CN103230562A - Traditional Chinese medicine formula for nourishing kidney and activating intestines and preparation method thereof - Google Patents
Traditional Chinese medicine formula for nourishing kidney and activating intestines and preparation method thereof Download PDFInfo
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- CN103230562A CN103230562A CN2013101548790A CN201310154879A CN103230562A CN 103230562 A CN103230562 A CN 103230562A CN 2013101548790 A CN2013101548790 A CN 2013101548790A CN 201310154879 A CN201310154879 A CN 201310154879A CN 103230562 A CN103230562 A CN 103230562A
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Abstract
The invention discloses a traditional Chinese medicine formula for nourishing kidney and activating intestines and a preparation method thereof. The traditional Chinese medicine formula comprises the following raw material medicines in parts by weight: 2-4 parts of rehmanniae praeparatum, 1-3 parts of fructus lycii, 1-3 parts of radix codonopsis, 1-3 parts of rhizoma dioscoreae, 1-3 parts of pericarpium arecae, 0.5-1.5 parts of cortex magnoliae officinalis, 0.5-1.5 parts of fructus amomi and 0.5-1.5 parts of radix aucklandiae. The traditional Chinese medicine formula disclosed by the invention realizes functions of nourishing kidney and strengthening spleen and regulating qi movement, and effectively improves the symptoms such as lack in desire to defecate, difficult start to defecate, reduction of defecating frequency, abdominal distension and the like caused by spleen and kidney deficiency and unsmooth qi movement.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to Chinese medicine formula of a kind of nourishing kidney fortune intestinal and preparation method thereof.
Background technology
Constipation has had a strong impact on people's quality of life as a kind of sub-health state, and plays an important role in diseases such as colon cancer, hepatic encephalopathy, presenile dementia.According to the series diagnosis standard of Rome functional gastrointestinal disorder, chronic constipation is divided into slow-remove type (STC), outlet obstructed type (OOC) and mixed type again, and wherein STC is wherein common type.
Chronic slow-transit constipation (STC) is clinical common persistent ailment, and due to illness because of complexity, pathogenesis is still not exclusively clear, and difficult diagnosis is the difficult problem in the clinical treatment always.Modern medicine adopts Grading treatment, adopts western medicine more, but because how undesirable the Western medicine curative effect is, and contraindication and complication are more, finally seek help from operation, but operation belongs to and has wound therapy, patient generally to be difficult to accept.Therefore seek Chinese medicine slowly the property transmitted constipation have the important clinical meaning.
Summary of the invention
Purpose of the present invention is exactly at above-mentioned defective of the prior art, but provides a kind of nourishing kidney intestine moistening of pure Chinese medicine preparation, effectively treat the Chinese medicine formula of constipation.
To achieve these goals, technical scheme provided by the invention is: a kind of Chinese medicine formula of nourishing kidney fortune intestinal, described Chinese medicine formula comprises according to following raw materials in weight portion medicine: Radix Rehmanniae 2-4 part, Fructus Lycii 1-3 part, Radix Codonopsis 1-3 part, Rhizoma Dioscoreae 1-3 part, Pericarpium Arecae 1-3 part, Cortex Magnoliae Officinalis 0.5-1.5 part, Fructus Amomi 0.5-1.5 part, Radix Aucklandiae 0.5-1.5 part.
Further, the Chinese medicine formula of above-mentioned a kind of nourishing kidney fortune intestinal, described Chinese medicine formula comprises according to following raw materials in weight portion medicine: 3 parts in the Radix Rehmanniae, 2 parts of Fructus Lyciis, 2 parts of Radix Codonopsis, 2 parts of Rhizoma Dioscoreaes, 2 parts of Pericarpium Arecae, 1 part of Cortex Magnoliae Officinalis, 1 part of Fructus Amomi, 1 part of the Radix Aucklandiae.
Second purpose of the present invention provided the preparation method of the Chinese medicine formula of above-mentioned nourishing kidney fortune intestinal, may further comprise the steps:
1) by the prescription weighting raw materials, add water and soaked 1-2 hour, the addition of water is for exceeding raw material powder 3-5cm;
2) the crude drug soak slow fire boiling that step 1) is obtained 20-30 minute;
3) with step 2) raw material medicinal liquid after decocting filters with cotton yarn, obtains the Chinese medicine of nourishing kidney fortune intestinal.
Further, above-mentioned preparation method, in the described step 1), soak time is 5 hours, the addition of water is for exceeding raw material powder 4cm.
Further, above-mentioned preparation method, described step 2) in, decocting time is 25 minutes.
Beneficial effect of the present invention is: the Chinese medicine formula of a kind of nourishing kidney fortune intestinal provided by the invention, can the nourishing kidney spleen invigorating, regulating functional activities of qi, improve effectively that shortage due to asthenia of both the spleen and kidney, the functional activity of QI being not smooth is just anticipated, diseases such as defecation starts difficulty, the minimizing of the stool frequency, abdominal distention, the property of medicine of its crude drug is as follows:
The Radix Rehmanniae: also be Radix Rehmanniae, the effect that has clearing away heat and cooling blood, tonifying YIN to promote the production of body fluid;
Fructus Lycii: effect is nourishing the liver, nourishing kidney, lung moistening;
Radix Codonopsis: be used for gas Tianjin two and hinder or deficiency of both QI and blood;
Rhizoma Dioscoreae: i.e. Rhizoma Dioscoreae, spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission;
Pericarpium Arecae: have therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, the effect of line water detumescence;
Cortex Magnoliae Officinalis: the circulation of qi promoting removing food stagnancy, dampness is except expiring lowering the adverse QI to relieve asthma;
Fructus Amomi: the removing dampness appetizing, warming spleen and stopping diarrha, it is antiabortive to regulate the flow of vital energy;
The Radix Aucklandiae: in the accent of regulating the flow of vital energy, drying dampness to eliminate phlegm.
Detailed directions is for can be made into oral liquid, concentrated oral liquid, powder, tablet, pill, granule, capsule.
Below be the preparation compliance test result of Chinese medicine formula provided by the invention:
1. clinical data:
MethodsThe cases enrolled 120 examples derive from the clinic case of the court's in June, 2009-2011 year JIUYUE, male 16 examples, women 44 examples; Age 20-76 year, average (51.3 ± 14.1) year; Course of disease 3.5-36, average (4.8 ± 5.2) year; 3-6 days infrequent defecation time, average (4.8 ± 3.2) sky.All cases all meet the diagnostic criteria of chronic functional constipation in the II diagnosis of Rome, meet in following more than 2:
1. the defecation more than 1/4 is required great effort;
2. surpass 1/4 just be firmly or bulk just;
3. not sense to the greatest extent of the defecation more than 1/4;
4. there is during the defecation more than 1/4 anal orifice and rectal intestine to stop up sense;
Need when 5. surpassing 1/4 defecation to help with maneuver;
6. be less than weekly 3 times;
7. get rid of organic constipation and constipation by outlet obstruction person through whole body health check-up and physico-chemical examination.
Colonic transit test 72 hour-symbols things discharge＜80%, and transmission index (label is at the residual number of the residual number/total colectomy of second rectum) (transitindex, TI)＜0.5.All cases are pressed statistics random alignment table numbering by prescription on individual diagnosis precedence, and odd number group is the treatment group, and even number set is matched group, wherein treatment group male 21 examples, women's 39 examples; Matched group male 19 examples, women's 41 examples.Through check, and two groups sex, age, course of disease there was no significant difference (P〉0.05), have comparability.
2. the preparation of " nourishing kidney fortune intestinal side ":
Nourishing kidney fortune intestinal side is made up of the Chinese medicine of nourishing kidney yin, regulating qi-flowing for strengthening spleen based on the design of Chinese medical discrimination typing, totally 8 distinguishes the flavor of, and dosage is followed theory of Chinese medical science " monarch " principle and determined.The common water of prescription drug decocts into medicinal liquid 200ml, filters, packs.Medicinal liquid does not add other additive components.Preservation condition is 4 ℃, and the pot-life is no more than 3.Every day 2 times, 200ml/ time, (medicine) being taken before meal is used sooner or later.Matched group gives mosapride, and every day 3 times, 5mg/ time, taking medicine before meal is used.Be January two groups of courses for the treatment of.
3. criterion of therapeutical effect:
Criterion of therapeutical effect with reference to relevant document constipation is drafted in conjunction with symptom integral.
Recovery from illness: The main symptoms disappears, and stool is normal, and integration 0 minute kept more than 2 weeks.
Produce effects: The main symptoms is obviously improved, and integration preceding reduction for the treatment of reaches 2/3, keeps more than 2 weeks.
Take a turn for the better: The main symptoms takes a turn for the better, and the integration reduction reaches l/2.
Invalid: symptom is not improved, and integration does not have reduction.
4. clinical efficacy:
Treatment group total effective rate is 85%, obviously is better than matched group (68.3%), and two groups of curative effect comparing differences have significance meaning (P〉0.05), and two groups of clinical efficacies are more as shown in table 1.
5. clinical symptoms change:
The variation comparison of defecation cardinal symptom and sign integration before and after the treatment for the treatment of group (
± s) as shown in table 2.Before and after the treatment of every sings and symptoms integration comparing difference all have the significance meaning (
P＜0.05).Treatment postcolon transport test is checked 12 examples, normal 3 examples, 7 examples that take a turn for the better, invalid 2 examples.Untoward reaction such as that patient's period in a medicine does not have is nauseating, vomiting.
It is relatively preceding with treatment,
P＜0.05.
6. colonic transit test result:
It is clear that made spherical radiopaque marker thing develops in human body.Experimental group and matched group 40 routine patients see that all the mark eliminating postpones before the treatment, and 48h mark slip is 20%; The visible experimental group patient 48h mark slip in treatment back is 75%, and matched group 48h mark slip is 60%.
The specific embodiment
Embodiment 1:
A kind of Chinese medicine formula of nourishing kidney fortune intestinal, its crude drug is: 2 parts in the Radix Rehmanniae, 1 part of Fructus Lycii, 1 part of Radix Codonopsis, 1 part of Rhizoma Dioscoreae, 1 part of Pericarpium Arecae, 0.5 part of Cortex Magnoliae Officinalis, 0.5 part of Fructus Amomi, 0.5 part of the Radix Aucklandiae
The preparation method of the Chinese medicine formula of nourishing kidney fortune intestinal may further comprise the steps:
1) by the prescription weighting raw materials, add water and soaked 1 hour, the addition of water is for exceeding raw material powder 3cm, and formula ratio is;
2) the crude drug soak slow fire boiling that step 1) is obtained 20 minutes;
3) with step 2) raw material medicinal liquid after decocting filters with cotton yarn, obtains the Chinese medicine of nourishing kidney fortune intestinal.
Embodiment 2:
A kind of Chinese medicine formula of nourishing kidney fortune intestinal, its crude drug is: 4 parts in the Radix Rehmanniae, 3 parts of Fructus Lyciis, 3 parts of Radix Codonopsis, 3 parts of Rhizoma Dioscoreaes, 3 parts of Pericarpium Arecae, 1.5 parts of Cortex Magnoliae Officinalis, 1.5 parts of Fructus Amomis, 1.5 parts of the Radix Aucklandiae
The preparation method of the Chinese medicine formula of nourishing kidney fortune intestinal may further comprise the steps:
1) by the prescription weighting raw materials, add water and soaked 2 hours, the addition of water is for exceeding raw material powder 5cm, and formula ratio is;
2) the crude drug soak slow fire boiling that step 1) is obtained 30 minutes;
3) with step 2) raw material medicinal liquid after decocting filters with cotton yarn, obtains the Chinese medicine of nourishing kidney fortune intestinal.
Embodiment 3:
A kind of Chinese medicine formula of nourishing kidney fortune intestinal, its crude drug is: 3 parts in the Radix Rehmanniae, 2 parts of Fructus Lyciis, 2 parts of Radix Codonopsis, 2 parts of Rhizoma Dioscoreaes, 2 parts of Pericarpium Arecae, 1 part of Cortex Magnoliae Officinalis, 1 part of Fructus Amomi, 1 part of the Radix Aucklandiae
The preparation method of the Chinese medicine formula of nourishing kidney fortune intestinal may further comprise the steps:
1) by the prescription weighting raw materials, add water and soaked 2 hours, the addition of water is for exceeding raw material powder 4cm, and formula ratio is;
2) the crude drug soak slow fire boiling that step 1) is obtained 25 minutes;
3) with step 2) raw material medicinal liquid after decocting filters with cotton yarn, obtains the Chinese medicine of nourishing kidney fortune intestinal.
It should be noted that at last: the above only is the preferred embodiments of the present invention, be not limited to the present invention, although with reference to previous embodiment the present invention is had been described in detail, for a person skilled in the art, it still can be made amendment to the technical scheme that aforementioned each embodiment puts down in writing, and perhaps part technical characterictic wherein is equal to replacement.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (5)
1. the Chinese medicine formula of nourishing kidney fortune intestinal, it is characterized in that described Chinese medicine formula comprises according to following raw materials in weight portion medicine: Radix Rehmanniae 2-4 part, Fructus Lycii 1-3 part, Radix Codonopsis 1-3 part, Rhizoma Dioscoreae 1-3 part, Pericarpium Arecae 1-3 part, Cortex Magnoliae Officinalis 0.5-1.5 part, Fructus Amomi 0.5-1.5 part, Radix Aucklandiae 0.5-1.5 part.
2. the Chinese medicine formula of intestinal is transported in a kind of nourishing kidney according to claim 1, it is characterized in that described Chinese medicine formula comprises according to following raw materials in weight portion medicine: 3 parts in the Radix Rehmanniae, 2 parts of Fructus Lyciis, 2 parts of Radix Codonopsis, 2 parts of Rhizoma Dioscoreaes, 2 parts of Pericarpium Arecae, 1 part of Cortex Magnoliae Officinalis, 1 part of Fructus Amomi, 1 part of the Radix Aucklandiae.
3. the preparation method of the Chinese medicine composition of nourishing kidney fortune intestinal according to claim 1 and 2 is characterized in that, may further comprise the steps:
1) by the prescription weighting raw materials, add water and soaked 1-2 hour, the addition of water is for exceeding raw material powder 3-5cm;
2) the crude drug soak slow fire boiling that step 1) is obtained 20-30 minute;
3) with step 2) raw material medicinal liquid after decocting filters with cotton yarn, obtains the Chinese medicine of nourishing kidney fortune intestinal.
4. preparation method according to claim 3 is characterized in that, in the described step 1), soak time is 2 hours, and the addition of water is for exceeding raw material powder 4cm.
5. preparation method according to claim 3 is characterized in that, described step 2) in, decocting time is 25 minutes.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1457818A (en) * | 2002-05-16 | 2003-11-26 | 杨文志 | Poison expelling and astheniz resisting balance pill and its preparing method |
| CN101708327A (en) * | 2009-10-27 | 2010-05-19 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating diseases of weakness of spleen and stomach and indigestion and preparation method thereof |
| CN101884764A (en) * | 2009-05-15 | 2010-11-17 | 张春 | Medicament for treating chronic hepatitis splenomegaly or cirrhosis splenomegaly |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1457818A (en) * | 2002-05-16 | 2003-11-26 | 杨文志 | Poison expelling and astheniz resisting balance pill and its preparing method |
| CN101884764A (en) * | 2009-05-15 | 2010-11-17 | 张春 | Medicament for treating chronic hepatitis splenomegaly or cirrhosis splenomegaly |
| CN101708327A (en) * | 2009-10-27 | 2010-05-19 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating diseases of weakness of spleen and stomach and indigestion and preparation method thereof |
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Granted publication date: 20150415 Termination date: 20200428 |