CN103260637B - 乙酰肝素n-硫酸酯酶cns递送的方法和组合物 - Google Patents

乙酰肝素n-硫酸酯酶cns递送的方法和组合物 Download PDF

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CN103260637B
CN103260637B CN201180040902.2A CN201180040902A CN103260637B CN 103260637 B CN103260637 B CN 103260637B CN 201180040902 A CN201180040902 A CN 201180040902A CN 103260637 B CN103260637 B CN 103260637B
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concentration
purposes
hns
protein
stabilization formulations
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CN103260637A (zh
Inventor
F·纳托里
G·朱
J·特略
Y·江
J·宗
Z·夏若克
B·维纳格利亚
J·潘
R·菲佛
P·加莱斯
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Shire Human Genetics Therapies Inc
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Shire Human Genetics Therapies Inc
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
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    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
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    • C12Y310/01001—N-Sulfoglucosamine sulfohydrolase (3.10.1.1)
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CN201180040902.2A 2010-06-25 2011-06-25 乙酰肝素n-硫酸酯酶cns递送的方法和组合物 Expired - Fee Related CN103260637B (zh)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US35885710P 2010-06-25 2010-06-25
US61/358,857 2010-06-25
US36078610P 2010-07-01 2010-07-01
US61/360,786 2010-07-01
US38786210P 2010-09-29 2010-09-29
US61/387,862 2010-09-29
US201161435710P 2011-01-24 2011-01-24
US61/435,710 2011-01-24
US201161442115P 2011-02-11 2011-02-11
US61/442,115 2011-02-11
US201161476210P 2011-04-15 2011-04-15
US61/476,210 2011-04-15
US201161495268P 2011-06-09 2011-06-09
US61/495,268 2011-06-09
PCT/US2011/041922 WO2011163647A2 (en) 2010-06-25 2011-06-25 Methods and compositions for cns delivery of heparan n-sulfatase

Related Child Applications (1)

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CN201610086722.2A Division CN105664142A (zh) 2010-06-25 2011-06-25 乙酰肝素n-硫酸酯酶cns递送的方法和组合物

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CN103260637A CN103260637A (zh) 2013-08-21
CN103260637B true CN103260637B (zh) 2016-04-06

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US (1) US9320711B2 (enExample)
EP (1) EP2588131B1 (enExample)
JP (1) JP6073783B2 (enExample)
KR (1) KR20140005842A (enExample)
CN (1) CN103260637B (enExample)
AU (2) AU2011270667B2 (enExample)
BR (1) BR112012033197A2 (enExample)
CA (1) CA2805413A1 (enExample)
MX (1) MX2013000320A (enExample)
NZ (1) NZ605874A (enExample)
RU (1) RU2012154576A (enExample)
TW (1) TWI546078B (enExample)
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