CN103228318B - 使用者激活的自包含共封装的离子透入给药系统 - Google Patents

使用者激活的自包含共封装的离子透入给药系统 Download PDF

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Publication number
CN103228318B
CN103228318B CN201180055905.3A CN201180055905A CN103228318B CN 103228318 B CN103228318 B CN 103228318B CN 201180055905 A CN201180055905 A CN 201180055905A CN 103228318 B CN103228318 B CN 103228318B
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CN
China
Prior art keywords
electrode
conductive
conductive medium
delivery system
drug delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201180055905.3A
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English (en)
Chinese (zh)
Other versions
CN103228318A (zh
Inventor
T·B·塞布里
R·P·斯塔特普洛斯
M·A·维纳特鲁
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NuPathe Inc
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NuPathe Inc
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Publication date
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Publication of CN103228318A publication Critical patent/CN103228318A/zh
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Expired - Fee Related legal-status Critical Current
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
CN201180055905.3A 2010-11-23 2011-11-09 使用者激活的自包含共封装的离子透入给药系统 Expired - Fee Related CN103228318B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41662310P 2010-11-23 2010-11-23
US61/416,623 2010-11-23
PCT/US2011/059981 WO2012071175A1 (en) 2010-11-23 2011-11-09 User-activated self-contained co-packaged iontophoretic drug delivery system

Publications (2)

Publication Number Publication Date
CN103228318A CN103228318A (zh) 2013-07-31
CN103228318B true CN103228318B (zh) 2016-03-23

Family

ID=45044724

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201180055905.3A Expired - Fee Related CN103228318B (zh) 2010-11-23 2011-11-09 使用者激活的自包含共封装的离子透入给药系统

Country Status (12)

Country Link
US (1) US9327114B2 (enExample)
EP (1) EP2643048A1 (enExample)
JP (1) JP2013543773A (enExample)
CN (1) CN103228318B (enExample)
AU (1) AU2011332187B2 (enExample)
BR (1) BR112013012117A8 (enExample)
CA (1) CA2817824A1 (enExample)
EA (1) EA026254B1 (enExample)
IL (1) IL226067A0 (enExample)
MX (1) MX336812B (enExample)
NZ (1) NZ610305A (enExample)
WO (1) WO2012071175A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2817824A1 (en) 2010-11-23 2012-05-31 Nupathe, Inc. User-activated self-contained co-packaged iontophoretic drug delivery system
US9744353B2 (en) 2012-11-14 2017-08-29 Teva Pharmaceuticals International Gmbh Detection of presence and alignment of a therapeutic agent in an iontophoretic drug delivery device
TW201431570A (zh) 2012-11-22 2014-08-16 Ucb Pharma Gmbh 用於經皮投服羅替戈汀（Ｒｏｔｉｇｏｔｉｎｅ）之多天式貼片
CA2916183C (en) 2013-07-03 2022-03-29 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system with electronic component
EP2886153A1 (de) 2013-12-20 2015-06-24 LTS LOHMANN Therapie-Systeme AG System für die transdermale Abgabe von Wirkstoff
CA2948219C (en) 2014-05-20 2023-04-04 Lts Lohmann Therapie-Systeme Ag Method for adjusting the release of active agent in a transdermal delivery system
JP6573913B2 (ja) 2014-05-20 2019-09-11 エルテーエス ローマン テラピー−ジステーメ アーゲー ロチゴチンを含む経皮送達システム
US11752110B2 (en) 2014-05-20 2023-09-12 Lts Lohmann Therapie-Systeme Ag Transdermal delivery system including an interface mediator
JP2016002368A (ja) * 2014-06-18 2016-01-12 日本電信電話株式会社 経皮薬物送達システム
WO2018006069A1 (en) 2016-06-30 2018-01-04 Teva Pharmaceuticals International Gmbh Improved formulations for transdermal pharmaceutical systems
FR3152229A1 (fr) * 2023-08-25 2025-02-28 Feeligreen Dispositif de traitement de la peau

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US5817044A (en) * 1992-11-05 1998-10-06 Becton Dickenson And Company User activated iontophoertic device
WO2010078313A1 (en) * 2008-12-30 2010-07-08 Nupathe, Inc. Electronic control of drug delivery system

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US4917676A (en) 1986-11-20 1990-04-17 Ciba-Geigy Corporation User-activated transdermal therapeutic system
US4927408A (en) 1988-10-03 1990-05-22 Alza Corporation Electrotransport transdermal system
DE3903794A1 (de) 1989-02-09 1990-08-16 Lohmann Therapie Syst Lts Therapeutisches system zur transdermalen oder transmucosalen verabreichung von wirkstoffen und seine verwendung
US5047007A (en) 1989-12-22 1991-09-10 Medtronic, Inc. Method and apparatus for pulsed iontophoretic drug delivery
US5246418A (en) 1991-12-17 1993-09-21 Becton Dickinson And Company Iontophresis system having features for reducing skin irritation
US5499967A (en) 1992-02-27 1996-03-19 Societe Anonyme Dite: Laboratoires D'hygiene Societe Anonyme Dite: Et De Dietetique (L.H.D.) Transdermal drug delivery device with waveshape generator
FR2688106B1 (fr) 1992-02-27 1994-09-09 Lhd Lab Hygiene Dietetique Dispositif de generation d'une tension electrique de forme d'onde predeterminee, appareil ionophoretique d'administration transdermique de medicaments.
US5310404A (en) * 1992-06-01 1994-05-10 Alza Corporation Iontophoretic delivery device and method of hydrating same
US5445609A (en) 1993-05-28 1995-08-29 Alza Corporation Electrotransport agent delivery device having a disposable component and a removable liner
US5458569A (en) 1993-06-08 1995-10-17 Becton Dickinson And Company Wearable iontophoresis system
US5533971A (en) 1993-09-03 1996-07-09 Alza Corporation Reduction of skin irritation during electrotransport
JPH08155041A (ja) 1994-12-05 1996-06-18 Advance Co Ltd イオントフォレシス用新規高能率電極システム
US5697896A (en) 1994-12-08 1997-12-16 Alza Corporation Electrotransport delivery device
CN1170360A (zh) 1994-12-21 1998-01-14 瑟垃技术有限公司 具有粘性贴面和剥离密封圆片的经皮输送系统
US5879322A (en) 1995-03-24 1999-03-09 Alza Corporation Self-contained transdermal drug delivery device
IE960312A1 (en) 1995-06-02 1996-12-11 Alza Corp An electrotransport delivery device with voltage boosting¹circuit
ZA964320B (en) 1995-06-05 1997-01-13 Alza Corp Device for transdermal electrotransport delivery of fentanyl and sufentanil
US6881208B1 (en) 1995-06-05 2005-04-19 Joseph B. Phipps Method and device for transdermal electrotransport delivery of fentanyl and sufentanil
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US6167301A (en) 1995-08-29 2000-12-26 Flower; Ronald J. Iontophoretic drug delivery device having high-efficiency DC-to-DC energy conversion circuit
KR100281171B1 (ko) 1995-08-31 2001-03-02 나까도미 히로다카 이온토포레시스장치 및 그 전류제어방법
US5688232A (en) 1995-09-28 1997-11-18 Becton Dickinson And Company Iontophoretic drug delivery device having an improved controller
US5738647A (en) 1996-09-27 1998-04-14 Becton Dickinson And Company User activated iontophoretic device and method for activating same
US20010009983A1 (en) 1997-09-29 2001-07-26 Drug Delivery Technologies, Inc. Methods for implementing current delivery profiles used in an iontophoretic system
AU1997699A (en) 1997-12-16 1999-07-05 Alza Corporation Regulator with artificial load to maintain regulated delivery
JP4362012B2 (ja) 1997-12-17 2009-11-11 アルザ・コーポレーション 電流がプログラム調整されたイオン導入法
EP1170029B1 (en) 1999-04-12 2009-03-11 Hisamitsu Pharmaceutical Co., Inc. Device for iontophoresis
US6385488B1 (en) 1999-05-20 2002-05-07 Vyteris, Inc. Circuits for increasing the reliability of an iontophoretic system
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Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817044A (en) * 1992-11-05 1998-10-06 Becton Dickenson And Company User activated iontophoertic device
WO2010078313A1 (en) * 2008-12-30 2010-07-08 Nupathe, Inc. Electronic control of drug delivery system

Also Published As

Publication number Publication date
CA2817824A1 (en) 2012-05-31
AU2011332187B2 (en) 2016-03-03
BR112013012117A2 (pt) 2016-09-27
CN103228318A (zh) 2013-07-31
US9327114B2 (en) 2016-05-03
WO2012071175A1 (en) 2012-05-31
IL226067A0 (en) 2013-06-27
EA201390745A1 (ru) 2014-01-30
EA026254B1 (ru) 2017-03-31
EP2643048A1 (en) 2013-10-02
NZ610305A (en) 2015-10-30
MX336812B (es) 2016-02-02
US20130296766A1 (en) 2013-11-07
MX2013005430A (es) 2013-07-05
JP2013543773A (ja) 2013-12-09
BR112013012117A8 (pt) 2017-10-10
AU2011332187A1 (en) 2013-05-02

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Effective date of registration: 20160229

Address after: Perth, Switzerland - Jonathan

Applicant after: NUPATHE INC.

Address before: American Pennsylvania

Applicant before: NuPathe Inc.

CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20160323

Termination date: 20171109

CF01 Termination of patent right due to non-payment of annual fee