welch Crop Protection Co., Ltd..
EXPERIMENTAL DESIGN: determine fluorine louse sulfanilamide, the former medicine of bromine cyanogen insect amide and the two different ratio mixture through pilot study
Effectively lethasl concentration scope.
Toxicity test result two
Table 20 fluorine louse sulfanilamide and the bromine cyanogen insect amide different ratio toxicity test to rice hoppers
As shown in Table 20, fluorine louse sulfanilamide and bromine cyanogen insect amide compound and prevent and treat the proportioning of rice hoppers 70: 1 to 1: 70
Time, co-toxicity coefficient is all higher than 120, illustrates that both all show potentiation at mixtures in the range of 70: 1 to 1: 70, especially when
Fluorine louse sulfanilamide and bromine cyanogen insect amide obtain proportioning when 10: 1 to 1: 20, and potentiation becomes apparent from highlighting, and tests through applicant, when
When fluorine louse sulfanilamide and bromine cyanogen insect amide weight ratio are 1: 3, co-toxicity coefficient is maximum, and potentiation is the most obvious.Find, fluorine louse simultaneously
Sulfanilamide and bromine cyanogen insect amide proportioning are 10: 1,9: 1,8: 1,7: 1,6: 1,5: 1,4: 1,3: 1,2: 1,1: 1,1: 2,1: 3,1: 4,1:
6,1: 7,1: 8,1: 9,1: 10,1: 11,1: 12,1: 13,1: 14,1: 16,1: 17,1: 18,1: 19,1: 20 recurrence of disease at the same time next year pairing fleahopper,
Mythimna separata, bollworm, phthorimaea operculella, beet armyworm, diamondback moth, small heart-eating peach worm, applied perfume, striped rice borer, yellow rice borer,
Rice leaf roller, Pieris rapae, bean-pod borer, planthopper, aphid, flea beetle, thrips, aleyrodid, Prodenia litura also have good potentiation
Effect, co-toxicity coefficient is all higher than 200.
Application Example four: for examination insect: Chinese cabbage diamondback moth.
Test medicine is provided by Shaanxi Welch Crop Protection Co., Ltd..
EXPERIMENTAL DESIGN: determine fluorine louse sulfanilamide, the former medicine of fipronil bisamide and the two different ratio mixture through pilot study
Effectively lethasl concentration scope.
Toxicity test result three
Table 21 fluorine louse sulfanilamide and the fipronil bisamide different ratio toxicity test to Chinese cabbage diamondback moth
As shown in Table 21, fluorine louse sulfanilamide and fipronil bisamide compound the proportioning of preventing and treating Chinese cabbage diamondback moth 70: 1 to 1: 70
Time, co-toxicity coefficient is all higher than 120, illustrates that both all show potentiation at mixtures in the range of 70: 1 to 1: 70, especially when
Fluorine louse sulfanilamide and fipronil bisamide obtain proportioning when 10: 1 to 1: 20, and potentiation becomes apparent from highlighting, and tests through applicant, when
When fluorine louse sulfanilamide and fipronil bisamide weight ratio are 1: 3, co-toxicity coefficient is maximum, and potentiation is the most obvious.Find, fluorine louse simultaneously
Sulfanilamide and fipronil bisamide proportioning are 10: 1,9: 1,8: 1,7: 1,6: 1,5: 1,4: 1,3: 1,2: 1,1: 1,1: 2,1: 3,1: 4,1:
5,1: 6,1: 7,1: 8,1: 9,1: 10,1: 11,1: 12,1: 13,1: 14,1: 15,1: 16,1: 17,1: 18,1: 19,1: 20 recurrence of disease at the same time next year
Pairing fleahopper, mythimna separata, bollworm, phthorimaea operculella, beet armyworm, applied perfume, striped rice borer, yellow rice borer, cnaphalocrocis
Snout moth's larva, Pieris rapae, bean-pod borer, planthopper, aphid, flea beetle, thrips, aleyrodid, Prodenia litura also have good potentiation, altogether poison
Coefficient is all higher than 200.
Application Example five: for examination insect: Oryza sativa L. rice leaf roller.
Test medicine is provided by Shaanxi Welch Crop Protection Co., Ltd..
EXPERIMENTAL DESIGN: determine that fluorine louse sulfanilamide is in the former medicine of Rynaxypyr and the two different ratio mixture through pilot study
Effective lethasl concentration scope.
Toxicity test result four
Table 22 fluorine louse sulfanilamide and the Rynaxypyr different ratio toxicity test to Oryza sativa L. rice leaf roller
As shown in Table 22, fluorine louse sulfanilamide and Rynaxypyr compound the proportioning of preventing and treating Oryza sativa L. rice leaf roller 70: 1 to
When 1: 70, co-toxicity coefficient is all higher than 120, illustrates that both all show potentiation, especially at mixture in the range of 70: 1 to 1: 70
It is that potentiation becomes apparent from highlighting, through applicant when fluorine louse sulfanilamide obtains proportioning 10: 1 to 1: 10 with Rynaxypyr
Test, when fluorine louse sulfanilamide and Rynaxypyr weight ratio are 1: 2, co-toxicity coefficient is maximum, and potentiation is the most obvious.Simultaneously
Finding, fluorine louse sulfanilamide and Rynaxypyr proportioning are 10: 1,9: 1,8: 1,7: 1,6: 1,5: 1,4: 1,3: 1,2: 1,1: 1,1:
2,1: 3,1: 4,1: 5,1: 6,1: 7,1: 8,1: 9,1: 10 recurrence of disease at the same time next year pairing fleahopper, bollworm, phthorimaea operculella, beet armyworm,
Diamondback moth, small heart-eating peach worm, applied perfume, striped rice borer, yellow rice borer, Pieris rapae, bean-pod borer, planthopper, aphid, flea beetle, Ji
Horse, aleyrodid, Prodenia litura also have good potentiation, and co-toxicity coefficient is all higher than 200.
Application Example five: for examination insect: Fructus Solani melongenae thrips.
Test medicine is provided by Shaanxi Welch Crop Protection Co., Ltd..
EXPERIMENTAL DESIGN: determine having of fluorine louse sulfanilamide medicine former with Tolfenpyrad and the two different ratio mixture through pilot study
Effect lethasl concentration scope.
Toxicity test result four
Table 23 fluorine louse sulfanilamide and the Tolfenpyrad different ratio toxicity test to Fructus Solani melongenae thrips
As shown in Table 23, fluorine louse sulfanilamide and Tolfenpyrad compound the proportioning of preventing and treating Fructus Solani melongenae thrips when 70: 1 to 1: 70, altogether
Poison coefficient is all higher than 120, illustrates that both all show potentiation, especially when fluorine louse sulphur at mixture in the range of 70: 1 to 1: 70
Amine and Tolfenpyrad obtain proportioning when 10: 1 to 1: 30, and potentiation becomes apparent from highlighting, and tests through applicant, when fluorine louse sulfanilamide
When being 1: 6 with Tolfenpyrad weight ratio, co-toxicity coefficient is maximum, and potentiation is the most obvious.Find, fluorine louse sulfanilamide and azoles worm simultaneously
Amide proportioning is 10: 1,9: 1,8: 1,7: 1,6: 1,5: 1,4: 1,3: 1,2: 1,1: 1,1: 2,1: 3,1: 4,1: 5,1: 6,1: 7,1:
8,1: 9,1: 10,1: 11,1: 12,1: 13,1: 14,1: 15,1: 16,1: 17,1: 18,1: 19,1: 20,1: 25,1: 30 time compounding
To fleahopper, mythimna separata, bollworm, phthorimaea operculella, beet armyworm, diamondback moth, small heart-eating peach worm, applied perfume, striped rice borer,
Yellow rice borer, rice leaf roller, Pieris rapae, bean-pod borer, planthopper, aphid, Prodenia litura also have good potentiation, altogether poison
Coefficient is all higher than 200.
Application Example five: for examination insect: Cotton Gossypii aleyrodid.
Test medicine is provided by Shaanxi Welch Crop Protection Co., Ltd..
EXPERIMENTAL DESIGN: determine fluorine louse sulfanilamide and the former medicine of sulfoxaflor and the two different ratio mixture through pilot study
Effectively lethasl concentration scope.
Toxicity test result four
Table 24 fluorine louse sulfanilamide and the sulfoxaflor different ratio toxicity test to Cotton Gossypii aleyrodid
As shown in Table 24, fluorine louse sulfanilamide and sulfoxaflor compound the proportioning of preventing and treating Cotton Gossypii aleyrodid when 70: 1 to 1: 70,
Co-toxicity coefficient is all higher than 120, illustrates that both all show potentiation, especially when fluorine louse at mixture in the range of 70: 1 to 1: 70
Sulfanilamide and sulfoxaflor obtain proportioning when 10: 1 to 1: 20, and potentiation becomes apparent from highlighting, and tests through applicant, when fluorine louse
When sulfanilamide and sulfoxaflor weight ratio are 1: 6, co-toxicity coefficient is maximum, and potentiation is the most obvious.Find, fluorine louse sulfanilamide simultaneously
With sulfoxaflor proportioning 10: 1,9: 1,8: 1,7: 1,6: 1,5: 1,4: 1,3: 1,2: 1,1: 1,1: 2,1: 3,1: 4,1: 5,1:
6,1: 7,1: 8,1: 9,1: 10,1: 11,1: 12,1: 13,1: 14,1: 15,1: 16,1: 17,1: 18,1: 19,1: 20 recurrence of disease at the same time next year pairing
Fleahopper, mythimna separata, bollworm, beet armyworm, diamondback moth, small heart-eating peach worm, applied perfume, striped rice borer, yellow rice borer, cnaphalocrocis
Snout moth's larva, Pieris rapae, bean-pod borer, planthopper, aphid, flea beetle, thrips, Prodenia litura also have good potentiation, co-toxicity coefficient
It is all higher than 200.
Claims (4)
1. the Pesticidal combination of a fluorine-containing louse sulfanilamide, it is characterised in that: effective active composition is active components A and active component
B, active components A is 10:1 ~ 1:20 with the weight ratio of active component B, and described active components A is fluorine louse sulfanilamide, active component B
For sulfoxaflor.
The Pesticidal combination of fluorine-containing louse sulfanilamide the most according to claim 1, it is characterised in that: compositions makes wettable powder
Agent, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspending agent-suspending agent.
The Pesticidal combination of fluorine-containing louse sulfanilamide the most according to claim 2 is for preventing and treating the purposes of crop pest.
Purposes the most according to claim 3, it is characterised in that described insect is fleahopper, mythimna separata, bollworm, Rhizoma Solani tuber osi
Tuber moth, beet armyworm, diamondback moth, small heart-eating peach worm, applied perfume, striped rice borer, yellow rice borer, rice leaf roller, Pieris rapae,
Bean-pod borer, planthopper, aphid, flea beetle, thrips, aleyrodid, Prodenia litura.
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| CN201210116351.XA CN103371164B (en) | 2012-04-19 | 2012-04-19 | A kind of Pesticidal combination of fluorine-containing louse sulfanilamide |
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| CN101647460A (en) * | 2009-07-21 | 2010-02-17 | 深圳诺普信农化股份有限公司 | Pesticide composition with synergetic effect |
| CN101700024A (en) * | 2009-08-01 | 2010-05-05 | 深圳诺普信农化股份有限公司 | Synergistic pesticide composition and application thereof |
| JP5706179B2 (en) * | 2010-08-20 | 2015-04-22 | 住友化学株式会社 | Harmful arthropod control composition and harmful arthropod control method |
| CN103300000B (en) * | 2012-03-12 | 2016-04-06 | 陕西韦尔奇作物保护有限公司 | A kind of Pesticidal combination containing ring worm hydrazides and amide-type |
| CN105994270A (en) * | 2012-03-12 | 2016-10-12 | 陕西韦尔奇作物保护有限公司 | Chromafenozide-containing insecticidal composition |
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Address after: 715500 Pucheng Shaanxi chemical base industrial park, Shaanxi, Weinan Patentee after: Shaanxi yitianfeng crop Technology Co.,Ltd. Address before: 715500 Pucheng Shaanxi chemical base industrial park, Shaanxi, Weinan Patentee before: Shaanxi Welch Crop Protection Co.,Ltd. |
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