CN102526635B - Medicament for treating premenstrual stress syndrome and preparation method thereof - Google Patents
Medicament for treating premenstrual stress syndrome and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicament for treating a premenstrual stress syndrome. The medicament is prepared from the following medicinal raw materials: Chinese thorowax root, nutgrass galingale rhizome, green tangerine peel, turmeric root-tuber, bitter orange, Chinese angelica, tree peony root-bark, red-rooted salvia root, red paeony root, silktree albizzia bark, cowherb seed, uniflower swisscentaury root, saffron, szechwan Chinaberry fruit, mulberry leaf, manyleaf paris rhizome, purpleflower holly leaf, sinkiang arnebia root, beautiful sweetgum fruit, ricepaper pith, indian buead, szechuan lovage rhizome, Chinese yam, coix seed, citron fruit, fingered citron, glossy privet fruit, eclipta herb, malaytea scurfpea fruit, cornus officinalis, peach kernel and rose. Thirty-two Chinese medicines draw on each other's strength, complete each other, and coact on liver, spleen and kidney. The medicament disclosed by the invention has the effects of soothing the liver, regulating the spleen, activating the channels, promoting blood circulation by removing blood stasis, regulating the menstrual function, tonifying the kidney, conditioning and controlling vessels. The medicament has a unique and remarkable curative effect on the premenstrual stress syndrome.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of premenstrualtension syndrome and preparation method thereof.
Background technology
Premenstrualtension syndrome is the common a kind of comprehensive syndrome of gynecological clinic, the series of symptoms before referring to periodically occur passing through.This disease is apt to occur in any age bracket of the women that passes through, can the symptoms such as irritated irritability, abdominal distention stomachache, distending pain of the breast, distending pain in the chest and hypochondrium, asthenia, edema, insomnia, transference cure after row even more early occur the last week in menstrual period or first quarter moon.This directly affects women's emotion, very easily causes mental pressure to strengthen, and has a strong impact on women's physical and mental health.
Summary of the invention
The purpose of this invention is to provide a kind of cheap, medicine for the treatment of easily premenstrualtension syndrome and preparation method thereof of drawing materials.
To achieve these goals, a kind of medicine for the treatment of premenstrualtension syndrome of the present invention, it is characterized in that: the medicine material by following parts by weight is made: Radix Bupleuri 12～30; Rhizoma Cyperi 15～30; Pericarpium Citri Reticulatae Viride 10～30; Radix Curcumae 10～30; Fructus Aurantii 12～30; Radix Angelicae Sinensis 10～40; Cortex Moutan 12～30; Radix Salviae Miltiorrhizae 12～40; Radix Paeoniae Rubra 10～30; Cortex Albiziae 10～40; Semen Vaccariae 10～40; Radix Rhapontici 10～30; Flos Carthami 10～40; Fructus Toosendan 10～40; Folium Mori 10～30; Rhizoma Paridis 10～40; Ilex purpurea Hassk.[I.chinensis Sims 15～25; Radix Arnebiae (Radix Lithospermi) 15～25; Fructus Liquidambaris 15～25; Medulla Tetrapanacis 5～25; Poria 20～30; Rhizoma Chuanxiong 10～20; Rhizoma Dioscoreae 30～60; Semen Coicis 20～50; Fructus Citri 12～30; Fructus Citri Sarcodactylis 12～30; Fructus Ligustri Lucidi 15～50; Herba Ecliptae 15～50; Fructus Psoraleae 15～50; Fructus Corni 15～50; Semen Persicae 15～30; Flos Rosae Rugosae 30～40.
Above-mentioned a kind of medicine for the treatment of premenstrualtension syndrome, it is characterized in that: the medicine material by following parts by weight is made: Radix Bupleuri 20; Rhizoma Cyperi 20; Pericarpium Citri Reticulatae Viride 15; Radix Curcumae 15; Fructus Aurantii 15; Radix Angelicae Sinensis 20; Cortex Moutan 20; Radix Salviae Miltiorrhizae 20; Radix Paeoniae Rubra 20; Cortex Albiziae 20; Semen Vaccariae 20; Radix Rhapontici 20; Flos Carthami 20; Fructus Toosendan 15; Folium Mori 20; Rhizoma Paridis 20; Ilex purpurea Hassk.[I.chinensis Sims 20; Radix Arnebiae (Radix Lithospermi) 20; Fructus Liquidambaris 20; Medulla Tetrapanacis 20; Poria 25; Rhizoma Chuanxiong 15; Rhizoma Dioscoreae 50; Semen Coicis 30; Fructus Citri 20; Fructus Citri Sarcodactylis 20; Fructus Ligustri Lucidi 40, Herba Ecliptae 40; Fructus Psoraleae 40; Fructus Corni 40; Semen Persicae 20; Flos Rosae Rugosae 30.
A kind of preparation method for the treatment of the premenstrualtension syndrome medicine is characterized in that: according to above-mentioned medicine material parts by weight, put into marmite, add approximately 800 weight portions of cold water, soaked 1 hour, after big fire was fried open, little fire was fried in shallow oil 15～20 minutes; Medicine juice is poured in ready glass container; The marmite giving drugs into nose is added cold water 300 weight portions, as above method is fried again, and the secondary rear medicine juice of boiling medicine is poured into again in glass container and mixed, and twice admixing medical solutions be 500 weight portions approximately, and admixing medical solutions 250ml is potion.
Using method is potion on the one, and serveing on 15 after menstruation is clean is a course for the treatment of.
The present invention puts into marmite with medicine, the effective ingredient that takes Radix Bupleuri, Rhizoma Cyperi, Pericarpium Citri Reticulatae Viride, Radix Curcumae, Fructus Aurantii, Radix Angelicae Sinensis, Cortex Moutan, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Cortex Albiziae, Semen Vaccariae, Radix Rhapontici, Flos Carthami, Fructus Toosendan, Folium Mori, Rhizoma Paridis, Ilex purpurea Hassk.[I.chinensis Sims, Radix Arnebiae (Radix Lithospermi), Fructus Liquidambaris, Medulla Tetrapanacis, Poria, Rhizoma Chuanxiong, Rhizoma Dioscoreae, Semen Coicis, Fructus Citri, Fructus Citri Sarcodactylis, Fructus Ligustri Lucidi, Herba Ecliptae, Fructus Psoraleae, Fructus Corni, Semen Persicae, Flos Rosae Rugosae is oral, 32 flavor Chinese medicines are learnt from other's strong points to offset one's weaknesses, complementation is held up mutually, and combined effect is in liver, spleen and kidney.This agent medicine has the smooth the liver and regulate the spleen collateral dredging, blood circulation promoting and blood stasis dispelling regulating menstruation, the effect of the kidney invigorating Chong and Ren Meridians regulating.The present invention treats premenstrualtension syndrome unique significant curative effect.
The specific embodiment
Embodiment 1:(most preferred embodiment)
A kind of medicine for the treatment of premenstrualtension syndrome of the present invention is made by the medicine material of following weight:
Radix Bupleuri 20g; Rhizoma Cyperi 20g; Pericarpium Citri Reticulatae Viride 15g; Radix Curcumae 15g; Fructus Aurantii 15g; Radix Angelicae Sinensis 20g; Cortex Moutan 20g; Radix Salviae Miltiorrhizae 20g; Radix Paeoniae Rubra 20g; Cortex Albiziae 20g; Semen Vaccariae 20g; Radix Rhapontici 20g; Flos Carthami 20g; Fructus Toosendan 15g; Folium Mori 20g; Rhizoma Paridis 20g; Ilex purpurea Hassk.[I.chinensis Sims 20g; Radix Arnebiae (Radix Lithospermi) 20g; Fructus Liquidambaris 20g; Medulla Tetrapanacis 20g; Poria 25g; Rhizoma Chuanxiong 15g; Rhizoma Dioscoreae 50g; Semen Coicis 30g; Fructus Citri 20g; Fructus Citri Sarcodactylis 20g; Fructus Ligustri Lucidi 40g, Herba Ecliptae 40g; Fructus Psoraleae 40g; Fructus Corni 40g; Semen Persicae 20g; Flos Rosae Rugosae 30g.
The present invention treats the preparation method of premenstrualtension syndrome medicine:
First Radix Bupleuri 20g will be placed in marmite; Rhizoma Cyperi 20g; Pericarpium Citri Reticulatae Viride 15g; Radix Curcumae 15g; Fructus Aurantii 15g; Radix Angelicae Sinensis 20g; Cortex Moutan 20g; Radix Salviae Miltiorrhizae 20g; Radix Paeoniae Rubra 20g; Cortex Albiziae 20g; Semen Vaccariae 20g; Radix Rhapontici 20g; Flos Carthami 20g; Fructus Toosendan 15g; Folium Mori 20g; Rhizoma Paridis 20g; Ilex purpurea Hassk.[I.chinensis Sims 20g; Radix Arnebiae (Radix Lithospermi) 20g; Fructus Liquidambaris 20g; Medulla Tetrapanacis 20g; Poria 25g; Rhizoma Chuanxiong 15g; Rhizoma Dioscoreae 50g; Semen Coicis 30g; Fructus Citri 20g; Fructus Citri Sarcodactylis 20g; Fructus Ligustri Lucidi 40g, Herba Ecliptae 40g; Fructus Psoraleae 40g; Fructus Corni 40g; Semen Persicae 20g; Flos Rosae Rugosae 30g; Add approximately 800ml of cold water, soaked 1 hour, after big fire was fried open, little fire was fried in shallow oil 15～20 minutes.Medicine juice is poured in ready glass container.Again the marmite giving drugs into nose is added cold water 300ml, as above method is fried, and the secondary rear medicine juice of boiling medicine is poured into again in glass container and mixed, and twice admixing medical solutions be 500ml approximately, and minutes 2 times oral.Potion on the one, serveing on 15 after menstruation is clean is a course for the treatment of.
The present invention puts into marmite with medicine, the effective ingredient that takes Radix Bupleuri, Rhizoma Cyperi, Pericarpium Citri Reticulatae Viride, Radix Curcumae, Fructus Aurantii, Radix Angelicae Sinensis, Cortex Moutan, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Cortex Albiziae, Semen Vaccariae, Radix Rhapontici, Flos Carthami, Fructus Toosendan, Folium Mori, Rhizoma Paridis, Ilex purpurea Hassk.[I.chinensis Sims, Radix Arnebiae (Radix Lithospermi), Fructus Liquidambaris, Medulla Tetrapanacis, Poria, Rhizoma Chuanxiong, Rhizoma Dioscoreae, Semen Coicis, Fructus Citri, Fructus Citri Sarcodactylis, Fructus Ligustri Lucidi, Herba Ecliptae, Fructus Psoraleae, Fructus Corni, Semen Persicae, Flos Rosae Rugosae is oral, 32 flavor Chinese medicines are learnt from other's strong points to offset one's weaknesses, complementation is held up mutually, and combined effect is in liver, spleen and kidney.This agent medicine has the smooth the liver and regulate the spleen collateral dredging, blood circulation promoting and blood stasis dispelling regulating menstruation, the effect of the kidney invigorating Chong and Ren Meridians regulating.The present invention treats premenstrualtension syndrome unique significant curative effect.
The side separates:
Radix Bupleuri, Rhizoma Cyperi, Pericarpium Citri Reticulatae Viride, Fructus Aurantii: soothing the liver, regulate the flow of vital energy, pain relieving.
Folium Mori, Rhizoma Paridis, Ilex purpurea Hassk.[I.chinensis Sims: heat clearing and blood circulation promoting, moisturize.
Cortex Moutan, Radix Paeoniae Rubra, Radix Arnebiae (Radix Lithospermi), Fructus Liquidambaris: clearing away heat and cooling blood, invigorate blood circulation, collateral dredging.
Poria, Rhizoma Dioscoreae, Semen Coicis: spleen invigorating, collateral dredging, regulating menstruation.
Radix Salviae Miltiorrhizae, Flos Carthami, Rhizoma Cyperi, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Medulla Tetrapanacis: invigorate blood circulation, soothing the liver regulating menstruation, collateral dredging, blood stasis dispelling.
Fructus Citri, Fructus Citri Sarcodactylis, Semen Persicae, Semen Vaccariae: invigorating spleen to remove dampness, collateral dredging regulating menstruation, blood stasis dispelling.
Fructus Ligustri Lucidi, Herba Ecliptae, Fructus Psoraleae, Fructus Corni: Bushen Tongluo.
Flos Rosae Rugosae: blood circulation promoting and blood stasis dispelling.
Radix Rhapontici: heat-clearing and toxic substances removing, detumescence and apocenosis, logical muscle arteries and veins.
Radix Curcumae: only invigorate blood circulation can, promoting QI circulation for relieving depression.
Cortex Albiziae: resolving stagnation for tranquilization, promoting blood circulation and detumescence.
Fructus Toosendan: soothing liver-QI promoting the circulation of QI to relieve pain.
Embodiment 2:
A kind of medicine for the treatment of premenstrualtension syndrome of the present invention is made by the medicine material of following weight:
Radix Bupleuri 30g; Rhizoma Cyperi 30g; Pericarpium Citri Reticulatae Viride 30g; Radix Curcumae 30g; Fructus Aurantii 30g; Radix Angelicae Sinensis 40g; Cortex Moutan 30g; Radix Salviae Miltiorrhizae 40g; Radix Paeoniae Rubra 30g; Cortex Albiziae 40g; Semen Vaccariae 40g; Radix Rhapontici 30g; Flos Carthami 40g; Fructus Toosendan 40g; Folium Mori 20g; Rhizoma Paridis 20g; Ilex purpurea Hassk.[I.chinensis Sims 20g; Radix Arnebiae (Radix Lithospermi) 20g; Fructus Liquidambaris 20g; Medulla Tetrapanacis 20g; Poria 25g; Rhizoma Chuanxiong 15g; Rhizoma Dioscoreae 50g; Semen Coicis 30g; Fructus Citri 20g; Fructus Citri Sarcodactylis 20g; Fructus Ligustri Lucidi 40g, Herba Ecliptae 40g; Fructus Psoraleae 40g; Fructus Corni 40g; Semen Persicae 20g; Flos Rosae Rugosae 40g.
Preparation method is with embodiment 1.
The present embodiment Chinese herbal medicine dosage is excessive, and stomach discomfort after general patient's oral drugs has symptom of diarrhea.
Embodiment 3:
A kind of medicine for the treatment of premenstrualtension syndrome of the present invention is made by the medicine material of following weight:
Radix Bupleuri 12g; Rhizoma Cyperi 15g; Pericarpium Citri Reticulatae Viride 12g; Radix Curcumae 15g; Fructus Aurantii 12g; Radix Angelicae Sinensis 10g; Cortex Moutan 12g; Radix Salviae Miltiorrhizae 12g; Radix Paeoniae Rubra 10g; Cortex Albiziae 10g; Semen Vaccariae 10g; Radix Rhapontici 10g; Flos Carthami 10g; Fructus Toosendan 10g; Folium Mori 10g; Rhizoma Paridis 10g; Ilex purpurea Hassk.[I.chinensis Sims 15g; Radix Arnebiae (Radix Lithospermi) 15g; Fructus Liquidambaris 15g; Medulla Tetrapanacis 10g; Poria 20g; Rhizoma Chuanxiong 10g; Rhizoma Dioscoreae 30g; Semen Coicis 20g; Fructus Citri 15g; Fructus Citri Sarcodactylis 15g; Fructus Ligustri Lucidi 20g, Herba Ecliptae 20g; Fructus Psoraleae 20g; Fructus Corni 20g; Semen Persicae 15g; Flos Rosae Rugosae 30 g.
Preparation method is with embodiment 1.
The present embodiment Chinese herbal medicine dosage is less, and the course for the treatment of is longer, and effect is relatively poor.
Embodiment 4:
A kind of medicine for the treatment of premenstrualtension syndrome of the present invention is made by the medicine material of following weight:
Radix Bupleuri 20g; Rhizoma Cyperi 20g; Pericarpium Citri Reticulatae Viride 20g; Radix Curcumae 15g; Fructus Aurantii 15g; Radix Angelicae Sinensis 20g; Cortex Moutan 20g; Radix Salviae Miltiorrhizae 25g; Radix Paeoniae Rubra 25g; Cortex Albiziae 20g; Semen Vaccariae 20g; Radix Rhapontici 20g; Flos Carthami 20g; Fructus Toosendan 15g; Folium Mori 20g; Rhizoma Paridis 25g; Ilex purpurea Hassk.[I.chinensis Sims 25g; Radix Arnebiae (Radix Lithospermi) 20g; Fructus Liquidambaris 20g; Medulla Tetrapanacis 20g; Poria 25g; Rhizoma Chuanxiong 15g; Rhizoma Dioscoreae 40g; Semen Coicis 30g; Fructus Citri 20g; Fructus Citri Sarcodactylis 20g; Fructus Ligustri Lucidi 35g, Herba Ecliptae 35g; Fructus Psoraleae 35g; Fructus Corni 35g; Semen Persicae 20g; Flos Rosae Rugosae 35g.
Preparation method is with embodiment 1.
The present embodiment dosage is relatively moderate, but mouthfeel is more bitter, and effect is not as embodiment 1.
Embodiment 1 pharmacodynamic experiment report:
Physical data:
Get outpatient service 200 examples, divide at random treatment group and matched group.Treatment group 100 examples, at minimum 22 years old of age, maximum 47 years old, the course of disease was the shortest 3 months, elder 6 years.Workman's 40 examples, peasant's 42 examples, cadre's 18 examples.
Matched group 100 examples, minimum 25 years old of age, the maximum 45 years old.The course of disease is the shortest 6 months, elder 4 years.Workman's 42 examples, peasant's 44 examples, cadre's 14 examples.
Two groups of ages, occupation, course of disease situations compare, and two groups of data are learned processing (P＞0.05) by statistics, and no significant difference has comparability.
Diagnostic criteria:
1, premenstrualtension syndrome can betide any age bracket of the women that passes through.
2, can the symptoms such as irritated irritability, abdominal distention stomachache, distending pain of the breast, distending pain in the chest and hypochondrium, asthenia, edema, insomnia, transference cure after row even more early appear the last week in menstrual period or first quarter moon.
3, this directly affects women's emotion, very easily causes mental pressure to strengthen, and has a strong impact on women's physical and mental health.
Therapeutic Method: treatment group is taken course for the treatment of of the present invention, observe the curative effect, the oral rhizoma corydalis pain relieving soft capsules of matched group (the accurate word Z20063013 of traditional Chinese medicines), composition has Rhizoma Corydalis (vinegar system), the Radix Angelicae Dahuricae etc., 4-6 time on the one, one time 3,15 is a course for the treatment of, one the course for the treatment of observe the curative effect.
Therapeutic outcome:
Two groups of premenstrualtension syndrome patients observe through a course of therapy, the results are shown in Table:
Table 1 liang group curative effect is than effect
Annotate: compare with matched group, difference is very significant (χ
2=67.60, P＜0.01).
Use the present invention and treat premenstrualtension syndrome 100 examples, through 1 course of therapy, cure 78 examples, 20 examples that take a turn for the better, invalid 2 examples, cure rate 78%, total effective rate 98% is learned by statistics and is processed (χ
2Check), the treatment group curative effect is apparently higher than matched group (P＜0.01).
Observe through treating 2 courses for the treatment of, the results are shown in Table 2.
Table 2 liang group curative effect relatively
Annotate: compare with matched group, difference is very significant (χ
2=77.61, P＜0.01).
Observe through the 2nd course of therapy, treatment group is always cured 94 examples, 4 examples that take a turn for the better, and cure rate 94%, total effective rate 98% is learned by statistics and is processed (χ
2Check), the treatment group curative effect is apparently higher than matched group (P＜0.01).
The present invention treats the analysis of premenstrualtension syndrome clinical practice social benefit:
Premenstrualtension syndrome is the common a kind of comprehensive syndrome of gynecological clinic, the series of symptoms before referring to periodically occur passing through.This disease is apt to occur in any age bracket of the women that passes through, can the symptoms such as irritated irritability, abdominal distention stomachache, distending pain of the breast, distending pain in the chest and hypochondrium, asthenia, edema, insomnia, transference cure after row even more early occur the last week in menstrual period or first quarter moon.This directly affects women's emotion, very easily causes mental pressure to strengthen, and has a strong impact on women's physical and mental health.Therefore, research treatment premenstrualtension syndrome has efficiently, safely, the prescription preparation that has no side effect, painful to remove the women, satisfying the clinical treatment demand has very important meaning.
The present invention is on the basis of clinical treatment experience for many years, in conjunction with latest modern technological pharmacological research achievement, repeatedly confirms through clinical, formulation science, effect is remarkable, has no side effect, not only the smooth the liver and regulate the spleen collateral dredging, the blood circulation promoting and blood stasis dispelling regulating menstruation, the effects such as the kidney invigorating Chong and Ren Meridians regulating, and practical value is high, cheap, draw materials conveniently, simple for production.
Use the present invention and treat premenstrualtension syndrome patient 212 examples, minimum 22 years old of age, the maximum 47 years old, and 212 routine patients are carried out follow-up investigation, and clinical cure 167 examples, cure rate reaches 78.8%, effective 41 examples, invalid 4 examples, total effective rate reaches 98.1%.The patient with slight symptoms takes effect after taking a week, and the patient with severe symptoms serve on 3 courses for the treatment of, follows up a case by regular visits to the present invention without any untoward reaction in individual month through 6-10, and premenstrualtension syndrome is had significant curative effect, and is safe and reliable.
Model case:
Case one: the king * *, the female, 45 years old, through front irritated 5 years, irritated irritability, distending pain of the breast, abdominal distention hypochondriac pain appearred in the patient at every turn through the last week, and through spontaneous remission of row, menstrual period are still accurate, but Hypomenorrhea, color is dark, companion's clot, red tip of the tongue white and thin fur, stringy pulse.Card belongs to stagnation of QI due to depression of the liver, Chong and Ren channel disorder.Control with depressed liver-energy dispersing and QI regulating, promoting blood flow to regulate menstruation, Bushen Tiaochong is appointed.Take 1 course for the treatment of of the present invention, above-mentioned all cards alleviate, and the symptom major parts such as fidgety irritability disappear, and continue again to take 2 courses for the treatment of of the present invention, and menstruation is also normal, and premenstrualtension syndrome disappears fully.
Case two: old * *, the female, 23 years old, more than premenstrualtension syndrome March.Body is thin and weak, and the dysmenorrhea history is arranged.Now through after 2 days, lower abdomen dull pain ， Yao Acid, weak, hectic fever, irritated irritability, distending pain of the breast, distending pain in the chest and hypochondrium, insomnia thin white fur of tongue, thready pulse.Card belongs to the deficiency of the kidney yin blood stasis.Control with blood stasis dispelling, regulating menstruation, Bushen Tiaochong is appointed.After taking the present invention 1 course for the treatment of, premenstrualtension syndrome disappears.
Case three: Zhao * *, female, 28 years old, premenstrualtension syndrome half a year.Patient post-abortion before half a year, premenstrualtension syndrome occurs.Existing menstruation rule, thin white fur of tongue, stringy pulse.After taking the present invention 1 course for the treatment of, premenstrualtension syndrome alleviates, continues again and takes one week of the present invention, and premenstrualtension syndrome disappears.
Claims (3)
1. medicine for the treatment of premenstrualtension syndrome, it is characterized in that: the medicine material by following parts by weight is made: Radix Bupleuri 12～30; Rhizoma Cyperi 15～30; Pericarpium Citri Reticulatae Viride 10～30; Radix Curcumae 10～30; Fructus Aurantii 12～30; Radix Angelicae Sinensis 10～40; Cortex Moutan 12～30; Radix Salviae Miltiorrhizae 12～40; Radix Paeoniae Rubra 10～30; Cortex Albiziae 10～40; Semen Vaccariae 10～40; Radix Rhapontici 10～30; Flos Carthami 10～40; Fructus Toosendan 10～40; Folium Mori 10～30; Rhizoma Paridis 10～40; Ilex purpurea Hassk.[I.chinensis Sims 15～25; Radix Arnebiae (Radix Lithospermi) 15～25; Fructus Liquidambaris 15～25; Medulla Tetrapanacis 5～25; Poria 20～30; Rhizoma Chuanxiong 10～20; Rhizoma Dioscoreae 30～60; Semen Coicis 20～50; Fructus Citri 12～30; Fructus Citri Sarcodactylis 12～30; Fructus Ligustri Lucidi 15～50; Herba Ecliptae 15～50; Fructus Psoraleae 15～50; Fructus Corni 15～50; Semen Persicae 15～30; Flos Rosae Rugosae 30～40.
2. a kind of medicine for the treatment of premenstrualtension syndrome according to claim 1, it is characterized in that: the medicine material by following parts by weight is made: Radix Bupleuri 20; Rhizoma Cyperi 20; Pericarpium Citri Reticulatae Viride 15; Radix Curcumae 15; Fructus Aurantii 15; Radix Angelicae Sinensis 20; Cortex Moutan 20; Radix Salviae Miltiorrhizae 20; Radix Paeoniae Rubra 20; Cortex Albiziae 20; Semen Vaccariae 20; Radix Rhapontici 20; Flos Carthami 20; Fructus Toosendan 15; Folium Mori 20; Rhizoma Paridis 20; Ilex purpurea Hassk.[I.chinensis Sims 20; Radix Arnebiae (Radix Lithospermi) 20; Fructus Liquidambaris 20; Medulla Tetrapanacis 20; Poria 25; Rhizoma Chuanxiong 15; Rhizoma Dioscoreae 50; Semen Coicis 30; Fructus Citri 20; Fructus Citri Sarcodactylis 20; Fructus Ligustri Lucidi 40, Herba Ecliptae 40; Fructus Psoraleae 40; Fructus Corni 40; Semen Persicae 20; Flos Rosae Rugosae 30.
3. the preparation method of the medicine of the described treatment premenstrualtension syndrome of claim 1 or 2, is characterized in that: according to described medicine material parts by weight, put into marmite, add approximately 800 weight portions of cold water, soaked 1 hour, after big fire was fried open, little fire was fried in shallow oil 15～20 minutes; Medicine juice is poured in ready glass container; The marmite giving drugs into nose is added cold water 300 weight portions, as above method is fried again, and the secondary rear medicine juice of boiling medicine is poured into again in glass container and mixed, and twice admixing medical solutions be 500 weight portions approximately, and admixing medical solutions 250ml is potion.
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| CN103446567B (en) * | 2013-08-30 | 2015-04-29 | 翔宇药业股份有限公司 | Premenstrual ease pharmaceutical composition and preparation technique thereof |
| CN103638508B (en) * | 2013-12-03 | 2016-08-17 | 徐承香 | The Chinese medicine for the treatment of premenstrualtension syndrome |
| CN104352988B (en) * | 2014-11-21 | 2017-09-08 | 漯河医学高等专科学校 | A kind of Chinese medicine for treating premenstrual tension syndrome |
| CN104740578B (en) * | 2015-04-12 | 2018-04-06 | 翔宇药业股份有限公司 | Premenstrual peace piece preparation technology and its detection method |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1220163A (en) * | 1998-11-12 | 1999-06-23 | 东莞市亚洲制药有限公司 | Drug for curing premenstrual tension |
| CN1449778A (en) * | 2002-04-09 | 2003-10-22 | 深圳太太药业有限公司 | Traditional Chinese medicine composition with function of treating dysmenorrhea and beautifying |
| CN1682989A (en) * | 2005-02-21 | 2005-10-19 | 李有田 | Chinese medicine for treating depression |
| CN101306188A (en) * | 2008-04-22 | 2008-11-19 | 梁进 | Paste for regulating menstruation and absorbing clots |
| CN101559204A (en) * | 2009-05-22 | 2009-10-21 | 邓丽菊 | Traditional Chinese medicine compound treating irregular menstruation and dysmenorrheal and application thereof in preparing hygienic products of women |
-
2012
- 2012-03-06 CN CN 201210056665 patent/CN102526635B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1220163A (en) * | 1998-11-12 | 1999-06-23 | 东莞市亚洲制药有限公司 | Drug for curing premenstrual tension |
| CN1449778A (en) * | 2002-04-09 | 2003-10-22 | 深圳太太药业有限公司 | Traditional Chinese medicine composition with function of treating dysmenorrhea and beautifying |
| CN1682989A (en) * | 2005-02-21 | 2005-10-19 | 李有田 | Chinese medicine for treating depression |
| CN101306188A (en) * | 2008-04-22 | 2008-11-19 | 梁进 | Paste for regulating menstruation and absorbing clots |
| CN101559204A (en) * | 2009-05-22 | 2009-10-21 | 邓丽菊 | Traditional Chinese medicine compound treating irregular menstruation and dysmenorrheal and application thereof in preparing hygienic products of women |
Non-Patent Citations (6)
| Title |
|---|
| 中医辨证治疗经前期紧张综合征;高华;《河南中医学院学报》;20050220(第01期);全文 * |
| 刘建等.经前期综合征的中医辨证论治探讨.《辽宁中医杂志》.2011,(第10期),全文. |
| 崔丽锐.浅谈经前期紧张综合征的中医药治疗.《中国民族民间医药》.2011,(第19期),全文. |
| 浅谈经前期紧张综合征的中医药治疗;崔丽锐;《中国民族民间医药》;20111015(第19期);全文 * |
| 经前期综合征的中医辨证论治探讨;刘建等;《辽宁中医杂志》;20111031(第10期);全文 * |
| 高华.中医辨证治疗经前期紧张综合征.《河南中医学院学报》.2005,(第01期),全文. |
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