CN103237451A - Fungicidal mixtures - Google Patents

Abstract

Disclosed is fungicidal mixtures comprising, as active components, a fungicidal compound I selected from the group including kasugamycin, carpropamid, tricyclazole, and dicyclomet, and pyraclostrobin as a compound II in synergistic effective amounts.

Description

Fungicidal mixture

The present invention relates to Synergistic mixture, it is usingd the Synergistic effective dose and comprises following compound as active component:

1) a kind of Fungicidal compounds I that is selected from following group: the third oxygen goes out and embroiders amine (mepronil), tecloftalam (tecloftalam), thifluzamide (thifluzamide), fluorine mepanipyrim (diflumetorim), binapacryl (binapacryl), dinobuton (dinobuton), ferimzone (ferimzone), Bitertanol (bitertanol), alkene azoles alcohol (diniconazol-M), acid amides azoles (imiben-conazol), simeconazoles (simeconazol), pefurazoate (pefurazoate), piperazine, nuarimol (nuarimol), pyrifenox (pyrifenox), triforine (triforin), aldimorph, dodemorfe acetic acid esters (dodemorphacetat), pipron (piperalin), different thiophene bacterium ketone (octhilinon),

quinoline acid

the mould prestige of second (diethofencarb), Pencycuron (pencycuron), fluopicolide (fluopicolide), pyriofenon, blasticidin-S (blasticidin-S), kasugarnycin (kasugamycin), midolthromycin (mildiomycin), streptomycin (streptomycin), terramycin (oxytetracyclin), jinggangmeisu (validamycin A), ethofumesate (fluoroimid), Hinosan (edifenphos), iprobenfos (iprobenfos), Ppyrazophos (pyrazophos), Isoprothiolane (isoprothiolane), botran (dicloran), pcnb (quintozene), tecnazene (tecnazen), tolelofos-methyl (tolclofos-methyl), biphenyl (biphenyl), kobam (etridiazol), flumorph (flumorph), ferbam (ferbam), metham-sodium (metam), anilazine (anilazin), Euparen (dichlofluanid), antiphen (dichlorophen), flusulfamide (flusulfamid), guazatine (guazatin), biguanides acetate (guazatin-acetat), valida (validamycin), Polyoxin (polyoxin b), pyroquilon (pyroquilon), tricyclazole (tricyclazol), carpropamide (carpropamid), two chlorine zarilamids (dicyclomet), tiadinil (tiadinil), bronopol (bronopol), chinomethionat (chinomethionat), two ethoxy imidazoles prestige (debacarb), diclomezine (diclomezin), benzene enemy fast (difenzoquat), benzene opposes fast methylsulfuric acid ester (difenzoquatmethylsulfat), diphenylamines (diphenylamin), fluorine biphenyl bacterium (flumetover), flusulfamide (flusulfamid), methasulfocarb (methasulfocarb), N-Serve (nitrapyrin), isopropyl disappear (nitrothal-isopropyl), the third oxygen quinoline (proquinazid), tebufloquin, tecloftalam (tecloftalam) and azoles bacterium piperazine (triazoxid), with

2) as the pyraclostrobin (pyraclostrobin) of Compound I I.

These said mixtures are hereinafter also referred to as " mixture of the present invention ".

In addition, the present invention relates to purposes in this class mixture of preparation of a kind of method of using mixture of the present invention control plant-pathogenic harmful fungoid and Compound I and Compound I I and the composition that comprises this mixture.

In addition; the present invention relates to a kind of method of preventing and treating the plant-pathogenic harmful fungoid, comprise and make plant-pathogenic harmful fungoid, its habitat, breeding ,Qi place, place or protection in order to avoid the plant of fungal attack, soil or plant propagation material contact with the above defined mixture of effective dose.

In addition, the present invention also comprises a kind of protective plant propagating materials in order to avoid the method for plant-pathogenic harmful fungoid comprises described plant propagation material is contacted with the mixture of the present invention of antifungal effective dose.

Term " plant propagation material " is interpreted as meaning that all breedings parts of plant are as seed, and can be for the asexual vegetable material of breeding plant for example, as cutting and stem tuber (potato).This comprises seed, root, fruit, stem tuber, bulb, rhizome, spray, stripping and other plant part, is included in after being sprouted by soil or rice shoot and the seedling of the rear transplanting of emerging.These seedling also can be protected by immersion or pouring by all or part of processing before transplanting.In particularly preferred embodiments, the term propagating materials refers to seed.

The invention further relates to plant protecting activity composition and a kind of method from mixture of the present invention to plant that use with the synergistic function that improves plant health.

Compound I and II and fungicidal action thereof and preparation method thereof are normally known.For example, commercial compound, especially can be referring to The Pesticide Manual except other documents, and the 14th edition, British Crop Protection Council (2006).

It must be noted that kasugarnycin (kasugamycin) herein, but also can as kasugarnycin hydrochloride, kasugarnycin hydrochloride hydrate form, exist with agricultural salt.

The FAQs run in the fungi prevention and control field is to need the dose rate that reduces active component to reduce or to avoid hostile environment or toxicity impact, and the while is the control fungi effectively.

For the present invention, term plant-pathogenic harmful fungoid is abbreviated as " harmful fungoid " hereinafter.

Another problem run into is the fungi control agent that effective control wide spectrum harmful fungoid need to be provided.

Also need to have concurrently and knock down active and prevent and treat for a long time, be i.e. the fungi control agent of snap action and long term.

With fungicide, use another relevant difficult problem to be that various Fungicidal compounds repeat and single-mindedly use the quick selection that causes in many cases harmful fungoid, it is natural or adaptability tolerance to described active ingredient deposits yields.Therefore, need can contribute to prevent or overcome the fungi control agent of tolerance.

Existing another problem of the present invention is the composition that needs to improve plant (a kind of usually and hereinafter referred to as the conventional method of " plant health ").

Term " plant health " comprises that each Plants irrelevant with the fungi control improves.For example, the crop characteristic of the favourable character that can mention for improving, it comprises: emerge, crop yield, protein content, oil content, content of starch, more flourishing root system (root growth of improvement), the stress tolerance improved is (for example, to arid, heat, salt, UV, water, cold tolerance), reduce ethene (reducing the generation of ethene and/or the acceptance of ethene suppressing), increase is tillered, improve plant height, larger blade, dead basal leaf still less, stronger tillering, greener leaf color, pigment content, photochemical vitality, need input thing (as fertilizer or water) still less, need seed still less, more voluminous tillers, prematurity more, kernel maturity early, plant still less falls against (lodging), the spray growth increased, the plant vigor improved, the plant orthostatic improved is with early and better rudiment, or any other advantage well-known to those skilled in the art.

Therefore, the purpose of this invention is to provide to solve and reduce dose rate and/or widen activity profile and/or have concurrently and knock down the Fungicidal mixture that the problem of plant health was controlled and/or promoted to active and long-term control efficiency and/or tolerance.

We find that this purpose can partially or completely realize by comprising the complex mixture that starts defined reactive compound.

Especially find, when starting defined mixture while being applied to plant, plant part, plant propagation material (preferred seed) or its growth place, with using separately each compound, can compare by obtainable control rate, described mixture demonstrate remarkable improvement the control fungi effect and/or be suitable for improving plant health.

The effect of finding mixture of the present invention is improved effect considerably beyond antifungal and/or the plant health of existing single-activity compound in this mixture.

In addition, we find to compare with possible the control rate of each compound, simultaneously (i.e. associating or separate) administered compound I and Compound I I or administered compound I and Compound I I can improve the control efficiency (Synergistic fungicidal mixtures) to harmful fungoid successively.

In addition, we find to compare with the possible plant health effect of each compound, (i.e. associating or separately) administered compound I and Compound I I or administered compound I and Compound I I provide the plant health effect (Synergistic mixture, wherein Synergistic is the plant health Synergistic) of improving successively simultaneously.

In particularly preferred embodiment of the present invention, find that mixture of the present invention is particularly suited for preventing and treating the plant pathogenic fungi on rice.In addition, also find that mixture of the present invention can be used for preventing and treating the plant pathogenic fungi in paddy field.

The weight ratio of each mixture that comprises Fungicidal compounds I and Fungicidal compounds II is 1:500-500:1, is preferably 1:100-100:1, and more preferably 1:25-25:1, most preferably be 1:10-10:1.

In a more preferred embodiment, described mixture comprises Fungicidal compounds I and the Compound I I that is selected from kasugarnycin, carpropamide, two chlorine zarilamid and tricyclazole, wherein preferably, the weight ratio of each mixture that comprises Fungicidal compounds I and Fungicidal compounds II is 1:500-500:1, be preferably 1:100-100:1, more preferably 1:25-25:1, most preferably be 25:1-1:2 (I:II).

Most preferably, mixture of the present invention is usingd the Synergistic effective dose and is comprised as the pyraclostrobin of Compound I I with as the kasugarnycin of Compound I I, wherein preferably, the weight ratio of each mixture that comprises Fungicidal compounds I and Fungicidal compounds II is 1:500-500:1, be preferably 1:100-100:1, more preferably 1:25-25:1, most preferably be 1:10-10:1.

The Synergistic effective dose of also most preferably usining comprises the mixture as Compound I as pyraclostrobin Compound I I and carpropamide, wherein preferably, the weight ratio of each mixture that comprises Fungicidal compounds I and Fungicidal compounds II is 1:500-500:1, be preferably 1:100-100:1, more preferably 1:25-25:1, most preferably be 1:10-10:1.

The Synergistic effective dose of also most preferably usining comprises as pyraclostrobin Compound I I and the mixture of two chlorine zarilamids as Compound I, wherein preferably, the weight ratio of each mixture that comprises Fungicidal compounds I and Fungicidal compounds II is 1:500-500:1, be preferably 1:100-100:1, more preferably 1:25-25:1, most preferably be 1:10-10:1.

The Synergistic effective dose of also most preferably usining comprise pyraclostrobin as Compound I I and tricyclazole the mixture as Compound I, wherein preferably, the weight ratio of each mixture that comprises Fungicidal compounds I and Fungicidal compounds II is 1:500-500:1, be preferably 1:100-100:1, more preferably 1:25-25:1, most preferably be 1:10-10:1.

The Synergistic effective dose of most preferably usining comprise pyraclostrobin as Compound I I and kasugarnycin the mixture as Compound I, wherein preferably, the weight ratio of each mixture that comprises Fungicidal compounds I and Fungicidal compounds II is 1:500-500:1, be preferably 1:100-100:1, more preferably 1:25-25:1, most preferably be 1:10-10:1.

The Synergistic effective dose of also most preferably usining comprise pyraclostrobin as Compound I I and carpropamide the mixture as Compound I, wherein preferably, the weight ratio of each mixture that comprises Fungicidal compounds I and Fungicidal compounds II is 1:500-500:1, be preferably 1:100-100:1, more preferably 1:25-25:1, most preferably be 1:10-10:1.

The Synergistic effective dose of also most preferably usining comprises pyraclostrobin as Compound I I and the mixture of two chlorine zarilamids as Compound I, wherein preferably, the weight ratio of each mixture that comprises Fungicidal compounds I and Fungicidal compounds II is 1:500-500:1, be preferably 1:100-100:1, more preferably 1:25-25:1, most preferably be 1:10-10:1.

Mentioned above each mixture of the present invention can further comprise one or more insecticides, fungicide, weed killer herbicide.

For purposes of the present invention, mixture of the present invention can be changed into to the normal compound agent, as solution, emulsion, suspension, pulvis, powder, paste and particle.Type of service depends on specific expection purpose; Should guarantee in each case the meticulous of mixture of the present invention and be uniformly distributed.Prepared in a known way (referring to US3 by preparaton, 060, 084, EP-A707445 (for liquid concentrate), Browning: " Agglomeration ", Chemical Engineering, on December 4th, 1967, 147-48, Perry ' s Chemical Engineer ' s Handbook, the 4th edition, McGraw-Hill, New York, 1963, 8-57 reaches each page subsequently, WO91/13546, US4, 172, 714, US4, 144, 050, US3, 920, 442, US5, 180, 587, US5, 232, 701, US5, 208, 030, GB2, 095, 558, US3, 299, 566, Klingman:Weed Control as a Science (J.Wiley& Sons, New York, 1961), Hance etc.: Weed Control Handbook (the 8th edition, Blackwell Scientific, Oxford, 1989) and Mollet, H. and Grubemann, A.:Formulation Technology (Wiley VCH Verlag, Weinheim, 2001).

Described agrochemical formulation also can comprise auxiliary agent common in agrochemical formulation.Adjuvant used specific administration form and the active substance of depending on respectively.

The example of suitable auxiliary agents is solvent, solid carrier, dispersant or emulsifier (for example other solubilizers, protective colloid, surfactant and adhesive); organic and inorganic thickening agent, bactericide, antifreezing agent, defoamer, suitable words also have colouring agent and tackifier or adhesive (for example, for the seed treatment preparaton).

Suitable solvent is water, organic solvent, for example, in to high boiling mineral oil fractions as kerosene or diesel oil, also has in addition coal tar, and the oil of plant or animal origin, aliphatic series, ring-type and aromatic hydrocarbons, for example toluene, dimethylbenzene, paraffin, tetrahydronaphthalene, alkylated naphthalene or derivatives thereof, alcohols is as methyl alcohol, ethanol, propyl alcohol, butanols and cyclohexanol, glycols, ketone is as cyclohexanone and gamma-butyrolacton, the fatty acid dimethylformamide, fatty acid and fatty acid ester and intensive polar solvent, for example amine is as 1-METHYLPYRROLIDONE.

Solid carrier is that ore deposit soil is as silicate, silica gel, talcum, kaolin, lime stone, lime, chalk, bole, loess, clay, dolomite, diatomite, calcium sulphate, magnesium sulfate, magnesia; The synthetic material ground; Fertilizer is as ammonium sulfate, ammonium phosphate, ammonium nitrate, urea; And the product of plant origin is as flour, bark powder, wood powder and shuck powder, cellulose powder and other solid carriers.

Suitable surfactant (auxiliary agent, wetting agent, tackifier, dispersant or emulsifier) be aromatic sulfonic acid as lignosulphonic acid (

type, Norway Borregaard), phenolsulfonic acid, naphthalene sulfonic acids (

type, Akzo Nobel, USA), the dibutyl naphthalene sulfonic acids (

type, Germany BASF) and the alkali metal of fatty acid, alkaline earth metal and ammonium salt, alkylsulfonate, alkylaryl sulfonates, alkyl sulfate, lauryl ether sulfate, aliphatic alcohol sulfate, and sulphation 16-, 17-and octadecanol, the sulphated fatty alcohol glycol ether, also has in addition the condensation product of naphthalene or naphthalene sulfonic acids and phenol and formaldehyde, NONIN HS 240, the ethoxylation isooctylphenol, octyl phenol, nonyl phenol, the alkyl phenyl polyglycol ether, tributyl phenyl polyglycol ether, three stearyl phenyl polyglycol ethers, alkyl aryl polyether alcohol, alcohol and fatty alcohol/ethylene oxide condensation product, ethoxylated castor oil, polyoxyethylene alkyl ether, the ethoxylation polyoxypropylene, laruyl alcohol polyglycol ether acetal, sorbitol ester, the lignin sulfite waste liquor, and protein, albuminate, polysaccharide (for example methylcellulose), hydrophobically modified starch, polyvinyl alcohol (

type, Switzerland Clariant), polycarboxylate (

type, German BASF), the poly-alkoxylation thing, polyvinylamine (

type, German BASF), PVP(polyvinyl pyrrolidone) and copolymer thereof.

The example of thickener (giving the mobile performance of preparaton with modification, i.e. high viscosity under inactive state and the low viscous compound in agitation) be polysaccharide and organic and inorganic clay as xanthans (

, CP Kelco, U.S.A.),

23 (French Rhodia),

(R.T.Vanderbilt, U.S.A.) or

(Engelhard Corp., NJ, USA).

Can add bactericide with anticorrosion and stablize this preparaton.The example of suitable antiseptic agent be based on antiphen and benzylalcohol hemiformal those (ICI's

or Thor Chemie

rS and Rohm& Haas's

mK), and isothiazolinone derivatives as alkyl isothiazole quinoline ketone and BIT class (Thor Chemie

mBS).

The example of suitable antifreezing agent is ethylene glycol, propane diols, urea and glycerine.

The example of defoamer be polysiloxane emulsion (for example

sRE, German Wacker or , French Rhodia), long-chain alcohol, fatty acid, soap, organofluorine compound and composition thereof.

Suitable colouring agent is low aqueous solubility pigment and water-soluble dye.The example that can mention is the title rhodamine B, C.I. pigment red 112, C.I. solvent red 1, pigment blue 15: 4, pigment blue 15: 3, pigment blue 15: 2, pigment blue 15: 1, alizarol saphirol 80, pigment yellow 1, pigment yellow 13, pigment red 112, pigment red 4 8:2, pigment red 4 8:1, paratonere 57:1, paratonere 53:1, pigment orange 43, pigment orange 34, pigment orange 5, pigment green 36, pigment Green 7, Pigment white 6, pigment brown 25, alkaline purple 10, alkalescence purple 49, CI 45430, acid red 52, azogeramine 4, acid blue 9, acid yellow 23, alkali red 1:1 0, alkali red 1:1 08.

The example of tackifier or adhesive be PVP(polyvinyl pyrrolidone), polyvinyl acetate, polyvinyl alcohol and cellulose ether (

, Japanese Shin-Etsu).

Powder, broadcast sowing material and pulvis can by each active component by existing in compound, mixture of the present invention and suitable other active substances mix with at least one solid carrier or prepared by simultaneous grinding.

Particle can be by preparing active substance and solid carrier adhesion as coated particle, impregnated granules and homogeneous particle.The example of solid carrier is that ore deposit soil is as silica gel, silicate, talcum, kaolin, activated clay (attaclay), lime stone, lime, chalk, bole, loess, clay, dolomite, diatomite, calcium sulphate, magnesium sulfate, magnesia; The synthetic material ground; Fertilizer is as ammonium sulfate, ammonium phosphate, ammonium nitrate, urea; And the product of plant origin is as flour, bark powder, wood powder and shuck powder, cellulose powder and other solid carriers.

The example of preparaton type is: suspension (SC, OD, FS), emulsifiable concentrate (EC), emulsion (EW, EO, ES), paste, lozenge, wetability powder or pulvis (WP, SP, SS, WS, DP, DS) or particle (GR, FG, GG, MG), it can be water-soluble or wetability, and for the treatment of plant propagation material the gel formulation (GF) as seed, this paper further in detail illustration is as follows:

1. the types of compositions of dilute with water

I) water-soluble concentrate (SL, LS)

The compound of 10 weight portion mixture of the present invention is dissolved in 90 weight parts waters or water-soluble solvent.As an alternative, add wetting agent or other auxiliary agents.Active substance dissolves when dilute with water.Obtain in this way the preparaton that activity substance content is 10 % by weight.

Ii) dispersed concentrate (DC)

Be dissolved in 70 weight portion cyclohexanone by the compound of 20 weight portion mixture of the present invention and add 10 weight portion dispersants as PVP(polyvinyl pyrrolidone).Dilute with water obtains dispersion.Activity substance content is 20 % by weight.

Iii) emulsifiable concentrate (EC)

Be dissolved in 75 weight portion dimethylbenzene by the compound of 15 weight portion mixture of the present invention and add calcium dodecyl benzene sulfonate and castor oil ethoxylate (5 weight portions in each case).Dilute with water obtains emulsion.The activity substance content of said composition is 15 % by weight.

Iv) emulsion (EW, EO, ES)

Be dissolved in 35 weight portion dimethylbenzene by the compound of 25 weight portion mixture of the present invention and add calcium dodecyl benzene sulfonate and castor oil ethoxylate (5 weight portions in each case).Introduce in 30 weight parts waters by this mixture and make the homogeneous emulsion by mulser (Ultraturrax).Dilute with water obtains emulsion.The activity substance content of said composition is 25 % by weight.

V) suspension (SC, OD, FS)

The compound of 20 weight portion mixture of the present invention pulverized and added 10 weight portion dispersants and wetting agent and 70 weight parts waters or organic solvent in the ball mill stirred, obtaining meticulous active substance suspension.Dilute with water obtains stable active substance suspension.The activity substance content of said composition is 20 % by weight.

Vi) water-dispersible granule and water-soluble granular (WG, SG)

By the compound grinding in small, broken bits of 50 weight portion mixture of the present invention and add 50 weight portion dispersant and wetting agents, for example, by commercial plant (extruder, spray tower, fluid bed), be made into water dispersible or water-soluble granular.Dilute with water obtains stable active substance dispersion or solution.The activity substance content of said composition is 50 % by weight.

Vii) water dispersible pow-ders and water-soluble powder (WP, SP, SS, WS)

The compound of 75 weight portion mixture of the present invention is ground in the rotor-stator grinding machine and add 25 weight portion dispersants, wetting agent and silica gel.Dilute with water obtains stable active substance dispersion or solution.The activity substance content of said composition is 75 % by weight.

Viii) gel (GF)

Grind the compound of 20 weight portion mixture of the present invention and add 10 weight portion dispersants, 1 weight portion gelling agent, wetting agent and 70 weight parts waters or organic solvent and obtain the delicate suspensions of active substance in stirring ball mill.Dilute with water obtains the stable suspension of active substance, obtains thus the composition that activity substance content is 20 % by weight.

2. the types of compositions of using without dilution

Ix) but dusting powder (DP, DS)

By the compound grinding in small, broken bits of 5 weight portion mixture of the present invention and with 95 weight portion kaolin in small, broken bits, fully mix.But this obtains the dusting composition that activity substance content is 5 % by weight.

X) particle (GR, FG, GG, MG)

By the compound grinding in small, broken bits of 0.5 weight portion mixture of the present invention and in conjunction with 99.5 weight portion carriers.Linear method be extrude, atomized drying or bed process.This obtains the particle of using without dilution that activity substance content is 0.5 % by weight.

Xi) ULV solution (UL)

The compound of 10 weight portion mixture of the present invention is dissolved in to 90 weight portion organic solvents as in dimethylbenzene.This obtains the composition of using without dilution that activity substance content is 10 % by weight.

Described agrochemical formulation comprises the 0.01-95 % by weight usually, preferably 0.1-90 % by weight, the most preferably active substance of 0.5-90 % by weight.The compound of mixture of the present invention is with 90-100%, and preferably the purity of 95-100% (according to the NMR spectrum) is used.

The compound of mixture of the present invention can be directly or with its composition forms (but but for example with Direct spraying solution, powder, suspension, dispersion, emulsion, oil dispersion, paste dusting product, broadcast sowing by material or particle form) by spraying, atomization, dusting, broadcast sowing, brush, flood or water and use.Administration form depends on the expection purpose fully; Be intended in each case to guarantee the compound that exists in mixture of the present invention may be the thinnest distribution.

Can by emulsion concentrates, paste or wetability powder (sprayable powder, oil dispersion), be prepared by adding water by moisture administration form.In order to prepare emulsion, paste or oil dispersion, can by wetting agent, tackifier, dispersant or emulsifier by this material directly or after being dissolved in oil or solvent in water homogenizing.Perhaps can prepare the concentrate and such concentrate that are formed by active substance, wetting agent, tackifier, dispersant or emulsifier and suitable solvent or oil and be suitable for dilute with water.

Active material concentration in the instant preparation can change in relative broad range.It typically is the 0.0001-10 % by weight, preferred 0.001-1 % by weight, the compound based on mixture of the present invention.

The compound of mixture of the present invention also can wherein can be used and comprise the composition that surpasses 95 % by weight active substances successfully for ultra low volume method (ULV), or even uses the active substance that does not contain additive.

Various types of oil, wetting agent, adjuvant, weed killer herbicide, fungicide, other agricultural chemicals or bactericide can be added in reactive compound, suitable words are until just add (bucket mixes) before being close to use.These reagent can be with the compound of mixture of the present invention with 1:100-100:1, and preferably the weight ratio of 1:10-10:1 is mixed.

The present composition also can contain fertilizer as ammonium nitrate, urea, potash and perphosphate, phytotoxin and plant growth regulator and safener.These can with above-mentioned composition successively or be combined with, suitable words also only add (bucket mixes) before being close to use.For example can be before or after processing with fertilizer with the present composition plant of spraying.

In mixture, contained compound can be simultaneously as defined above (i.e. associating or separately) or use successively, selects the time interval of each time between using still with q.s, to be present in site of action with the active substance of guaranteeing at first to use when using other active substances.Order of administration is unimportant to effect of the present invention.

According to the present invention, described Compound I and Compound I I are interpreted as referring to that at least described Compound I and Compound I I are present in site of action (harmful fungoid to be prevented and treated or its habitat are as the plant, plant propagation material (especially seed), surface, material or the soil that infect and to be protected in order to avoid the plant of fungal attack, plant propagation material (especially seed), soil, surface, material or space) with effective dose simultaneously.

This can be by simultaneously, combine (for example, with the mixed thing of bucket) or separate, or administered compound I and Compound I I and obtain successively, wherein select the time interval of each time between using still with q.s, to be present in site of action with the active substance of guaranteeing at first to use when using other active substances.Order of administration is unimportant to effect of the present invention.

In mixture of the present invention, the weight ratio of each compound depends on the performance of the compound of mixture of the present invention usually.

The compound of mixture of the present invention can separately be used or partially or completely be mixed with each other and prepare composition of the present invention.Also can be using it as binding compositions as the packaging kit of each several part, pack and further use.

In one embodiment of the invention, packaging kit can comprise the component that one or more (comprising all) can be used for preparing agrochemical composition of the present invention.But for example these packaging kit inclusion compound I and Compound I I and/or helper component and/or other agricultural chemical compounds (for example insecticide or weed killer herbicide) and/or growth regulator component.One or more components can be combined or preparation in advance.More than two kinds of components, be provided in those embodiments in packaging kit therein, described component can combine together and former state is packaged in single container as in tank, bottle, bucket, capsule, bag or case.In other embodiments, two or more components of packaging kit can separately be packed, i.e. not preparation in advance.Therefore, packaging kit can comprise one or more autonomous container as tank, bucket, bottle, capsule, bag or case, the independent component that wherein each container comprises agrochemical composition.In these two kinds of forms, a certain component of packaging kit can separate with other components or together with use or as the component of binding compositions of the present invention for the preparation of composition of the present invention.

The user uses composition of the present invention by pre-metering device, musette bag sprayer, aerosol can or spraying airplane usually.Now described agrochemical composition water and/or buffer are complemented to required application concentration, wherein suitable words can add other auxiliary agents, obtain with spray liquid or agrochemical composition of the present invention thus.Usually per hectare agricultural use district uses the 50-500 liter, and preferably 100-400 rises and uses spray liquid.

According to an embodiment, the user can own will be mixed with composition (or preparaton) in aerosol can, for example each compound of the mixture of the present invention of the each several part of the each several part of packaging kit or mixture of the present invention, and suitable words can add other auxiliary agents (bucket mixes).

In another embodiment, the user can will be mixed with composition or partly-premixed component in aerosol can, for example each compound of the mixture of the present invention of the component of inclusion compound I and Compound I I, and suitable words can add other auxiliary agents (bucket mixes).

In another embodiment, can combine (for example, after bucket is mixed) or use successively each component of the present composition or partly-premixed component, for example the component of inclusion compound I and Compound I I.

As mentioned above; the present invention includes a kind of method for harmful fungoid, wherein use the described fungi of mixture process, its habitat, the breeding ,Qi place, place or to be protected in order to avoid the plant of fungal attack, soil or plant propagation material (preferred seed) of antifungal effective dose.

Advantageously, mixture of the present invention is suitable for preventing and treating following harmful fungoid: for example, for example, Albugo (Albugo) (white blister) on ornamental plant, vegetables (white rust (A.candida)) and sunflower (salsify white rust (A.tragopogonis)), for example, for example, for example, Alternaria (Alternaria) (black spot) on vegetables, rape (rape gives birth to chain lattice spores (A.brassicola) or alternaria brassica (A.brassicae)), sugar beet (A.tenuis), fruit, rice, soybean, potato (early epidemic chain lattice spore (A.solani) or chain lattice spore (A.alternata)) and tomato (early epidemic chain lattice spore (A.solani) or chain lattice spore (A.alternata)) and wheat, Aphanomyces on sugar beet and vegetables (Aphanomyces), Ascochyta on Cereal and vegetables (Ascochyta), for example large wheat husk two spores (A.hordei) on the A.tritici on wheat (shell two spore leaf blights) and barley, Bipolaris (Bipolaris) and Drechslera (Drechslera) (epigamous: cochliobolus belongs to (Cochliobolus)), the leaf spot on corn (Bipolaris maydis (D.maydis) and Bipolaris zeicola (B.zeicola)) for example, for example (wheat root-rot Bipolaris (B.sorokiniana) and the rice Bipolaris (B.oryzae) on rice and lawn for example of the spot blight on Cereal, for example, wheat powdery mildew on Cereal (wheat or barley) (Blumeria (old name: Erysiphe) graminis) (powdery mildew), for example, for example, Botrytis cinerea (Botrytis cinerea) (epigamous: Botrytis cinerea (Botryotinia fuckeliana): gray mold) on fruit and berry (strawberry), vegetables (lettuce, carrot, celeriac and cabbage), rape, flowers, grapevine, forest crop and wheat, lettuce dish stalk mould (Bremia lactucae) (downy mildew) on lettuce, long beak shell on broad leaf tree and evergreen tree belongs to (Ceratocystis) (synonym line mouth shell belongs to (Ophiostoma)) (rotting or droop), for example the elm wilt (C.ulmi) (Dutch elm disease) on elm, for example, for example, for example, Cercospora (Cercospora) (tail spore leaf spot) on corn (corn tail spore bacterium (C.zeae-maydis)), rice, sugar beet (beet is given birth to tail spore (C.beticola)), sugarcane, vegetables, coffee, soybean (Germ To Soybean Frogeye Leaf Spot (C.sojina) or Cercospora kikuchii (C.kikuchii)) and rice, the tomato leaf mildew) and for example, Cladosporium (Cladosporium) on Cereal (the careless bud branch spore (C.herbarum) (ear rot) on wheat) tomato (Cladosporium fulvum (C.fulvum) for example:, ergot on Cereal (Claviceps purpurea) (ergot), corn (grey length wriggle spore (C.carbonum)), Cereal (standing grain cochliobolus (C.sativus) for example, phorozoon: wheat root-rot Bipolaris) and rice (palace section cochliobolus (C.miyabeanus) for example, phorozoon: the cochliobolus the long spore (H.oryzae) of wriggling of paddy rice) belongs to (Cochliobolus) (phorozoon: the Helminthosporium of Bipolaris (Helminthosporium)) (leaf spot), cotton (for example cotton anthracnose bacterium (C.gossypii)), (for example standing grain is given birth to anthrax bacteria (C.graminicola) to corn: stem rot), berry, potato (watermelon anthrax bacteria (C.coccodes) for example: diplostomiasis), for example, for example, perverse dish spore on Kidney bean (bean anthrax bacteria (C.lindemuthianum)) and soybean (Colletotrichum truncatum (C.truncatum) or glue born of the same parents anthrax-bacilus (C.gloeosporioides)) belongs to (Colletotrichum) (epigamous: enclose small cluster shell Pseudomonas (Glomerella)) (anthracnose), corticium (Corticium), for example rice Shang De Bamboo grass wood photovoltaicing leather bacteria (C.sasakii) (banded sclerotial blight), Cucumber Target Leaf Spot bacterium on soybean and ornamental plant (Corynespora cassiicola) (leaf spot), the rust staining germ belongs to (Cycloconium), for example C.oleaginum on Chinese olive tree, fruit tree, grapevine (C.liriodendri for example, Blackfoot Disease) and view and admire ginseng on tree and give birth to Ramularia (Cylindrocarpon) (for example fruit tree putrefaction disease or grapevine Blackfoot Disease, epigamous: Nectria (Nectria) or lady's slipper mycorhiza Pseudomonas (Neonectria)) epigamous: Neonectria liriodendri:, lineae ablicantes plumage bacterium on soybean (Dematophora (epigamous: Rosellinia) necatrix) (root rot and stem rot), north stem canker Pseudomonas (Diaporthe), for example north of the soybean on soybean stem canker (D.phaseolorum) (vertical withered ulcer), corn, Cereal for example, as barley (the navel spore (D.teres) of wriggling in the barley filigree, net blotch) and wheat (D.tritici-repentis for example: brown spot), Drechslera (synonym Helminthosporium, epigamous: nuclear cavity Pseudomonas (Pyrenophora)) on rice and lawn, Eschka (Esca) (grapevine droop, die back disease) on the grapevine caused by the brown pore fungi of spot (Formitiporia (synonym Phellinus) punctata), F.mediterranea, Phaeomoniella chlamydospora (old Phaeoacremonium chlamydosporum by name), Phaeoacremonium aleophilum and/or grape seat chamber bacterium (Botryosphaeria obtuse), anthracnose) and grapevine (grape Elsinochrome (E.ampelina): the Elsinoe anthracnose) (Elsinoe) a kind of fruit, such as apple, pear, etc. (E.pyri), berry (raspberry Elsinochrome (E.veneta):, rice leaf smut (Entyloma oryzae) (leaf smut) on rice, Epicoccum on wheat (Epicoccum) (smut), sugar beet (beet powdery mildew (E.betae)), vegetables (for example pea powdery mildew (E.pisi)) for example, for example, as the Erysiphe (Erysiphe) (powdery mildew) on cucumber (two spore powdery mildews (E.cichoracearum)), cabbage, rape (E.cruciferarum), fruit tree, grapevine and view and admire the side Curvularia lunata (Eutypa lata) (Eutypa canker or tip die-back, phorozoon: Cytosporina lata, synonym Libertella blepharis) on tree, for example, prominent navel Helminthosporium (Exserohilum) (synonym Helminthosporium) on corn (Exserohilum turcicum (E.turcicum)), Fusarium on each Plants (Fusarium) (epigamous: Gibberella (Gibberella)) (droop, root rot and stem rot), for example for example, fusarium graminaria (F.graminearum) on Cereal (wheat or barley) or machete sickle spore (F.culmorum) (root rot and silver point sick), sharp sickle spore (F.oxysporum) on tomato, the eggplant sickle spore (F.solani) on soybean and the wheel branch sickle spore (F.verticillioides) on corn, for example, gaeumannomyce (Gaeumannomyces graminis) (full rot) on Cereal (wheat or barley) and corn, Cereal (for example Gibberella zeae (G.zeae)) and rice (gibberella fujikuroi (G.fujikuroi) for example: the Gibberella bakanae disease), cotton anthracnose bacterium (G.gossypii) on apple anthrax bacteria on grapevine, a kind of fruit, such as apple, pear, etc. and other plant (Glomerella cingulata) and cotton, Grainstaining complex on rice, black rot of grape bacterium on grapevine (Guignardia bidwellii) (black rot), Rust on rosaceous plant and Chinese juniper (Gymnosporangium), for example G.sabinae on pears (rust of pear), Helminthosporium on corn, Cereal and rice (Helminthosporium) (synonym Drechslera (Drechslera), epigamous: cochliobolus belongs to), camel spore Rust (Hemileia), for example coffee rust on coffee (H.vastatrix) (coffee leaf rust), foxiness on grapevine is intended Isaria (Isariopsis clavispora) (synonym Cladosporium vitis), Kidney bean shell ball spore on soybean and cotton (Macrophomina phaseolina (synonym phaseoli)) (root rot/stem rot), for example, the withered bacterium of the mould leaf of snow (Microdochium (synonym Fusarium) nivale (snow mold) on Cereal (wheat or barley), diffusion cross hair shell (Microsphaera diffusa) (powdery mildew) on soybean, Monilia (Monilinia), for example drupe chain sclerotinia sclerotiorum (M.laxa), peach brown rot fungus (M.fructicola) and the M.fructigena on drupe and other rosaceous plants (blossom rot and branch maize ear rot, brown rot), mycosphaerella on Cereal, banana, berry and peanut (Mycosphaerella), the Fijian ball chamber bacterium (M.fijiensis) (Sigatoka black spot) on the standing grain green-ball chamber bacterium (M.graminicola) on wheat (phorozoon: wheat septoria (Septoria tritici), septoria musiva leaf spot) or banana for example, for example, for example, for example, for example, Peronospora (Peronospora) (downy mildew) on cabbage (rape downy mildew (P.brassicae)), rape (parasitic downy mildew (P.parasitica)), bulb plant (shallot downy mildew (P.destructor)), tobacco (tobacco downy mildew (P.tabacina)) and soybean (downy mildew bacterium (P.manshurica)), yam bean layer rest fungus (Phakopsora pachyrhizi) and mountain horseleech layer rest fungus (P.Meibomiae) (soybean rust) on soybean, for example, for example, Phialophora (Phialophora) on grapevine (P.Tracheiphila and P.tetraspora) and soybean (brown stem rot bacterium (P.gregata): stem disease evil) for example, black shin stem on rape and cabbage is selected the beet stem point mould (P.betae) (root rot, leaf spot and damping-off) on mould (Phoma lingam) (root rot and stem rot) and sugar beet, sunflower, grapevine (for example black rot of grape bacterium (P.viticola): can spot and leaf spot) and soybean (stem rot: P.phaseoli for example, epigamous: the Phomopsis (Phomopsis) soybean north stem canker (Diaporthe phaseolorum)), maize brown spot bacterium on corn (Physoderma maydis) (brown spot), each Plants for example, for example, as green pepper and cucumber kind (Phytophthora capsici (P.capsici)), soybean (soybean phytophthora (P.megasperma), late blight) and for example, Phytophthora (Phytophthora) (droop on broad leaf tree (robur sudden death pathogen (P.ramorum): Oak Tree is anxious dead sick) synonym P.sojae), potato and tomato (phytophthora infestans (P.infestans) for example:, root rot, leaf rot, fruit maize ear rot and stem rot), plasmodiophora brassica bacteria on cabbage, rape, radish and other plant (Plasmodiophora brassicae) (clubroot), Peronospora (Plasmopara), for example the grape on grapevine is given birth to the Plasmopara Halstedll (P.halstedii) on single shaft mould (P.viticola) (grapevine downy mildew) and sunflower, Podosphaera on rosaceous plant, hops, a kind of fruit, such as apple, pear, etc. and berry (Podosphaera) (powdery mildew), for example the apple mildew bacterium (P.leucotricha) on apple, the virus disease that Cereal belongs to (Polymyxa) and propagates thus as the many Acarasiales on barley and wheat (Polymyxa Graminis (P.graminis)) and sugar beet (Polymyxa betae (P.betae)), Cereal is as wheat-based maize ear rot bacterium (Pseudocercosporella herpotrichoides) (eye spot, epigamous: Tapesia yallundae) on wheat or barley, Pseudoperonospora on each Plants (Pseudoperonospora) (downy mildew), for example the humulus false frost of grass (P.humili) on the false downy mildew (P.cubensis) of the Cuba on Cucumis or hops, Pseudopezicula tracheiphila on grapevine (red fire disease or grape angle spot leaf scorch, phorozoon: Saksenaea (Phialophora)), Puccinia on each Plants (Puccinia) (rust), for example Cereal is as wheat, wheat handle rest fungus (P.triticina) (leaf rust or leaf rust) on barley or rye, bar shaped handle rust (P.striiformis) (stripe rust or yellow rust), barley handle rust (P.hordei) (barley yellow dwarf leaf rust), puccinia graminis (P.graminis) (stem rust or stalk rust) or puccinia triticinia (P.recondita) (leaf rust or leaf rust), Asparagus handle rust (P.asparagi) on Puccinia kuehnii on sugarcane (P.kuehnii) and asparagus, wheat yellow blothch bacterium on wheat (Pyrenophora (phorozoon: Drechslera) tritici-repentis) the navel spore (P.teres) (net blotch) of wriggling in the barley filigree on (maculopathy) or barley, Pyricularia Sacc. (Pyricularia), for example piricularia oryzae (P.grisea) on the Pyricularia oryzae on rice (P.oryzae) (epigamous: Magnaporthe grisea, rice blast) and lawn and Cereal, for example, pythium (Pythium) (damping-off) on lawn, rice, corn, wheat, cotton, rape, sunflower, soybean, sugar beet, vegetables and various other plant (Pythium ultimum bacterium (P.ultimum) or melon and fruit corruption mould (P.aphanidermatum)), Ramularia (Ramularia), for example the beet leaf spot fungi (R.Beticola) on the R.collo-cygni on barley (post every the spore leaf spot, physiology leaf spot) and sugar beet, Rhizoctonia (Rhizoctonia) on cotton, rice, potato, lawn, corn, rape, potato, sugar beet, vegetables and various other plant, the Rhizoctonia solani Kuhn on soybean (R.solani) (root rot and stem rot) for example, the Rhizoctonia cerealis (R.Cerealis) (wheat sharp eyespot) on the R.solani on rice (banded sclerotial blight) or wheat or barley, Rhizopus stolonifer on strawberry, carrot, cabbage, grapevine and tomato (Rhizopus stolonifer) (black points, soft rot), rye beak spore (Rhynchosporium secalis) (leaf spot) on barley, rye and triticale, rice broom branch on rice mould (Sarocladium oryzae) and S.attenuatum (sheath rot disease), vegetables and field crop for example, for example, as the Sclerotinia (Sclerotinia) (stem rot or white mould) on rape, sunflower (sclerotinite (S.sclerotiorum)) and soybean (S.Rolfsii or S.sclerotiorum), Septoria on each Plants (Septoria), the soybean septoria musiva (S.glycines) (brown spot) on soybean for example, the many spores of the withered shell of grain husk on the wheat septoria on wheat (S.tritici) (septoria musiva leaf spot) and Cereal (S. (synonym Stagonospora) nodorum) (leaf blight and spot blight), grape snag shell on grapevine (Uncinula (synonym Erysiphe) necator) (powdery mildew, phorozoon: Oidium tuckeri), for example, leaf blight Pseudomonas (Setospaeria) (leaf spot) on corn (Exserohilum turcicum (S.turcicum), the large spot Exserohilum of synonym (Helminthosporium turcicum)) and lawn, head smut), the axle Ustilago (Sphacelotheca) (smut) on Chinese sorghum and sugarcane corn (silk axle smut (S.reiliana) for example:, monofilament shell powdery mildew (Sphaerotheca fuliginea) (powdery mildew) on cucumber, powder scab bacterium (Spongospora subterranea) (powdery scab) on potato and the virus disease of propagating thus, Stagonospora on Cereal (Stagonospora), the many spores of the withered shell of the grain husk on wheat (S.nodorum) (leaf blight and spot blight, epigamous: clever withered ball chamber bacterium (Leptosphaeria[synonym Phaeosphaeria] nodorum)) for example, synchytrium endobioticum percival on potato (Synchytrium endobioticum) (potato canker), Exoascus (Taphrina), for example lopsided external capsule bacterium (T.Deformans) (leaf-curl) on peach and Lee's external capsule bacterium (T.pruni) (cystocarp Lee) on Lee, Thiclaviopsis on tobacco, a kind of fruit, such as apple, pear, etc., vegetables, soybean and cotton (Thielaviopsis) (black root rot), for example black root rot bacterium (T.basicola) (synonym Chalara elegans), Tilletia on Cereal (Tilletia) (bunt or the bunt smut of wheat), for example T.tritici on wheat (synonym T.caries, the bunt of wheat) and T.controversa (dwarf bunt), meat spore core coral bacterium (Typhula incarnata) (grey snow mold) on barley or wheat, Ustilago (Urocystis), for example hidden the smut (U.occulta) (bar smut) on rye, vegetables for example, for example, belong to (Uromyces) (rust) as the rust of the monospore on Kidney bean (wart top uromyce (U.appendiculatus), synonym U.phaseoli) and sugar beet (rust of beet (U.betae)), Cereal (for example wheat loose smut (U.nuda) and U.avaenae), smut of maize) and the Ustilago on sugarcane (Ustilago) (smut) corn (Ustilago maydis (U.maydis) for example:, for example, Venturia (Venturia) (scab) on apple (scab of apple (V.inaequalis)) and pears, and each Plants if tree and view and admire the Verticillium (Verticillium) (leaf branch droop) on tree, grapevine, berry, vegetables and field crop, for example the eggplant verticillium wilt pathogen (V.dahliae) on strawberry, rape, potato and tomato.

Mixture of the present invention also is suitable for for example, preventing and treating fungal disease in material (timber, paper, paint dispersion, fiber or fabric) protection and stored prod protection.Term " material protection " is interpreted as referring to safeguard industries and non-living material as adhesive, glue, timber, paper and cardboard, textile, leather, paint dispersion, plastics, cooling lubricant, fiber and fabric in order to avoid harmful microorganism is attacked and destroyed as fungus and bacterium.With regard to timber and other materials protection, should note following harmful fungoid especially: the Ascomycetes fungi, for example line mouth shell belongs to (Ophiostoma), long beak shell belongs to (Ceratocystis), Aureobasidium pullulans (Aureobasidium pullulans), Sclerophoma genus, Chaetomium (Chaetomium), Humicola (Humicola), Peter's shell genus (Petriella), the mould genus of pieces (Trichurus); The Basidiomycetes fungi, for example cellar fungus belongs to (Coniophora), Coriolus Qu61 (Coriolus), sticky gill fungus genus (Gloeophyllum), Lentinus (Lentinus), Pleurotus (Pleurotus), hole genus (Poria), Merulius (Serpula) and Tyromyces (Tyromyces) crouch; Partly know the guiding principle fungi; for example aspergillus (Aspergillus), Cladosporium (Cladosporium); Penicillium (Penicillium), trichoderma (Trichoderma), Alternaria (Alternaria), paecilomyces (Paecilomyces) and Zygomycetes fungi; for example mucor (Mucor), should note following yeast fungus in this external stored prod protection: candida (Candida) and saccharomyces cerevisiae (Saccharomyces cerevisae).

Generally speaking, " antifungal effective dose " means to obtain the Observable effect to growth, comprises necrosis, death, delays, prevents and remove, destroys or reduce occurring and the amount of mixture of the present invention that the active effect of target organism is required or the composition that comprises described mixture.Antifungal effective dose each mixtures/combinations can be according to the present invention used changes.The mixtures/combinations of antifungal effective dose also can be according to the dominance condition variation such as fungicidal effect and duration, weather, target species, place, mode of administration as required.

Mixture of the present invention is for a large amount of harmful fungoids or insect particular importance on the crop material control various cultivated plants, plant propagation material and these plants, described plant is for example Cereal, for example wheat, rye, barley, triticale, oat or rice; Beet, for example sugar beet or fodder beet; Fruit, as a kind of fruit, such as apple, pear, etc., drupe or berry, for example apple, pears, Lee, peach, almond, cherry, strawberry, raspberry, blackberry, blueberry or dayberry; Leguminous plant, for example French beans, pea, clover or soybean; Oil plants, for example rape, leaf mustard, olive, sunflower, coconut, cocoa bean, castor oil plant, oil palm, peanut or soybean; Cucurbitaceous plant, for example pumpkin, cucumber or muskmelon; Fibre plant, for example cotton, flax, hemp or jute; Cedra fruits, for example orange, lemon, grapefruit or tangerine; Vegetables, for example spinach, lettuce, asparagus, cabbage, carrot, onion, tomato, potato, cucurbit or green pepper; Bay class plant, for example avocado, Chinese cassia tree or camphor; Energy and material plant, for example corn, soybean, rape, sugarcane or oil palm; Corn; Tobacco; Nut; Coffee; Tea; Banana; Grape vine (table grapes and must grape vine); Lupulus; Lawn; Stevia (also referred to as Stevia); Natural rubber plant or view and admire and forest plants, for example flowers, shrub, broad-leaved tree and evergreen tree are as coniferous tree; Described plant propagation material is for example seed.

Preferably mixture of the present invention is used for preventing and treating field crops as potato, sugar beet, tobacco, wheat, rye, barley, oat, rice, corn, cotton, soybean, rape, leguminous plant, sunflower, coffee or sugarcane; Fruit; Grape vine; Ornamental plants; Or vegetables are as cucumber, tomato, a large amount of fungies on Kidney bean or pumpkin.

Preferably will use mixture of the present invention to be used for preventing that Cereal is as wheat, rye, barley or oat to the processing of plant propagation material; A large amount of fungus bodies on rice, corn, cotton and soybean.

In particularly preferred embodiments, the invention further relates to a kind of method of preventing and treating the plant pathogenic fungi on rice, it comprises mixture of the present invention preferably is applied to this mixture in paddy field, and it comprises by defined mixture process of the present invention above.

For the especially preferred mixture of this purpose, be mentioned above those, especially, most preferred mixture comprises as pyraclostrobin Compound I I and the Fungicidal compounds I that is selected from kasugarnycin, carpropamide, two chlorine zarilamids, wherein preferably, the weight ratio of each mixture that comprises Fungicidal compounds I and Fungicidal compounds II is 1:500-500:1, be preferably 1:100-100:1, more preferably 1:25-25:1, most preferably be 1:10-10:1.

Preferably, the plant pathogenic fungi on rice comprises above-mentioned fungi, and additionally comprises other kinds in rice: the Alternaria on rice (Alternaria), Bipolaris (Bipolaris) (for example rice Bipolaris (Bipolaris oryzae)), Drechslera on rice (Drechslera), rice tail spore (Cercospora oryzae), palace section cochliobolus (Cochliobolus miyabeanus), curvularia lunata (Curvularia lunata), rice broom branch mould (Sarocladium oryzae), S attenuatum, rice leaf smut (Entyloma oryzae), Fusarium (Fusarium) is as fusarium semitectum (Fusarium semitectum) (and/or moniliforme Gibberella fujikuroi (bakanae disease), Gram’s staining complex (various pathogene) and/or pythium (Pythium), Helminthosporium (Helminthosporium) spore (Helminthosporium oryzae) of wriggling as long as rice, Xanthomonas oryzae (Microdochium oryzae), Pyricularia oryzae (Pyricularia grisea (synonym Pyricularia oryzae)), the Pellicularia sasakii in rice), Rhizoctonia solani Kuhn (Corticium sasakii) and rice false smut (Ustilaginoidea virens) Rhizoctonia (Rhizoctonia) is as Rhizoctonia solani Kuhn (Rhizoctonia solani) (synonym:.

In the more preferred of the plant pathogenic fungi method in described control paddy field, described plant pathogenic fungi is Pyricularia oryzae (Pyricularia grisea (synonym Pyricularia oryzae)) and/or Rhizoctonia (Rhizoctonia), especially Rhizoctonia solani Kuhn (Rhizoctonia solani) (synonym: the Pellicularia sasakii in rice).

In the method for fungi on above-mentioned control rice, the amount of fungicide is generally 20/500g/ha.

As mentioned above, a kind of method of improving plant health is contained in the present invention, wherein with the described plant of mixture process of the present invention of plant health effective dose, wherein growth or expection growth have the place of described plant or grow the plant propagation material of described plant by it.

Term " plant health effective dose " refers to is enough to obtain the hereinafter amount of the mixture of the present invention of defined plant health effect.Hereinafter will provide more exemplary information about amount, method of application and proper ratio used.In a word, those skilled in the art know that this amount can change in wide region and it depends on various factors cultivated plant or material and this fact of weather conditions as processed.

Determine as the case may be, term " plant health effective dose " and/or " antifungal effective dose " contained in term " effective dose ".

" place " means conk wherein maybe can grow plant, plant propagation material (preferred seed), soil, zone, material or the environment of fungi.

When the described mixture of preparation, preferably use pure reactive compound, can add wherein the reactive compound of other pest controls as required, as the compound of Insecticides (tech) & Herbicides (tech), fungicide or weeding or growth regulating-activity or fertilizer as other active components.

Mixture of the present invention processes fungi by the reactive compound by the antifungal effective dose or to be protected in order to avoid the plant of fungal attack, plant propagation material (preferred seed), material or soil are used.Use and can carry out before or after described material, plant or plant propagation material (preferred seed) are by fungal infection.

Preferably, mixture of the present invention is processed fungi by the reactive compound by the antifungal effective dose via foliage applying or to be protected in order to avoid the plant of fungal attack or soil are used.Now, use also and can carry out before described plant is by fungal infection and afterwards.

In the method for control harmful fungoid, depend on type of compounds and required effect, the rate of application of mixture of the present invention is 0.1-10000g/ha, preferred 2-2500g/ha, more preferably 5-1000g/ha, most preferably 10-750g/ha, be in particular 20-500g/ha.

For the present invention, term " plant " refers to plant integral body, the part of plant or the propagating materials of plant.

The plant of available mixture process of the present invention and the propagating materials of described plant comprise plant or the genetically modified plants of all genetic modifications, the crop of herbicide-tolerant or fungicide or insecticide effect due to the breeding that comprises gene engineering method for example, or compare the plant with modification characteristic with existing plant, it for example can and/or produce mutant and/or produce by the restructuring program by traditional breeding way.

For example, also mixture of the present invention can be used (as seed treatment, spraying process, ditch dug with a plow is processed or by any other mode) to by the plant of breeding, mutagenesis or gene engineering method modification, include but not limited to list marketing or develop total agricultural biotechnologies product (referring to http://www.bio.org/speeches/pubs/er/agri_products.asp).Genetically modified plant is that its genetic material is by being used recombinant DNA technology to be difficult under field conditions (factors) the plant of modifying by the mode of hybridizing, suddenling change or restructuring obtaining naturally.Usually by one or more gene integrations in the genetic material of genetically modified plant to improve some performance of described plant.This genoid is modified the target posttranslational modification that also includes but not limited to protein, oligopeptides or polypeptide, for example by glycosylation or polymer addition as isoprenylation, acetylization or farnesylation structure division or PEG structure division.

Due to breeding or engineered conventional method, for example give the plant of modifying by breeding, mutagenesis or gene engineering with the tolerance of using to the particular category weed killer herbicide, described weed killer herbicide as the plant auxins weed killer herbicide as dicamba (dicamba) or 2,4-drips (2,4-D), bleaching agent class weed killer herbicide is as medical midbodies of para (ortho)-hydroxybenzoic acetone acid dioxygenase enzyme (HPPD) inhibitor or phytoene desaturase (PDS) inhibitor; Acetolactate synthestase (ALS) inhibitor is as sulfonylurea or imidazolone type, and enol pyruvylshikimate 3-phosphate synthase (EPSPS) inhibitor is as glyphosate (glyphosate); Glutamine synthelase (GS) inhibitor is as careless ammonium phosphine (glufosinate); The protogen IX oxidase inhibitor; The lipoid biosynthesis inhibitor is as acetyl CoA carboxylase (ACC enzyme) inhibitor; Or cyanophenyl class (oxynil) weed killer herbicide (for example Brominal (bromoxynil) or ioxynil (ioxynil)).In addition, also by several genes, modify and make the multiple weed killer herbicide classification of Plant Tolerance, for example tolerate glyphosate and careless ammonium phosphine the two or tolerance glyphosate and another kind of weed killer herbicide as ALS inhibitor, HPPD inhibitor, plant auxins weed killer herbicide or ACC enzyme inhibitor the two.These herbicide tolerant technology for example are described in Pest Managem.Sci.61,2005,246; 61,2005,258; 61,2005,277; 61,2005,269; 61,2005,286; 64,2008,326; 64,2008,332; Weed Sci.57,2009,108; Austral.J.Agricult.Res.58,2007,708; Science316,2007,1185 reach in the document of wherein quoting.By the conventional method of breeding (mutagenesis), give several cultivated plants with the tolerance to weed killer herbicide, as tolerated imidazolone type as imazamox (imazamox)

rape in summer (Canola, German BASF SE) or tolerance sulfonylurea are as tribenuron-methyl (tribenuron)

sunflower (DuPont, USA).Use gene engineering method give cultivated plant as soybean, cotton, corn, beet and rape with the tolerance as glyphosate or careless ammonium phosphine to weed killer herbicide, wherein some can be with trade name

(tolerance glyphosate, U.S. Monsanto), (tolerance imidazolone, German BASF SE) and

(tolerating careless ammonium phosphine, German Bayer CropScience) is commercially available.

In addition, also contain the plant that can synthesize one or more insecticidal proteins by using recombinant DNA technology, this albumen is known those by bacillus (Bacillus) bacterium especially, bacillus thuringiensis (Bacillus thuringiensis) particularly, for example delta-endotoxin is as CryIA (b), CryIA (c), CryIF, CryIF (a2), CryIIA (b), CryIIIA, CryIIIB (b1) or Cry9c; Asexual insecticidal proteins (VIP) is as VIP1, VIP2, VIP3 or VIP3A; Nematode is settled down the insecticidal proteins of bacterium as Photobacterium (Photorhabdus) or Xenorhabdus (Xenorhabdus); The toxin that animal produces is as scorpion toxin, spider toxin, wasp toxin or other insect-specific neurotoxins; Mycetogenetic toxin is as streptomyces (Streptomycetes) toxin; Phytolectin is as pea or barley lectin element; Agglutinin; Protease inhibitors is as trypsin inhibitor, serpin, patatin, cystatin or antipain; Ribosome inactivating protein (RIP) is as ricin (WA), corn RIP, abrin, Seeds of Luffa cylindrica albumen, saporin or different strain diarrhoea toxalbumin (bryodin); The steroid metabolism enzyme is as 3-hydroxy steroid oxidase, ecdysteroids-IDP glycosyl transferase, cholesterol oxidase, moulting hormone inhibitor or HMG-CoA reductase; The ion channel blocking agent is as sodium channel or calcium channel blocker; Juvenile hormone esterase; Diuretic hormone acceptor (helicokinin acceptor); The Stilbene synzyme, bibenzyl synzyme, chitinase or dextranase.For the present invention, these insecticidal proteins or toxin also specifically are interpreted as front toxin, hybrid protein, albumen brachymemma or other aspect modifications.Hybrid protein is characterised in that the novel combination (for example, referring to WO02/015701) in albumen territory.Other examples that this toxoid maybe can synthesize this anatoxic genetically modified plant for example are disclosed in EP-A374753, WO93/007278, WO95/34656, EP-A427529, EP-A451878, WO03/18810 and WO03/52073.The method of producing such genetically modified plant is well-known to those skilled in the art and for example is described in above-mentioned publication.In genetically modified plant, contained these are given containing insecticidal proteins the plant that produces these albumen and be take to being insect, especially beetle (coleoptera (Coleoptera)), dipteral insect (diptera (Diptera)) and the moth (Lepidoptera (Lepidoptera)) of arthropods insect and the tolerance of nematode (Nematoda (Nematoda)) on all taxonomy.The genetically modified plant that can synthesize one or more insecticidal proteins for example is described in above-mentioned publication, the commercially available acquisition of some in them, for example (producing the corn variety of toxin C ry1Ab),

plus (producing the maize culture kind of toxin C ry1Ab and Cry3Bb1),

(producing the maize culture kind of toxin C ry9c),

rW (producing the maize culture kind of toxin C ry34Ab1, Cry35Ab1 and enzyme phosphinothricin-N-acetyl-transferase [PAT]),

33B (producing the cotton culture kind of toxin C ry1Ac),

i (producing the cotton culture kind of toxin C ry1Ac),

iI (producing the cotton culture kind of toxin C ry1Ac and Cry2Ab2),

(producing the cotton culture kind of VIP toxin),

(producing the potato cultivar of toxin C ry3A),

bt11 (for example

cB) and the Bt176 of French Syngenta Seeds SAS (producing the maize culture kind of toxin C ry1Ab and PAT enzyme), the MIR604 of France Syngenta Seeds SAS (produces the maize culture kind of the modification translation of toxin C ry3A, referring to WO03/018810), the MON863 (producing the maize culture kind of toxin C ry3Bb1) of Belgium Monsanto Europe S.A., the IPC531 (producing the cotton culture kind of the modification translation of toxin C ry1Ac) of Belgium Monsanto Europe S.A. and 1507 (the producing the maize culture kind of toxin C ry1F and PAT enzyme) of Belgian Pioneer Overseas Corporation.

In addition, also contain and can synthesize one or more albumen by using recombinant DNA technology to improve the plant of plant to resistance or the tolerance of bacterium, virus or fungal pathogens.The example of this plastein is so-called " albumen relevant to pathogenesis " (PR albumen, for example, referring to EP-A392225), Plant Genes Conferring Resistance To Pathogens (for example expressing the potato cultivar for the resistant gene of the phytophthora infestans (Phytophthora infestans) from wild Mexico potato Solanum bulbocastanum) or T4 Lysozyme (for example can synthesize and bacterium be strengthened to the potato cultivar of these albumen of resistance as Erwinia amylvora has).The method of producing this genoid modified plant is that those skilled in the art know and for example are described in above-mentioned publication.

In addition, also contain and can synthesize one or more albumen by using recombinant DNA technology for example, to improve output (yield of biomass, Grain Yield, content of starch, oil content or protein content), to the tolerance of the environmental factor of arid, salinity or other limiting growths or to the plant of the tolerance of the insect of plant and fungi, bacterium or viral pathogen.

In addition, also contain by using recombinant DNA technology to contain the content of material of the amount of changing or novel substance content especially to improve the mankind or zootrophic plant, (for example for example produce the oil crop of sanatory long-chain omega-fatty acid or unsaturated ω-9 fatty acid

rape, Canadian DOW Agro Sciences).

In addition, also contain by using recombinant DNA technology contain the content of material of the amount of changing or novel substance content especially to improve the plant of raw material production, for example produce the raising amount amylopectin potato (for example

potato, German BASF SE).

In other embodiments of the present invention, root and spray by mixture of the present invention for the protection of seed and seedling, preferred seed.

Seed treatment can be carried out in plantation to land for growing field crops in seed-box.

With regard to seed treatment, the weight ratio in mixture of the present invention depends on the compound property of mixture of the present invention usually.

Especially the composition that can be used for seed treatment is for example:

The A solubility concentrates thing (SL, LS)

D emulsion (EW, EO, ES)

E suspension (SC, OD, FS)

F water-dispersible granule and water-soluble granular (WG, SG)

G water dispersible pow-ders and water-soluble powder (WP, SP, WS)

H gel formulation (GF)

But I dusting powder (DP, DS)

These compositions can or be applied to plant propagation material without dilution through dilution, particularly on seed.These compositions can or be applied to plant propagation material without dilution through dilution, particularly on seed.Described composition provides the 0.01-60 % by weight after diluting 2-10 times in the instant preparation, preferably the active material concentration of 0.1-40 % by weight.Use can the sowing before or among carry out.Agrochemistry compound and composition thereof are applied to respectively to plant propagation material, especially seed or to use the method for its treatment of plant propagation material, especially seed be known in the art and comprise seed dressing, dressing, granulation, dusting and the immersion application process (having ditch dug with a plow to process) of described propagating materials.In preferred embodiments, by not bringing out the method for sprouting, for example by seed dressing, granulation, dressing and dusting, respectively described compound or its composition are applied on plant propagation material.

In the processing of plant propagation material (preferred seed), the rate of application of mixture of the present invention is usually for the product (usually comprising the 10-750g/l active substance) through preparation.

The invention still further relates to the breeding product of plant, especially seed, it comprises, and dressing has and/or the composition of the mixture that contains defined mixture above or contain two or more active components or two or more provide the mixture of the composition of one of active component separately.Described plant propagation material (preferred seed) is with 0.1g-10kg/100kg plant propagation material (preferred seed), and preferably the amount with 0.1g-1kg/100kg plant propagation material (preferred seed) comprises mixture of the present invention.

For example, the weight ratio of Compound I I is preferably 0.5-200g/100kg plant propagation material (preferred seed) herein, more preferably 1-50g/100kg plant propagation material (preferred seed), most preferably 1-20g/100kg plant propagation material (preferred seed).

For example, the weight ratio of Compound I is preferably 1-2000g/100kg plant propagation material (preferred seed) herein, more preferably 1-1000g/100kg plant propagation material (preferred seed), most preferably 25-750g/100kg plant propagation material (preferred seed), most preferably 50-500g/100kg plant propagation material (preferred seed).

The compound of mixture of the present invention separately or co-administered by before or after plant seeding or before or after plant emerges by seed, rice shoot, plant or soil spraying or dusting are carried out.

Further set forth the present invention by embodiment hereinafter, yet the present invention is not limited by the examples.

Embodiment 1-on wheat by the activity of the caused leaf spot blight of wheat septoria (Septtr)

According to ratio, liquid storage is mixed, suction moves to titer plate (MTP) and goes up and be diluted with water to described concentration.Then the spore suspension of wheat septoria is added in biomalt or yeast-bacto peptone-glycerine water solution.Described plate is placed in to the steam-laden chamber at the temperature of 18 ° of C.Use absorption spectrophotometry, measure MTP in inoculation after 7 days in the 405nm place.

The results are shown in following table 1.By record parameter with not containing the growth (100%) of the scheme that contrasts of active substance with containing fungi and do not contain the relative growth (with %) of blank value comparison to measure the pathogene in each reactive compound of reactive compound.The Expected Results of active compound combinations is used Colby formula [R.S.Colby, " Calculating synergistic and antagonistic responses of herbicide combinations ", Weeds15,20-22 (1967)] determine and with the observation effect relatively and the synergistic function of proved invention mixture.

Table 1

*) according to Colby

Claims (13)

1. mixture, it is usingd the Synergistic effective dose and comprises following compound as active component:

1) a kind ofly be selected from following Fungicidal compounds I: kasugarnycin (kasugamycin), carpropamide (carpropamid), two chlorine zarilamids (dicyclomet), tricyclazole (tricyclazol), the third oxygen goes out and embroiders amine (mepronil), tecloftalam (tecloftalam), thifluzamide (thifluzamide), fluorine mepanipyrim (diflumetorim), binapacryl (binapacryl), dinobuton (dinobuton), ferimzone (ferimzone), Bitertanol (bitertanol), alkene azoles alcohol (diniconazol-M), acid amides azoles (imiben-conazol), simeconazoles (simeconazol), pefurazoate (pefurazoate), piperazine, nuarimol (nuarimol), pyrifenox (pyrifenox), triforine (triforin), aldimorph, dodemorfe acetic acid esters (dodemorphacetat), pipron (piperalin), different thiophene bacterium ketone (octhilinon),

quinoline acid

the mould prestige of second (diethofencarb), Pencycuron (pencycuron), fluopicolide (fluopicolide), pyriofenon, blasticidin-S (blasticidin-S), midolthromycin (mildiomycin), streptomycin (streptomycin), terramycin (oxytetracyclin), jinggangmeisu (validamycin A), ethofumesate (fluoroimid), Hinosan (edifenphos), iprobenfos (iprobenfos), Ppyrazophos (pyrazophos), Isoprothiolane (isoprothiolane), botran (dicloran), pcnb (quintozene), tecnazene (tecnazen), tolelofos-methyl (tolclofos-methyl), biphenyl (biphenyl), kobam (etridiazol), flumorph (flumorph), ferbam (ferbam), metham-sodium (metam), anilazine (anilazin), Euparen (dichlofluanid), antiphen (dichlorophen), flusulfamide (flusulfamid), guazatine (guazatin), biguanides acetate (guazatin-acetat), valida (validamycin), Polyoxin (polyoxin B), pyroquilon (pyroquilon), tiadinil (tiadinil), bronopol (bronopol), chinomethionat (chinomethionat), two ethoxy imidazoles prestige (debacarb), diclomezine (diclomezin), benzene enemy fast (difenzoquat), benzene opposes fast methylsulfuric acid ester (difenzoquatmethylsulfat), diphenylamines (diphenylamin), fluorine biphenyl bacterium (flumetover), flusulfamide (flusulfamid), methasulfocarb (methasulfocarb), N-Serve (nitrapyrin), isopropyl disappear (nitrothal-isopropyl), the third oxygen quinoline (proquinazid), tebufloquin, tecloftalam (tecloftalam) and azoles bacterium piperazine (triazoxid), with

2) as the pyraclostrobin (pyraclostrobin) of Compound I I.

2. according to the mixture of claim 1, wherein Compound I is selected from kasugarnycin (kasugamycin), carpropamide (carpropamid), two chlorine zarilamid (dicyclomet) and tricyclazole (tricyclazol).

3. according to the mixture of claim 1, wherein Compound I is selected from kasugarnycin (kasugamycin), carpropamide (carpropamid) or two chlorine zarilamid (dicyclomet).

4. according to the mixture of any one in claim 1-4, wherein the weight ratio of Compound I: II is 1:500-500:1.

5. according to the mixture of any one in claim 1-4, wherein the weight ratio of Compound I: II is 1:100-100:1.

6. according to the mixture of any one in claim 1-4, wherein the weight ratio of Compound I: II is 1:10-10:1.

7. a Fungicidal composition, it comprises the liquid or solid carrier and according to the defined mixture of any one in claim 1-6.

8. a method of preventing and treating fungi, wherein with fungi, its habitat, breeding ,Qi place, place or to be protected in order to avoid the plant of fungal attack, soil or plant propagation material as described in the mixture process as defined as any one in claim 1-7 of effective dose.

9. method according to Claim 8, wherein said method comprises the plant pathogenic fungi on the control rice.

10. according to the method for claim 9, wherein said method comprises by using according to the plant pathogenic fungi in the mixture control paddy field of any one in claim 1-7.

11. a protective plant propagating materials avoids the method for fungi, comprises and makes contacting according to the defined mixture of any one in claim 1-7 of described plant propagation material and antifungal effective dose.

12. the method for any one in a kind according to Claim 8-12, wherein will according to the defined compound of any one in claim 1-7 simultaneously, combine or separate, or use successively.

13. plant propagation material, its amount with the 0.01g-10kg/100kg plant propagation material comprises according to the defined mixture of any one in claim 1-7.