CN103371164A - Insecticidal composition containing fluorine lice sulfanilamide - Google Patents
Insecticidal composition containing fluorine lice sulfanilamide Download PDFInfo
- Publication number
- CN103371164A CN103371164A CN201210116351XA CN201210116351A CN103371164A CN 103371164 A CN103371164 A CN 103371164A CN 201210116351X A CN201210116351X A CN 201210116351XA CN 201210116351 A CN201210116351 A CN 201210116351A CN 103371164 A CN103371164 A CN 103371164A
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- CN
- China
- Prior art keywords
- fluorine
- lice sulfanilamide
- acres
- weight ratio
- flonicamid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 title claims abstract description 223
- 229940124530 sulfonamide Drugs 0.000 title claims abstract description 223
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 title claims abstract description 114
- 229910052731 fluorine Inorganic materials 0.000 title claims abstract description 114
- 239000011737 fluorine Substances 0.000 title claims abstract description 114
- 241001674048 Phthiraptera Species 0.000 title claims abstract description 113
- 239000000203 mixture Substances 0.000 title claims abstract description 41
- 230000000749 insecticidal effect Effects 0.000 title abstract description 9
- 239000005900 Flonicamid Substances 0.000 claims abstract description 62
- PSOVNZZNOMJUBI-UHFFFAOYSA-N chlorantraniliprole Chemical compound CNC(=O)C1=CC(Cl)=CC(C)=C1NC(=O)C1=CC(Br)=NN1C1=NC=CC=C1Cl PSOVNZZNOMJUBI-UHFFFAOYSA-N 0.000 claims abstract description 62
- RLQJEEJISHYWON-UHFFFAOYSA-N flonicamid Chemical compound FC(F)(F)C1=CC=NC=C1C(=O)NCC#N RLQJEEJISHYWON-UHFFFAOYSA-N 0.000 claims abstract description 62
- WPALTCMYPARVNV-UHFFFAOYSA-N tolfenpyrad Chemical compound CCC1=NN(C)C(C(=O)NCC=2C=CC(OC=3C=CC(C)=CC=3)=CC=2)=C1Cl WPALTCMYPARVNV-UHFFFAOYSA-N 0.000 claims abstract description 60
- 241000607479 Yersinia pestis Species 0.000 claims abstract description 10
- 241000238631 Hexapoda Species 0.000 claims description 81
- 150000001408 amides Chemical class 0.000 claims description 60
- ZOCSXAVNDGMNBV-UHFFFAOYSA-N 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile Chemical compound NC1=C(S(=O)C(F)(F)F)C(C#N)=NN1C1=C(Cl)C=C(C(F)(F)F)C=C1Cl ZOCSXAVNDGMNBV-UHFFFAOYSA-N 0.000 claims description 59
- 239000005899 Fipronil Substances 0.000 claims description 59
- YBOFEONRFJMHND-UHFFFAOYSA-N [Br].N#CC#N Chemical compound [Br].N#CC#N YBOFEONRFJMHND-UHFFFAOYSA-N 0.000 claims description 59
- 229940013764 fipronil Drugs 0.000 claims description 59
- FTQWRYSLUYAIRQ-UHFFFAOYSA-N n-[(octadecanoylamino)methyl]octadecanamide Chemical compound CCCCCCCCCCCCCCCCCC(=O)NCNC(=O)CCCCCCCCCCCCCCCCC FTQWRYSLUYAIRQ-UHFFFAOYSA-N 0.000 claims description 59
- BAOWVDHYZBLYMB-UHFFFAOYSA-N [F].C1=CC=NC=C1 Chemical compound [F].C1=CC=NC=C1 BAOWVDHYZBLYMB-UHFFFAOYSA-N 0.000 claims description 58
- -1 amine nitrile Chemical class 0.000 claims description 57
- 239000000375 suspending agent Substances 0.000 claims description 55
- 239000004562 water dispersible granule Substances 0.000 claims description 24
- 239000003094 microcapsule Substances 0.000 claims description 15
- 241000008892 Cnaphalocrocis patnalis Species 0.000 claims description 13
- 241000500437 Plutella xylostella Species 0.000 claims description 13
- 241001414989 Thysanoptera Species 0.000 claims description 13
- 239000000839 emulsion Substances 0.000 claims description 12
- 230000000361 pesticidal effect Effects 0.000 claims description 12
- 241000426497 Chilo suppressalis Species 0.000 claims description 11
- 241000256247 Spodoptera exigua Species 0.000 claims description 11
- 239000000725 suspension Substances 0.000 claims description 11
- 241001486250 Etiella zinckenella Species 0.000 claims description 9
- 241000255967 Helicoverpa zea Species 0.000 claims description 9
- 241000255969 Pieris brassicae Species 0.000 claims description 9
- 241000176086 Sogatella furcifera Species 0.000 claims description 9
- 241000985245 Spodoptera litura Species 0.000 claims description 9
- 241001124076 Aphididae Species 0.000 claims description 8
- 241001347511 Carposina sasakii Species 0.000 claims description 8
- 241000738498 Epitrix pubescens Species 0.000 claims description 8
- 241000409991 Mythimna separata Species 0.000 claims description 8
- 241001439019 Phthorimaea operculella Species 0.000 claims description 8
- 239000000843 powder Substances 0.000 claims description 6
- 238000009736 wetting Methods 0.000 claims description 6
- 241000220225 Malus Species 0.000 claims description 4
- 239000004530 micro-emulsion Substances 0.000 claims description 4
- 241000665051 Chilo sacchariphagus indicus Species 0.000 claims 1
- 239000000575 pesticide Substances 0.000 abstract description 13
- 230000000694 effects Effects 0.000 abstract description 6
- 239000005886 Chlorantraniliprole Substances 0.000 abstract description 3
- 235000013399 edible fruits Nutrition 0.000 abstract description 3
- 239000000835 fiber Substances 0.000 abstract description 3
- 238000001228 spectrum Methods 0.000 abstract description 3
- 235000013311 vegetables Nutrition 0.000 abstract description 3
- 239000005889 Cyantraniliprole Substances 0.000 abstract description 2
- 239000005901 Flubendiamide Substances 0.000 abstract description 2
- 239000005934 Sulfoxaflor Substances 0.000 abstract description 2
- ZVQOOHYFBIDMTQ-UHFFFAOYSA-N [methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-lambda(6)-sulfanylidene]cyanamide Chemical compound N#CN=S(C)(=O)C(C)C1=CC=C(C(F)(F)F)N=C1 ZVQOOHYFBIDMTQ-UHFFFAOYSA-N 0.000 abstract description 2
- DVBUIBGJRQBEDP-UHFFFAOYSA-N cyantraniliprole Chemical compound CNC(=O)C1=CC(C#N)=CC(C)=C1NC(=O)C1=CC(Br)=NN1C1=NC=CC=C1Cl DVBUIBGJRQBEDP-UHFFFAOYSA-N 0.000 abstract description 2
- ZGNITFSDLCMLGI-UHFFFAOYSA-N flubendiamide Chemical compound CC1=CC(C(F)(C(F)(F)F)C(F)(F)F)=CC=C1NC(=O)C1=CC=CC(I)=C1C(=O)NC(C)(C)CS(C)(=O)=O ZGNITFSDLCMLGI-UHFFFAOYSA-N 0.000 abstract description 2
- 235000013305 food Nutrition 0.000 abstract description 2
- 206010059866 Drug resistance Diseases 0.000 abstract 1
- 244000144972 livestock Species 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 59
- 238000012360 testing method Methods 0.000 description 33
- 239000002131 composite material Substances 0.000 description 32
- 230000002195 synergetic effect Effects 0.000 description 29
- 239000004480 active ingredient Substances 0.000 description 21
- 230000003449 preventive effect Effects 0.000 description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 18
- 241000209094 Oryza Species 0.000 description 13
- 235000007164 Oryza sativa Nutrition 0.000 description 13
- 239000003795 chemical substances by application Substances 0.000 description 13
- 235000009566 rice Nutrition 0.000 description 13
- 238000002360 preparation method Methods 0.000 description 12
- 231100000820 toxicity test Toxicity 0.000 description 12
- 229940079593 drug Drugs 0.000 description 11
- 230000002045 lasting effect Effects 0.000 description 11
- 239000013530 defoamer Substances 0.000 description 10
- 239000002270 dispersing agent Substances 0.000 description 10
- 239000003995 emulsifying agent Substances 0.000 description 10
- 238000009472 formulation Methods 0.000 description 10
- 230000010165 autogamy Effects 0.000 description 9
- 241001249129 Scirpophaga incertulas Species 0.000 description 8
- 230000002528 anti-freeze Effects 0.000 description 8
- 239000000470 constituent Substances 0.000 description 8
- 239000012071 phase Substances 0.000 description 8
- 239000002917 insecticide Substances 0.000 description 7
- 239000000126 substance Substances 0.000 description 7
- 239000002562 thickening agent Substances 0.000 description 7
- 239000000080 wetting agent Substances 0.000 description 7
- 239000003905 agrochemical Substances 0.000 description 6
- 238000002474 experimental method Methods 0.000 description 6
- 231100000636 lethal dose Toxicity 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 239000004094 surface-active agent Substances 0.000 description 6
- 241000273311 Aphis spiraecola Species 0.000 description 5
- 235000010149 Brassica rapa subsp chinensis Nutrition 0.000 description 5
- 235000000536 Brassica rapa subsp pekinensis Nutrition 0.000 description 5
- 241000499436 Brassica rapa subsp. pekinensis Species 0.000 description 5
- 206010011732 Cyst Diseases 0.000 description 5
- 244000061458 Solanum melongena Species 0.000 description 5
- 235000002597 Solanum melongena Nutrition 0.000 description 5
- 208000031513 cyst Diseases 0.000 description 5
- 239000008367 deionised water Substances 0.000 description 5
- 229910021641 deionized water Inorganic materials 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 229920002521 macromolecule Polymers 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 239000002904 solvent Substances 0.000 description 5
- 239000003513 alkali Substances 0.000 description 4
- 239000000945 filler Substances 0.000 description 4
- 239000003960 organic solvent Substances 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 231100000419 toxicity Toxicity 0.000 description 4
- 230000001988 toxicity Effects 0.000 description 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- 229920000742 Cotton Polymers 0.000 description 3
- 239000013543 active substance Substances 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 3
- 239000006185 dispersion Substances 0.000 description 3
- 230000008595 infiltration Effects 0.000 description 3
- 238000001764 infiltration Methods 0.000 description 3
- 239000003002 pH adjusting agent Substances 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000003381 stabilizer Substances 0.000 description 3
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 2
- 241000675108 Citrus tangerina Species 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 241000255777 Lepidoptera Species 0.000 description 2
- 241000124008 Mammalia Species 0.000 description 2
- 241001180370 Psylliodes chrysocephalus Species 0.000 description 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 2
- 230000008485 antagonism Effects 0.000 description 2
- 239000008346 aqueous phase Substances 0.000 description 2
- 238000000498 ball milling Methods 0.000 description 2
- 229910001424 calcium ion Inorganic materials 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 230000003750 conditioning effect Effects 0.000 description 2
- 239000007884 disintegrant Substances 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 231100000225 lethality Toxicity 0.000 description 2
- 230000003151 ovacidal effect Effects 0.000 description 2
- JMANVNJQNLATNU-UHFFFAOYSA-N oxalonitrile Chemical compound N#CC#N JMANVNJQNLATNU-UHFFFAOYSA-N 0.000 description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 2
- 230000001018 virulence Effects 0.000 description 2
- 229910014265 BrCl Inorganic materials 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 description 1
- QQKGNOCPSSMOBE-UHFFFAOYSA-N FC(C1=CC=C(C=N1)C(C)C[O])(F)F Chemical compound FC(C1=CC=C(C=N1)C(C)C[O])(F)F QQKGNOCPSSMOBE-UHFFFAOYSA-N 0.000 description 1
- 241000258937 Hemiptera Species 0.000 description 1
- 238000012695 Interfacial polymerization Methods 0.000 description 1
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 206010034133 Pathogen resistance Diseases 0.000 description 1
- 241000125167 Rhopalosiphum padi Species 0.000 description 1
- 229930001406 Ryanodine Natural products 0.000 description 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000000895 acaricidal effect Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 238000012271 agricultural production Methods 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000012752 auxiliary agent Substances 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000006555 catalytic reaction Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 229960001231 choline Drugs 0.000 description 1
- 239000007957 coemulsifier Substances 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- ZHNUHDYFZUAESO-UHFFFAOYSA-N formamide Substances NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000012452 mother liquor Substances 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 231100000194 ovacidal Toxicity 0.000 description 1
- 230000017448 oviposition Effects 0.000 description 1
- 230000010627 oxidative phosphorylation Effects 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- NAYYNDKKHOIIOD-UHFFFAOYSA-N phthalamide Chemical compound NC(=O)C1=CC=CC=C1C(N)=O NAYYNDKKHOIIOD-UHFFFAOYSA-N 0.000 description 1
- 238000006068 polycondensation reaction Methods 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 102000005962 receptors Human genes 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- JJSYXNQGLHBRRK-SFEDZAPPSA-N ryanodine Chemical compound O([C@@H]1[C@]([C@@]2([C@]3(O)[C@]45O[C@@]2(O)C[C@]([C@]4(CC[C@H](C)[C@H]5O)O)(C)[C@@]31O)C)(O)C(C)C)C(=O)C1=CC=CN1 JJSYXNQGLHBRRK-SFEDZAPPSA-N 0.000 description 1
- 102000042094 ryanodine receptor (TC 1.A.3.1) family Human genes 0.000 description 1
- 108091052345 ryanodine receptor (TC 1.A.3.1) family Proteins 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 210000002460 smooth muscle Anatomy 0.000 description 1
- 210000002948 striated muscle cell Anatomy 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 239000011708 vitamin B3 Substances 0.000 description 1
- 235000019160 vitamin B3 Nutrition 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N41/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
- A01N41/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom containing a sulfur-to-oxygen double bond
- A01N41/04—Sulfonic acids; Derivatives thereof
- A01N41/06—Sulfonic acid amides
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N41/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
- A01N41/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom containing a sulfur-to-oxygen double bond
- A01N41/10—Sulfones; Sulfoxides
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses an insecticidal composition containing fluorine lice sulfanilamide. The insecticidal composition comprises an active component A and an active component B, wherein the active component A adopts the fluorine lice sulfanilamide; the active component B is one of flonicamid, cyantraniliprole, chlorantraniliprole, flubendiamide, tolfenpyrad and sulfoxaflor; the weight ratio of the active component A to the active component B is 1:70 to 70:1. The composition disclosed by the invention can prevent and treat multiple pests and has an obvious synergism effect; the insecticidal spectrum is expanded; the insecticidal composition is high in activity to multiple pests on vegetables, fruit trees, food crops and fiber crops; the using amount of pesticides is reduced; the residual amount of the pesticides on the crops is reduced; the environment pollution is alleviated; the insecticidal composition is safe to human and livestock and high in environment compatibility, and the pests are unlikely to generate the drug resistance.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of Pesticidal combination of fluorine-containing lice sulfanilamide (SN).
Background technology
Flonicamid (flonicamid) chemical name: N-cyanogen methyl-4-(trifluoromethyl) vitamin PP, molecular formula: C
9H
6F
3N
3O, flonicamid is effective to various suckings pest, and has good osmosis.It can be from root to stem, the infiltration of leaf section, but by leaf section to stem, root osmosis relatively a little less than.This medicament causes effect by hindering the insect act of sucking.Insect stops to suck after taking in medicament very soon, and is last hungry and dead.
Bromine cyanogen insect amide (Cyantraniliprole), molecular formula: C
19H
14BrClN
6O
2The bromine cyanogen insect amide is the second generation ryanodine receptor inhibitor insecticides of E.I.Du Pont Company's develop after chlorantraniliprole, cyanogen insect amide is to form by the various polar groups that change on the phenyl ring, have more efficient, applicable crops is more extensive, can effectively prevent and treat Lepidoptera, Semiptera and coleopteran pest.
Rynaxypyr (chlorantraniliprole) chemical name: 3-bromo-N-[4-chloro-2-methyl-6-[(methyl-carbamoyl) benzene]-1-(3-chloropyridine-2-yl)-1-hydrogen-pyridine-5-formamide, molecular formula: C
18H
14N
5O
2BrCl
2, Rynaxypyr belongs to the O-formammidotiazol-benzamide insecticide.Mainly be to activate blue Buddhist nun's alkali acceptor, discharge the calcium ion of storing in smooth muscle and the striated muscle cell, cause that the muscle adjusting is weak, paralysis is until last insect is dead.This active ingredient shows mammal and the extremely significant selective difference of the blue Buddhist nun's alkali of insect acceptor, has greatly improved mammal and other vertebrate safeties.
Fipronil bisamide (flubendiamide) chemical name: 3-iodo-N '-(2-mesyl-1,1-dimethyl ethyl group-N-{4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl) ethyl]-the O-tolyl } phthalamide, molecular formula: C
23H
22F
7IN
2O
4S, fipronil bisamide belong to Novel ortho benzenedicarboxamide insecticides, activate calcium release channel in blue Buddhist nun's alkali recipient cell, the property out of control release that causes storing calcium ion.It is the compound that acts on blue Buddhist nun's alkali (Ryanodine) acceptor of insect cell at present few in number.Lepidoptera pest there is the spectrum preventive effect, produces without cross resistance with existing insecticide, be suitable for very much the control that existing insecticide produces the insect of resistance.Larva there is very outstanding preventive effect, limited to the adult preventive effect, there is not ovicidal action.Slightly conduct by xylem after in the infiltration plant body.Resistance of rainwater washing against.
Tolfenpyrad (tolfenpyrad) chemical name: 4-chloro-3-ethyl-1-methyl-N-[4-(p-tolyl oxygen base) phenyl] pyrazoles-5-acid amides, molecular formula: C
21H
22ClN
3O
2Tolfenpyrad is the novel pyrazole heterocyclic insecticidal/acaricidal agent of former Mitsubishi chemical company (its agricultural chemicals partly now belong to Japanese agricultural chemicals company) exploitation, its main mechanism is the oxidative phosphorylation that stops insect, also has ovicidal, presses down food, oviposition deterrence and bactericidal action.
Fluorine pyridine worm amine nitrile, English common name (sulfoxaflor), molecular formula: C
10H
10F
3N
3OS chemical name: [1-[6-(trifluoromethyl) pyridin-3-yl] ethyl] methyl (oxygen)-λ 4-sulfydryl cyanamide.Fluorine pyridine worm amine nitrile is an insecticide of sulfimide, and sulfimide acts on the nervous system of insect, namely acts on binding site unique in the choline receptor and brings into play insecticidal function.Can be through leaf, stem, root absorption and enter in the plant corpus.
Yet in the real process of agricultural production, the pest control problem of easy generation is the generation of pest resistance to insecticide.The different cultivars composition carries out composite, is the very common method of control resistant insect.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and, antagonism.In most cases, the composite effect of agricultural chemicals all is additive effect, and the seldom composite of synergistic effect really arranged, especially synergistic effect very obviously, co-toxicity coefficient very high composite just still less.Through inventor's research, can produce good synergistic effect after discovery is composite with fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, Rynaxypyr, fipronil bisamide, Tolfenpyrad, fluorine pyridine worm amine nitrile, and not yet open about the composite relevant report of fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, Rynaxypyr, fipronil bisamide, Tolfenpyrad, fluorine pyridine worm amine nitrile.
Summary of the invention
Degradation problem under the resistance generation that the long-term use of single dose may bring, the drug effect, the Pesticidal combination that the present invention proposes contains active components A and active component B, and an amount of surfactant and carrier.
A kind of Pesticidal combination of fluorine-containing lice sulfanilamide (SN), it is characterized in that: contain active components A and active component B, the weight ratio of active components A and active component B is 1: 70～70: 1, described active components A is selected from fluorine lice sulfanilamide (SN), active component B is selected from a kind of in flonicamid, bromine cyanogen insect amide, Rynaxypyr, fipronil bisamide, Tolfenpyrad, the fluorine pyridine worm amine nitrile, the weight ratio of active components A and active component B is preferably 1: 50～and 30: 1, the weight ratio of fluorine lice sulfanilamide (SN) and flonicamid more preferably 10: 1～1: 20; The weight ratio of fluorine lice sulfanilamide (SN) and bromine cyanogen insect amide more preferably 10: 1～1: 20; The weight ratio of fluorine lice sulfanilamide (SN) and Rynaxypyr more preferably 10: 1～1: 10; The weight ratio of fluorine lice sulfanilamide (SN) and fipronil bisamide more preferably 10: 1～1: 20; The weight ratio of fluorine lice sulfanilamide (SN) and Tolfenpyrad more preferably 10: 1～1: 30; The weight ratio of fluorine lice sulfanilamide (SN) and fluorine pyridine worm amine nitrile more preferably 10: 1～1: 30.
The Pesticidal combination of described fluorine-containing lice sulfanilamide (SN) is used for the purposes of control crop pest, and described crops comprise the purposes of insect on vegetables, fruit tree, cereal crops, the fiber crop.
Described purposes, it is characterized in that described insect comprises: fleahopper, mythimna separata, cotton bollworm, potato tuberworm, beet armyworm, diamond-back moth, peach fruit borer, apple olethreutid, striped rice borer, paddy stem borer, rice leaf roller, cabbage caterpillar, lima bean pod borer, rice fulgorid, aphid, flea beetle, thrips, aleyrodid, prodenia litura.
The weight ratio of active components A and active component B is 1: 70～70: 1.Usually the weight percentage of active component is 1%～90% of gross weight in the composition, and better is 5%～85%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains by weight 1%～70% active substance, preferably is 5%～50%; Solid pharmaceutical preparation contains by weight 5%～85% active substance, preferably is 10%～70%.
At least contain a kind of surfactant in the Pesticidal combination of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5%～40% of total formulation weight amount, and surplus is solid or liquid diluent.
Composition of the present invention can be by the user before use through dilution or directly use.Its preparation can be by common processing method preparation known in those skilled in the art, after being about to active substance and liquid flux or solid carrier mixing, add again one or more in surfactant such as dispersant, stabilizing agent, wetting agent, emulsifier, binding agent, the defoamer etc.
Pesticidal combination of the present invention, can be processed on demand acceptable formulation on any agricultural chemicals, wherein the excellent formulation of selecting is: wetting powder, suspending agent, suspension emulsion, water dispersible granules, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspending agent-suspending agent.
When making wetting powder, composition comprises following constituent content: active components A 1%～70%, active component B1%～70%, dispersant 1.5%～10%, wetting agent 1%～10%, filler surplus.
When making water dispersible granules, composition comprises following constituent content: active components A 1%～70%, active component B1%～70%, dispersant 1%～12%, wetting agent 1%～8%, disintegrant 1%～10%, binding agent 0%～8%, filler surplus.
Comprise following constituent content when composition is made suspending agent: active components A 1%～50%, active component B1%～50%, dispersant 1%～10%, wetting agent 1%～10%, defoamer 0.1%～1%, thickener 0.01%～2%, antifreeze 0%～8%, deionized water add to 100%.
Comprise following constituent content when composition is made suspension emulsion: active components A 1%～50%, active component B1%～50%, solvent 0～15%, emulsifier 2%～12%, dispersant 2%～10%, defoamer 0.1%～2%, thickener 0.01%～2%, antifreeze 0%～8%, stabilizing agent 0%～3%, water add to 100%.
Comprise following constituent content when composition is made aqueous emulsion: active components A 1%～50%, active component B1%～50%, solvent 1%～30%, emulsifier 1%～20%, co-emulsifier 1%～8%, antifreeze 0%～8%, thickener 0.05%～2%, defoamer 0%～2%, deionized water are supplied surplus.
Comprise following constituent content when composition is made microemulsion: active components A 1%～50%, active component B1%～50%, solvent 1%～30%, emulsifier 5%～20%, antifreeze 0%～8%, thickener 0.01%～2%, defoamer 0.01%～2%, stabilizing agent 0%～4%, deionized water is supplied surplus.
When making microcapsule suspending agent, composition comprises following constituent content: active components A 1%～50%, active component B1%～50%, macromolecule cyst material 3%～10%, dispersant 2%～10%, organic solvent 0%～10%, emulsifier 2%～7%, pH adjusting agent 0.1%～5%, deionized water adds to 100%.
Composition comprises following constituent content when making microcapsule suspension-suspending agent: active components A 1%～40%, active component B1%～60%, macromolecule cyst material 2%～12%, surfactant 3%～15%, organic solvent 1%～5%, emulsifier 1%～6%, defoamer 0.01%～5%, thickener 0.05%～1%, pH adjusting agent 0.01%～5%, water add to 100%.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension of the present invention-suspending agent the key technical indexes:
The invention has the advantages that:
(1) fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, Rynaxypyr, fipronil bisamide, Tolfenpyrad, fluorine pyridine worm amine nitrile composite after, have notable synergistic and lasting effect;
(2) enlarged insecticidal spectrum, the fleahopper on vegetables, fruit tree, cereal crops, the fiber crop, mythimna separata, cotton bollworm, potato tuberworm, beet armyworm, diamond-back moth, peach fruit borer, apple olethreutid, striped rice borer, paddy stem borer, rice leaf roller, cabbage caterpillar, lima bean pod borer, rice fulgorid, aphid, flea beetle, thrips, aleyrodid, prodenia litura etc. have all been had greater activity; (3) reduce the dosage of agricultural chemicals, reduced the residual quantity of agricultural chemicals on crop; (4) to the person poultry safety, Environmental compatibility is good, and insect is difficult for developing immunity to drugs.
Embodiment
To further instruction of the present invention, the percentage among the embodiment all is weight percentage below in conjunction with embodiment, but the present invention is not limited thereto.
Application Example one
Embodiment 1～18 wetting powder
Fluorine lice sulfanilamide (SN), active ingredient B, dispersant, wetting agent, filler are mixed in mixed cylinder, after pulverizing, airslide disintegrating mill mixes again, namely can be made into fluorine lice sulfanilamide (SN) active ingredient B wetting powder product, active ingredient B comprises wherein a kind of of flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile.
Concrete prescription sees Table 1.
Table 1 embodiment 1～18 each component and weight portion
Flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile exchange in will showing, and can make novel formulation.
Table 2 fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile and be mixed and prevent and treat the rice hoppers test of pesticide effectiveness
| Treatment agent | The preparation dosage | 3 days preventive effects (%) behind the medicine | 14 days preventive effects (%) behind the medicine |
| Embodiment 1 | 4 g/acres | 99.43 | 98.25 |
| Embodiment 2 | 3 g/acres | 98.75 | 99.17 |
| Embodiment 5 | 10 g/acres | 98.59 | 99.02 |
| Embodiment 6 | 6 g/acres | 99.35 | 98.86 |
| Embodiment 9 | 11 g/acres | 99.16 | 98.54 |
| Embodiment 10 | 5 g/acres | 99.24 | 98.87 |
| Embodiment 13 | 3 g/acres | 99.08 | 99.49 |
| Embodiment 15 | 7 g/acres | 98.87 | 98.95 |
| Embodiment 17 | 6 g/acres | 99.31 | 98.72 |
| 5% fluorine lice sulfanilamide (SN) suspending agent (autogamy) | 15 g/acres | 67.59 | 70.23 |
| 10% flonicamid water dispersible granules | 40 g/acres | 65.75 | 68.38 |
| 10% bromine cyanogen insect amide suspending agent | 22 g/acres | 64.37 | 69.29 |
| 20% fipronil bisamide water dispersible granules | 23 g/acres | 67.13 | 68.14 |
| 200 grams per liter Rynaxypyr suspending agents | 7 g/acres | 66.48 | 70.02 |
| 15% Tolfenpyrad missible oil | 45 g/acres | 65.21 | 69.53 |
| 22% fluorine pyridine worm amine nitrile suspending agent | 24 g/acres | 67.39 | 68.75 |
As can be seen from Table 2, fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile are composite to be better than contrasting medicament afterwards to the rice hoppers control efficiency, lasting period is long, the test scope of medication in to rice safety.
Table 3 fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile and the control wheat aphid test of pesticide effectiveness that is mixed thereof
As can be seen from Table 3, fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile are composite to be better than contrasting medicament afterwards to oranges and tangerines scale insect control efficiency, lasting period is long, the test scope of medication in to oranges and tangerines safety.
Embodiment 19～36 water dispersible granules
Fluorine lice sulfanilamide (SN), active ingredient B, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through air-flow crushing together, add again other auxiliary agents such as binding agent, obtain the materials of granulating.Item is quantitatively sent in the fluidized bed granulation dryer through after granulation and the drying, make fluorine lice sulfanilamide (SN) active ingredient B water dispersible granules product, active ingredient B comprises wherein a kind of of flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile.
Table 4 embodiment 19～27 each component and weight portions
Table 5 embodiment 28～36 each component and weight portions
Flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile exchange in will showing, and can make novel formulation.
Table 6 fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile and the control rice-stem borer test of pesticide effectiveness that is mixed thereof
| Treatment agent | The preparation dosage | 3 days preventive effects (%) behind the medicine | 14 days preventive effects (%) behind the medicine |
| Embodiment 19 | 8 g/acres | 99.58 | 99.47 |
| Embodiment 20 | 9 g/acres | 98.94 | 99.62 |
| Embodiment 21 | 12 g/acres | 98.89 | 98.93 |
| Embodiment 22 | 3 g/acres | 99.21 | 99.13 |
| Embodiment 23 | 11 g/acres | 98.64 | 99.24 |
| Embodiment 24 | 4 g/acres | 98.73 | 99.35 |
| Embodiment 25 | 10 g/acres | 99.56 | 99.21 |
| Embodiment 26 | 3 g/acres | 98.85 | 98.68 |
| Embodiment 27 | 7 g/acres | 97.64 | 97.81 |
| 5% fluorine lice sulfanilamide (SN) suspending agent (autogamy) | 24 g/acres | 65.26 | 69.73 |
| 10% flonicamid water dispersible granules | 45 g/acres | 64.57 | 69.84 |
| 10% bromine cyanogen insect amide suspending agent | 20 g/acres | 64.68 | 68.16 |
| 20% fipronil bisamide water dispersible granules | 22 g/acres | 66.05 | 69.92 |
| 200 grams per liter Rynaxypyr suspending agents | 6 g/acres | 65.72 | 67.86 |
| 15% Tolfenpyrad missible oil | 41 g/acres | 63.24 | 70.15 |
| 22% fluorine pyridine worm amine nitrile suspending agent | 24 g/acres | 65.43 | 68.49 |
As can be seen from Table 6, fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile are composite to be better than contrasting medicament afterwards to the rice-stem borer control efficiency, lasting period is long, the test scope of medication in to crop safety.
Table 7 fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile and the control Laphygma exigua Hubner test of pesticide effectiveness that is mixed thereof
| Treatment agent | The preparation dosage | 3 days preventive effects (%) behind the medicine | 14 days preventive effects (%) behind the medicine |
| Embodiment 28 | 5 g/acres | 98.47 | 99.38 |
| Embodiment 29 | 6 g/acres | 99.76 | 98.59 |
| Embodiment 30 | 4 g/acres | 98.21 | 99.45 |
| Embodiment 31 | 5 g/acres | 99.58 | 98.39 |
| Embodiment 32 | 6 g/acres | 98.95 | 99.42 |
| Embodiment 33 | 4 g/acres | 97.54 | 99.03 |
| Embodiment 34 | 9 g/acres | 98.29 | 98.84 |
| Embodiment 35 | 11 g/acres | 99.93 | 99.26 |
| Embodiment 36 | 9 g/acres | 98.15 | 99.32 |
| 5% fluorine lice sulfanilamide (SN) suspending agent (autogamy) | 22 g/acres | 64.95 | 69.23 |
| 10% flonicamid water dispersible granules | 45 g/acres | 65.76 | 68.78 |
| 10% bromine cyanogen insect amide suspending agent | 20 g/acres | 64.24 | 65.15 |
| 20% fipronil bisamide water dispersible granules | 22 g/acres | 68.47 | 67.11 |
| 200 grams per liter Rynaxypyr suspending agents | 5 g/acres | 66.31 | 68.24 |
| 15% Tolfenpyrad missible oil | 41 g/acres | 68.82 | 70.62 |
| 22% fluorine pyridine worm amine nitrile suspending agent | 24 g/acres | 67.29 | 69.83 |
As can be seen from Table 7, fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile are composite to be better than contrasting medicament afterwards to the Laphygma exigua Hubner control efficiency, lasting period is long, the test scope of medication in to crop safety.
Embodiment 37～56 suspending agents
Fluorine lice sulfanilamide (SN), active ingredient B, dispersant, wetting agent, defoamer, thickener, antifreeze are mixed through high speed shear, add former medicine, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, deionized water is supplied surplus, make fluorine lice sulfanilamide (SN) active ingredient B suspending agent product, active ingredient B comprises wherein a kind of of flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile.
Concrete prescription sees Table 8.
Table 8 embodiment 37～56 each component and weight portions
Flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile exchange in will showing, and can make novel formulation.
Table 9 fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile and the control eggplant thrips test of pesticide effectiveness that is mixed thereof
| Treatment agent | The preparation dosage | 3 days preventive effects (%) behind the medicine | 14 days preventive effects (%) behind the medicine |
| Embodiment 37 | 7 g/acres | 98.56 | 98.59 |
| Embodiment 38 | 6 g/acres | 99.51 | 99.47 |
| Embodiment 41 | 6 g/acres | 98.38 | 99.38 |
| Embodiment 42 | 5 g/acres | 99.24 | 98.16 |
| Embodiment 45 | 6 g/acres | 98.75 | 99.24 |
| Embodiment 46 | 4 g/acres | 97.82 | 98.12 |
| Embodiment 49 | 10 g/acres | 98.16 | 99.03 |
| Embodiment 50 | 3 g/acres | 99.01 | 99.29 |
| Embodiment 53 | 8 g/acres | 99.52 | 98.18 |
| Embodiment 55 | 20 g/acres | 98.38 | 98.56 |
| 5% fluorine lice sulfanilamide (SN) suspending agent (autogamy) | 15 g/acres | 65.51 | 67.02 |
| 10% flonicamid water dispersible granules | 45 g/acres | 64.19 | 68.55 |
| 10% bromine cyanogen insect amide suspending agent | 20 g/acres | 66.35 | 67.47 |
| 20% fipronil bisamide water dispersible granules | 22 g/acres | 65.27 | 64.94 |
| 200 grams per liter Rynaxypyr suspending agents | 8 g/acres | 66.48 | 68.53 |
| 15% Tolfenpyrad missible oil | 41 g/acres | 67.86 | 70.38 |
| 22% fluorine pyridine worm amine nitrile suspending agent | 24 g/acres | 65.64 | 71.06 |
As can be seen from Table 9, fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile are composite to be better than contrasting medicament afterwards to eggplant thrips control efficiency, lasting period is long, the test scope of medication in to crop safety.
Table 10 fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile and the control paddy rice rice leaf roller test of pesticide effectiveness that is mixed thereof
| Treatment agent | The preparation dosage | 3 days preventive effects (%) behind the medicine | 14 days preventive effects (%) behind the medicine |
| Embodiment 39 | 6 g/acres | 99.31 | 99.25 |
| Embodiment 40 | 5 g/acres | 98.17 | 98.14 |
| Embodiment 43 | 4 g/acres | 97.95 | 98.86 |
| Embodiment 44 | 8 g/acres | 98.26 | 98.37 |
| Embodiment 47 | 6 g/acres | 99.37 | 99.89 |
| Embodiment 48 | 5 g/acres | 98.29 | 98.15 |
| Embodiment 51 | 3 g/acres | 99.06 | 99.32 |
| Embodiment 52 | 4 g/acres | 99.52 | 99.18 |
| Embodiment 54 | 8 g/acres | 98.35 | 98.64 |
| Embodiment 56 | 5 g/acres | 98.34 | 98.47 |
| 5% fluorine lice sulfanilamide (SN) suspending agent (autogamy) | 20 g/acres | 68.96 | 67.12 |
| 10% flonicamid water dispersible granules | 45 g/acres | 69.25 | 65.36 |
| 10% bromine cyanogen insect amide suspending agent | 22 g/acres | 65.41 | 70.59 |
| 20% fipronil bisamide water dispersible granules | 27 g/acres | 64.72 | 71.13 |
| 200 grams per liter Rynaxypyr suspending agents | 6 g/acres | 65.59 | 70.84 |
| 15% Tolfenpyrad missible oil | 40 g/acres | 66.67 | 64.73 |
| 22% fluorine pyridine worm amine nitrile suspending agent | 25 g/acres | 64.21 | 67.52 |
As can be seen from Table 10, fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile are composite to be better than contrasting medicament afterwards to paddy rice rice leaf roller control efficiency, lasting period is long, the test scope of medication in to crop safety.
Embodiment 57～62 suspension emulsions
Active ingredient B, solvent, emulsifier, dispersant are added together, make and be dissolved into even oil phase; Fluorine lice sulfanilamide (SN), water, antifreeze, defoamer etc. are mixed, become the homogeneous water; Under high-speed stirred, water is added oil phase or oil phase is added water, make fluorine lice sulfanilamide (SN) active ingredient B suspension emulsion product behind the good dispersion, active ingredient B comprises wherein a kind of of flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile.
Concrete prescription sees Table 11.
Table 11 embodiment 57～62 each component and weight portions
Flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile exchange in will showing, and can make novel formulation.
Table 12 fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile and the control rape flea beetle test of pesticide effectiveness that is mixed thereof
| Treatment agent | The preparation dosage | 3 days preventive effects (%) behind the medicine | 14 days preventive effects (%) behind the medicine |
| Embodiment 57 | 6 g/acres | 99.12 | 98.75 |
| Embodiment 58 | 10 g/acres | 97.57 | 98.24 |
| Embodiment 59 | 4 g/acres | 99.31 | 99.48 |
| Embodiment 60 | 3 g/acres | 99.23 | 99.61 |
| Embodiment 61 | 6 g/acres | 99.38 | 99.26 |
| Embodiment 62 | 7 g/acres | 98.79 | 99.57 |
| 5% fluorine lice sulfanilamide (SN) suspending agent (autogamy) | 17 g/acres | 65.64 | 69.82 |
| 10% flonicamid water dispersible granules | 40 g/acres | 66.45 | 68.73 |
| 10% bromine cyanogen insect amide suspending agent | 25 g/acres | 68.24 | 68.58 |
| 20% fipronil bisamide water dispersible granules | 25 g/acres | 66.16 | 70.36 |
| 200 grams per liter Rynaxypyr suspending agents | 5 g/acres | 65.42 | 69.53 |
| 15% Tolfenpyrad missible oil | 45 g/acres | 66.28 | 68.64 |
| 22% fluorine pyridine worm amine nitrile suspending agent | 28 g/acres | 64.57 | 69.17 |
As can be seen from Table 12, fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile are composite to be better than contrasting medicament afterwards to rape flea beetle control efficiency, lasting period is long, the test scope of medication in to crop safety.
Embodiment 63～66 aqueous emulsions
Fluorine lice sulfanilamide (SN), active ingredient B, solvent and emulsifier are added together, make and be dissolved into even oil phase; Water, antifreeze, defoamer etc. are mixed, become the homogeneous water; Under high-speed stirred, water is added oil phase or oil phase is added water, make fluorine lice sulfanilamide (SN) flonicamid aqueous emulsion product behind the good dispersion, active ingredient B comprises wherein a kind of of flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile.
Concrete prescription sees Table 13.
Table 9 example 63～66 each component and content
Tolfenpyrad replaces with flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, fluorine pyridine worm amine nitrile and can make novel formulation in will showing.
Table 14 fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile and the control Chinese cabbage diamond-back moth test of pesticide effectiveness that is mixed thereof
| Treatment agent | The preparation dosage | 3 days preventive effects (%) behind the medicine | 14 days preventive effects (%) behind the medicine |
| Embodiment 63 | 5 g/acres | 97.58 | 98.04 |
| Embodiment 64 | 7 g/acres | 98.43 | 99.26 |
| Embodiment 65 | 6 g/acres | 99.15 | 99.73 |
| Embodiment 66 | 6 g/acres | 98.27 | 98.89 |
| 5% fluorine lice sulfanilamide (SN) suspending agent (autogamy) | 13 g/acres | 64.72 | 68.31 |
| 10% flonicamid water dispersible granules | 42 g/acres | 65.46 | 69.17 |
| 10% bromine cyanogen insect amide suspending agent | 28 g/acres | 64.84 | 70.28 |
| 20% fipronil bisamide water dispersible granules | 20 g/acres | 66.39 | 68.54 |
| 200 grams per liter Rynaxypyr suspending agents | 10 g/acres | 67.15 | 70.37 |
| 15% Tolfenpyrad missible oil | 50 g/acres | 65.83 | 67.21 |
| 22% fluorine pyridine worm amine nitrile suspending agent | 25 g/acres | 66.58 | 69.42 |
As can be seen from Table 14, fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile are composite to be better than contrasting medicament afterwards to Chinese cabbage diamond-back moth control efficiency, lasting period is long, the test scope of medication in to crop safety.
Embodiment 66～71 microcapsule suspending agents
The macromolecule cyst material is added the PH conditioning agent be heated to uniform temperature, obtain thick liquid, then thin up, form stable prepolymer solution, with fluorine lice sulfanilamide (SN), active ingredient B is dissolved in the organic solvent, be added to again in the prepolymer solution, add emulsifier, surfactant, and fully shear agitation is dispersed into superfine microgranular, add the PH conditioning agent again, and heat up, the catalysis polycondensation forms the microcapsules of firm difficult infiltration, make micro-capsule suspension of the present invention, active ingredient B comprises flonicamid, the bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, wherein a kind of of fluorine pyridine worm amine nitrile.
Concrete prescription sees Table 15.
Table 15 example 66～71 each component and content
Tolfenpyrad, fluorine pyridine worm amine nitrile replace with flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr and can make novel formulation in will showing.
Table 16 fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile and be mixed and prevent and treat the rice hoppers test of pesticide effectiveness
| Treatment agent | The preparation dosage | 3 days preventive effects (%) behind the medicine | 14 days preventive effects (%) behind the medicine |
| Embodiment 67 | 10 g/acres | 98.43 | 99.27 |
| Embodiment 68 | 5 g/acres | 99.16 | 98.95 |
| Embodiment 69 | 11 g/acres | 97.39 | 98.21 |
| Embodiment 70 | 4 g/acres | 98.84 | 99.19 |
| 5% fluorine lice sulfanilamide (SN) suspending agent (autogamy) | 15 g/acres | 68.23 | 70.42 |
| 10% flonicamid water dispersible granules | 40 g/acres | 65.45 | 68.36 |
| 10% bromine cyanogen insect amide suspending agent | 25 g/acres | 64.78 | 69.84 |
| 20% fipronil bisamide water dispersible granules | 15 g/acres | 66.17 | 69.23 |
| 200 grams per liter Rynaxypyr suspending agents | 8 g/acres | 68.62 | 69.51 |
| 15% Tolfenpyrad missible oil | 45 g/acres | 70.21 | 65.47 |
| 22% fluorine pyridine worm amine nitrile suspending agent | 30 g/acres | 65.36 | 68.79 |
As can be seen from Table 16, fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile are composite to be better than contrasting medicament afterwards to the rice hoppers control efficiency, lasting period is long, is testing scope of medication to crop safety.
Embodiment 72～77 microcapsule suspending agents-suspending agent
Adopt interfacial polymerization, active ingredient B, macromolecule cyst material, organic solvent in the above-mentioned prescription are mixed, make and be dissolved into even oil phase, under shearing condition, join oil phase in the aqueous phase solution that contains emulsifier, pH adjusting agent, bi-material reacts at oil-water interfaces, form the macromolecule cyst wall around the drop that contains chemical substance, make active ingredient B micro-capsule suspension.With surfactant, defoamer, thickener, antifreeze mixes through high speed shear, add the former medicine of fluorine lice sulfanilamide (SN), ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make fluorine lice sulfanilamide (SN) suspending agent, then will be dissolved in fluorine lice sulfanilamide (SN) suspending agent stable in the water joins in the aqueous phase solution of active ingredient B micro-capsule suspension, make the finely disseminated microcapsule suspension of the present composition-suspending agent product, active ingredient B comprises flonicamid, the bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, wherein a kind of of fluorine pyridine worm amine nitrile.
Concrete prescription sees Table 17.
Table 17 embodiment 72～77 each component and weight portions
Flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr replace with Tolfenpyrad in will showing, fluorine pyridine worm amine nitrile can make novel formulation.
Table 18 fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile and the control apple aphid test of pesticide effectiveness that is mixed thereof
| Treatment agent | Extension rate | 3 days preventive effects (%) behind the medicine | 14 days preventive effects (%) behind the medicine |
| Embodiment 71 | 6500 times | 98.14 | 99.25 |
| Embodiment 72 | 7000 times | 98.76 | 99.01 |
| Embodiment 73 | 6000 times | 97.59 | 98.38 |
| Embodiment 74 | 6000 times | 99.21 | 99.46 |
| 5% fluorine lice sulfanilamide (SN) suspending agent (autogamy) | 3000 times | 65.37 | 69.84 |
| 10% flonicamid water dispersible granules | 3000 times | 64.25 | 70.57 |
| 10% bromine cyanogen insect amide suspending agent | 2500 times | 64.72 | 68.69 |
| 20% fipronil bisamide water dispersible granules | 4000 times | 65.13 | 69.78 |
| 200 grams per liter Rynaxypyr suspending agents | 5000 times | 66.49 | 70.23 |
| 15% Tolfenpyrad missible oil | 2000 times | 65.68 | 68.45 |
| 22% fluorine pyridine worm amine nitrile suspending agent | 2500 times | 64.34 | 67.66 |
As can be seen from Table 23, fluorine lice sulfanilamide (SN) and flonicamid, bromine cyanogen insect amide, fipronil bisamide, Rynaxypyr, Tolfenpyrad, fluorine pyridine worm amine nitrile are composite to be better than contrasting medicament afterwards to the apple aphid control efficiency, lasting period is long, the test scope of medication in to crop safety.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.First by Toxicity Determination, the co-toxicity coefficient (CTC) after clear and definite two kinds of medicaments are composite by a certain percentage, CTC＜80 are antagonism, and 80≤CTC≤120 are summation action, and CTC＞120 are synergistic effect, on this basis, carry out field trial again.
Test method: respectively the mother liquor of each mixed agent is diluted to five series concentration during test, places respectively beaker for subsequent use.Adopt and to soak first the method that connects worm behind the leaf, the blade of the same size that does not contact any medicament soaked in the liquid that configures behind the 5s take out, naturally dry, put into insect box, then connect for the examination larva, under 25 ℃ of conditions, raise, every processing repeats for 3 times, every to repeat used examination borer population be 50, establishes simultaneously blank, checks dead borer population in 72h, calculate lethality and corrected mortality, try to achieve virulence regression equation and calculate LC
50Value.If the contrast lethality then is considered as invalid test greater than 10%.Computing formula is as follows:
The insect corrected mortality is converted into probit value (y), and concentration for the treatment of (μ g/ml) converts logarithm value (x) to, draws virulence regression equation with method of least squares, and calculates thus the value of every kind of medicament.Calculate co-toxicity coefficient CTC according to the abundant equation of Sun Yun.Computing formula following (take fluorine lice sulfanilamide (SN) as the standard medicament, its toxicity index is 100):
TI * the P of the theoretical toxicity index (TTI) of M=fluorine lice sulfanilamide (SN)
Fluorine lice sulfanilamide (SN)TI * P of+effective active composition B
Effective active composition B
In the formula: M is the mixture of different proportionings
P
Effective active composition BBe effective active composition B shared ratio in composition
P
Fluorine lice sulfanilamide (SN)Be fluorine lice sulfanilamide (SN) shared ratio in composition
Annotate: active component B is selected from following any one compound: a kind of in flonicamid, bromine cyanogen insect amide, Rynaxypyr, fipronil bisamide, Tolfenpyrad, the fluorine pyridine worm amine nitrile.
Application Example two: for trying insect: apple aphid.
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective lethal concentration scope of determining fluorine lice sulfanilamide (SN), the former medicine of flonicamid and the two different proportioning mixture through preliminary experiment.
Toxicity test result one
The different proportionings from flonicamid of table 19 fluorine lice sulfanilamide (SN) are to the toxicity test of apple aphid
As shown in Table 19, the proportioning of the composite control apple aphid of fluorine lice sulfanilamide (SN) and flonicamid was at 70: 1 to 1: 70 o'clock, co-toxicity coefficient is all greater than 120, illustrating that both were mixed in the scope at 70: 1 to 1: 70 all shows synergistic effect, especially when the proportioning of fluorine lice sulfanilamide (SN) and flonicamid during at 10: 1 to 1: 20, synergistic effect is more obviously outstanding, wherein co-toxicity coefficient is maximum when fluorine lice sulfanilamide (SN) and flonicamid weight ratio are 1: 3, synergistic effect is the most obvious, find simultaneously, fluorine lice sulfanilamide (SN) and flonicamid proportioning were at 10: 1,9: 1,8: 1,7: 1,6: 1,5: 1,4: 1,3: 1,2: 1,1: 1,1: 2,1: 3,1: 4,1: 5,1: 6,1: 7,1: 8,1: 9,1: 10,1: 11,1: 12,1: 13,1: 14,1: 15,1: 16,1: 17,1: 18,1: 19,1: 20 o'clock composite to fleahopper, mythimna separata, cotton bollworm, potato tuberworm, beet armyworm, diamond-back moth, peach fruit borer, the apple olethreutid, striped rice borer, paddy stem borer, rice leaf roller, cabbage caterpillar, lima bean pod borer, rice fulgorid, flea beetle, thrips, aleyrodid, prodenia litura also has good synergistic effect, and co-toxicity coefficient is all greater than 200.
Application Example three: for trying insect: rice hoppers.
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective lethal concentration scope of determining fluorine lice sulfanilamide (SN), the former medicine of bromine cyanogen insect amide and the two different proportioning mixture through preliminary experiment.
Toxicity test result two
The different proportionings from the bromine cyanogen insect amide of table 20 fluorine lice sulfanilamide (SN) are to the toxicity test of rice hoppers
As shown in Table 20, the composite proportioning of rice hoppers of preventing and treating of fluorine lice sulfanilamide (SN) and bromine cyanogen insect amide was at 70: 1 to 1: 70 o'clock, co-toxicity coefficient is all greater than 120, illustrating that both were mixed in the scope at 70: 1 to 1: 70 all shows synergistic effect, especially when fluorine lice sulfanilamide (SN) and bromine cyanogen insect amide got proportioning at 10: 1 to 1: 20, synergistic effect was more obviously outstanding, tests through the applicant, co-toxicity coefficient is maximum when fluorine lice sulfanilamide (SN) and bromine cyanogen insect amide weight ratio are 1: 3, and synergistic effect is the most obvious.Find simultaneously, fluorine lice sulfanilamide (SN) and bromine cyanogen insect amide proportioning were at 10: 1,9: 1,8: 1,7: 1,6: 1,5: 1,4: 1,3: 1,2: 1,1: 1,1: 2,1: 3,1: 4,1: 6,1: 7,1: 8,1: 9,1: 10,1: 11,1: 12,1: 13,1: 14,1: 16,1: 17,1: 18,1: 19,1: 20 o'clock composite to fleahopper, mythimna separata, cotton bollworm, potato tuberworm, beet armyworm, diamond-back moth, peach fruit borer, the apple olethreutid, striped rice borer, paddy stem borer, rice leaf roller, cabbage caterpillar, lima bean pod borer, rice fulgorid, aphid, flea beetle, thrips, aleyrodid, prodenia litura also has good synergistic effect, and co-toxicity coefficient is all greater than 200.
Application Example four: for trying insect: the Chinese cabbage diamond-back moth.
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective lethal concentration scope of determining fluorine lice sulfanilamide (SN), the former medicine of fipronil bisamide and the two different proportioning mixture through preliminary experiment.
Toxicity test result three
The different proportionings from fipronil bisamide of table 21 fluorine lice sulfanilamide (SN) are to the toxicity test of Chinese cabbage diamond-back moth
As shown in Table 21, the proportioning of the composite control of fluorine lice sulfanilamide (SN) and fipronil bisamide Chinese cabbage diamond-back moth was at 70: 1 to 1: 70 o'clock, co-toxicity coefficient is all greater than 120, illustrating that both were mixed in the scope at 70: 1 to 1: 70 all shows synergistic effect, especially when fluorine lice sulfanilamide (SN) and fipronil bisamide got proportioning at 10: 1 to 1: 20, synergistic effect was more obviously outstanding, tests through the applicant, co-toxicity coefficient is maximum when fluorine lice sulfanilamide (SN) and fipronil bisamide weight ratio are 1: 3, and synergistic effect is the most obvious.Find simultaneously, fluorine lice sulfanilamide (SN) and fipronil bisamide proportioning were at 10: 1,9: 1,8: 1,7: 1,6: 1,5: 1,4: 1,3: 1,2: 1,1: 1,1: 2,1: 3,1: 4,1: 5,1: 6,1: 7,1: 8,1: 9,1: 10,1: 11,1: 12,1: 13,1: 14,1: 15,1: 16,1: 17,1: 18,1: 19,1: 20 o'clock composite to fleahopper, mythimna separata, cotton bollworm, potato tuberworm, beet armyworm, the apple olethreutid, striped rice borer, paddy stem borer, rice leaf roller, cabbage caterpillar, lima bean pod borer, rice fulgorid, aphid, flea beetle, thrips, aleyrodid, prodenia litura also has good synergistic effect, and co-toxicity coefficient is all greater than 200.
Application Example five: for trying insect: the paddy rice rice leaf roller.
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: determine that through preliminary experiment fluorine lice sulfanilamide (SN) is in effective lethal concentration scope of the former medicine of Rynaxypyr and the two different proportioning mixture.
Toxicity test result four
The different proportionings from Rynaxypyr of table 22 fluorine lice sulfanilamide (SN) are to the toxicity test of paddy rice rice leaf roller
As shown in Table 22, the proportioning of the composite control of fluorine lice sulfanilamide (SN) and Rynaxypyr paddy rice rice leaf roller was at 70: 1 to 1: 70 o'clock, co-toxicity coefficient is all greater than 120, illustrating that both were mixed in the scope at 70: 1 to 1: 70 all shows synergistic effect, especially when fluorine lice sulfanilamide (SN) and Rynaxypyr get proportioning at 10: 1 to 1: 10, synergistic effect is more obviously outstanding, test through the applicant, co-toxicity coefficient is maximum when fluorine lice sulfanilamide (SN) and Rynaxypyr weight ratio are 1: 2, and synergistic effect is the most obvious.Find simultaneously, fluorine lice sulfanilamide (SN) and Rynaxypyr proportioning are composite at 10: 1,9: 1,8: 1,7: 1,6: 1,5: 1,4: 1,3: 1,2: 1,1: 1,1: 2,1: 3,1: 4,1: 5,1: 6,1: 7,1: 8,1: 9,1: 10 o'clock also to have good synergistic effect to fleahopper, cotton bollworm, potato tuberworm, beet armyworm, diamond-back moth, peach fruit borer, apple olethreutid, striped rice borer, paddy stem borer, cabbage caterpillar, lima bean pod borer, rice fulgorid, aphid, flea beetle, thrips, aleyrodid, prodenia litura, and co-toxicity coefficient is all greater than 200.
Application Example five: for trying insect: the eggplant thrips.
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective lethal concentration scope of determining fluorine lice sulfanilamide (SN) and the former medicine of Tolfenpyrad and the two different proportioning mixture through preliminary experiment.
Toxicity test result four
The different proportionings from Tolfenpyrad of table 23 fluorine lice sulfanilamide (SN) are to the toxicity test of eggplant thrips
As shown in Table 23, the proportioning of the composite control eggplant of fluorine lice sulfanilamide (SN) and Tolfenpyrad thrips was at 70: 1 to 1: 70 o'clock, co-toxicity coefficient is all greater than 120, illustrating that both were mixed in the scope at 70: 1 to 1: 70 all shows synergistic effect, especially when fluorine lice sulfanilamide (SN) and Tolfenpyrad got proportioning at 10: 1 to 1: 30, synergistic effect was more obviously outstanding, tests through the applicant, co-toxicity coefficient is maximum when fluorine lice sulfanilamide (SN) and Tolfenpyrad weight ratio are 1: 6, and synergistic effect is the most obvious.Find simultaneously, fluorine lice sulfanilamide (SN) and Tolfenpyrad proportioning were at 10: 1,9: 1,8: 1,7: 1,6: 1,5: 1,4: 1,3: 1,2: 1,1: 1,1: 2,1: 3,1: 4,1: 5,1: 6,1: 7,1: 8,1: 9,1: 10,1: 11,1: 12,1: 13,1: 14,1: 15,1: 16,1: 17,1: 18,1: 19,1: 20,1: 25,1: 30 o'clock composite to fleahopper, mythimna separata, cotton bollworm, potato tuberworm, beet armyworm, diamond-back moth, peach fruit borer, the apple olethreutid, striped rice borer, paddy stem borer, rice leaf roller, cabbage caterpillar, lima bean pod borer, rice fulgorid, aphid, prodenia litura also has good synergistic effect, and co-toxicity coefficient is all greater than 200.
Application Example five: for trying insect: the cotton aleyrodid.
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective lethal concentration scope of determining fluorine lice sulfanilamide (SN) and the fluorine pyridine worm former medicine of amine nitrile and the two different proportioning mixture through preliminary experiment.
Toxicity test result four
Table 24 fluorine lice sulfanilamide (SN) and the toxicity test of the different proportionings of fluorine pyridine worm amine nitrile to the cotton aleyrodid
As shown in Table 24, the proportioning of the composite control of fluorine lice sulfanilamide (SN) and fluorine pyridine worm amine nitrile cotton aleyrodid was at 70: 1 to 1: 70 o'clock, co-toxicity coefficient is all greater than 120, illustrating that both were mixed in the scope at 70: 1 to 1: 70 all shows synergistic effect, especially when fluorine lice sulfanilamide (SN) and fluorine pyridine worm amine nitrile got proportioning at 10: 1 to 1: 20, synergistic effect was more obviously outstanding, tests through the applicant, co-toxicity coefficient is maximum when fluorine lice sulfanilamide (SN) and fluorine pyridine worm amine nitrile weight ratio are 1: 6, and synergistic effect is the most obvious.Find simultaneously, fluorine lice sulfanilamide (SN) and fluorine pyridine worm amine nitrile proportioning were at 10: 1,9: 1,8: 1,7: 1,6: 1,5: 1,4: 1,3: 1,2: 1,1: 1,1: 2,1: 3,1: 4,1: 5,1: 6,1: 7,1: 8,1: 9,1: 10,1: 11,1: 12,1: 13,1: 14,1: 15,1: 16,1: 17,1: 18,1: 19,1: 20 o'clock composite to fleahopper, mythimna separata, cotton bollworm, beet armyworm, diamond-back moth, peach fruit borer, the apple olethreutid, striped rice borer, paddy stem borer, rice leaf roller, cabbage caterpillar, lima bean pod borer, rice fulgorid, aphid, flea beetle, thrips, prodenia litura also has good synergistic effect, and co-toxicity coefficient is all greater than 200.
Claims (6)
1. the Pesticidal combination of a fluorine-containing lice sulfanilamide (SN), it is characterized in that: contain active components A and active component B, the weight ratio of active components A and active component B is 1: 70～70: 1, described active components A is selected from fluorine lice sulfanilamide (SN), and active component B is selected from a kind of in flonicamid, bromine cyanogen insect amide, Rynaxypyr, fipronil bisamide, Tolfenpyrad, the fluorine pyridine worm amine nitrile.
2. the Pesticidal combination of fluorine-containing lice sulfanilamide (SN) according to claim 1, it is characterized in that: the weight ratio of active components A and active component B is 1: 50～30: 1.
3. the Pesticidal combination of fluorine-containing lice sulfanilamide (SN) according to claim 2, its feature exists
In: the weight ratio of fluorine lice sulfanilamide (SN) and flonicamid is 10: 1～1: 20;
The weight ratio of fluorine lice sulfanilamide (SN) and bromine cyanogen insect amide is 10: 1～1: 20;
The weight ratio of fluorine lice sulfanilamide (SN) and Rynaxypyr is 10: 1～1: 10;
The weight ratio of fluorine lice sulfanilamide (SN) and fipronil bisamide is 10: 1～1: 20;
The weight ratio of fluorine lice sulfanilamide (SN) and Tolfenpyrad is 10: 1～1: 30;
The weight ratio of fluorine lice sulfanilamide (SN) and fluorine pyridine worm amine nitrile is 10: 1～1: 30.
4. the Pesticidal combination of each described fluorine-containing lice sulfanilamide (SN) in 3 according to claim 1, it is characterized in that: composition is made wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspending agent-suspending agent.
5. the Pesticidal combination of fluorine-containing lice sulfanilamide (SN) according to claim 4 is used for the purposes of control crop pest.
6. purposes according to claim 5, it is characterized in that described insect comprises: fleahopper, mythimna separata, cotton bollworm, potato tuberworm, beet armyworm, diamond-back moth, peach fruit borer, apple olethreutid, striped rice borer, paddy stem borer, rice leaf roller, cabbage caterpillar, lima bean pod borer, rice fulgorid, aphid, flea beetle, thrips, aleyrodid, prodenia litura.
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| CN201210116351.XA CN103371164B (en) | 2012-04-19 | 2012-04-19 | A kind of Pesticidal combination of fluorine-containing louse sulfanilamide |
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| CN103371164B (en) | 2016-08-17 |
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