CN106421224A - Traditional Chinese medicine preparation for treating kidney deficiency and preparation method - Google Patents
Traditional Chinese medicine preparation for treating kidney deficiency and preparation method Download PDFInfo
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- CN106421224A CN106421224A CN201610992095.9A CN201610992095A CN106421224A CN 106421224 A CN106421224 A CN 106421224A CN 201610992095 A CN201610992095 A CN 201610992095A CN 106421224 A CN106421224 A CN 106421224A
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating kidney deficiency and a preparation method. The traditional Chinese medicine preparation is made up of the following raw materials: 90-150 parts of angelica sinensis, 120-180 parts of radix angelicae pubescentis, 120-180 parts of gentiana macrophylla, 120-180 parts of achyranthes bidentata, 120-180 parts of ligusticum wallichii, 120-180 parts of atractylodes, 120-180 parts of raspberry, 120-180 parts of homalomena rhizome, 300-500 parts of astragalus, 40-100 parts of cassia twig, 200-400 parts of parasitic loranthus, 200-400 parts of caulis spatholobi, 170-230 parts of the rosa laevigata, 170-230 parts of gorgon fruit, 170-230 parts of papaya, 40-80 parts of licorice, 70-130 parts of morinda officinalis, 70-130 of herba epimedii, 90-150 parts of cistanche deserticola, 70-130 parts of dodder, 0.001-0.002 part of stevioside, and 0.001-0.003 part of sodium benzoate. The traditional Chinese medicine preparation has the function of warming the kidney to strengthen waist, and invigorating meridians, is remarkable in the effect, and can be taken for a long time, and the patient is easy to accept.
Description
Technical field
The present invention relates to the field of Chinese medicines, more particularly to a kind of Chinese medicine preparation treating kidney deficiency and preparation method.
Background technology
Kidney deficiency refers to kidney vital essence negative and positive deficiency, and the species of kidney deficiency has a lot, and most common of which is kidney-yin deficiency, kidney-yang deficiency,
The symptom of kidney-yang deficiency is the soreness of waist, coldness of extremities, chilly, or even also oedema, and for the symptom of " trembling with fear ", sexual function is bad to be also resulted in
Kidney-yang deficiency；The symptom of kidney-yin deficiency is " hot ", mainly has the soreness of waist, scorching, night sweat, abnormal sweating, dizziness, tinnitus etc., modern science proves,
When there is kidney deficiency in people, no matter kidney-yin deficiency or kidney-yang deficiency, all can lead to the reduction of the immunocompetence of people, the immunocompetence of kidney
Reduce, and the microcirculqtory system of kidney also can be blocked, kidney network presents obstructed, and the symptom of symptom kidney deficiency is：Decrease of memory
Failure of memory, absent minded, deficient in energy, operating efficiency reduces；Unhappy mood is often difficult to automatic control, dizzy, easily
Anger, irritated, anxiety, depression etc.；Self-doubt lack confidence, self-doubt, work there is not enthusiasm, and life there is not passion, does not have target
And direction；Sexual function reduces man's property interest and reduces, and sexual desire reduces, and impotence or penis are lifted and not hard, seminal emission, involuntary emission, premature ejaculation, show
Micro mirror checks that visible oligozoospermia or motility of sperm lower, sterile；Woman's hypoplasia of uterus, such as hypoplasia of uterus, ovary are early
Decline amenorrhoea, irregular menstruation, and sexual hypoesthesia is infertile etc.；The symptoms such as frequent micturition, urine wait, clear abundant urine；There may also be：Early ageing is forgetful
Insomnia, poor appetite, bone and arthralgia, soreness and weakness of waist and knees, not endurance, weak, hypopsia, sound attenuation, alopecia is white
Send out, epilation or poliosis, tooth mobility Yi Luo etc.；At present, Chinese medicine kidney deficiency research report is increasing, because of it
Small side effects are accepted by vast Patients with Kidney Deficiency Type, using modern science and technology equipment and method, inquire into kidney deficiency etiology and pathogenesis, screening is tested
Card active drug, develops Chinese medicine preparation with strong points, that curative effect affirmative, formulation are easy, is key issue currently urgently to be resolved hurrily.
Content of the invention
For solving above-mentioned technical problem, the present invention provides a kind of Chinese medicine preparation treating kidney deficiency, former by following weight portion
Material is made：Radix Angelicae Sinensis 90-150 part, levisticum 120-180 part, bark of ash 120-180 part, root of bidentate achyranthes 120-180 part, Ligusticum wallichii 120-180 part,
Bighead atractylodes rhizome 120-180 part, raspberry 120-180 part, rhizoma homalonemae 120-180 part, Radix Astragali 300-500 part, cassia twig 40-100 part, mulberry are posted
Raw 200-400 part, reticulate millettia 200-400 part, fruit of Cherokee rose 170-230 part, Gorgon fruit 170-230 part, pawpaw 170-230 part, Radix Glycyrrhizae
40-80 part, Morinda officinalis 70-130 part, HERBA EPIMEDII 70-130 part, saline cistanche 90-150 part, seed of Chinese dodder 70-130 part, stevioside
0.001-0.002 part, Sodium Benzoate 0.001-0.003 part；
The present invention also provides a kind of preparation method of the Chinese medicine preparation treating kidney deficiency, and its preparation process is：
（1）Take raw material Radix Angelicae Sinensis, levisticum, bark of ash, the root of bidentate achyranthes, Ligusticum wallichii, the bighead atractylodes rhizome, raspberry, rhizoma homalonemae, the Radix Astragali, cassia twig, parasitic loranthus, chicken
Blood rattan, the fruit of Cherokee rose, Gorgon fruit, pawpaw, Radix Glycyrrhizae are pulverized with pulverizer, and smashing fineness 100-120 mesh obtains raw material powder, standby；
（2）Raw material Morinda officinalis, HERBA EPIMEDII, saline cistanche, seed of Chinese dodder pulverizer is taken to pulverize, smashing fineness 60-80 mesh, obtain raw material
Powder, standby；
（3）By step（1）Gained raw material powder and step（2）Gained raw material powder adds the water of 8-12 times of raw material gross weight, soaks
0.5-2 hour, heating distillation 2-6 hour, obtain distillate, the dregs of a decoction add the decocting of 4-8 times of raw material gross weight to boil 1-2 time, when
Between be 0.4-0.8 hour, merge decoction liquor and distillate, filter to get filtrate, filtrate is concentrated into 85-95 DEG C surveys relative density and be
The clear cream of 1.00-1.05, adds 85-95% appropriate amount of ethanol after cooling, stirs evenly, 0 to 6 DEG C of refrigeration 20-30 hour, filters, filtrate subtracts
Push back receipts ethanol to no alcohol taste, filtrate is concentrated into the medicinal extract that 50-60 DEG C of relative density is 1.15-1.25, standby；
（4）By step（3）Middle gained medicinal extract is put in Agitation Tank, adds the purified water of medicinal extract weight 3-6 times amount to be heated to seething with excitement,
Stirring 15-25 minute, micro-boiling rises insulation 10-15 minute, forms liquid, places, is cooled to room temperature, standby；
（5）Stevioside, Sodium Benzoate is taken to be respectively crushed into 500-600 mesh, standby；
（6）By step（4）Middle gained liquid adds the stevioside after pulverizing, Sodium Benzoate dissolving stirring, so that liquid is mixed,
Filtered with centrifuge after stirring 15-25 minute, at 60-65 DEG C, carry out twice homogenization under the conditions of 20-30MPa, then adjust pH
For 6.5-7.0, obtain joining liquid, standby；
（7）By step（6）Middle gained joins the clean vial packing of liquid, using ultra high temperature short time sterilization, obtains final product treatment kidney deficiency
Chinese medicine preparation.
Preferably in scheme, a kind of described Chinese medicine preparation treating kidney deficiency, it is made up of the raw material of following weight portion：Radix Angelicae Sinensis
120 parts, 150 parts of levisticum, 150 parts of bark of ash, 150 parts of the root of bidentate achyranthes, 150 parts of Ligusticum wallichii, 150 parts of the bighead atractylodes rhizome, 150 parts of raspberry, rhizoma homalonemae 150
Part, 400 parts of the Radix Astragali, 70 parts of cassia twig, 300 parts of parasitic loranthus, 300 parts of reticulate millettia, 200 parts of the fruit of Cherokee rose, 200 parts of Gorgon fruit, pawpaw 200
Part, 60 parts of Radix Glycyrrhizae, 100 parts of Morinda officinalis, 100 parts of HERBA EPIMEDII, 120 parts of saline cistanche, 100 parts of the seed of Chinese dodder, 0.0015 part of stevioside, benzene
0.002 part of sodium formate；
Its preparation process is：
（1）Take raw material Radix Angelicae Sinensis, levisticum, bark of ash, the root of bidentate achyranthes, Ligusticum wallichii, the bighead atractylodes rhizome, raspberry, rhizoma homalonemae, the Radix Astragali, cassia twig, parasitic loranthus, chicken
Blood rattan, the fruit of Cherokee rose, Gorgon fruit, pawpaw, Radix Glycyrrhizae are pulverized with pulverizer, and smashing fineness 100 mesh obtains raw material powder, standby；
（2）Raw material Morinda officinalis, HERBA EPIMEDII, saline cistanche, seed of Chinese dodder pulverizer is taken to pulverize, smashing fineness 80 mesh, obtain raw material powder, standby
With；
（3）By step（1）Gained raw material powder and step（2）Gained raw material powder adds the water of 12 times of raw material gross weight, soaks 0.5
Hour, heating distillation 4 hours, obtain distillate, the dregs of a decoction add the decocting of 6 times of raw material gross weight to boil 2 times, the time is 0.5 hour,
Merge decoction liquor and distillate, filter to get filtrate, filtrate is concentrated into 85 DEG C and surveys the clear cream that relative density is 1.00, adds after cooling
85% appropriate amount of ethanol, stirs evenly, and 5 DEG C refrigerate 20 hours, filter, to no alcohol taste, filtrate is concentrated into 60 DEG C of phases to decompression filtrate recycling ethanol
It is 1.25 medicinal extract to density, standby；
（4）By step（3）Middle gained medicinal extract is put in Agitation Tank, adds the purified water of medicinal extract weight 6 times amount to be heated to seething with excitement, stirs
Mix 15 minutes, micro-boiling rises insulation 10 minutes, form liquid, place, be cooled to room temperature, standby；
（5）Stevioside, Sodium Benzoate is taken to be respectively crushed into 600 mesh, standby；
（6）By step（4）Middle gained liquid adds the stevioside after pulverizing, Sodium Benzoate dissolving stirring, so that liquid is mixed,
Stirring was filtered with centrifuge after 15 minutes, at 60 DEG C, carried out twice homogenization under the conditions of 20MPa, then adjusted pH for 7.0, obtained
To joining liquid, standby；
（7）By step（6）Middle gained joins the clean vial packing of liquid, using ultra high temperature short time sterilization, obtains final product treatment kidney deficiency
Chinese medicine preparation.
Used by the present invention, the pharmacology of Chinese medicine material medicine is as follows：
Radix Angelicae Sinensis：Meridian distribution of property and flavor：Sweet, acrid, warm, Return liver, the heart, the spleen channel；Indication：Replenishing and activating blood, menstruction regulating and pain relieving, relax bowel；
For blood deficiency chlorosis, dizziness palpitaition, irregular menstruation, closed dysmenorrhea, asthenia cold abdominalgia, dry constipation of intestines, arthralgia due to wind-dampness, injury from falling down,
Ulcer sores.
Levisticum：Meridian distribution of property and flavor：Pungent, bitter, tepor, return kidney, bladder warp；Indication：Dispelling wind and eliminating dampness, numbness relieving and pain relieving；For
Wind-cold-dampness arthralgia, lumbocrural pain, few the moon volt wind headache.
Bark of ash：Meridian distribution of property and flavor：Pungent, bitter, put down, return stomach, liver, gallbladder channel；Indication：Wines used as antirheumatic, clearing away damp-heat, stopping numbness pain；With
In arthralgia due to wind-dampness, muscle arteries and veins contraction, joint is ached, afternoon tidal fever, infantile malnutrition generates heat.
The root of bidentate achyranthes：Meridian distribution of property and flavor：Bitter, sour, put down, return liver and kidney channel；Indication：Filling liver kidney, strengthening the bones and muscles, dispelling stasis of blood and stimulating the menstrual flow, draw blood
Descending；For soreness of waist and knee joint, muscles and bones is powerless, Amenorrhea note of the ancient Chinese lump in the abdomen, dizziness due to hyperactivity of liver-YANG.
Ligusticum wallichii：Meridian distribution of property and flavor：Pungent, temperature, Return liver, courage, pericardium channel；Indication：Blood-activating and qi-promoting, wind-expelling pain-stopping；For the moon
Through uncomfortable, closed dysmenorrhea, lump in the abdomen is suffered from abdominal pain, chest side of body shouting pain, tumbling and swelling, headache, arthralgia due to wind-dampness.
The bighead atractylodes rhizome：Meridian distribution of property and flavor：Bitter, sweet, temperature, returns spleen, stomach；Indication：Strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, peace
Tire；For spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, fetal irritability；Rhizoma Atractylodis Macrocephalae invigorating the spleen, and stomach, antiabortive；With
In spleen eating less, loose stool of having loose bowels, fetal irritability.
Raspberry：Meridian distribution of property and flavor：Sweet, sour, temperature, return kidney, bladder warp；Indication：Kidney-nourishing, controlling nocturnal emission with astringent drugs, contracting urine；For kidney deficiency
The enuresis, frequent urination, impotence and premature ejaculation, emission and spermatorrhea.
Rhizoma homalonemae：Meridian distribution of property and flavor：Hardship, pungent, temperature, return liver and kidney channel；Indication：Wines used as antirheumatic, muscle reinforcing and bone strengthening；Wet for chill
Numbness, waist and knee crymodynia, lower limb contraction.
The Radix Astragali：Meridian distribution of property and flavor：Sweet, temperature, return lung, the spleen channel；Indication：Invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, sore is given birth to
Flesh；For treatment deficiency of vital energy weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult
Burst, bursts for a long time and does not holds back, flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes；Chronic rephrilis protinuria, diabetes.
Cassia twig：Meridian distribution of property and flavor：Acrid, sweet, warm, the thoughts of returning home, lung, bladder warp；Indication：Sweating expelling pathogenic factors from muscles and skin, warming meridian is supporing yang
Change gas, flat gas that spins；For anemofrigid cold, coldness and pain in the epigastrium, blood trembles with fear Amenorrhea, joint pain, phlegm and retained fluid, oedema, palpitaition, run quickly globefish.
Parasitic loranthus：Meridian distribution of property and flavor：Bitter, sweet, flat, Return liver, kidney channel；Effect：Wines used as antirheumatic, filling liver kidney, strengthening the bones and muscles, antiabortive；Main
Control：For arthralgia due to wind-dampness, soreness of waist and knee joint, blood under threatened abortion, fetal irritability.
Reticulate millettia：Meridian distribution of property and flavor：Bitter, sweet, temperature, return liver and kidney channel；Indication：Enrich blood, promoting blood circulation, dredging collateral；For menstruation not
Adjust, blood deficiency chlorosis, paralysis and numbness, arthralgia due to wind-dampness.
The fruit of Cherokee rose：Meridian distribution of property and flavor：Sour, sweet, puckery, put down, return kidney, bladder, large intestine channel；Indication：Astringent sperm contracting urine, puckery intestines stop
Rush down；For emission and spermatorrhea, enuresis frequent micturition, uterine bleeding under band, protracted dysentery and diarrhea.
Gorgon fruit：Meridian distribution of property and flavor：Sweet, puckery, put down, returns spleen, kidney channel；Indication：Supplementing the kidney to control the nocturnal, tonifying spleen and stopping diarrhea, tonifying spleen and stopping diarrhea；
For emission, enuresis frequent micturition, insufficiency of the spleen chronic diarrhea, gonorrhoea, under band.
Pawpaw：Meridian distribution of property and flavor：Acid, temperature, Return liver, the spleen channel；Indication：Flat liver relaxing muscles and tendons, stomach dampness elimination；Arrest for arthritis with fixed pain caused by dampness
Contraction, waist and knee joint acid weight pain, convulsion of vomiting and diarrhoea, tinea pedis oedema.
Radix Glycyrrhizae：Mild-natured, sweet, the thoughts of returning home, spleen, lung, stomach；Effect：Help；Indication：Invigorate the spleen and benefit qi, clearing heat and detoxicating,
Expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription；For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs
Contraction urgency pain, carbuncle sore tumefacting virus, alleviate drug toxicity, strong.
Morinda officinalis：Meridian distribution of property and flavor：Sweet, pungent, tepor, return kidney, Liver Channel；Indication：Kidney-replenishing, strengthening the bones and muscles, wines used as antirheumatic；With
In impotence and seminal emission, uterus cold infertile, irregular menstruation, few abdomen crymodynia, arthralgia due to wind-dampness, muscles and bones impotence.
HERBA EPIMEDII：Taste is pungent, sweet, warm in nature, return liver warp, kidney channel；Effect：Tonifying kidney and strengthening yang, dispelling wind and eliminating dampness, strong muscle key bone；Cure mainly：
Impotence and seminal emission, empty cold sterile, frequent micturition loses Chu, dyspnea and cough due to deficiency of the kidney, soreness and weakness of waist and knees, arthralgia due to wind-dampness, hemiplegia, and four limbs are meciless.
Saline cistanche：Meridian distribution of property and flavor：Sweet, salty, temperature, return kidney, large intestine channel；Indication：Kidney-replenishing, benefiting essence-blood, relax bowel；
For impotence, infertile, soreness and weakness of waist and knees, muscles and bones is powerless, dry constipation of intestines.
The seed of Chinese dodder：Meridian distribution of property and flavor：Sweet, temperature, Return liver, kidney, the spleen channel；Indication：Nourishing liver and kidney, astringent sperm contracting urine, antiabortive, bright
Mesh, antidiarrheal；For impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness and weakness of waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, fetal irritability, spleen
Kidney deficiency is rushed down；Control outward leucoderma.
Beneficial effects of the present invention：Have functions that warm kidney strengthen waist, active promote blood circulation, drug effect is notable, can be suffered from long-term taking
Person is easy to accept.
Specific embodiment
Describe technical scheme with reference to embodiment and experimental example in detail, but protection domain not limited to this.
Embodiment 1
A kind of Chinese medicine preparation treating kidney deficiency, is made up of the raw material of following weight portion：150 parts of Radix Angelicae Sinensis, 180 parts of levisticum, bark of ash 180
Part, 180 parts of the root of bidentate achyranthes, 180 parts of Ligusticum wallichii, 180 parts of the bighead atractylodes rhizome, 180 parts of raspberry, 180 parts of rhizoma homalonemae, 500 parts of the Radix Astragali, 100 parts of cassia twig,
400 parts of parasitic loranthus, 400 parts of reticulate millettia, 230 parts of the fruit of Cherokee rose, 230 parts of Gorgon fruit, 230 parts of pawpaw, 80 parts of Radix Glycyrrhizae, 130 parts of Morinda officinalis,
130 parts of HERBA EPIMEDII, 150 parts of saline cistanche, 130 parts of the seed of Chinese dodder, 0.002 part of stevioside, 0.003 part of Sodium Benzoate；
Its preparation process is：
（1）Take raw material Radix Angelicae Sinensis, levisticum, bark of ash, the root of bidentate achyranthes, Ligusticum wallichii, the bighead atractylodes rhizome, raspberry, rhizoma homalonemae, the Radix Astragali, cassia twig, parasitic loranthus, chicken
Blood rattan, the fruit of Cherokee rose, Gorgon fruit, pawpaw, Radix Glycyrrhizae are pulverized with pulverizer, and smashing fineness 100-120 mesh obtains raw material powder, standby；
（2）Raw material Morinda officinalis, HERBA EPIMEDII, saline cistanche, seed of Chinese dodder pulverizer is taken to pulverize, smashing fineness 60-80 mesh, obtain raw material
Powder, standby；
（3）By step（1）Gained raw material powder and step（2）Gained raw material powder adds the water of 8-12 times of raw material gross weight, soaks
0.5-2 hour, heating distillation 2-6 hour, obtain distillate, the dregs of a decoction add the decocting of 4-8 times of raw material gross weight to boil 1-2 time, when
Between be 0.4-0.8 hour, merge decoction liquor and distillate, filter to get filtrate, filtrate is concentrated into 85-95 DEG C surveys relative density and be
The clear cream of 1.00-1.05, adds 85-95% appropriate amount of ethanol after cooling, stirs evenly, 0 to 6 DEG C of refrigeration 20-30 hour, filters, filtrate subtracts
Push back receipts ethanol to no alcohol taste, filtrate is concentrated into the medicinal extract that 50-60 DEG C of relative density is 1.15-1.25, standby；
（4）By step（3）Middle gained medicinal extract is put in Agitation Tank, adds the purified water of medicinal extract weight 3-6 times amount to be heated to seething with excitement,
Stirring 15-25 minute, micro-boiling rises insulation 10-15 minute, forms liquid, places, is cooled to room temperature, standby；
（5）Stevioside, Sodium Benzoate is taken to be respectively crushed into 500-600 mesh, standby；
（6）By step（4）Middle gained liquid adds the stevioside after pulverizing, Sodium Benzoate dissolving stirring, so that liquid is mixed,
Filtered with centrifuge after stirring 15-25 minute, at 60-65 DEG C, carry out twice homogenization under the conditions of 20-30MPa, then adjust pH
For 6.5-7.0, obtain joining liquid, standby；
（7）By step（6）Middle gained joins the clean vial packing of liquid, using ultra high temperature short time sterilization, obtains final product treatment kidney deficiency
Chinese medicine preparation.
Usage：Oral, 2 times a day, each 15ml.
Embodiment 2
A kind of Chinese medicine preparation treating kidney deficiency, is made up of the raw material of following weight portion：120 parts of Radix Angelicae Sinensis, 150 parts of levisticum, bark of ash 150
Part, 150 parts of the root of bidentate achyranthes, 150 parts of Ligusticum wallichii, 150 parts of the bighead atractylodes rhizome, 150 parts of raspberry, 150 parts of rhizoma homalonemae, 400 parts of the Radix Astragali, 70 parts of cassia twig,
300 parts of parasitic loranthus, 300 parts of reticulate millettia, 200 parts of the fruit of Cherokee rose, 200 parts of Gorgon fruit, 200 parts of pawpaw, 60 parts of Radix Glycyrrhizae, 100 parts of Morinda officinalis,
100 parts of HERBA EPIMEDII, 120 parts of saline cistanche, 100 parts of the seed of Chinese dodder, 0.0015 part of stevioside, 0.002 part of Sodium Benzoate；
Its preparation process is：
（1）Take raw material Radix Angelicae Sinensis, levisticum, bark of ash, the root of bidentate achyranthes, Ligusticum wallichii, the bighead atractylodes rhizome, raspberry, rhizoma homalonemae, the Radix Astragali, cassia twig, parasitic loranthus, chicken
Blood rattan, the fruit of Cherokee rose, Gorgon fruit, pawpaw, Radix Glycyrrhizae are pulverized with pulverizer, and smashing fineness 100-120 mesh obtains raw material powder, standby；
（2）Raw material Morinda officinalis, HERBA EPIMEDII, saline cistanche, seed of Chinese dodder pulverizer is taken to pulverize, smashing fineness 60-80 mesh, obtain raw material
Powder, standby；
（3）By step（1）Gained raw material powder and step（2）Gained raw material powder adds the water of 8-12 times of raw material gross weight, soaks
0.5-2 hour, heating distillation 2-6 hour, obtain distillate, the dregs of a decoction add the decocting of 4-8 times of raw material gross weight to boil 1-2 time, when
Between be 0.4-0.8 hour, merge decoction liquor and distillate, filter to get filtrate, filtrate is concentrated into 85-95 DEG C surveys relative density and be
The clear cream of 1.00-1.05, adds 85-95% appropriate amount of ethanol after cooling, stirs evenly, 0 to 6 DEG C of refrigeration 20-30 hour, filters, filtrate subtracts
Push back receipts ethanol to no alcohol taste, filtrate is concentrated into the medicinal extract that 50-60 DEG C of relative density is 1.15-1.25, standby；
（4）By step（3）Middle gained medicinal extract is put in Agitation Tank, adds the purified water of medicinal extract weight 3-6 times amount to be heated to seething with excitement,
Stirring 15-25 minute, micro-boiling rises insulation 10-15 minute, forms liquid, places, is cooled to room temperature, standby；
（5）Stevioside, Sodium Benzoate is taken to be respectively crushed into 500-600 mesh, standby；
（6）By step（4）Middle gained liquid adds the stevioside after pulverizing, Sodium Benzoate dissolving stirring, so that liquid is mixed,
Filtered with centrifuge after stirring 15-25 minute, at 60-65 DEG C, carry out twice homogenization under the conditions of 20-30MPa, then adjust pH
For 6.5-7.0, obtain joining liquid, standby；
（7）By step（6）Middle gained joins the clean vial packing of liquid, using ultra high temperature short time sterilization, obtains final product treatment kidney deficiency
Chinese medicine preparation.
Usage：Oral, 2 times a day, each 15ml.
Embodiment 3
A kind of Chinese medicine preparation treating kidney deficiency, is made up of the raw material of following weight portion：90 parts of Radix Angelicae Sinensis, 120 parts of levisticum, bark of ash 120
Part, 120 parts of the root of bidentate achyranthes, 120 parts of Ligusticum wallichii, 120 parts of the bighead atractylodes rhizome, 120 parts of raspberry, 120 parts of rhizoma homalonemae, 300 parts of the Radix Astragali, 40 parts of cassia twig,
200 parts of parasitic loranthus, 200 parts of reticulate millettia, 170 parts of the fruit of Cherokee rose, 170 parts of Gorgon fruit, 170 parts of pawpaw, 40 parts of Radix Glycyrrhizae, 70 parts of Morinda officinalis,
70 parts of HERBA EPIMEDII, 90 parts of saline cistanche, 70 parts of the seed of Chinese dodder, 0.001 part of stevioside, 0.001 part of Sodium Benzoate；
Its preparation process is：
（1）Take raw material Radix Angelicae Sinensis, levisticum, bark of ash, the root of bidentate achyranthes, Ligusticum wallichii, the bighead atractylodes rhizome, raspberry, rhizoma homalonemae, the Radix Astragali, cassia twig, parasitic loranthus, chicken
Blood rattan, the fruit of Cherokee rose, Gorgon fruit, pawpaw, Radix Glycyrrhizae are pulverized with pulverizer, and smashing fineness 100-120 mesh obtains raw material powder, standby；
（2）Raw material Morinda officinalis, HERBA EPIMEDII, saline cistanche, seed of Chinese dodder pulverizer is taken to pulverize, smashing fineness 60-80 mesh, obtain raw material
Powder, standby；
（3）By step（1）Gained raw material powder and step（2）Gained raw material powder adds the water of 8-12 times of raw material gross weight, soaks
0.5-2 hour, heating distillation 2-6 hour, obtain distillate, the dregs of a decoction add the decocting of 4-8 times of raw material gross weight to boil 1-2 time, when
Between be 0.4-0.8 hour, merge decoction liquor and distillate, filter to get filtrate, filtrate is concentrated into 85-95 DEG C surveys relative density and be
The clear cream of 1.00-1.05, adds 85-95% appropriate amount of ethanol after cooling, stirs evenly, 0 to 6 DEG C of refrigeration 20-30 hour, filters, filtrate subtracts
Push back receipts ethanol to no alcohol taste, filtrate is concentrated into the medicinal extract that 50-60 DEG C of relative density is 1.15-1.25, standby；
（4）By step（3）Middle gained medicinal extract is put in Agitation Tank, adds the purified water of medicinal extract weight 3-6 times amount to be heated to seething with excitement,
Stirring 15-25 minute, micro-boiling rises insulation 10-15 minute, forms liquid, places, is cooled to room temperature, standby；
（5）Stevioside, Sodium Benzoate is taken to be respectively crushed into 500-600 mesh, standby；
（6）By step（4）Middle gained liquid adds the stevioside after pulverizing, Sodium Benzoate dissolving stirring, so that liquid is mixed,
Filtered with centrifuge after stirring 15-25 minute, at 60-65 DEG C, carry out twice homogenization under the conditions of 20-30MPa, then adjust pH
For 6.5-7.0, obtain joining liquid, standby；
（7）By step（6）Middle gained joins the clean vial packing of liquid, using ultra high temperature short time sterilization, obtains final product treatment kidney deficiency
Chinese medicine preparation.
Usage：Oral, 2 times a day, each 15ml.
Chinese medicine preparation Ureteral Calculus Patients with Kidney Deficiency Type of the present invention 40, clinical report is as follows：
1st, physical data
Clinical observation Patients with Kidney Deficiency Type 40, wherein man 27, female 13, age 30-76 year, average age 47.5 years old.
2nd, diagnostic criteria
Disease：The deficiency in both YIN and YANG of kidney, dysphoria in chestpalms-soles, dizziness and tinnitus cool to fear cold limb, soreness of waist and knee joint, premature ejaculation of passing out semen, chi pulse is weak etc.
Syndrome for common disease.
3rd, treatment method
Using Chinese medicine preparation of the present invention treatment, oral Chinese medicine preparation of the present invention, 2 times a day, each 15ml, is within 7 days a course for the treatment of.
4th, efficacy determination
Cure：Symptom disappears；
Effectively：Clinical symptom relief；
Invalid：Clinical symptoms are no improved or are increased.
5th, treatment results
In clinical treatment Patients with Kidney Deficiency Type 40, cure 38 and account for 95%, effective 2 account for 5%, and invalid 0, total effective rate is 100%.
6th, model case
Case 1：Man, 35 years old, main suit：Weak, deficient, pain along spinal column, One's spirits are drooping, pale complexion, chi pulse is weak, is diagnosed as：Kidney deficiency,
Take 2 courses for the treatment of of Chinese medicine preparation of the present invention, all symptoms are wholly absent, then take 2 courses for the treatment of of Chinese medicine preparation of the present invention, recovery from illness,
After half a year, follow-up is no recurred.
Case 2：Man, 48 years old, ache in patient's waist and knee position, dizzy or tinnitus, Hearing, and the mouth universe swallows dry, dysphoria with smothery sensation, chi pulse
Weak, it is diagnosed as：Kidney deficiency, takes 2 courses for the treatment of of Chinese medicine preparation of the present invention, all symptoms are wholly absent, then take Chinese medicine system of the present invention
2 courses for the treatment of of agent, recovery from illness, follow-up after half a year is no recurred.
Case 3：Female, 43 years old, patient menstrual was continuous, soreness and weakness of waist and knees, and aversion to cold and cold limbs, especially with lower limb for very, is had a dizzy spell, essence
Refreshing dispirited, pale complexion, chi pulse is weak, is diagnosed as：Kidney deficiency, takes 2 courses for the treatment of of Chinese medicine preparation of the present invention, and all symptoms disappear completely
Lose, then take 2 courses for the treatment of of Chinese medicine preparation of the present invention, recovery from illness, follow-up after half a year is no recurred.
It should be pointed out that the specific embodiment more representational example that is the present invention is it is clear that the skill of the present invention
Art scheme is not limited to above-described embodiment, can also have many variations；Those of ordinary skill in the art, clearly public with present invention institute
What what written description that open or according to file was undoubted obtained, all it is considered as this patent scope of the claimed.
Claims (6)
1. a kind of Chinese medicine preparation treating kidney deficiency it is characterised in that：It is made up of the raw material of following weight portion：Radix Angelicae Sinensis 90-150 part,
Levisticum 120-180 part, bark of ash 120-180 part, root of bidentate achyranthes 120-180 part, Ligusticum wallichii 120-180 part, bighead atractylodes rhizome 120-180 part, raspberry
120-180 part, rhizoma homalonemae 120-180 part, Radix Astragali 300-500 part, cassia twig 40-100 part, parasitic loranthus 200-400 part, reticulate millettia
200-400 part, fruit of Cherokee rose 170-230 part, Gorgon fruit 170-230 part, pawpaw 170-230 part, Radix Glycyrrhizae 40-80 part, Morinda officinalis 70-
130 parts, HERBA EPIMEDII 70-130 part, saline cistanche 90-150 part, seed of Chinese dodder 70-130 part, stevioside 0.001-0.002 part, benzoic acid
Sodium 0.001-0.003 part.
2. a kind of Chinese medicine preparation treating kidney deficiency according to claim 1 preparation method it is characterised in that：Its preparation step
Suddenly it is：
（1）Take raw material Radix Angelicae Sinensis, levisticum, bark of ash, the root of bidentate achyranthes, Ligusticum wallichii, the bighead atractylodes rhizome, raspberry, rhizoma homalonemae, the Radix Astragali, cassia twig, parasitic loranthus, chicken
Blood rattan, the fruit of Cherokee rose, Gorgon fruit, pawpaw, Radix Glycyrrhizae are pulverized with pulverizer, and smashing fineness 100-120 mesh obtains raw material powder, standby；
（2）Raw material Morinda officinalis, HERBA EPIMEDII, saline cistanche, seed of Chinese dodder pulverizer is taken to pulverize, smashing fineness 60-80 mesh, obtain raw material
Powder, standby；
（3）By step（1）Gained raw material powder and step（2）Gained raw material powder adds the water of 8-12 times of raw material gross weight, soaks
0.5-2 hour, heating distillation 2-6 hour, obtain distillate, the dregs of a decoction add the decocting of 4-8 times of raw material gross weight to boil 1-2 time, when
Between be 0.4-0.8 hour, merge decoction liquor and distillate, filter to get filtrate, filtrate is concentrated into 85-95 DEG C surveys relative density and be
The clear cream of 1.00-1.05, adds 85-95% appropriate amount of ethanol after cooling, stirs evenly, 0 to 6 DEG C of refrigeration 20-30 hour, filters, filtrate subtracts
Push back receipts ethanol to no alcohol taste, filtrate is concentrated into the medicinal extract that 50-60 DEG C of relative density is 1.15-1.25, standby；
（4）By step（3）Middle gained medicinal extract is put in Agitation Tank, adds the purified water of medicinal extract weight 3-6 times amount to be heated to seething with excitement,
Stirring 15-25 minute, micro-boiling rises insulation 10-15 minute, forms liquid, places, is cooled to room temperature, standby；
（5）Stevioside, Sodium Benzoate is taken to be respectively crushed into 500-600 mesh, standby；
（6）By step（4）Middle gained liquid adds the stevioside after pulverizing, Sodium Benzoate dissolving stirring, so that liquid is mixed,
Filtered with centrifuge after stirring 15-25 minute, at 60-65 DEG C, carry out twice homogenization under the conditions of 20-30MPa, then adjust pH
For 6.5-7.0, obtain joining liquid, standby；
（7）By step（6）Middle gained joins the clean vial packing of liquid, using ultra high temperature short time sterilization, obtains final product treatment kidney deficiency
Chinese medicine preparation.
3. a kind of Chinese medicine preparation treating kidney deficiency according to claim 2 preparation method it is characterised in that：Its preparation step
Suddenly it is：
（1）Take raw material Radix Angelicae Sinensis, levisticum, bark of ash, the root of bidentate achyranthes, Ligusticum wallichii, the bighead atractylodes rhizome, raspberry, rhizoma homalonemae, the Radix Astragali, cassia twig, parasitic loranthus, chicken
Blood rattan, the fruit of Cherokee rose, Gorgon fruit, pawpaw, Radix Glycyrrhizae are pulverized with pulverizer, and smashing fineness 100 mesh obtains raw material powder, standby；
（2）Raw material Morinda officinalis, HERBA EPIMEDII, saline cistanche, seed of Chinese dodder pulverizer is taken to pulverize, smashing fineness 80 mesh, obtain raw material powder, standby
With；
（3）By step（1）Gained raw material powder and step（2）Gained raw material powder adds the water of 12 times of raw material gross weight, soaks 0.5
Hour, heating distillation 4 hours, obtain distillate, the dregs of a decoction add the decocting of 6 times of raw material gross weight to boil 2 times, the time is 0.5 hour,
Merge decoction liquor and distillate, filter to get filtrate, filtrate is concentrated into 85 DEG C and surveys the clear cream that relative density is 1.00, adds after cooling
85% appropriate amount of ethanol, stirs evenly, and 5 DEG C refrigerate 20 hours, filter, to no alcohol taste, filtrate is concentrated into 60 DEG C of phases to decompression filtrate recycling ethanol
It is 1.25 medicinal extract to density, standby；
（4）By step（3）Middle gained medicinal extract is put in Agitation Tank, adds the purified water of medicinal extract weight 6 times amount to be heated to seething with excitement, stirs
Mix 15 minutes, micro-boiling rises insulation 10 minutes, form liquid, place, be cooled to room temperature, standby；
（5）Stevioside, Sodium Benzoate is taken to be respectively crushed into 600 mesh, standby；
（6）By step（4）Middle gained liquid adds the stevioside after pulverizing, Sodium Benzoate dissolving stirring, so that liquid is mixed,
Stirring was filtered with centrifuge after 15 minutes, at 60 DEG C, carried out twice homogenization under the conditions of 20MPa, then adjusted pH for 7.0, obtained
To joining liquid, standby；
（7）By step（6）Middle gained joins the clean vial packing of liquid, using ultra high temperature short time sterilization, obtains final product treatment kidney deficiency
Chinese medicine preparation.
4. a kind of Chinese medicine preparation treating kidney deficiency according to claim 1 it is characterised in that：Raw material by following weight portion
Make：120 parts of Radix Angelicae Sinensis, 150 parts of levisticum, 150 parts of bark of ash, 150 parts of the root of bidentate achyranthes, 150 parts of Ligusticum wallichii, 150 parts of the bighead atractylodes rhizome, 150 parts of raspberry,
150 parts of rhizoma homalonemae, 400 parts of the Radix Astragali, 70 parts of cassia twig, 300 parts of parasitic loranthus, 300 parts of reticulate millettia, 200 parts of the fruit of Cherokee rose, 200 parts of Gorgon fruit,
200 parts of pawpaw, 60 parts of Radix Glycyrrhizae, 100 parts of Morinda officinalis, 100 parts of HERBA EPIMEDII, 120 parts of saline cistanche, 100 parts of the seed of Chinese dodder, stevioside
0.0015 part, 0.002 part of Sodium Benzoate.
5. a kind of Chinese medicine preparation treating kidney deficiency according to claim 1 it is characterised in that：Raw material by following weight portion
Make：150 parts of Radix Angelicae Sinensis, 180 parts of levisticum, 180 parts of bark of ash, 180 parts of the root of bidentate achyranthes, 180 parts of Ligusticum wallichii, 180 parts of the bighead atractylodes rhizome, 180 parts of raspberry,
180 parts of rhizoma homalonemae, 500 parts of the Radix Astragali, 100 parts of cassia twig, 400 parts of parasitic loranthus, 400 parts of reticulate millettia, 230 parts of the fruit of Cherokee rose, Gorgon fruit 230
Part, 230 parts of pawpaw, 80 parts of Radix Glycyrrhizae, 130 parts of Morinda officinalis, 130 parts of HERBA EPIMEDII, 150 parts of saline cistanche, 130 parts of the seed of Chinese dodder, stevioside
0.002 part, 0.003 part of Sodium Benzoate.
6. a kind of Chinese medicine preparation treating kidney deficiency according to claim 1 it is characterised in that：Raw material by following weight portion
Make：90 parts of Radix Angelicae Sinensis, 120 parts of levisticum, 120 parts of bark of ash, 120 parts of the root of bidentate achyranthes, 120 parts of Ligusticum wallichii, 120 parts of the bighead atractylodes rhizome, 120 parts of raspberry,
120 parts of rhizoma homalonemae, 300 parts of the Radix Astragali, 40 parts of cassia twig, 200 parts of parasitic loranthus, 200 parts of reticulate millettia, 170 parts of the fruit of Cherokee rose, 170 parts of Gorgon fruit,
170 parts of pawpaw, 40 parts of Radix Glycyrrhizae, 70 parts of Morinda officinalis, 70 parts of HERBA EPIMEDII, 90 parts of saline cistanche, 70 parts of the seed of Chinese dodder, 0.001 part of stevioside,
0.001 part of Sodium Benzoate.
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|---|---|---|---|---|
| CN101066326A (en) * | 2007-05-11 | 2007-11-07 | 徐朝阳 | Chinese medicine for treating kidney deficiency and its prepn |
| CN103142754A (en) * | 2013-03-26 | 2013-06-12 | 吕子旺 | Traditional Chinese medicine for treating kidney deficiency |
| CN103349753A (en) * | 2013-07-24 | 2013-10-16 | 赵世明 | Traditional Chinese medicine composition for treating kidney deficiency |
| CN103990042A (en) * | 2014-05-20 | 2014-08-20 | 王伟伟 | Traditional Chinese medicine composition for treating frequent micturition caused by kidney deficiency |
| CN105535367A (en) * | 2016-01-20 | 2016-05-04 | 黄庆辉 | Traditional Chinese medicine for treating kidney-deficiency type hypomenorrhea |
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2016
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| CN101066326A (en) * | 2007-05-11 | 2007-11-07 | 徐朝阳 | Chinese medicine for treating kidney deficiency and its prepn |
| CN103142754A (en) * | 2013-03-26 | 2013-06-12 | 吕子旺 | Traditional Chinese medicine for treating kidney deficiency |
| CN103349753A (en) * | 2013-07-24 | 2013-10-16 | 赵世明 | Traditional Chinese medicine composition for treating kidney deficiency |
| CN103990042A (en) * | 2014-05-20 | 2014-08-20 | 王伟伟 | Traditional Chinese medicine composition for treating frequent micturition caused by kidney deficiency |
| CN105535367A (en) * | 2016-01-20 | 2016-05-04 | 黄庆辉 | Traditional Chinese medicine for treating kidney-deficiency type hypomenorrhea |
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Application publication date: 20170222 |