CN103070977B - Traditional Chinese medicine composition for treating bone diseases and preparation of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for treating bone diseases and preparation of traditional Chinese medicine composition Download PDFInfo
- Publication number
- CN103070977B CN103070977B CN201310051118.2A CN201310051118A CN103070977B CN 103070977 B CN103070977 B CN 103070977B CN 201310051118 A CN201310051118 A CN 201310051118A CN 103070977 B CN103070977 B CN 103070977B
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- medicine composition
- traditional chinese
- parts
- gram
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Abstract
The invention belongs to the field of traditional Chinese medicine compound. Particularly, the invention relates to a traditional Chinese medicine composition for treating bone diseases and a preparation of the traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating arthritis and a preparation of the traditional Chinese medicine composition. The traditional Chinese medicine composition provided by the invention mainly consists of the following ingredients in parts by weight: 5 to 20 parts of folium artemisiae argyi, 5 to 20 parts of garden balsam stem, 5 to 20 parts of lycopodium clavatum, 5 to 20 parts of safflower, 5 to 15 parts of pseudo-ginseng, 1 to 10 parts of eucommia ulmoides and 1 to 10 parts of hot pepper. Compared with the prior art, the traditional Chinese medicine composition provided by the invention starts from the important reason for causing the bone diseases, fundamentally solves the problems of bone disease patients through promoting qi to activate blood and relaxing tendons and collaterals, has obvious treatment effects and has the advantages that the ingredients are simple, the side effects are small, the treatment course is short, and the like.
Description
Technical field
The invention belongs to Chinese medicine compound field, specifically, relate to a kind of Chinese prescription and the preparation thereof that are used for the treatment of osteopathia, especially relate to one and be used for the treatment of arthritic Chinese prescription and preparation thereof.
Background technology
After the poison such as wind, cold, wet, heat evil invasion and attack collaterals of human, osteoarthrosis, can cause that human qi and blood running is smooth, meridians are inaccessible obstructed, cause the hazardous material deposition such as vivotoxin, blood rubbish at joint part, crystallization forms the complex of surface for differential protein, this complex can to joint, organize and constantly corrode, destroy, and block nerves is conducted, is blocked and organize nutrient to carry, and excite immune attack in body, cause affected joints inflammatory reaction, occur a series of pathological changes such as heating, pain, numbness, swelling, handicapped, tissue necrosis.When these pathological changes appear in human body, we are referred to as osteopathia.Osteopathia professional angle be " osteopathia ", it is one of orthopaedic disease three serious disease.Osteopathia generally comprises: rheumatic arthritis, rheumatoid arthritis, degenerative osteoarthritis, ankylosing spondylitis, gouty arthritis, cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis, hyperosteogeny, femur head necrosis, puerperal exposure to wind etc.Along with the change of life pattern, people are in air conditioner surroundings for a long time, are used to sitting, lack motion, a lot of people is with advancing age by showing various osteopathia, and especially various types of class joint is scorching, the crowd that more than 60 years old prevalences can reach more than 60%, 75 years old then reaches 80%.
At present, the treatment of osteopathia has multiple method.For acute symptoms such as pain, normal western medicine or the naturopathy of adopting relaxes, and fundamentally will eliminate these symptoms, and should set about from the cause of disease, relaxing muscles and tendons and activating QI and blood in the collateral, blood circulation promoting, at this moment Chinese medicine there has been only sky and obtains thick advantage.Such as, Chinese patent (CN102836177A) just discloses a kind of Chinese medicine preparation for the treatment of osteopathia, said preparation comprises two groups of medicament composing prescriptions, and first group is: Scolopendra, Scorpio, Bungarus Parvus, Zaocys, Pheretima, Squama Manis, Eupolyphaga Seu Steleophaga, Apis, Formica fusca, Moschus, Venenum Bufonis; Make plaster A.Second group is: Semen Strychni, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Flos Daturae, Radix Aconiti, Radix Aconiti Kusnezoffii, Cortex Cinnamomi, Radix Aconiti Lateralis Preparata, Radix Notoginseng, Rhizoma Chuanxiong, Radix Dipsaci, Radix Cyathulae, Fructus Psoraleae, Borneolum Syntheticum, Rhizoma Homalomenae, Radix Clematidis, Herba Ephedrae, Herba Asari, Rhizoma Sparganii, Rhizoma Curcumae, Radix Angelicae Sinensis, Flos Carthami, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Nidus Vespae, the Cortex Eucommiae, Semen Momordicae; Make plaster B.During use, plaster A and plaster B alternately sticks.Chinese patent (CN1631430) " a kind of Chinese medicinal ointment for the treatment of osteopathia " discloses a kind of Chinese medicinal ointment for the treatment of osteopathia, and this Chinese medicinal ointment contains the crude drug of following weight portion: Radix Saposhnikoviae, Cortex erythrinae, Limitation-or-qualification label grass, Rhizoma Et Radix Notopterygii, Rhizoma Cibotii, Herba Ephedrae, Flos Carthami are respectively 2-9 part; Herba Asari and each 0.5-4 part of Scolopendra; Camphora 0-1 part.But these prescriptions, many and assorted containing flavour of a drug, safety is wayward, and drug effect is slow, needs long-term continuing to use.
Summary of the invention
In order to solve the problems of the technologies described above, the invention provides that a kind of composition is simple, drug effect is fast, for Chinese prescription and the preparation thereof of bone disease treatment, especially a kind of for arthritic Chinese prescription and preparation thereof, this Chinese prescription is mainly made up of following raw material: Folium Artemisiae Argyi, Herba speranskiae tuberculatae, Herba Lycopodii, Flos Carthami, Radix Notoginseng, the Cortex Eucommiae, Fructus Capsici.
Chinese prescription of the present invention calculates by parts by weight of raw materials, primarily of Folium Artemisiae Argyi 5-20 part, Herba speranskiae tuberculatae 5-20 part, Herba Lycopodii 5-20 part, Flos Carthami 5-20 part, Radix Notoginseng 5-15 part, Cortex Eucommiae 1-10 part, Fructus Capsici 1-10 part composition, preferably by Folium Artemisiae Argyi 5-20 gram, Herba speranskiae tuberculatae 5-20 gram, Herba Lycopodii 5-20 gram, Flos Carthami 5-20 gram, Radix Notoginseng 5-15 gram, Cortex Eucommiae 1-10 gram, Fructus Capsici 1-10 gram form.
Chinese medicine composition of the present invention calculates by parts by weight of raw materials, also comprises Herba Urticae Cannabinae 3-15 part, Semen Citri Reticulatae 3-15 part, Bulbus Allii Macrostemonis 3-20 part, the preferred 3-15 of Herba Urticae Cannabinae gram, Semen Citri Reticulatae selects 3-15 gram, the preferred 3-20 gram of Bulbus Allii Macrostemonis.
Chinese medicine composition of the present invention is made up of raw extract, and described crude drug extract is that water extract gets thing or/and alcoholic solution extract.
Chinese medicine composition of the present invention is made up of raw extract, and described crude drug extract is that 8-10% salt water extract gets thing or/and the alcoholic solution extract of 60-75%.
Chinese medicine composition of the present invention can be made into external preparation, and described external preparation is the one in unguentum, patch, varnish.
Chinese medicine composition of the present invention can be made into oral formulations, and described oral formulations is granule.
Chinese medicine composition of the present invention can be used for the preparation for the treatment of osteopathia class medicine aspect, and described osteopathia is arthritis.
Compared with prior art, Chinese prescription of the present invention is started with from causing the first cause of osteopathia, passes through promoting flow of QI and blood, relaxing muscles and tendons and activating QI and blood in the collateral, fundamentally solve the problem of patient with bone disease, therapeutic effect is obvious, and has the advantages such as component is simple, side effect is little, short treating period.
Detailed description of the invention
Below in conjunction with specific embodiment, preparation method of the present invention is described further, but protection scope of the present invention is not limited to this.
The preparation of embodiment 1 varnish
Chinese prescription: Folium Artemisiae Argyi 20 grams, Herba speranskiae tuberculatae 20 grams, Herba Lycopodii 10 grams, 8 grams, Flos Carthami, Radix Notoginseng 8 grams, the Cortex Eucommiae 6 grams, 3 grams, Fructus Capsici.
Varnish adjuvant: PVA25g, glycerol 18ml, azone 8ml, 95% ethanol are about 90ml, deionized water.
Preparation: get crude drug, pulverizes, and crosses 60 mesh sieves, obtains medicinal powder, get medicinal powder, and 100 DEG C, the water adding 6 times amount extracts 2h, obtains extracting solution.Extracting solution is evaporated to about 45ml, filters, leaching filtrate.Get PVA25g, make it fully swelling with distilled water immersion 24h, then make it comparatively fast soluble in water in 90 DEG C of heating in water bath, filter, obtain uniform rubber cement, add medicinal substances extract filtrate and 18ml glycerol successively, constantly stir, separately get 8ml azone, add 95% ethanol 90ml dissolving slowly to add in above-mentioned rubber cement liquid, and constantly stir, separate out to prevent PVA.Finally be settled to 250ml with distilled water and namely obtain varnish.
The preparation of embodiment 2 patch
Chinese prescription: Folium Artemisiae Argyi 8 grams, Herba speranskiae tuberculatae 15 grams, Herba Lycopodii 15 grams, 6 grams, Flos Carthami, Radix Notoginseng 6 grams, the Cortex Eucommiae 5 grams, 3 grams, Fructus Capsici.
Patch adjuvant: azone 8ml, sodium lauryl sulphate 1g, glycerol 3g, glyceryl monostearate 15g, paraffin 15g, vaseline 3g, deionized water 15ml.
Preparation: get crude drug, pulverizes, and crosses 60 mesh sieves, obtains medicinal powder, get medicinal powder, adds the alcohol reflux 1 hour of 5 times amount 75%, obtains extracting solution.Herbal extract is evaporated to paste, add deionized water, water-soluble base glycerol and sodium lauryl sulphate, heating in water bath fusing evenly, then adds fat-soluble substrate azone, glyceryl monostearate, paraffin, vaseline, and heating in water bath fusing makes evenly, ultrasonic degas, being spread evenly across after slightly cold on cotton, natural airing, is 5cm × 60cm by trimming, be affixed on pressure sensitive adhesive, obtain patch.
The preparation of embodiment 3 unguentum
Chinese prescription: Folium Artemisiae Argyi 12 grams, Herba speranskiae tuberculatae 15 grams, Herba Lycopodii 15 grams, 6 grams, Flos Carthami, Radix Notoginseng 6 grams, the Cortex Eucommiae 5 grams, 3 grams, Fructus Capsici.
Unguentum adjuvant: stearic acid 20g, lanoline 6g, white vaseline 10g, liquid Paraffin 16ml, sodium lauryl sulphate 3g, ethyl hydroxybenzoate 0.4g, glycerol 12g, deionized water 300ml.
Preparation: get crude drug, pulverizes, and crosses 60 mesh sieves, obtains medicinal powder, get medicinal powder, adds the alcohol reflux 1 hour of 5 times amount 75%, obtains extracting solution.Extracting solution is evaporated to paste.Get medicinal substances extract thick paste and oil-phase component stearic acid, lanoline, white vaseline, liquid paraffin in evaporating dish, be placed in water-bath and be heated to 80 DEG C of mixed meltings; Separately water-phase component sodium lauryl sulphate, ethyl hydroxybenzoate, glycerol and deionized water are put in beaker, in water-bath, be also heated to about 80 DEG C; Under agitation add in oil-phase component by water-phase component with thread shape, water-bath continues keep constant temperature and be stirred to the semi-solid that is creamy white, then at room temperature continue to be stirred to condensation, obtain O/W type emulsion-type substrate, fill, obtains unguentum.
The preparation of embodiment 4 granule
Chinese prescription: Folium Artemisiae Argyi 10 grams, Herba speranskiae tuberculatae 15 grams, Herba Lycopodii 10 grams, 8 grams, Flos Carthami, Radix Notoginseng 8 grams, the Cortex Eucommiae 6 grams, 3 grams, Fructus Capsici, Herba Urticae Cannabinae 15 grams, Semen Citri Reticulatae 6 grams, Bulbus Allii Macrostemonis 10 grams.
Granule adjuvant: beta-schardinger dextrin-28g, CMC-Na0.9g, microcrystalline Cellulose 7g.
Preparation: get crude drug, pulverizes, and crosses 60 mesh sieves, obtains medicinal powder.Get the medicinal powder of Herba speranskiae tuberculatae, the Cortex Eucommiae, Herba Lycopodii and Herba Urticae Cannabinae, the saline 100 DEG C adding 10% of 6 times amount extracts 2h, filters.Filtrate is stand-by.Medicinal residues and other medicinal powder add the alcohol reflux 1 hour of 5 times amount 75%, leaching filtrate.Merge two extracting solution and be evaporated to paste, drying, pulverizing.Get CMC-Na, add the alcoholic solution 8ml heating for dissolving of 50%, stir evenly, obtain the CMC-Na solution of 10%.By medicinal substances extract powder and beta-schardinger dextrin-, microcrystalline Cellulose and CMC-Na solution, mixing, then the alcoholic solution mixing adding 10ml50%, make soft material.Get crushed 12 mesh sieves of soft material, make wet granular, dry 45min, obtain dry granule, arrange after 10 mesh sieves and 30 mesh sieves in 55 DEG C, packaging, obtains granule.
For compared with the prior art, the present invention adopts medicinal capsule for treating rheumatalgia to be reference substance, with the patient with bone disease of rheumatic arthritis, rheumatoid arthritis, gouty arthritis for investigating object, with cure rate (%) for index, observe the therapeutic effect of embodiment 1-4 product, the results are shown in following table:
| Group | Rheumatic arthritis (%) | Rheumatoid arthritis (%) | Gouty arthritis (%) |
| Embodiment 1 | 78 | 81 | 76 |
| Embodiment 2 | 82 | 80 | 84 |
| Embodiment 3 | 81 | 82 | 83 |
| Embodiment 4 | 88 | 89 | 86 |
| Reference substance | 68 | 72 | 71 |
As seen from the above table, the successful of the treatment osteopathia of embodiment of the present invention 1-4 product, compared with reference substance medicinal capsule for treating rheumatalgia, therapeutic effect will be got well.The therapeutic effect of embodiment 4 product and the therapeutic effect of reference substance are significant difference, are also better than embodiment 1,2 product, and this is relevant with its prescription composition and extracting method.
Claims (4)
1. one kind is used for the treatment of arthritic Chinese medicine composition, it is characterized in that, described Chinese medicine composition calculates by raw materials quality part, is made up of Folium Artemisiae Argyi 5-20 part, Herba speranskiae tuberculatae 5-20 part, Herba Lycopodii 5-20 part, Flos Carthami 5-20 part, Radix Notoginseng 5-15 part, Cortex Eucommiae 1-10 part, Fructus Capsici 1-10 part, Herba Urticae Cannabinae 3-15 part, Semen Citri Reticulatae 3-15 part, Bulbus Allii Macrostemonis 3-20 part.
2. Chinese medicine composition as claimed in claim 1, it is characterized in that, described Chinese medicine composition by Folium Artemisiae Argyi 5-20 gram, Herba speranskiae tuberculatae 5-20 gram, Herba Lycopodii 5-20 gram, Flos Carthami 5-20 gram, Radix Notoginseng 5-15 gram, Cortex Eucommiae 1-10 gram, Fructus Capsici 1-10 gram, Herba Urticae Cannabinae 3-15 gram, Semen Citri Reticulatae 3-15 gram, Bulbus Allii Macrostemonis 3-20 restrain into.
3. Chinese medicine composition as claimed in claim 2, it is characterized in that, described Chinese medicine composition makes external preparation, and described external preparation is the one in unguentum, patch, varnish.
4. Chinese medicine composition as claimed in claim 2, it is characterized in that, described Chinese medicine composition makes oral formulations, and described oral formulations is granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310051118.2A CN103070977B (en) | 2013-02-07 | 2013-02-07 | Traditional Chinese medicine composition for treating bone diseases and preparation of traditional Chinese medicine composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310051118.2A CN103070977B (en) | 2013-02-07 | 2013-02-07 | Traditional Chinese medicine composition for treating bone diseases and preparation of traditional Chinese medicine composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103070977A CN103070977A (en) | 2013-05-01 |
| CN103070977B true CN103070977B (en) | 2015-02-04 |
Family
ID=48147823
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310051118.2A Expired - Fee Related CN103070977B (en) | 2013-02-07 | 2013-02-07 | Traditional Chinese medicine composition for treating bone diseases and preparation of traditional Chinese medicine composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103070977B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103463173A (en) * | 2013-09-25 | 2013-12-25 | 崔永堂 | Healthcare bathing medicine and medicine liquid and preparation method thereof |
| CN109453293A (en) * | 2018-12-20 | 2019-03-12 | 叶晓薇 | A kind of the bathing powder and its application method of the dredging the channel that keeps fit and healthy |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20110017365A (en) * | 2008-05-30 | 2011-02-21 | 페어필드 클리니컬 트라이얼즈 엘엘씨 | Method and composition for skin inflammation and discoloration |
| CN101559089A (en) * | 2009-05-11 | 2009-10-21 | 杨继新 | Auxiliary treating method for lumbar intervertebral disc protrusion |
| CN102274252B (en) * | 2011-08-11 | 2012-10-03 | 张晋瑞 | Stauntonvine external applied preparation for treating rheumatoid diseases and preparation method thereof |
-
2013
- 2013-02-07 CN CN201310051118.2A patent/CN103070977B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN103070977A (en) | 2013-05-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100462097C (en) | Externally applied ointment for treating hyperosteogeny and preparation method thereof | |
| CN101224291B (en) | Plaster for treating breast nodules and preparing method thereof | |
| CN103156972B (en) | Traditional Chinese medicine combination for treating fracture, hairline fracture and traumatic injury | |
| CN100531773C (en) | Pain-relieving plaster and its preparation method | |
| CN101670078B (en) | External medicament for treating cervical osteoarthritis | |
| CN103768175B (en) | Medicine for treating protrusion of lumbar intervertebral disc and drug-separated moxibustion of medicine | |
| CN103251750B (en) | Externally applied medicinal oil for treating middle-aged and old-aged rheumatic diseases | |
| CN104353019A (en) | Traditional Chinese medicine hot compress bag with meridian dredging and internal organ conditioning functions and preparation method of traditional Chinese medicine hot compress bag | |
| CN101721529B (en) | Composition with functions of clearing heat and detoxicating and preparation method thereof | |
| CN103070977B (en) | Traditional Chinese medicine composition for treating bone diseases and preparation of traditional Chinese medicine composition | |
| CN103432551B (en) | Externally applied medicine for treating scapulohumeral periarthritis, radiohumeral bursitis and inexplicable ostalgia | |
| CN1252999A (en) | Exterior-applied Chinese-medicinal ointment for treating more intractable internal and surgical diseases | |
| CN101007160A (en) | Plaster for treating ostealgia and its preparation method | |
| CN102895620A (en) | Preparation technology and production method for integrated new formulation of licorice heart-draining decoction | |
| CN103083488B (en) | Traditional Chinese medical composition for treating bone disease as well as preparation thereof | |
| CN100534466C (en) | Preparation for treating arthritis and preparation method thereof | |
| CN103100010A (en) | Drug for treatment of rheumatic arthritis | |
| CN104435962A (en) | Pharmaceutical composition for treating dyspeptic diarrhea of piglets and preparation method thereof | |
| CN104491157A (en) | Traditional Chinese medicine composition for treating photosensitive skin diseases | |
| CN109718334A (en) | A kind of emplastrum production method for rheumatism bone disease and neck-shoulder pain, lumbago and leg pain | |
| CN103340972A (en) | Traditional Chinese medicine composition for treating traumatic injuries | |
| CN102631496B (en) | Traditional Chinese medicine composition capable of improving immunity and resisting fatigue | |
| CN106267134A (en) | A kind of anti-inflammatory analgesic Chinese medicine composition and preparation method thereof | |
| CN101991838A (en) | Medicinal composition for curing osteoproliferation, rheumatism, rheumatoid diseases and herniated disk | |
| CN105343705A (en) | Rheumatoid arthritis treatment medicine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150204 Termination date: 20160207 |