CN103169839B - Preparation method of traditional Chinese medicine preparation for treating deficiency and internal injury and prepared traditional Chinese medicine preparation - Google Patents
Preparation method of traditional Chinese medicine preparation for treating deficiency and internal injury and prepared traditional Chinese medicine preparation Download PDFInfo
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Abstract
The invention relates to a preparation method of a traditional Chinese medicine preparation for treating deficiency and internal injury and the traditional Chinese medicine preparation prepared according to the method. The preparation method comprises the following steps: taking ginseng, barbary wolfberry fruit, deer horn gelatin, tortoise-plastron glue, processed tuber fleeceflower root, Chinese magnoliavine fruit, common yam rhizome, walnut seed and radix salviae miltiorrhizae, respectively extracting the ginseng and other medicinal materials by adopting an ultrasonic technology, further combining two extracts into one and processing to prepare traditional Chinese medicine ointment. According to the preparation method disclosed by the invention, the medicinal materials are separately extracted by adopting the ultrasonic technology, and then the two extracts are combined into one, so that the effective ingredients in the preparation can be effectively ensured. The prepared traditional Chinese medicine preparation can be directly taken without decoction, has the advantages of mild medicine property, short taking treatment course, rapid onset of action, high cure rate, no toxicity and no side effects and can be widely used for treating patients with the deficiency and the internal injury.
Description
Technical field
The invention belongs to Chinese medicine preparation technical field, be specifically related to a kind ofly treat the Chinese medicine preparation preparation method of deficient impairment caused by overstrain and according to the Chinese medicine preparation of the method gained.
Background technology
Impairment caused by overstrain is deficient causes a disease, and mainly refers to excessive labour, the factor such as a tax on one's mind, causes internal organs QI and blood impaired, and negative and positive are become estranged, and makes healthy energy loss and disease occurs.As kidney governing bones, the skeleton inanition of suffering from a deficiency of the kidney, turbid the taking advantage of a loophole of wind and cold expectorant invaded and the raw tuberculosis of bone and joint; Deficiency of kidney yin, hyperactivity of deficient fire, bright Tianjin is expectorant, phlegm-fire condenses and raw scrofula, and after scrofula healing, can recur because body is empty.Deficiency of the liver and kindey, cold-damp is invaded outward, cohesion meridians, numbness plug is obstructed, and QI-blood circulation does not freely form necrosis.Excessive fatigue, standing for a long time walking for a long time makes muscular strain, can cause lower limb nodular varicosity etc.At present, the deficient Chinese patent medicine prescription for the treatment of impairment caused by overstrain is more, but great majority are to adopt traditional handicraft to make pill or decoction, while taking, comparatively bother.
Summary of the invention
For solving the problems of the technologies described above, the present invention proposes one
Technical scheme of the present invention is: a kind of Chinese medicine preparation preparation method for the treatment of deficient impairment caused by overstrain, and its processing step is as follows:
(1) get Radix Ginseng 1-2 part, at pressure 0.5Mpa, under 40 ℃ of conditions of temperature, adopt ultrasonic extraction method medicinal liquid, according to solid-to-liquid ratio, 1:5-8 adds water, and extraction time is 0.5-1h.Adopt supercritical ultrasonics technology at least to extract 3 times, merge extractive liquid,, leaves standstill, and filters through high speed centrifuge, obtains Radix Ginseng extractive solution.
(2) in the Radix Ginseng extractive solution of step (1) gained, melt enters 1 part, Colla cornus cervi 1-2 part, Testudinis angle glue, obtains mixed liquor A.
(3) get Fructus Lycii 7-8 part, Radix Polygoni Multiflori Preparata 4-5 part, Fructus Schisandrae Chinensis 4-5 part, Rhizoma dioscoreae (parched) 10-11 part, Semen Juglandis 4-5 part, Radix Salviae Miltiorrhizae 2-3 part, adopt ultrasonic extraction method medicinal liquid, according to solid-to-liquid ratio, 1:3-5 adds water, and extraction time is 0.5-1h.Adopt supercritical ultrasonics technology at least to extract 2 times, merge extractive liquid,, leaves standstill, and filters through high speed centrifuge, obtains mixed liquid B.
(4) mixed liquor A that adds step (2) to obtain in the mixed liquid B obtaining in step (3), after high speed centrifuge remove impurity is filtered, is placed in the filtrate of gained that in concentrator, to be concentrated into proportion be 1.18-1.23, obtains total mixed liquor C.
(5) in the total mixed liquor C making in step (4), adding proportion is 1.38 refined honey, mixes, and boils in the time that proportion is 1.33-1.38 and filters, and obtains Chinese medicine preparation.The addition of described refined honey is 3-4 times of total mixed liquor C weight.
By standing the Chinese medicine preparation of above-mentioned gained, embedding.
The manufacture method of described refined honey is: by Mel refine in the vacuum of temperature 80-85 ℃, to proportion be 1.38, obtain refined honey.
The Chinese medicine preparation of the deficient impairment caused by overstrain for the treatment of treatment is according to the product of said method gained.
Chinese medicine is thought: asthenia is the meaning of deficient impairment caused by overstrain, is also all empty not enough and summaries of the various diseases that produces of the five internal organs, and all congenital defects, lack of proper care after one's birth, and sick mistake for a long time supported, healthy energy damage, and prolonged deficiency is multiple, shows all genus asthenia category of various weak syndromes.
According to above-mentioned theory, treating deficient impairment caused by overstrain should be take conditioning the five internal organs as main.In the present invention, Testudinis angle leads to conception vessel and nourishing YIN for suppressing the hyperactive YANG, and kidney tonifying promotes the production of body fluid; Cornu Cervi dredging DU Meridian arteries and veins and strengthening yang and invigorating kidney, strengthening the tendons and bones, share to link up to appoint and superintends and directs, high nourishing YIN sun; Separately join ginseng qi-tonifying with strengthening the spleen and nourishing the stomach, lung benefiting promotes the production of body fluid; Fructus Lycii nourishes blood with nourishing the liver and kidney, replenishing vital essence to improve eyesight.Radix Polygoni Multiflori Preparata, Rhizoma Dioscoreae, Semen Juglandis nourish blood with nourishing the liver and kidney, replenishing vital essence to improve eyesight, and Radix Salviae Miltiorrhizae, Fructus Schisandrae Chinensis are promoted blood circulation and are nourished blood.Full side share, Yin grows while yang is generating, and gas-solid blood fills, therefore asthenia patient You Nengqu is imitated.
Preparation method provided by the invention adopts ultrasonic technology to separate extraction to medical material, and the method finally uniting two into one effectively guarantees the effective ingredient of preparation.The Chinese medicine preparation making can directly be taken, fried without going again, its property of medicine gentleness, take short treating period, instant effect, cure rate high, have no side effect, can be widely used in the deficient impairment caused by overstrain patient for the treatment of.
The specific embodiment
Illustrate the present invention below in conjunction with embodiment.
Embodiment 1
Treat the Chinese medicine preparation of deficient impairment caused by overstrain, its step of preparation process is as follows:
(1) get Radix Ginseng 10.56g, at pressure 0.5Mpa, under 40 ℃ of conditions of temperature, according to solid-to-liquid ratio, 1:8 adds water, and adopts ultrasonic extraction method 30min, filters.In filtering residue according to solid-to-liquid ratio 1:6 add water ultrasonic repeat extract once, the time is 30min, filter.Again in filtering residue according to solid-to-liquid ratio 1:5 add water ultrasonic repeat extract once, time 30min, filter.The extracting solution of three times is mixed, leave standstill, filter through high speed centrifuge, obtain Radix Ginseng extractive solution.
(2) in the Radix Ginseng extractive solution of step (1) gained, melt enters Colla cornus cervi 10.56g, Testudinis angle glue 10.56g, obtains mixed liquor A.
(3) get Fructus Lycii 73.92g, Radix Polygoni Multiflori Preparata 42.24g, Fructus Schisandrae Chinensis (processed with wine) 42.24g, Rhizoma dioscoreae (parched) 105.6g, Semen Juglandis 42.24g, Radix Salviae Miltiorrhizae 21.12g, according to solid-to-liquid ratio, 1:5 adds water, and adopts ultrasonic extraction method 30min, filters.In filtering residue according to solid-to-liquid ratio 1:3 add water ultrasonic repeat extract once, the time is 30min, filter.Merge extractive liquid,, leaves standstill, and filters through high speed centrifuge, obtains mixed liquid B.
(4) mixed liquor A that adds step (2) to obtain in the mixed liquid B obtaining in step (3), after high speed centrifuge remove impurity is filtered, is placed in the filtrate of gained that in concentrator, to be concentrated into proportion be 1.18, obtains total mixed liquor C.
(5) in the total mixed liquor C making in step (4), adding proportion is 1.38 refined honey, mixes, and boiling to proportion is to filter for 1.33 o'clock, obtains Chinese medicine preparation.The addition of described refined honey is 3 times of total mixed liquor C weight.
By standing the Chinese medicine preparation of above-mentioned gained, embedding, be finished product for subsequent use.
The manufacture method of refined honey is: by Mel refine in 80 ℃ of vacuum, to proportion be 1.38, obtain refined honey.
Embodiment 2
Treat the Chinese medicine preparation of deficient impairment caused by overstrain, its step of preparation process is as follows:
(1) get Radix Ginseng 20.36g, at pressure 0.5Mpa, under 40 ℃ of conditions of temperature, according to solid-to-liquid ratio, 1:8 adds water, and adopts ultrasonic extraction method 30min, filters.In filtering residue according to solid-to-liquid ratio 1:6 add water ultrasonic repeat extract once, the time is 60min, filter.Again in filtering residue according to solid-to-liquid ratio 1:5 add water ultrasonic repeat extract once, time 60min, filter.The extracting solution of three times is mixed, leave standstill, filter through high speed centrifuge, obtain Radix Ginseng extractive solution.
(2) in the Radix Ginseng extractive solution of step (1) gained, melt enters Colla cornus cervi 40.72g, Testudinis angle glue 20.36g, obtains mixed liquor A.
(3) get Fructus Lycii 162.88g, Radix Polygoni Multiflori Preparata 101.8g, Fructus Schisandrae Chinensis (processed with wine) 101.8g, Rhizoma dioscoreae (parched) 223.96g, Semen Juglandis 101.8g, Radix Salviae Miltiorrhizae 61.08g, according to solid-to-liquid ratio, 1:5 adds water, and adopts ultrasonic extraction method 60min, filters.In filtering residue according to solid-to-liquid ratio 1:3 add water ultrasonic repeat extract once, the time is 60min, filter.Merge extractive liquid,, leaves standstill, and filters through high speed centrifuge, obtains mixed liquid B.
(4) mixed liquor A that adds step (2) to obtain in the mixed liquid B obtaining in step (3), after high speed centrifuge remove impurity is filtered, is placed in the filtrate of gained that in concentrator, to be concentrated into proportion be 1.23, obtains total mixed liquor C.
(5) in the total mixed liquor C making in step (4), adding proportion is 1.38 refined honey, mixes, and boiling to proportion is to filter for 1.38 o'clock, obtains Chinese medicine preparation.The addition of described refined honey is 4 times of total mixed liquor C weight.
By standing the Chinese medicine preparation of above-mentioned gained, embedding, be finished product for subsequent use.
The manufacture method of refined honey is: by Mel refine in 85 ℃ of vacuum, to proportion be 1.38, obtain refined honey.
Claims (3)
1. a Chinese medicine preparation preparation method for the treatment of deficient impairment caused by overstrain, its processing step is as follows:
(1) get Radix Ginseng 1-2 part, at pressure 0.5Mpa, under 40 ℃ of conditions of temperature, adopt ultrasonic extraction method medicinal liquid, according to solid-to-liquid ratio, 1:5-8 adds water, and extraction time is 0.5-1h; Adopt supercritical ultrasonics technology at least to extract 3 times, merge extractive liquid,, leaves standstill, and filters through high speed centrifuge, obtains Radix Ginseng extractive solution;
(2) in the Radix Ginseng extractive solution of step (1) gained, melt enters 1 part, Colla cornus cervi 1-2 part, Testudinis angle glue, obtains mixed liquor A;
(3) get Fructus Lycii 7-8 part, Radix Polygoni Multiflori Preparata 4-5 part, Fructus Schisandrae Chinensis 4-5 part, Rhizoma dioscoreae (parched) 10-11 part, Semen Juglandis 4-5 part, Radix Salviae Miltiorrhizae 2-3 part, adopt ultrasonic extraction method medicinal liquid, according to solid-to-liquid ratio, 1:3-5 adds water, and extraction time is 0.5-1h; Adopt supercritical ultrasonics technology at least to extract 2 times, merge extractive liquid,, leaves standstill, and filters through high speed centrifuge, obtains mixed liquid B;
(4) mixed liquor A that adds step (2) to obtain in the mixed liquid B obtaining in step (3), after high speed centrifuge remove impurity is filtered, is placed in the filtrate of gained that in concentrator, to be concentrated into proportion be 1.18-1.23, obtains total mixed liquor C;
(5) in the total mixed liquor C making in step (4), adding proportion is 1.38 refined honey, mixes, and boils in the time that proportion is 1.33-1.38 and filters, and obtains Chinese medicine preparation; The addition of described refined honey is 3-4 times of total mixed liquor C weight.
2. Chinese medicine preparation preparation method according to claim 1, is characterized in that, the manufacture method of described refined honey is: by Mel refine in the vacuum of temperature 80-85 ℃, to proportion be 1.38, obtain refined honey.
3. the Chinese medicine preparation of the deficient impairment caused by overstrain for the treatment of that prepared by preparation method according to claim 1 and 2.
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