CN103340959A - Oldenlandia diffusa essence, as well as preparation method and pharmic application thereof - Google Patents
Oldenlandia diffusa essence, as well as preparation method and pharmic application thereof Download PDFInfo
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- CN103340959A CN103340959A CN2013102880497A CN201310288049A CN103340959A CN 103340959 A CN103340959 A CN 103340959A CN 2013102880497 A CN2013102880497 A CN 2013102880497A CN 201310288049 A CN201310288049 A CN 201310288049A CN 103340959 A CN103340959 A CN 103340959A
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- essence
- herba hedyotidis
- hedyotidis diffusae
- oldenlandia diffusa
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Abstract
The invention discloses an oldenlandia diffusa essence, as well as a preparation method and a pharmic application thereof. The traditional Chinese medicine essence is a dry powdery drug extracted from oldenlandia diffusa. The extraction technique of the essence comprises the steps of: weighing the oldenlandia diffusa raw material, washing the raw material and drying the raw material for later use, crushing the spare oldenlandia diffusa and adding water to form crushed paste, heating the crushed paste to 100 DEG C and decocting the crushed paste for 30 minutes, then filtering the paste to obtain a filtered fluid, cooling the filtered fluid, adding protease, cellulose and diastase, and stirring the mixture for certain time, using edible acetic acid to regulate the pH value to be 4.0, standing the fluid for one day, and drying the stood fluid to obtain a dry powdery traditional Chinese essence for treating tongue diseases. The traditional Chinese essence provided by the invention can effectively improve the immunity of tongue cells, promote formation of antibody, and has a remarkable antiphlogistic effect. Besides, the preparation method of the oldenlandia diffusa essence disclosed by the invention is simple in steps, convenient to implement, high in extraction rate, and suitable for large-scale batch production.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine and method for making thereof, relate in particular to a kind of Herba Hedyotidis Diffusae essence and method for making and pharmaceutical applications.
Background technology
The tongue disease comprises that mainly tongue festers, tongue is sent out stiff etc.Wherein to fester be because heart-fire is big, fire of moxibustion is very heavy or snacking has been stung tongue and cause to tongue mostly.The performance of its symptom is looked the degree of being in a bad way and is divided into light-duty, heavy type and herpesvirus type, brings no small trouble and misery in the aspect on the feed usually for the patient.
Tongue sends out also to be a Chinese medicine performance of tongue disease stiff, also is the body void slow blood flow of getting angry, and blood viscosity increases, and microcirculation changes, due to local blood supply insufficiency or the cerebral blood supply insufficiency.
Summary of the invention
Demand in view of above-mentioned prior art exists the objective of the invention is to propose a kind of Herba Hedyotidis Diffusae essence and pharmaceutical applications thereof, and proposes the higher Chinese medicine essence extraction process of a kind of effective ingredient extraction.
One of above-mentioned purpose of the present invention Herba Hedyotidis Diffusae essence, its technical scheme that is achieved is: described Chinese medicine essence is for extracting the dry powder attitude medicine from the Agkistrodon SHECAO.
The method for making of two Herba Hedyotidis Diffusae essences of above-mentioned purpose of the present invention, its technical scheme that is achieved comprises operating procedure: I, weighing Herba Hedyotidis Diffusae, in stainless steel tank, to carry out routine and clean, taking-up is dried standby; II, standby Herba Hedyotidis Diffusae is pulverized, smashing fineness reaches 200 orders, and the water that adds 10 times of raw material of Chinese medicine gross masses again mixes, and produces to pulverize mud; III, will pulverize mud and put into stainless-steel pan, be heated to 100 ℃, decoct 30 minutes, then add the filtration cloth bag at the blowing valve port, and open baiting valve then and filter, obtain filtrate; IV, in aseptic dust free room, filtrate poured in the stainless-steel pan with agitating device stir, be cooled to 18 ℃, add raw material of Chinese medicine gross weight each protease, cellulase and diastase of 0.3% again, under the condition of rotating speed 30 times/minute, stirred 2 hours, and with tablet vinegar acid for adjusting pH value 4.0, left standstill 24 hours; V, in aseptic temperature control workshop, the liquid that leaves standstill put into the centrifuge dehydration after, the precipitate that produces is put into electric heating aerator setting constant temperature carried out drying 8 hours for 45 ℃, obtain the Herba Hedyotidis Diffusae essence of dry powder attitude, the weight of this Chinese medicine essence is 6% of Herba Hedyotidis Diffusae raw material gross weight.
The pharmaceutical applications of three Herba Hedyotidis Diffusae essences of above-mentioned purpose of the present invention is characterized in that: described essence is used for the treatment of the tongue disease.
The technical scheme of Chinese medicine essence of the present invention and extraction process thereof, its outstanding effect is: this Chinese medicine essence can effectively improve the immunity of tongue cell, increase antibody and form, and the antiinflammatory effect is remarkable.Extraction process step of the present invention is simple in addition, and it is convenient to implement, and extraction is higher, and being suitable in batches, scale produces.
The specific embodiment
Because present present situation relatively poor to tongue disease curative effect, that recur often, the concentrated research of this case creator Chinese medicine medical knowledge can effectively be prevented and treated Chinese herbal medicine material, the test of tongue disease through exploring, and finds technical solution preferably finally.
After deliberation, the present invention proposes a kind of Herba Hedyotidis Diffusae essence, and it is for extracting the dry powder attitude medicine from the Agkistrodon SHECAO.
From pharmacology: cool in nature, the sweet in the mouth of Herba Hedyotidis Diffusae has the effect of heat-clearing and toxic substances removing.Cure mainly enterodynia, furuncle toxic swelling, damp and hot jaundice, promoting blood circulation and stopping pain.Herba Hedyotidis Diffusae has the effect that strengthens humoral immunization and cellular immunization.Strengthen reticuloendothelial system and leukocytic phagocytic function, can increase antibody and form, and have stronger antiinflammation.
From the method for making embodiments of the invention, it comprises following operating procedure.
I, weighing Herba Hedyotidis Diffusae 10kg carry out routine and clean in stainless steel tank, taking-up is dried standby; II, standby Herba Hedyotidis Diffusae is pulverized, smashing fineness reaches the 150-300 order, and the water that adds 100kg again mixes, and produces to pulverize mud; III, will pulverize mud and put into stainless-steel pan, be heated to 100 ℃, decoct 30 minutes, then add the filtration cloth bag at the blowing valve port, and open baiting valve then and filter, obtain filtrate; IV, in aseptic dust free room, filtrate poured in the stainless-steel pan with agitating device stir, be cooled to 18 ℃, add the protease of 0.03kg, the cellulase of 0.03kg and the diastase of 0.03kg again, under the condition of rotating speed 30 times/minute, stirred 2 hours, and with tablet vinegar acid for adjusting pH value 4.0, left standstill 24 hours; V, in aseptic temperature control workshop, the liquid that leaves standstill put into the centrifuge dehydration after, the precipitate that produces is put into the electric heating aerator sets constant temperature and carried out drying 8 hours for 45 ℃, obtain the Herba Hedyotidis Diffusae essence of 0.6kg dry powder attitude.
The embodiment of the invention is intended to be convenient to understand innovation essence of the present invention; but do not limit protection scope of the present invention; all simple modification or equivalence are replaced, or utilize this finished product powder processing and fabricating capsule, pill, injection etc., all should be contained among the scope of the present invention.
Medical record is introduced: Herba Hedyotidis Diffusae of the present invention is extracted element through development for many years, and its pharmaceutical applications can be treated the tongue disease, and the input clinical trial is evident in efficacy.
Mrs city in certain, Xu Qin, over fifty years old now.Serious oral ulcer before this, speck one by one on red tongue, the tongue has formed two bigger specks, deadlock and firmly at tongue at last.Patient talk at ordinary times, eat all effected and pain very.Through seeking medical advice everywhere, it is invalid that each municipal hospital all seeks medical advice, and back expert consultation is reached the medical science conclusion that need slice off the mashed tongue of part.The patient can't accept, by this city Disease Control and Prevention Center introduce take Herba Hedyotidis Diffusae essence of the present invention after, short several months tongue is namely cured voluntarily, no cicatrix.
This shows, the technical scheme of Herba Hedyotidis Diffusae essence of the present invention and extraction process thereof, its outstanding effect is: this Chinese medicine essence can effectively improve the immunity of tongue cell, increase antibody and form, and the antiinflammatory effect is remarkable.Extraction process step of the present invention is simple in addition, and it is convenient to implement, and extraction is higher, and being suitable in batches, scale produces.
Claims (3)
1. Herba Hedyotidis Diffusae essence is characterized in that: described Chinese medicine essence is for extracting the dry powder attitude medicine from the Agkistrodon SHECAO.
2. the extraction process of a Herba Hedyotidis Diffusae essence, its feature comprises operating procedure:
I, weighing Herba Hedyotidis Diffusae carry out routine and clean in stainless steel tank, taking-up is dried standby;
II, standby Herba Hedyotidis Diffusae is pulverized, smashing fineness reaches 200 orders, and the water that adds 10 times of raw material of Chinese medicine gross masses again mixes, and produces to pulverize mud;
III, will pulverize mud and put into stainless-steel pan, be heated to 100 ℃, decoct 30 minutes, then add the filtration cloth bag at the blowing valve port, and open baiting valve then and filter, obtain filtrate;
IV, in aseptic dust free room, filtrate poured in the stainless-steel pan with agitating device stir, be cooled to 18 ℃, add raw material of Chinese medicine gross weight each protease, cellulase and diastase of 0.3% again, under the condition of rotating speed 30 times/minute, stirred 2 hours, and with tablet vinegar acid for adjusting pH value 4.0, left standstill 24 hours;
V, in aseptic temperature control workshop, the liquid that leaves standstill put into the centrifuge dehydration after, the precipitate that produces is put into electric heating aerator setting constant temperature carried out drying 8 hours for 45 ℃, obtain the Herba Hedyotidis Diffusae essence of dry powder attitude, the weight of this Chinese medicine essence is 6% of Herba Hedyotidis Diffusae raw material gross weight.
3. the pharmaceutical applications of a Herba Hedyotidis Diffusae essence, it is characterized in that: described Herba Hedyotidis Diffusae essence is used for the treatment of the tongue disease.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013102880497A CN103340959A (en) | 2013-07-10 | 2013-07-10 | Oldenlandia diffusa essence, as well as preparation method and pharmic application thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013102880497A CN103340959A (en) | 2013-07-10 | 2013-07-10 | Oldenlandia diffusa essence, as well as preparation method and pharmic application thereof |
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| CN103340959A true CN103340959A (en) | 2013-10-09 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2013102880497A Pending CN103340959A (en) | 2013-07-10 | 2013-07-10 | Oldenlandia diffusa essence, as well as preparation method and pharmic application thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111494277A (en) * | 2020-04-28 | 2020-08-07 | 广州欧正化妆品技术研究院有限公司 | Acne removing factor, acne removing soft mask gel and preparation method thereof |
-
2013
- 2013-07-10 CN CN2013102880497A patent/CN103340959A/en active Pending
Non-Patent Citations (2)
| Title |
|---|
| 李云梅: "《多糖的提取分离及纯化研究》", 《中国民族民间医药》 * |
| 李春玲等: "《白花蛇舌草多糖的提取工艺研究》", 《中兽医医药杂志》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111494277A (en) * | 2020-04-28 | 2020-08-07 | 广州欧正化妆品技术研究院有限公司 | Acne removing factor, acne removing soft mask gel and preparation method thereof |
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| PB01 | Publication | ||
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20131009 |