CN103768175B - Medicine for treating protrusion of lumbar intervertebral disc and drug-separated moxibustion of medicine - Google Patents
Medicine for treating protrusion of lumbar intervertebral disc and drug-separated moxibustion of medicine Download PDFInfo
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- CN103768175B CN103768175B CN201410019504.8A CN201410019504A CN103768175B CN 103768175 B CN103768175 B CN 103768175B CN 201410019504 A CN201410019504 A CN 201410019504A CN 103768175 B CN103768175 B CN 103768175B
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Abstract
The invention discloses a medicine for treating protrusion of lumbar intervertebral disc and a drug-separated moxibustion of the medicine. The medicine is prepared from the following components in percentage by weight: 13-16 parts of raw monkshood, 14-16 percent of raw kusnezoff monkshood root, 8-12 percent of frankincense, 9-12 percent of myrrh, 18-22 percent of angelica pubescens, 18-22 percent of radix clematidis, 3-6 percent of camphor, 4-6 percent of borneol. The drug-separated moxibustion comprises a pressure-sensitive adhesive applied non-woven fabric, a heating element, moxibustion plaster and release paper, wherein the breathable side of the heating element is adhered to the pressure-sensitive adhesive applied non-woven fabric; the moxibustion plaster is applied to the non-breathable side of the heating element; the release paper is adhered to the moxibustion plaster; the moxibustion plaster is prepared from the medicine for treating protrusion of lumbar intervertebral disc and auxiliary materials. According to the drug-separated moxibustion, moxibustion treatment and medical treatment are organically combined into a whole, heat, drug-physical and biochemical factors are matched and synergized to act on acupoints of human channels and collaterals, the endogenous exciting effect is reinforced, and the medical effect of the drug-separated moxibustion can be strengthened. Compared with a traditional moxa-burning drug-separated moxibustion, the drug-separated moxibustion is more reasonable, convenient and effective, and is applicable to industrial production.
Description
Technical field
The present invention relates to a kind of medicine and medical apparatus thereof for the treatment of prolapse of lumbar intervertebral disc, belong to the field of Chinese medicines; Particularly relate to a kind of medicine and herbs-partition moxibustion thereof for the treatment of prolapse of lumbar intervertebral disc.
Background technology
In recent years, prolapse of lumbar intervertebral disc has become a kind of popular frequently-occurring disease.The syndrome that prolapse of lumbar intervertebral disc is lumbar degenerative disc, Anular disruption, Nucleus pulposus, pressuring neural root, cauda equina nerve show.Prolapse of lumbar intervertebral disc great majority occur in lumbar vertebra 4-5 gap.Pathogenic factors: (1) age: middle age is in the majority; (2) sex: male has an attack of one's old illness rate higher than women; (3) occupation: heavy worker, lower back bear comparatively severe one susceptible disease; (4) environment: summer and autumn are overcast and rainy is subject to cold-damp, and rate of having an attack of one's old illness is high.The traditional Chinese medical science is thought, prolapse of lumbar intervertebral disc is deficiency in origin and marks reality.Be affected by the cold wet exopathogen person, and how real its card is, and how anxious morbidity is; Because of the caused person of kidney channel loss, how empty its card is, and morbidity is delayed more.According to tcm theory, generally primary disease is divided into lumbago due to cold-damp, lumbago due to damp-heat, lumbago due to blood stasis, lumbago due to renal deficiency four class and give dialectical treating, but usually has simulataneous insufficiency and excessive, card marquis is complicated, therefore with kidney asthenia as the principal aspect, eliminating evil is mark, can control effectively.
Clinical manifestation: (1) lumbago: a part of patient's unknown cause suddenly lumbago occurs, then there is lumbago in another part patient after certain comparatively significantly waist wound.Persistent period short then a couple of days, long then several months, severe patient can for the several years.The scope of flank pain is comparatively extensive, but is mainly manifested in lower waist and waist sacrum buttocks.Lumbago is sometimes comparatively light, sometimes heavier, even severe pain, and waist is inactive, can not stand up, and can not get up, and has a strong impact on life and work.When generally putting down sleeping, pain can alleviate, and after standing and walking, pain increases the weight of.(2) buttocks skelalgia: buttocks skelalgia mostly is and occurs gradually, mainly after buttocks, thigh, outside, little leg outer side are to heel portion or instep radiation for pain, and stand or after walking for a long time, pain increases the weight of, severe patient can not bunk fatigue.In order to ease the pain, the seating posture that patient often takes waist in the wrong, Qu Jing, goes down on one's knees.Leg pain is generally multiple is born in side lower limb, and a few peoples have two leg pain or lower limb alternately pain.Also small number of patients is had to occur lumbago simultaneously with pain on front side of thigh.During intermittent claudication, patient can make lumbago and skelalgia increase the weight of gradually along with travel distance increases.Feel the swollen fiber crops of lower limb acid unbearably, get transference cure after crouching position or seat, muscle strength weakens simultaneously.Prolapse of lumbar intervertebral disc pressuring neural root also causes nerve root injury may occur neural paralysis and Muscle paralysis.
At present, the method for the treatment of prolapse of lumbar intervertebral disc mainly contains the methods such as physical therapy, operative treatment and Drug therapy.Operation method costly, and increases the misery of patient; Although physical therapy method can alleviate the misery of patient, can not effect a radical cure; Western medicine, can relief of symptoms with easing pain and diminishing inflammation, but side effect is larger.Drug treatment reaches therapeutic purposes to restore menstrual flow and invigorate blood circulation.
At present, the patent documentation about treatment osteoarthrosis, intervertebral disc disease also has much.Such as: 1, application number is 201010291248.X, name is called the application for a patent for invention of " a kind of medicine being used for the treatment of prolapse of lumbar intervertebral disc ", and this patent drug is mixed with by Radix Astragali, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Radix Achyranthis Bidentatae, Flos Carthami, teata glycinis, Herba Ephedrae, Herba Asari, Ramulus Cinnamomi, the Radix Paeoniae Alba, Radix Saposhnikoviae, Mel, Rhizoma Zingiberis, the Rhizoma Atractylodis Macrocephalae, Fructus Lycii, Semen Cuscutae, Fructus Psoraleae and Herba Ecliptae to form.2, application number is 201310338590.4, name is called the application for a patent for invention of " a kind of medicine for the treatment of prolapse of lumbar intervertebral disc ", and this patent drug is made up of Radix Achyranthis Bidentatae, Radix Angelicae Sinensis, Radix Angelicae Pubescentis, Herba Taxilli, Fructus Aurantii, Fructus Psoraleae, Radix Saposhnikoviae, Ramulus Cinnamomi, Herba Asari, Rhizoma Chuanxiong, Rhizoma Alismatis, Caulis Spatholobi, Semen Persicae, Flos Carthami and Radix Glycyrrhizae.3, application number is 201210086946.5, name is called the application for a patent for invention of " a kind of medicine for the treatment of prolapse of lumbar intervertebral disc and preparation method thereof ", and this patent drug is mainly prepared from by weight ratio by Radix Aconiti, Radix Aconiti Kusnezoffii, Herba Asari, Cinnabaris, Scorpio, Herba Dendrobii, Realgar, Radix Cyathulae.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of medicine and herbs-partition moxibustion thereof for the treatment of prolapse of lumbar intervertebral disc.Herbs-partition moxibustion of the present invention makes hot moxibustion body with non-burning exothermic mixture, and coordinates the pharmacological action synergism human meridian point of Chinese medicine, and enhanced endogenesis priming effect, strengthens its medical effect, reduces the toxic and side effects risk that medicine is taken in a large number for a long time.In herbs-partition moxibustion of the present invention, moxibustion cream part adopts the present invention to treat lumbar intervertebral disk protrusion pharmaceutical formulation and adjuvant is made.Pharmaceutical formulation of the present invention more lays particular emphasis on and stops the development of bony spur and disappear molten; Adjuvant characteristic more focus on moxibustion cream storage time solid-state stability, and use time biocompatibility and medicament active composition to the osmotic efficiency of human body.Thus the herbs-partition moxibustion of the present invention making it be prepared into strengthens the curative effect to prolapse of lumbar intervertebral disc, the combustion Chinese mugwort herbs-partition moxibustion that the present invention is relatively traditional is safer, reasonable, convenient, effective, is suitable for suitability for industrialized production.
In order to solve the problem, the technical solution used in the present invention is:
The invention provides a kind of medicine for the treatment of prolapse of lumbar intervertebral disc, represent with weight percentage, the medicine of described treatment prolapse of lumbar intervertebral disc is by Radix Aconiti 13 ~ 16%, Radix Aconiti Kusnezoffii 14 ~ 16%, Olibanum 8 ~ 12%, Myrrha 9 ~ 12%, Radix Angelicae Pubescentis 18 ~ 22%, Radix Clematidis 18 ~ 22%, Camphora 3 ~ 6% and Borneolum Syntheticum 4 ~ 6% form.
According to the medicine of above-mentioned treatment prolapse of lumbar intervertebral disc, represent with weight percentage, the medicine of described treatment prolapse of lumbar intervertebral disc is by Radix Aconiti 15%, and Radix Aconiti Kusnezoffii 15%, Olibanum 10%, Myrrha 10%, Radix Angelicae Pubescentis 20%, Radix Clematidis 20%, Camphora 5% and Borneolum Syntheticum 5% form.
A kind of herbs-partition moxibustion for the treatment of prolapse of lumbar intervertebral disc, herbs-partition moxibustion comprises the non-woven fabrics, heater, moxibustion cream and the release paper that scribble pressure sensitive adhesive, ventilative face and the non-woven fabrics laminating scribbling pressure sensitive adhesive of heater, moxibustion patch, in the non-breathable face of heater, moxibustion cream posts release paper; Described moxibustion cream is prepared from by the above-mentioned medicine for the treatment of prolapse of lumbar intervertebral disc of 30 ~ 50wt% and the adjuvant of 50 ~ 70wt%.
According to the herbs-partition moxibustion of above-mentioned treatment prolapse of lumbar intervertebral disc, represent with weight percentage, described adjuvant is by oiliness solvent 40 ~ 50%, transdermal synergist 20 ~ 30%, and fusing point regulator 10 ~ 20% and oil thickeners 10 ~ 20% form;
Described oiliness solvent is any one in sad isopropyl ester, capric acid isopropyl ester, isopropyl myristate, isopropyl palmitate and oleic acid;
Described transdermal synergist is any one in lanoline, lanolin isohexadecyl ether and sorbester p18;
Described fusing point regulator is any one in Cera Flava, glycerol stearate three ester, glyceryl monostearate and paraffin;
Described oil thickeners is the low molecular weight polycaprolactone butylene of the degree of polymerization 1000 ~ 3000.
Treat a preparation method for prolapse of lumbar intervertebral disc herbs-partition moxibustion, described preparation method comprises the following steps:
A, take various raw material according to the ratio of above-mentioned treatment prolapse of lumbar intervertebral disc medicine, except Borneolum Syntheticum, other raw material is ground into respectively 80 ~ 100 object fine powders, and mix homogeneously, obtain mixing fine powders;
B, take various material according to the composition and ratio of above-mentioned adjuvant, various mixing of materials is evenly heated, is heated to 60 ~ 80 DEG C, stop heating when material all melts; Mix homogeneously, is then cooled to 50 ~ 60 DEG C, and according to above-mentioned moxibustion cream ratio, add raw material Borneolum Syntheticum and mixing fine powders that step a takes, mixing and stirring obtains ointment, and ointment is cut after being coated into thin slice, makes moxibustion cream;
C, the moxibustion patch made by step b are in heater non-breathable face, and another ventilative face of heater is affixed on and scribbles on the non-woven fabrics of pressure sensitive adhesive, finally release paper is affixed on above moxibustion cream, makes herbs-partition moxibustion, namely treat the herbs-partition moxibustion of prolapse of lumbar intervertebral disc.
According to the preparation method of above-mentioned treatment prolapse of lumbar intervertebral disc herbs-partition moxibustion, ointment described in step b is coated with, and its coating weight is every 100cm
2on carrier material, the amount of unction is 3.5 ~ 4.5g.
According to the preparation method of above-mentioned treatment prolapse of lumbar intervertebral disc herbs-partition moxibustion, described carrier material is non-woven fabrics, paper, foam or hot blast compound nonwoven cloth.
Namely the product be prepared into is treated prolapse of lumbar intervertebral disc herbs-partition moxibustion and is packaged in low ventilating plastic bag or clad aluminum foil bag by the present invention.
the performance of the various crude drug of the present invention:
Radix Aconiti: this product acrid in the mouth, hardship, hot in nature; Very toxic.Enter the heart, liver,kidney,spleen warp.Effect: the effects such as this product has expelling wind and removing dampness, antalgic; Be mainly used in anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type have a pain.Radix Aconiti tincture external energy chafe, produces feeling of numbness then, therefore the outer analgesics being used as some neuralgia and rheumatism.
Radix Aconiti Kusnezoffii: this product acrid in the mouth, hardship, hot in nature; GUIXIN, liver,kidney,spleen warp.Effect: this product has expelling wind and removing dampness, dispelling cold by warming the meridian, the effects such as reducing swelling and alleviating pain; The diseases such as be mainly used in anemofrigid-damp arthralgia, arthralgia, colic of cold type is had a pain, traumatic injury pain, trusted subordinate's cold type of pain.
Olibanum: this product acrid in the mouth, hardship, warm in nature; Enter the heart, liver, spleen channel.Effect: this product has regulating qi and activating blood, circulation of qi promoting relieves the pain, detumescence and promoting granulation, analgesic therapy, chases after the effects such as poison; Be mainly used in congestion and block all pains card, as rheumatic arthralgia, WEIJIA gather, the disease such as traumatic injury.
Myrrha: this product acrid in the mouth, hardship, property is put down; Enter liver, spleen, the heart, kidney channel.Effect: the effects such as this product has promoting blood circulation and stopping pain, detumescence and promoting granulation; Be mainly used in the traumatic injury caused by congestion retardance, the stasis of blood is stagnant to swell and ache, ulcer sore pain, raw property arthralgia, sciatica, oral cavity pain, has sore throat, cold cough, the diseases such as eczema abscess.
Radix Angelicae Pubescentis: this product acrid in the mouth, hardship, slightly warm in nature; Return liver, kidney, urinary bladder channel.Effect: this product has the effect such as expelling wind and dampness, dispersing cold for relieving pain; Be usually used in anemofrigid-damp arthralgia, lumbocrural pain, few cloudy volt wind headache, the diseases such as headache toothache.
Radix Clematidis: this product acrid in the mouth, salty, warm in nature; Return urinary bladder channel.Effect: this product has expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the effects such as the loose hypochondriac lump; Be mainly used in gout insensitive impediment, rheumatic arthralgia, numb limbs and tense tendons, knee joint cold type of pain, the contracture of muscle arteries and veins, joint stuffiness, beriberi, malaria, lump in the abdomen, tetanus, the diseases such as tonsillitis.
Camphora: this product acrid in the mouth, hot in nature.Effect: this product has orifice opening, qi stagnation removing, wards off the effects such as foul, killing parasites for relieving itching, reducing swelling and alleviating pain; Cure mainly the diseases such as scabies pruritus, traumatic pain, toothache.
Borneolum Syntheticum: have another name called sheet brain, Fructus Citri tangerinae sheet, Borneolum Syntheticum, MEIHUA BINGPIAN, Dipterocarpus pilosus, Flos Mume brain, Borneolum Syntheticum brain, Mei Bing etc., being that resin and the volatile oil processed goods of Spore density Borneolum Syntheticum extracts the crystallization obtained, is near pure dextro Borneolum Syntheticum.Also have and chemically synthesize.It can be used for for excess syndrome of stroke coma, for conjunctival congestion and swelling pain, sore throat aphtha, swells and ache for skin infection, does not hold back after bursting.
The compatibility mechanism of prescription of the present invention: prescription compatibility of the present invention is rigorous, through sick place.Radix Aconiti, Radix Aconiti Kusnezoffii all have dispelling cold by warming the meridian, effect of promoting blood circulation and stopping pain, and both share pharmacologically cumulative effect.Olibanum, Myrrha have the effect of promoting the circulation of QI to relieve pain, detumescence and promoting granulation, and both share pharmacologically cumulative effect.Radix Angelicae Pubescentis, Radix Clematidis have removing obstruction in the collateral to relieve pain, expelling wind and dampness, and both couplings can increase immunity of organisms, pharmacologically have accumulative action.Camphora, Borneolum Syntheticum have the pharmacological action of reducing swelling and alleviating pain, and both share and the permeability of skin can be made to strengthen, and are beneficial to the absorption of medicine, and two medicines and Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Angelicae Pubescentis, Radix Clematidis, Olibanum, Myrrha are pharmacologically having synergism.
Full side has in a word: strengthening the tendons and bones, antalgic, blood circulation promoting and blood stasis dispelling, transdermal characteristic are strong, the function of raising curative effect.
positive beneficial effect of the present invention:
1, the present invention treats prolapse of lumbar intervertebral disc herbs-partition moxibustion by moxibustion and medication organic assembling one, heat, medicine-physics and biochemical factors cooperatively interact synergism human meridian point, enhanced endogenesis priming effect, strengthens its medical effect, reduces the toxic and side effects risk that medicine is taken in a large number for a long time.Thus the curative effect strengthened prolapse of lumbar intervertebral disc, the combustion Chinese mugwort herbs-partition moxibustion that the present invention is relatively traditional is more reasonable, convenient, effective, is suitable for suitability for industrialized production.
2, the moxibustion cream of herbs-partition moxibustion of the present invention adopts the composite of hot-wind nonwoven cloth and plastic foil and hot blast compound nonwoven cloth to be carrier, can be adhered on it by ointment preferably and be beneficial to shaping, melts and not easily overflow during use.In addition, the adjuvant that the present invention adopts is non-stimulated to skin to skin good biocompatibility, and Drug Percutaneous Absorption efficiency is high.
3, the traditional Chinese medical science is thought, prolapse of lumbar intervertebral disc Chang Yin by force unbalance or bad life habits and Liver and kidney insufficiency of vital energy and blood, caused by energy stagnation and blood stasis.Moxibustion spread manuer in holes as prolapse of lumbar intervertebral disc at yao yang kuan cave and Shenshu etc. on the one hand can invigorating kidney qi; The present invention adopts Radix Aconiti, Radix Aconiti Kusnezoffii, Olibanum, Myrrha, Radix Angelicae Pubescentis, Radix Clematidis, Camphora and Borneolum Syntheticum eight kinds of medicine reasonable compatibilities, thus makes its medicine have the merit of expelling wind and dampness for relieving pain, can remove rheumatism, vessel conditioning, bone and muscle strengthening, the profit that nourishes blood muscle, reaches the eliminating evil treatment of softening the hard mass originally.
4, application herbs-partition moxibustion treatment of the present invention prolapse of lumbar intervertebral disc, evident in efficacy, and be free from side effects.Herbs-partition moxibustion that prolapse of lumbar intervertebral disc medicine makes carries out treatment prolapse of lumbar intervertebral disc to utilize the present invention to treat, and its clinical observation result of the test is as follows:
Observe case: 54 examples, male 27 example, women 27 example, minimum 39 years old maximum 72 years old, 57.4 years old mean age.
Matched group: 54 examples.
Therapeutic Method: treatment group the present invention treats the herbs-partition moxibustion external application of prolapse of lumbar intervertebral disc, is affixed on yao yang kuan or Shenshu or pressure pain point; Paste every day one and use 5 days continuously.Matched group oral ibuprofen every day twice, each 400mg, take 5 days continuously.
Therapeutic outcome: effective 35 examples for the treatment of group, effective 15 examples, invalid 4 examples; Effective 22 examples of matched group, effective 27 examples, invalid 8 examples (RIDIT analyzes P>0.05, treatment group and matched group there was no significant difference).
model case:
1, Wang, man, 50 years old, Suixian County, Henan Province peasant, suffered from intervertebral disk hernia 5 years, failed to cure through multi-treatment.Upon somebody's introduction, adopt the present invention to treat the herbs-partition moxibustion of prolapse of lumbar intervertebral disc once-a-day (product of this herbs-partition moxibustion prepared by embodiment 5 and the present invention treat prolapse of lumbar intervertebral disc herbs-partition moxibustion), one time one subsides, subsides Shenshu cave sticks 5 weeks, basic healing, follows up a case by regular visits to and does not send out so far.
2, Zhang, man, 40 years old, Miyang County, Henan Province peasant, suffered from intervertebral disk hernia 3 years, and Post operation fails to cure.Upon somebody's introduction, the present invention is adopted to treat the herbs-partition moxibustion of prolapse of lumbar intervertebral disc once-a-day (product of this herbs-partition moxibustion prepared by embodiment 5 and the present invention treat prolapse of lumbar intervertebral disc herbs-partition moxibustion), one time one subsides, are affixed on finger pressure pain spot and yao yang kuan sticks 6 weeks, and recovery from illness is not sent out so far.
3, Lee, female, 38 years old, Fugou County, Henan Province peasant, suffered from intervertebral disk hernia 4 years, failed to cure through multi-treatment.Upon somebody's introduction, the present invention is adopted to treat the herbs-partition moxibustion of prolapse of lumbar intervertebral disc once-a-day (product of this herbs-partition moxibustion prepared by embodiment 5 and the present invention treat prolapse of lumbar intervertebral disc herbs-partition moxibustion), one time one subsides, Shenshu and yao yang kuan alternately stick 5 weeks, are almost recovered.
4, Liu, female, 36 years old, Henan Province city of Zhongmou County peasant, suffered from intervertebral disk hernia 3 years, failed to cure through multi-treatment.Upon somebody's introduction, the present invention is adopted to treat the herbs-partition moxibustion of prolapse of lumbar intervertebral disc once-a-day (product of this herbs-partition moxibustion prepared by embodiment 6 and the present invention treat prolapse of lumbar intervertebral disc herbs-partition moxibustion), one time one subsides, are affixed on finger pressure pain spot and yao yang kuan sticks 5 weeks, and recovery from illness is not sent out so far.
5, Korea Spro, man, 46 years old, Zhengzhou City Henan Province workers in enterprise, suffered from intervertebral disk hernia 2 years, failed to cure through multi-treatment.Upon somebody's introduction, the present invention is adopted to treat the herbs-partition moxibustion of prolapse of lumbar intervertebral disc once-a-day (product of this herbs-partition moxibustion prepared by embodiment 8 and the present invention treat prolapse of lumbar intervertebral disc herbs-partition moxibustion), one time one subsides, are affixed on finger pressure pain spot and yao yang kuan sticks 5 weeks, and recovery from illness is not sent out so far.
detailed description of the invention:
Set forth the present invention further below in conjunction with embodiment, but do not limit content of the present invention.
Embodiment 1:
The present invention treats the medicine of prolapse of lumbar intervertebral disc, represents with weight percentage, and the medicine of described treatment prolapse of lumbar intervertebral disc is by Radix Aconiti 15%, and Radix Aconiti Kusnezoffii 15%, Olibanum 10%, Myrrha 10%, Radix Angelicae Pubescentis 20%, Radix Clematidis 20%, Camphora 5% and Borneolum Syntheticum 5% form.
Embodiment 2:
The present invention treats the medicine of prolapse of lumbar intervertebral disc, represents with weight percentage, and the medicine of described treatment prolapse of lumbar intervertebral disc is by Radix Aconiti 13%, and Radix Aconiti Kusnezoffii 16%, Olibanum 12%, Myrrha 9%, Radix Angelicae Pubescentis 18%, Radix Clematidis 22%, Camphora 6% and Borneolum Syntheticum 4% form.
Embodiment 3:
The present invention treats the medicine of prolapse of lumbar intervertebral disc, represents with weight percentage, and the medicine of described treatment prolapse of lumbar intervertebral disc is by Radix Aconiti 16%, and Radix Aconiti Kusnezoffii 14%, Olibanum 8%, Myrrha 12%, Radix Angelicae Pubescentis 22%, Radix Clematidis 18%, Camphora 4% and Borneolum Syntheticum 6% form.
Embodiment 4:
The present invention treats the medicine of prolapse of lumbar intervertebral disc, represents with weight percentage, and the medicine of described treatment prolapse of lumbar intervertebral disc is by Radix Aconiti 14%, and Radix Aconiti Kusnezoffii 15%, Olibanum 11%, Myrrha 11%, Radix Angelicae Pubescentis 21%, Radix Clematidis 19%, Camphora 5% and Borneolum Syntheticum 4% form.
Embodiment 5:
The present invention treats the herbs-partition moxibustion of prolapse of lumbar intervertebral disc, herbs-partition moxibustion comprises the non-woven fabrics, heater, moxibustion cream and the release paper that scribble pressure sensitive adhesive, ventilative face and the non-woven fabrics laminating scribbling pressure sensitive adhesive of heater, moxibustion patch, in the non-breathable face of heater, moxibustion cream posts release paper; Described moxibustion cream is prepared from by the adjuvant of the medicine and 60wt% for the treatment of prolapse of lumbar intervertebral disc described in 40wt% embodiment 1; Described adjuvant is by isopropyl palmitate 40%, lanoline 20%, and the polybutene 20% of Cera Flava 20% and the degree of polymerization 2000 forms.
The preparation method for the treatment of prolapse of lumbar intervertebral disc herbs-partition moxibustion, the detailed step of this preparation method is as follows:
A, take various raw material according to the ratio for the treatment of prolapse of lumbar intervertebral disc medicine described in embodiment 1, except Borneolum Syntheticum, other raw material is ground into respectively 80 ~ 100 object fine powders, and mix homogeneously, obtain mixing fine powders;
B, take various material according to the composition and ratio of adjuvant described in embodiment 5, various mixing of materials is evenly heated, is heated to 70 DEG C, stop heating when material all melts; Mix homogeneously, is then cooled to less than 50 DEG C, and according to moxibustion cream ratio described in embodiment 5, add raw material Borneolum Syntheticum and mixing fine powders that step a takes, mixing and stirring obtains ointment, and ointment is coated into thin slice, and (coating weight is every 100cm
2on hot blast compound nonwoven cloth, the amount of unction is 4.0g), cut after coating, make moxibustion cream;
C, the moxibustion patch made by step b are in heater non-breathable face, and another ventilative face of heater is affixed on and scribbles on the non-woven fabrics of pressure sensitive adhesive, finally release paper is affixed on above moxibustion cream, makes herbs-partition moxibustion, namely treat the herbs-partition moxibustion of prolapse of lumbar intervertebral disc.
Embodiment 6: substantially the same manner as Example 5, difference is:
Described moxibustion cream is prepared from by the adjuvant of the medicine and 50wt% for the treatment of prolapse of lumbar intervertebral disc described in 50wt% embodiment 2; Described adjuvant is by sad isopropyl ester 45%, lanolin isohexadecyl ether 25%, and the polybutene 15% of glycerol stearate three ester 15% and the degree of polymerization 3000 forms.
The preparation method difference from Example 5 for the treatment of prolapse of lumbar intervertebral disc herbs-partition moxibustion is:
In step a: take various raw material according to the ratio for the treatment of prolapse of lumbar intervertebral disc medicine described in embodiment 2;
In step b: take various material according to the composition and ratio of adjuvant described in embodiment 6; According to moxibustion cream ratio described in embodiment 6.
Embodiment 7: substantially the same manner as Example 5, difference is:
Described moxibustion cream is prepared from by the adjuvant of the medicine and 55wt% for the treatment of prolapse of lumbar intervertebral disc described in 45wt% embodiment 3; Described adjuvant is by oleic acid 50%, sorbester p18 30%, and the polybutene 10% of paraffin 10% and the degree of polymerization 3000 forms.
The preparation method difference from Example 5 for the treatment of prolapse of lumbar intervertebral disc herbs-partition moxibustion is:
In step a: take various raw material according to the ratio for the treatment of prolapse of lumbar intervertebral disc medicine described in embodiment 3;
In step b: take various material according to the composition and ratio of adjuvant described in embodiment 7; According to moxibustion cream ratio described in embodiment 7.
Embodiment 8: substantially the same manner as Example 5, difference is:
Described moxibustion cream is prepared from by the adjuvant of the medicine and 70wt% for the treatment of prolapse of lumbar intervertebral disc described in 30wt% embodiment 4; Described adjuvant is by isopropyl myristate 42%, lanoline 28%, and the polybutene 12% of Cera Flava 18% and the degree of polymerization 2000 forms.
The preparation method difference from Example 5 for the treatment of prolapse of lumbar intervertebral disc herbs-partition moxibustion is:
In step a: take various raw material according to the ratio for the treatment of prolapse of lumbar intervertebral disc medicine described in embodiment 4;
In step b: take various material according to the composition and ratio of adjuvant described in embodiment 8; According to moxibustion cream ratio described in embodiment 8.
Claims (6)
1. treat the herbs-partition moxibustion of prolapse of lumbar intervertebral disc for one kind, it is characterized in that, herbs-partition moxibustion comprises the non-woven fabrics, heater, moxibustion cream and the release paper that scribble pressure sensitive adhesive, ventilative face and the non-woven fabrics laminating scribbling pressure sensitive adhesive of heater, moxibustion patch, in the non-breathable face of heater, moxibustion cream posts release paper; Described moxibustion cream treats the medicine of prolapse of lumbar intervertebral disc by 30 ~ 50wt% and the adjuvant of 50 ~ 70wt% is prepared from;
Represent with weight percentage, the medicine of described treatment prolapse of lumbar intervertebral disc is by Radix Aconiti 13 ~ 16%, and Radix Aconiti Kusnezoffii 14 ~ 16%, Olibanum 8 ~ 12%, Myrrha 9 ~ 12%, Radix Angelicae Pubescentis 18 ~ 22%, Radix Clematidis 18 ~ 22%, Camphora 3 ~ 6% and Borneolum Syntheticum 4 ~ 6% form.
2. the herbs-partition moxibustion for the treatment of prolapse of lumbar intervertebral disc according to claim 1, it is characterized in that: represent with weight percentage, the medicine of described treatment prolapse of lumbar intervertebral disc is by Radix Aconiti 15%, Radix Aconiti Kusnezoffii 15%, Olibanum 10%, Myrrha 10%, Radix Angelicae Pubescentis 20%, Radix Clematidis 20%, Camphora 5% and Borneolum Syntheticum 5% form.
3. the herbs-partition moxibustion for the treatment of prolapse of lumbar intervertebral disc according to claim 1, it is characterized in that: represent with weight percentage, described adjuvant is by oiliness solvent 40 ~ 50%, transdermal synergist 20 ~ 30%, and fusing point regulator 10 ~ 20% and oil thickeners 10 ~ 20% form;
Described oiliness solvent is any one in sad isopropyl ester, capric acid isopropyl ester, isopropyl myristate, isopropyl palmitate and oleic acid;
Described transdermal synergist is any one in lanoline, lanolin isohexadecyl ether and sorbester p18;
Described fusing point regulator is any one in Cera Flava, glycerol stearate three ester, glyceryl monostearate and paraffin;
Described oil thickeners is the low molecular weight polycaprolactone butylene of the degree of polymerization 1000 ~ 3000.
4. treat a preparation method for prolapse of lumbar intervertebral disc herbs-partition moxibustion, it is characterized in that, described preparation method comprises the following steps:
A, take various raw material according to the ratio for the treatment of prolapse of lumbar intervertebral disc medicine described in claim 1, except Borneolum Syntheticum, other raw material is ground into respectively 80 ~ 100 object fine powders, and mix homogeneously, obtain mixing fine powders;
B, take various material according to the composition and ratio of adjuvant described in claim 3, various mixing of materials is evenly heated, is heated to 60 ~ 80 DEG C, stop heating when material all melts; Mix homogeneously, is then cooled to 50 ~ 60 DEG C, and according to moxibustion cream ratio described in claim 1, add raw material Borneolum Syntheticum and mixing fine powders that step a takes, mixing and stirring obtains ointment, and ointment is cut after being coated into thin slice, makes moxibustion cream;
C, the moxibustion patch made by step b are in heater non-breathable face, and another ventilative face of heater is affixed on and scribbles on the non-woven fabrics of pressure sensitive adhesive, finally release paper is affixed on above moxibustion cream, makes herbs-partition moxibustion, namely treat the herbs-partition moxibustion of prolapse of lumbar intervertebral disc.
5. the preparation method for the treatment of prolapse of lumbar intervertebral disc herbs-partition moxibustion according to claim 4, is characterized in that, ointment described in step b is coated with, and its coating weight is every 100cm
2on carrier material, the amount of unction is 3.5 ~ 4.5g.
6. the preparation method for the treatment of prolapse of lumbar intervertebral disc herbs-partition moxibustion according to claim 5, is characterized in that: described carrier material is paper, foam or hot blast compound nonwoven cloth.
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| CN104189124A (en) * | 2014-09-11 | 2014-12-10 | 洛阳民华生物科技有限公司 | Traditional Chinese medicine oil used for reducing pains of necks, shoulders, waists and legs and preparation method thereof |
| CN104173487B (en) * | 2014-09-12 | 2016-08-17 | 洛阳民华生物科技有限公司 | The warm patch of a kind of Chinese medicine for improving neck, shoulder, waist and leg pain and preparation technology thereof |
| CN105411838B (en) * | 2014-09-15 | 2018-09-07 | 李建书 | Environmental protection and energy saving moxibustion temperature control leads medicine synergistic film |
| CN105125674A (en) * | 2015-09-15 | 2015-12-09 | 河南省超亚医药器械有限公司 | Medicament for treating hyperostosis and medicament-separated moxibustion of medicament |
| CN107596214A (en) * | 2017-09-11 | 2018-01-19 | 刘代炳 | A kind of tcm product for moxa-moxibustion is set with |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101002867A (en) * | 2006-12-30 | 2007-07-25 | 于世礼 | External application medicine for treating vertebrae lumbales hyperosteogeny |
| CN101020019A (en) * | 2007-03-06 | 2007-08-22 | 林冶 | Dogskin plaster and its prepn process |
| CN101890150A (en) * | 2010-03-20 | 2010-11-24 | 李志刚 | Novel and special Likexiao |
| CN101897838A (en) * | 2009-05-26 | 2010-12-01 | 邱天道 | External hot applied mud moxibustion for human body and application method thereof |
| CN102274475A (en) * | 2011-07-15 | 2011-12-14 | 莫桂森 | Ostalgia moxibustion |
-
2014
- 2014-01-16 CN CN201410019504.8A patent/CN103768175B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101002867A (en) * | 2006-12-30 | 2007-07-25 | 于世礼 | External application medicine for treating vertebrae lumbales hyperosteogeny |
| CN101020019A (en) * | 2007-03-06 | 2007-08-22 | 林冶 | Dogskin plaster and its prepn process |
| CN101897838A (en) * | 2009-05-26 | 2010-12-01 | 邱天道 | External hot applied mud moxibustion for human body and application method thereof |
| CN101890150A (en) * | 2010-03-20 | 2010-11-24 | 李志刚 | Novel and special Likexiao |
| CN102274475A (en) * | 2011-07-15 | 2011-12-14 | 莫桂森 | Ostalgia moxibustion |
Non-Patent Citations (1)
| Title |
|---|
| 骨质增生的中医药治疗现状;毛照海;《甘肃中医》;19921231;第45-48页 * |
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Denomination of invention: Drugs and medicine separated moxibustion for the treatment of lumbar disc herniation Effective date of registration: 20210209 Granted publication date: 20150610 Pledgee: Ping An Bank Ltd. Beijing branch Pledgor: HENAN SUPER ASIA MEDICAL EQUIPMENT Co.,Ltd. Registration number: Y2021980001155 |
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Date of cancellation: 20220722 Granted publication date: 20150610 Pledgee: Ping An Bank Ltd. Beijing branch Pledgor: HENAN SUPER ASIA MEDICAL EQUIPMENT Co.,Ltd. Registration number: Y2021980001155 |