CN103110763B - Traditional Chinese medicine composition for treating urinary calculus and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating urinary calculus and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating urinary calculus and a preparation method thereof. The traditional Chinese medicine composition mainly consists of dianthus superbus, Japanese climbing fern spore, Indian buead, alisma plantagoaquatica, agaric, longhairy antenoron herb, plantain seed, medicinal cyathula root and myrrh. The traditional Chinese medicine composition has the effects of inducing diuresis for treating strangurtia, clearing damp and promoting diuresis, has the effect of well treating pain, dark urine and difficulty of urination caused by urinary calculus, the urinary calculus can be effectively and rapidly treated, and the traditional Chinese medicine composition is an ideal and safe medicine for treating the urinary calculus.
Description
Technical field
The invention discloses a kind of Chinese medicine composition, especially treat Chinese medicine composition of urinary system calculus and preparation method thereof.Belong to Chinese medicine field.
Background technology
Urinary system calculus claims again lithangiuria, urinary calculus, is the commonly encountered diseases of urinary system.Refer at urinary system endogenous cause of ill urine concentrating and precipitating and form granule or in bulk sample aggregation; for urinary system commonly encountered diseases, be apt to occur in person between twenty and fifty, in recent years along with the continuous expansion of environmental pollution; the change of people's living habit, the patient of urinary system calculus is constantly increasing.
Urinary system calculus is the general name of kidney, ureter, bladder, calculus of urethra, and calculus is found in any position of kidney, bladder, ureter and urethra.By the position at lithangiuria place, be substantially divided into upper lithangiuria and calculus of lower urinary tract.Upper lithangiuria refers to kidney and ureteral calculus; Calculus of lower urinary tract comprises vesical calculus and calculus of urethra.The existence that the salt that forms calculus crystal in urine is saturation, suppress crystal formation material deficiency and nuclear matrix will form calculus, and stone composition has calcium oxalate, calcium phosphate and ammonium magnesium phosphate etc.
The pathogenesis of urinary system calculus is comparatively complicated, the traditional Chinese medical science thinks that the etiology and pathogenesis of urinary system calculus is that < < General Treatise on the Cause and Symptoms of Diseases > > carries: the impact of " Zhu Linzhe; therefore bladder is warm also by suffering from a deficiency of the kidney ", think that its etiology and pathogenesis is mainly the unable mistake of the functioning of bladder department that suffers from a deficiency of the kidney, damp-heat accumulation, decoct body fluid. with the passing of time the moon tires out, the poly-stone that forms.
Urinary system calculus is with the violent lumbago that occurs suddenly, the few abdomen of traction, and frequent micturition, urgent micturition, dysurea, urine color contamination are turbid, and even in urine, having blood or sandstone is main clinical manifestation.Urinary system calculus can cause injury of urinary tract, block, and accompanying infection causes impaired renal function, so once check that finding to suffer from urinary system calculus should treat in time.
For urinary system calculus, the Therapeutic Method of doctor trained in Western medicine is that microlith (diameter is below 0.5 centimetre) employing drinks more water, and relies on health self function to wait for calculus, and the method makes patient very passive, in waiting for calculus removing process, patient still will stand ailing torment; Maximum size adopts operative treatment, by lithotomy, extracorporeal shock wave and cystolithic explosion therapy under endoscope (as renal pelvis mirror, ureteroscope) etc., though effect is good, but surgery cost is higher, and in rubble discharge process, may cause renal colic, to patient, cause extra body burden.
In the technology of existing Chinese medicine field treatment urinary system calculus, Chinese invention patent application CN02153898.0 discloses a kind of name on May 28th, 2003 and has been called " a kind of Chinese medicine preparation for the treatment of urinary system calculus and preparation method thereof ", it is to take Chinese medicine semen juglandis as raw material, fuel-displaced through squeezing, alcohol extraction precipitate with ethanol, the techniques such as spraying is dry obtain semen juglandis oil and semen juglandis extract dry powder, both measure mix homogeneously more by a certain percentage, with the active constituents of medicine of mixture, make the dosage form that is applicable to taking, this invention formula is simple, only has Semen Juglandis raw material simply, cannot accomplish the urinary system calculus of different parts to carry out the object of Coryza Treated by Syndrome Differentiation, and operation trouble is refined in processing, cost is higher.
Summary of the invention
For existing treatment present situation, one of object of the present invention is to provide a kind of Chinese medicine composition for the treatment of urinary system calculus, there is easy to operate, evident in efficacy, sufferer and bear painful little feature, and its adopts comparatively common in the localities Chinese crude drug as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned treatment urinary system calculus Chinese medicine composition.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind of Chinese medicine composition for the treatment of urinary system calculus, preferred scheme, takes off the primary raw material of stating weight proportion and is prepared from: Herba Dianthi 9-15 part, Spora Lygodii 6-12 part, Poria 10-15 part, Rhizoma Alismatis 5-10 part, Polyporus 6-12 part, Herba Lysimachiae 15-60 part, Semen Plantaginis 5-15 part, Radix Cyathulae 4.5-9 part, Myrrha 5-15 part (preferred, Myrrha 5.5-14.5 part).
A kind of Chinese medicine composition for the treatment of urinary system calculus, preferred scheme, taking off the primary raw material of stating weight proportion is prepared from: Herba Dianthi 10-12 part, Spora Lygodii 7-10 part, Poria 11-14 part, Rhizoma Alismatis 6-9 part, Polyporus 9-11 part, Herba Lysimachiae 25-40 part, Semen Plantaginis 8-11 part, Radix Cyathulae 5-8 part, Myrrha 7-12 part.
Treat a Chinese medicine composition for urinary system calculus, best scheme, takes off the primary raw material of stating weight proportion and is prepared from: 10 parts of Herba Dianthis, 8 parts of Spora Lygodii, 12 parts, Poria, 8 parts of Rhizoma Alismatis, 10 parts of Polyporus, 30 parts of Herba Lysimachiaes, 10 parts of Semen Plantaginiss, 6.5 parts of Radix Cyathulaes, 10 parts of Myrrhas.
Treat a preparation method for the Chinese medicine composition of urinary system calculus, specifically have following steps to be prepared from:
1. by Herba Dianthi, Poria, Rhizoma Alismatis, Polyporus, Herba Lysimachiae, Radix Cyathulae, Myrrha is placed in cold water and soaks 20-40 minute;
2. by Spora Lygodii, Semen Plantaginis is placed in the close gauze of matter, closing in tighten;
3. the medicated bag of wrapping tighten in is 2. put into soaked medical material intense fire and be fried open, turn 20-40 minute at a simmer, leach medicinal liquid;
4. recrement adds cold water not have medical material again, and intense fire is fried open, 15-30 minute at a simmer, and twice medicinal liquid mixing is this Chinese medicine composition.
The preparation method of above-mentioned Chinese medicine composition, 1. preparation process soaks 20-40 minute (preferably 25-35 minute, is more preferably 30 minutes) in cold water.
The preparation method of above-mentioned Chinese medicine composition, 3. preparation process turns 20-40 at a simmer minute (preferably 25-35 minute, is more preferably 30 minutes).
The preparation method of above-mentioned Chinese medicine composition, preparation process 4. 15-30 at a simmer minute (preferably 15-25 minute, is more preferably 20 minutes).
Using method: for making the present invention reach best therapeutic effect, the medicinal liquid of a daily dose is evenly divided into two parts, every day is in sooner or later within one hour after meal, taking.
This Chinese medicine composition is remarkable to urinary system calculus effect, has the effect of pain relieving, diuresis.Spora Lygodii in side, Myrrha all have the effect of pain relieving, can be at initial stage rapid recovery patient's the pain symptom of taking medicine, and the confidence that patient is had adhere to treatment; Herba Dianthi, Semen Plantaginis, Rhizoma Alismatis etc. all have the effect of diuresis, can impel the smooth and easy discharge fast of calculus, alleviate patient's health misery and burden.
The pharmacological effect of each crude drug is respectively:
Herba Dianthi: bitter in the mouth, cold in nature.Have inducing diuresis for treating stranguria syndrome, the effect that removing blood stasis stimulates the menstrual flow, is mainly used in the symptoms such as pyretic stranguria, stranguria with blood, stranguria caused by urinary stone, urinary obstruction.
Spora Lygodii: sweet in the mouth, cold in nature.Have clearing away heat-damp and promoting diuresis, the effect for the treatment of stranguria pain relieving, is mainly used in the symptoms such as pyretic stranguria, sand Stranguria, stranguria with blood, Urethra astringent pain.
Poria: sweet in the mouth, property is flat.Have eliminating dampness by diuresis diuresis, calm effect, is mainly used in the symptoms such as dysuria, insufficiency of the spleen lack of appetite, and its property of medicine is gentle, diuretic and do not hinder healthy energy.
Rhizoma Alismatis: sweet in the mouth, cold in nature.Have promoting diuresis to eliminate damp pathogen, the treating stranguria effect that expels the heat-evil, is mainly used in dysuria, the symptoms such as the puckery pain of pyretic stranguria.
Polyporus: sweet in the mouth, property is flat.The effect that has promoting diuresis to eliminate damp pathogen, is mainly used in dysuria.
Herba Lysimachiae: sweet in the mouth, cool in nature.There is relieving stranguria by diuresis, heat-clearing and toxic substances removing, the effect of dissipating blood stasis for subsidence of swelling, is mainly used in the symptoms such as liver and gall and urinary system calculus, pyretic stranguria, oedema due to nephritis.
Semen Plantaginis: sweet in the mouth, cold nature.Have clearing away heat and promoting diuresis, the effect of eliminating dampness by diuresis antidiarrheal, is mainly used in dysuria, the inferior symptom of stranguria with turbid discharge band.
Radix Cyathulae: sweet in the mouth, property is flat.There is eliminating blood stasis and inducing menstruation, inducing diuresis for treating stranguria syndrome, the effect of easing joint movement, is mainly used in the symptoms such as hematuria stranguria with blood.
Myrrha: bitter in the mouth, property is flat.Another name myrrh < < detailed outline > >, bright Myrrha < < whole nation Chinese herbal medicine compilation > >, Myrrha, myrrh, for Chinese olive tree section plant Herba Violae tree, Ha Didingshu, the oleo-gum-resin that trunk portion oozes out.There is loose blood blood stasis removing, the effect of subduing swelling and relieving pain, < < Compendium of Materia Medica > > records: the Myrrha blood that fall apart, energy alleviating pain and detumescence, granulation promoting.
Chinese medicine composition of the present invention is debated the principle of disease treatment based on Chinese medicine.The medical material of selecting is useful on table disease pain relieving, diuresis, is also useful on inner disease heat extraction and adjusts kidney, takes into account and medicine safely and effectively inside and outside belonging to.Urinary system calculus is had to fabulous therapeutical effect.
The specific embodiment
Below in conjunction with embodiment and experimental example, describe technical scheme of the present invention in detail, but protection domain is not by this restriction.
embodiment 1
9 grams of Herba Dianthis, 6 grams of Spora Lygodii, 10 grams, Poria, 5 grams of Rhizoma Alismatis, 6 grams of Polyporus, 15 grams of Herba Lysimachiaes, 5 grams of Semen Plantaginiss, 4.5 grams of Radix Cyathulaes, 5 grams of Myrrhas.
1. by Herba Dianthi, Poria, Rhizoma Alismatis, Polyporus, Herba Lysimachiae, Radix Cyathulae, Myrrha is placed in cold water and soaks 20 minutes;
2. by Spora Lygodii, Semen Plantaginis is placed in the close gauze of matter, closing in tighten;
3. the medicated bag of wrapping tighten in is 2. put into soaked medical material intense fire and be fried open, turn 20 minutes at a simmer, leach medicinal liquid;
4. recrement adds cold water not have medical material again, and intense fire is fried open, and 15 minutes at a simmer, twice medicinal liquid mixing was this Chinese medicine composition.
embodiment 2
10 grams of Herba Dianthis, 7 grams of Spora Lygodii, 11 grams, Poria, 6 grams of Rhizoma Alismatis, 9 grams of Polyporus, 25 grams of Herba Lysimachiaes, 8 grams of Semen Plantaginiss, 5 grams of Radix Cyathulaes, 7 grams of Myrrhas.
1. by Herba Dianthi, Poria, Rhizoma Alismatis, Polyporus, Herba Lysimachiae, Radix Cyathulae, Myrrha is placed in cold water and soaks 25 minutes;
2. by Spora Lygodii, Semen Plantaginis is placed in the close gauze of matter, closing in tighten;
3. the medicated bag of wrapping tighten in is 2. put into soaked medical material intense fire and be fried open, turn 25 minutes at a simmer, leach medicinal liquid;
4. recrement adds cold water not have medical material again, and intense fire is fried open, and 15 minutes at a simmer, twice medicinal liquid mixing was this Chinese medicine composition.
embodiment 3
12 grams of Herba Dianthis, 10 grams of Spora Lygodii, 14 grams, Poria, 9 grams of Rhizoma Alismatis, 11 grams of Polyporus, 40 grams of Herba Lysimachiaes, 11 grams of Semen Plantaginiss, 8 grams of Radix Cyathulaes, 12 grams of Myrrhas.
1. by Herba Dianthi, Poria, Rhizoma Alismatis, Polyporus, Herba Lysimachiae, Radix Cyathulae, Myrrha is placed in cold water and soaks 35 minutes;
2. by Spora Lygodii, Semen Plantaginis is placed in the close gauze of matter, closing in tighten;
3. the medicated bag of wrapping tighten in is 2. put into soaked medical material intense fire and be fried open, turn 35 minutes at a simmer, leach medicinal liquid;
4. recrement adds cold water not have medical material again, and intense fire is fried open, and 25 minutes at a simmer, twice medicinal liquid mixing was this Chinese medicine composition.
embodiment 4
15 grams of Herba Dianthis, 12 grams of Spora Lygodii, 15 grams, Poria, 10 grams of Rhizoma Alismatis, 12 grams of Polyporus, 60 grams of Herba Lysimachiaes, 15 grams of Semen Plantaginiss, 9 grams of Radix Cyathulaes, 15 grams of Myrrhas.
1. by Herba Dianthi, Poria, Rhizoma Alismatis, Polyporus, Herba Lysimachiae, Radix Cyathulae, Myrrha is placed in cold water and soaks 40 minutes;
2. by Spora Lygodii, Semen Plantaginis is placed in the close gauze of matter, closing in tighten;
3. the medicated bag of wrapping tighten in is 2. put into soaked medical material intense fire and be fried open, turn 40 minutes at a simmer, leach medicinal liquid;
4. recrement adds cold water not have medical material again, and intense fire is fried open, and 30 minutes at a simmer, twice medicinal liquid mixing was this Chinese medicine composition.
embodiment 5
10 grams of Herba Dianthis, 8 grams of Spora Lygodii, 12 grams, Poria, 8 grams of Rhizoma Alismatis, 10 grams of Polyporus, 30 grams of Herba Lysimachiaes, 10 grams of Semen Plantaginiss, 6.5 grams of Radix Cyathulaes, 10 grams of Myrrhas.
1. by Herba Dianthi, Poria, Rhizoma Alismatis, Polyporus, Herba Lysimachiae, Radix Cyathulae, Myrrha is placed in cold water and soaks 30 minutes;
2. by Spora Lygodii, Semen Plantaginis is placed in the close gauze of matter, closing in tighten;
3. the medicated bag of wrapping tighten in is 2. put into soaked medical material intense fire and be fried open, turn 30 minutes at a simmer, leach medicinal liquid;
4. recrement adds cold water not have medical material again, and intense fire is fried open, and 20 minutes at a simmer, twice medicinal liquid mixing was this Chinese medicine composition.
Using method: for making the present invention reach best therapeutic effect, the medicinal liquid of a daily dose is evenly divided into two parts, every day is in sooner or later within one hour after meal, taking.
model case one
What XX, man, 32 years old, sand furrow town, Xuecheng District, Zaozhuang City, Shandong Province.Symptom: right side lumbago, before January, once there is the symptoms such as frequent micturition, dysurea, and with hematuria symptom.Hospital diagnosis is that the nearly middle part of sinus renalis has the strong echo hot spot of 0.3*0.4cm.Sick age: 3 months.Examine the time: on October 15th, 2011; Use Chinese medicine composition of the present invention, take 2 days, urine is smooth and easy a lot, and pain alleviates to some extent; Take 2 weeks, calculus is discharged; Consolidate 2 weeks, drug withdrawal is so far without recurrence.
model case two
Liu XX, female, 39 years old, Li Que town, Guangrao County, Dongying city.Symptom: right side abdomen pain is angor, dripping sweat during outbreak, pain is radiated to homonymy groin, and occurs the symptom of urgent micturition, dysurea.Sick age: 3 years.Examine the time: on April 20th, 2011; Use Chinese medicine composition of the present invention, take one week, urgent micturition, dysurea remission, right side abdomen pain greatly takes a turn for the better; Take and within 1 month, have fritter calculus to discharge; Take after 2 months, remove examination in hospital, calculus is discharged completely, and drug withdrawal is not recurrence so far.
model case three
Lee XX, man, 60 years old, Shijingshan District, Beijing.Symptom: repeatedly there is dysuria, urine retention, inferior belly gas pain, goes to hospital through B ultrasonic, x-ray inspection, and cystoscopy, finds that there is calculus 0.7*0.6cm, carries out lithotripsy in treatment recovery from illness and leaves hospital, recurrence later six months of leaving hospital in hospital.Sick age: 2 years.Examine the time: on August 9th, 2011; Use Chinese medicine composition of the present invention, take 5 days, dysuria symptom takes a turn for the better, and inferior belly gas pain alleviates; Take 1 first quarter moon, during have fritter calculus to discharge with urine, urine normal; Take 3 months, go examination in hospital calculus to discharge completely; Minimizing dose is taken and is continued to strengthen 15 days, and drug withdrawal is recurrence so far.
In order to verify the effect of Chinese medicine composition of the present invention, we have carried out on a large scale, the drug study (embodiment 5) of many person-times.Specific experiment result is as following table:
Table 1:
Through clinical trial, prove, for the calculus below diameter 0.5cm, Chinese medicine composition of the present invention is compared to traditional drinking-water calculus method, and effective percentage exceeds 59%, and the calculus time is shorter than drinking-water calculus method, and curative effect is more quick; For calculus more than diameter 0.5cm, Chinese medicine composition of the present invention is compared to shock wave lithotripsy method, and effective percentage exceeds 3%, and has no side effect in therapeutic process, and expense is cheap, and relapse rate is extremely low, is the safe and efficient medicine for the treatment of urinary system calculus.
The application's prescription is distinguished veteran doctors of TCM proved recipe, has the prospect of industrialized implementation.Completing of this invention has benefited from Shandong Province's 12 Planning emphasis subjects---the support of Law of Economy subject fund.
Finally it should be noted that, embodiment is the specific embodiment of optimum of the present invention, be not limited to the present invention, although the present invention is had been described in detail with reference to previous embodiment, for a person skilled in the art, its technical scheme that still can record aforementioned each embodiment is modified, or part technical characterictic is wherein equal to replacement.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (9)
1. a preparation method for the treatment of the Chinese medicine composition of urinary system calculus, it is characterized in that, take off the raw material of stating weight proportion and be prepared from: Herba Dianthi 9-15 part, Spora Lygodii 6-12 part, Poria 10-15 part, Rhizoma Alismatis 5-10 part, Polyporus 6-12 part, Herba Lysimachiae 15-60 part, Semen Plantaginis 5-15 part, Radix Cyathulae 4.5-9 part, Myrrha 5-15 part, step is as follows;
1. by Herba Dianthi, Poria, Rhizoma Alismatis, Polyporus, Herba Lysimachiae, Radix Cyathulae, Myrrha is placed in cold water and soaks 20-40 minute;
2. by Spora Lygodii, Semen Plantaginis is placed in the close gauze of matter, closing in tighten;
3. the medicated bag of wrapping tighten in is 2. put into soaked medical material intense fire and be fried open, turn 20-40 minute at a simmer, leach medicinal liquid;
4. recrement adds cold water not have medical material again, and intense fire is fried open, 15-30 minute at a simmer, and twice medicinal liquid mixing is this Chinese medicine composition.
2. preparation method according to claim 1, is characterized in that, each crude drug is as follows: Herba Dianthi 10-12 part, Spora Lygodii 7-10 part, Poria 11-14 part, Rhizoma Alismatis 6-9 part, Polyporus 9-11 part, Herba Lysimachiae 25-40 part, Semen Plantaginis 8-11 part, Radix Cyathulae 5-8 part, Myrrha 7-12 part.
3. preparation method according to claim 1, is characterized in that, each crude drug is as follows: 11 parts of Herba Dianthis, 8 parts of Spora Lygodii, 12 parts, Poria, 8 parts of Rhizoma Alismatis, 10 parts of Polyporus, 30 parts of Herba Lysimachiaes, 10 parts of Semen Plantaginiss, 6.5 parts of Radix Cyathulaes, 10 parts of Myrrhas.
4. preparation method according to claim 1, is characterized in that, 1. preparation process soaks 25-35 minute in cold water.
5. preparation method according to claim 4, is characterized in that, 1. preparation process soaks 30 minutes in cold water.
6. preparation method according to claim 1, is characterized in that, 3. preparation process turns 25-35 minute at a simmer.
7. preparation method according to claim 6, is characterized in that, 3. preparation process turns 30 minutes at a simmer.
8. preparation method according to claim 1, is characterized in that, preparation process is 15-25 minute at a simmer 4..
9. preparation method according to claim 8, is characterized in that, preparation process 4. 20 minutes at a simmer.
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| CN104435339A (en) * | 2014-08-07 | 2015-03-25 | 于安仲 | Kidney-tonifying and calculus-removing compound preparation for urinary system and preparation method thereof |
| CN104491534B (en) * | 2014-12-15 | 2017-10-31 | 黄平县中科科技有限责任公司 | A kind of Chinese medicine for treating kidney stone |
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