CN103251913A - Traditional Chinese medicine composition for protecting gastrointestinal tract of livestock and preparation method thereof - Google Patents
Traditional Chinese medicine composition for protecting gastrointestinal tract of livestock and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for protecting the gastrointestinal tract of livestock and a preparation method thereof. The traditional Chinese medicine composition comprises the raw material medicines in parts by weight: 5-10 parts of rhizoma zingiberis, 5-20 parts of Rhizoma Atractylodis Macrocephalae, 5-10 parts of malt, 1-8 parts of elecampane, 5-15 parts of rheum officinale charcoal and 1-5 parts of Coptis chinensis stigma. The preparation method comprises soup decocting step, soup concentrating step and microbial fermenting step. The composition provided by the invention has the beneficial effects that the raw material medicines are organically combined to synergistically condition physique of livestock so as to exert the functions of the raw material medicines to the maximum extent, so that the gastrointestinal tract of livestock is effectively protected, and the composition is free from any side effects to other organs of livestock and does not damage other organs.
Description
Technical field
The present invention relates to a kind of poultry herbal medicine, be particularly related to the gastrointestinal tract of livestock and fowls dysfunction that a kind of prevention and treatment cause owing to reasons such as feedstuff and drinking water quality, cause pathogeny imcrobe infection and Drug abuse, and then cause Chinese medicine composition of various gastrointestinal problems and preparation method thereof.
Background technology
Because the height of gastrointestinal tract of livestock and fowls opening property, the variation of external environment and animal body self homeostasis all can change the 26S Proteasome Structure and Function of intestinal, and then causes all kinds of gastroenteropathys.Mainly show as various diarrhoea dysentery, proventriculitis, intestinal bleeding etc.The influence that following several respects produce in numerous influence factors is the most remarkable: the one, and the quality of feedstuff and drinking-water, feedstuff and drinking water are the main causes that the overwhelming majority causes gastrointestinal problems, off qualityly will cause many-sided influence; The 2nd, cause pathogeny imcrobe infection, a large amount of pathogenic microorganisms can damage the epithelial integrity of intestinal mucosa, suppresses the growth of probiotics simultaneously, causes the normal flora structural imbalance of intestinal; The 3rd, the abuse antibacterials because medicine to the non-selective effect of probiotics and harmful bacterium, has also been killed a large amount of probioticss when eliminating harmful bacterium, have caused the generation of medicine dysbacteriosis.In addition, under stressed condition, gastrointestinal is digested and assimilated with gut barrier protection also can produce huge change.The gastrointestinal tract of livestock and fowls disease can produce a series of problem, as: poultry digest and assimilate the nutrient substance ability and reduce, body intestinal mucosa immunologic function degression, microorganism species imbalance and plant's microorganism disorder, efficiency of feed utilization descends, even cause various septicemia and death, bring enormous economic loss to the raiser.
Development along with the intensive culture industry, Western medicine has shown degradation series of malpractice under drug residue, bacterial drug resistance increase, the antibiotic action effect gradually, and the digestive tract problem is more and more serious in recent years, diarrhoea, feed conversion rate hang down in the Production of Livestock and Poultry process more and more general, and conventional medicament can not fundamentally address this problem.Little ecology mainly is the colony balance that improves in the digestive tract, can not improve the digestive tract function, and treatment does not have obviously effect to the digestion organ dysfunction, is adopting antibiotic to carry out symptomatic treatment aspect the treatment gastroenteropathy in the market more.The life-time service of antibiotic on livestock and poultry breeding industry not only increases medical expense, is difficult to control higher mortality rate, and presented following drawback: make pathogen generation drug resistance and reduce its effect; Suppress the beneficial microbe in the animal body, caused the superinfection of disease; Produce drug residue, and then harm humans health etc.
Summary of the invention
Technical problem to be solved by this invention is that the treatment primary disease has microbial ecological agent and antibiotic Western medicine; Little ecology mainly is the colony balance that improves in the digestive tract, can not improve the digestive tract function, and treatment does not have obviously effect to the digestion organ dysfunction.And Western medicine has shown degradation series of malpractice under drug residue, bacterial drug resistance increase, the antibiotic action effect gradually, conventional medicament can not fundamentally solve in the Production of Livestock and Poultry process problems such as livestock and poultry diarrhea, feed conversion rate be low, but the Chinese patent medicine that does not have specially good effect
In order to solve the problems of the technologies described above; the invention provides that a kind of side effect is little, outstanding effect is for the protection of the Chinese medicine composition of gastrointestinal tract of livestock and fowls, described Chinese medicine composition comprises the raw medicinal material of following ratio of weight and number: 5 ~ 15 parts of 5 ~ 10 parts of Rhizoma Zingiberiss, 5 ~ 20 parts of the Rhizoma Atractylodis Macrocephalaes, 5 ~ 10 parts in Fructus Hordei Germinatus, 1 ~ 8 part of the Radix Aucklandiae and charred Radix Et Rhizoma Rheis.
Also comprise Rhizoma Coptidis in the described Chinese medicine composition, described Chinese medicine composition comprises the raw medicinal material of following ratio of weight and number: 1 ~ 5 part of 5 ~ 15 parts of 5 ~ 10 parts of Rhizoma Zingiberiss, 5 ~ 20 parts of the Rhizoma Atractylodis Macrocephalaes, 5 ~ 10 parts in Fructus Hordei Germinatus, 1 ~ 8 part of the Radix Aucklandiae, charred Radix Et Rhizoma Rhei and Rhizoma Coptidis.
Each raw medicinal material and ratio of weight and number thereof are preferably in the described Chinese medicine composition: 1 part of 5 parts of Rhizoma Zingiberiss, 5 parts of the Rhizoma Atractylodis Macrocephalaes, 5 parts in Fructus Hordei Germinatus, 1 part of the Radix Aucklandiae, 5 parts of charred Radix Et Rhizoma Rheis and Rhizoma Coptidis.
Each raw medicinal material and ratio of weight and number thereof can also be preferably in the described Chinese medicine composition: 5 parts of 10 parts of Rhizoma Zingiberiss, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts in Fructus Hordei Germinatus, 8 parts of the Radix Aucklandiae, 15 parts of charred Radix Et Rhizoma Rheis and Rhizoma Coptidis.
Each raw medicinal material and ratio of weight and number thereof can be preferably again in the described Chinese medicine composition: 3 parts of 7.5 parts of Rhizoma Zingiberiss, 12.5 parts of the Rhizoma Atractylodis Macrocephalaes, 7.5 parts in Fructus Hordei Germinatus, 4.5 parts of the Radix Aucklandiae, 10 parts of charred Radix Et Rhizoma Rheis and Rhizoma Coptidis.
In order better to realize that foregoing invention purpose, the present invention also provide a kind of preparation method of the Chinese medicine composition for the protection of gastrointestinal tract of livestock and fowls, preparation method may further comprise the steps:
(1) decocts the medicinal liquid step: each raw medicinal material is mixed by weight ratio, decoct, obtain decocting medicinal liquid after the filtration;
(2) concentrated medicament step: the decoction medicinal liquid that obtains in the described decoction medicinal liquid step is concentrated, obtain concentrated medicament;
(3) microbial fermentation step: the concentrated medicament that obtains in the described concentrated medicament step is adopted microbial fermentation, can make described Chinese medicine composition.
Wherein, described decoction medicinal liquid step comprises: each raw medicinal material is mixed by weight ratio, be positioned in the Chinese medicine extraction jar, add water and under 20～40 ℃ of warm water, soaked 2～4 hours by 8～10 times of amounts of Chinese medicine gross weight, heat then to 100 ℃ of decoctions 1～3 hour, filter, obtain decocting medicinal liquid.
Described decoction medicinal liquid step is preferably: each raw medicinal material is mixed by weight ratio, be positioned in the Chinese medicine extraction jar, add water and under 20～40 ℃ of warm water, soaked 2～4 hours by 8～10 times of amounts of raw medicinal material gross weight, heat then to 100 ℃ of decoctions 1～3 hour, filter, obtain decocting for the first time medicinal liquid; 6～10 times of flow control secondaries by the raw medicinal material gross weight in holding the Chinese medicine extraction jar of medicinal residues add water, decoct 1～3 hour, filter, and obtain decocting medicinal liquid for the second time, will decoct medicinal liquid for the second time and decoct medicinal liquid with the first time and mix, and obtain decocting medicinal liquid.
Described concentrated medicament step comprises: with the decoction medicinal liquid that obtains in the described decoction medicinal liquid step adopt two imitate concentrators be-0.03 at pressure～-0.08MPa, temperature are to concentrate under 60～80 ℃ of conditions, be concentrated into that relative density is 1.09～1.15 under the room temperature, obtain concentrated medicament.
Described microbial fermentation step comprises: the concentrated medicament that described concentrated medicament step obtains is put into fermentation tank, in every 100L concentrated medicament, add sucrose 2.0～3.0kg, yeast powder 0.5～1.0 kg, diammonium hydrogen citrate 0.1～0.3 kg, magnesium sulfate 0.01～0.03 kg, potassium dihydrogen phosphate 0.3～0.6 kg and seed liquor 10～30ml, make the interior temperature of fermentation tank keep 32～40 ℃, the mixing speed of fermentation tank is 100～200r/h, ventilation is 1～4L/h, continuing fermentation 10～20h, the liquid that obtains is described Chinese medicine composition.
Described seed liquor comprises that quantity is that aspergillus niger and/or the quantity of 2 * 107～8 * 107/ml is the Bafillus natt of 2 * 107～8 * 107/ml.
The present invention also provides a kind of using method of protecting the Chinese medicine composition of gastrointestinal tract of livestock and fowls, when described Chinese medicine composition is used as prevention, in animal and fowl fodder per ton, add described Chinese medicine composition 0.5～1L, or in livestock and fowl drinking water per ton, add described Chinese medicine composition 1-4L; When described Chinese medicine composition is used as the treatment gastroenteropathy, in animal and fowl fodder per ton, add described Chinese medicine composition 2L, or in livestock and fowl drinking water per ton, add described Chinese medicine composition 1-4L.
The beneficial effect that the technical scheme that the embodiment of the invention provides is brought is: above-mentioned each medicine material medical material is organically combined; collaborative conditioning poultry body constitution; can bring into play the function of each medicine material medical material to greatest extent; thereby protect the gastrointestinal tract of poultry effectively, and the without any side effects and damage to other organ of poultry.And the present invention adopts microorganism fermentation process in the medicine course of processing, help to improve treatment and the preventive effect of above-mentioned Chinese medicine, accelerate poultry to the absorption of medicine, aspergillus niger and Bafillus natt use simultaneously can nurse one's health the intestinal microbial population balance, reduces the generation of other diseases.
The specific embodiment
The present invention adopts that spleen invigorating is regulated the flow of vital energy, the treatment rule of stomach function regulating antidiarrheal, and scientific composition is adjusted gastrointestinal function, to reach the purpose of protection gastrointestinal tract of livestock and fowls.The Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae be as monarch drug among the present invention, Rhizoma Atractylodis Macrocephalae invigorating the spleen and replenishing QI, invigorating the spleen and regulating the stomach; The Radix Aucklandiae, acrid in the mouth, bitter in the mouth are gone into spleen, stomach, large intestine, gallbladder meridian, energy promoting the circulation of QI to relieve pain, stomach function regulating antidiarrheal.Fructus Hordei Germinatus, nature and flavor are sweet, and are flat, return spleen, stomach warp, have promote qi circulation digestion promoting, and the effect of spleen benefiting and stimulating the appetite can help Rhizoma Atractylodis Macrocephalae spleen invigorating, helps Radix Aucklandiae circulation of qi promoting, regulates the flow of vital energy; Rhizoma Zingiberis, Xin Wen, warming spleen and stomach for dispelling cold, kind stomach warming intestinal, charred Radix Et Rhizoma Rhei is returned spleen, stomach, large intestine channel, but cooling blood and removing stasis, hemostasis, antidiarrheal, Rhizoma Coptidis is dicotyledon medicine ranunculaceae plant Rhizoma Coptidis, the root hair of Coptis deltoidea C.Y.Cheng et Hsiao, energy pathogenic fire purging, dampness cooperate with the Rhizoma Atractylodis Macrocephalae, transfer along negative and positive.The protection gastrointestinal function is played in above-mentioned all medicine combinations jointly, guarantees the fortuneization of water paddy, and removing heat from blood antidiarrheal reduces the damage to intestinal mucosa.
Embodiment 1
The Chinese medicine composition of present embodiment is made up of raw medicinal material: Rhizoma Zingiberis 5kg, Rhizoma Atractylodis Macrocephalae 5kg, Fructus Hordei Germinatus 5kg, Radix Aucklandiae 1kg, charred Radix Et Rhizoma Rhei 5kg and Rhizoma Coptidis 1kg.
The preparation method of present embodiment Chinese medicine composition is as follows:
(1) decocts the medicinal liquid step: get Rhizoma Zingiberis 5kg, Rhizoma Atractylodis Macrocephalae 5kg, Fructus Hordei Germinatus 5kg, Radix Aucklandiae 1kg, charred Radix Et Rhizoma Rhei 5kg and Rhizoma Coptidis 1kg and mix, mixed raw medicinal material is put into the Chinese medicine extraction jar, the purified water that adds 20 ℃ in the Chinese medicine extraction jar was soaked 2 hours, the weight that adds purified water is 8 times of raw medicinal material gross weight, then the Chinese medicine extraction jar being heated to 100 ℃ decocted 1 hour, filter, obtain decocting for the first time medicinal liquid; Add water in holding the Chinese medicine extraction jar of medicinal residues, the weight that adds water is 6 times of raw medicinal material gross weight, decocts 1 hour, filters to obtain decocting medicinal liquid for the second time, will decoct medicinal liquid for the first time and decoct medicinal liquid for the second time to mix;
(2) concentrated medicament step: utilize two effect concentrators that above-mentioned mixed decoction medicinal liquid is concentrated, concentrating pressure is-0.03Mpa, thickening temperature is 60 ℃, to be concentrated into relative density under the room temperature be 1.05 concentrated medicament until decocting medicinal liquid, and relative density is the density with respect to water herein;
(3) microbial fermentation step: the concentrated medicament in the concentrated medicament step is put into fermentation tank, adopt microbial fermentation, fermentation is that quantity is 2 * 10 with the microorganism in the seed liquor
7/ ml aspergillus niger and quantity are 2 * 10
7The mixed liquor of/ml Bafillus natt, in every 100L concentrated medicament, add sucrose 2.0kg, yeast powder 0.5kg, diammonium hydrogen citrate 0.1kg, magnesium sulfate 0.01kg, potassium dihydrogen phosphate 0.3kg and seed liquor 10ml, make the interior temperature of fermentation tank keep 38 ℃, the mixing speed of fermentation tank is 150 r/h, ventilation is 2L/h, continuing fermentation 30h, and the liquid that obtains is Chinese medicine composition, the Chinese medicine composition that obtains is respectively charged in the bottle, so that use and deposit.
Wherein, present embodiment adopts secondary to decoct, and as far as possible the extracts active ingredients in the Chinese medicine composition is come out, to reduce the cost of patent medicine; Certainly; explanation by present embodiment; common engineers and technicians also can draw following method without creative work in this area: medicinal residues are carried out at least three times decoct, obtain the effective ingredient in the Chinese medicine composition more fully, these methods also should be within protection scope of the present invention.
Embodiment 2
The Chinese medicine composition of present embodiment is made up of following raw medicinal material: Rhizoma Zingiberis 10kg, Rhizoma Atractylodis Macrocephalae 20kg, Fructus Hordei Germinatus 10kg, Radix Aucklandiae 8kg, charred Radix Et Rhizoma Rhei 15kg and Rhizoma Coptidis 5kg.
The preparation method of present embodiment Chinese medicine composition is as follows:
(1) decocts the medicinal liquid step: get Rhizoma Zingiberis 10kg, Rhizoma Atractylodis Macrocephalae 20kg, Fructus Hordei Germinatus 10kg, Radix Aucklandiae 8kg, charred Radix Et Rhizoma Rhei 15kg and Rhizoma Coptidis 5kg and mix, mixed raw medicinal material is put into the Chinese medicine extraction jar, the water logging bubble 4 hours that adds 40 ℃ in the Chinese medicine extraction jar, the weight that adds water is 12 times of raw medicinal material gross weight, then the Chinese medicine extraction jar is heated to 100 ℃ and decocted 3 hours, filter and obtain decocting for the first time medicinal liquid; Add water in holding the Chinese medicine extraction jar of medicinal residues, the weight that adds water is 10 times of raw medicinal material gross weight, decocts 3 hours, filters to obtain decocting medicinal liquid for the second time, will decoct medicinal liquid for the first time and decoct medicinal liquid for the second time to mix;
(2) concentrated medicament step: utilize two effect concentrators that above-mentioned mixed decoction medicinal liquid is concentrated, concentrating pressure is-0.08Mpa, thickening temperature is 80 ℃, to be concentrated into relative density under the room temperature be 1.15 concentrated medicament until decocting medicinal liquid, and relative density is the density with respect to water herein;
(3) microbial fermentation step: the concentrated medicament in the concentrated medicament step is put into fermentation tank, adopt microbial fermentation, fermentation is that quantity is 8 * 10 with the microorganism in the seed liquor
7/ ml aspergillus niger and quantity are 8 * 10
7The mixed liquor of/ml Bafillus natt, in every 100L concentrated medicament, add sucrose 3.0kg, yeast powder 1kg, diammonium hydrogen citrate 0.3kg, magnesium sulfate 0.03kg, potassium dihydrogen phosphate 0.6kg and seed liquor 30ml, make the interior temperature of fermentation tank keep 38 ℃, the mixing speed of fermentation tank is 150 r/h, ventilation is 2L/h, continuing fermentation 20h, and the liquid that obtains is Chinese medicine composition, the Chinese medicine composition that obtains is respectively charged in the bottle, so that use and deposit.
Embodiment 3
The Chinese medicine composition of present embodiment is made up of following raw medicinal material: Rhizoma Zingiberis 7.5 kg, Rhizoma Atractylodis Macrocephalae 12.5kg, Fructus Hordei Germinatus 7.5kg, Radix Aucklandiae 4.5kg, charred Radix Et Rhizoma Rhei 10kg and Rhizoma Coptidis 3kg.
The preparation method of present embodiment Chinese medicine composition is as follows:
(1) decocts the medicinal liquid step: get Rhizoma Zingiberis 7.5 kg, Rhizoma Atractylodis Macrocephalae 12.5kg, Fructus Hordei Germinatus 7.5kg, Radix Aucklandiae 4.5kg, charred Radix Et Rhizoma Rhei 10kg and Rhizoma Coptidis 3kg and mix, mixed raw medicinal material is put into the Chinese medicine extraction jar, the purified water that adds 30 ℃ in the Chinese medicine extraction jar was soaked 3 hours, the weight that adds purified water is 10 times of raw medicinal material gross weight, then the Chinese medicine extraction jar being heated to 100 ℃ decocted 2 hours, filter, obtain decocting for the first time medicinal liquid; Add water in holding the Chinese medicine extraction jar of medicinal residues, the weight that adds water is 8 times of raw medicinal material gross weight, decocts 2 hours, filters to obtain decocting medicinal liquid for the second time, will decoct medicinal liquid for the first time and decoct medicinal liquid for the second time to mix;
(2) concentrated medicament step: utilize two effect concentrators that above-mentioned mixed decoction medicinal liquid is concentrated, concentrating pressure is-0.05Mpa, thickening temperature is 70 ℃, to be concentrated into relative density under the room temperature be 1.10 concentrated medicament until decocting medicinal liquid, and relative density is the density with respect to water herein;
(3) microbial fermentation step: the concentrated medicament in the concentrated medicament step is put into fermentation tank, adopt microbial fermentation, fermentation is that quantity is 5 * 10 with the microorganism in the seed liquor
7/ ml aspergillus niger and quantity are 5 * 10
7The mixed liquor of/ml Bafillus natt, in every 100L concentrated medicament, add sucrose 2.5kg, yeast powder 0.75kg, diammonium hydrogen citrate 0.2kg, magnesium sulfate 0.02kg, potassium dihydrogen phosphate 0.45kg and seed liquor 20ml, make the interior temperature of fermentation tank keep 38 ℃, the mixing speed of fermentation tank is 150 r/h, ventilation is 2L/h, continuing fermentation 15h, and the liquid that obtains is Chinese medicine composition, the Chinese medicine composition that obtains is respectively charged in the bottle, so that use and deposit.
Embodiment 4
The Chinese medicine composition of present embodiment is made up of following raw medicinal material: Rhizoma Zingiberis 9kg, Rhizoma Atractylodis Macrocephalae 15kg, Fructus Hordei Germinatus 6kg, Radix Aucklandiae 6kg and charred Radix Et Rhizoma Rhei 8kg.
The preparation method of present embodiment Chinese medicine composition is as follows:
(1) decocts the medicinal liquid step: get Rhizoma Zingiberis 9kg, Rhizoma Atractylodis Macrocephalae 15kg, Fructus Hordei Germinatus 6kg, Radix Aucklandiae 6kg and charred Radix Et Rhizoma Rhei 8kg and mix, put into the Chinese medicine extraction jar mixing the back raw medicinal material, the purified water that adds 28 ℃ in the Chinese medicine extraction jar was soaked 3.5 hours, the weight that adds purified water is 8.5 times of raw medicinal material gross weight, then the Chinese medicine extraction jar being heated to 100 ℃ decocted 1.5 hours, filter, obtain decocting for the first time medicinal liquid; Add water in holding the Chinese medicine extraction jar of medicinal residues, the weight that adds water is 7 times of raw medicinal material gross weight, decocts 2.5 hours, filters to obtain decocting medicinal liquid for the second time, will decoct medicinal liquid for the first time and decoct medicinal liquid for the second time to mix;
(2) concentrated medicament step: utilize two effect concentrators that above-mentioned mixed decoction medicinal liquid is concentrated, concentrating pressure is-0.07Mpa, thickening temperature is 75 ℃, to be concentrated into relative density under the room temperature be 1.12 concentrated medicament until decocting medicinal liquid, and relative density is the density with respect to water herein;
(3) microbial fermentation step: the concentrated medicament in the concentrated medicament step is put into fermentation tank, adopt microbial fermentation, fermentation is that quantity is 4 * 10 with the microorganism in the seed liquor
7/ ml aspergillus niger and quantity are 4 * 10
7The mixed liquor of/ml Bafillus natt, in every 100L concentrated medicament, add sucrose 2.4kg, yeast powder 0.8kg, diammonium hydrogen citrate 0.25kg, magnesium sulfate 0.02kg, potassium dihydrogen phosphate 0.5kg and seed liquor 25ml, make the interior temperature of fermentation tank keep 37 ℃, the mixing speed of fermentation tank is 170 r/h, ventilation is 3L/h, continuing fermentation 13h, and the liquid that obtains is Chinese medicine composition, the Chinese medicine composition that obtains is respectively charged in the bottle, so that use and deposit.
The present invention adopts the seed mixture liquid of aspergillus niger and Bafillus natt, above-mentioned two kinds of strains can use all that Huankai Microbes Tech Co., Ltd., Guangdong provides aspergillus niger type strain and Bafillus natt type strain, two strains have the many places manufacturer production to sell in market, the range of choice is wider, and acquiring way is also more.These two kinds of strains the time can utilize polysaccharide in the concentrated medicament, protein etc. as the raw material of growth and breeding in growth, produce plurality of enzymes such as amylase, protease simultaneously, with the composition in the decomposition and inversion concentrated medicament, produce multivitamin, antibacterial substance.Behind these two kinds of microbial fermentations, transform in the concentrated medicament composition that can not directly be utilized by body, as part polysaccharide in the concentrated medicament is decomposed into oligosaccharide, monosaccharide, with the speed of action of quickening Chinese medicine composition, the utilization rate of raising Chinese medicine composition.
When this Chinese medicine composition is used as prevention, in animal and fowl fodder per ton, add this Chinese medicine composition 0.5～1L, or in livestock and fowl drinking water per ton, add Chinese medicine composition 1-4L of the present invention; When this Chinese medicine is used as the treatment gastroenteropathy, can add this Chinese medicine composition 2L in animal and fowl fodder per ton, or add Chinese medicine composition 1-4L of the present invention in livestock and fowl drinking water per ton, this administrated method is fit to above any embodiment.
Application test and effect:
1, company limited is cultured by Shouguang City, Shandong Province, and broiler is large quantities of in the plants in 2011 suffers from diarrhoea, and main reveal any symptoms is that feces is water sample, contains a large amount of indigested feedstuffs, and feed intake descends, spirit is depressed, astasia etc.In drinking-water, according to the Chinese medicine composition that adds the 2L embodiment of the invention 1 in the drinking-water per ton, safeguard normal intestinal flora, protection and reparation intestinal mucosa; use after 3 days continuously; the sx of having loose bowels of broiler, " punishment in advance " phenomenon reduces, and chicken is mined massively in the plant, and appetite is preliminary recovers normal.
2, pig farm, Jinan City, Shandong Province, in the ablactational baby pig stage, in feedstuff, interpolation 0.5L per ton Chinese medicine composition of the present invention, use the pig house of the Chinese medicine composition of the embodiment of the invention 2 to compare with untapped pig house, the ablactational baby pig survival rate improves 10%, weanling weight average every than untapped heavy 50g, the diarrhea of weaned piglets sickness rate is low by 20%, remarkable in economical benefits.
3, Cao County, Shandong Province breeding layer chicken specialty cooperative society, in July, 2011, because high temperature, amount of drinking water increases, and suffers from diarrhoea, and shows as violent diarrhoea, and feces is water sample, and feed intake descends.Dissect and find, glandular stomach ulcer, intestinal wall attenuation, hemorrhage, intestinal mucosa comes off, the small intestinal lymphadenectasis.According to the Chinese medicine composition that adds the 4L embodiment of the invention 3 in the drinking-water per ton, use the Chinese medicine composition 5 days of the embodiment of the invention 3 continuously, the laying hen watery diarrhea stops, and feed intake reaches normal level.
4, Xingtai city meat-type duck is cultured a meat-type duck plant of professional cooperative society, because the diversion water pollution is suffered from diarrhoea, shows as violent diarrhoea in August, 2011, and feces is water sample, and feed intake descends.Dissect and find, glandular stomach ulcer, intestinal wall attenuation, hemorrhage, intestinal mucosa comes off, the small intestinal lymphadenectasis.Chinese medicine composition according to adding the 3L embodiment of the invention 4 in the drinking-water per ton used Chinese medicine composition of the present invention 6 days continuously, and the meat-type duck watery diarrhea stops, and feed intake reaches normal level.
The above only is preferred embodiment of the present invention, and is in order to limit the present invention, within the spirit and principles in the present invention not all, any modification of doing, is equal to replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. the Chinese medicine composition for the protection of gastrointestinal tract of livestock and fowls is characterized in that, described Chinese medicine composition comprises the raw medicinal material of following ratio of weight and number: 5 ~ 15 parts of 1 ~ 8 part of 5 ~ 10 parts of Rhizoma Zingiberis, 5 ~ 20 parts of the Rhizoma Atractylodis Macrocephalaes, 5 ~ 10 parts in Fructus Hordei Germinatus, the Radix Aucklandiae and charred Radix Et Rhizoma Rheis.
2. the Chinese medicine composition for the protection of gastrointestinal tract of livestock and fowls according to claim 1 is characterized in that, also comprises 1 ~ 5 part Rhizoma Coptidis in the described Chinese medicine composition.
3. the Chinese medicine composition for the protection of gastrointestinal tract of livestock and fowls according to claim 2; it is characterized in that described Chinese medicine composition comprises the raw medicinal material of following ratio of weight and number: 1 part of 5 parts of Rhizoma Zingiberiss, 5 parts of the Rhizoma Atractylodis Macrocephalaes, 5 parts in Fructus Hordei Germinatus, 1 part of the Radix Aucklandiae, 5 parts of charred Radix Et Rhizoma Rheis and Rhizoma Coptidis.
4. the Chinese medicine composition of protection gastrointestinal tract of livestock and fowls according to claim 2; it is characterized in that described Chinese medicine composition comprises the raw medicinal material of following ratio of weight and number: 5 parts of 10 parts of Rhizoma Zingiberiss, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts in Fructus Hordei Germinatus, 8 parts of the Radix Aucklandiae, 15 parts of charred Radix Et Rhizoma Rheis and Rhizoma Coptidis.
5. the Chinese medicine composition of protection gastrointestinal tract of livestock and fowls according to claim 2; it is characterized in that described Chinese medicine composition comprises the raw medicinal material of following ratio of weight and number: 3 parts of 7.5 parts of Rhizoma Zingiberiss, 12.5 parts of the Rhizoma Atractylodis Macrocephalaes, 7.5 parts in Fructus Hordei Germinatus, 4.5 parts of the Radix Aucklandiae, 10 parts of charred Radix Et Rhizoma Rheis and Rhizoma Coptidis.
6. preparation method as any described Chinese medicine composition for the protection of gastrointestinal tract of livestock and fowls of claim 1-5 is characterized in that preparation method may further comprise the steps:
(1) decocts the medicinal liquid step: each raw medicinal material is mixed by weight ratio, decoct, obtain decocting medicinal liquid after the filtration;
(2) concentrated medicament step: the decoction medicinal liquid that obtains in the described decoction medicinal liquid step is concentrated, obtain concentrated medicament;
(3) microbial fermentation step: the concentrated medicament that obtains in the described concentrated medicament step is adopted microbial fermentation, can make described Chinese medicine composition.
7. the preparation method of the Chinese medicine composition for the protection of gastrointestinal tract of livestock and fowls according to claim 6, it is characterized in that, described decoction medicinal liquid step comprises: each raw medicinal material is mixed by weight ratio, be positioned in the Chinese medicine extraction jar, 8～10 times of amounts by raw medicinal material mixture total weight amount add water and descend immersion 2～4 hours at 20～40 ℃, heat then to 100 ℃ of decoctions 1～3 hour, filter, obtain decocting for the first time medicinal liquid; 6～10 times of flow control secondaries by raw medicinal material mixture total weight amount in holding the Chinese medicine extraction jar of medicinal residues add water, decoct 1～3 hour, filter, and obtain decocting medicinal liquid for the second time, will decoct medicinal liquid for the second time and decoct medicinal liquid with the first time and mix, and obtain decocting medicinal liquid.
8. according to the preparation method of claim 6 or 7 described Chinese medicine compositions for the protection of gastrointestinal tract of livestock and fowls; it is characterized in that; described concentrated medicament step comprises: with the decoction medicinal liquid that obtains in the described decoction medicinal liquid step adopt two imitate concentrators be-0.03 at pressure～-0.08MPa, temperature are to concentrate under 60～80 ℃ of conditions; be concentrated into that relative density is 1.09～1.15 under the room temperature, obtain concentrated medicament.
9. according to the preparation method of any described Chinese medicine composition for the protection of gastrointestinal tract of livestock and fowls of claim 6-8; it is characterized in that; described microbial fermentation step comprises: the concentrated medicament that described concentrated medicament step obtains is put into fermentation tank; in every 100L concentrated medicament, add sucrose 2.0～3.0kg; yeast powder 0.5～1.0 kg; diammonium hydrogen citrate 0.1～0.3 kg; magnesium sulfate 0.01～0.03 kg; potassium dihydrogen phosphate 0.3～0.6 kg and seed liquor 10～30ml; make the interior temperature of fermentation tank keep 32～40 ℃; the mixing speed of fermentation tank is 100～200r/h; ventilation is 1～4L/h; continuing fermentation 10～20h, the liquid that obtains is described Chinese medicine composition.
10. the preparation method of the Chinese medicine composition for the protection of gastrointestinal tract of livestock and fowls according to claim 9 is characterized in that described seed liquor comprises that quantity is 2 * 10
7～8 * 10
7The aspergillus niger of/ml and/or quantity are 2 * 10
7～8 * 10
7The Bafillus natt of/ml.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310207226.4A CN103251913B (en) | 2013-05-30 | 2013-05-30 | Traditional Chinese medicine composition for protecting gastrointestinal tract of livestock and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104225416A (en) * | 2014-06-29 | 2014-12-24 | 潍坊诺达药业有限公司 | Chinese veterinary drug for accelerating after-disease feed intake recovery of poultry and preparation method of Chinese veterinary drug |
| CN107744070A (en) * | 2017-09-28 | 2018-03-02 | 临汾市碧丰霖农业科技开发有限公司 | A kind of fig home poultry raising liquid |
| CN110522797A (en) * | 2018-05-23 | 2019-12-03 | 珠海岐微生物科技有限公司 | Charred RADIX ET RHIZOMA RHEI is adjusting the purposes in enteric microorganism |
| CN116159114A (en) * | 2023-03-16 | 2023-05-26 | 上海交通大学 | Novel fermentation preparation process and product of astragalus and dendrobium food stagnation-relieving drink |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102895565A (en) * | 2011-07-27 | 2013-01-30 | 天津瑞贝特科技发展有限公司 | Chinese medicinal composition with digestion promoting and food stagnation eliminating functions and its preparation method |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102895565A (en) * | 2011-07-27 | 2013-01-30 | 天津瑞贝特科技发展有限公司 | Chinese medicinal composition with digestion promoting and food stagnation eliminating functions and its preparation method |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104225416A (en) * | 2014-06-29 | 2014-12-24 | 潍坊诺达药业有限公司 | Chinese veterinary drug for accelerating after-disease feed intake recovery of poultry and preparation method of Chinese veterinary drug |
| CN104225416B (en) * | 2014-06-29 | 2017-05-03 | 潍坊诺达药业有限公司 | Chinese veterinary drug for accelerating after-disease feed intake recovery of poultry and preparation method of Chinese veterinary drug |
| CN107744070A (en) * | 2017-09-28 | 2018-03-02 | 临汾市碧丰霖农业科技开发有限公司 | A kind of fig home poultry raising liquid |
| CN110522797A (en) * | 2018-05-23 | 2019-12-03 | 珠海岐微生物科技有限公司 | Charred RADIX ET RHIZOMA RHEI is adjusting the purposes in enteric microorganism |
| CN116159114A (en) * | 2023-03-16 | 2023-05-26 | 上海交通大学 | Novel fermentation preparation process and product of astragalus and dendrobium food stagnation-relieving drink |
| CN116159114B (en) * | 2023-03-16 | 2023-11-28 | 上海交通大学 | Fermentation preparation process of astragalus, dendrobium and fructus forsythiae resolving beverage and product |
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| CN103251913B (en) | 2015-03-11 |
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