CN101485859B - Chinese medicine for treating specific oligospermatism - Google Patents
Chinese medicine for treating specific oligospermatism Download PDFInfo
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- CN101485859B CN101485859B CN2009100144280A CN200910014428A CN101485859B CN 101485859 B CN101485859 B CN 101485859B CN 2009100144280 A CN2009100144280 A CN 2009100144280A CN 200910014428 A CN200910014428 A CN 200910014428A CN 101485859 B CN101485859 B CN 101485859B
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Abstract
The invention discloses a traditional Chinese medicine for treating idiopathic oligospermatism, which is a traditional Chinese medicine pill prepared from prepared rehmannia rhizome, Chinese yam, Polygonum multiform, dogwood fruit, field dobber, medlar, Schisandra chinensis, root barks of tree peony, golden hop, eucommia barks, semen plantaginis, milkvetch seeds, glossy privet fruit, mulberry fruit, ginseng, Poria cocos, cumin, deerhorn glue, Morinda officinalis, geckoes, tuber onion seeds, leeches, Amomum villosum and Asarum sieboldi which are taken as raw materials. The medicine for treating idiopathic oligospermatism has the advantages that the medicine has short treatment period, good effect, and no toxic and side reaction, has the cure rate as high as 53.8 percent, and has total effective rate of 92.2 percent.
Description
Technical field
The invention belongs to the Chinese medicine technical field of pharmaceuticals, be specifically related to a kind of Chinese medicine medicine for the treatment of specific oligospermatism.
Background technology
Specific oligospermatism is one of common difficult disease of andrology.Its etiology and pathogenesis is that natural endowment deficiency, kidney qi are not filled, in addition the day after tomorrow insufficiency of generating and transforming QI and blood, essence become homeless support due to.At present, adopt Drug therapys such as clomiphene, methyltestosterone and prednisone more, but the low side effect in addition of cure rate, curative effect is undesirable.
Summary of the invention
The Chinese medicine medicine of the treatment specific oligospermatism that the purpose of this invention is to provide a kind for the treatment of both the principal and secondary aspects of a disease, have no side effect, cure rate is high.
Solution of the present invention is based on pathogenetic understanding and the Therapeutic Principle of motherland's medical science to specific oligospermatism, with reference to ancient, modern pharmacological research achievement, from motherland's medical treasure-house, filter out kidney-replenishing, nourishing kidney-yin, benefit superintend and direct appoint, the natural Chinese medicine in replenishing essence palace, by the theory of Chinese medical science prescription, skim the cream off milk, make its performance kidney-tonifying and sperm-producing, promote the synthetic effect of sperm, specific oligospermatism is had the effect of healing.
Medicine of the present invention is made (consumption is a weight portion) by following component:
Radix Rehmanniae Preparata 30 Rhizoma Dioscoreaes 15 Radixs Polygoni Multiflori 12 Fructus Corni 15 Semen Cuscutae 15 Fructus Lycii 15 Fructus Schisandrae Chinensis 10
Cortex Moutan 6 Fols lupulis 12 Cortexs Eucommiae 15 Semen Plantaginiss 10 Semen Astragali Complanatis 15 Fructus Ligustri Lucidi 15 Fructus Mori 15
A pair of Leek 20 of Radix Ginseng 10 Poria 15 Fructus Foeniculi, 15 Colla cornus cervis, 10 Radix Morindae Officinaliss, 15 Geckos
Hirudo 10 Fructus Amomis 10 Herba Asaris 6
Above-mentioned each component is made Chinese medicine pill according to a conventional method:
With above-mentioned each component mixing, pulverize, cross 80 mesh sieves, water is cooked adhesive and is made Chinese medicine pill, 80 ℃ of dryings 1 hour, packing then.
Medicine of the present invention name for: educate smart red.
Medicine of the present invention is educated smart red clinical use result and is shown that following advantage is arranged:
1, the present invention selects the natural Chinese medicines raw material for use, and each component meets pharmaceutical control law regulation, utilizes the comprehensive function of the Chinese medicine of respectively distinguishing the flavor of, and specific oligospermatism is had the effect of healing, does not have chemical sweeting agent, and is nontoxic to human body.
2, the present invention distinguish the flavor of little sweet, no bitterness sense, taking convenience.
For showing the curative effect of medicine of the present invention, the present invention selects case through clinical observation for many years, and the age is 25-40 year.156 examples are organized in treatment, 1～3 year person's 112 example of the course of disease, 4～6 years person's 30 examples, 7～10 years person's 14 examples; Matched group 58 examples, 1～3 year person's 40 example of the course of disease, 4～6 years person's 12 examples, 7～10 years person's 6 examples.
Diagnostic criteria: do not take contraceptives, live together and do not educate more than 1 year, wife does not have obvious cause of infertility on inspection, microscopy bridegroom's or husband's side seminal fluid 2-3 time, and sperm concentration all below 2,000 ten thousand/ml, is got rid of the oligospermatism that sure reason is arranged.
Criterion of therapeutical effect: cure: more than sperm concentration 2,500 ten thousand/ml; Effectively: between sperm concentration 2000-2500 ten thousand/ml; Take a turn for the better: invalid: sperm concentration and the preceding no change or very little of treatment.
Statistical method: utilization X 2 test, Ridit analytical statistics method detect clinical cure rate, effective percentage, total effective rate between two groups.
Therapeutic Method: treatment group: educate smart pellet, every clothes 12 grams, day clothes 3 times, 90 days was 1 course of treatment, serve on 2 courses of treatment; Matched group: the Western medicine clomiphene, every clothes 50mg, 3 times on the 1st, 90 days was 1 course of treatment, serve on 2 courses of treatment.
Therapeutic outcome: two groups of curative effect concrete conditions see Table 1,2.Learn by statistics and handle, P＜0.05, significant difference has comparability.
Table 1 seminal fluid density curative effect relatively
Ridit analyzes: U=2.408 P＜0.05
Other standard influence of table 2 seminal fluid relatively
Curative effect is relatively: the result shows, educates smart red evident in efficacyly, is better than matched group (P＜0.01).
Toxicity: since this medicinal application, through patient's terminal observation of curative effect, find no obvious toxicity, anaphylaxis and zest, row kidney merit, liver function, blood, routine urianlysis, all no abnormal variation illustrates and educates smart pellet to be applied to clinical be safe and reliable.
The invention has the beneficial effects as follows short treating period, effective, no toxicity, cure rate are up to 53.8%, and total effective rate reaches 92.2%.
The specific embodiment
Take by weighing raw material (gram) by following proportioning
Radix Rehmanniae Preparata 30 Rhizoma Dioscoreaes 15 Radixs Polygoni Multiflori 12 Fructus Corni 15 Semen Cuscutae 15 Fructus Lycii 15 flavor 10
Cortex Moutan 6 Fols lupulis 12 Cortexs Eucommiae 15 Semen Plantaginiss 10 Semen Astragali Complanatis 15 Fructus Ligustri Lucidi 15 Fructus Mori 15
A pair of Leek 20 of Radix Ginseng 10 Poria 15 Fructus Foeniculi, 15 Colla cornus cervis, 10 Radix Morindae Officinaliss, 15 Geckos
Hirudo 10 Fructus Amomis 10 Herba Asaris 6
Above-mentioned each component is made Chinese medicine pill according to a conventional method:
With above-mentioned each component mixing, pulverize, cross 80 mesh sieves, water is cooked adhesive and is made Chinese medicine pill, 80 ℃ of dryings 1 hour, packing then, promptly.
Claims (1)
1. a Chinese medicine medicine for the treatment of specific oligospermatism is characterized in that it is the Chinese medicine pill of being made by following raw materials by weight proportions: Radix Rehmanniae Preparata 30, Rhizoma Dioscoreae 15, the Radix Polygoni Multiflori 12, Fructus Corni 15, Semen Cuscutae 15, Fructus Lycii 15, Fructus Schisandrae Chinensis 10, Cortex Moutan 6, Fols lupuli 12, the Cortex Eucommiae 15, Semen Plantaginis 10, Semen Astragali Complanati 15, Fructus Ligustri Lucidi 15, Fructus Mori 15, Radix Ginseng 10, Poria 15, Fructus Foeniculi 15, Colla cornus cervi 10, Radix Morindae Officinalis 15, Gecko is a pair of, Leek 20, Hirudo 10, Fructus Amomi 10, Herba Asari 6; With the said medicine mixing, pulverize, cross 80 mesh sieves, water is cooked adhesive and is made Chinese medicine pill, 80 ℃ of dryings 1 hour, packing then, promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100144280A CN101485859B (en) | 2009-02-15 | 2009-02-15 | Chinese medicine for treating specific oligospermatism |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100144280A CN101485859B (en) | 2009-02-15 | 2009-02-15 | Chinese medicine for treating specific oligospermatism |
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| Publication Number | Publication Date |
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| CN101485859A CN101485859A (en) | 2009-07-22 |
| CN101485859B true CN101485859B (en) | 2011-09-07 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2009100144280A Expired - Fee Related CN101485859B (en) | 2009-02-15 | 2009-02-15 | Chinese medicine for treating specific oligospermatism |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103356920A (en) * | 2012-03-26 | 2013-10-23 | 张兴国 | Semen generating and activating soup |
| CN103169839B (en) * | 2013-04-12 | 2014-05-28 | 山东方健制药有限公司 | Preparation method of traditional Chinese medicine preparation for treating deficiency and internal injury and prepared traditional Chinese medicine preparation |
| CN103432381B (en) * | 2013-06-28 | 2014-10-15 | 袁国宪 | Male infertility (non-organic pathologic change) treatment traditional Chinese medicine composition |
| CN110801485A (en) * | 2018-08-06 | 2020-02-18 | 严育斌 | Fleece-flower root essence-increasing capsule |
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| CN1171970A (en) * | 1997-06-26 | 1998-02-04 | 周淑琴 | Health-care wine with antisenility function |
| CN1254566A (en) * | 1998-11-19 | 2000-05-31 | 邓道德 | Health-care food for men to build-up body, nourish kidney and invigorate Yang |
| CN1356137A (en) * | 2001-11-26 | 2002-07-03 | 张向阳 | Medical pill for nourishing kidney and promoting sperm generation |
| CN1368112A (en) * | 2001-01-31 | 2002-09-11 | 杨孟君 | Nano medicine 'Yishenling' and its preparing process |
| CN1488396A (en) * | 2003-08-29 | 2004-04-14 | 北京奥羚博大医药科技发展有限公司 | Chinese medicine for treating asynodia |
| CN101195015A (en) * | 2007-11-30 | 2008-06-11 | 黄宁芝 | Chinese medicine for treating barrenness |
-
2009
- 2009-02-15 CN CN2009100144280A patent/CN101485859B/en not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1171970A (en) * | 1997-06-26 | 1998-02-04 | 周淑琴 | Health-care wine with antisenility function |
| CN1254566A (en) * | 1998-11-19 | 2000-05-31 | 邓道德 | Health-care food for men to build-up body, nourish kidney and invigorate Yang |
| CN1368112A (en) * | 2001-01-31 | 2002-09-11 | 杨孟君 | Nano medicine 'Yishenling' and its preparing process |
| CN1356137A (en) * | 2001-11-26 | 2002-07-03 | 张向阳 | Medical pill for nourishing kidney and promoting sperm generation |
| CN1488396A (en) * | 2003-08-29 | 2004-04-14 | 北京奥羚博大医药科技发展有限公司 | Chinese medicine for treating asynodia |
| CN101195015A (en) * | 2007-11-30 | 2008-06-11 | 黄宁芝 | Chinese medicine for treating barrenness |
Non-Patent Citations (2)
| Title |
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| 卫生部.参茸固本片.《卫生部颁药品标准中药成方制剂第二十册》.1998,163. * |
| 卫生部.参茸延龄片.《卫生部颁药品标准中药成方制剂第十三册》.1997,120. * |
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| CN101485859A (en) | 2009-07-22 |
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Granted publication date: 20110907 Termination date: 20120215 |