CN102948734A - Compound propolis soft-capsule for auxiliary reduction of blood sugar, and its preparation method - Google Patents
Compound propolis soft-capsule for auxiliary reduction of blood sugar, and its preparation method Download PDFInfo
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- CN102948734A CN102948734A CN2011102427154A CN201110242715A CN102948734A CN 102948734 A CN102948734 A CN 102948734A CN 2011102427154 A CN2011102427154 A CN 2011102427154A CN 201110242715 A CN201110242715 A CN 201110242715A CN 102948734 A CN102948734 A CN 102948734A
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Abstract
A compound propolis soft-capsule for the auxiliary reduction of the blood sugar is prepared from raw materials comprising propolis powder, American ginseng powder, Radix Ophiopogonis powder, rhodiola powder and fish oil. The preparation method of the compound propolis soft-capsule, which is carried out at room temperature, comprises the following steps: 1, mixing 25-35% of the propolis powder raw material filtered by a 120 mesh sieve with 10-20% of dry powder mixture raw materials comprising the American ginseng powder, the Radix Ophiopogonis powder and the rhodiola powder and filtered by a 100 mesh sieve; and 2, heating 50-55% of the fish oil to 50-70DEG C, adding the dry powder mixture obtained in step 1, uniformly stirring, and carrying out mechanical homogenization to obtain a homogenous ingredient. The compound propolis soft-capsule has the advantages of scientific composition, reasonable compatibility, simple technology, concentration of the effective components of all the raw materials, furthest preservation of the activities of all components, performance of the coordination, integration and reinforcement effects among all the components, and obvious and effective adjust effect on the blood sugar.
Description
Technical field
The present invention relates to field of health care food, espespecially a kind of auxiliary hyperglycemic compound bee-glue soft capsule and preparation method thereof.
Background technology
Propolis
1. propolis is a kind of very strong natural, and can significantly improve human body SOD(superoxide dismutase) activity.The negative nineteen ninety-five proposition of the red plumage of the famous doctor of medicine of Japan, the interior too much free radical of body and lipid peroxide and onset diabetes are closely related, and it is that free radical and lipid peroxide cause that quite a few diabetes is arranged.There are some researches prove, with antioxidant (SOD) treatment diabetes have 50%～60% efficient.
2. there are some researches prove flavonoids
Terpenoid substance has the effect that promotes to utilize the synthetic hepatic glycogen of exogenous glucose, and this class material has and obviously falls hypoglycemic effect.Pharmacological research and clinical observation are found
The Flavonoid substances of propolis extract rich content, terpenoid substance diabetes rat and diabetic are all had obvious hypoglycemic effect, and the course for the treatment of are longer, and hypoglycemic effect is better.
3. in fact, it is the blood sugar reducing function of propolis that the most important significance of propolis treatment diabetes has more than, but the complex treatment effect of Propolis on Diabetes Mellitus, particularly propolis can prevent and treat various infection, can softening blood vessel, purify blood vessel, improve microcirculation, the generation of prevention cardiovascular and cerebrovascular complication.
American Ginseng
[meridian distribution of property and flavor] sweet, little hardship, cold.The thoughts of returning home, lung, kidney channel.
[function cures mainly] boosting qi and nourishing yin, clearing heat and promoting fluid.It is thanks to cloudy to be used for the deficiency of vital energy, and interior heat is coughed and breathed heavily phlegm blood, and abnormal heat is tired tired, quenches one's thirst dryness of the mouth and throat.American Ginseng has antifatigue, anti-oxidant, the anti-effect that stress, suppress platelet aggregation, reduces blood clotting, in addition, can reduce blood sugar, regulates insulin secretion, promote glycometabolism and fat metabolism that the treatment diabetes are had certain booster action.
[assay] ginsenoside Rb1, Rg1, Re total amount＞2.0%
3. rhodiola root
[meridian distribution of property and flavor] is sweet, and hardship is flat.Return lung, the heart channel of Hang-Shaoyin.
[function with cure mainly] qi and activate blood circulation is promoted blood circulation and is relievingd asthma.Be used for qi deficiency to blood stasis, chest impediment and cardialgia, hemiplegia, burnout asthma.Clinical practice improves muscle power and the illnesss such as mental labour function, neurosis, hypotony syndrome, diabetes and anaemia in antifatigue.
[significant component content mensuration] rhodioside＞0.50%
4. tuber of dwarf lilyturf
[meridian distribution of property and flavor] is sweet, and little hardship is slightly cold.The thoughts of returning home, lung, stomach warp.。
[function with cure mainly] nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire.Be used for dryness of the lung dry cough.The consumptive disease cough, Tianjin wound is thirsty, vexed insomnia, interior heat is quenched one's thirst, the dry constipation of intestines; Pharyngeal diphtheria.Control dryness of the lung dry cough, spit blood, spitting of blood, consumptive lung disease, lung carbuncle, the consumptive disease dysphoria with smothery sensation is quenched one's thirst, and hinder in pyreticosis Tianjin, dry throat, constipation.Clinical practice is in improving immunologic function; Various bacteria there is inhibitory action; Can strengthen the pituitary adrenal system function, improve the organism adaptation ability; Anti-arrhythmia and the peripheral vascular effect of expansion are arranged; Can improve hypoxia-bearing capability; Hypoglycemic activity is arranged.
Mainly contain the compositions such as ophiopogonin class, osajin and glutinous polysaccharide [significant composition] tuber of dwarf lilyturf.1. saponins: contain Ophiopogonin A, B, C, D, its aglycon is the Lu Sikao sapogenin; Ophiopogonin B ', C', D', be steroid saponin, its aglycon is diosgenin.2. osajin: contain methylophiopogonanone first, second, methylophippogonone first, second, different tuber of dwarf lilyturf the ketone first, demethyl ketone tuber of dwarf lilyturf second, ophiopogonanone the second grade.3. glutinous polysaccharide: contain ophiopogonoligosaccharide A, B, C, the tuber of dwarf lilyturf polysaccharide etc.4. contain the compositions such as cupreol, stigmasterol.
5. fish oil
[effect] invigorates blood circulation; Lipopenicillinase
[function with cure mainly] research thinks that the Ω in the deep sea fish oil-3 polyunsaturated fat is recognized as has the effect that reduces cholesterol, so the deep sea fish oil capsule has splendid health care to be worth.The effect of deep sea fish oil is worth and also is embodied among the EPA and DHA content of a large amount.The EPA that deep sea fish oil contains and DHA belong to Ω-3 polyunsaturated fatty acid, are that people self can't synthesize but necessary important component.EPA popular name blood vessel street cleaner in the deep sea fish oil capsule, but thereby reducing blood lipid, prevention of arterial is atherosis prevention cardiovascular and cerebrovascular disease also has hypotensive effect by the protection to blood vessel and heart; DHA popular name " docosapentaenoic acid " mainly is present in people's brain, activating brain cell is arranged, strengthen memory, delays brain aging, strengthens the effect that cranial nerve sensitivity and information are passed on speed.
[significant composition] EPA---guard blood circulation.EPA is the english abbreviation of eicosapentaenoic acid, it is a kind of special unrighted acid, have many sanguimotor protection factors that are of value to, comprise: (1) assists obese patient, hypertension, hyperlipemic patients, the flowability that keeps blood level, suppress undesired blood aggegation, the generation of pre-preventing thrombosis is with the generation of apoplexy and miocardial infarction; (2) assist to remove cholesterol and the harden plaque that is attached on the vascular wall, cholesterol bad in the blood is descended, to keep the good elasticity of blood vessel and permeability; (3) assist the bad people's (comprising high triglyceride patient and diabetic) of fat metabolism, reduce triglyceride and avoid fat accumulation, and then the generation that prevention of arterial hardens, peripheral vessel blocks the situations such as destruction.DHA---activating brain cell, healthy good eyesight.DHA is the english abbreviation of DHA, is another kind of special unrighted acid, has the clever factor of activating brain cell.Have approximately 10% to be the DHA composition in the fat of adult's brain, scientist finds to contain a large amount of DHA compositions in " the neurite cell " of brain, so that the nerve conduction substance of brain is than being easier to conduct correct message.Therefore DHA institute role is: promote, coordinate the nerve conduction effect, keeping the normal operation of brain cell, thereby improve concentrated force, memory, notice and understandability.
Summary of the invention
The objective of the invention is to provide a kind of compound bee-glue soft capsule prescription of auxiliary hyperglycemic, this prescription relates to multiple traditional Chinese medicine material, his proportioning has been preserved the activity of various compositions to greatest extent, coordination between each composition, comprehensive and booster action have been brought into play, blood sugar is had obvious and effective regulating action, and safety has no side effect.
The present invention is achieved in that a kind of auxiliary hyperglycemic compound bee-glue soft capsule is comprised of following component by weight percentage to achieve the above object: bee glue powder accounting 25%-35%, ginseng, the tuber of dwarf lilyturf, rhodiola root mixture dry powder accounting 10%-20%, fish oil accounting 50%-55%.
The method of the compound bee-glue soft capsule of a kind of auxiliary hyperglycemic of preparation provided by the invention may further comprise the steps: each step is all carried out at ambient temperature.
(1) 25%-35% is crossed 120 mesh sieves the refined propolis powder raw material, mix with ginseng, the tuber of dwarf lilyturf, rhodiola root mixture dry powder raw material that 10%-20% crosses 100 mesh sieves;
(2) 50%-55% fish oil is heated to 50-70 ℃, adds suspending agent, drop into again the powder mixture in the step 1, stir, and use mechanical homogeneous, obtain the homogeneous batching;
The homogeneous batching of (3) step 2 being made is carried out pill as content.
Advantage of the present invention: this prescription relates to multiple traditional Chinese medicine material, and his proportioning has been preserved the activity of various compositions to greatest extent, has brought into play coordination between each composition, comprehensive and booster action, and blood sugar is had obvious and effective regulating action; And processing technology is simple; Safe without toxic side effect.
Description of drawings
Fig. 1 is a kind of auxiliary hyperglycemic compound bee-glue of the present invention soft capsule preparation method's schematic flow sheet.
The specific embodiment
The below is further elaborated a kind of auxiliary hyperglycemic compound bee-glue of the present invention soft capsule and preparation method thereof.
Embodiment: a kind of auxiliary hyperglycemic compound bee-glue of the present invention soft capsule is pressed following percentage by weight formulated:
Bee glue powder 30%;
Ginseng powder 10%;
Ophiopogon powder 5%;
Rhodiola root powder 5%;
Fish oil 50%.
Check and accept bee glue powder, ginseng powder, ophiopogon powder, rhodiola root powder, fish oil according to the material quality acceptance requirement, take by weighing bee glue powder 3.0 kg according to the raw material weight ratio; Ginseng powder 1.0 kg, ophiopogon powder 0.5 kg, rhodiola root powder 0.5 kg; Fish oil 5.0 kg.
The preparation method is as follows:
(1) with the 30% refined propolis powder raw material that has filtered through 120 mesh sieves with through the filtration of 120 mesh sieves 10% ginseng, 5% tuber of dwarf lilyturf, 5% rhodiola root mixture dry powder raw material mix;
(2) 50% fish oil is heated to 50-70 ℃, drops into again the powder mixture in the step 1, stir, and use mechanical homogeneous, obtain the homogeneous batching;
(3) carry out pill, wash ball etc. and make bee glue soft capsule according to soft capsule dosage form technique.
Above-mentioned steps is all carried out at ambient temperature.
The present invention has preserved the activity of propolis, ginseng, the tuber of dwarf lilyturf, rhodiola root, the various compositions of fish oil to greatest extent, brought into play between each composition coordinate, comprehensive and booster action, blood sugar had obvious and effective regulating action, and safe having no side effect.
Claims (2)
1. auxiliary hyperglycemic compound bee-glue soft capsule is characterized in that being made by following percentage by weight raw material:
Bee glue powder 25%-35%;
Ginseng, the tuber of dwarf lilyturf, rhodiola root mixture dry powder 10%-20%;
Fish oil 50%-55%.
2. auxiliary hyperglycemic compound bee-glue soft capsule according to claim 1, its preparation method may further comprise the steps:
(1) the refined propolis powder raw material that 25%-35% has been filtered through 120 mesh sieves and 10%-20% through the filtration of 100 mesh sieves ginseng, the tuber of dwarf lilyturf, rhodiola root mixture dry powder raw material mix;
(2) 50%-55% fish oil is heated to 50-70 ℃, drops into again the powder mixture in the step 1, stir, and use mechanical homogeneous, obtain the homogeneous batching;
(3) carry out pill, wash ball etc. and make bee glue soft capsule according to soft capsule dosage form technique;
Above-mentioned steps is all carried out at ambient temperature.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2011102427154A CN102948734A (en) | 2011-08-23 | 2011-08-23 | Compound propolis soft-capsule for auxiliary reduction of blood sugar, and its preparation method |
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| CN2011102427154A CN102948734A (en) | 2011-08-23 | 2011-08-23 | Compound propolis soft-capsule for auxiliary reduction of blood sugar, and its preparation method |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105192699A (en) * | 2015-09-30 | 2015-12-30 | 深圳市生命力生物保健科技江苏有限公司 | Fish oil soft capsules and preparation method thereof |
| CN114642676A (en) * | 2020-12-18 | 2022-06-21 | 中国科学院上海营养与健康研究所 | Application of ginsenoside in improving intestinal flora structure and/or intestinal barrier function |
Citations (4)
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| CN1568760A (en) * | 2004-05-11 | 2005-01-26 | 浙江蜂之语蜂业集团有限公司 | Propolis soft capsule |
| CN101199554A (en) * | 2007-12-24 | 2008-06-18 | 中国农业科学院蜜蜂研究所 | Oil-soluble propolis soft capsule and preparing method thereof |
| CN101513429A (en) * | 2008-02-18 | 2009-08-26 | 武汉枫叶红生物科技有限公司 | Composition capable of improving blood and sugar metabolism function and preparation method thereof |
| CN101912111A (en) * | 2010-07-19 | 2010-12-15 | 马建中 | Method for preparing high-content propolis soft capsules |
-
2011
- 2011-08-23 CN CN2011102427154A patent/CN102948734A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1568760A (en) * | 2004-05-11 | 2005-01-26 | 浙江蜂之语蜂业集团有限公司 | Propolis soft capsule |
| CN101199554A (en) * | 2007-12-24 | 2008-06-18 | 中国农业科学院蜜蜂研究所 | Oil-soluble propolis soft capsule and preparing method thereof |
| CN101513429A (en) * | 2008-02-18 | 2009-08-26 | 武汉枫叶红生物科技有限公司 | Composition capable of improving blood and sugar metabolism function and preparation method thereof |
| CN101912111A (en) * | 2010-07-19 | 2010-12-15 | 马建中 | Method for preparing high-content propolis soft capsules |
Non-Patent Citations (2)
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| 无: ""降糖 携样 延年三步远离糖尿病"", 《养生大世界》, no. 06, 31 December 2007 (2007-12-31) * |
| 李维林等: ""糖尿病治疗中常用的中草药"", 《药用植物研究与中药现代化——第四届全国药用植物学与植物药学术研讨会论文集》, 31 October 2004 (2004-10-31) * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105192699A (en) * | 2015-09-30 | 2015-12-30 | 深圳市生命力生物保健科技江苏有限公司 | Fish oil soft capsules and preparation method thereof |
| CN114642676A (en) * | 2020-12-18 | 2022-06-21 | 中国科学院上海营养与健康研究所 | Application of ginsenoside in improving intestinal flora structure and/or intestinal barrier function |
| WO2022127934A1 (en) * | 2020-12-18 | 2022-06-23 | 中国科学院上海营养与健康研究所 | Use of ginsenoside in improving intestinal bacterial flora structure and/or intestinal barrier function |
| CN114642676B (en) * | 2020-12-18 | 2024-02-13 | 中国科学院上海营养与健康研究所 | Application of ginsenoside in improving intestinal flora structure and/or intestinal barrier function |
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Application publication date: 20130306 |