CN103313719A - 用于治疗结肠直肠癌的peg或peg嵌段共聚物 - Google Patents

用于治疗结肠直肠癌的peg或peg嵌段共聚物 Download PDF

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Publication number
CN103313719A
CN103313719A CN201180064013XA CN201180064013A CN103313719A CN 103313719 A CN103313719 A CN 103313719A CN 201180064013X A CN201180064013X A CN 201180064013XA CN 201180064013 A CN201180064013 A CN 201180064013A CN 103313719 A CN103313719 A CN 103313719A
Authority
CN
China
Prior art keywords
peg
composition
crc
mannitol
block copolymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201180064013XA
Other languages
English (en)
Chinese (zh)
Inventor
P·斯坦因
I·考克斯
S·史密斯
L·琼斯
J·普莱斯尔
C·德弗里斯
R·查尔顿
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norgine BV
Original Assignee
Norgine BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norgine BV filed Critical Norgine BV
Publication of CN103313719A publication Critical patent/CN103313719A/zh
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • A61K31/77Polymers containing oxygen of oxiranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
CN201180064013XA 2010-11-04 2011-11-04 用于治疗结肠直肠癌的peg或peg嵌段共聚物 Pending CN103313719A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1018650.0 2010-11-04
GBGB1018650.0A GB201018650D0 (en) 2010-11-04 2010-11-04 Methods and compositions
US41212810P 2010-11-10 2010-11-10
US61/412128 2010-11-10
PCT/GB2011/001561 WO2012059725A1 (en) 2010-11-04 2011-11-04 Peg or peg block copolymers for treating colorectal cancer

Publications (1)

Publication Number Publication Date
CN103313719A true CN103313719A (zh) 2013-09-18

Family

ID=43414365

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201180064013XA Pending CN103313719A (zh) 2010-11-04 2011-11-04 用于治疗结肠直肠癌的peg或peg嵌段共聚物

Country Status (22)

Country Link
US (2) US20130216493A1 (enExample)
EP (1) EP2635289B1 (enExample)
JP (1) JP5917537B2 (enExample)
KR (1) KR20130109171A (enExample)
CN (1) CN103313719A (enExample)
AR (1) AR083770A1 (enExample)
AU (1) AU2011324996B2 (enExample)
BE (1) BE1019494A3 (enExample)
BR (1) BR112013011012A2 (enExample)
CA (1) CA2816839A1 (enExample)
EA (1) EA201300540A1 (enExample)
ES (1) ES2401269B1 (enExample)
GB (1) GB201018650D0 (enExample)
MX (1) MX349690B (enExample)
MY (1) MY163067A (enExample)
NL (1) NL2007715C2 (enExample)
NZ (1) NZ611145A (enExample)
SG (1) SG189533A1 (enExample)
TW (1) TWI606832B (enExample)
UA (1) UA107998C2 (enExample)
WO (1) WO2012059725A1 (enExample)
ZA (1) ZA201304052B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113490501A (zh) * 2019-03-05 2021-10-08 陶氏环球技术有限责任公司 用于诱导胱天蛋白酶活性的聚乙二醇衍生物

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI535461B (zh) 2011-03-11 2016-06-01 諾金私人有限公司 結腸清潔溶液、用於製備該溶液之組成物、包含該組成物或溶液之套組、與製備該溶液之方法
AR092500A1 (es) 2012-09-11 2015-04-22 Norgine Bv Solucion de limpieza de colon
TW201431556A (zh) * 2012-10-26 2014-08-16 Univ Northshore Healthsystem 用於頭部和頸部鱗狀細胞癌之療法的包含聚乙二醇之組成物
CN103083733A (zh) * 2013-02-19 2013-05-08 华熙福瑞达生物医药有限公司 一种医用体腔器械导入水性润滑剂
US12201647B2 (en) 2019-03-05 2025-01-21 Dow Global Technologies Llc Inducing caspase activity
EP3934662A1 (en) 2019-03-05 2022-01-12 Dow Global Technologies LLC Inducing caspase activity

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010051659A1 (en) * 1998-10-27 2001-12-13 Denis Corpet Non-fermented osmotic laxative and method for treating and preventing colorectal cancers

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5276435B2 (ja) * 2005-05-06 2013-08-28 セイリックス ファーマシューティカルズ, インコーポレイティッド ポリエチレングリコールの結腸の下剤組成物
US8457025B2 (en) * 2009-08-28 2013-06-04 Telefonaktiebolaget L M Ericsson (Publ) Method and network node for selecting a network prefix to be advertised in a communication network

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010051659A1 (en) * 1998-10-27 2001-12-13 Denis Corpet Non-fermented osmotic laxative and method for treating and preventing colorectal cancers

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113490501A (zh) * 2019-03-05 2021-10-08 陶氏环球技术有限责任公司 用于诱导胱天蛋白酶活性的聚乙二醇衍生物
CN113490501B (zh) * 2019-03-05 2024-05-24 陶氏环球技术有限责任公司 用于诱导胱天蛋白酶活性的聚乙二醇衍生物

Also Published As

Publication number Publication date
JP5917537B2 (ja) 2016-05-18
UA107998C2 (uk) 2015-03-10
NL2007715A (en) 2012-05-07
US20160228467A1 (en) 2016-08-11
MY163067A (en) 2017-08-15
ES2401269A1 (es) 2013-04-18
TWI606832B (zh) 2017-12-01
GB201018650D0 (en) 2010-12-22
BR112013011012A2 (pt) 2016-08-23
MX349690B (es) 2017-08-09
NZ611145A (en) 2015-07-31
SG189533A1 (en) 2013-05-31
WO2012059725A8 (en) 2013-05-30
AR083770A1 (es) 2013-03-20
NL2007715C2 (en) 2012-10-16
US20130216493A1 (en) 2013-08-22
EP2635289A1 (en) 2013-09-11
EP2635289B1 (en) 2020-03-11
ZA201304052B (en) 2014-02-26
WO2012059725A1 (en) 2012-05-10
TW201304785A (zh) 2013-02-01
BE1019494A3 (fr) 2012-07-03
AU2011324996A1 (en) 2013-05-02
ES2401269B1 (es) 2014-02-19
AU2011324996B2 (en) 2015-10-08
MX2013004963A (es) 2013-08-27
CA2816839A1 (en) 2012-05-10
KR20130109171A (ko) 2013-10-07
EA201300540A1 (ru) 2013-09-30
JP2013544809A (ja) 2013-12-19

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SE01 Entry into force of request for substantive examination
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RJ01 Rejection of invention patent application after publication

Application publication date: 20130918