CN1191130A - Anti-AIDS virus, anti-Treponema pallidum, anti-gonococcus, anti-candida albicans and anti-trichomonas natural drug - Google Patents

Anti-AIDS virus, anti-Treponema pallidum, anti-gonococcus, anti-candida albicans and anti-trichomonas natural drug Download PDF

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CN1191130A
CN1191130A CN97107961A CN97107961A CN1191130A CN 1191130 A CN1191130 A CN 1191130A CN 97107961 A CN97107961 A CN 97107961A CN 97107961 A CN97107961 A CN 97107961A CN 1191130 A CN1191130 A CN 1191130A
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oil
candida albicans
treponema pallidum
infusorian
hiv
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雷学军
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Abstract

A natural medicine for deactivating AIDS virus (HIV) and killing Treponema pallidum, gonococcus, candida albicans, and trichomonad by adding it to contraceptive film, condom, scented soap, bath lotion and washing powder contains one or more active components extracted from natural plants.

Description

The natural drug of AIDS virus resisting, treponema pallidum, gonococcus, Candida albicans, infusorian
The present invention relates to the natural drug of AIDS virus resisting (HIV), treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian.
On June 5th, 1981, authoritative health organ of the U.S.---Center for Disease Control (CDC) has reported 5 peculiar and fearful cases that recur in very short time: the commasculatio person of 5 youths, all suffered from a kind of very rare pneumonia---Pneumocystis pneumonia, and this several should be that strong people does not know that what reason lost minimum immunocompetence, therefore and dead report is when sending, and wherein 2 people.July 3 afterwards, this mechanism reports that again 26 male adults homosexual persons suffer from a kind of malignant tumor, and these 26 patients have also lost immunologic function, existing 8 people's death when report sends.So concentrate these patients that occur in the short time, finally all devitalized.People recognize among shock, the human challenge that faces a kind of new incurable disease again.Here it is after 5 years " acquired immune deficiency syndrome (AIDS) " named (AIDS).
After 1981, HIV the infected every year in the world, some area even several times, tens times ground increased at double.Be increased to 2,180 ten thousand people 1996 from about 100,000 people at the beginning of the eighties soon.The countries and regions of involving also expand to more than 200 by one or two.People have calculated, and the whole world all will increase by 8500 new the infecteds every day.World Health Organization (WHO) estimates that global HIV the infected will reach 4,000 ten thousand-100,000,000 people in 2000.The AIDS oncoming force is burbulent violent, and the case fatality rate height is referred to as " century plague " " super cancer " by people.Countries in the world society, economy have been caused serious harm.The infection of treponema pallidum, gonococcus, Candida albicans, infusorian makes the patient skin mucosa be easy to breakage, provides more infection chance to HIV.
The object of the present invention is to provide the natural drug of the anti-HIV of a class, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian.
Anti-HIV provided by the invention, treponema pallidum, gonorrhea diplococcus, Candida albicans, the natural drug of infusorian comprises in the following combination one or more: paeonol 0.1-2%, Camphora 0.01-3%, Oleum Caryophylli 0.05-2%, gossypol 0.1-3%, cinnamic aldehyde 0.3-1%, fennel oil 0.05-2.2%, catechol 0.1-2%, eucalyptol 0.02-2.5%, benzoic acid 0.6-3%, glycyrrhizin 0.1-1.5%, Moschus 0.01-2.5%, oleanolic acid 0.01-3%, oil of pepper 0.01-2.1%, piperine 0.1-2%, Fortunella crassifolia Swingle quintessence oil 0.01-2%, garlicin 0.01-2%, oil of ginger 0.001-2.5%, Bufo siccus 0.01-2%, Oleum menthae 0.01-1.5%, Borneolum Syntheticum 0.01-5%, nitidine 0.01-3.5%, arecoline 0.01-3%, Oleum Anisi Stellati 0.01-2%, ginnol 0.05-3%, orange peel oil 0.01-3.5%, theobromine 0.01-2%, theophylline 0.1-3%, berberine 0.1-1.2%, hop oil 0.1-5%, anethole 0.01-3.8%, laurel fat 0.01-2%, solanine 0.1-2%, tomatidine 0.01-3%, farrerol 0.1-3%, Oleum Citri grandis 0.1-3%, Zibethum 0.01-2%, oil of rosemary 0.02-4%, perilla oil 0.1-3%, Citrus aurantium L. var. amara Engl. Oil 0.2-2%, Oleum Rosae Rugosae 0.01-2.5%, cardamom oil 0.01-2.8%, thymol 0.1-3%, magnolol 0.1-3%, onion essential oil 0.1-3%, baicalin 0.5-3%, chrysophanol 0.1-3%, emodin 0.01-2%, ginsenoside 0.1-2%, jateorhizine 0.01-1%, kaempferol 0.1-3%, naringin 0.1-1%, chrysophanic acid 0.01-2%, thymol 0.01-1%, deoxycholic acid 0.01-1%, Herba Andrographis 0.03-1.5%, houttuynine sodium bisulfite 0.1-3%, Isatan 0.1-3%, sinigrin 0.1-2%, chlorogenic acid 0.01-1%, shikonin 0.1-0.5%, cuspidatumin 0.1-1%.
Solid drugs in the above-mentioned component is before being prepared into various medicines and health care product, adopt colloid mill to wear into the superfine powder of 200 mesh sieves earlier, to increase the specific surface of medicine, make medicine in digestive tract, be easy to absorb and increase health care product Chinese medicine dissolution rate, improve the sterilization of medicine and the ability of deactivation HIV, thereby reduced amount of drug.
The general employing of pharmaceutical compositions used in the present invention is composite, reaches Mucocutaneous zest to reduce adverse drug abnormal smells from the patient and uncomfortable mouthfeel.And stop and disturb the bio-metabolic process of HIV, treponema pallidum, gonorrhea diplococcus, infusorian from many aspects: the HIV that duplicates, stops that suppresses virus enters the biosynthesis etc. of the DNA of T4 lymphocyte and treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian, thereby reaches deactivation HIV rapidly, kills treponema pallidum, the effect of gonorrhea diplococcus, Candida albicans, infusorian.
Various medicine of the present invention according to the characteristics of their physicochemical properties, can be divided into volatile oil, alkaloids, phenols, acids, animal class five classes.Preparation method is as follows:
1, volatile oil medicine: cinnamic aldehyde, eucalyptol, Camphora, orange peel oil, anisic aldehyde, Oleum Caryophylli, Oleum Anisi Stellati, Oleum Ocimi Gratissimi, fennel oil, cardamom oil, Oleum Rosae Rugosae, Citrus aurantium L. var. amara Engl. Oil, perilla oil, oil of rosemary, Oleum Citri grandis, seed oil of Herba Apii graveolentis, Mentholum, oil of pepper, anethole, Borneolum Syntheticum, laurel fat, Fortunella crassifolia Swingle quintessence oil, onion essential oil, naringin, garlicin, oil of ginger, hop oil.Its preparation method is as follows: raw medicinal herbs → chopping →
Figure A9710796100061
2, alkaloids medicament: nitidine, jateorhizine, solanine, theobromine, arecoline, theophylline, tomatidine, berberine, fagarine, piperine.Its preparation method is as follows:
Figure A9710796100062
Figure A9710796100063
3, phenols medicine: thymol, catechol, kaempferol, thymol, gossypol, chrysophanol, paeonol, magnolol.Its preparation method is as follows: raw medicinal herbs → chopping---
Figure A9710796100064
4, acids medicine: benzoic acid, chrysophanic acid, cinnamic acid, oleanolic acid, deoxycholic acid, chlorogenic acid.Its preparation method is as follows:
Figure A9710796100071
5, animal kind medicine thing: Zibethum, Moschus, Bufo siccus.Its preparation method is as follows: directly take off medicinal organ on one's body from medicinal animal, dry in the shade, be used as medicine.
Experiment shows that medicine of the present invention has deactivation completely and killing action to HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian.The infection of HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian mainly contains following approach:
1, with the people sexual intercourse of having infected HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian;
2, use by HIV, the polluted syringe needle of treponema pallidum or needle tubing shoot up, medicine, vaccine;
3, input is by HIV, the polluted blood plasma of treponema pallidum and blood products;
4, the women of infected by HIV, treponema pallidum gestation fertility;
5, HIV, syphilis spiral enter in another human body with the skin or the mucosa of the infected's body fluid (blood, seminal fluid, vaginal secretion, tear, saliva, urine, milk) by the breakage of direct contact.
Approach in view of above HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian propagation, one or more make medicine anti-AIDS for oral administration, sexually transmitted disease (STD) and one or more are added in condom, contraceptive membrane, fragrant soap, bath gel, the detergent with said medicine the medicine of the anti-HIV of the present invention, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian, can yet be regarded as a kind of not only convenient but also the multipath method of preventing infected by microbes such as HIV and treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian and propagation for a long time.
Embodiment 1:
The contraceptive membrane of anti-HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian
One, experimental technique: will contain the contraceptive membrane 15mg that 2mg nonyl phenyl polyglycol ether, 1mg paeonol, 2mg glycyrrhizin, 1.5mg polyvinyl alcohol, 1mg glycerol, distilled water etc. are made, be dissolved in the 5ml normal saline, taking liquid 1ml directly injects the Embryo Gallus domesticus that has infected HIV; Taking liquid 1ml directly injects the culture medium of syphilize spirillum, gonorrhea diplococcus, Candida albicans, infusorian respectively.The test medicinal liquid is to the deactivation of HIV and to the killing action of treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian.The normal saline that matched group is taked not contain medicine is made parallel control.
Two, experimental result:
1, HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian survive good in the matched group.
2, HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian complete inactivation or be killed in 2-2.5 minute respectively in the experimental group.Embodiment 2:
The fancy soap of anti-HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian
One, experimental technique: 0.2g paeonol, 0.3g glycyrrhizin, 0.1g cinnamic aldehyde, soap base is an amount of, essence is an amount of, makes fancy soap 100g.Getting 50mg is dissolved in the 5ml normal saline.Handle with embodiment 1 same procedure.
Two, experimental result:
1, HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian survive good in the matched group.
2, HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian complete inactivation or be killed in 1.5-2 minute respectively in the experimental group.Embodiment 3:
The condom of anti-HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian
One, experimental technique:, be bonded on the interior adventitia of condom with 2mg gossypol, 2mg paeonol, 2mg benzoic acid and 10mg Pulvis Talci mixing.With adventitia in the 5ml normal saline flushing, collect medicinal liquid (guaranteeing that amount of liquid medicine is 5ml).Handle with embodiment 1 same procedure.
Two, experimental result:
1, HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian survive good in the matched group.
2, HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian complete inactivation or be killed in 1-1.5 minute respectively in the experimental group.Embodiment 4:
The bath gel of anti-HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian
One, experimental technique:, get finished product 10mg and be dissolved in the 5ml normal saline with 0.1% cinnamic aldehyde, 0.2% ginnol, 0.1% Oleum Caryophylli and bath gel substrate 99.6g mixing.Handle with embodiment 1 same procedure.
Two, experimental result:
1, HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian survive good in the matched group.
2, in the experimental group HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian respectively at 1-1.5 minute with interior complete inactivation or be killed.Embodiment 5:
The detergent of anti-HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian
One, experimental technique: get 1g Mentholum, 0.5g anethole, 98.5g detergent substrate and make the 100g detergent altogether.Get 5mg and be dissolved in the 5ml normal saline, handle with embodiment 1 same procedure.
Two, experimental result:
1, HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian survive good in the matched group.
2, in the experimental group HIV, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian respectively at 2-2.5 minute with interior complete inactivation or be killed.

Claims (6)

1, the natural drug of AIDS virus resisting (HIV), treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian is characterized in that containing in this medicine a kind of in the following composition:
Paeonol 0.1-2%, Camphora 0.01-3%, Oleum Caryophylli 0.05-2%, gossypol 0.1-3%, cinnamic aldehyde 0.3-1%, fennel oil 0.05-2.2%, catechol 0.1-2%, eucalyptol 0.02-2.5%, benzoic acid 0.6-3%, glycyrrhizin 0.1-1.5%, Moschus 0.01-2.5%, oleanolic acid 0.01-3%, oil of pepper 0.01-2.1%, piperine 0.1-2%, Fortunella crassifolia Swingle quintessence oil 0.01-2%, garlicin 0.01-2%, oil of ginger 0.001-2.5%, Bufo siccus 0.01-2%, Oleum menthae 0.01-1.5%, Borneolum Syntheticum 0.01-5%, nitidine 0.01-3.5%, arecoline 0.01-3%, Oleum Anisi Stellati 0.01-2%, ginnol 0.05-3%, orange peel oil 0.01-3.5%, theobromine 0.01-2%, theophylline 0.1-3%, berberine 0.1-1.2%, hop oil 0.1-5%, anethole 0.01-3.8%, laurel fat 0.01-2%, solanine 0.1-2%, tomatidine 0.01-3%, farrerol 0.1-3%, Oleum Citri grandis 0.1-3%, Zibethum 0.01-2%, oil of rosemary 0.02-4%, perilla oil 0.1-3%, Citrus aurantium L. var. amara Engl. Oil 0.2-2%, Oleum Rosae Rugosae 0.01-2.5%, cardamom oil 0.01-2.8%, thymol 0.1-3%, magnolol 0.1-3%, onion essential oil 0.1-3%, baicalin 0.5-3%, chrysophanol 0.1-3%, emodin 0.01-2%, ginsenoside 0.1-2%, jateorhizine 0.01-1%, kaempferol 0.1-3%, naringin 0.1-1%, chrysophanic acid 0.01-2%, thymol 0.01-1%, deoxycholic acid 0.01-1%, Herba Andrographis 0.03-1.5%, houttuynine sodium bisulfite 0.1-3%, Isatan 0.1-3%, sinigrin 0.1-2%, chlorogenic acid 0.01-1%, shikonin 0.1-0.5%, cuspidatumin 0.1-1%, surplus is an adjuvant.
2, the natural drug of anti-HIV according to claim 1, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian is characterized in that containing in this medicine:
0.5% paeonol, 0.1% fennel oil, 1.5% benzoic acid, 0.1% oleanolic acid, 0.2% piperine, 0.25% nitidine, 0.1% arecoline, 0.1% theophylline, 0.3% anethole, 0.5% Oleum Citri grandis, 1% Citrus aurantium L. var. amara Engl. Oil, 1.5% baicalin, 0.1% emodin, 0.1% kaempferol, 0.1% deoxycholic acid, 2.5% houttuynine sodium bisulfite, surplus are adjuvant.
3, the natural drug of anti-HIV according to claim 1, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian is characterized in that containing in this medicine:
0.1% Oleum Caryophylli, 2% Moschus, 0.05% garlicin, 2% ginnol, 3% orange peel oil, 0.05% laurel fat, 1.5% Zibethum, 1% Oleum Rosae Rugosae, 2.2% cardamom oil, 2% chrysophanol, 0.5% naringin, 1% chrysophanic acid, 0.4% Isatan, 0.1% sinigrin, 0.2% shikonin, surplus are adjuvant.
4, the natural drug of anti-HIV according to claim 1, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian is characterized in that containing in this medicine:
0.1% Camphora, 0.1% catechol, 2.5% gossypol, 1% glycyrrhizin, 0.05% Fortunella crassifolia Swingle quintessence oil, 1.5% Bufo siccus, 1% Oleum menthae, 1.5% tomatidine, 2.5% farrerol, 0.5% perilla oil, 1% ginsenoside, 0.5% thymol, 0.5% cuspidatumin, 1% chlorogenic acid, 1% Herba Andrographis, surplus are adjuvant.
5, the natural drug of anti-HIV according to claim 1, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian is characterized in that containing in this medicine:
0.5% cinnamic aldehyde, 2% eucalyptol, 1% oil of pepper, 1.5% oil of ginger, 4% Borneolum Syntheticum, 1% Oleum Anisi Stellati, 2% theobromine, 1% berberine, 2% hop oil, 1% solanine, 3% oil of rosemary, 1.5% thymol, 0.2% magnolol, 1% Bulbus Allii Cepae, 0.5% jateorhizine, surplus are adjuvant.
6, be prepared into any preparation according to the natural drug of the described any anti-HIV of claim 1 to 5, treponema pallidum, gonorrhea diplococcus, Candida albicans, infusorian and join in contraceptive membrane, fancy soap, condom, bath gel, the detergent as additive.
CN97107961A 1997-02-18 1997-02-18 Anti-AIDS virus, anti-Treponema pallidum, anti-gonococcus, anti-candida albicans and anti-trichomonas natural drug Pending CN1191130A (en)

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* Cited by examiner, † Cited by third party
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CN101757119A (en) * 2010-03-03 2010-06-30 湖南天龙制药有限公司 Medicine composition for treating vaginitis as well as gel and preparation method thereof
CN101433671B (en) * 2008-11-27 2011-05-04 崔凤玉 Medicine for treating syphilis
CN103213226A (en) * 2013-05-06 2013-07-24 中国热带农业科学院南亚热带作物研究所 Preparation method of antisepsis and anti-inflammation lubrication-type condom containing natural cinnamyl aldehyde
CN104621196A (en) * 2015-03-15 2015-05-20 孔涛 Prepared composition for killing white ants in printing and dyeing room
CN104663748A (en) * 2015-03-15 2015-06-03 孔涛 Method for preparing preparation for killing termite in printing and dyeing room
ITUB20150876A1 (en) * 2015-05-21 2016-11-21 Akademy Pharma S R L NUTRACEUTICAL COMPOUND FOR THE TREATMENT OF EXCESS URIC ACID

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101433671B (en) * 2008-11-27 2011-05-04 崔凤玉 Medicine for treating syphilis
CN101757119A (en) * 2010-03-03 2010-06-30 湖南天龙制药有限公司 Medicine composition for treating vaginitis as well as gel and preparation method thereof
CN103213226A (en) * 2013-05-06 2013-07-24 中国热带农业科学院南亚热带作物研究所 Preparation method of antisepsis and anti-inflammation lubrication-type condom containing natural cinnamyl aldehyde
CN103213226B (en) * 2013-05-06 2016-05-25 中国热带农业科学院南亚热带作物研究所 A kind of preparation method who contains natural meat cinnamic aldehyde anti-inflammation lubricating type sheath
CN104621196A (en) * 2015-03-15 2015-05-20 孔涛 Prepared composition for killing white ants in printing and dyeing room
CN104663748A (en) * 2015-03-15 2015-06-03 孔涛 Method for preparing preparation for killing termite in printing and dyeing room
CN104621196B (en) * 2015-03-15 2015-12-02 江阴市红柳被单厂有限公司 A kind of formulation for room cure of termite of printing and dyeing
ITUB20150876A1 (en) * 2015-05-21 2016-11-21 Akademy Pharma S R L NUTRACEUTICAL COMPOUND FOR THE TREATMENT OF EXCESS URIC ACID

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