CN103393748A - Traditional Chinese medicine essence for treating gout and extraction technology thereof - Google Patents
Traditional Chinese medicine essence for treating gout and extraction technology thereof Download PDFInfo
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- CN103393748A CN103393748A CN2013103486892A CN201310348689A CN103393748A CN 103393748 A CN103393748 A CN 103393748A CN 2013103486892 A CN2013103486892 A CN 2013103486892A CN 201310348689 A CN201310348689 A CN 201310348689A CN 103393748 A CN103393748 A CN 103393748A
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Abstract
The invention discloses a traditional Chinese medicine essence for treating gout and an extraction technology of the essence. The traditional Chinese medicine essence is extracted from the mixture of Chinese starjasmine stem, cynanchum paniculatum and sargent gloryvine. The extraction technology comprises the following steps of: weighing the raw materials according to a proportion, washing the weighed raw materials, drying the washed raw materials in the sun for later use, mixing and crushing the spare traditional Chinese medicine raw materials, adding water into the crushed mixture to obtain a slurry, heating the slurry to 100 DEG C for decoction for 60 minutes, filtering the decoction to obtain traditional Chinese medicine slurry, cooling the traditional Chinese medicine slurry, stirring the cooled traditional Chinese medicine slurry for certain time in the existence of an additive, regulating the pH of the resulting slurry to 5.0 by using alimentary acetic acid, causing the pH-regulated slurry to stand for 8-16 hours, and desiccating the stood liquid to obtain the traditional Chinese medicine essence for treating the gout in a dry powder state. After the traditional Chinese medicine essence disclosed by the invention is used, the reabsorption of lithic acid by kidney tubules is effectively inhibited without toxic effect and side effect and the excretion of uric acid can be accelerated so as to eliminate bruise, kill pain and eliminate the symptoms of the gout. In addition, the extraction technology disclosed by the invention is simple in technical steps, convenient to implement, high in extraction rate, and suitable for mass scale production.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine and method for making thereof, relate in particular to a kind of Chinese medicine essence and extraction process thereof that is used for the treatment of gout.
Background technology
Gout is a kind of metabolic disease, and along with people's living standard improves, physical labor intensity alleviates to some extent, makes patient with gout grow with each passing day.
The danger of gout, from its " disguise ", when people indulge in table delicacies delicacy, has but been ignored blood uric acid and has been raise gradually in vivo, causes acute gouty arthritis or urate nephropathy, even renal failure occur.Another danger of gout is from its repeatability, one day namely, a few days namely goes, and also has aggressive.Gout can cause health, and some organizes major injury, as destruction of joint, kidney injury, complicated with cardiovascular disease, hypertension etc., makes the state of an illness refractory that hardens the neck.
Summary of the invention
Demand in view of above-mentioned prior art exists, the objective of the invention is to propose a kind of Chinese medicine essence that achieves noticeable achievement for the treatment of gout, and propose the Chinese medicine essence extraction process that a kind of effective ingredient extraction is higher.
The Chinese medicine essence of one of above-mentioned purpose of the present invention treatment gout, its technical scheme that is achieved is: described Chinese medicine essence extracts the mixture from Caulis Trachelospermi, Radix Cynanchi Paniculati and Caulis Sargentodoxae, and described mixture component by weight is: Caulis Trachelospermi 20-50 part, Radix Cynanchi Paniculati 20-60 part, Caulis Sargentodoxae 30-60 part.
Further, in described mixture, each component is 1:1:1 by weight.
The extraction process of the Chinese medicine essence of two treatment gouts of above-mentioned purpose of the present invention, its technical scheme that is achieved comprises operating procedure: I, by the quality proportioning: Caulis Trachelospermi 20-50 part, Radix Cynanchi Paniculati 20-60 part, three kinds of raw material of Chinese medicine of Caulis Sargentodoxae 30-60 part weighing, in stainless steel tank, carry out routine and clean, taking-up is dried standby; II, by standby raw material of Chinese medicine co-grinding, smashing fineness reaches the 100-200 order, then adds the water of 10 times of raw material of Chinese medicine gross masses to mix, and produces slip; III, slip is put into to stainless-steel pan, be heated to 100 ℃, decocted 60 minutes, then put into Filter Press and obtain the herb liquid slurry; IV, indoor at bacteria-and dust-free, the herb liquid slurry is poured in the stainless-steel pan with agitating device and stirred, be cooled to 15-18 ℃, then add a certain amount of protease, cellulase and diastase, stirred 2 hours and used tablet vinegar acid for adjusting pH value 5.0, standing 8-16 hour; V, standing liquid is put into to centrifuge dehydration in aseptic temperature control workshop after, the precipitate that produces is put into to 45 ℃ of electric heating aerator setting constant temperature and carry out dry 4-7 hour, obtain the Chinese medicine essence of the treatment gout of dry powder state, the weight of this Chinese medicine essence is the 5-7% of three kinds of raw material of Chinese medicine gross weights.
Further, in the abovementioned steps IV, the protease addition is the 0.2-0.4% of three kinds of raw material of Chinese medicine gross weights.
Further, abovementioned steps IV cellulase addition is the 0.2-0.4% of three kinds of raw material of Chinese medicine gross weights.
Further, in the abovementioned steps IV, the diastase addition is the 0.15-0.25% of three kinds of raw material of Chinese medicine gross weights.
The technical scheme of Chinese medicine essence of the present invention and extraction process thereof, its outstanding effect is: this Chinese medicine essence has effectively suppressed the heavily absorption of renal tubules to uric acid under zero toxic and side effects, can accelerate urate excretion, thereby realizes disappearing the silt pain relieving, eliminates the gout symptom; Extraction process step of the present invention is simple in addition, and it is convenient to implement, and extraction is higher, is suitable for scale in batches and produces.
The specific embodiment
This case creator supports I am sent to gateway of a country pursuit of advanced studies thoughts on the painful of patient with gout and country, special concentrated Study of Traditional Chinese Medicine medical knowledge, through explore the treatment gout Chinese herbal medicine material, test, finally find technical solution preferably.
After deliberation, the present invention proposes a kind of Chinese medicine essence for the treatment of gout, and it extracts the mixture from Caulis Trachelospermi, Radix Cynanchi Paniculati and Caulis Sargentodoxae, and described mixture component by weight is: Caulis Trachelospermi 20-50 part, Radix Cynanchi Paniculati 20-60 part, Caulis Sargentodoxae 30-60 part.Preferred geometric ratio restructuring is joined.
From pharmacology: Caulis Trachelospermi has the disappear effect of pain of dispelling wind and removing obstruction in the collateral, removing heat from blood, is mainly used in clinically treatment rheumatoid arthritis, osteoarthritis, gouty arthritis etc.Caulis Trachelospermi is very effective to the degraded uric acid.
Radix Cynanchi Paniculati has promoting blood circulation by removing wind, the effect of detumescence of alleviating pain, and is mainly used in clinically rheumatoid arthritis, dry syndrome, gout, osteoarthritis etc.
Caulis Sargentodoxae has the effect of heat-clearing and toxic substances removing, promoting blood circulation by removing wind, is mainly used in clinically treatment acute and chronic gout, effectively quickly reducing swelling and alleviating pain.
Above three flavor Chinese medicines have suppressed the heavily absorption of renal tubules to uric acid, can accelerate urate excretion, thereby realize disappearing the silt pain relieving, eliminate the gout symptom.
Embodiment mono-: a kind of extraction process for the treatment of the Chinese medicine essence of gout, it comprises following operating procedure.
I, by the quality proportioning: 30 jin of Caulis Trachelospermis, 40 jin of Radix Cynanchi Paniculatis, three kinds of raw material of Chinese medicine of 30 jin of weighings of Caulis Sargentodoxae, in stainless steel tank, carry out routine and clean, taking-up is dried standby;
II, by standby raw material of Chinese medicine co-grinding, smashing fineness reaches 120 orders, then adds the water of 10 times of raw material of Chinese medicine gross masses to mix, and produces slip;
III, slip is put into to stainless-steel pan, be heated to 100 ℃, decocted 1 hour, then put into Filter Press and obtain the herb liquid slurry;
IV, indoor at bacteria-and dust-free, the herb liquid slurry is poured in the stainless-steel pan with agitating device and stirred, be cooled to 15-18 ℃, add again 0.3 jin of protease, 0.3 jin of cellulase and 0.2 jin of diastase, under the condition of 30 beats/mins of rotating speeds, stirred 2 hours, and with tablet vinegar acid for adjusting pH value 5.0, standing 10 hours;
V, standing liquid is put into to centrifuge dehydration in aseptic temperature control workshop after, the precipitate that produces is put into to the electric heating aerator and sets 45 ℃ of constant temperature and carried out drying 5 hours, obtain weight and be 6 jin, the Chinese medicine essence finished product of the treatment gout of dry powder state.
Embodiment bis-: a kind of extraction process for the treatment of the Chinese medicine essence of gout, it comprises following operating procedure.
I, by the quality proportioning: 20 jin of Caulis Trachelospermis, 20 jin of Radix Cynanchi Paniculatis, three kinds of raw material of Chinese medicine of 20 jin of weighings of Caulis Sargentodoxae, in stainless steel tank, carry out routine and clean, taking-up is dried standby;
II, by standby raw material of Chinese medicine co-grinding, smashing fineness reaches 180 orders, then adds the water of 600 jin of raw material of Chinese medicine gross masses to mix, and produces slip;
III, slip is put into to stainless-steel pan, be heated to 100 ℃, decocted 60 minutes, then put into Filter Press and obtain the herb liquid slurry;
IV, indoor at bacteria-and dust-free, the herb liquid slurry is poured in the stainless-steel pan with agitating device and stirred, be cooled to 15-18 ℃, add again 0.18 jin of protease, 0.24 jin of cellulase and 0.12 jin of diastase, under the condition of 30 beats/mins of rotating speeds, stirred 2 hours, and with tablet vinegar acid for adjusting pH value 5.0, standing 10 hours;
V, standing liquid is put into to centrifuge dehydration in aseptic temperature control workshop after, the precipitate that produces is put into to the electric heating aerator and set 45 ℃ of constant temperature and carried out drying 6 hours, obtain weight and be 3.7 jin, the Chinese medicine essence finished product of the treatment gout of dry powder state.
The embodiment of the present invention is intended to be convenient to understand innovation essence of the present invention; but do not limit the scope of the invention; all simple modification or equivalence are replaced, or utilize this finished product powder processing and fabricating capsule, pill, injection etc., all should be contained among the scope of the present invention.
Medical record is introduced: the present invention treats the Chinese medicine extraction element of gout through development for many years, and drops into clinical trial, cures efficiency and reaches more than 98%.
Suzhou patient Ma, 65 years old, suffer from gout more than ten years.Blood uric acid is more than 600, the thumb redness and swelling of joints, unbearable as pain, the joint swelling that gradually becomes is stiff, joint stuffiness.Successively take colchicine, occur stopping using after leucocytes reduction; Take crovaril and water-sodium retention occurs, the medicine of also can only stopping using.By friend, introduce the essence of trial edition invention Caulis Trachelospermi, Caulis Sargentodoxae, Radix Cynanchi Paniculati extraction, three times on the one, each 1.5g.Through rechecking, uric acid content slowly is reduced to 200, and the gout symptom does not occur yet again.
As can be seen here, the present invention treats the Chinese medicine essence of gout and development and the application of extraction process thereof, compare to existing other Chinese medicine semi-finished product or Chinese medicine eating method, this Chinese medicine essence has effectively suppressed the heavily absorption of renal tubules to uric acid under zero toxic and side effects, can accelerate urate excretion, thereby realize disappearing the silt pain relieving, eliminate the gout symptom; Extraction process step of the present invention is simple in addition, and it is convenient to implement, and extraction is higher, is suitable for scale in batches and produces.
Claims (6)
1. Chinese medicine essence for the treatment of gout is characterized in that: described Chinese medicine essence extracts the mixture from Caulis Trachelospermi, Radix Cynanchi Paniculati and Caulis Sargentodoxae, and described mixture component by weight is: Caulis Trachelospermi 20-50 part, Radix Cynanchi Paniculati 20-60 part, Caulis Sargentodoxae 30-60 part.
2. treat according to claim 1 the Chinese medicine essence of gout, it is characterized in that: in described mixture, each component is by weight being 1:1:1.
3. extraction process for the treatment of the Chinese medicine essence of gout, its feature comprises operating procedure:
I, by the quality proportioning: Caulis Trachelospermi 20-50 part, Radix Cynanchi Paniculati 20-60 part, three kinds of raw material of Chinese medicine of Caulis Sargentodoxae 30-60 part weighing, in stainless steel tank, carry out routine and clean, taking-up is dried standby;
II, by standby raw material of Chinese medicine co-grinding, smashing fineness reaches the 100-200 order, then adds the water of 10 times of raw material of Chinese medicine gross masses to mix, and produces slip;
III, slip is put into to stainless-steel pan, be heated to 100 ℃, decocted 60 minutes, then put into Filter Press and obtain the herb liquid slurry;
IV, indoor at bacteria-and dust-free, the herb liquid slurry is poured in the stainless-steel pan with agitating device and stirred, be cooled to 15-18 ℃, then add a certain amount of protease, cellulase and diastase, stirred 2 hours and used tablet vinegar acid for adjusting pH value 5.0, standing 8-16 hour;
V, standing liquid is put into to centrifuge dehydration in aseptic temperature control workshop after, the precipitate that produces is put into to 45 ℃ of electric heating aerator setting constant temperature and carry out dry 4-7 hour, obtain the Chinese medicine essence of the treatment gout of dry powder state, the weight of this Chinese medicine essence is the 5-7% of three kinds of raw material of Chinese medicine gross weights.
4. treat according to claim 3 the extraction process of the Chinese medicine essence of gout, it is characterized in that: described protease addition is the 0.2-0.4% of three kinds of raw material of Chinese medicine gross weights.
5. treat according to claim 3 the extraction process of the Chinese medicine essence of gout, it is characterized in that: described cellulase addition is the 0.2-0.4% of three kinds of raw material of Chinese medicine gross weights.
6. treat according to claim 3 the extraction process of the Chinese medicine essence of gout, it is characterized in that: described diastase addition is the 0.15-0.25% of three kinds of raw material of Chinese medicine gross weights.
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| CN104274624A (en) * | 2014-09-29 | 2015-01-14 | 覃宇 | Traditional Chinese medicinal composition for treating gout |
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| CN102579936A (en) * | 2012-03-06 | 2012-07-18 | 中国科学院武汉植物园 | Shennong medicinal liquor and preparation method thereof |
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Patent Citations (3)
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| CN101099802A (en) * | 2007-07-23 | 2008-01-09 | 杨国军 | External-applied liniment for treating osteoproliferation disease |
| CN101623469A (en) * | 2009-07-30 | 2010-01-13 | 贵州盛世龙方制药股份有限公司 | Detection method of Guwei collaterals-activating tincture |
| CN102579936A (en) * | 2012-03-06 | 2012-07-18 | 中国科学院武汉植物园 | Shennong medicinal liquor and preparation method thereof |
Non-Patent Citations (3)
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| 张娴娴,孙维峰: "高尿酸血症的中医药治疗研究", 《华南国防医学杂志》, vol. 23, no. 2, 30 April 2009 (2009-04-30), pages 75 - 77 * |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104274624A (en) * | 2014-09-29 | 2015-01-14 | 覃宇 | Traditional Chinese medicinal composition for treating gout |
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