CN103142754A - Traditional Chinese medicine for treating kidney deficiency - Google Patents

Traditional Chinese medicine for treating kidney deficiency Download PDF

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CN103142754A
CN103142754A CN2013100971241A CN201310097124A CN103142754A CN 103142754 A CN103142754 A CN 103142754A CN 2013100971241 A CN2013100971241 A CN 2013100971241A CN 201310097124 A CN201310097124 A CN 201310097124A CN 103142754 A CN103142754 A CN 103142754A
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kidney
deficiency
yang
yin
chinese medicine
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吕子旺
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Abstract

The invention discloses a traditional Chinese medicine for treating kidney deficiency, namely Yin and Yang kidney-tonifying pill prepared from the following Chinese medicinal herbs by weight: 58g of angelica, 58g of ligusticum wallichii, 30g of rosa laevigata michx, 58g of eucommia, 30g of licorice, 58g of poria cocos, 30g of epimedium and 118g of radix rehmanniae preparata. The pill is prepared from the eight Chinese medicinal herbs (by an accurate weight ratio) undergoing measures of decoction, concentration, high temperature sterilization, mildew resistance and corrosion resistance and the like. The traditional Chinese medicine Yin and Yang kidney-tonifying pill disclosed by the invention has efficacies of ascending up spleen-qi and Yang, nourishing yin and tonifying yang, conditioning viscera and producing sperm and filling marrow, and after more than 50 years of a clinical verification process, the curative effect of the pill is superior to those of products for treating the kidney deficiency disease (deficiency of kidney-yin or deficiency of kidney-yang) in the current market, and has the advantages of simplicity, convenience, low cost, strong curative effect and the like.

Description

The Chinese medicine that a kind for the treatment of is suffered from a deficiency of the kidney
Technical field
The invention discloses medicine and preparation method that a kind for the treatment of is suffered from a deficiency of the kidney, specifically the Chinese medicine preparation of preparation take Chinese medicine as raw material, belong to the field of Chinese medicines.
Background technology
Chinese medicine thinks that kidney storing essence is the congenital foundation.Kidney master growth, growth and reproduction, main bone are given birth to marrow and are led in brain, and brain is the place of marrow and gods high concentration, and all thinking activitiess of people are all arranged by brain." interior warp " said: " the living marrow of kidney is discontented ".The essence of kidney is the source of people's life activity, the base substance that consists of human body, essence energy activating QI, gas energy spermatogenesis, kidney spermatogenesis, smart hemopoietic, oligospermia be disease, essence is died to the greatest extent, the essence gas that declines is weak, and smart sufficient gas is strong, weakness of QI also a little less than, arrogant blood is prosperous, qi being the governor of blood, blood being the material foundation of QI, visible essence, gas, blood are mutual dependence for existencies.Cloudy essence is that yang-energy is basic.Yang transforming qi, yin shaping up body, the moon are skillful in the blood homology, as the shape of depletion of YIN essence, just be not enough to carry yang-energy, so sun is born in the life of thing; The one-tenth of thing; Be formed in the moon, only have cloudy essence sufficient, yang-energy is vigorous, and coordinated balances both, and human body could be healthy.
The kidney being the origin of congenital constitution, is the root of human body reproductive development, and the motive power of internal organs functional activity, the vital essence of kidney can be divided into kidney yin, kidney yang two aspects from effect, and the dynamic equilibrium of human body is kept in kidney yin rain kidney yang mutual dependence for existence, restriction mutually.After this balance is destroyed, the pathological change that will occur that kidney yin, kidney yang decline partially or partially contain, partially declining as kidney yin can not sun processed, the pathological changes that hyperactivity of YANG due to deficiency of YIN just occurs, it is deficiency of the kidney yin, show as dysphoria with feverish sensation in the chest palms and soles, dizziness and tinnitus, insomnia forgetfulness, night sweat, the man premature ejaculation of passing out semen, woman's infrequent menstruation amenorrhea, stool constipation, the performances such as the few tongue thready and rapid pulse of red tongue.Kidney yang partially declines and is to show as pale complexion or dark by insufficiency of kidney-YANG.Lassitude, impotence in male premature ejaculation, woman's infertility, enuresis edema, Diarrhoea etc.From these symptoms, suffer from a deficiency of the kidney and not only show as the change of sexual function aspect, also comprising a series of variations of whole body, therefore the accent of kidney is mended and occupied very important position in the human life activity.If congenital defect will lose and support the day after tomorrow, or prolonged illness consumption wound, the kidney store essential substances is not enough, and " water loses common source, and the disease of the deficiency of YIN is folded out on the one hand; Fire declines it, yang deficiency levy storied." hectic fever, flushed face in the afternoon will appear in the imbalance of YIN and YANG of the moon, sexual hypofunction and with the term syndrome etc.
The present invention suits the remedy to the case for insufficiency of kidney-YANG exactly, the deficiency of kidney-QI of suffering from a deficiency of the kidney and generally referring to centered by deficiency of kidney-essence and causing therefrom, the syndromes such as deficiency of kidney-QI, insufficiency of kidney-YANG.Various Symptoms are: 1, deficiency of kidney-essence: brains inanition, the hypophrenia, forgetful, insomnia, lusterless complexion, order week blackout, heavy, weakness of the lower extremities (or it is weak to wither), geromorphism, sexual impotence, lingering diarrhea, teenager be hypoevolutism memory children's's five kinds of growth retardation five kinds of flaccidity in infant etc.; 2, deficiency of kidney-QI: deficient in energyly, quiet think to sleep, two orders are unable, easy to catch cold, seminal emission, spermatorrhea or moving asthma, incontinence of feces, clear urine in large amounts or the enuresis, frequent micturition, acraturesis (or not smooth), the heeltap, incontinence of urination and defecation etc. are even arranged.3, deficiency of the kidney yin: emaciated physique, dysphoria with feverish sensation in the chest palms and soles, thirsty and dry pharynx (or pharynx pain repeatedly), osteopyrexia and fever, night sweat, Hiccough and deaf, yellowish or reddish urine, the few tongue of red tongue, deficient pulse are counted accurately etc.; 4, insufficiency of kidney-YANG: be afraid of cold, limb is cool, easily have a cold or cold sterile, the Diarrhoea of hyperhidrosis, inappetence, sexual impotence, essence (palace) or dysuria even edema, light red tongue or fat indentation, deep-slow pulse etc. are arranged greatly.
Summary of the invention
Purpose of the present invention, be to provide a kind of traditional Chinese medicine secret recipe handed down from one's ancestors for the treatment of deficiency of the kidney yin and insufficiency of kidney-YANG, not only on formula unlike the prior art, and all very easy on preparation method, using method, more Patients with Kidney Deficiency Type is reduced painful, Chinese medicine among the people has obtained succession and has developed.
This preparation be director Lv Ziwang based on motherland's medical science to pathogenetic understanding of suffering from a deficiency of the kidney, theory of Chinese medical science thinks, suffering from a deficiency of the kidney is mainly that battalion defends deficiency, negative and positive of qi and blood imbalance, or deficiency of both the liver and kidney, weakened body resistance and evil gathering felt exopathogen again, or double congestion.Excavate the traditional Chinese medical science and enrich clinical experience, in conjunction with modern pharmacological research, carry out that lot of experiments draws, each amounts of components all has good therapeutic effect in the following weight parts scope.
Radix Angelicae Sinensis 50-60g, Rhizoma Chuanxiong 50-60g, Fructus Rosae Laevigatae 20-40g, Cortex Eucommiae 50-60g, Radix Glycyrrhizae 20-40g, Poria 50-60g, Herba Epimedii 20-40g, Radix Rehmanniae Preparata 100-120g.
Be preferably: Radix Angelicae Sinensis 55g, Rhizoma Chuanxiong 55g, Fructus Rosae Laevigatae 30g, Cortex Eucommiae 55g, Radix Glycyrrhizae 30g, Poria 55g, Herba Epimedii 30g, Radix Rehmanniae Preparata 110g.
Wherein Radix Angelicae Sinensis, enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Rhizoma Chuanxiong enters blood gas, and the capable blood of gas is lived, and blood wind and cold can be fallen apart, and damp in can dry blood, therefore wind, suffering from a deficiency of the kidney due to cold, wet all can be used, has dissipating depression of QI and transfers liver, and it is smooth that blood stagnation, the stagnation of QI all can affect the accent of Liver Channel QI and blood, and liver governing tendons can be selected during the contracture of flesh muscle; The little hardship of Radix Fructus Rosae Laevigatae, puckery, tepor, fruit is sweet flat.The convergence arresting seminal emission is arranged, the effect of intestine-stabling and anti-diarrheal.Cure mainly lumbago, seminal emission, the enuresis, nephritis, night sweat, sexual impotence etc.Cortex Eucommiae sweet in the mouth, warm in nature.Return liver, kidney, stomach warp, have liver and kidney tonifying, bone and muscle strengthening, Chong and Ren Meridians regulating, solid through antiabortive effect.The Radix Glycyrrhizae invigorating the spleen and replenishing QI, the collateral dredging arteries and veins has the effect of warming middle-JIAO emergency and coordinating the actions of various ingredients in a prescription.The Poria slightly sweet flavor is flat, enters the heart, lung, spleen channel.Has eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Herba Epimedii has kidney-replenishing, bone and muscle strengthening, efficacy of dispelling wind.Radix Rehmanniae Preparata sweet in the mouth tepor matter profit, the YIN nourishing of both having enriched blood again can vital essence replenishing and marrow benifiting.
Radix Angelicae Sinensis, Rhizoma Chuanxiong, Fructus Rosae Laevigatae, the Cortex Eucommiae, Radix Glycyrrhizae, Poria, Herba Epimedii, Radix Rehmanniae Preparata share, have that warming the meridian is cold loose, relaxing muscles and tendons to promote blood circulation, QI invigorating blood stasis dispelling, treatment of arthritis and promoting collateral and channels, reducing swelling and alleviating pain, dissipating blood stasis dry, suppressing the hyperactive liver to relieve the wind syndrome, the active calmness of dispeling the wind, calm the frightened, blood stasis dispelling dissipating blood stasis, the circulation of qi promoting of calming the nerves, lax flesh muscle, peace spleen are enriched blood, yin nourishing is promoted blood circulation, saprophytic new, the blood stasis removing and clots absorbing of bone and muscle strengthening, change, soothing liver-QI kidney tonifying, continuous muscle are promoted blood circulation, invigorating the spleen and replenishing QI, dissipating depression of QI are transferred liver, stretch muscle the live stasis of blood, stimulate the menstrual flow easypro network, invigorating striae of the skin, the effect of strengthening vital QI to eliminate pathogenic factors.Attack and mend synchronously, amount GSMC is large, and heresy goes just to set, and the victory of effect speed is got in righting fast.
Medicine of the present invention has the following advantages:
1, utilize the comprehensive function of the medicine of respectively distinguishing the flavor of, can implement effectively treatment to suffering from a deficiency of the kidney, short treating period, cure rate is high.
2, painless noinvasive, easy to use, comfortable, safety.
3, respectively distinguish the flavor of medicine source is easy to get, and is easy to promote.
4, production technology is simple, and is cheap.
5, Product transport is easy to carry, is easy to deposit storage.
Another object of the present invention is to provide the preparation method of said medicine.
The specific embodiment
Choose high-quality following traditional Chinese medicines material Radix Angelicae Sinensis, Rhizoma Chuanxiong, Fructus Rosae Laevigatae, the Cortex Eucommiae, Radix Glycyrrhizae, Poria, Herba Epimedii, Radix Rehmanniae Preparata, following column weight amount proportioning mixing Radix Angelicae Sinensis 58g, Rhizoma Chuanxiong 58g, Fructus Rosae Laevigatae 30g, Cortex Eucommiae 58g, Radix Glycyrrhizae 30g, Poria 58g, Herba Epimedii 30g, Radix Rehmanniae Preparata 118g take, concentrate, and produce through measures such as high temperature sterilize, fungus-proof antisepsis.
Instructions of taking: every day three times, each ball, the warm water (medicine) being taken before meal is used.
Physics's toxicity test
One, test material:
Laboratory animal: mouse NIH, body weight 25-28g, magnetic half and half; Rats Wistar body weight 130-160g, male and female half and half, the medical college zoopery center, feedstuff effluent north of rat, mice provides.
Tested medicine:
1, the negative and positive Bushen Pills of medicine of the present invention: embodiment preparation, three is used with distilled water diluting when equal amount of mixture is tested in batches.
2, positive control medicine: loins-strengthening and kidney-invigorating bolus.
Two, test method and result:
(1) get 40 of the healthy mices of body weight 25-28g, male and female half and half, be divided into respectively four groups by sex and body weight, 20 every group, take medicine of the present invention for 1,2,3 group, dosage is respectively 8.6g biology/kg/d, 6.4g biology/kg/d, 4.2g biology/kg/d takes the positive control drug loins-strengthening and kidney-invigorating bolus for the 4th group, dosage is 8g biology/kg/d, is used in conjunction 15 days.
Result of the test: 1,2,3 groups of mices obviously strengthen than 4 groups of sexual excitation degree, and 1,2,3 group of mice number of copulations increases by twice than the number of copulations of 4 groups of mices average every day.
Result of the test shows that medicine of the present invention has obvious excitation to the central nervous system, thus medicine of the present invention for balance the body function equilibrium, QI invigorating, enrich blood, slow down aging strengthens metabolism, neurolysis, sexual hypofunction have the treatment foundation.
(2) get 40 of body weight 100-130g healthy rats, male and female half and half, measure serum total cholesterol (TC), high density lipoprotein (HDL-C) also calculates TC/HDL-C ratio, then be divided at random four groups, every group 10,1,2,3 groups of capsules of taking respectively embodiment of the present invention preparation, dosage is respectively dosage and is respectively 8.6g biology/kg/d, 6.4g biology/kg/d, 4.2g biology/kg/d, take the positive control drug loins-strengthening and kidney-invigorating bolus for the 4th group, dosage is 6g biology/kg/d, be used in conjunction 15 days, result of the test shows that medicine of the present invention has antidepressant, improve the effect of immunity.
The animal acute toxicity test of pharmaceutical preparation of the present invention
One, test material
(1) animal mouse NIH kind male and female half and half, body weight 20-25g, and medical college zoopery center, effluent north provides.
(2) tested medicine: the negative and positive Bushen Pills that the embodiment of the present invention is prepared is diluted with distilled water into suspension.
Two, test method and result:
The mice maximum tolerance determination: get 20 of healthy mices, male and female half and half, in 24 hours minutes three groups, the each 0.6ml/ of gavage intestinal only, gross weight 1.8ml is equivalent to protozoa 4.0g, i.e. 100g biology/kg/d is equivalent to 857 times of clinical 65 kilograms of people.After the mice administration routinely feedstuff had no animal dead in 12 days and toxic reaction do not occur.
Long term toxicity test:
Chinese medicine preparation of the present invention to mice by 7.69,19.18 and the 43.21g biology/12 weeks of kg continuous use (1.0ml/100g body weight, every day 2 times) and after 3 weeks of drug withdrawal, result shows, Chinese medicine preparation of the present invention all has no significant effect indexs such as the hair of rat, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat, the internal organs naked eyes do not find that difference changes and the histological examination result shows, after 12 weeks of medication and 3 weeks of drug withdrawal, each internal organs of rat are all without obviously changing.Illustrate that toxicity is little after Chinese medicine preparation of the present invention is to the rat long-term prescription, also there is no difference reaction, application safety after drug withdrawal.
The report of drug accumulation toxicity test:
Test method: select 20 healthy mices, each 10 of male and female, the dosage design was first phase in every 5 days, each issue dosage is respectively 0.10LD50.0.15LD50,0.22LD50.0.34LD50,0.50LD50, and the LD50 female, male mice of this sample is 5000m part/kBW (five dosage be 500,750,1100,1700,2500m part/k part BW).Weighed once in every 5 days, and adjusted dosage, press 0.1ml/10 part BW per os gavage.After 20 days, animal occurs without death condition, and off-test is pressed ascending-dose to tested material after 20 days, and female, buck all occurs without death condition.
One, irritation test:
Give the white mouse vaginal dosing, observed 5 with 200 times of the clinical consumption per day of this product endo-medicine.All animals are strong as a result deposits, its activity, diet, scared, and Excreta is no abnormal, has no toxic reaction.White mouse vagina and damaged skin are carried out irritation test, there are no irritative response and other untoward reaction.
Two, test index
(1) general status comprises body weight, diet, emotion, movable energy.
(2) hemogram checking: red blood cell count(RBC), numeration of leukocyte, platelet count, hemogram etc., quantitative hemoglobin counting.
(3) biochemical analysis, serum albumin quantitatively, cholesterol, blood sugar quantitative.
(4) pathologic diagnosis: get the half animal after experimental result and weigh, sacrificed by decapitation is got blood, and solution is treated others for earnest simultaneously, liver, kidney, lung, brain, spleen, gastrointestinal, bladder, adrenal gland do physical organization and check.
Three, result of the test: show through rat chronic toxicity test, with the heavy dose of coloclysis of medicine of the present invention six months, growth, the body weight of rat increased, brain, liver, renal function are all had no side effect.Each histoorgan, the blood circulation of rat are not found that infringement changes, medication group and matched group comparison no significant difference, illustrate that medicine of the present invention has QI invigorating, the drug effect such as enrich blood, avirulence.
The clinical observation on the therapeutic effect test of medicine composite for curing nephrasthenia syndrome of the present invention:
Observe case and be the out-patient, meet the diagnostic criteria that Chinese medical discrimination is suffered from a deficiency of the kidney, and strictly grasp the Excluded cases standard, amount to 400 examples, wherein fear of cold, soreness of the waist and knees 210 examples, nephrasthenia syndrome person 80 examples, menoxenia person's 40 examples, sexual hypofunction person's 229 examples, decreased cardiac function person 70 examples.Be divided at random treatment group and matched group, treatment group 300 examples wherein, male 165 examples, female's 135 examples, age 30-75 year, 49.5 years old mean age, course of disease 1-5; Matched group 100 examples, male 56 examples, female's 44 examples, age 32-78 year, 50 years old mean age, course of disease 1-5, from distribution situations such as two groups of ages, the course of disease, the state of an illness, without significant difference, P>0.05.
One, test case standard
1, include the case standard in: soreness of the waist and knees, fear of cold, hyposexuality, forgetful, lassitude, insomnia, dreaminess, cardiopalmus, weak, breathe hard, dizzy, enlarged tongue is large, tongue is white, a little less than deep-slow pulse.Meet the dialectical person of above insufficiency of kidney-YANG, can include the test case in.
2, Excluded cases standard:
(1) gestation or women breast-feeding their children, allergic constitution reaches written or printed documents medicine allergy sufferers.
(2) merge severe cardiac cerebrovascular, the primary diseases such as Liver and kidney, psychotic.
(3) deficiency of the kidney yin patient and not medication in accordance with regulations can't judge curative effect, or data is not congruent affects the treatment or safety judgement person.
Two, observation procedure
1, medication and dosage
Treatment group: take the prepared negative and positive Bushen Pills of the embodiment of the present invention 1, every day 3 times is oral, each 1 ball.
Matched group: take loins-strengthening and kidney-invigorating bolus, every day 3 times is oral, each 1 ball.
2, treat the course for the treatment of
The all cases medication 1 month was a course for the treatment of.
3, safety observation
(1) just routine test of hematuria
(2) darling renal function inspection
Respectively check 1 time before and after medication
4, health giving quality observation
Related symptoms, sign change
Three, curative effect determinate standard
1, clinical recovery: the symptom of suffering from a deficiency of the kidney, sign disappear.
2, produce effects: the symptom of suffering from a deficiency of the kidney, sign are obviously improved.
3, effective: the symptom of suffering from a deficiency of the kidney, sign all take a favorable turn.
4, invalid: the symptom of suffering from a deficiency of the kidney, sign are unchanged.
Four, observed result
1, curative effect relatively
Table 1 general curative effect relatively
Group Recovery from illness Produce effects Effectively Invalid Total effective rate %
Treatment group 151 104 40 5 97.2
Matched group 20 43 24 13 87
As known from Table 1, two groups of curative effects compare, and there were significant differences, P<0.05
Before and after the treatment of table 2 treatment group, cardinal symptom relatively
Project Number of cases before treatment Number of cases after treatment Total effective rate %
Soreness of the waist and knees 281 14 95.1
Fear of cold 107 9 93.7
Libido disappears 235 16 92.3
Insomnia and dreamful sleep 185 12 96.2
Lassitude 194 11 95.8
Weak dizziness and tinnitus 165 21 85.2
Menoxenia 34 5 90.7
Forgetful 159 14 94.8
As shown in Table 2, this medicine has good improvement effect to above-mentioned kidney symptom.
Before and after table 3 treatment of control group, cardinal symptom relatively
Project Number of cases before treatment Number of cases after treatment Total effective rate %
Soreness of the waist and knees 85 16 80.1
Fear of cold 38 8 81.6
Libido disappears 45 6 85.2
Insomnia and dreamful sleep 37 7 82.4
Lassitude 49 12 75.3
Weak dizziness and tinnitus 74 13 80.5
Menoxenia 10 6 60
Forgetful 50 5 90
By as seen from Table 3, aspect doing well,improving, treatment group obviously is better than matched group, and there is significant difference P<0.05.
2, observed result shows, medicine of the present invention is treatment kidney deficiency determined curative effect, and general curative effect is better than the positive control medicine, in the clinical application process, for finding any untoward reaction, illustrates that safety of medicine of the present invention is effective, without toxicity.

Claims (3)

1. the Chinese medicine that treatment is suffered from a deficiency of the kidney, is characterized in that: be to be made by the following traditional Chinese medicines material: Radix Angelicae Sinensis, Rhizoma Chuanxiong, Fructus Rosae Laevigatae, the Cortex Eucommiae, Radix Glycyrrhizae, Poria, Herba Epimedii, Radix Rehmanniae Preparata.
2. a kind for the treatment of according to claim 1 Chinese medicine of suffering from a deficiency of the kidney, is characterized in that: be to press column weight amount proportioning to make: Radix Angelicae Sinensis 50-60g, Rhizoma Chuanxiong 50-60g, Fructus Rosae Laevigatae 20-40g, Cortex Eucommiae 50-60g, Radix Glycyrrhizae 20-40g, Poria 50-60g, Herba Epimedii 20-40g, Radix Rehmanniae Preparata 100-120g.
3. a kind for the treatment of according to claim 2 Chinese medicine of suffering from a deficiency of the kidney, it is characterized in that: each raw material optimum ratio weight is: Radix Angelicae Sinensis 58g, Rhizoma Chuanxiong 58g, Fructus Rosae Laevigatae 30g, Cortex Eucommiae 58g, Radix Glycyrrhizae 30g, Poria 58g, Herba Epimedii 30g, Radix Rehmanniae Preparata 118g.
CN2013100971241A 2013-03-26 2013-03-26 Traditional Chinese medicine for treating kidney deficiency Pending CN103142754A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104510803A (en) * 2015-01-09 2015-04-15 佛山市顺德区宝铜金属科技有限公司 Chinese patent medicine for kidney-yang deficiency arthralgia
CN106421224A (en) * 2016-11-11 2017-02-22 东莞市百替生物科技有限公司 Traditional Chinese medicine preparation for treating kidney deficiency and preparation method
CN106511620A (en) * 2017-01-17 2017-03-22 三金集团湖南三金制药有限责任公司 Traditional Chinese medicine preparation and preparing method and application thereof
CN114848771A (en) * 2021-01-20 2022-08-05 新疆医联惠康医疗服务有限公司 Medicinal sugar for improving immunity and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102920917A (en) * 2012-11-22 2013-02-13 王艳武 Medicine for treating deficient cold type epigastric pain

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102920917A (en) * 2012-11-22 2013-02-13 王艳武 Medicine for treating deficient cold type epigastric pain

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104510803A (en) * 2015-01-09 2015-04-15 佛山市顺德区宝铜金属科技有限公司 Chinese patent medicine for kidney-yang deficiency arthralgia
CN106421224A (en) * 2016-11-11 2017-02-22 东莞市百替生物科技有限公司 Traditional Chinese medicine preparation for treating kidney deficiency and preparation method
CN106511620A (en) * 2017-01-17 2017-03-22 三金集团湖南三金制药有限责任公司 Traditional Chinese medicine preparation and preparing method and application thereof
CN114848771A (en) * 2021-01-20 2022-08-05 新疆医联惠康医疗服务有限公司 Medicinal sugar for improving immunity and preparation method thereof

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Application publication date: 20130612