CN101780179B - Multifunctional plant composition and application thereof as well as multifunctional plant extractive composition, application and antibiotic composition thereof - Google Patents
Multifunctional plant composition and application thereof as well as multifunctional plant extractive composition, application and antibiotic composition thereof Download PDFInfo
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Abstract
The invention discloses a multifunctional plant composition which is characterized by comprising senecio plants, verbenaceae plants, solanum plants and serissa plants. Aiming at the limit of chemically synthesized antibiotic products, the invention provides a skin and mucosa antibiotic composition prepared from natural active matters, and the composition can effectively prevent and cure pathological changes of the skin and the mucosa of the human body, which is caused by bacteria or fungi. The invention has the advantages of environmental protection, no irritation, long-time and large-area use, strong antibiotic and antipruritic capacity, quick response, simple preparation process, low cost, and the like.
Description
Technical field
The present invention relates to a kind of multifunctional plant composition, its purposes, multifunctional plant extractive composition, its purposes and bactericidal composition.
Background technology
The mucosa that is positioned at skin surface and body surface is the first line of defence that human body is resisted extraneous various stimulation (machinery, physics, chemistry and biostimulation), so skin surface is sick, mucosa infection is very common, multiple.Wherein biological, infective skin, mucosal disease are common especially.External chemosynthesis antimicrobial product is skin, the mucosa infection that is commonly used to treatment or prevention infection.Since nearly half a century, the development of chemosynthesis antimicrobial product is very rapid.But then, corresponding chemosynthesis antimicrobial product have various side effect as: 1) cause skin, mucous membrane irritability; 2) cause skin, mucosa Resistant strain; 3) long-term and large area is used, and can cause chemosynthesis product to produce toxicity at people's cylinder accumulation; 4) in use procedure, may cause skin strong and stimulating, for example burn feeling, sensation of pricking.
Therefore exploitation have no side effect, non-stimulated, can be for a long time, the non-chemically synthetic antimicrobial product of large area use, be the subject matter that this area is faced.Current also some plant extract is used for the treatment of the product of skin, mucosa infection, but its curative effect is slow, or has certain zest, or the plants herb kind of selecting is too much, and complex manufacturing technology is difficult for implementing.
Summary of the invention
The object of the invention is in order to overcome deficiency of the prior art, provide a kind of can anti-Staphylococcus aureus, the multifunctional plant composition of Candida albicans.
For realizing above object, the present invention is achieved through the following technical solutions:
Multifunctional plant composition, is characterized in that, comprises Senecio plant, Verbenaceae, nightshade and serissa plants.
Preferably, according to weight percentage, comprise Senecio plant 5%～50%, Verbenaceae 20%～70%, nightshade 5%～50% and serissa plants 20%～70%.
Another object of the present invention is to provide multifunctional plant composition for the preparation of the purposes in antibacterial.
Described antibacterial, be both included in human body or other animal bodies positions and used the generation with prevention, inhibition pathogenic bacteria before by pathogenic infection; Be also included within the rehabilitation that human body or the infected position of other animal bodies are killed pathogenic bacterium, promoted body.
Described antibacterial, both can be used as separately antibacterial by multifunctional plant composition, also can with use other article at human body to mix to be jointly used as antibacterial.While using separately, both can directly use the present composition; Also can be attached on available carrier and be used, as be made medicinal cotton sliver etc.While mixing common use with other article, can jointly make cosmetics use, make drug use with pharmaceutic adjuvant with preparing cosmetic composition adjuvant, also can with adjuvant, make hygienic article with daily hygiene care institution and use.
The preferably application in one or both the antibacterial of multifunctional plant composition in preparing anti-Staphylococcus aureus and Candida albicans.
Another object of the present invention is to provide a kind of multifunctional plant extractive composition, it is characterized in that, comprises Senecio plant extract, Verbenaceae extract, nightshade extract and serissa plants extract.
In the present invention, above-mentioned plant is carried out, after extraction process, using its extract, have better effect.
Preferably, the compositions of described extract is to extract and obtain from comprising according to weight percentage from the raw material of Senecio plant 5%～50%, Verbenaceae 20%～70%, nightshade 5%～50% and serissa plants 20%～70% proportioning.
Preferably, described extract is for being used aqueous solvent to extract.More preferably, for the plant material that extracts and the weight ratio of water, it is 5: 1～1: 50.
The extractive composition of above-mentioned plant, both can every kind of plant extract separately rear mixed extract; Also after each plant can being mixed, in water, jointly extract.
After extracting, obtain solution of extract in aqueous solvent, when it uses, both solution of extract directly can be used; Also can, except after desolventizing, re-use extract.
Preferably, after comprising that Senecio plant 5%～50%, Verbenaceae 20%～70%, nightshade 5%～50% and serissa plants 20%～70% are mixed, take water as solvent, be heated to 70 ℃～100 ℃ extractions.
More preferably, be 1 minute～24 hours heat time heating time.
Another object of the present invention is to provide the application of multifunctional plant extractive composition in preparing cosmetics, medicine and hygienic article.
Multifunctional plant extractive of the present invention is for the production of hygienic article, especially be suitable for producing disposable sanitary articles, so-called disposable sanitary articles, i.e. use once abandons afterwards, directly or indirectly contact with human body, and for reaching Human Physiology health or health care (sterilization or antibacterial) the various daily living articles that object is used, product characteristics can be solids, can be also liquid.As nonrecoverable glove or fingerstall; Napkin; Wet tissue; Wet sanitary napkins; Telephone film; Medicated cap; Mask; Underwear; Gynecologic menstrual hygienic article (comprising sanitary pad); The Excreta hygienic article such as diaper; Condom etc.Multifunctional plant extractive of the present invention both can be processed above-mentioned hygienic article sterilization, antibacterial bacteriostatic, also can be attached to above-mentioned hygienic article and use together.
Another object of the present invention is to provide a kind of bactericidal composition, it is characterized in that, comprises the compositions of aforesaid multifunctional plant extractive, and its weight percentage is 0.1～90%.
Preferably, also comprise pharmaceutic adjuvant, can be applied in cosmetics adjuvant or the hygienic article adjuvant of skin.Cosmetics adjuvant or hygienic article Optimization of Adjuvant that pharmaceutic adjuvant maybe can be applied in skin adopt auxiliary element or the functional component of not damaging, not stimulating human body skin, mucosa, can be used as external curing medicine and/or be prevention, and/or be that the multi-form or object of the disinfectant, daily-use sanitary articles for use, cosmetics, medicine etc. of auxiliary treatment is used.Other auxiliary elements in bactericidal composition of the present invention or other functional components can be one or more.
Bactericidal composition of the present invention can be for multi-form, comprises prepared by the conventional products type form such as solution, ointment, foam formulations, gel, oil preparation, cream, lotion, paste, tincture and external pulvis and for skin, mucosa externally applied product.
Bactericidal composition in the present invention is applicable to Whole Body skin, body discharges, genitals's externally used antimicrobial, antipruritic, antiinflammatory, detumescence.The present composition can be for damaged antibacterial when hemorrhage of skin surface, mucosa.
Senecio, feverfew, is widely distributed in the whole world, and all there is distribution each provinces and regions of China.Draft, undershrub or shrub; Leaf alternate, base is raw sometimes; The life of head inflorescence list or bunchy, color is various, conventionally the special-shaped flower of tool; Ligulate flower is solid, disc floret tubulose, 5 fissures; Phyllary 1 row, but base portion often has the outer bract of several pieces less; Achene is cylindrical and have rib; Pappus enriches or minority, or sometimes without pappus.Senecio plant of the present invention is selected from one or more in Senecio faberii Hemsl, volume river Herba Senecionis Scandentis, Herba Senecionis asperifolii, Senecio cannabifolius, chrysanthemum shape Herba Senecionis Scandentis, Senecio dianthus, tree shade Herba Senecionis Scandentis, Herba Senecionis Scandentis, purple back of the body Herba Senecionis Scandentis and Guangdong, Fujian Herba Senecionis Scandentis.
Verenaceae, dicotyledon, is distributed in global tropical and subtropical zone, and all there is distribution China various places, are various places on the south the Changjiang river main product.One or more in one or more in Clerodendron plant in the preferred Verenaceae of the present invention, verbena or the mixture of Clerodendron plant and verbena.
Clerodendron plant of the present invention is selected from one or more in spending of Herba Clerodendri fortunati, Cheng paulownia, Radix clerodendri fragrantis (Radix Clerodendri Philippini), Caulis et folium clerodendri bungei, Folium Isatidis, Radix Clerodendri kwangtungensis (Clerodendrum kwang), clerodendron trichotomum, gray wool Folium Isatidis, lindley glorybower herb, bitter Lang Shu, Clerodendrum henryi Pei and three.
Verbena of the present invention is selected from Herba Verbenae.
Nightshade of the present invention is selected from Fructus Solani procumbentis, bitter thorn, Fructus Solani Dulcamarae, Herba Solani Nigri, Radix Solani ferocis, cattle Fructus Solani melongenae and spends less one or more in Herba Solani Nigri.
Serissa plants in the present invention is selected from one or both the mixture in Radix Serissae and Serissa foetida.
For the plant parts of compositions of the present invention, can be selected from any position of plant.Wherein serissa plants especially preferentially adopts the root of plant.For extracting the plant parts of compositions of the present invention, can be fresh raw meal, can be also dried plant.
The present invention is directed to the limitation of above chemosynthesis antimicrobial product, the skin, the mucosa bactericidal composition that provide a kind of natural active products to prepare, human body skin, mucosa can effectively be prevented and treat to said composition by antibacterial or fungus-caused pathological changes.
The feature of multifunctional compositions of the present invention is:
1) green, nature, non-stimulated, can be long-time, large area used: this compositions property chosen and natural plants and extract thereof, do not add any compound essence, synthetic food color, spice, use and there is no zest, can be for a long time, large area used.
2) antibacterial, antipruritic ability is strong: the plant extract in this compositions can be effectively antibacterial, to causing that malignant bacteria and the fungus of human body various diseases has very strong antimicrbial power.The present invention carries out effectively antibacterial, antiinflammatory cure rate and reaches 95%, mucosal inflammation sick by the fungus-caused skin surface such as the malignant bacterias such as staphylococcus aureus, Candida albicans.Meanwhile, in using present composition process, this product is carried out effectively antipruritic to skin, body discharges, genitals's mucosa pruritus.
3) speed that takes effect is fast: for using the present composition can be obviously antipruritic in 6 hours, be used 1-2 every day, and common 6-15 time (3-8 day) can cure the inflammation that the microorganisms such as antibacterial, fungus cause.With like product, compare, its fungistatic effect (for example eliminating vagina inflammation) surpasses existing like product, and its consumption only needs the 1/5-1/3 of these like products can reach identical effect.
4) processing technology is simple, cost is low: this product can adopt conventional comparatively gentle production technology to extract, and cost of manufacture is low and simple, is suitable for the large-scale production of said composition.
The specific embodiment
Below in conjunction with embodiment, the present invention is described in detail:
Embodiment 1, medicinal bactericidal composition, solution dosage:
10 kilograms of draft raw materials, comprise by weight proportion: Radix clerodendri fragrantis (Radix Clerodendri Philippini) herb 5%, Herba Verbenae herb 40%, Senecio dianthus part of stem leaf 5%, herb of Herba Solani Nigri 10%, Radix Serissae herb 15%, Serissa foetida herb 25%.Jointly put into 80 kg water, be heated to 85 ℃, heat 4 hours, solid-liquid separation, obtains extract solution.Extract solution heating evaporation water until in extract containing plant extract and 94 weight parts waters of 6 weight portions, can be used for antibacterial.This combination dosage form is solution.This compositions can be contained in spray bottle, for portable Antimicrobial sanitation articles for use; Also can be used for soaking medicinal cotton wool, cotton wool can be for the antibacterial use of wound or inflammation.
Get the present embodiment compositions of 7 parts of 180ml, according to standard GB/T 15979-2002 appendix C, carry out antibacterial and fungus bacteriostatic test.What antibacterial was chosen is the important pathogen staphylococcus aureus that causes human infection.Fungus has adopted Candida albicans, and it is a kind of fungus, is conventionally present in the oral cavity of human body, upper respiratory tract, intestinal and vagina etc.Test temperature is 20 ± 1 ℃, 2,5,10,20 minutes antibacterial time.Test repeats 3 times.The plant extract compositions of experiment results proved the present embodiment gained was 100% to the bacteriostasis rate of staphylococcus aureus and Candida albicans from 2-20 minute.According to standard GB/T 15979-2002, this compositions is 100% to the bacteriostasis rate of staphylococcus aureus and Candida albicans.
Embodiment 2:
Multifunctional plant composition, comprises by weight proportion: Radix Clerodendri kwangtungensis (Clerodendrum kwang) leaf 25%, tree shade Herba Senecionis Scandentis herb 40%, herb of Herba Solani Nigri 5%, Serissa foetida herb 30%.
Embodiment 3: daily antibacterial, preserving moisture and protecting skin compositions, paste cosmetics.
10 kilograms of draft raw materials, wherein comprise by weight percentage: Herba Senecionis Scandentis herb 5%; Clerodendron trichotomum herb 10%; Herb of Herba Solani Nigri 5%; Radix Serissae herb 70%.
By 70 kg water, as solvent, be heated to 70 ℃, heat 20 hours, solid-liquid separation, obtains extract solution.Extract solution, with after heating evaporation water, obtains paste plant extract.
By the plant extract of 1 weight portion, add the vaseline of the skin moisture-keeping effect of adjuvant 99 weight portions to make compositions, be heated to 65 ℃ and fully mix, then cooling at normal temperatures, obtain daily antibacterial, preserving moisture and protecting skin paste cosmetics.
Embodiment 4: gentle antibacterial, antipruritic, blast hair-washing composition, and transparency liquid:
5 kilograms of draft raw materials, wherein comprise by weight percentage: Herba Senecionis asperifolii herb 25%; Herba Verbenae herb 35%; Radix Solani ferocis fruit 20%; Serissa foetida herb 20%.By 3 kg water, as solvent, be heated to 65 ℃, heat 2 hours, solid-liquid separation, obtains extract solution.Extract solution, with after heating evaporation water, obtains antibacterial, the antipruritic plant extract of paste.
Prepare antibacterial, the antipruritic plant extract of 2 weight portions; adjuvant comprises: the water of 62 weight portions; the cocamido propyl betaine of the blowing agent of 20 weight portions, conditioner effect (CAB-35); 10 weight portion decontaminations, emulsifying agent N-acyl glutamic acid sodium AGA; the anti-hard water agent oleoyl aminoacid sodium of 4.7 weight portions; the hair brightening agent chamomile extract of 1 weight portion, the thickening agent sodium chloride of 0.3 weight portion.
First water and cocamido propyl betaine are heated to 50 ℃ of fully mixing; under stirring, add successively N-acyl glutamic acid sodium AGA; oleoyl aminoacid sodium; the plant extract and the chamomile extract that after mix homogeneously, add the present embodiment to make; finally add sodium chloride and regulate denseness; just obtained antipruritic, antibacterial, blast hair-washing composition, and be transparent liquid.
Embodiment 5:
Multifunctional plant composition, comprises by weight percentage: three colored herbs 70%, chrysanthemum shape Herba Senecionis Scandentis herb 5%, Radix Solani ferocis herb 5%, Serissa foetida herb 20%.
Embodiment 6: multifunctional plant extractive composition.
10 kilograms of draft raw materials, wherein comprise by weight percentage: purple back of the body Herba Senecionis Scandentis herb 50%; Herba Clerodendri fortunati herb 20%; Fructus Solani Dulcamarae herb 10%; Radix Serissae herb 20%.
By 120 kg water, be divided into four parts as solvent, every kind of plant is put into a water, is heated to respectively 95 ℃, heats 22 hours, and solid-liquid separation, obtains four parts of extract solutions.Four parts of extract solution mixing post-heating are evaporated to the compositions containing plant extract weight content is 90%, water weight content is 10%.
Embodiment 6: multifunctional plant extractive composition.
10 kilograms of draft raw materials, wherein comprise by weight percentage: Guangdong, Fujian Herba Senecionis Scandentis herb 30%; Herba Verbenae herb 25%; Fructus Solani procumbentis herb 10%; Serissa foetida herb 35%.
By 200 kg water, as solvent, be heated to 95 ℃, heat 10 hours, solid-liquid separation, obtains extract solution.Extract solution with heating evaporation water to the compositions that is 70% containing plant extract weight, water weight is 30%.
Embodiment 7: multifunctional plant extractive composition.
10 kilograms of draft raw materials, wherein comprise by weight percentage: Guangdong, Fujian Herba Senecionis Scandentis herb 30%; Herba Verbenae herb 25%; Fructus Solani procumbentis herb 10%; Serissa foetida herb 35%.
By 30 kg water, as solvent, be heated to 95 ℃, heat 5 minutes, solid-liquid separation, the compositions that must be 0.1% containing plant extract weight percentage, water weight percentage is 99.9%.
Embodiment 8: multifunctional plant extractive composition.
10 kilograms of draft raw materials, wherein comprise by weight percentage: Senecio cannabifolius herb 10%; Herba Verbenae herb 20%, gray wool Folium Isatidis 35%; Bitter thorn herb 7%, herb of Herba Solani Nigri 8%; Serissa foetida herb 12%, Radix Serissae root 8%.
By 50 kg water, as solvent, be heated to 95 ℃, heat 24 hours, solid-liquid separation, obtains extract solution.Extract solution heating evaporation is to the compositions that is 36% containing plant extract weight percentage, water weight percentage is 64%.
Embodiment 9: multifunctional plant extractive composition.
10 kilograms of draft raw materials, wherein comprise by weight percentage: Senecio cannabifolius herb 4%, Senecio faberii Hemsl herb 5%, Senecio dianthus stem and leaf 2%; Herba Verbenae herb 10%, lindley glorybower herb herb 28%; Fructus Solani Dulcamarae herb 17%; Serissa foetida herb 10%, Radix Serissae 24%.
By 50 kg water, as solvent, be heated to 100 ℃, heat 15 hours, solid-liquid separation, obtains extract solution.Extract solution with heating evaporation water to the compositions that is 80% containing plant extract weight, water weight is 20%.
Embodiment in the present invention, only for the present invention will be described, does not form the restriction to claim scope, and other substituting of being equal in fact that those skilled in that art can expect, all in protection domain of the present invention.
Claims (10)
1. antibacterial plant compositions, is characterized in that, comprises by weight proportion: Radix clerodendri fragrantis (Radix Clerodendri Philippini) herb 5%, Herba Verbenae herb 40%, Senecio dianthus part of stem leaf 5%, herb of Herba Solani Nigri 10%, Radix Serissae herb 15%, Serissa foetida herb 25%.
2. the application of antibacterial plant compositions claimed in claim 1 in preparing antibacterial.
3. the application in one or both the antibacterial of antibacterial plant compositions according to claim 2 in preparing anti-Staphylococcus aureus and Candida albicans.
4. antibacterial plant extractive composition, it is characterized in that, the compositions of described extract is from comprise Radix clerodendri fragrantis (Radix Clerodendri Philippini) herb 5% according to weight percentage, Herba Verbenae herb 40%, Senecio dianthus part of stem leaf 5%, herb of Herba Solani Nigri 10%, Radix Serissae herb 15%, in the raw material of Serissa foetida herb 25% proportioning, extraction obtains.
5. antibacterial plant extractive composition according to claim 4, is characterized in that, described extract is for being used aqueous solvent to extract.
6. antibacterial plant extractive composition according to claim 5, it is characterized in that, to comprise Radix clerodendri fragrantis (Radix Clerodendri Philippini) herb 5%, Herba Verbenae herb 40%, Senecio dianthus part of stem leaf 5%, herb of Herba Solani Nigri 10%, Radix Serissae herb 15%, after Serissa foetida herb 25% mixes, take water as solvent, be heated to 70 ℃～100 ℃ extractions.
7. antibacterial plant extractive composition according to claim 6, is characterized in that, be 1 minute～24 hours heat time heating time.
8. the application in preparing cosmetics, medicine and hygienic article according to the antibacterial plant extractive composition described in the arbitrary claim of claim 4 to 7.
9. bactericidal composition, is characterized in that, comprises the antibacterial plant extractive composition described in the arbitrary claim of claim 4～7, and its weight percentage is 0.1～90%.
10. bactericidal composition according to claim 9, is characterized in that, also comprises pharmaceutic adjuvant, can be applied in cosmetics adjuvant or the hygienic article adjuvant of skin.
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| CN1326679A (en) * | 2001-06-22 | 2001-12-19 | 丁小武 | Pure plant disease treatment insecticide and its producing method |
| CN1397686A (en) * | 2002-08-20 | 2003-02-19 | 张天银 | Superthin composite medicinal paper and its making technology |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1326679A (en) * | 2001-06-22 | 2001-12-19 | 丁小武 | Pure plant disease treatment insecticide and its producing method |
| CN1397686A (en) * | 2002-08-20 | 2003-02-19 | 张天银 | Superthin composite medicinal paper and its making technology |
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| 周邦靖等.106种中药对肺炎克雷伯氏菌抗菌作用的实验观察.《成都中医药大学学报》.1998,第21卷(第2期), * |
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