CN102988760B - Traditional Chinese medicine composition for treating chlamydia psittaci disease - Google Patents
Traditional Chinese medicine composition for treating chlamydia psittaci disease Download PDFInfo
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- CN102988760B CN102988760B CN201210246165.8A CN201210246165A CN102988760B CN 102988760 B CN102988760 B CN 102988760B CN 201210246165 A CN201210246165 A CN 201210246165A CN 102988760 B CN102988760 B CN 102988760B
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Abstract
The invention provides a traditional Chinese medicine composition for treating chlamydia psittaci disease, which comprises radix scutellariae, rhizoma blechni, fructus mume, fructus forsythiae, rhizoma polygoni cuspidati, rhizoma bletillae, ginseng, rhizoma atractylodis macrocephalae, radix sophorae flavescentis, radix pulsatillae, caulis spatholobi and radix puerariae. The traditional Chinese medicine composition provided by the invention has the advantages of obvious curative effect, high cure rate, rare recurrence and the like in treating the chicken suffering chlamydia psittaci disease.
Description
Technical field
The present invention relates to herbal medicine technical field, relate in particular to a kind of Chinese medicine composition that is used for the treatment of chlamydia psittaci disease.
Background technology
Chlamydia is the pathogenic microorganism between rickettsia and virus, is the microorganism of special sexual cell endoparasitism, has complete cell wall, without 3-O-.alpha.-carboxyethyl-D-glucosamine..Avian chlamydiosis has another name called ornithosis, psittacosis, has trachoma, pneumonia and 3 kinds of chlamydia of psittacosis.The chlamydia psittaci disease pathogen of fowl has all formed potential threat to the birdss such as broiler and the mankind at present, and therefore, in the poultry cultivation processes such as broiler, its popular generation can cause the morbidity of the mankind and birds.Easily there is actute infection in broiler, cold season, 23 ages in days, the easy intermittence of 33 age in days, be asthmoid respiration, breathes out, and necking down is air-breathing, and hot season, death pipes.Sick chicken is discharged yellow green glue peptone shape feces.The broiler symptom of most of natural infections is not obvious, and is a property crossed.Cuing open the visible pathological changes of inspection is heart enlargement, and visceral pericardium thickens, hyperemia, and surface has fibrinous exudate to cover, and balloon membranes thickens, abdominal cavity serous coat and mesenteric vein hyperemia, surface coverage cystose white fiber disposition exudate.
Chinese herbal medicine is China's traditional medicine, for chemical synthetic drug, Chinese herbal medicine has plurality of active ingredients, not only have advantages of that toxicity is low, be difficult for having side effects, pathogenic microorganism is difficult for producing drug resistance to it, and in anti-bacteria and anti-virus, can also promote growth of animal, strengthen the immune function of animal, improve body disease-resistant power.But, at present, being used for the treatment of the Chinese herbal medicine of chlamydia psittaci disease and important compound preparation and having that formula is not smart, kind is single, therapeutic effect is also not satisfactory.
Summary of the invention
Technical problem to be solved by this invention is to be to provide a kind of novel Chinese medicine composition that is used for the treatment of chlamydia psittaci disease and preparation method thereof, sick treatment has evident in efficacy to chlamydia psittaci to adopt this Chinese medicine composition, cure rate is high, is difficult for the advantages such as recurrence.
In order to solve the problems of the technologies described above, the invention provides a kind of Chinese medicine composition that is used for the treatment of chlamydia psittaci disease, it comprises: Radix Scutellariae, Rhizoma Osmundae, Fructus Mume, Fructus Forsythiae, Rhizoma Polygoni Cuspidati, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, Radix Sophorae Flavescentis, the Radix Pulsatillae, Caulis Spatholobi, Radix Puerariae.
Wherein, the ratio of weight and number of the each component in described Chinese medicine composition is, Radix Scutellariae 65～75 weight portions, Rhizoma Osmundae 11～13 weight portions, Fructus Mume 30～35 weight portions, Fructus Forsythiae 25～30 weight portions, Rhizoma Polygoni Cuspidati 20～25 weight portions, Pseudobulbus Bletillae (Rhizoma Bletillae) 9～12 weight portions, Radix Ginseng 14～18 weight portions, the Rhizoma Atractylodis Macrocephalae 17～20 weight portions, Radix Sophorae Flavescentis 12～15 weight portions, the Radix Pulsatillae 16～20 weight portions, Caulis Spatholobi 12～16 weight portions, Radix Puerariae 7～10 weight portions.
Wherein, described Chinese medicine composition dosage form can be decoction, powder, honey refining pill, hydration pill, tablet, capsule, oral liquid, granule, colloid or syrup.
Beneficial effect of the present invention:
With respect to the medicine that is used for the treatment of chlamydia psittaci disease of the prior art, sick treatment has the advantages such as evident in efficacy, high, the difficult recurrence of cure rate to chlamydia psittaci to adopt this Chinese medicine composition.
The specific embodiment
The invention provides a kind of like this Chinese medicine composition that is used for the treatment of chlamydia psittaci disease, it comprises: Radix Scutellariae, Rhizoma Osmundae, Fructus Mume, Fructus Forsythiae, Rhizoma Polygoni Cuspidati, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, Radix Sophorae Flavescentis, the Radix Pulsatillae, Caulis Spatholobi, Radix Puerariae.
Radix Scutellariae: bitter in the mouth, cold in nature, enter the heart, lung, stomach, gallbladder, large intestine channel, there is heat clearing and damp drying, eliminating fire and detoxication, antiabortive, the effect of hemostasis, is mainly used in diarrhoea, dysentery, jaundice, pyretic stranguria due to damp and hot; Cough due to lung-heat, thirsty pharyngalgia, also can be used for excessive fetal movement due to heat in pregnancy, and pyretic toxicity pathogenic fire is invaded the swollen card of carbuncle sore poison of excessive skin.That Radix Scutellariae has is antipyretic, calm, blood pressure lowering, diuresis, reduction capillary permeability, suppress the effects such as intestinal tube wriggling, staphylococcus, blood dissolubility streptococcus, Diplococcus pneumoniae, Bacillus typhi, dysentery coccus, newcastle, bacillus pyocyaneus are had to certain inhibitory action, upper respiratory tract infection, chronic bronchitis, bacillary dysentery etc. are had to good curative effect.
Fructus Mume: sour in the mouth, puckery, flat, enter liver, spleen, lung, large intestine channel, to astringe the lung, astringing intestine to stop diarrhea, promotes the production of body fluid, and the effect of relieving colic caused by ascaris, is mainly used in chronic cough of deficiency lung; Deficiency-heat excessive thirst; Chronic malaria; Chronic diarrhea; Dysentery; Have blood in stool; Hematuria; Metrorrhagia; Ascariasis of biliary tract stomachache; Vomiting; The cards such as ancylostomiasis
Rhizoma Osmundae: acrid in the mouth, hardship, cold.Return lung meridian.Tool heat-clearing and toxic substances removing, cooling blood for hemostasis, the function of parasite killing.Cure mainly seasonal pathogen sense, partial heat person, heating is heavy, aversion to cold is light, it is red to have a headache, swallow, pharyngeal swelling, xerostomia and thirsty, red tongue, white and thin fur, floating pulse.
Fructus Forsythiae: bitter in the mouth, be slightly cold, enter the heart, lung, small intestine meridian, there is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, the effect of dispelling wind and heat pathogens.Be mainly used in warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction, the diseases such as clearing away heart-fire.
Rhizoma Polygoni Cuspidati: mildly bitter flavor, cold nature, return liver, gallbladder, lung meridian, there is the effect of expelling wind and removing dampness, dissipating blood stasis analgesic therapy, preventing phlegm from forming and stopping coughing, for arthralgia, jaundice due to damp-heat, amenorrhea ， WEIJIA, cough with copious phlegm, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus.Rhizoma Polygoni Cuspidati has and suppresses and killing action staphylococcus aureus, Staphylococcus albus, Hemolytic streptococcus, micrococcus catarrhalis, newcastle, Bacillus proteus, bacillus pyocyaneus etc.
Pseudobulbus Bletillae (Rhizoma Bletillae): property hardship, sweet, puckery, cold nature, enters lung, stomach, Liver Channel, has the effect of astringing to arrest bleeding, detumescence life, is mainly used in the hemoptysis of the deficiency of the lung, pulmonary tuberculosis, yin asthenia generating intrinsic heat, the haematemesis of thermal burn stomach network; The cards such as traumatic hemorrhage, Pseudobulbus Bletillae (Rhizoma Bletillae) has erythrocyte aggregation and local hemostatic the renting of promotion, has an anastalsis to gastric duodenal ulcer is hemorrhage.
Radix Ginseng: property is flat, sweet in the mouth, micro-hardship, tepor, enter spleen, lung meridian, heart channel, have strongly invigorating primordial QI, multiple arteries and veins is admittedly de-, invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, the calm the nerves effect of Fructus Alpiniae Oxyphyllae, be mainly used in that impairment caused by overstrain is deficient, lack of appetite, asthenia, regurgitation are told food, stool lingering diarrhea, empty cough with asthma are short, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, frequent micturition, quench one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion and prolonged deficiency multiple, the disease of all qi-blood-body fluid deficiencies.
Radix Sophorae Flavescentis: bitter in the mouth; Cold in nature, enter liver, kidney, large intestine, small intestinal, bladder, heart channel, there is heat clearing and damp drying; The effect of wind dispelling insecticide, is mainly used in damp-heat dysentery; Discharging fresh blood stool; Jaundice; Dysuria; Edema; Leukorrhagia; Pudendal pruritus; Scabies; Leprosy; Skin pruritus; Noxious dampness skin infection.
Pseudobulbus Bletillae (Rhizoma Bletillae) hemostasis, male earner convergence, and be especially apt to tonifying the lung hemostasis, have the merit of detumescence and promoting granulation concurrently.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth, sweet, temperature, returns spleen, stomach warp, has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect, is mainly used in that insufficiency of the spleen lack of appetite, abdominal distention are had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
The Radix Pulsatillae: bitter in the mouth, cold in nature, return stomach, large intestine channel, there is heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, effect of removing dampness and killing parasites, is mainly used in pyretic toxicity dysentery, epistaxis, internal hemorrhoid with bleeding, leukorrhagia, pudendal pruritus, carbuncle skin ulcer, scrofula.
Caulis Spatholobi: bitter in the mouth, sweet, temperature, returns liver, kidney channel, enriches blood, and invigorates blood circulation, and the effect of dredging collateral, is mainly used in for menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.
Radix Puerariae: sweet in the mouth, pungent, cool in nature, enter spleen, stomach warp, there is inspiration gastric qi, clearing away heat and promoting production of body fluid, expelling pathogenic factors from muscles is delivered, raw positive, oozes the effect of rash, is mainly used in fever caused by exogenous pathogens, headache, stiff nape and back, calentura is thirsty, quenches one's thirst; Diarrhea due to hypofunction of the spleen, the cards such as clear YANG failing to ascend, intrinsic heat during the light clear expelling heat from the exterior of Radix Puerariae is wet.
Further preferably, the Chinese medicine composition that is used for the treatment of chlamydia psittaci disease described in is only made up of said components.
In the described Chinese medicine composition that is used for the treatment of chlamydia psittaci disease, the ratio of weight and number of various components can be preferably: Radix Scutellariae 55～75 weight portions, Rhizoma Osmundae 9～13 weight portions, Fructus Mume 25～35 weight portions, Fructus Forsythiae 20～30 weight portions, Rhizoma Polygoni Cuspidati 15～25 weight portions, Pseudobulbus Bletillae (Rhizoma Bletillae) 7～12 weight portions, Radix Ginseng 10～18 weight portions, the Rhizoma Atractylodis Macrocephalae 15～20 weight portions, Radix Sophorae Flavescentis 9～15 weight portions, the Radix Pulsatillae 12～20 weight portions, Caulis Spatholobi 8～16 weight portions, Radix Puerariae 5～10 weight portions.
In the described Chinese medicine composition that is used for the treatment of animal chlamydia psittaci disease, the ratio of weight and number of various components also can be more preferably: Radix Scutellariae 65～75 weight portions, Rhizoma Osmundae 11～13 weight portions, Fructus Mume 30～35 weight portions, Fructus Forsythiae 25～30 weight portions, Rhizoma Polygoni Cuspidati 20～25 weight portions, Pseudobulbus Bletillae (Rhizoma Bletillae) 9～12 weight portions, Radix Ginseng 14～18 weight portions, the Rhizoma Atractylodis Macrocephalae 17～20 weight portions, Radix Sophorae Flavescentis 12～15 weight portions, the Radix Pulsatillae 16～20 weight portions, Caulis Spatholobi 12～16 weight portions, Radix Puerariae 7～10 weight portions.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure of reaching technique effect can fully understand and implement according to this.
The preparation of embodiment 1 Chinese medicine composition 1
65g Radix Scutellariae, 11g Rhizoma Osmundae, 30g Fructus Mume, 25g Fructus Forsythiae, 20g Rhizoma Polygoni Cuspidati, 9g Pseudobulbus Bletillae (Rhizoma Bletillae), 14g Radix Ginseng, the 17g Rhizoma Atractylodis Macrocephalae, 12g Radix Sophorae Flavescentis, the 16g Radix Pulsatillae, 12g Caulis Spatholobi, 7g Radix Puerariae are mixed and pulverized; Mixture after pulverizing is added and in 850g distilled water, soaks and decoct 3 times, decoct 1 hour at every turn, merging decoction liquor is also concentrated into thick shape; Adding subsequently concentration is 95% ethanol, fully stirring and evenly mixing, and being adjusted to alcohol content is 65%, precipitate 36 hours, filters acquisition the first alcoholic solution; It is 95% the abundant stirring and evenly mixing of ethanol that the first alcoholic solution is added to concentration again, and being adjusted to alcohol content is 75%, precipitates 36 hours, filters, and obtains the second alcoholic solution; The second alcoholic solution obtaining is concentrated into without alcohol taste, add 600g distilled water cold preservation precipitation 24 hours, filter, filtrate is concentrated, dry, pulverize, obtain 100 object graininess Chinese medicine composition 1 of the present invention, described Chinese medicine composition 1 is put into water and dissolve, stir acquisition oral liquid, crude drug amount 1g/ml.
The preparation of embodiment 2 Chinese medicine compositions 2
75g Radix Scutellariae, 13g Rhizoma Osmundae, 40g Fructus Mume, 30g Fructus Forsythiae, 25g Rhizoma Polygoni Cuspidati, 12g Pseudobulbus Bletillae (Rhizoma Bletillae), 18g Radix Ginseng, the 20g Rhizoma Atractylodis Macrocephalae, 15g Radix Sophorae Flavescentis, the 20g Radix Pulsatillae, 16g Caulis Spatholobi, 10g Radix Puerariae, 5g Pericarpium Citri Reticulatae and the 3g Radix Aucklandiae are mixed and pulverized; Mixture after pulverizing is added and in 1200g distilled water, soaks and decoct 3 times, decoct 1 hour at every turn, merging decoction liquor is also concentrated into thick shape; Adding subsequently concentration is 95% ethanol, fully stirring and evenly mixing, and being adjusted to alcohol content is 65%, precipitate 36 hours, filters acquisition the first alcoholic solution; It is 95% the abundant stirring and evenly mixing of ethanol that the first alcoholic solution is added to concentration again, and being adjusted to alcohol content is 75%, precipitates 36 hours, filters, and obtains the second alcoholic solution; The second alcoholic solution obtaining is concentrated into without alcohol taste, add 750g distilled water cold preservation precipitation 24 hours, filter, filtrate is concentrated, dry, pulverize, obtain 100 object graininess Chinese medicine composition 2 of the present invention, described Chinese medicine composition 2 is put into water and dissolve, stir acquisition oral liquid, crude drug amount 3g/ml.
Clinical experiment
Handan, Henan plant raises 1000 of laying hens, while raising to 23 age in days, occurs to be asthmoid respiration, breathes out, and necking down is air-breathing, discharges the disease that yellow green glue peptone shape feces is feature.Be chlamydia psittaci disease through laboratory diagnosis.After morbidity, adopted multi-medicament therapeutic effect undesirable, then used traditional Chinese medicine composition for treating of the present invention, all chickens have been fed by 5g dosage mixed feed, 5 days courses for the treatment of, be used in conjunction 7 weeks, medication after 5 days the state of an illness controlled.Final dead 80, cure 920, cure rate is 92%, follows up a case by regular visits to so far not recurrence.
Claims (2)
1. one kind is used for the treatment of the Chinese medicine composition of chlamydia psittaci disease, it is characterized in that, comprise: Radix Scutellariae, Rhizoma Osmundae, Fructus Mume, Fructus Forsythiae, Rhizoma Polygoni Cuspidati, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, Radix Sophorae Flavescentis, the Radix Pulsatillae, Caulis Spatholobi, Radix Puerariae, the parts by weight of the each component in described Chinese medicine composition are, Radix Scutellariae 65～75 weight portions, Rhizoma Osmundae 11～13 weight portions, Fructus Mume 30～35 weight portions, Fructus Forsythiae 25～30 weight portions, Rhizoma Polygoni Cuspidati 20～25 weight portions, Pseudobulbus Bletillae (Rhizoma Bletillae) 9～12 weight portions, Radix Ginseng 14～18 weight portions, the Rhizoma Atractylodis Macrocephalae 17～20 weight portions, Radix Sophorae Flavescentis 12～15 weight portions, the Radix Pulsatillae 16～20 weight portions, Caulis Spatholobi 12～16 weight portions, Radix Puerariae 7～10 weight portions, the described Chinese medicine composition that is used for the treatment of chlamydia psittaci disease is only made up of said components.
2. Chinese medicine composition as claimed in claim 1, is characterized in that: described Chinese medicine composition dosage form is decoction, powder, honey refining pill, hydration pill, tablet, capsule, oral liquid, granule, colloid or syrup.
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| CN103356794A (en) * | 2013-07-25 | 2013-10-23 | 天津必佳药业集团有限公司 | Traditional Chinese medicinal composition for controlling mycoplasma gallisepticum disease, and preparation method thereof |
| CN104920853A (en) * | 2015-06-09 | 2015-09-23 | 柳州市明达鸽业养殖专业合作社 | Feeding health-care sand for preventing and treating one-eye cold of meat pigeons |
| CN106620211A (en) * | 2016-12-05 | 2017-05-10 | 张明 | Traditional Chinese medicine composition for treating pigeon chlamydiosis |
| CN106728668A (en) * | 2016-12-05 | 2017-05-31 | 张明 | A kind of Chinese medicine composition for treating sheep chlamydiosis |
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| CN1245707A (en) * | 1999-08-12 | 2000-03-01 | 黄英秀 | Chinese medicine for curing AIDS and carcinomatosis |
| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
| CN101317904A (en) * | 2007-06-07 | 2008-12-10 | 何诚 | Uses of smoked plum extract against virus, bacteria, mycoplasma or chlamydia of livestock and poultry |
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