CN103110763A - Traditional Chinese medicine composition for treating urinary calculus and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating urinary calculus and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating urinary calculus and a preparation method thereof. The traditional Chinese medicine composition mainly consists of dianthus superbus, Japanese climbing fern spore, Indian buead, alisma plantagoaquatica, agaric, longhairy antenoron herb, plantain seed, medicinal cyathula root and myrrh. The traditional Chinese medicine composition has the effects of inducing diuresis for treating strangurtia, clearing damp and promoting diuresis, has the effect of well treating pain, dark urine and difficulty of urination caused by urinary calculus, the urinary calculus can be effectively and rapidly treated, and the traditional Chinese medicine composition is an ideal and safe medicine for treating the urinary calculus.
Description
Technical field
The invention discloses a kind of Chinese medicine composition, especially treat Chinese medicine composition of urinary system calculus and preparation method thereof.Genus Chinese medicine field.
Background technology
The urinary system calculus claims again lithangiuria, urinary calculus, is the commonly encountered diseases of urinary system.Refer to form granule or in bulk sample aggregation at urinary system endogenous cause of ill urine concentrating and precipitating; for the urinary system commonly encountered diseases, be apt to occur in person between twenty and fifty, in recent years along with the continuous expansion of environmental pollution; the change of people's living habit, the patient of urinary system calculus is constantly increasing.
The urinary system calculus is the general name of kidney, ureter, bladder, calculus of urethra, and calculus is found in any position of kidney, bladder, ureter and urethra.Position by the lithangiuria place is divided into upper lithangiuria and calculus of lower urinary tract substantially.Upper lithangiuria refers to kidney and ureteral calculus; Calculus of lower urinary tract comprises vesical calculus and calculus of urethra.The existence that the salt that forms the calculus crystal in urine is saturation, suppress crystal formation material deficiency and nuclear matrix will form calculus, and stone composition has calcium oxalate, calcium phosphate and ammonium magnesium phosphate etc.
The pathogenesis of urinary system calculus is comparatively complicated, the traditional Chinese medical science thinks that the etiology and pathogenesis of urinary system calculus carries for " General Treatise on the Cause and Symptoms of Diseases ": the impact of " Zhu Linzhe; therefore bladder is warm also by suffering from a deficiency of the kidney ", think that its etiology and pathogenesis is mainly the unable mistake of the functioning of bladder department of suffering from a deficiency of the kidney, damp-heat accumulation, decoct body fluid. with the passing of time the moon tires out, the poly-stone that forms.
The urinary system calculus is with the violent lumbago of unexpected generation, the few abdomen of traction, and frequent micturition, urgent micturition, dysurea, urine color contamination are turbid, and even in urine, blood or sandstone being arranged is main clinical manifestation.Urinary system calculus can cause injury of urinary tract, block, and accompanying infection causes impaired renal function, so in case check that finding to suffer from the urinary system calculus should in time treat.
For the urinary system calculus, the Therapeutic Method of doctor trained in Western medicine is that microlith (diameter is below 0.5 centimetre) employing drinks more water, and relies on health self function to wait for calculus, and the method makes the patient very passive, in waiting for the calculus removing process, the patient still will stand ailing torment; Maximum size adopts operative treatment, namely by lithotomy, extracorporeal shock wave and cystolithic explosion therapy under endoscope (as renal pelvis mirror, ureteroscope) etc., though effect is good, but surgery cost is higher, and in the rubble discharge process, may cause renal colic, cause extra body burden to the patient.
in the technology of existing Chinese medicine field treatment urinary system calculus, Chinese invention patent application CN02153898.0 discloses a kind of name on May 28th, 2003 and has been called " a kind of Chinese medicine preparation for the treatment of urinary system calculus and preparation method thereof ", it is take the Chinese medicine semen juglandis as raw material, fuel-displaced through squeezing, the alcohol extraction precipitate with ethanol, the techniques such as spray drying obtain semen juglandis oil and semen juglandis extract dry powder, both measure mix homogeneously more by a certain percentage, make the dosage form that is fit to take with the active constituents of medicine of mixture, this invention formula is simple, only has Semen Juglandis raw material simply, can't accomplish the urinary system calculus of different parts is carried out the purpose of Coryza Treated by Syndrome Differentiation, and the operation trouble is refined in processing, cost is higher.
Summary of the invention
For existing treatment present situation, one of purpose of the present invention is to provide a kind of Chinese medicine composition for the treatment of the urinary system calculus, have easy to operate, evident in efficacy, sufferer and bear painful little characteristics, and its adopts comparatively common in the localities Chinese crude drug as raw material, with low cost.
Another object of the present invention just is to provide the preparation method of above-mentioned treatment urinary system calculus Chinese medicine composition.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind of Chinese medicine composition for the treatment of the urinary system calculus, preferred scheme is taken off the primary raw material of stating weight proportion and is prepared from: Herba Dianthi 9-15 part, Spora Lygodii 6-12 part, Poria 10-15 part, Rhizoma Alismatis 5-10 part, Polyporus 6-12 part, Herba Lysimachiae 15-60 part, Semen Plantaginis 5-15 part, Radix Cyathulae 4.5-9 part, Myrrha 5-15 part (preferred, Myrrha 5.5-14.5 part).
A kind of Chinese medicine composition for the treatment of the urinary system calculus, preferred scheme, taking off the primary raw material of stating weight proportion is prepared from: Herba Dianthi 10-12 part, Spora Lygodii 7-10 part, Poria 11-14 part, Rhizoma Alismatis 6-9 part, Polyporus 9-11 part, Herba Lysimachiae 25-40 part, Semen Plantaginis 8-11 part, Radix Cyathulae 5-8 part, Myrrha 7-12 part.
A kind of Chinese medicine composition for the treatment of the urinary system calculus, best scheme is taken off the primary raw material of stating weight proportion and is prepared from: 10 parts of Herba Dianthis, 8 parts of Spora Lygodii, 12 parts, Poria, 8 parts of Rhizoma Alismatis, 10 parts of Polyporus, 30 parts of Herba Lysimachiaes, 10 parts of Semen Plantaginiss, 6.5 parts of Radix Cyathulaes, 10 parts of Myrrhas.
A kind of preparation method for the treatment of the Chinese medicine composition of urinary system calculus specifically has following steps to be prepared from:
1. with Herba Dianthi, Poria, Rhizoma Alismatis, Polyporus, Herba Lysimachiae, Radix Cyathulae, Myrrha is placed in cold water and soaked 20-40 minute;
2. with Spora Lygodii, Semen Plantaginis is placed in the close gauze of matter, the closing in tighten;
3. the medicated bag of wrapping tighten in will be is 2. put into soaked medical material intense fire and is fried open, and turns 20-40 at a simmer minute, leaches medicinal liquid;
4. recrement adds cold water not have medical material again, and intense fire is fried open, and 15-30 at a simmer minute, twice medicinal liquid mixing was this Chinese medicine composition.
1. the preparation method of above-mentioned Chinese medicine composition, preparation process soak 20-40 minute (preferred 25-35 minute, be more preferably 30 minutes) in cold water.
3. the preparation method of above-mentioned Chinese medicine composition, preparation process turn 20-40 at a simmer minute (preferred 25-35 minute, be more preferably 30 minutes).
The preparation method of above-mentioned Chinese medicine composition, preparation process 4. 15-30 at a simmer minute (preferred 15-25 minute, be more preferably 20 minutes).
Using method: reach best therapeutic effect for making the present invention, the medicinal liquid of a daily dose evenly is divided into two parts, and every day is in sooner or later taking in one hour after meal.
This Chinese medicine composition is remarkable to urinary system calculus effect, and the effect of pain relieving, diuresis is arranged.Spora Lygodii in the side, Myrrha all have the effect of pain relieving, can be at initial stage rapid recovery patient's the pain symptom of taking medicine, the patient there is adhere to the confidence for the treatment of; Herba Dianthi, Semen Plantaginis, Rhizoma Alismatis etc. all have the effect of diuresis, can impel the smooth and easy discharge fast of calculus, alleviate patient's health misery and burden.
The pharmacological effect of each crude drug is respectively:
Herba Dianthi: bitter in the mouth, cold in nature.Inducing diuresis for treating stranguria syndrome is arranged, and the effect that removing blood stasis stimulates the menstrual flow is mainly used in the symptoms such as pyretic stranguria, stranguria with blood, stranguria caused by urinary stone, urinary obstruction.
Spora Lygodii: sweet in the mouth, cold in nature.Clearing away heat-damp and promoting diuresis is arranged, and the effect for the treatment of stranguria pain relieving is mainly used in the symptoms such as pyretic stranguria, sand Stranguria, stranguria with blood, Urethra astringent pain.
Poria: sweet in the mouth, property is flat.The eliminating dampness by diuresis diuresis is arranged, and calm effect is mainly used in the symptoms such as dysuria, insufficiency of the spleen lack of appetite, and its property of medicine is gentle, diuretic and do not hinder healthy energy.
Rhizoma Alismatis: sweet in the mouth, cold in nature.Promoting diuresis to eliminate damp pathogen is arranged, and the treating stranguria effect that expels the heat-evil is mainly used in dysuria, the symptoms such as the puckery pain of pyretic stranguria.
Polyporus: sweet in the mouth, property is flat.The effect of promoting diuresis to eliminate damp pathogen is arranged, be mainly used in dysuria.
Herba Lysimachiae: sweet in the mouth, cool in nature.Relieving stranguria by diuresis is arranged, heat-clearing and toxic substances removing, the effect of dissipating blood stasis for subsidence of swelling is mainly used in the symptoms such as liver and gall and urinary system calculus, pyretic stranguria, oedema due to nephritis.
Semen Plantaginis: sweet in the mouth, cold nature.Clearing away heat and promoting diuresis is arranged, and the effect of eliminating dampness by diuresis antidiarrheal is mainly used in dysuria, the inferior symptom of stranguria with turbid discharge band.
Radix Cyathulae: sweet in the mouth, property is flat.Eliminating blood stasis and inducing menstruation is arranged, inducing diuresis for treating stranguria syndrome, the effect of easing joint movement is mainly used in the symptoms such as hematuria stranguria with blood.
Myrrha: bitter in the mouth, property is flat.Another name myrrh " detailed outline ", bright Myrrha " national Chinese herbal medicine compilation ", Myrrha, myrrh are Chinese olive tree section plant Herba Violae tree, Ha Didingshu, the oleo-gum-resin that trunk section oozes out.Loose blood blood stasis removing is arranged, the effect of subduing swelling and relieving pain, Compendium of Material Medica record: the Myrrha blood that fall apart, energy alleviating pain and detumescence, granulation promoting.
Chinese medicine composition of the present invention is debated the principle of disease treatment based on Chinese medicine.The medical material of selecting is useful on table disease pain relieving, diuresis, also is useful on inner disease heat extraction and transfers kidney, takes into account inside and outside belonging to and medicine safely and effectively.The urinary system calculus there is fabulous therapeutical effect.
The specific embodiment
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1
Herba Dianthi 9 grams, Spora Lygodii 6 grams, Poria 10 grams, Rhizoma Alismatis 5 grams, Polyporus 6 grams, Herba Lysimachiae 15 grams, Semen Plantaginis 5 grams, Radix Cyathulae 4.5 grams, Myrrha 5 grams.
1. with Herba Dianthi, Poria, Rhizoma Alismatis, Polyporus, Herba Lysimachiae, Radix Cyathulae, Myrrha is placed in cold water and soaked 20 minutes;
2. with Spora Lygodii, Semen Plantaginis is placed in the close gauze of matter, the closing in tighten;
3. the medicated bag of wrapping tighten in will be is 2. put into soaked medical material intense fire and is fried open, and turns 20 minutes at a simmer, leaches medicinal liquid;
4. recrement adds cold water not have medical material again, and intense fire is fried open, and 15 minutes at a simmer, twice medicinal liquid mixing was this Chinese medicine composition.
Embodiment 2
Herba Dianthi 10 grams, Spora Lygodii 7 grams, Poria 11 grams, Rhizoma Alismatis 6 grams, Polyporus 9 grams, Herba Lysimachiae 25 grams, Semen Plantaginis 8 grams, Radix Cyathulae 5 grams, Myrrha 7 grams.
1. with Herba Dianthi, Poria, Rhizoma Alismatis, Polyporus, Herba Lysimachiae, Radix Cyathulae, Myrrha is placed in cold water and soaked 25 minutes;
2. with Spora Lygodii, Semen Plantaginis is placed in the close gauze of matter, the closing in tighten;
3. the medicated bag of wrapping tighten in will be is 2. put into soaked medical material intense fire and is fried open, and turns 25 minutes at a simmer, leaches medicinal liquid;
4. recrement adds cold water not have medical material again, and intense fire is fried open, and 15 minutes at a simmer, twice medicinal liquid mixing was this Chinese medicine composition.
Embodiment 3
Herba Dianthi 12 grams, Spora Lygodii 10 grams, Poria 14 grams, Rhizoma Alismatis 9 grams, Polyporus 11 grams, Herba Lysimachiae 40 grams, Semen Plantaginis 11 grams, Radix Cyathulae 8 grams, Myrrha 12 grams.
1. with Herba Dianthi, Poria, Rhizoma Alismatis, Polyporus, Herba Lysimachiae, Radix Cyathulae, Myrrha is placed in cold water and soaked 35 minutes;
2. with Spora Lygodii, Semen Plantaginis is placed in the close gauze of matter, the closing in tighten;
3. the medicated bag of wrapping tighten in will be is 2. put into soaked medical material intense fire and is fried open, and turns 35 minutes at a simmer, leaches medicinal liquid;
4. recrement adds cold water not have medical material again, and intense fire is fried open, and 25 minutes at a simmer, twice medicinal liquid mixing was this Chinese medicine composition.
Embodiment 4
Herba Dianthi 15 grams, Spora Lygodii 12 grams, Poria 15 grams, Rhizoma Alismatis 10 grams, Polyporus 12 grams, Herba Lysimachiae 60 grams, Semen Plantaginis 15 grams, Radix Cyathulae 9 grams, Myrrha 15 grams.
1. with Herba Dianthi, Poria, Rhizoma Alismatis, Polyporus, Herba Lysimachiae, Radix Cyathulae, Myrrha is placed in cold water and soaked 40 minutes;
2. with Spora Lygodii, Semen Plantaginis is placed in the close gauze of matter, the closing in tighten;
3. the medicated bag of wrapping tighten in will be is 2. put into soaked medical material intense fire and is fried open, and turns 40 minutes at a simmer, leaches medicinal liquid;
4. recrement adds cold water not have medical material again, and intense fire is fried open, and 30 minutes at a simmer, twice medicinal liquid mixing was this Chinese medicine composition.
Embodiment 5
Herba Dianthi 10 grams, Spora Lygodii 8 grams, Poria 12 grams, Rhizoma Alismatis 8 grams, Polyporus 10 grams, Herba Lysimachiae 30 grams, Semen Plantaginis 10 grams, Radix Cyathulae 6.5 grams, Myrrha 10 grams.
1. with Herba Dianthi, Poria, Rhizoma Alismatis, Polyporus, Herba Lysimachiae, Radix Cyathulae, Myrrha is placed in cold water and soaked 30 minutes;
2. with Spora Lygodii, Semen Plantaginis is placed in the close gauze of matter, the closing in tighten;
3. the medicated bag of wrapping tighten in will be is 2. put into soaked medical material intense fire and is fried open, and turns 30 minutes at a simmer, leaches medicinal liquid;
4. recrement adds cold water not have medical material again, and intense fire is fried open, and 20 minutes at a simmer, twice medicinal liquid mixing was this Chinese medicine composition.
Using method: reach best therapeutic effect for making the present invention, the medicinal liquid of a daily dose evenly is divided into two parts, and every day is in sooner or later taking in one hour after meal.
Model case one
What XX, man, 32 years old, Xuecheng District sand furrow town, Zaozhuang City, Shandong Province.Symptom: the right side lumbago, the symptoms such as frequent micturition, dysurea once appearred before January, and with the hematuria symptom.Hospital diagnosis is that sinus renalis closely has the strong echo hot spot of 0.3*0.4cm in the middle part.Sick age: 3 months.Examine the time: on October 15th, 2011; Use Chinese medicine composition of the present invention, took 2 days, urine is smooth and easy a lot, and pain alleviates to some extent; Took for 2 weeks, calculus is discharged; Consolidated for 2 weeks, drug withdrawal is so far without recurrence.
Model case two
Liu XX, female, 39 years old, Li Que town, Guangrao County, Dongying city.Symptom: right side abdomen pain, be angor, dripping sweat during outbreak, pain is radiated to the homonymy groin, and the symptom of urgent micturition, dysurea occurs.Sick age: 3 years.Examine the time: on April 20th, 2011; Use Chinese medicine composition of the present invention, take a week, urgent micturition, dysurea remission, right side abdomen pain greatly takes a turn for the better; Taking had the fritter calculus to discharge in 1 month; After taking 2 months, remove examination in hospital, calculus is discharged fully, and drug withdrawal is not recurrence so far.
Model case three
Lee XX, man, 60 years old, Shijingshan District, Beijing.Symptom: dysuria appears repeatedly, urine retention, inferior belly gas pain goes to hospital through B ultrasonic, x-ray inspection, and cystoscopy finds to have calculus 0.7*0.6cm, carries out the lithotripsy in treatment recovery from illness in hospital and leaves hospital, recurrence later six months of leaving hospital.Sick age: 2 years.Examine the time: on August 9th, 2011; Use Chinese medicine composition of the present invention, took 5 days, the dysuria symptom takes a turn for the better, and inferior belly gas pain alleviates; Take 1 first quarter moon, during have the fritter calculus to discharge with urine, the urine normal; Took 3 months, and went the examination in hospital calculus to discharge fully; The minimizing dose is taken and is continued to strengthen 15 days, and drug withdrawal is recurrence so far.
In order to verify the effect of Chinese medicine composition of the present invention, we have carried out on a large scale, the drug study (embodiment 5) of many person-times.Concrete experimental result such as following table:
Table 1:
Prove through clinical trial, for the calculus below diameter 0.5cm, Chinese medicine composition of the present invention is compared to traditional drinking-water calculus method, and effective percentage exceeds 59%, and the calculus time is shorter than drinking-water calculus method, and curative effect is more quick; For the calculus more than diameter 0.5cm, Chinese medicine composition of the present invention is compared to the shock wave lithotripsy method, and effective percentage exceeds 3%, and has no side effect in therapeutic process, and expense is cheap, and relapse rate is extremely low, is the safe and efficient medicine for the treatment of urinary system calculus.
The application's prescription is the distinguished veteran doctors of TCM proved recipe, has the prospect of industrialized implementation.Completing of this invention has benefited from Shandong Province's 12 Planning emphasis subjects---the support of Law of Economy subject fund.
It should be noted that at last, embodiment is the specific embodiment of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment, the present invention is had been described in detail, for a person skilled in the art, it still can be modified to the technical scheme that aforementioned each embodiment puts down in writing, and perhaps part technical characterictic wherein is equal to replacement.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (7)
1. Chinese medicine composition for the treatment of the urinary system calculus, it is characterized in that, taking off the primary raw material of stating weight proportion is prepared from: Herba Dianthi 9-15 part, Spora Lygodii 6-12 part, Poria 10-15 part, Rhizoma Alismatis 5-10 part, Polyporus 6-12 part, Herba Lysimachiae 15-60 part, Semen Plantaginis 5-15 part, Radix Cyathulae 4.5-9 part, Myrrha 5-15 part.
2. Chinese medicine composition according to claim 1, it is characterized in that, taking off the primary raw material of stating weight proportion is prepared from: Herba Dianthi 10-12 part, Spora Lygodii 7-10 part, Poria 11-14 part, Rhizoma Alismatis 6-9 part, Polyporus 9-11 part, Herba Lysimachiae 25-40 part, Semen Plantaginis 8-11 part, Radix Cyathulae 5-8 part, Myrrha 7-12 part.
3. Chinese medicine composition according to claim 1, is characterized in that, takes off the primary raw material of stating weight proportion and be prepared from: 11 parts of Herba Dianthis, 8 parts of Spora Lygodii, 12 parts, Poria, 8 parts of Rhizoma Alismatis, 10 parts of Polyporus, 30 parts of Herba Lysimachiaes, 10 parts of Semen Plantaginiss, 6.5 parts of Radix Cyathulaes, 10 parts of Myrrhas.
4. the preparation method of according to claim 1-3 arbitrary described Chinese medicine compositions is characterized in that preparation flow is:
1. with Herba Dianthi, Poria, Rhizoma Alismatis, Polyporus, Herba Lysimachiae, Radix Cyathulae, Myrrha is placed in cold water and soaked 20-40 minute;
2. with Spora Lygodii, Semen Plantaginis is placed in the close gauze of matter, the closing in tighten;
3. the medicated bag of wrapping tighten in will be is 2. put into soaked medical material intense fire and is fried open, and turns 20-40 at a simmer minute, leaches medicinal liquid;
4. recrement adds cold water not have medical material again, and intense fire is fried open, and 15-30 at a simmer minute, twice medicinal liquid mixing was this Chinese medicine composition.
5. the preparation method of Chinese medicine composition according to claim 4, is characterized in that, 1. preparation process soaks 20-40 minute (preferred 25-35 minute, be more preferably 30 minutes) in cold water.
6. the preparation method of Chinese medicine composition according to claim 4, is characterized in that, 3. preparation process turns 20-40 at a simmer minute (preferred 25-35 minute, be more preferably 30 minutes).
7. the preparation method of Chinese medicine composition according to claim 4, is characterized in that, preparation process 4. 15-30 at a simmer minute (preferred 15-25 minute, be more preferably 20 minutes).
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Cited By (3)
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| CN103285355A (en) * | 2013-06-14 | 2013-09-11 | 孟凡美 | Medicine for treating calculi in urinary system |
| CN104435339A (en) * | 2014-08-07 | 2015-03-25 | 于安仲 | Kidney-tonifying and calculus-removing compound preparation for urinary system and preparation method thereof |
| CN104491534A (en) * | 2014-12-15 | 2015-04-08 | 黄平县中科科技有限责任公司 | Traditional Chinese medicine for treating kidney stones |
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| CN104173633A (en) * | 2014-09-10 | 2014-12-03 | 苏黎 | Traditional Chinese medicine composition for treating urinary calculus and preparation method thereof |
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| CN103110763B (en) | 2014-08-20 |
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