CN103272144A - Medicine for treating polycystic ovarian syndrome - Google Patents

Medicine for treating polycystic ovarian syndrome Download PDF

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CN103272144A
CN103272144A CN2013101973297A CN201310197329A CN103272144A CN 103272144 A CN103272144 A CN 103272144A CN 2013101973297 A CN2013101973297 A CN 2013101973297A CN 201310197329 A CN201310197329 A CN 201310197329A CN 103272144 A CN103272144 A CN 103272144A
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semen
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radix
rhizoma
colla
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CN103272144B (en
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孙炳云
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Abstract

The invention provides a medicine for treating polycystic ovarian syndrome, which is quick to take effect, good in effect and free from toxic and side effects. The medicine for treating polycystic ovarian syndrome comprises the following components by weight: 10-20g of Semen Cuscutae, 8-18g of semen plantaginis, 10-20g of Eucommia ulmoides, 8-20g of radix rehmanniae preparata, 10-30g of Angelica sinensis, 6-12g of peach kernel, 12-18g of raw semen coicis, 10-16g of Ligusticum wallichii, 10-20g of Morinda officinalis, 3-10g of placenta hominis, 8-22g of deer-horn glue, 8-22g of tortoise-plastron glue, 5-18g of Poria cocos, 10-30g of Chinese yam, 5-15g of medlar, 5-15g of Codonopsis pilosula, 8-16g of rhizoma acori graminei, 10-30g of ovateleaf holly bark, 30-60g of leonurus, 8-12g of ground beeltle, 6-12g of szechwan Chinaberry fruit, 10-18g of seaweed and 10-18g of long-stalked kadsura.

Description

A kind of medicine for the treatment of polycystic ovary syndrome
Technical field
The present invention relates to Chinese medicine gynecological technical field, be specifically related to a kind of medicine for the treatment of polycystic ovary syndrome.
Background technology
Polycystic ovary syndrome has infrequent menstruation or amenorrhea, infertile, hirsutism and obesity, and bilateral ovaries is symptoms such as capsule increase.
The definite cause of disease of polycystic ovarian syndrome is not quite clear, thinks that at present ovary produces too much androgen, and androgenic excessive generation is because the interior synergistic result of multiple hormonal system dysfunction of body.Polycystic ovarian syndrome is one of infertile principal element of young married woman.Be by the not normal a kind of syndrome that produces of menstrual regulation, this class patient has infrequent menstruation or amenorrhea, infertile, hirsutism and obesity, and bilateral ovaries is the capsule increase.
For this disease, doctor trained in Western medicine generally adopts three-step approach: the ovary to cystic hyperplasia is done wedge excision; Drug therapy adopts and reaches English, Marvelon etc., and pregnancy rate is low, abortion ratio is high; Follicle is punctured, easily ovary is caused damage, or cause pelvic adhesion and fetus is had harm.
Summary of the invention
The object of the invention provides the medicine of a kind of instant effect, effective, the treatment polycystic ovary syndrome that has no side effect.
To achieve these goals, the present invention is by the following technical solutions:
A kind of medicine for the treatment of polycystic ovary syndrome, it is made up of following weight raw material medicine components in proportion: Semen Cuscutae 10-20g, Semen Plantaginis 8-18g, Cortex Eucommiae 10-20, Radix Rehmanniae Preparata 8-20g, Radix Angelicae Sinensis 10-30g, Semen Persicae 6-12 g, Semen Coicis 12-18 g, Rhizoma Chuanxiong 10-16 g, Radix Morindae Officinalis 10-20 g, Placenta Hominis 3-10g, Colla cornus cervi 8-22 g, Colla Plastri Testudinis 8-22 g, Poria 5-18g, Rhizoma Dioscoreae 10-30g, Fructus Lycii 5-15 g, Radix Codonopsis 5-15 g, Rhizoma Acori Graminei 8-16 g, cross mountain breeze 10-30 g, Herba Leonuri 30-60g, Eupolyphaga Seu Steleophaga 8-12g, Fructus Toosendan 6-12g, Sargassum 10-18g, Caulis Kadsurae Longipedunculatae 10-18g.
The medicine of above-mentioned treatment polycystic ovary syndrome, it is made up of following weight raw material medicine components in proportion: Semen Cuscutae 15 g, Semen Plantaginis 15 g, the Cortex Eucommiae 15 g, Radix Rehmanniae Preparata 10g, Radix Angelicae Sinensis 15g, Semen Persicae 10 g, Semen Coicis 15 g, Rhizoma Chuanxiong 15 g, Radix Morindae Officinalis 15 g, Placenta Hominis 5g, Colla cornus cervi 15 g, Colla Plastri Testudinis 15 g, Poria 15g, Rhizoma Dioscoreae 30g, Fructus Lycii 10 g, Radix Codonopsis 10 g, Rhizoma Acori Graminei 12 g, mistake mountain breeze 30, Herba Leonuri 60 g, Eupolyphaga Seu Steleophaga 10 g, Fructus Toosendan 10 g, Sargassum 15 g, Caulis Kadsurae Longipedunculatae 15 g.
A kind of preparation method for the treatment of the medicine of polycystic ovary syndrome, said ratio takes by weighing the crude drug except Placenta Hominis, Colla cornus cervi, Colla Plastri Testudinis, places in the marmite, adds water 1000ml and soaks crude drug, soaks 90 minutes, and little fire decocts 30 minutes, and filtration takes concoction; Add water 800ml again, little fire decocts 25 minutes, and filtration takes concoction; Colla cornus cervi, Colla Plastri Testudinis grind to form smalls, then Placenta Hominis, Colla cornus cervi and Colla Plastri Testudinis and twice medicine juice mixing are got final product.
Instructions of taking: morning and evening twice decoction being taken warmly.
The present invention is made up of pure Chinese medicine, and the effect of each Chinese medicine is as follows:
Semen Cuscutae: sweet, temperature is returned the liver,kidney,spleen warp.Nourishing the liver and kidney, the controlling nocturnal emission with astringent drugs reducing urination, antiabortive, make eye bright antidiarrheal.Be used for impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen is suffered from a deficiency of the kidney and is rushed down; Externally treating leucoderma.
Semen Plantaginis: sweet, cold.Return kidney, liver, lung meridian.Inducing diuresis for treating stranguria syndrome, eliminating dampness by diuresis antidiarrheal, liver heat removing and eyesight improving, removing heat from the lung and dissipating phlegm.Cure mainly edema, stranguria, diarrhea due to summer heat and dampness, the puckery pain of conjunctival congestion, order is secretly dim-sighted, phlegm-heat cough; Essential hypertension.
The Cortex Eucommiae: invigorating the liver and kidney, bone and muscle strengthening, antiabortive.Be used for that lumbago due to renal deficiency, muscles and bones are unable, blood leaking in gestation, frequent fetal movement, hypertension etc.
Radix Rehmanniae Preparata: sweet, tepor.Return liver, kidney channel.The yin nourishing of enriching blood, life essence-filling, marrow-benefitting.
Radix Angelicae Sinensis: flavor Wen Ganxin.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
Semen Persicae: bitter sweet, flat.Go into the heart, liver, large intestine channel.Blood stasis removing and clots absorbing is moisturized laxation.Control amenorrhea , mass in the abdomen, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.
Semen Coicis: sweet in the mouth is slightly cold.Go into lung, spleen, liver, stomach, large intestine.Spleen invigorating, tonifying the lung, heat clearing away, dampness removing.Control and have loose bowels, arthralgia chiefly caused by damp pathogen, the contracture of muscle arteries and veins, joint stuffiness, edema, beriberi, consumptive lung disease, lung abscess, acute appendicitis, stranguria with turbid discharge, leucorrhea.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.Blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping.
Radix Morindae Officinalis: suffering, sweet, slightly warm in nature.Return kidney, Liver Channel.Reinforcing the kidney and supporting YANG, expelling wind and removing dampness, strengthening the tendons and bones.Cure mainly that impotence and seminal emission, cold womb are infertile, menoxenia, few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity be soft.
Placenta Hominis: warm, sweet, salty; GUIXIN, lung, kidney channel.The kidney warming is mended smart, benefiting QI and nourishing blood.It is thin to be used for the chronic consumptive disease win, hectic fever due to YIN-deficiency night sweat, and cough and asthma, lack of appetite is breathed hard, impotence and seminal emission, infertile hypogalactia.
Colla cornus cervi: temperature compensation Liver and kidney, beneficial intensive culture blood.Be used for the blood deficiency dizziness, the acid of waist knee joint is cold, and asthenia is become thin.
Colla Plastri Testudinis: YIN nourishing, enrich blood hemostasis.Control deficiency of YIN anemia, the consumptive fever hectic fever due to YIN-deficiency is spitted blood, epistaxis, dysphoria with smothery sensation palpitation with fear, lumbago due to renal deficiency, flaccidity of feet and knees, metrorrhagia, leukorrhagia.
Poria: sweet, light, flat.GUIXIN warp, lung meridian, spleen channel, kidney channel.Function: diuretic medicine; Diuretics with the action of eliminating dampness.Modern medicine study: Poria energy enhancing human body immunity function, pachyman has tangible antitumor and protects the liver dirty effect.
Rhizoma Dioscoreae: sweet in the mouth, property is flat.Return spleen, lung, kidney channel.The spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.Be used for insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.
Cross mountain breeze: nature and flavor are bitter, belong to coldly, have hemostasis and the smoothly effect of skin.
Fructus Lycii, the treating the liver kidney yin is lost, replenishing vital essence to improve eyesight.Be used for the asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, impotence and seminal emission, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear.
Radix Codonopsis: have invigorating the spleen and replenishing QI, the effect of spleen invigorating lung benefiting.Modern study, Radix Codonopsis contain various saccharides, phenols, sterol, volatile oil, scutellarein glucosid, Saponin and micro-alkaloid, have effects such as enhancing immunity, blood vessel dilating, blood pressure lowering, microcirculation improvement, enhancing hemopoietic function.
Rhizoma Acori Graminei: acrid in the mouth, hardship, slightly warm in nature.GUIXIN, liver, spleen channel.The removing dampness appetizing, the eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.It is not hungry to be used for the gastral cavity painful abdominal mass, mouthful dysentery of keeping silent, coma epilepsy, forgetful deafness.Regulate the flow of vital energy, invigorate blood circulation, the wind that looses dries.Control epilepsy, syncope due to accumulation of phlegm, the calentura coma, forgetful, deafness with qi stagnation, ambition unhappiness, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury.
Herba Leonuri: invigorate blood circulation, blood stasis dispelling, regulating menstruation, water disappears.Control menoxenia, the vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria is rushed down blood, the carbuncle skin infection.
Eupolyphaga Seu Steleophaga: salty, cold; Slightly poisonous.Return Liver Channel.Removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.Be used for the muscles and bones folding and hinder blood stasis amenorrhea, lump in the abdomen mass in the abdomen.
Fructus Toosendan: hardship, cold, poisonous.Go into liver, stomach, small intestine meridian.Except damp and hot, clearing away liver-fire, pain relieving, parasite killing.Control epigastric pain with cold limbs due to adverseness of heat, hypochondriac pain, colic, abdominal pain due to worm stagnation.
Sargassum: bitter in the mouth, salty, cold, return liver stomach warp.Softening the hard mass, expectorant, diuretic, detumescent.Cure mainly thyromegaly, a submental lymph nodes tuberculosis.Eliminating stagnation gas carbuncle, abdomen inner product piece, distending pain, the ring of abdomen hollow.
Caulis Kadsurae Longipedunculatae: sour in the mouth, warm in nature, return liver, lung, stomach warp.Relaxing muscles and tendons to promote blood circulation, regulating QI to relieve pain, strengthening the spleen to promote digestion is astringed the lung and is promoted the production of body fluid.Cure mainly menoxenia, bed-wetting, food stagnation stagnation.
Clinical efficacy is summed up
One, physical data: patient's 96 examples, all cases meet the diagnosis of polycystic ovary syndrome, age 23-42 year, average 30.7 years old.
Two, diagnostic criteria:
(1) clinical manifestation:
The patient has in the following symptom one or more: 1) menoxenia: infrequent menstruation, very few before the amenorrhea, amenorrhea, minority ischemia or inadequate luteal function.2) hirsutism: chaeta, pubes are dense.3) obesity: moderate obesity.4) infertile: due to the anovulation.
(2) sign: detect abnormal uterine, bilateral ovaries increases.
(3) B ultrasonic detects: typical person can show the polycystic ovary image of a plurality of follicles that bilateral ovaries increases.
Three, method of administration: Placenta Hominis, Colla cornus cervi and Colla Plastri Testudinis and twice medicine juice mix and divide twice decoction being taken warmly sooner or later.
Four, curative effect determinate standard:
Cure: menstrual cycle is normal, and hormonal readiness is measured normal, and B ultrasonic detects normal ovulation, and many capsules of B ultrasonic ovary sex character resembles disappearance;
Effectively: menstrual cycle is normal substantially, and hormonal readiness is measured LH/FSH ratio and reduced, and T value reduces, and B ultrasonic detects have superiority ovarian follicular growth but anovulation, and the property minimizing of many capsules of B ultrasonic ovary or single the survey disappear.
Invalid: clinical symptoms does not have improvement, and hormonal readiness is measured not have and changed, and B ultrasonic detects no dominant follicle growth, and many capsules of B ultrasonic ovary sex character resembles no change.
Five, therapeutic effect:
Figure 2013101973297100002DEST_PATH_IMAGE001
Six, model case:
1, granddaughter scholar, 28 years old, 15 the beginning of the year tide, menstruation is consistent to be to come about half a year once, detects through B ultrasonic: bilateral ovaries increases, in many folliculi ovarici vesiculosis are arranged, be diagnosed as: polycystic ovary syndrome.Take the embodiment of the invention 1 medicine, taking two months continuously is a course for the treatment of, after taking a course for the treatment of, menstruation is arrived, and menstrual cycle is normal substantially, and bilateral ovaries obviously reduces, many capsules of minority follicle is still arranged, after take two courses for the treatment of continuously, many capsules of B ultrasonic ovary sex character resembles disappearance, becomes pregnant successfully in the second month after the drug withdrawal.
2, Mrs Li, 35 years old, bodily form obesity, lip hair, shank-feathering are many and grow, and B ultrasonic is diagnosed as polycystic ovary syndrome.Take medicine of the present invention, take 3 courses for the treatment of continuously, check that all are normal, became pregnant successfully in six month after the drug withdrawal.
3, Mrs Jiang, 32 years old, did medicine stream after, menstruation is undesired, takes behind the Progesterone in the periodly, menstrual blood volume is few, menolipsis after the drug withdrawal.Gynecologial examination uterus and adnexa are normal, and six inspection: LH/FSH of gonadal hormone are greater than the low value of 3, E2 near reference value.B ultrasonic detects in two ovaries all the no echo area, is diagnosed as: polycystic ovary syndrome.Take medicine of the present invention, take 2 courses for the treatment of continuously, check that all are normal, became pregnant successfully in five month after the drug withdrawal.
Beneficial effect of the present invention:
Effect with blood circulation promoting and blood stasis dispelling, warming and recuperating the kidney-YANG, preparation is simple, has no side effect, and good effect can be treated the polycystic ovary syndrome patient.
The specific embodiment
Below in conjunction with specific embodiment the present invention is described in further details, following explanation only is exemplary, does not limit protection scope of the present invention.
Embodiment 1
A kind of medicine for the treatment of polycystic ovary syndrome is characterized in that: it is made up of following weight raw material medicine components in proportion: Semen Cuscutae 10g, Semen Plantaginis 18g, the Cortex Eucommiae 10, Radix Rehmanniae Preparata 20g, Radix Angelicae Sinensis 10g, Semen Persicae 6g, Semen Coicis 12g, Rhizoma Chuanxiong 16 g, Radix Morindae Officinalis 10g, Placenta Hominis 10g, Colla cornus cervi 8g, Colla Plastri Testudinis 22 g, Poria 5g, Rhizoma Dioscoreae 10g, Fructus Lycii 15 g, Radix Codonopsis 15 g, Rhizoma Acori Graminei 16 g, mistake mountain breeze 10g, Herba Leonuri 45g, Eupolyphaga Seu Steleophaga 8g, Fructus Toosendan 12 g, Sargassum 10g, Caulis Kadsurae Longipedunculatae 10g.
Said ratio takes by weighing the crude drug except Placenta Hominis, Colla cornus cervi, Colla Plastri Testudinis, places in the marmite, adds water 1000ml and soaks crude drug, soaks 90 minutes, and little fire decocts 30 minutes, and filtration takes concoction; Add water 800ml again, little fire decocts 25 minutes, and filtration takes concoction; Colla cornus cervi, Colla Plastri Testudinis grind to form smalls, then Placenta Hominis, Colla cornus cervi and Colla Plastri Testudinis and twice medicine juice mixing are got final product, and divide twice decoction being taken warmly sooner or later.
Embodiment 2
A kind of medicine for the treatment of polycystic ovary syndrome, it is made up of following weight raw material medicine components in proportion: Semen Cuscutae 15 g, Semen Plantaginis 15 g, the Cortex Eucommiae 15 g, Radix Rehmanniae Preparata 10g, Radix Angelicae Sinensis 15g, Semen Persicae 10 g, Semen Coicis 15 g, Rhizoma Chuanxiong 15 g, Radix Morindae Officinalis 15 g, Placenta Hominis 5g, Colla cornus cervi 15 g, Colla Plastri Testudinis 15 g, Poria 15g, Rhizoma Dioscoreae 30g, Fructus Lycii 10 g, Radix Codonopsis 10 g, Rhizoma Acori Graminei 12 g, mistake mountain breeze 30, Herba Leonuri 60 g, Eupolyphaga Seu Steleophaga 10 g, Fructus Toosendan 10 g, Sargassum 15 g, Caulis Kadsurae Longipedunculatae 15 g.
Preparation and instructions of taking are with embodiment 1.
Embodiment 3
A kind of medicine for the treatment of polycystic ovary syndrome is characterized in that: it is made up of following weight raw material medicine components in proportion: Semen Cuscutae 20g, Semen Plantaginis 8g, the Cortex Eucommiae 20, Radix Rehmanniae Preparata 8g, Radix Angelicae Sinensis 30g, Semen Persicae 12 g, Semen Coicis 18 g, Rhizoma Chuanxiong 10g, Radix Morindae Officinalis 20 g, Placenta Hominis 3g, Colla cornus cervi 22g, Colla Plastri Testudinis 8g, Poria 18g, Rhizoma Dioscoreae 20g, Fructus Lycii 5g, Radix Codonopsis 5g, Rhizoma Acori Graminei 8g, mistake mountain breeze 20 g, Herba Leonuri 30g, Eupolyphaga Seu Steleophaga 12 g, Fructus Toosendan 6g, Sargassum 18 g, Caulis Kadsurae Longipedunculatae 18g.
Preparation and instructions of taking are with embodiment 1.
Though the present invention has been described in detail and has quoted some specific embodiments as proof, concerning those skilled in the art, only otherwise leave the spirit and scope of the present invention can to do various improvement be apparent.

Claims (2)

1. medicine for the treatment of polycystic ovary syndrome, it is characterized in that: it is made up of following weight raw material medicine components in proportion: Semen Cuscutae 10-20g, Semen Plantaginis 8-18g, Cortex Eucommiae 10-20, Radix Rehmanniae Preparata 8-20g, Radix Angelicae Sinensis 10-30g, Semen Persicae 6-12 g, Semen Coicis 12-18 g, Rhizoma Chuanxiong 10-16 g, Radix Morindae Officinalis 10-20 g, Placenta Hominis 3-10g, Colla cornus cervi 8-22 g, Colla Plastri Testudinis 8-22 g, Poria 5-18g, Rhizoma Dioscoreae 10-30g, Fructus Lycii 5-15g, Radix Codonopsis 5-15g, Rhizoma Acori Graminei 8-16g, cross mountain breeze 10-30g, Herba Leonuri 30-60g, Eupolyphaga Seu Steleophaga 8-12g, Fructus Toosendan 6-12g, Sargassum 10-18g, Caulis Kadsurae Longipedunculatae 10-18g.
2. according to the medicine of the described treatment polycystic ovary syndrome of claim 1, it is characterized in that: it is made up of following weight raw material medicine components in proportion: Semen Cuscutae 15 g, Semen Plantaginis 15 g, the Cortex Eucommiae 15 g, Radix Rehmanniae Preparata 10g, Radix Angelicae Sinensis 15g, Semen Persicae 10 g, Semen Coicis 15 g, Rhizoma Chuanxiong 15 g, Radix Morindae Officinalis 15 g, Placenta Hominis 5g, Colla cornus cervi 15 g, Colla Plastri Testudinis 15 g, Poria 15g, Rhizoma Dioscoreae 30g, Fructus Lycii 10 g, Radix Codonopsis 10 g, Rhizoma Acori Graminei 12 g, mistake mountain breeze 30, Herba Leonuri 60 g, Eupolyphaga Seu Steleophaga 10 g, Fructus Toosendan 10 g, Sargassum 15 g, Caulis Kadsurae Longipedunculatae 15 g.
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CN104707023A (en) * 2013-12-17 2015-06-17 北京因科瑞斯医药科技有限公司 Traditional Chinese medicinal composition for treating polycystic ovary syndrome, and preparation method thereof
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CN105148221A (en) * 2015-08-27 2015-12-16 张凌云 Traditional Chinese medicine preparation for treating polycystic ovarian syndrome and preparing method thereof
CN105214005A (en) * 2015-11-11 2016-01-06 葛淑文 The oral Chinese medicine powder for the treatment of polycystic ovary syndrome
CN105214005B (en) * 2015-11-11 2018-11-23 葛淑文 The oral traditional Chinese medicine powder for treating polycystic ovary syndrome
CN105535466A (en) * 2016-01-25 2016-05-04 青岛云天生物技术有限公司 Pharmaceutical composition for treating pubescent polycystic ovarian syndrome
CN105535800A (en) * 2016-02-29 2016-05-04 陈远征 Medicine composition for treating polycystic ovarian syndrome recurrent abortion
CN105688175A (en) * 2016-04-06 2016-06-22 杨春蕾 Traditional Chinese medicine preparation for treating polycystic ovarian syndrome
CN109464618A (en) * 2018-12-27 2019-03-15 同溢堂药业有限公司 A kind of drug and preparation method thereof for treating Stein-Leventhal syndrome

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