CN104623330A - Chinese medicinal composition for treating hyperlipidemia - Google Patents
Chinese medicinal composition for treating hyperlipidemia Download PDFInfo
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Abstract
The invention relates to a Chinese medicinal composition for treating hyperlipidemia. The Chinese medicinal composition is prepared from the following medicinal raw materials in parts by weight: 10-40 parts of common selfheal fruits or spikes, 5-20 parts of chrysanthemums, 10-30 parts of uncaria rhynchophylla, 5-20 parts of tall gastrodia tubers, 10-40 parts of sea-ear shells, 5-20 parts of peach seeds, 10-40 parts of white peony roots, 5-25 parts of cassia seeds, 10-30 parts of processed tuber fleeceflower roots, 5-25 parts of eucommia barks, 10-40 parts of hawthorn fruits, 5-20 parts of safflowers, 10-40 parts of Danshen roots, 5-25 parts of oriental waterplantain rhizomes, 10-30 parts of Szechuan lovage rhizomes, 5-20 parts of medicinal cyathula roots, 10-40 parts of Chinese taxillus twigs, 5-20 parts of lobed kudzuvine roots, 10-30 parts of poria cocos and 5-15 parts of liquorice roots. The Chinese medicinal composition provided by the invention has the efficacies of nourishing the liver and the kidney, invigorating the spleen, supplementing qi, clearing away heat, resolving phlegm, promoting the circulation of blood and removing blood stasis, can inhibit the absorption of cholesterol, regulate the metabolism of blood lipid and promote the excretion of cholesterol, has a significant effect of treating hyperlipidemia and is reliable in function.
Description
Technical field
The present invention relates to a kind of pharmaceutical product not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of hyperlipidemia.
Background technology
Hyperlipidemia refers to that lipid metabolism or running make one or more lipids of blood plasma higher than normal value extremely, it is a kind of systemic disease, refer to blood cholesterol (TC) and/or triglyceride (TG) is too high or HDL-C (HDL-C) is too low, modern medicine is referred to as dyslipidemia.Hyperlipidemia main manifestations is obesity, and heavy sensation of the body is weak, addicted to food delicious food savoury, dizzy nose heave, gastral cavity painful abdominal mass uncomfortable in chest, indigestion and loss of appetite abdominal distention, nausea of feeling sick, and little sleep disturbed by dreams is forgetful, seminal emission night sweat, the puckery xerostomia of order, light red tongue thick and greasy fur, stringy and rolling pulse or puckery heavy.Hyperlipidemia is commonly encountered diseases, the frequently-occurring disease of person in middle and old age's metabolic disease, is the principal element causing coronary heart disease, arteriosclerosis, cerebral thrombosis and cerebral hemorrhage.In recent years due to high caloric diet, activity reduced in addition, and hyperlipidemia is tending towards rejuvenation, threatens the health of people, causes common concern.At present, the types of drugs of blood fat reducing is various, is mainly divided into Chinese medicine and the large class of Western medicine two.Western medicine side effect is large, and the lipid lowerers as Statins and Bei Te class all likely causes myositis or brain soldier.Chinese medicine blood fat reducing class types of drugs is many, but ubiquity drug ingredient is mixed, and needs to soak in manufacturing process, boil, extracts, filters, concentrated or add adjuvant, and making shortage is supervised, and causes quality unreliable.
Chinese medicine is thought hyperlipidemia is deficiency in origin and excess in superficiality, belong to blood stasis, the turbid category of expectorant, its disease is at blood, and send out in taste, root is in kidney.Clinical syndrome differentiation is attributed to that caused by liver and kidney deficiency, insufficiency of the spleen expectorant are turbid, qi depression to blood stasis more.
According to theory of Chinese medical science, for the pathogeny of hyperlipidemia, adopt the method for the treatment of of nourishing the liver and kidney, invigorating the spleen and benefiting QI, removing heat-phlegm, blood circulation promoting and blood stasis dispelling, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
In order to overcome in prior art the deficiency for the treatment of hyperlipidemia and existing, the invention provides a kind of prepare easy, cost is low, evident in efficacy, the Chinese medicine composition for the treatment of hyperlipidemia that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of hyperlipidemia, it is characterized in that: its raw material of Chinese medicine and weight are: Spica Prunellae 10-40 part, Flos Chrysanthemi 5-20 part, Ramulus Uncariae Cum Uncis 10-30 part, Rhizoma Gastrodiae 5-20 part, Concha Haliotidis 10-40 part, Semen Persicae 5-20 part, Radix Paeoniae Alba 10-40 part, Semen Cassiae 5-25 part, Radix Polygoni Multiflori Preparata 10-30 part, Cortex Eucommiae 5-25 part, Fructus Crataegi 10-40 part, Flos Carthami 5-20 part, Radix Salviae Miltiorrhizae 10-40 part, Rhizoma Alismatis 5-25 part, Rhizoma Chuanxiong 10-30 part, Radix Cyathulae 5-20 part, Herba Taxilli 10-40 part, Radix Puerariae 5-25 part, Poria 10-30 part, Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of hyperlipidemia, is characterized in that: its raw material of Chinese medicine and weight are: Spica Prunellae 30 parts, Flos Chrysanthemi 10 parts, Ramulus Uncariae Cum Uncis 20 parts, 10 parts, Rhizoma Gastrodiae, Concha Haliotidis 30 parts, 10 parts, Semen Persicae, the Radix Paeoniae Alba 30 parts, Semen Cassiae 15 parts, Radix Polygoni Multiflori Preparata 20 parts, the Cortex Eucommiae 15 parts, Fructus Crataegi 30 parts, 10 parts, Flos Carthami, Radix Salviae Miltiorrhizae 30 parts, Rhizoma Alismatis 15 parts, Rhizoma Chuanxiong 20 parts, Radix Cyathulae 10 parts, Herba Taxilli 30 parts, Radix Puerariae 15 parts, Poria 20 parts, 10 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: Spica Prunellae has effect of liver heat removing and eyesight improving, clearing away heat and promoting diuresis, mass dissipating and swelling eliminating; Flos Chrysanthemi has effect of dispelling wind and heat pathogens, suppressing the hyperactive liver improving eyesight, heat-clearing and toxic substances removing; Ramulus Uncariae Cum Uncis has effect of heat clearing away suppressing the hyperactive liver, relieving spasm by subduing liver-wind; Rhizoma Gastrodiae has effect of relieving spasm by subduing liver-wind, suppressing the hyperactive liver and subsiding YANG, dispelling wind and removing obstruction in the collateral; Concha Haliotidis has effect of suppressing the hyperactive liver and subsiding YANG, liver heat removing and eyesight improving; Semen Persicae has effect of blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation; The Radix Paeoniae Alba has effect of nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant; Semen Cassiae has effect of clearing away heat to improve acuity of vision, loosening bowel to relieve constipation; Radix Polygoni Multiflori Preparata has effect of invigorating the liver and kidney, benefiting essence-blood, black beard and hair, bone and muscle strengthening; The Cortex Eucommiae has effect of invigorating the liver and kidney, bone and muscle strengthening, invigorating middle warmer benefit vital essence; Fructus Crataegi has effect of promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis, phlegm reduction of blood circulation promoting; Flos Carthami has effect of promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain; Radix Salviae Miltiorrhizae has effect of promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; Rhizoma Alismatis has promoting diuresis to eliminate damp pathogen, expel the heat-evil treating stranguria effect; Rhizoma Chuanxiong has effect of blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping; Radix Cyathulae has effect of promoting blood circulation to restore menstrual flow, expelling wind and removing dampness, easing joint movement, inducing diuresis for treating stranguria syndrome; Herba Taxilli has effect of invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit; Radix Puerariae has relieving muscles diaphoresis, invigorating YANG QI to promote eruption, antipyretic effect of promoting the production of body fluid; Poria has benefiting vital QI for tranquillizing, invigorating the spleen and regulating the stomach, dispels effect that is damp and hot, row water stopping leak; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component is through dialectical compatibility, help using mutually assistant, play effect of nourishing the liver and kidney, invigorating the spleen and benefiting QI, removing heat-phlegm, blood circulation promoting and blood stasis dispelling altogether, thus suppress the absorption of cholesterol, adjusting blood lipid metabolism, promote Cholesterol Excretion, treating both the principal and secondary aspects of a disease is reached to the treatment of hyperlipidemia.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts the use that is decocted in water for oral dose.Through clinical practice checking, it is reliably evident in efficacy, mild in medicine property and, do not occur toxic and side effects, effective percentage reaches 92%, cure rate 63%.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for hyperlipidemia, its raw material of Chinese medicine and weight proportion are: Spica Prunellae 30g, Flos Chrysanthemi 10g, Ramulus Uncariae Cum Uncis 20g, Rhizoma Gastrodiae 10g, Concha Haliotidis 30g, Semen Persicae 10g, Radix Paeoniae Alba 30g, Semen Cassiae 15g, Radix Polygoni Multiflori Preparata 20g, Cortex Eucommiae 15g, Fructus Crataegi 30g, Flos Carthami 10g, Radix Salviae Miltiorrhizae 30 parts, Rhizoma Alismatis 15g, Rhizoma Chuanxiong 20g, Radix Cyathulae 10g, Herba Taxilli 30g, Radix Puerariae 15g, Poria 20g, Radix Glycyrrhizae 10g.
Embodiment 2
Treat a Chinese medicine composition for hyperlipidemia, its raw material of Chinese medicine and weight proportion are: Spica Prunellae 15g, Flos Chrysanthemi 20g, Ramulus Uncariae Cum Uncis 10g, Rhizoma Gastrodiae 20g, Concha Haliotidis 10g, Semen Persicae 20g, Radix Paeoniae Alba 10g, Semen Cassiae 25g, Radix Polygoni Multiflori Preparata 15g, Cortex Eucommiae 20g, Fructus Crataegi 10g, Flos Carthami 20g, Radix Salviae Miltiorrhizae 15 parts, Rhizoma Alismatis 25g, Rhizoma Chuanxiong 10g, Radix Cyathulae 20g, Herba Taxilli 15g, Radix Puerariae 25g, Poria 10g, Radix Glycyrrhizae 12g.
Embodiment 3
Treat a Chinese medicine composition for hyperlipidemia, its raw material of Chinese medicine and weight proportion are: Spica Prunellae 25g, Flos Chrysanthemi 12g, Ramulus Uncariae Cum Uncis 15g, Rhizoma Gastrodiae 12g, Concha Haliotidis 20g, Semen Persicae 12g, Radix Paeoniae Alba 40g, Semen Cassiae 5g, Radix Polygoni Multiflori Preparata 25g, Cortex Eucommiae 10g, Fructus Crataegi 40g, Flos Carthami 12g, Radix Salviae Miltiorrhizae 25 parts, Rhizoma Alismatis 10g, Rhizoma Chuanxiong 25g, Radix Cyathulae 15g, Herba Taxilli 10g, Radix Puerariae 20g, Poria 15g, Radix Glycyrrhizae 8g.
Embodiment 4
Treat a Chinese medicine composition for hyperlipidemia, its raw material of Chinese medicine and weight proportion are: Spica Prunellae 10g, Flos Chrysanthemi 15g, Ramulus Uncariae Cum Uncis 25g, Rhizoma Gastrodiae 5g, Concha Haliotidis 25g, Semen Persicae 15g, Radix Paeoniae Alba 20g, Semen Cassiae 10g, Radix Polygoni Multiflori Preparata 30g, Cortex Eucommiae 5g, Fructus Crataegi 25g, Flos Carthami 5g, Radix Salviae Miltiorrhizae 10 parts, Rhizoma Alismatis 20g, Rhizoma Chuanxiong 15g, Radix Cyathulae 5g, Herba Taxilli 25g, Radix Puerariae 10g, Poria 25g, Radix Glycyrrhizae 5g.
Embodiment 5
Treat a Chinese medicine composition for hyperlipidemia, its raw material of Chinese medicine and weight proportion are: Spica Prunellae 40g, Flos Chrysanthemi 5g, Ramulus Uncariae Cum Uncis 30g, Rhizoma Gastrodiae 15g, Concha Haliotidis 40g, Semen Persicae 5g, Radix Paeoniae Alba 35g, Semen Cassiae 20g, Radix Polygoni Multiflori Preparata 10g, Cortex Eucommiae 25g, Fructus Crataegi 10g, Flos Carthami 15g, Radix Salviae Miltiorrhizae 40 parts, Rhizoma Alismatis 5g, Rhizoma Chuanxiong 30g, Radix Cyathulae 12g, Herba Taxilli 40g, Radix Puerariae 5g, Poria 30g, Radix Glycyrrhizae 15g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and covers powder, soaks 15 ~ 20 minutes, then adds water and do not have powder about 6 centimetres, carries out first time to decoct, and adopts intense fire to decoct, with slow fire boiling 20 ~ 30 minutes after boiling at a simmer; Second time decocts, and adds water and does not have powder about 4 centimetres, decocts 15 ~ 20 minutes after water boils.Decoct extracting juice twice, merge.
The present invention, with a kind of Chinese medicine composition for the treatment of hyperlipidemia given by embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation case 100 example, man 54 example, female 46 example, 20 ~ 70 years old age.
Two, diagnosis basis:
(1) Western medicine diagnose standard: in normal diet situation, 2 weeks interior survey for 2 times serum total cholesterol (TC) all >=6.0mmol/L (230mg/dL), or triglyceride (TG) >=1.54mmol/L (140mg/dL), or HDL-C (HDL-C) man≤1.04mmol/L (40mg/dL), female≤1.17mmol/L (45mg/dL) person.
(2) Standards of Chinese Medical Syndrome Differentiation: dizzy, headache, uncomfortable in chest, face purple lip is dark, spiritlessness and weakness, extremities being not warm, distension and fullness in the abdomen, indigestion and loss of appetite loose stool, soreness of the waist and knees, dimly red tongue or purple dark or have petechia ecchymosis or have that tooth prints, Tai Bai or greasy in vain, deep-thready pulse or heavy.
Three, usage and dosage: during clinical practice, potion on the one, decocting twice extracting juice is about 400ml, point morning, late twice empty stomach decoction being taken warmly.It within six days, is a course for the treatment of.Treatments period is avoided cold and uncooked food the thing of pungent stimulation.
Four, criterion of therapeutical effect:
(1) cure: clinical symptoms, sign disappear, the every inspection of laboratory recovers normal;
(2) effective: clinical symptoms, sign disappear substantially, lipids detection reaches following any one person: TC declines >=20%, TG decline >=40%, HDL-C rising >=0.26mmol/L (10mg/dL), TC-HDL-C/HDL-C decline >=20%;
(3) effective: clinical symptoms, sign all take a favorable turn, lipids detection reaches following any one person: TC declines >=10% but < 20%, TG declines >=20% but < 40%, HDL-C rising 0.104mmol/L (4mg/dL) but < 0.26mmol/L (10mg/dL), TC-HDL-C/HDL-C decline >=10% but < 20%;
(4) invalid: symptom, sign and the lipids detection person of being not improved after treatment.
Five, therapeutic effect: in this clinical observation case, takes medicine 2-5 the course for the treatment of, and recovery from illness 63 example, follows up a case by regular visits to and have no recurrence; Effective 20 examples, effective 9 examples, invalid 8 examples.There is not toxic and side effects in treatments period.
Six, model case:
Case 1:
Beam, female, 37 years old.Dizziness, headache, uncomfortable in chest, distension and fullness in the abdomen, spiritlessness and weakness was started before half a year.On inspection, serum total cholesterol (TC) 9.7mmol/L, triglyceride (TG) 3.35mmol/L.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, the symptoms such as dizziness, headache obviously alleviate; Continue to take 2 courses for the treatment of, all transference cures, serum total cholesterol (TC) 5.6mmol/L, triglyceride (TG) 1.05mmol/L, recovery from illness.Follow up a case by regular visits to after half a year without recurrence.
Case 2:
Bring up certain, man, 52 years old.Over one year, often dizzy, uncomfortable in chest, breathe hard, soreness of the waist and knees, asthenia.Examine and see: dimly red tongue has ecchymosis, deep and hesitant pulse.On inspection, serum total cholesterol (TC) 8.6mmol/L, triglyceride (TG) 3.3mmol/L.Take 3 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, the symptom such as dizzy, uncomfortable in chest is eased; Continue to take 2 courses for the treatment of, serum total cholesterol (TC) 5.5mmol/L, triglyceride (TG) 1.25mmol/L, recovery from illness.
Claims (2)
1. treat a Chinese medicine composition for hyperlipidemia, it is characterized in that: its raw material of Chinese medicine and weight are: Spica Prunellae 10-40 part, Flos Chrysanthemi 5-20 part, Ramulus Uncariae Cum Uncis 10-30 part, Rhizoma Gastrodiae 5-20 part, Concha Haliotidis 10-40 part, Semen Persicae 5-20 part, Radix Paeoniae Alba 10-40 part, Semen Cassiae 5-25 part, Radix Polygoni Multiflori Preparata 10-30 part, Cortex Eucommiae 5-25 part, Fructus Crataegi 10-40 part, Flos Carthami 5-20 part, Radix Salviae Miltiorrhizae 10-40 part, Rhizoma Alismatis 5-25 part, Rhizoma Chuanxiong 10-30 part, Radix Cyathulae 5-20 part, Herba Taxilli 10-40 part, Radix Puerariae 5-25 part, Poria 10-30 part, Radix Glycyrrhizae 5-15 part.
2. a kind of Chinese medicine composition for the treatment of hyperlipidemia according to claim 1, is characterized in that: its raw material of Chinese medicine and weight are: Spica Prunellae 30 parts, Flos Chrysanthemi 10 parts, Ramulus Uncariae Cum Uncis 20 parts, 10 parts, Rhizoma Gastrodiae, Concha Haliotidis 30 parts, 10 parts, Semen Persicae, the Radix Paeoniae Alba 30 parts, Semen Cassiae 15 parts, Radix Polygoni Multiflori Preparata 20 parts, the Cortex Eucommiae 15 parts, Fructus Crataegi 30 parts, 10 parts, Flos Carthami, Radix Salviae Miltiorrhizae 30 parts, Rhizoma Alismatis 15 parts, Rhizoma Chuanxiong 20 parts, Radix Cyathulae 10 parts, Herba Taxilli 30 parts, Radix Puerariae 15 parts, Poria 20 parts, 10 parts, Radix Glycyrrhizae.
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| CN105999043A (en) * | 2016-07-23 | 2016-10-12 | 孙茂志 | Traditional Chinese medicine composition for treating hyperlipidemia |
| CN112168925A (en) * | 2019-07-05 | 2021-01-05 | 黄胜昔 | Traditional Chinese medicine for reducing blood pressure and improving blood viscosity and production method thereof |
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| KR20080004158A (en) * | 2006-07-05 | 2008-01-09 | 박영준 | Composition for the prevention and treatment of hyperlipidemia and arteriosclerosis containing lower lobe extract or herbal extract |
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| CN112168925A (en) * | 2019-07-05 | 2021-01-05 | 黄胜昔 | Traditional Chinese medicine for reducing blood pressure and improving blood viscosity and production method thereof |
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