Summary of the invention
The objective of the invention is at the deficiencies in the prior art, a kind of Huang Shuan that whitens that contains unique Chinese medicine composition safely and effectively is provided, it can effectively solve the skin problem that pigmentation causes, it is remarkable to have effect, safe and non-stimulating characteristics.
The technical scheme that the present invention solves its technical problem employing is as follows: a kind of Huang Shuan of whitening, wherein contain Chinese medicine composition, described Chinese medicine composition is made by six kinds of medicinal material extract in the following medical material prescription, by percentage to the quality: Radix Glycyrrhizae 5-55%, Fructus Phyllanthi fruit 15-35%, Poria 5-15%, Flos Carthami 5-15%, Herba Centellae 15-20%, Semen Coicis 5-10%.
As a kind of preferred, described medical material prescription contains the Chinese crude drug of following mass content: Radix Glycyrrhizae 40%, Fructus Phyllanthi fruit 20%, Poria 10%, Flos Carthami 5%, Herba Centellae 15%, Semen Coicis 10%.
Preferably, whiten and contain the Chinese medicine composition of mass content 10% in the Huang Shuan prescription.
The Huang Shuan that whitens that contains above-mentioned Chinese medicine composition also can contain other components, and in the preferred scheme of the present invention, the Huang Shuan that whitens with following mass content each component has the yellow effect of better whitening:
There is no particular restriction antiseptic in the Huang Shuan that the whitens prescription, and described antiseptic can be composite the forming of one or more antiseptic in phenoxyethanol, Bronopol, two hydroxy methylimidazole ureine, parabens, Methylisothiazolinone, the iodo propinyl butyl carbamate etc.
The Huang Shuan of whitening of the present invention can prepare according to cosmetic field existing preparation technology, and as a kind of preferred version, the described Huang Shuan of whitening prepares according to following steps:
1) prescription according to the Huang Shuan that whitens takes by weighing each component;
2) HANSHENGJIAO, hyaluronate sodium are uniformly dispersed with 1,3 butylene glycol, glycerol, same allantoin, EDTA-2NA are added to the water afterwards, are heated to 80-85 ℃, and it is mutually standby to make A;
3) cetearyl alcohol/cetearyl glucoside, 16/18 alcohol, glyceryl stearate, glyceryl stearate/PEG-100 stearate, ethylhexyl palmitate, white mineral oil, silicon are handled titanium dioxide, polydimethylsiloxane, isononyl isononanoate, isopropyl myristate, phospholipid Hybrid Heating to 80-85 ℃ of dissolving, it is mutually standby to make B;
4) under the stirring (40-45 rev/min) B is added to the A phase fast, opened homogenizing (2000-3000 rev/min) 6-7 minute, insulated and stirred (15-20 rev/min) is 25-30 minute again;
5) be cooled to 35-40 ℃ and add antiseptic and Chinese medicine extraction liquid, stir (20-30 rev/min) homogenizing (2000-3000 rev/min) 1-2 minute after 3-5 minute, continue to stir discharging.
The present invention is raw materials used all can be by commercially available acquisition, and as a kind of preferred version, Chinese medicine composition of the present invention is prepared from according to following steps:
1) takes by weighing each medical material component by the medical material prescription;
2) selection is removed the going mouldy of Chinese crude drug, is damaged by worms, sick scar part, and removes the field trash in the Chinese crude drug;
3) pulverize, will through the Chinese crude drug coarse crushing of selection to granularity less than 20mm, further be crushed to pulverulence again, sieve and keep powder below 20 orders for following process;
4) soaking into, is the amount immersion 4 hour of 1:8 with pure water according to the mass ratio of Chinese medicine powder and pure water with Chinese medicine powder at normal temperatures, constantly stirring in the immersion process;
5) extract, add mass concentration in the medical material after infiltration and be 30% low-concentration ethanol solution and carry out heating and refluxing extraction, the mass ratio of alcoholic solution and Chinese medicine powder is 2:1, and reflux, extract, 4 hours is extracted and finished the back and cool off below the extract to 40 ℃;
6) filter, with filtering accuracy 100 purpose filter materials extract is carried out preliminary coarse filtration, the removal large particulate matter, re-using 1000 order filter clothes, to carry out secondary filter (freezing and filtering) to filtrate under 5 ℃ cryogenic conditions be clear liquid.
Adopt above-mentioned steps to carry out the extraction of Chinese medicine active component, have the extraction conditions gentleness, extract the low characteristics of temperature, little to the activity influence of active component especially heat-sensitive ingredients, by-product is few; And adopt the mode of pure water immersion and low-concentration ethanol aqueous solution reflux, extract, to extract, be conducive to fully extract water solublity and pure dissolubility active component.Simultaneously in preparation process, multiple different Chinese medicines are miscible in together and extract simultaneously, be conducive to active component in each medical material and active substance dissolve each other coexistence, play synergism each other.Through the Chinese medicine composition of said extracted step preparation, can bring into play the effect of Chinese crude drug active substance greatly.
Compared with prior art, the present invention has following beneficial effect:
1, the Huang Shuanzhong of whitening provided by the present invention contains the Chinese medicine composition of six kinds of Chinese crude drugs, the six kinds of Chinese crude drugs of whitening in the yellow frost are arranged in pairs or groups according to special ratios, the multiple efficacies composition that is rich in is in harmonious proportion mutually, works in coordination with, make the Huang Shuan that whitens reach the melanic formation of effective inhibition, activating blood circulation to dissipate blood stasis, heat-clearing and toxic substances removing and the metabolic effect of chafe, make it have the yellow effect of whitening of comprehensively regulating.
2, adopt the present invention's Huang Shuan prescription of preferably whitening to prepare cream cream type easy to carry, that smear easily.It is a kind of Rutile type titanium dioxide that has adopted aluminium oxide and the compound coating of silicon oxide that the silicon that adds in the prescription is handled titanium dioxide, do not need high speed shear in the oils medium, well to disperse when being characterized in producing, the adhesive force of goods on skin is good, frictional force reduces, have antiperspirant and the secretion oils and fats ability of anti-skin, long in the skin retention time, can make woman's persona face nature, do not have false thick and heavy sense, can reach instantaneous whitening effect.
3, add special penetrating agent phospholipid, phospholipid is a kind of nontoxic, non-stimulated short penetrating agent, promotes the Transdermal absorption of medicine, plays to promote the yellow effect of whitening.
4, the present invention has used for reference the herbal tea production technology, and the way treatment product that namely adopts freezing to filter can avoid product macroscopic precipitation to occur in the shelf-life.
Facts have proved that the yellow frost of whitening provided by the present invention used 28 days continuously, can effectively eliminate the problem of the calm dull-looking skin that causes of pigments such as chloasma, butterfly spot, senile plaque, the yellow effect of whitening is significantly arranged, but and product life-time service of the present invention, having no side effect, zest is little.
Below several Chinese crude drugs are introduced:
Radix Glycyrrhizae: a kind of tonification Chinese herbal medicine, sweet in the mouth, property is flat, and is nontoxic.The main component of Radix Glycyrrhizae comprises glycyrrhizin, enoxolone, flavone compound liquiritin, liquiritigenin, isoliquiritin, the sharp ketone of isoliquiritin unit and Radix Glycyrrhizae.Wherein the flavone compound that is rich in of Radix Glycyrrhizae is a kind of natural whiting agent, effectively restraint of tyrosinase, dopachrome change and the oxidasic activity of DHICA.According to theory of Chinese medical science, Radix Glycyrrhizae also has antiinflammatory and antianaphylactic effect.
The Fructus Phyllanthi fruit: medicinal herbs are commonly used by Tibetan, are the dry mature fruit of Euphorbiaceae phyllanthus emblica platymiscium Fructus Phyllanthi.Fructus Phyllanthi really contains abundant micromolecule tannin, can effectively suppress α-MSH activity, reduces melanin and generates; Mottle, freckle and chloasma there is discoloration fast.
Poria: for medical material Poria piece cuts white portion behind the Poria, sweet in the mouth, light, property flat, be used as medicine have promoting diuresis to eliminate damp pathogen, the function of strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Poria not only can significantly improve body immunity, can make also that HbO2 Oxyhemoglobin discharges more oxygen in the blood, to be supplied to histiocyte.Simultaneously, also can make cell tissue (comprising skin, mucosa, hair etc.) increased activity, vigor increases, and is in health status, thereby makes skin, hair seem more moist, reaches the effect of beauty treatment.
Flos Carthami: the dried floral of feverfew Flos Carthami.Warm in nature, acrid in the mouth, promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.By blood circulation promoting and blood stasis dispelling, accelerate blood circulation, enhance metabolism, increase and get rid of the melanin that melanocyte produces, the melanin that promotes to be stranded in the body decomposes, and makes it to precipitate the formation mottle, or the pigment that makes the shallow lake decomposes and excretes, and reaches speckle dispelling profit face, treats the effect of skin ulcer blood stasis dispelling.In India, Flos Carthami just is used to skin care, beauty treatment, slow down aging from ancient times.
Herba Centellae: the perennial herbaceous plant that crawls, nature and flavor: bitter, hot, cold.Herba Centellae contains the flavonoid glycoside of multiple materials such as Asiaticoside, thankuniside, isothankuniside, madecassoside and Radix Dauci Sativae hydro carbons, chlorophyll, Quercetin and glucose.The Herba Centellae extracting solution makes an addition in the cosmetics of cream kind, cleansing milk and the smelting property treated in the cosmetics, some dermatosis, carbuncle sore tumefacting virus, erysipelas, eczema, intractable wound all there are antibacterial bacteriostatic and smelting treatment effect, thus the skin effect that plays the skin care skin moistening, improves looks, whitens
Semen Coicis: the kernel of grass Semen Coicis.Rich in proteins can assist to eliminate mottle, to the tangible curative effect of having of face acne and pachylosis, simultaneously can also be anti-loss, even thin face effect is arranged.Moreover, the extractive matter of Semen Coicis also can reach sun-proof and effect anti-ultraviolet, has the natural beauty white effect, improves skin metabolism and moisture preserving function.
The specific embodiment
Below in conjunction with embodiment technical scheme of the present invention is described further:
Embodiment 1
1, the preparation of Chinese medicine composition:
1) the medical material prescription according to the embodiment 1 shown in the following table 1 takes by weighing each medical material component: Radix Glycyrrhizae 40g, Fructus Phyllanthi fruit 20g, white
Poria 10g, Flos Carthami 5g, Herba Centellae 15g, Semen Coicis 10g, medical material amounts to 100g,
2) selection is removed the going mouldy of Chinese crude drug, is damaged by worms, sick scar part, removes the field trash in the Chinese crude drug;
3) pulverize, will through the Chinese crude drug coarse crushing of selection to granularity less than 20mm, further pulverizing to pulverulence again, sieve and keep powder below 20 orders for following process;
4) soak into, at normal temperatures Chinese medicine powder was soaked 4 hours with pure water (mass ratio of Chinese medicine powder and pure water is 1:8), constantly stir in the immersion process;
5) extracting, is that 30% low-concentration ethanol solution carries out heating and refluxing extraction with the medical material mass concentration after soaking into, and the mass ratio of ethanol and Chinese medicine powder is 2:1, and reflux, extract, 4 hours is extracted and cooled off after finishing below the extract to 40 ℃;
6) filter, with filtering accuracy 100 purpose filter materials extract carried out preliminary coarse filtration, the removal large particulate matter, re-use 1000 order filter clothes under freezing conditions (5 ℃) secondary fine straining to filtrate be clear liquid.
2, the whiten preparation of Huang Shuan:
Take by weighing each component (in mass content) by following prescription: Chinese medicine composition 10%, cetearyl alcohol/cetearyl glucoside 2.2%, 16/18 alcohol 3%, glyceryl stearate 2%, glyceryl stearate/PEG-100 stearate 1%, ethylhexyl palmitate 2%, white mineral oil 4%, silicon are handled titanium dioxide 2%, polydimethylsiloxane 2%, isononyl isononanoate 4%, isopropyl myristate 2%, phosphatidase 13 %, allantoin 0.2%, hyaluronate sodium 0.03%, HANSHENGJIAO 0.15%, glycerol 5%, 1,3 butylene glycol 5%, EDTA-2NA0.2%, antiseptic 0.2%, water surplus.
Yellow white preparation technology whitens:
1) prescription according to the Huang Shuan that whitens takes by weighing each component;
2) HANSHENGJIAO, hyaluronate sodium are uniformly dispersed with 1,3 butylene glycol, glycerol, same allantoin, EDTA-2Na are added to the water afterwards, are heated to 80-85 ℃, and it is mutually standby to make A;
3) cetearyl alcohol/cetearyl glucoside, 16/18 alcohol, glyceryl stearate, glyceryl stearate/PEG-100 stearate, ethylhexyl palmitate, white mineral oil, silicon are handled titanium dioxide, polydimethylsiloxane, isononyl isononanoate, isopropyl myristate, phospholipid Hybrid Heating to 80-85 ℃ of dissolving, it is mutually standby to make B;
4) under the stirring (40-45 rev/min) B is added to the A phase fast, opened homogenizing (2000-3000 rev/min) 6-7 minute, insulated and stirred (15-20 rev/min) is 25-30 minute again;
5) be cooled to 35-40 ℃ and add antiseptic and Chinese medicine extraction liquid, stir (20-30 rev/min) homogenizing (2000-3000 rev/min) 1-2 minute after 3-5 minute, continue to stir discharging.
Embodiment 2
Substantially the same manner as Example 1, the medical material prescription according to the embodiment 2 shown in the following table 1 when difference is that Chinese medicine composition prepares takes by weighing each medical material component.
Embodiment 3
Substantially the same manner as Example 1, the medical material prescription according to the embodiment 3 shown in the following table 1 when difference is that Chinese medicine composition prepares takes by weighing each medical material component.
Table 1 medical material prescription (unit: g)
? |
Embodiment 1 |
Embodiment 2 |
Embodiment 3 |
Radix Glycyrrhizae |
40 |
5 |
50 |
The Fructus Phyllanthi fruit |
20 |
35 |
15 |
Poria |
10 |
15 |
5 |
Flos Carthami |
5 |
15 |
10 |
Herba Centellae |
15 |
20 |
15 |
Semen Coicis |
10 |
10 |
5 |
The measure of merit result:
Tested object: age 25-45 year middle-aged women.Each test group is all chosen middle-aged women 100 examples that face has dull-looking skin such as chloasma, butterfly spot, senile plaque.
Method of testing: get cream frost 3-5 gram that embodiment 1~3 provides after washing one's face every morning and be applied to spottiness on the face, obscure position, repaste once before the sleep evening, and 28 days is a course for the treatment of.
Testing standard: 1. recovery from illness: 2. produce effects: 3. effective: 4. invalid:
Result of use such as following table 2:
Table 2
? |
Recovery from illness |
Produce effects |
Effectively |
Invalid |
Total effective rate |
Embodiment 1 |
83 |
10 |
5 |
2 |
93% |
Embodiment 2 |
65 |
15 |
7 |
13 |
80% |
Embodiment 3 |
70 |
17 |
5 |
8 |
87% |
Facts have proved, the yellow frost of whitening provided by the present invention used 28 days continuously, just can effectively eliminate the problem of the calm dull-looking skin that causes of pigments such as chloasma, butterfly spot, senile plaque, the yellow effect of whitening is significantly arranged, and in life-time service product process of the present invention, do not find toxic and side effects, and zest is little.
The above, it only is preferred embodiment of the present invention, be not that the present invention is done any pro forma restriction, so all contents that does not break away from technical solution of the present invention,, all still belong in the scope of technical solution of the present invention any simple modification, equivalent variations and modification that above embodiment does according to technical spirit of the present invention.