CN103213226B - A kind of preparation method who contains natural meat cinnamic aldehyde anti-inflammation lubricating type sheath - Google Patents
A kind of preparation method who contains natural meat cinnamic aldehyde anti-inflammation lubricating type sheath Download PDFInfo
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- CN103213226B CN103213226B CN201310160753.4A CN201310160753A CN103213226B CN 103213226 B CN103213226 B CN 103213226B CN 201310160753 A CN201310160753 A CN 201310160753A CN 103213226 B CN103213226 B CN 103213226B
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- sheath
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- cinnamic aldehyde
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Abstract
The present invention relates to a kind of preparation method who contains natural meat cinnamic aldehyde anti-inflammation lubricating type sheath, specifically can on natural emulsion sheath or NBR latex sheath finished product, directly apply cinnamic acid, also can conventional natural emulsion sheath or the raw material presulfurization operation of NBR latex sheath in, a certain amount of cinnamic acid is added equably and is distributed in natural emulsion or NBR latex together with other conventional batchings, moulding process floods into natural emulsion gloves sheath or the NBR latex sheath containing natural meat cinnamic aldehyde routinely again, then pass through crimping, chlorination, foam washing, rinsing, drying process obtains finished product, sheath prepared by the method can play the function of anti-inflammation and lubricated skin care, and cinnamic acid can also give out the smell of delicate fragrance simultaneously, eliminates the peculiar smell of human secretory, technique is simple, with low cost, and has saved resource, has improved production efficiency.
Description
Technical field
The present invention relates to the preparation method of sheath, particularly one contains natural meat cinnamic aldehyde anti-inflammation lubricant and keeps awayThe preparation method of pregnant cover, belongs to daily hygiene articles for use preparing technical field.
Background technology
Point out according to the up-to-date report of the World Health Organization, within 2011, the whole world has 2,500,000 people newly to infect AIDS virus, estimates at1700000 people's death, have reduced 700,000 than global new infection number before 10 years, have reduced 600,000 than the death toll of 2005. " ChinaThe report of AIDS preventing and controlling joint assessment " point out, by, China's accumulative total is reported patients infected hiv and AIDS in by the end of October, 2007Patient's 223501 examples, wherein AIDS patient's 62838 examples, dead report 22205 examples. Sheath is as the form with non-medicinePrevent pregnancy, in addition, sheath also has the effect of the spread of sexually transmitted diseases such as the gonorrhoea of preventing, AIDS (HIV), therefore also claims safetyCover. Present sheath raw material is normally with natural rubber or polyurethane, and they can only be used for contraception and shielding virus, can notEffectively play antibacterial and effect anti-inflammatory, the product of therefore developing quality high-quality be directly connected to the healthy of the public andSafety, is more and more subject to the attention of relevant government department.
Along with security needs, start in sheath, to add Chinese medicine as bactericide, as CN1348746A discloses onePlanting condom with Chinese medicine bactericide, is, after adding moisturizing agent and tackifier to mix Chinese medicine extract, to join inside and outside sheath, itsThe traditional Chinese medicinal components of Chinese medicine sterilizing liquid is: kuh-seng, frutus cnidii, Lappula echinata grass, the fruit of summer cypress, Radix Angelicae Sinensis, golden cypress, pericarpium zanthoxyli, betel nut, schizonepeta, wolfPoison etc. The present invention adopts cinnamic acid as anti-inflammation material, with low cost, better effects if.
Chinese cassia tree (CinnamomumcassiaPresl) is a kind of important Chinese herbal medicine, has the fire of benefit supporing yang, loose only coldBitterly, the function of warming meridian, is used for the treatment of impotence, frequent micturition, postpartum the retention of urine, cirrhotic ascites, asthma, Bronchopneumonia, aphtha,Baby diarrhea, children's hernia, rheumatism etc. In Chinese cassia tree, except containing some carbohydrate, also contain abundant cinnamon oil, it is mainWanting composition is cinnamic acid, and it is anticorrosion that cinnamic acid has sterilizing, particularly fungi had to significant curative effect, to Escherichia coli, withered grassBacillus and golden yellow staphylococcus, staphylococcus albus, Shigella shigae, Typhoid and paratyphoid first bacillus, pneumococcus, productGas bacillus, proteus, bacillus anthracis, Bacterium enteritidis, comma bacillus etc. have inhibitory action, and gram-positive bacteria is killedBacterium effect is remarkable, can be used for treating multiplely infecting the disease causing because of bacterium. Its MIC (MIC) is 0.02-0.07ul/ml, to deep pathomycete, MIC is 0.1-0.3ul/ml.
At present the research of Chinese cassia tree is mainly concentrated in medical science pharmacology, Japan medical science expert studies discovery, and cinnamic acid is to veryBacterium has significant curative effect, shows: cinnamic acid is anti-by 22 kinds of opportunistic fungus are carried out to STUDY ON ANTIFUNGAL EFFECT OF CINNAMYL ALDEHYDE researchThe active material of fungi, is mainly by destroying fungal cell wall, and medicine is infiltrated in fungal cell, destroys organelle and playsBactericidal action.
The present invention, first by cinnamic acid emulsification, improves its solubility, strengthens drug effect and bioavilability, has improved sulfuration effectRate; Join the effect that can play anti-inflammation in sheath; And China's Chinese cassia tree aboundresources output accounts for world's Chinese cassia tree productThe more than 80% of amount, and Guangdong, Guangxi two province's Chinese cassia tree output account for the more than 95% of China's Chinese cassia tree output, for the exploitation of resource and rationallyThe approach that provides is effectively provided.
Summary of the invention
The object of this invention is to provide a kind of preparation method who contains natural meat cinnamic aldehyde sheath, the sheath of preparation can riseTo the function of anti-inflammation and lubricated skin care.
In order to address the above problem, the technical solution adopted in the present invention is:
A preparation method who contains natural meat cinnamic aldehyde anti-inflammation lubricating type sheath, comprising:
(1) on natural emulsion sheath or NBR latex sheath finished product, directly apply the cinnamic acid through Over emulsfication;
(2) add the meat through Over emulsfication producing in the raw material that natural emulsion sheath or NBR latex sheath useCinnamic aldehyde.
The cinnamic acid that adds in raw material described in said method (2) refers at conventional natural emulsion sheath or NBRIn the raw material presulfurization operation of breast sheath, a certain amount of cinnamic acid is added equably and divided together with other conventional batchingsFall apart in natural emulsion or NBR latex, then moulding process floods into the natural emulsion gloves contraception containing natural meat cinnamic aldehyde routinelyCover or NBR latex sheath, then obtain finished product by crimping, chlorination, foam washing, rinsing, drying process.
Wherein said cinnamic acid and the mass ratio of rubber are preferably 0.5 ~ 1.5:100; Preferred mass ratio is 0.8:100 or 1.2:100.
In order better to implement the present invention, described cinnamic acid need first be prepared into emulsified meat cinnamic aldehyde, and concrete grammar is:In the three-necked bottle of 250mL, add 0.5g polyvinyl alcohol (PVA-1788) and 0.1g sodium alginate, 100mL distilled water, stirsMix lower heating for dissolving 2 hours, be chilled to room temperature, add 3g polyethylene glycol-200 to be dissolved in the 10ml aqueous solution, 10 points of constant temperature stirring and emulsifyingZhong Hou, drips the mixture of 1.28g IPDI (IPDI), 10.0g cinnamic acid and 3g acetone under ice bath,Control mixing speed in about 1500rpm, drip and continue to stir 30 minutes, ultrasonic refinement after finishing 15 minutes under ice bath, obtain lightYellow emulsion product, obtains emulsified meat cinnamic aldehyde, can arbitrary proportion miscible.
In a preferred embodiment, the deal of the mixture of described rubber and cinnamic acid and vulcanizing agent, activating agentCount with mass parts:
100 parts, the mixture of rubber and cinnamic acid
3 ~ 7 parts of vulcanizing agents
5 ~ 10 parts of activating agents.
Wherein, can further preferably make part of the mixture of described rubber and cinnamic acid and vulcanizing agent, activating agentAmount is counted with mass parts:
100 parts, the mixture of rubber and cinnamic acid
5 parts of vulcanizing agents
8 parts of activating agents.
In another preferred embodiment, when mixing, be 50 ~ 80 DEG C of ultrasonic agitation processing in temperature, the time is 20 ~50 minutes. In another preferred embodiment, when sulfuration, temperature is 40 ~ 70 DEG C, and the time is 1 ~ 2 hour
The invention has the beneficial effects as follows:
(1) the present invention by adding in the raw material presulfurization operation of conventional natural emulsion sheath or NBR latex sheathAdd emulsified meat cinnamic aldehyde, cinnamic acid is distributed in the sheath after moulding equably, when wearing, the cinnamic acid in sheath can be notSeparate disconnectedly and act on skin, play the function of anti-inflammation and lubricated skin care, cinnamic acid can also give out delicate fragrance simultaneouslySmell, eliminate the peculiar smell of human secretory.
(2) technique of the present invention is simple, easy to operate, raw material with low cost, and improved rate of cure, reduce raw material and useAmount, the performance of product meets the requirement of national standard.
Detailed description of the invention:
Below by embodiment, the present invention is described in further details, these embodiment are only used for illustrating the present invention, andDo not limit the scope of the invention.
Cinnamic acid is prepared into emulsified meat cinnamic aldehyde, and concrete grammar is: in the three-necked bottle of 250mL, add 0.5g polyvinyl alcohol(PVA-1788) and 0.1g sodium alginate, 100mL distilled water, stirs lower heating for dissolving 2 hours, is chilled to room temperature, adds 3gPolyethylene glycol-200 are dissolved in the 10ml aqueous solution, and constant temperature stirring and emulsifying, after 10 minutes, drips 1.28g isophorone two different under ice bathThe mixture of cyanate (IPDI), 10.0g cinnamic acid and 3g acetone, controls mixing speed in 1500rpm left and right, drips Bi HoujiContinue and under ice bath, stir 30 minutes, ultrasonic refinement 15 minutes, obtain faint yellow emulsion product, obtain emulsified meat cinnamic aldehyde, canArbitrary proportion is miscible.
Embodiment 1
(1) 100 parts of standby rubber, 0.8 part of cinnamic acid, 5 parts of vulcanizing agents, 7 parts of activating agents;
(2) rubber is mixed with cinnamic acid, then add vulcanizing agent and activating agent;
(3) be 50 DEG C of ultrasonic agitation processing in temperature, the time is 50 minutes;
(4) after, be 40 DEG C of sulfurations 2.0 hours in temperature;
(5) then can obtain finished product by crimping, chlorination, foam washing, rinsing, drying process.
Embodiment 2
(1) 100 parts of standby rubber, 1.2 parts of cinnamic acids, 6 parts of vulcanizing agents, 5 parts of activating agents;
(2) rubber is mixed with cinnamic acid, then add vulcanizing agent and activating agent;
(3) be 60 DEG C of ultrasonic agitation processing in temperature, the time is 35 minutes;
(4) after, be 50 DEG C of sulfurations 1.5 hours in temperature;
(5) then can obtain finished product by crimping, chlorination, foam washing, rinsing, drying process.
Embodiment 3
(1) 100 parts of standby rubber, 0.5 part of cinnamic acid, 3 parts of vulcanizing agents, 8 parts of activating agents;
(2) rubber is mixed with cinnamic acid, then add vulcanizing agent and activating agent;
(3) be 70 DEG C of ultrasonic agitation processing in temperature, the time is 25 minutes;
(4) after, be 60 DEG C of sulfurations 1.0 hours in temperature;
(5) then can obtain finished product by crimping, chlorination, foam washing, rinsing, drying process.
Embodiment 4
(1) 100 parts of standby rubber, 1.5 parts of cinnamic acids, 7 parts of vulcanizing agents, 10 parts of activating agents;
(2) rubber is mixed with cinnamic acid, then add vulcanizing agent and activating agent;
(3) be 80 DEG C of ultrasonic agitation processing in temperature, the time is 20 minutes;
(4) after, be 70 DEG C of sulfurations 0.8 hour in temperature;
(5) then can obtain finished product by crimping, chlorination, foam washing, rinsing, drying process.
Embodiment 5
A certain amount of emulsified meat cinnamic aldehyde is directly coated on sheath.
Claims (6)
1. a preparation method who contains natural meat cinnamic aldehyde anti-inflammation lubricating type sheath, is characterized in that:
(1) this sheath directly applies the cinnamic acid through Over emulsfication on natural emulsion sheath or NBR latex sheath finished productOr add the cinnamic acid through Over emulsfication producing in the raw material that natural emulsion sheath or NBR latex sheath use, described inCinnamic acid and the mass ratio of rubber be 0.5 ~ 1.5:100;
The preparation method of emulsified meat cinnamic aldehyde is: in the three-necked bottle of 250mL, add 0.5g PVAC polyvinylalcohol-1788 and 0.1gSodium alginate, 100mL distilled water, stirs lower heating for dissolving 2 hours, is chilled to room temperature, adds 3g polyethylene glycol-200 to be dissolved inThe 10ml aqueous solution, constant temperature stirring and emulsifying, after 10 minutes, drips 1.28g IPDI IPDI, 10.0g under ice bathThe mixture of cinnamic acid and 3g acetone, controls mixing speed in 1500rpm left and right, drips complete rear continuation and under ice bath, stirs 30 minutesAnd ultrasonic refinement 15 minutes, obtains faint yellow emulsion product, obtains emulsified meat cinnamic aldehyde.
2. a kind of preparation method who contains natural meat cinnamic aldehyde anti-inflammation lubricating type sheath according to claim 1, itsBe characterised in that: its preparation method is to be directly coated with and to be covered with on the natural emulsion sheath preparing or NBR latex sheath finished productCinnamic acid or in the raw material presulfurization operation of natural emulsion sheath or NBR latex sheath, connects a certain amount of cinnamic acidAdd equably together and be distributed in natural emulsion or NBR latex with other conventional batching, then moulding process floods routinelyBecome natural emulsion sheath or NBR latex sheath containing natural meat cinnamic aldehyde, then by crimping, chlorination, foam washing, rinsing, dryDrying process obtains finished product.
3. a kind of preparation method who contains natural meat cinnamic aldehyde anti-inflammation lubricating type sheath according to claim 1, itsBe characterised in that: described cinnamic acid and the mass ratio of rubber are 0.8:100 or 1.2:100.
4. a kind of preparation method who contains natural meat cinnamic aldehyde anti-inflammation lubricating type sheath according to claim 2, itsBe characterised in that: the deal of described rubber and the mixture of cinnamic acid and vulcanizing agent, activating agent is counted with mass parts:
100 parts, the mixture of rubber and cinnamic acid
3 ~ 7 parts of vulcanizing agents
5 ~ 10 parts of activating agents.
5. a kind of preparation method who contains natural meat cinnamic aldehyde anti-inflammation lubricating type sheath according to claim 2, itsBe characterised in that: the deal of described rubber and the mixture of cinnamic acid and vulcanizing agent, activating agent is counted with mass parts:
100 parts, the mixture of rubber and cinnamic acid
5 parts of vulcanizing agents
8 parts of activating agents.
6. according to a kind of preparation side of containing natural meat cinnamic aldehyde anti-inflammation lubricating type sheath described in claim 4 or 5Method, is characterized in that: when sulfuration, temperature is 40 ~ 70 DEG C, and the time is 1 ~ 2 hour.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310160753.4A CN103213226B (en) | 2013-05-06 | 2013-05-06 | A kind of preparation method who contains natural meat cinnamic aldehyde anti-inflammation lubricating type sheath |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310160753.4A CN103213226B (en) | 2013-05-06 | 2013-05-06 | A kind of preparation method who contains natural meat cinnamic aldehyde anti-inflammation lubricating type sheath |
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| CN103213226A CN103213226A (en) | 2013-07-24 |
| CN103213226B true CN103213226B (en) | 2016-05-25 |
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| CN201310160753.4A Expired - Fee Related CN103213226B (en) | 2013-05-06 | 2013-05-06 | A kind of preparation method who contains natural meat cinnamic aldehyde anti-inflammation lubricating type sheath |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103445903B (en) * | 2013-09-25 | 2015-05-13 | 桂林恒保健康用品有限公司 | Condom capable of treating chronic pelvic inflammation |
| CN103445905B (en) * | 2013-09-25 | 2015-06-17 | 桂林恒保健康用品有限公司 | Condom capable of treating gynecological inflammations |
| US20170172786A1 (en) * | 2015-12-21 | 2017-06-22 | Ansell Limited | Coated condom |
| CN112812385A (en) * | 2021-01-15 | 2021-05-18 | 威乐士医疗卫生用品（湖北）有限公司 | Preparation method of latex condom |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1191130A (en) * | 1997-02-18 | 1998-08-26 | 雷学军 | Anti-AIDS virus, anti-Treponema pallidum, anti-gonococcus, anti-candida albicans and anti-trichomonas natural drug |
| CN1348746A (en) * | 2000-10-13 | 2002-05-15 | 郭晓勤 | Condom with Chinese medicine bactericide |
| CN101596131A (en) * | 2009-06-18 | 2009-12-09 | 周政明 | A kind of condom containing antibacterial and antiviral medicine and preparation method thereof |
| CN101974174A (en) * | 2010-10-22 | 2011-02-16 | 中国热带农业科学院农产品加工研究所 | Method for preparing sterilization and inflammation reducing condom containing natural aloe extract |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07289575A (en) * | 1994-04-27 | 1995-11-07 | Okamoto Ind Inc | Rerfume-added condom and method for adding perfume to condom |
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2013
- 2013-05-06 CN CN201310160753.4A patent/CN103213226B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1191130A (en) * | 1997-02-18 | 1998-08-26 | 雷学军 | Anti-AIDS virus, anti-Treponema pallidum, anti-gonococcus, anti-candida albicans and anti-trichomonas natural drug |
| CN1348746A (en) * | 2000-10-13 | 2002-05-15 | 郭晓勤 | Condom with Chinese medicine bactericide |
| CN101596131A (en) * | 2009-06-18 | 2009-12-09 | 周政明 | A kind of condom containing antibacterial and antiviral medicine and preparation method thereof |
| CN101974174A (en) * | 2010-10-22 | 2011-02-16 | 中国热带农业科学院农产品加工研究所 | Method for preparing sterilization and inflammation reducing condom containing natural aloe extract |
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| CN103213226A (en) | 2013-07-24 |
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