CN102973425A - Whitening anti-aging nanoscale skin-care agent - Google Patents
Whitening anti-aging nanoscale skin-care agent Download PDFInfo
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- CN102973425A CN102973425A CN2011102592630A CN201110259263A CN102973425A CN 102973425 A CN102973425 A CN 102973425A CN 2011102592630 A CN2011102592630 A CN 2011102592630A CN 201110259263 A CN201110259263 A CN 201110259263A CN 102973425 A CN102973425 A CN 102973425A
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- skin protectant
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- aging
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Abstract
The invention provides a whitening anti-aging nanoscale skin-care agent and its preparation method and use. The whitening anti-aging nanoscale skin-care agent comprises skin-care basic materials and additives and concretely comprises: by weight, 0.01 to 5% of a cell growth factor, 0.1 to 10% of collagen, 0.1 to 10% of hyaluronic acid, 0.01 to 5% of chondroitin sulfate, 0.01 to 3% of a nanoscale solution, 0.1 to 10% of arbutin, 0.1 to 10% of vitamin b5, and 0.1 to 10% of L-vitamin c. The whitening anti-aging nanoscale skin-care agent can improve a utilization rate of active ingredients of a whitening anti-aging skin-care product thereby realizing improvement of whitening and anti-aging effects. The whitening anti-aging nanoscale skin-care agent is safe and stable.
Description
Technical field
The present invention relates to skin protectant in a kind of human daily life and preparation method thereof, be specifically related to a kind of whitening anti-aging skin protectant and preparation method thereof and uses thereof.
Background technology
At present, the product that is used for beauty treatment, skin protection on the market is a lot, mainly comprises the products such as defying age, skin care, whitening.Environmental change and industrial pollution affect that caused skin aging, cortex are aging to these products for being subjected to, colour-darkening, tarnish etc. have the improvement effect.Yet, major part all is chemicals in these goods, water solublity is relatively poor, therefore need a large amount of or life-time service, could really effectively reach the whitening anti-aging effect, and owing to be chemicals, a large amount of or life-time service will certainly bring larger side effect, price is also expensive, is difficult to reach the target for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
Technical problem to be solved by this invention is for the deficiencies in the prior art, and a kind of whitening anti-aging skin protectant is provided, and can improve the utilization rate of whitening anti-aging skin care item effective ingredient, thereby reaches the purpose that improves the whitening anti-aging effect.The prescription of this skin protectant can reach best whitening anti-aging effect by the proportioning of science.
In order to solve the problems of the technologies described above, the present invention realizes by following technical scheme: skin protectant of the present invention is comprised of skin protection base material and additive, by the skin protectant total weight percent, additive comprises: cell growth factor 0.01%-5%, collagen protein 0.1%-10%, hyaluronic acid 0.1%-10%, chondroitin sulfate 0.01%-5%, nano fluid 0.01%-3%, arbutin 0.1%-10%, vitamin b5 0.1%-10%, L-vitamin c 0.1%-10%.
The preferred skin protectant of the present invention is comprised of skin protection base material and additive, by the skin protectant total weight percent, additive comprises: cell growth factor 0.01%-5%, collagen protein 0.1%-10%, hyaluronic acid 0.1%-10%, chondroitin sulfate 0.01%-5%, nano fluid 0.1%-3%, arbutin 0.1%-10%, vitamin b5 0.1%-10%, L-vitamin c 0.1%-10%.
The nano fluid preferred content is 3% in the skin protectant of the present invention.
Nano fluid is the polylactic acid emulsion in the skin protectant of the present invention.Be preferably the polylactic acid emulsion of particle diameter between 30-100nm.
Used base material comprises water and oil phase two parts among the present invention, wherein the oil phase raw material has vegetable and animals oils, mineral oil, aliphatic alcohol, polyol ester (sorbitol, spermol etc.), silicone oil, (content 2-23%) such as phospholipid (adenosine triphosphate), the water raw material has water-soluble polymer (Polyethylene Glycol, polyoxyethylene alcohol ester etc.), purifies waste water, (5-80%) such as quaternary amines (acetylamino oxypropyl trimethyl ammonium chloride), can add pH adjusting agent according to actual needs, surfactant (Pilus Caprae seu Ovis isopropyl fatty acid ester) (0.05-2%), spice (0.1-2%) etc.
Nano fluid is the polylactic acid emulsion of particle diameter between 30-100nm, and content is chosen in 0.01%-3%, preferred 0.1%-0.3%, more preferably 3%.
The present invention can be mixed with oil preparation on demand, Emulsion, unguentum, emulsion, facial film, milky lotion, cream etc.Be preferably emulsion, more preferably breast bag oil form.
Can invent can be for the preparation of cosmetics or topical agent.
The present invention is directed to that mechanism that wrinkle, pigment, mottle form adopts nano material and above-mentioned raw materials is composite forms, can finish efficiently the deep layer nursing to skin, accelerate the metabolism of skin, reparation is undermined keratinized skin, recover the elasticity of skin, thereby reach the effect of deep layer reduce wrinkle and skin whitening.
The present invention also provides a kind of skin protectant additive, it comprises: cell growth factor 0.01%-5%, collagen protein 0.1%-10%, hyaluronic acid 0.1%-10%, chondroitin sulfate 0.01%-5%, nano fluid 0.01%-3%, arbutin 0.1%-10%, vitamin b5 0.1%-10%, L-vitamin c 0.1%-10%.
Nano fluid content is 0.1%-3% in the preferred skin protectant additive of the present invention.
Nano fluid content is 3% in the preferred skin protectant additive of the present invention.
Nano fluid in the skin protectant additive of the present invention is the polylactic acid emulsion of particle diameter between 30-100nm.
The invention still further relates to the purposes of above-mentioned skin protectant additive in preparation whitening anti-aging skin protectant.
Another object of the present invention provides the preparation method of above-mentioned whitening anti-aging skin protectant.
Preparation method of the present invention: the water raw material is put into vessel in heating, stir; Then oil phase heating raw materials to fusing is stirred: the oil phase raw material is slowly added in the water raw material stir, during to room temperature, add antioxidant content and nano material, spice etc., stir, be mixed with on demand oil preparation, Emulsion in the preparation process, unguentum, emulsion, facial film, milky lotion, cream etc. namely get product.
Wherein, the heating-up temperature of water and oil phase is 65-90 ℃.
The specific embodiment
The applicant finds that through years of researches and experiment the pigment in the organism and the formation of wrinkle are dynamic continuously change procedures.All may form pigment and skin the part between the ribs and the hips vigor forfeiture phenomenon at different age brackets and different positions.The main cause of its formation is exactly the lipid peroxidation that caused by oxygen-derived free radicals, protein oxidation etc.In addition, the variation of external environment, as: air pollution, sunlight are exposed to the sun etc. and also can cause damage to organism.The present invention is directed to the formation mechanism of pigment and wrinkle, in skin-care product base, added as the nano material of effective ingredient carrier and had the active component of anti-oxidation function: cell growth factor 0.01%-5%, collagen protein 0.1%-10%, hyaluronic acid 0.1%-10%, chondroitin sulfate 0.01%-5%, nano fluid 0.01%-3%, arbutin 0.1%-10%, vitamin b5 0.1%-10%, L-vitamin c 0.1%-10%, hyaluronic acid 0.1%-10%.
Vitamin C, hyaluronic acid, collagen protein etc. are the cosmetic active raw material of natural origin.Can help skin to resist the ultraviolet infringement, avoid black speck, freckle to produce, enhance metabolism, allow established melanin discharge spot fading.Can also help skin to pin necessary moisture, avoid the decortication that causes because of too much evaporation and tight, strengthen the ability that skin opposing extraneous contamination is encroached on, avoid the skin peptide tired, wax yellow ugly; Hyaluronic acid has the total character of polysaccharide, has to draw moistly, and its loose, the molecular shape that expands can be in conjunction with a large amount of water, has moisturizing, moist effect, can protect effectively that the regenerative cell's is aging; Collagen protein is a kind of hmw protein, and thread collagen fabric can make skin keep solid and flexible, can see through horny layer and be combined with the skin epithelial cell, participates in and improve the metabolism of Skin Cell, makes active reinforcement of collagen protein in the skin.It can keep the integrity of horny layer moisture and fibre structure, improves the metabolism of Skin Cell living environment and promotion skin histology, strengthens blood circulation, reaches the purpose of skin care.
Embodiment
Describe the present invention in detail below in conjunction with embodiment, but do not limit scope of the present invention.
Embodiment one
| Component A | % by weight |
| Polyoxyethylene (20) ether tristerin | 5.0 |
| Cetyl stearic | 15 |
| Spermol | 3.0 |
| Semen Tritici aestivi germ oil | 2.0 |
| Polydimethylsiloxane | 0.3 |
| Propyl p-hydroxybenzoate | 0.02 |
| B component | |
| Glycerol | 3.0 |
| Deionized water | 56.68 |
| Component C | |
| Cell growth factor | 2.0 |
| Hyaluronic acid | 5.0 |
| Collagen protein | 2.0 |
| Chondroitin sulfate | 5.0 |
| Nano fluid | 3.0 |
Oil phase (component A) and water (B component) are heated to respectively 75 ℃, under stirring water are added oil phase, carry out emulsifying.Stir cooling.Add component C in the time of 35 ℃.In the time of 25 ℃ emulsion transferred in the suitable container, this moment, emulsion was stagnant condition, and viscosity reaches peak after several hours.
Embodiment two
Except the nano fluid percentage by weight is 0.01%, all the other components and content are identical with embodiment one, are prepared into emulsion.
Embodiment three
| Component A | % by weight |
| The pure and mild mineral oil mixture of Pilus Caprae seu Ovis fat | 5.0 |
| The Pilus Caprae seu Ovis isopropyl fatty acid ester | 1.0 |
| Mineral oil | 3.5 |
| Stearic acid | 1.5 |
| Tristerin | 2.0 |
| B component | |
| Glycerol | 3.0 |
| Polyacrylic acid 934,3% | 10.0 |
| Triethanolamine 10% | 10.00 |
| Deionized water | 37.00 |
| Component C | |
| Arbutin | 2.0 |
| Vitamin b5 | 5.0 |
| L-vitamin c | 2.0 |
| Hyaluronic acid | 5.0 |
| Nano fluid | 3.0 |
Oil phase (component A) and water (B component) are heated to respectively 75 ℃, under stirring component A oil phase are joined in the B component, stir cooling.Be cooled to room temperature, add component C.Transfer to subsequently in the suitable container this product of system.
Embodiment four
Except the nano fluid percentage by weight is 0.5%, all the other components and content are identical with embodiment three.
Embodiment five
Except the nano fluid percentage by weight is 0.1%, all the other components and content are identical with embodiment one.
Embodiment six
Hydroxyl radical free radical removing ability is measured
The configuration of experiment reagent
The phosphate buffer of pH=7.4: take by weighing 13.609gKH2PO4, the adding distil water dissolving is settled to 250ml, is A liquid; Take by weighing 45.644gK2HPO4, add water and be settled to 500mL, be B liquid.With volume ratio A: B=19: 81 ratio obtains pH=7.4 in configuration, the phosphate buffer solution of 0.2mol/L.
7.5mM FeSO4 solution: take by weighing 1.0428gFeSO47H2O, be settled to 500mL with dissolved in distilled water, obtain the solution that concentration is 7.5mM.
5mM Phen aqueous solution: take by weighing Phen 0.2478g, be settled to 250mL with distilled water, get the solution that concentration is 7.5mM.
1%H2O2 solution: the hydrogenperoxide steam generator with 30% dilutes 30 times and had both got 1% hydrogenperoxide steam generator.
Remove hydroxyl radical free radical OH
The phosphate buffered solution that adds respectively 2mL pH=7.4 in test tube, 0.3mL 5mM Phen solution fully behind the mixing, adds 0.2mL 7.5mM FeSO4 solution, whenever adds behind the pipe immediately mixing.Then to wherein add extracting solution, mixing adds 1% H2O21mL again, replenishes at last volume to 8mL.Do again in addition with the skin protectant protecting tube with the skin protectant protecting tube, respectively add again 1mL 1%H2O2 in the pipe, replenish at last each pipe volume to 8mL.In 37 ℃ of lower insulation 1h, survey the light absorption value under 536nm, calculate clearance rate, its computing formula is:
A1 is with the absorption value of skin protectant
A0 is not with the absorption value of skin protectant
The free radical scavenging effect of the application's skin care item part embodiment is as shown in the table:
The sample free radical scavenging activity
Embodiment one 25%
Embodiment 2 32%
Embodiment 3 33%
Embodiment 4 29%
| Embodiment five | 31％ |
Embodiment seven
Skin protectant treatment patient cases of the present invention is as follows:
Mr. Wang: 26 years old, people from Shijiazhuang, Hebei.The house ornamentation business is engaged in Tianjin, has a liking for tobacco and wine, partially has a liking for spicy.It is irregular to live, and causes the endocrine disturbance, causes the acne of face, and acne etc. have a strong impact on attractive in appearance.Adopt external of the present invention one course for the treatment of (external application 30 times, twice of every day), symptom takes an evident turn for the better, after continuing to use two courses for the treatment of, without recurrence.
Miss He: 41 years old, the Pekinese.Because of operating pressure, cause the endocrine disturbance, caused acne and butterfly spot etc., have a strong impact on attractive in appearance.After using the present invention course for the treatment of, symptom takes an evident turn for the better, and after continuing to use two twenty percents, cures without recurrence.
This product is through testing through Hygienic determination, and sanitary index meets 2007 editions " cosmetics health standard " regulation; The safety toxicological experiment shows and has no adverse effects.
Claims (24)
1. skin protectant, formed by skin protection base material and additive, it is characterized in that additive comprises by the skin protectant total weight percent: cell growth factor 0.01%-5%, collagen protein 0.1%-10%, hyaluronic acid 0.1%-10%, chondroitin sulfate 0.01%-5%, nano fluid 0.01%-3%, arbutin 0.1%-10%, vitamin b50.1%-10%, L-vitamin c 0.1%-10%.
2. the skin protectant in according to claim 1, wherein nano fluid content is 0.1%-3%.
3. the skin protectant in according to claim 1, wherein nano fluid content is 3%.
4. according to claim 1 skin protectant is characterized in that nano fluid is the polylactic acid emulsion.
5. according to claim 4 skin protectant is characterized in that nano fluid is the polylactic acid emulsion of particle diameter between 30-100nm.
6. the skin protectant in according to claim 1, base material wherein comprises water and oil phase.
7. the skin protectant in according to claim 6, in the base material wherein, oil phase content is 2-23%, aqueous phase content is 5-80%.
8. the skin protectant in according to claim 7, base material wherein also comprises pH adjusting agent, the surfactant of 0.05-2% and the spice of 0.1-2%.
9. according to claim 8 skin protectant, wherein surfactant is the Pilus Caprae seu Ovis isopropyl fatty acid ester.
10. according to claim 6 skin protectant, wherein the water raw material be selected from water-soluble polymer, purify waste water or quaternary amine in one or more.
11. skin protectant according to claim 10, wherein water-soluble polymer is Polyethylene Glycol and/or polyoxyethylene alcohol ester, and quaternary amine is acetylamino oxypropyl trimethyl ammonium chloride.
12. skin protectant according to claim 6, wherein the oil phase raw material is one or more in vegetable and animals oils, mineral oil, aliphatic alcohol, polyol ester, silicone oil or the phospholipid.
13. skin protectant according to claim 12, wherein polyol ester is sorbitol and/or spermol, and phospholipid is adenosine triphosphate.
14. skin protectant additive, it is characterized in that comprising: cell growth factor 0.01%-5%, collagen protein 0.1%-10%, hyaluronic acid 0.1%-10%, chondroitin sulfate 0.01%-5%, nano fluid 0.01%-3%, arbutin 0.1%-10%, vitamin b50.1%-10%, L-vitamin c0.1%-10%.
15. additive according to claim 14 is characterized in that nano fluid is the polylactic acid emulsion of particle diameter between 30-100nm.
16. skin protectant according to claim 1 is characterized in that its dosage form is oil preparation, Emulsion, unguentum, emulsion, facial film, milky lotion or cream.
17. skin protectant according to claim 1, it is emulsion.
18. skin protectant according to claim 1, it is O/w emulsion.
19. the preparation method of the skin protectant of claim 1 comprises: the water raw material is put into vessel in heating, stir; Then oil phase heating raw materials to fusing is stirred: the oil phase raw material is slowly added in the water raw material stir, during to room temperature, add antioxidant content and nano material, spice etc. stir, and prepare on demand different dosage form, namely get product.
20. the preparation method of claim 19, wherein said dosage form are oil preparation, Emulsion, unguentum, emulsion, facial film, milky lotion or cream.
21. the preparation method of claim 19, the heating-up temperature of water and oil phase are 65-90 ℃
22. the purposes of the skin protectant of claim 1 in preparation whitening anti-aging skin-protection product.
23. such as the purposes of claim 22, it is characterized in that the whitening anti-aging skin-protection product is cosmetics or topical agent.
24. the purposes of skin protectant additive in preparation whitening anti-aging skin protectant such as claim 14.
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| CN201110259263.0A CN102973425B (en) | 2011-09-05 | 2011-09-05 | A kind of whitening anti-aging nanoscale skin-care agent |
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| CN201110259263.0A CN102973425B (en) | 2011-09-05 | 2011-09-05 | A kind of whitening anti-aging nanoscale skin-care agent |
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| CN102973425B CN102973425B (en) | 2015-09-16 |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103202780A (en) * | 2013-04-16 | 2013-07-17 | 纪艺琼 | Nano essence for cosmetic and preparation method thereof |
| CN106389139A (en) * | 2016-11-22 | 2017-02-15 | 河南工业大学 | Acne-removing, mark-eliminating and skin-protecting multifunctional preparation and preparation method thereof |
| CN108066181A (en) * | 2017-12-18 | 2018-05-25 | 东莞俏美肌生物科技有限公司 | Whitening anti-aging skin conditioner |
| WO2018111626A3 (en) * | 2016-12-15 | 2018-07-26 | Elc Management Llc | Cosmetic compositions |
| CN110141533A (en) * | 2019-06-25 | 2019-08-20 | 吉林省华恩生物科技有限公司 | One kind going wrinkle Firm liquid and preparation method |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004002468A (en) * | 2003-08-11 | 2004-01-08 | Noevir Co Ltd | Eliminating agent of active-oxygen species |
| CN1736361A (en) * | 2005-08-03 | 2006-02-22 | 重庆师范大学 | Nanometer grade liposome aluminium lactates addictive for daily used chemical product |
| JP2007001924A (en) * | 2005-06-23 | 2007-01-11 | Oppen Keshohin Kk | Skin care preparation |
| CN101516327A (en) * | 2006-09-25 | 2009-08-26 | 纳幕尔杜邦公司 | Cosmetic compositions |
-
2011
- 2011-09-05 CN CN201110259263.0A patent/CN102973425B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004002468A (en) * | 2003-08-11 | 2004-01-08 | Noevir Co Ltd | Eliminating agent of active-oxygen species |
| JP2007001924A (en) * | 2005-06-23 | 2007-01-11 | Oppen Keshohin Kk | Skin care preparation |
| CN1736361A (en) * | 2005-08-03 | 2006-02-22 | 重庆师范大学 | Nanometer grade liposome aluminium lactates addictive for daily used chemical product |
| CN101516327A (en) * | 2006-09-25 | 2009-08-26 | 纳幕尔杜邦公司 | Cosmetic compositions |
Non-Patent Citations (6)
| Title |
|---|
| 丁克祥，等: "生物医药透皮传递系统在新型皮肤美容抗衰老系列功效纳米乳中的应用研究", 《第十二届东南亚地区医学美容学术大会论文汇编》 * |
| 丁克祥: "纳米技术在医学美容和抗衰老中的应用", 《第七届东南亚地区医学美容学术大会论文汇编》 * |
| 具熙宴，等: "《化妆品王国的秘密》", 30 April 2011, 商务印书馆国际有限公司 * |
| 吴继聪，等: "《美容医疗技术》", 31 March 2004, 科学出版社 * |
| 潘则林，等: "《水溶性高分子产品应用技术》", 28 February 2006, 化学工业出版社 * |
| 邱威扬，等: "《淀粉塑料——降解塑料研究与应用》", 31 March 2002, 化学工业出版社 * |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103202780A (en) * | 2013-04-16 | 2013-07-17 | 纪艺琼 | Nano essence for cosmetic and preparation method thereof |
| CN106389139A (en) * | 2016-11-22 | 2017-02-15 | 河南工业大学 | Acne-removing, mark-eliminating and skin-protecting multifunctional preparation and preparation method thereof |
| WO2018111626A3 (en) * | 2016-12-15 | 2018-07-26 | Elc Management Llc | Cosmetic compositions |
| US10660419B2 (en) | 2016-12-15 | 2020-05-26 | Elc Management Llc | Packaged skin treatment composition and method |
| US10660420B2 (en) | 2016-12-15 | 2020-05-26 | Elc Management Llc | Cosmetic compositions |
| US11291286B2 (en) | 2016-12-15 | 2022-04-05 | Elc Management Llc | Cosmetic compositions with a micro-mesh structure |
| CN108066181A (en) * | 2017-12-18 | 2018-05-25 | 东莞俏美肌生物科技有限公司 | Whitening anti-aging skin conditioner |
| CN110141533A (en) * | 2019-06-25 | 2019-08-20 | 吉林省华恩生物科技有限公司 | One kind going wrinkle Firm liquid and preparation method |
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| CN102973425B (en) | 2015-09-16 |
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