CN102970986B - 含有吡罗昔康的骨架型贴剂以及局部治疗急性和慢性疼痛及其相关炎症的方法 - Google Patents

含有吡罗昔康的骨架型贴剂以及局部治疗急性和慢性疼痛及其相关炎症的方法 Download PDF

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Publication number
CN102970986B
CN102970986B CN201180031485.5A CN201180031485A CN102970986B CN 102970986 B CN102970986 B CN 102970986B CN 201180031485 A CN201180031485 A CN 201180031485A CN 102970986 B CN102970986 B CN 102970986B
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CN
China
Prior art keywords
piroxicam
matrix type
autoadhesion
weight
casing play
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CN201180031485.5A
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English (en)
Chinese (zh)
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CN102970986A (zh
Inventor
王长金
埃里克·Y·许
南希·王
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Frontier Biotechnologies Co Ltd
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Nanjing Frontier Biotechnology Co ltd
Abbeth
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Publication of CN102970986A publication Critical patent/CN102970986A/zh
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN201180031485.5A 2010-05-27 2011-05-26 含有吡罗昔康的骨架型贴剂以及局部治疗急性和慢性疼痛及其相关炎症的方法 Active CN102970986B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39634710P 2010-05-27 2010-05-27
US61/396,347 2010-05-27
PCT/US2011/038189 WO2011150239A2 (en) 2010-05-27 2011-05-26 Piroxicam-containing matrix patches and methods for the topical treatment of acute and chronic pain and inflammation therewith

Publications (2)

Publication Number Publication Date
CN102970986A CN102970986A (zh) 2013-03-13
CN102970986B true CN102970986B (zh) 2015-06-03

Family

ID=44352274

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201180031485.5A Active CN102970986B (zh) 2010-05-27 2011-05-26 含有吡罗昔康的骨架型贴剂以及局部治疗急性和慢性疼痛及其相关炎症的方法

Country Status (7)

Country Link
US (2) US8563031B2 (https=)
EP (1) EP2575791B1 (https=)
JP (2) JP5948322B2 (https=)
CN (1) CN102970986B (https=)
AU (1) AU2011258146A1 (https=)
CA (1) CA2800716C (https=)
WO (1) WO2011150239A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3054931B1 (en) * 2013-10-07 2020-12-23 Teikoku Pharma USA, Inc. Transdermal delivery device for managing pain comprising dexmedetomidine transdermal compositions
TWI764951B (zh) 2016-10-31 2022-05-21 美商帝國製藥美國股份有限公司 用於處理疼痛之右美托咪啶經皮遞送裝置
CN107028921A (zh) * 2017-05-16 2017-08-11 蔡志浩 一种吡罗昔康巴布贴剂

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994023713A1 (en) * 1993-04-22 1994-10-27 Minnesota Mining And Manufacturing Company Transdermal antiinflammatory composition
US5904931A (en) * 1994-02-18 1999-05-18 Schering Aktiengesellschaft Transdermal therapeutic systems that contain sex steroids and dimethyl isosorbide
WO1999062557A1 (en) * 1998-06-02 1999-12-09 Lg Chemical Limited Composition for the transdermal administration of non-steroidal anti-inflammatory drugs
WO2005046654A1 (en) * 2003-11-17 2005-05-26 Icure Antiphlogistic and analgesic plaster comprising piroxicam compound

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5989586A (en) 1992-10-05 1999-11-23 Cygnus, Inc. Two-phase matrix for sustained release drug delivery device
ES2160623T3 (es) * 1992-12-31 2001-11-16 Sunkyong Ind Ltd Composiciones farmaceuticas mejoradas para la penetracion en la piel de piroxicam.
JP3305101B2 (ja) * 1994-03-29 2002-07-22 積水化学工業株式会社 経皮吸収製剤
JPH08295624A (ja) * 1995-04-26 1996-11-12 Read Chem Kk プラスター基剤、その製造方法、該基剤を使用した外用貼 付剤
EP1233763B1 (de) * 1999-11-29 2003-07-30 LTS Lohmann Therapie-Systeme AG Transdermale therapeutische systeme mit verbesserter stabilität und ein verfahren zu ihrer herstellung
US6645520B2 (en) * 1999-12-16 2003-11-11 Dermatrends, Inc. Transdermal administration of nonsteroidal anti-inflammatory drugs using hydroxide-releasing agents as permeation enhancers
BR0207955A (pt) 2001-03-07 2004-02-25 Hisamitsu Pharmaceutical Co Agente de emplastro
US20050020658A1 (en) * 2002-11-21 2005-01-27 Katsuyuki Inoo Selective cyclooxygenase-2 inhibitor patch
US20040127531A1 (en) * 2002-11-21 2004-07-01 Lu Guang Wei Adhesive coated sheet for dermal delivery of a selective cyclooxygenase-2 inhibitor
JP2007511544A (ja) * 2003-11-19 2007-05-10 アクルックス・ディ・ディ・エス・プロプライエタリー・リミテッド アミロイド症の予防若しくは治療のための組成物および方法
US20070196457A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Two or more volatile solvent-containing compositions and methods for dermal delivery of drugs
DE102004062614B4 (de) * 2004-12-24 2011-12-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit aktivierbarer Übersättigung und kontrollierter Permeationförderung sowie Verfahren zu dessen Herstellung
US20080226698A1 (en) * 2007-03-16 2008-09-18 Mylan Technologies, Inc. Amorphous drug transdermal systems, manufacturing methods, and stabilization
EP2676680A1 (de) * 2007-09-13 2013-12-25 Basf Se Verwendung von Hydrophobin-Polipeptiden als Penetrationsverstärker

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994023713A1 (en) * 1993-04-22 1994-10-27 Minnesota Mining And Manufacturing Company Transdermal antiinflammatory composition
US5904931A (en) * 1994-02-18 1999-05-18 Schering Aktiengesellschaft Transdermal therapeutic systems that contain sex steroids and dimethyl isosorbide
WO1999062557A1 (en) * 1998-06-02 1999-12-09 Lg Chemical Limited Composition for the transdermal administration of non-steroidal anti-inflammatory drugs
WO2005046654A1 (en) * 2003-11-17 2005-05-26 Icure Antiphlogistic and analgesic plaster comprising piroxicam compound

Also Published As

Publication number Publication date
WO2011150239A2 (en) 2011-12-01
US8563031B2 (en) 2013-10-22
US20110293721A1 (en) 2011-12-01
CA2800716A1 (en) 2011-12-01
AU2011258146A1 (en) 2012-12-20
US20140046274A1 (en) 2014-02-13
EP2575791B1 (en) 2018-08-08
CN102970986A (zh) 2013-03-13
JP5948322B2 (ja) 2016-07-06
EP2575791A2 (en) 2013-04-10
JP2016033163A (ja) 2016-03-10
JP2013527197A (ja) 2013-06-27
CA2800716C (en) 2019-11-05
WO2011150239A3 (en) 2012-06-07

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Free format text: FORMER OWNER: ABSIZE INC.

Effective date: 20150423

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Effective date of registration: 20150423

Address after: Jiangning District of Nanjing City, Jiangsu province 211122 Science Park Road No. 5 dry

Applicant after: Nanjing Frontier Biotechnologies Co., Ltd.

Address before: Osaka

Applicant before: ABsize Inc.

C14 Grant of patent or utility model
GR01 Patent grant
C53 Correction of patent of invention or patent application
CB03 Change of inventor or designer information

Inventor after: Wang Changjin

Inventor after: Sheu Eric Y.

Inventor after: Vuong Nancy

Inventor before: Wang Changjin

Inventor before: Sheu Eric Y.

Inventor before: Vuong Nancy

CP03 Change of name, title or address
CP03 Change of name, title or address

Address after: Jiangning District of Nanjing City, Jiangsu province 211122 Science Park Road No. 5 Building No. 7 dry (Zijin Mountain)

Patentee after: Frontier biopharmaceutical (Nanjing) Limited by Share Ltd

Address before: Jiangning District of Nanjing City, Jiangsu province 211122 Science Park Road No. 5 dry

Patentee before: Nanjing Frontier Biotechnologies Co., Ltd.