CN104258354A - Granules with spleen activating and stomach invigorating functions and preparation method of granules - Google Patents
Granules with spleen activating and stomach invigorating functions and preparation method of granules Download PDFInfo
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- CN104258354A CN104258354A CN201410544035.1A CN201410544035A CN104258354A CN 104258354 A CN104258354 A CN 104258354A CN 201410544035 A CN201410544035 A CN 201410544035A CN 104258354 A CN104258354 A CN 104258354A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention discloses granules with spleen activating and stomach invigorating functions and a preparation method of the granules. The granules are prepared by raw materials in parts by weight as follows: bitter gourd, onions, hawthorns, potatoes, Chinese yam, tangerine peel, white fungus, fresh ginger, radix codonopsis and honey, wherein the bitter gourd, onions, the hawthorns, the potatoes, the Chinese yam and the fresh ginger are firstly cleaned, aired and sliced and then dried and dewatered; obtained dried slices, tangerine peel, white fungus and radix codonopsis are ground into powder by a grinder respectively, distilled water is added, the mixture is heated and boiled, honey is added and blended, and the mixture is concentrated to a pasty fluid; and finally, the pasty fluid is dried and smashed into particles, measurement packing and bagging are performed, and the granules are obtained. The granules are simple to prepare, raw materials are easy to obtain, the cost is low, the granules can promote digestion, absorption of intestines and the stomach is facilitated, and the granules have good spleen activating and stomach invigorating effects and are suitable for being used for wide crowds.
Description
Technical field
The present invention relates to technical field of Chinese medicines, specifically a kind ofly open dissolved granule of spleen stomach invigorating and preparation method thereof.
Background technology
Along with expanding economy, the living standard of people is also more and more higher, and wherein meals are also become better and better, and a lot of people can absorb much higher fatty acid, high-carbohydrate materials.As time goes on, even if food good again, also have when being weary of, therefore just there will be inappetence, or even be reluctant the situation of having a meal, therefore daily life feed will keep reasonably collocation could keep normal appetite.For the situation of inappetence, have a lot of medicine and Chinese medicine in the market, have good effect, but these medicines are cured the symptoms, not the disease, and price is more expensive, is not easily accepted by many people.Therefore just need cost low and treatment inappetence is effective, the Chinese medicine of spleen stomach invigorating can be opened, meet the requirement of more people.
Summary of the invention
The object of the present invention is to provide a kind of cost low and therapeutic effect good open dissolved granule of spleen stomach invigorating and preparation method thereof, to solve the problem proposed in above-mentioned background technology.
For achieving the above object, the invention provides following technical scheme:
A kind of dissolved granule opening spleen stomach invigorating, formed by the preparation of raw material of following weight portion: 150 ~ 170 parts, Fructus Momordicae charantiae, Bulbus Allii Cepae 180 ~ 200 parts, Fructus Crataegi 190 ~ 210 parts, Rhizoma Solani tuber osi 140 ~ 160 parts, Rhizoma Dioscoreae 80 ~ 100 parts, Pericarpium Citri Reticulatae 60 ~ 70 parts, 60 ~ 70 parts, Tremella, 40 ~ 60 parts, Rhizoma Zingiberis Recens, Radix Codonopsis 160 ~ 180 parts, Mel 160 ~ 180 parts.
A kind of preparation method opening the dissolved granule of spleen stomach invigorating, concrete preparation process is as follows: (1) dries after Fructus Momordicae charantiae, Bulbus Allii Cepae, Fructus Crataegi, Rhizoma Solani tuber osi, Rhizoma Dioscoreae and Rhizoma Zingiberis Recens being cleaned up, use microtome respectively, the drying baker putting into 35 ~ 45 DEG C dries 6 ~ 8h to slough moisture, obtains dry tablet for subsequent use; (2) dry tablet and Pericarpium Citri Reticulatae will be obtained, Tremella, Radix Codonopsis be ground into 180 ~ 200 object powder with pulverizer respectively; (3) the powder mixing will obtained, adds the distilled water of raw material 6 ~ 8 times, first boils 20 ~ 30min with high heat, use slow fire infusion 3 ~ 4h again, naturally cool to 60 DEG C, add Mel, at the temperature of 40 ~ 50 DEG C, be concentrated into the mastic that relative density is 1.10 ~ 1.20; (4) dried to blocks of solid in the drying baker of 50 ~ 60 DEG C by mastic, then be ground into 80 ~ 100 object granules with pulverizer, metering packing becomes bag, must open the dissolved granule of spleen stomach invigorating.
Pharmacological action: Bulbus Allii Cepae: the Herba Alii fistulosi allicin energy gastric acid secretion contained, improve gastrointestinal tract Zhang Li, promote gastrointestinal peristalsis, facilitating digestion, thus play appetizing effect, have atrophic gastritis, the inappetence that causes for be short of power, dyspepsia etc. and alleviate very well and therapeutical effect; Fructus Momordicae charantiae: the Charantin contained and bitter principle can increase appetite, spleen benefiting and stimulating the appetite, the alkaloids substance quinine contained has diuresis to invigorate blood circulation, effect of anti-inflammatory antipyretic and the improving eyesight that clears away heart-fire; Fructus Crataegi: the lipase contained can promote steatolysis, Crataegolic acid improves the activity of protease, helps digestion stagnant, facilitating digestion, appetite promoting and the spleen strengthening; Rhizoma Solani tuber osi: containing abundant dietary fiber, promotes gastrointestinal peristalsis, has a pain have clear improvement and therapeutical effect to weakness of the spleen and stomach, dyspepsia, gastral cavity abdomen; Rhizoma Dioscoreae: the effect having out spleen stomach invigorating; Pericarpium Citri Reticulatae: volatile oil has the effect of fragrant stomach invigorating and the wind dispelling therapeutic method to keep the adverse QI flowing downwards; Tremella: the effect with spleen reinforcing appetizing, containing abundant dietary fiber, can promote gastrointestinal peristalsis, facilitating digestion; Rhizoma Zingiberis Recens: the secretion stimulating gastric juice and Digestive system, increases gastrointestinal peristalsis, appetite stimulator; Radix Codonopsis: the effect with stomach invigorating appetizing; Mel; Deposit into gastric acid secretion normal, strengthen the effect of enterokinesia, increase the curative effect of appetite.
Compared with prior art, the invention has the beneficial effects as follows: dissolved granule preparation of the present invention is simple, and raw material is easy to get, and cost is low, and energy facilitating digestion, be beneficial to the absorption of the intestines and stomach, there is the effect well opening spleen stomach invigorating, be applicable to many people and use.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, be clearly and completely described the technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
Open a dissolved granule for spleen stomach invigorating, formed by the preparation of raw material of following weight portion: 150 parts, Fructus Momordicae charantiae, Bulbus Allii Cepae 180 parts, Fructus Crataegi 190 parts, Rhizoma Solani tuber osi 140 parts, Rhizoma Dioscoreae 80 parts, Pericarpium Citri Reticulatae 60 parts, 60 parts, Tremella, 40 parts, Rhizoma Zingiberis Recens, Radix Codonopsis 160 parts, Mel 160 parts.
A kind of preparation method opening the dissolved granule of spleen stomach invigorating, concrete preparation process is as follows: (1) dries after Fructus Momordicae charantiae, Bulbus Allii Cepae, Fructus Crataegi, Rhizoma Solani tuber osi, Rhizoma Dioscoreae and Rhizoma Zingiberis Recens being cleaned up, use microtome respectively, the drying baker putting into 45 DEG C dries 8h to slough moisture, obtains dry tablet for subsequent use; (2) dry tablet and Pericarpium Citri Reticulatae will be obtained, Tremella, Radix Codonopsis be ground into 200 object powder with pulverizer respectively; (3) the powder mixing will obtained, adds the distilled water of raw material 6 times, first boils 20min with high heat, then use slow fire infusion 3h, naturally cool to 60 DEG C, add Mel, be concentrated into the mastic that relative density is 1.20 at the temperature of 50 DEG C; (4) dried to blocks of solid in the drying baker of 50 DEG C by mastic, then be ground into 80 object granules with pulverizer, metering packing becomes bag, must open the dissolved granule of spleen stomach invigorating.
Embodiment 2
Open a dissolved granule for spleen stomach invigorating, formed by the preparation of raw material of following weight portion: 160 parts, Fructus Momordicae charantiae, Bulbus Allii Cepae 190 parts, Fructus Crataegi 200 parts, Rhizoma Solani tuber osi 150 parts, Rhizoma Dioscoreae 90 parts, Pericarpium Citri Reticulatae 65 parts, 65 parts, Tremella, 50 parts, Rhizoma Zingiberis Recens, Radix Codonopsis 170 parts, Mel 170 parts.
A kind of preparation method opening the dissolved granule of spleen stomach invigorating, concrete preparation process is as follows: (1) dries after Fructus Momordicae charantiae, Bulbus Allii Cepae, Fructus Crataegi, Rhizoma Solani tuber osi, Rhizoma Dioscoreae and Rhizoma Zingiberis Recens being cleaned up, use microtome respectively, the drying baker putting into 45 DEG C dries 8h to slough moisture, obtains dry tablet for subsequent use; (2) dry tablet and Pericarpium Citri Reticulatae will be obtained, Tremella, Radix Codonopsis be ground into 200 object powder with pulverizer respectively; (3) the powder mixing will obtained, adds the distilled water of raw material 7 times, first boils 25in with high heat, then use slow fire infusion 3.5h, naturally cool to 60 DEG C, add Mel, be concentrated into the mastic that relative density is 1.20 at the temperature of 50 DEG C; (4) dried to blocks of solid in the drying baker of 50 DEG C by mastic, then be ground into 80 object granules with pulverizer, metering packing becomes bag, must open the dissolved granule of spleen stomach invigorating.
Embodiment 3
Open a dissolved granule for spleen stomach invigorating, formed by the preparation of raw material of following weight portion: 170 parts, Fructus Momordicae charantiae, Bulbus Allii Cepae 200 parts, Fructus Crataegi 210 parts, Rhizoma Solani tuber osi 160 parts, Rhizoma Dioscoreae 100 parts, Pericarpium Citri Reticulatae 70 parts, 70 parts, Tremella, 60 parts, Rhizoma Zingiberis Recens, Radix Codonopsis 180 parts, Mel 180 parts.
A kind of preparation method opening the dissolved granule of spleen stomach invigorating, concrete preparation process is as follows: (1) dries after Fructus Momordicae charantiae, Bulbus Allii Cepae, Fructus Crataegi, Rhizoma Solani tuber osi, Rhizoma Dioscoreae and Rhizoma Zingiberis Recens being cleaned up, use microtome respectively, the drying baker putting into 45 DEG C dries 8h to slough moisture, obtains dry tablet for subsequent use; (2) dry tablet and Pericarpium Citri Reticulatae will be obtained, Tremella, Radix Codonopsis be ground into 200 object powder with pulverizer respectively; (3) the powder mixing will obtained, adds the distilled water of raw material 8 times, first boils 30min with high heat, then use slow fire infusion 4h, naturally cool to 60 DEG C, add Mel, be concentrated into the mastic that relative density is 1.20 at the temperature of 50 DEG C; (4) dried to blocks of solid in the drying baker of 50 DEG C by mastic, then be ground into 80 object granules with pulverizer, metering packing becomes bag, must open the dissolved granule of spleen stomach invigorating.
Embodiment 4
Clinical trial
(1) subjects: adopt the present invention to treat 100 routine patients altogether, wherein man 55 example, female 45 example; The oldest person 70 years old, age reckling 10 years old.
(2) diagnostic criteria: inappetence, imperceptible hungry, do not feel like a meal, even have vomiting sensation.
(3) Therapeutic Method: every day is bfore meals, one day three times, once a bag.
(4) standard is treated
Cure: symptom all disappears, appetite is fine, and appetite increases;
Take a turn for the better: disease obviously alleviates, and appetite improves, increase of having a meal;
Invalid: before and after medication, symptom is without change.
(5) therapeutic outcome: how to take effect after 2 days after taking medicine in the routine case of patient 100; Wherein cure 80 examples, effective 15 examples, effective 3 examples, invalid 2 examples, total effective rate reaches 97%.
Model case:
(1) Tan, man, 30 years old, inappetence, feed was few, and see that food has vomiting sensation, take Chinese medicine preparation of the present invention after 2 days, above-mentioned symptom disappears, and have a very good appetite, appetite obviously improves.
(2) poplar, female, 40 years old, inappetence, did not feel like a meal, and take Chinese medicine preparation of the present invention after 1 day, above-mentioned symptom is clearly better, and appetite increases, and had a meal and kept normal appetite.
(3) Pueraria lobota, man, 10 years old, inappetence, did not feel like a meal, and take Chinese medicine preparation of the present invention 1 day, appetite increases, and appetite increases, and the mental status is fine.
Claims (2)
1. open the dissolved granule of spleen stomach invigorating for one kind, it is characterized in that, formed by the preparation of raw material of following weight portion: 150 ~ 170 parts, Fructus Momordicae charantiae, Bulbus Allii Cepae 180 ~ 200 parts, Fructus Crataegi 190 ~ 210 parts, Rhizoma Solani tuber osi 140 ~ 160 parts, Rhizoma Dioscoreae 80 ~ 100 parts, Pericarpium Citri Reticulatae 60 ~ 70 parts, 60 ~ 70 parts, Tremella, 40 ~ 60 parts, Rhizoma Zingiberis Recens, Radix Codonopsis 160 ~ 180 parts, Mel 160 ~ 180 parts.
2. open the preparation method of the dissolved granule of spleen stomach invigorating as claimed in claim 1 for one kind, it is characterized in that, concrete preparation process is as follows: (1) dries after Fructus Momordicae charantiae, Bulbus Allii Cepae, Fructus Crataegi, Rhizoma Solani tuber osi, Rhizoma Dioscoreae and Rhizoma Zingiberis Recens being cleaned up, use microtome respectively, the drying baker putting into 35 ~ 45 DEG C dries 6 ~ 8h to slough moisture, obtains dry tablet for subsequent use; (2) dry tablet and Pericarpium Citri Reticulatae will be obtained, Tremella, Radix Codonopsis be ground into 180 ~ 200 object powder with pulverizer respectively; (3) the powder mixing will obtained, adds the distilled water of raw material 6 ~ 8 times, first boils 20 ~ 30min with high heat, use slow fire infusion 3 ~ 4h again, naturally cool to 60 DEG C, add Mel, at the temperature of 40 ~ 50 DEG C, be concentrated into the mastic that relative density is 1.10 ~ 1.20; (4) dried to blocks of solid in the drying baker of 50 ~ 60 DEG C by mastic, then be ground into 80 ~ 100 object granules with pulverizer, metering packing becomes bag, must open the dissolved granule of spleen stomach invigorating.
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104857472A (en) * | 2015-05-18 | 2015-08-26 | 彭婷婷 | Instant granules with spleen activating and stomach invigorating efficacy and preparation method of instant granules |
CN110064041A (en) * | 2019-05-16 | 2019-07-30 | 江苏千药堂国医研究院有限公司 | For dyspeptic pharmaceutical composition extract and preparation method and purposes |
CN110841049A (en) * | 2019-12-11 | 2020-02-28 | 竹溪众创农村电商孵化器有限公司 | Medicine for treating children dyspepsia |
-
2014
- 2014-10-15 CN CN201410544035.1A patent/CN104258354A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104857472A (en) * | 2015-05-18 | 2015-08-26 | 彭婷婷 | Instant granules with spleen activating and stomach invigorating efficacy and preparation method of instant granules |
CN110064041A (en) * | 2019-05-16 | 2019-07-30 | 江苏千药堂国医研究院有限公司 | For dyspeptic pharmaceutical composition extract and preparation method and purposes |
CN110841049A (en) * | 2019-12-11 | 2020-02-28 | 竹溪众创农村电商孵化器有限公司 | Medicine for treating children dyspepsia |
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