CN103275984A - 结合mcp-1的核酸 - Google Patents

结合mcp-1的核酸 Download PDF

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Publication number
CN103275984A
CN103275984A CN2013101587615A CN201310158761A CN103275984A CN 103275984 A CN103275984 A CN 103275984A CN 2013101587615 A CN2013101587615 A CN 2013101587615A CN 201310158761 A CN201310158761 A CN 201310158761A CN 103275984 A CN103275984 A CN 103275984A
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China
Prior art keywords
nucleic acid
mcp
box
tract
nucleotide sequence
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Pending
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CN2013101587615A
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English (en)
Chinese (zh)
Inventor
W·普尔施克
F·雅罗施
D·尤尔贝格
S·克吕斯曼
K·布赫纳
C·马阿施
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TME Pharma AG
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Noxxon Pharma AG
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Publication of CN103275984A publication Critical patent/CN103275984A/zh
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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CN2013101587615A 2006-02-14 2007-02-14 结合mcp-1的核酸 Pending CN103275984A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP06002935.2 2006-02-14
EP06002935 2006-02-14
EP06024202 2006-11-22
EP06024202.1 2006-11-22

Related Parent Applications (1)

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CN2007800113050A Division CN101415825B (zh) 2006-02-14 2007-02-14 结合mcp-1的核酸

Publications (1)

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CN103275984A true CN103275984A (zh) 2013-09-04

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CN2013101587615A Pending CN103275984A (zh) 2006-02-14 2007-02-14 结合mcp-1的核酸
CN2007800113050A Active CN101415825B (zh) 2006-02-14 2007-02-14 结合mcp-1的核酸

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US (4) US8193159B2 (enExample)
EP (3) EP2365080B1 (enExample)
JP (1) JP5537812B2 (enExample)
KR (2) KR101572893B1 (enExample)
CN (2) CN103275984A (enExample)
AT (1) ATE510014T1 (enExample)
AU (1) AU2007214668B2 (enExample)
BR (1) BRPI0707842B8 (enExample)
CA (1) CA2638847C (enExample)
DK (1) DK2135949T3 (enExample)
ES (1) ES2397803T3 (enExample)
MX (2) MX351107B (enExample)
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PT (1) PT2135949E (enExample)
RU (1) RU2518330C2 (enExample)
WO (1) WO2007093409A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2638847C (en) 2006-02-14 2016-08-09 Noxxon Pharma Ag Mcp-1 binding nucleic acids
US8367629B2 (en) * 2006-02-14 2013-02-05 Noxxon Pharma Ag MCP-1 binding nucleic acids and use thereof
GB0718167D0 (en) 2007-09-18 2007-10-31 Cancer Rec Tech Ltd Cancer marker and therapeutic target
WO2009068318A1 (en) * 2007-11-30 2009-06-04 Noxxon Pharma Ag Mcp-i binding nucleic acids and use thereof
US8710021B2 (en) * 2008-06-11 2014-04-29 Bionucleon S.R.L. Inhibition of HRP-3 using modified oligonucleotides
WO2010070394A1 (en) * 2008-12-17 2010-06-24 Universite Pierre Et Marie Curie-Paris Vi Modulators of the cx3cr1 receptor and therapeutic uses thereof
WO2012025251A1 (en) * 2010-08-27 2012-03-01 Noxxon Pharma Ag Nucleic acids for treatment of chronic complications of diabetes
US8465413B2 (en) 2010-11-25 2013-06-18 Coloplast A/S Method of treating Peyronie's disease
CN104661664B (zh) 2012-07-13 2020-07-03 波涛生命科学有限公司 手性控制
JP2017502075A (ja) 2013-11-04 2017-01-19 ノクソン ファーマ エージー 腎障害治療の手段および方法
WO2021178923A1 (en) 2020-03-06 2021-09-10 Drinksavvy, Inc. Devices and methods for detecting a target analyte of interest
WO2023154452A1 (en) 2022-02-11 2023-08-17 Waypoint Bio, Inc. Cellular staining probes for analyte detection

Family Cites Families (13)

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Publication number Priority date Publication date Assignee Title
US6011020A (en) 1990-06-11 2000-01-04 Nexstar Pharmaceuticals, Inc. Nucleic acid ligand complexes
US6670321B1 (en) * 1998-12-30 2003-12-30 The Children's Medical Center Corporation Prevention and treatment for retinal ischemia and edema
EP1306382A1 (de) 2001-10-26 2003-05-02 Noxxon Pharma AG Modifizierte L-Nukleinsäure
ES2346640T4 (es) * 2001-10-26 2011-04-26 Noxxon Pharma Ag Ácido l-nucleico modificado.
EP1386972A1 (en) 2002-08-01 2004-02-04 Noxxon Pharma AG Method and apparatus for designing a nucleic acid having a desired property
AU2003251681A1 (en) * 2002-08-01 2004-02-23 Noxxon Pharma Ag Ghrelin binding nucleic acids
US20090281296A1 (en) 2004-02-09 2009-11-12 Supramol Parenteral Colloid Gmbh Process for the production of conjugates from polysaccharides and polynucelotides
US20060030535A1 (en) * 2004-03-05 2006-02-09 Healy Judith M Controlled modulation of the pharmacokinetics and biodistribution of aptamer therapeutics
WO2005108431A1 (en) * 2004-05-04 2005-11-17 University Of Kentucky Research Foundation Methods and compositions for the treatment of ocular neovascularization
US8367629B2 (en) * 2006-02-14 2013-02-05 Noxxon Pharma Ag MCP-1 binding nucleic acids and use thereof
CA2638847C (en) 2006-02-14 2016-08-09 Noxxon Pharma Ag Mcp-1 binding nucleic acids
KR101589442B1 (ko) * 2007-08-06 2016-02-01 녹손 파르마 아게 에스디에프-1 결합형 핵산 및 이의 용도
WO2009068318A1 (en) 2007-11-30 2009-06-04 Noxxon Pharma Ag Mcp-i binding nucleic acids and use thereof

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EP2135949A1 (en) 2009-12-23
WO2007093409A3 (en) 2007-12-13
DK2135949T3 (da) 2013-02-04
EP2135949B1 (en) 2012-10-17
WO2007093409A2 (en) 2007-08-23
KR20130100213A (ko) 2013-09-09
US20160208262A1 (en) 2016-07-21
BRPI0707842B1 (pt) 2021-09-21
ES2397803T3 (es) 2013-03-11
JP2009526532A (ja) 2009-07-23
EP1984501A2 (en) 2008-10-29
KR101475865B1 (ko) 2015-01-02
WO2007093409A8 (en) 2011-01-20
US10273480B2 (en) 2019-04-30
US9670491B2 (en) 2017-06-06
KR20080105078A (ko) 2008-12-03
BRPI0707842A2 (pt) 2011-05-10
MX337801B (es) 2016-03-18
KR101572893B1 (ko) 2015-12-02
CN101415825B (zh) 2013-05-08
EP1984501B1 (en) 2011-05-18
CN101415825A (zh) 2009-04-22
RU2518330C2 (ru) 2014-06-10
HK1129127A1 (en) 2009-11-20
CA2638847C (en) 2016-08-09
US20180066265A1 (en) 2018-03-08
AU2007214668B2 (en) 2012-05-24
EP2365080B1 (en) 2016-04-13
RU2008136907A (ru) 2010-03-20
PL2135949T3 (pl) 2013-03-29
ATE510014T1 (de) 2011-06-15
US20100284961A1 (en) 2010-11-11
CA2638847A1 (en) 2007-08-23
MX351107B (es) 2017-10-02
AU2007214668A1 (en) 2007-08-23
EP2365080A1 (en) 2011-09-14
PT2135949E (pt) 2013-01-07
BRPI0707842B8 (pt) 2023-04-18
US8193159B2 (en) 2012-06-05
US8691784B2 (en) 2014-04-08
US20130035376A1 (en) 2013-02-07
JP5537812B2 (ja) 2014-07-02

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Application publication date: 20130904