CN102258686B - Chinese medicinal preparation for preventing and treating cardiovascular and cerebrovascular diseases - Google Patents
Chinese medicinal preparation for preventing and treating cardiovascular and cerebrovascular diseases Download PDFInfo
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- CN102258686B CN102258686B CN201110190949A CN201110190949A CN102258686B CN 102258686 B CN102258686 B CN 102258686B CN 201110190949 A CN201110190949 A CN 201110190949A CN 201110190949 A CN201110190949 A CN 201110190949A CN 102258686 B CN102258686 B CN 102258686B
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Abstract
The invention provides a Chinese medicinal preparation for preventing and treating cardiovascular and cerebrovascular diseases, which has an obvious curative effect. The Chinese medicinal preparation is prepared from the following raw materials in part by weight: 1.5 to 5 parts of leech, 1 to 6 parts of notoginseng root, 2 to 15 parts of Siberian solomonseal rhizome, 2 to 9 parts of earthworm, 2 to 9 parts of American ginseng and 0.2 to 3 parts of cassia bark. The Chinese medicinal preparation can be prepared into decoction, capsules and the like by the conventional method. The Chinese medicinal preparation has the effects of reducing blood fat, resisting coagulation, dissolving thrombus, reducing blood pressure and benefiting lung, spleen and kidney, can enhance immunity, prevent diseases and treat the cardiovascular and cerebrovascular diseases, is low in cost, solves the problem of multiple medicines and has a good clinical effect.
Description
Technical field
The present invention relates to a kind of medicine, specifically is the Chinese medicine preparation of a kind of prevention and treatment cardiovascular and cerebrovascular disease.
Background technology
Cardiovascular and cerebrovascular disease is exactly cardiovascular and cerebrovascular disease general designation.Change along with growth in the living standard and rhythm of life; " three-hypers disease " (being hypertension, hyperglycemia and hyperlipidemia) that is called as " affluenza "; Hypertensive old people uses depressor to be worthy of careful study, and principle is arranged, for the selection of old depressor; With advancing age, the hypertension prevalence increases gradually.40%～45% suffer from hypertensive also suffer from simultaneously hyperglycemia or hyperlipidemia among the old people more than 60 years old; Show according to Ministry of Public Health statistics in 2007; Show that according to external data about 50% diabetes patient is associated with multiple infirmitiess of age such as hypertension, hyperlipidemia.The cardiovascular and cerebrovascular disease sickness rate is higher at present, and to younger development, clinical application is various, and patient's medication is few more than the 2-3 kind.The medicine of prevention of using at present and treatment cardiovascular and cerebrovascular disease exists also that curative effect is relatively poor, medication is many, treat the high shortcoming of cost.
Summary of the invention
Technical problem to be solved by this invention provides a kind of prevention evident in efficacy and the Chinese medicine preparation of treatment cardiovascular and cerebrovascular disease.
Address the above problem, the technical scheme that the present invention adopts is: the Chinese medicine preparation of a kind of prevention and treatment cardiovascular and cerebrovascular disease, process Hirudo 1.5-5, Radix Notoginseng 1-6, Rhizoma Polygonati 2-15, Pheretima 2-9, Radix Panacis Quinquefolii 2-9, Cortex Cinnamomi 0.2-3 by the raw material of following parts by weight.Can process decoct with conventional method, capsule etc.
Side of the present invention separates:
1, Hirudo is processed salty, bitter, flat.By the stagnant blood blood stasis, removing blood stasis disease is gathered, dredging water passages.Salty flavor acting on blood, the bitter blood that wins, the salty hardship of Hirudo to remove poultry blood, is a Liver Channel blood system medicine, gathers blood so can lead to Liver Channel.Modern medicine is reported for work: (1), blood coagulation resisting function: prevent the effect of blood coagulation.(2), anti-thrombolytic effect: Hirudo have antiplatelet aggregation and the formed thrombosis effect of dissolving thrombin, the external in vivo effect that the activation fibrinolytic system is all arranged.(3), effect for reducing fat: Hirudo powder 1g/, the white mouse test all can make cholesterol and triglyceride content reduce.(4), strengthen the myocardial nutritional flow effect.(5), decoct 2.5-3/ kilogram, alleviate around the cephalophyma inflammation and edema is alleviated, intracranial pressure raises exempts from necrosis and promote neurological functional recovery.
2, the sweet little hardship of Radix Notoginseng is warm, nontoxic.The analgesic therapy of styptic powder blood, blood stasis is not stayed in hemostasis, and fresh blood is not hindered in promoting the circulation of blood, blood stasis dispelling and tissue regeneration promoting blood, blood stasis dispelling and unlikely hemorrhage.Temperature, sweet and slightly bitter taste is that sun is bright, the medicine of the cloudy blood system of fainting.
Modern medicine report: (1), blood vessel dilating, the microcirculation improvement blood flow increasing that brings high blood pressure down prevention and treated tissue hypoxic-ischemic disease.(2), promote protein core ribosomal ribonucleic acid, DNA to synthesize building body.(3), promote blood cell metabolism, balance adjustment hemocyte.(4), the two-ways regulation nervus centralis improves brain function.(5), enhancing human body immunity power, antitumor.
3, Rhizoma Polygonati (processing): sweet, flat, nontoxic.The invigorating middle warmer yin nourishing, spleen invigorating lung moistening kidney tonifying.Remove rheumatism, settling five organs, for a long time clothes make light of one's life by commiting suicide prolong life not hungry.Mend five kinds of strain and seven kinds of impairment, help the muscles and bones summer-heat that resist cold, the strengthening the spleen stomach moistens cardiopulmonary, returns spleen lung kidney channel.The mother of soil person's all things on earth, female that it is supported, then coordinating water and fire, wooden gold is joined and is gone certainly at evil, and all kinds of diseases and ailments are not given birth to.Rhizoma Polygonati alleviating distention in middle-JIAO QI invigorating, it is good that the five internal organs are transferred, muscle sufficiency, bone marrow is strong, its power multiplication, the merit of rejuvenation.
4, Pheretima: salty in the mouth, cold main return liver, spleen, urinary bladder channel.Have clearing away heat and relieving the wind syndrome, suppressing the hyperactive liver, dredge the meridian passage, excessive rising of liver-YANG, apoplectic hemiplegia.
5, Radix Panacis Quinquefolii: cool, mind calming Fructus Alpiniae Oxyphyllae, nourishing YIN and moistening the lung, the heat clearing away fire, the modern medicine report: it is with all worries set aside with fixed attention that (1) strengthens central nervous system function (Saponin), allaying tiredness, hypermnesis.(2) protection cardiovascular, blood pressure regulation helps recoveries such as hypertension, arrhythmia, coronary heart disease, acute myocardial infarction, cerebral thrombosis.(3) promote the blood flow vigor, reduce blood coagulation.
6, Cortex Cinnamomi: hot, sweet, big heat.Return kidney spleen, conscience warp.It is supporing yang to mend fire, let the fire back to its origin promoting blood circulation to remove obstruction in the collateral, complement sun, warming the spleen and stomach.Obey for a long time in case all medicines are cold partially, cold injures sun with this medicine.
As a kind of preferred scheme, process decoct by the raw material of following parts by weight, Hirudo 3-5 part, Radix Notoginseng 5-6, Rhizoma Polygonati 9-15, Pheretima 6-9, Radix Panacis Quinquefolii 6-9, Cortex Cinnamomi 1-3; To add proper amount of clear water during preparation and soak after 30 minutes, and add in the decocting medicine pot and fried in shallow oil 25-30 minute, temperature keeps about 100 ℃, and filtering residue promptly gets then.
As the preferred scheme of another kind, process capsule by the raw material of following parts by weight, Hirudo 1.5-3 part, Radix Notoginseng 1-3, Rhizoma Polygonati 2-5, Pheretima 2-3, Radix Panacis Quinquefolii 2-4, Cortex Cinnamomi 0.2-0.5; During preparation earlier with above material processing, pulverizing, cross that to mix the back behind the 80-100 mesh sieve encapsulated.
Raw material is got ready by prescription, presses Pharmacopoea Chinensis and concocts, concrete concocting process:
1, Hirudo: by prescription consumption water intaking trematodiasis, get Pulvis Talci, Hirudo and Pulvis Talci proportion are 5:2, and Pulvis Talci is put into a pot internal heating, drop into the Hirudo section when being heated to flexible state, spare no effort to stir, and fry to little heaving, and take out when being yellowish-brown, sieve and remove Pulvis Talci, cool;
2, Radix Notoginseng: get raw material, remove impurity, be ground into fine powder;
3, Rhizoma Polygonati: get clean Rhizoma Polygonati, clean, steam, take out chip drying when moistening to brownish black;
4, Pheretima: get pure land dragon section, add a small amount of yellow wine and mix thoroughly and run through, fry with slow fire and do, take out airing when the surface is brown;
5, Radix Panacis Quinquefolii: get raw material and remove the impurity section;
6, Cortex Cinnamomi is got raw material and removes the impurity segmentation.
Model case:
1. Xue Li door, the man, 59 years old is west, Xiangning County village people with one voice, occupation: the doctor, go to a doctor on June 16th, 2009, conscious Light-headedness, nervous sometimes.Have a blood test and press 130/90mmHg, electrocardiogram is normal.Plasma viscosity 4.66 (reference value 1.26-1.66), cholesterolemia 8.20 (reference value 3.4-5.9), surplus the bimester of obeying this prescription (capsule), transference cure, the fat of having a blood test, blood viscosity are normal.
2. poplar Zhenglin, man, 54 years old; Be the grand rich company technique person in Xiangning County, go to a doctor that it is surplus to have suffered from coronary heart disease 3 years on March 12nd, 2009; Take aspirin class, Radix Salviae Miltiorrhizae Tabellae, sorbitrate, FENOBRATE top grade medicine at ordinary times, but every day working nervously breathe hard, weak, conscious deficient in energy.Change these sides of clothes (decoct) surplus in the of ten dose after sx, after surplus transference cure use this side's capsule again instead and take the bimester.So far keep inspection (patient does not go for) such as do not have an electro-cardiogram with capsule.
3. left hall dragon, the man, 75 years old is Fructus Jujubae mountain range, Xiangning County village people.The people went to a doctor April 18 in 2006; Cause giddy in three months, speech disorder, unstable, the numb hand and foot of walking; The forth academy is diagnosed as cerebral infarction in Linfen, and through transfusion blood circulation promoting medicines such as () Radix Salviae Miltiorrhizae Injectiones, curative effect of medication such as oral NAOXINTONG, aspirin class, Radix Salviae Miltiorrhizae Tabellae are very dissatisfied; Change this side of clothes and observe the symptoms over three months and alleviate gradually, take that subjective symptoms fades away after five months.
4. grandson builds roc, the man, and 48 years old is Xi Po people from town, Xiangning County.Ceng Yintou pain, dizzy the 4th medical officer's thorough examination (spiral CT) in Xi'an, left neck artery has a speckle, take this side (capsule) 8 months surplus after, check speckle and dwindle.
5. Li Wenying, the woman, 69 years old, the west, Xiangning County is township Yang Ta people from village with one voice.In on the JIUYUE 13rd, 2010 of 2 conscious Upper abdominal paines in the left and right sides, perspiration at night.Plan is examined angina pectoris.Anxious water intaking trematodiasis, Radix Notoginseng are that take at the end, get this side's decoct again and take the back pain relief, and sending the county town hospital diagnosis is coronary heart disease, leave hospital in a week (because of economy is not propped up) in hospital, and oral this side in back does not see recurrence so far.
The present invention has following beneficial effect: (1) has the effect of blood fat reducing, anticoagulant, thrombolytic, blood pressure lowering, lung benefiting, spleen, kidney, and both the enhance immunity prevent disease can be treated cardiovascular and cerebrovascular disease again.(2) reduce drug cost, reduce many loaded down with trivial details of medication, clinical effectiveness is preferably arranged, through 150 routine clinical preliminary observations, cure rate reaches more than 90%, and effective percentage has reduced toxic and side effects more than 95% simultaneously.Several 94 examples of the total example of hyperlipidemia, effective 94 examples, effective percentage 100%; Several 45 examples of the total example of hypertension, effective 42 examples, effective percentage 95%; Several 6 examples of the total example of coronary heart disease, effective 6 examples, effective percentage 100%; Cerebral infarction, several 65 examples of the total example of cerebral thrombosis, effective 65 examples, effective percentage 100%; Several 1 examples of the total example of carotid atherosclerotic plaque, effective 1 example, effective percentage 100%.
The specific embodiment
Embodiment 1
Raw material: Hirudo 3 grams, Radix Notoginseng 5 grams, Rhizoma Polygonati 9 grams, Pheretima 6 grams, Radix Panacis Quinquefolii 6 grams, Cortex Cinnamomi gram.
Method for preparing: above raw material is concocted by above-mentioned manufacturing process, added proper amount of clear water and soak after 30 minutes, add in the decocting medicine pot and fried in shallow oil 25-30 minute; Temperature keeps about 100 ℃; Filtering residue then, medicinal liquid are packed in the packaging bag, put into autoclave up 15 minutes; 1.5 pounds of pressure, storage temperature is below 8 ℃.
Embodiment 2
Raw material: Hirudo 5 grams, Radix Notoginseng 6 grams, Rhizoma Polygonati 15 grams, Pheretima 9 grams, Radix Panacis Quinquefolii 9 grams, Cortex Cinnamomi 3 grams.
Method for preparing: above raw material is concocted by above-mentioned manufacturing process, added proper amount of clear water and soak after 30 minutes, add in the decocting medicine pot and fried in shallow oil 25-30 minute; Temperature keeps about 100 ℃; Filtering residue then, medicinal liquid are packed in the packaging bag, put into autoclave up 15 minutes; 1.5 pounds of pressure, storage temperature is below 8 ℃.
Embodiment 3
Raw material: Hirudo 4 grams, Radix Notoginseng 5.5 grams, Rhizoma Polygonati 12 grams, Pheretima 8 grams, Radix Panacis Quinquefolii 7 grams, Cortex Cinnamomi 2 grams.
Method for preparing: above raw material is concocted by above-mentioned manufacturing process, added proper amount of clear water and soak after 30 minutes, add in the decocting medicine pot and fried in shallow oil 25-30 minute; Temperature keeps about 100 ℃; Filtering residue then, medicinal liquid are packed in the packaging bag, put into autoclave up 15 minutes; 1.5 pounds of pressure, storage temperature is below 8 ℃.
Embodiment 4
Raw material: Hirudo 3 grams, Radix Notoginseng 5.5 grams, Rhizoma Polygonati 15 grams, Pheretima 8 grams, Radix Panacis Quinquefolii 8 grams, Cortex Cinnamomi 3 grams.
Method for preparing: above raw material is concocted by above-mentioned manufacturing process, added proper amount of clear water and soak after 30 minutes, add in the decocting medicine pot and fried in shallow oil 25-30 minute; Temperature keeps about 100 ℃; Filtering residue then, medicinal liquid are packed in the packaging bag, put into autoclave up 15 minutes; 1.5 pounds of pressure, storage temperature is below 8 ℃.
Embodiment 5
Raw material: Hirudo 1.5 grams, Radix Notoginseng 1 gram, Rhizoma Polygonati 2 grams, Pheretima 2 grams, Radix Panacis Quinquefolii 2 grams, Cortex Cinnamomi 0.2 gram;
Method for preparing: earlier with above material processing, pulverizing, cross that to mix the back behind the 80-100 mesh sieve encapsulated.
Embodiment 6
Raw material: Hirudo 3 grams, Radix Notoginseng 3 grams, Rhizoma Polygonati 5 grams, Pheretima 3 grams, Radix Panacis Quinquefolii 4 grams, Cortex Cinnamomi 0.5 gram.
Method for preparing: earlier with above material processing, pulverizing, cross that to mix the back behind the 80-100 mesh sieve encapsulated.
Embodiment 7
Raw material: Hirudo 2 grams, Radix Notoginseng 3 grams, Rhizoma Polygonati 4 grams, Pheretima 2.5 grams, Radix Panacis Quinquefolii 3 grams, Cortex Cinnamomi 0.4 gram.
Method for preparing: earlier with above material processing, pulverizing, cross that to mix the back behind the 80-100 mesh sieve encapsulated.
Embodiment 8
Raw material: Hirudo 3 grams, Radix Notoginseng 1 gram, Rhizoma Polygonati 4 grams, Pheretima 2 grams, Radix Panacis Quinquefolii 3 grams, Cortex Cinnamomi 0.2 gram.
Method for preparing: earlier with above material processing, pulverizing, cross that to mix the back behind the 80-100 mesh sieve encapsulated.
Claims (3)
- One kind the prevention and the treatment cardiovascular and cerebrovascular disease Chinese medicine preparation, it is characterized in that: the crude drug by following parts by weight is processed, Hirudo 1.5-5, Radix Notoginseng 1-6, Rhizoma Polygonati 2-15, Pheretima 2-9, Radix Panacis Quinquefolii 2-9, Cortex Cinnamomi 0.2-3.
- 2. the Chinese medicine preparation of prevention according to claim 1 and treatment cardiovascular and cerebrovascular disease, it is characterized in that: the crude drug by following parts by weight is processed decoct, Hirudo 3-5, Radix Notoginseng 5-6, Rhizoma Polygonati 9-15, Pheretima 6-9, Radix Panacis Quinquefolii 6-9, Cortex Cinnamomi 1-3; During preparation above crude drug was added the proper amount of clear water immersion after 30 minutes, add in the decocting medicine pot and fried in shallow oil 25-30 minute, temperature keeps 100 ℃, and filtering residue promptly gets then.
- 3. the Chinese medicine preparation of prevention according to claim 1 and treatment cardiovascular and cerebrovascular disease, it is characterized in that: the crude drug by following parts by weight is processed capsule, Hirudo 1.5-3, Radix Notoginseng 1-3, Rhizoma Polygonati 2-5, Pheretima 2-3, Radix Panacis Quinquefolii 2-4, Cortex Cinnamomi 0.2-0.5; The mixing back is encapsulated after earlier the 80-100 mesh sieve is concocted, pulverizes, crossed to above crude drug during preparation.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201110190949A CN102258686B (en) | 2011-07-08 | 2011-07-08 | Chinese medicinal preparation for preventing and treating cardiovascular and cerebrovascular diseases |
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| CN201110190949A CN102258686B (en) | 2011-07-08 | 2011-07-08 | Chinese medicinal preparation for preventing and treating cardiovascular and cerebrovascular diseases |
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| CN102258686B true CN102258686B (en) | 2012-07-04 |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102657688A (en) * | 2012-06-06 | 2012-09-12 | 吴伟銮 | Traditional Chinese medicine composition capable of preventing cardiovascular and cerebrovascular diseases and application thereof |
| CN105168294A (en) * | 2015-08-14 | 2015-12-23 | 殷永洲 | Tablets for treatment for heart disease and preparation method thereof |
| CN106177467A (en) * | 2016-08-26 | 2016-12-07 | 陈国忠 | A kind of Chinese medicine formula for treating three-hypers |
| CN107468997A (en) * | 2017-08-22 | 2017-12-15 | 高波 | It is a kind of to blend together preparation for Internal Medicine-Cardiovascular Dept. clinic |
| CN111184813A (en) * | 2020-03-04 | 2020-05-22 | 甘肃岷海医药科技有限公司 | Chinese medicinal preparation for preventing and treating cardiovascular and cerebrovascular diseases and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1282590A (en) * | 2000-07-13 | 2001-02-07 | 郭连川 | Notoginseng capsule |
| CN101156933A (en) * | 2007-09-28 | 2008-04-09 | 中国人民解放军济南军区青岛第二疗养院 | A medicine for treating cerebrovascular disease |
| CN101569715A (en) * | 2008-04-29 | 2009-11-04 | 马晓林 | Traditional Chinese medicine preparation for curing diabetes-complicated peripheral nerve lesions |
| CN101628078A (en) * | 2008-07-14 | 2010-01-20 | 何立军 | Chinese medicinal preparation for treating ischemic cardiovascular diseases |
-
2011
- 2011-07-08 CN CN201110190949A patent/CN102258686B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1282590A (en) * | 2000-07-13 | 2001-02-07 | 郭连川 | Notoginseng capsule |
| CN101156933A (en) * | 2007-09-28 | 2008-04-09 | 中国人民解放军济南军区青岛第二疗养院 | A medicine for treating cerebrovascular disease |
| CN101569715A (en) * | 2008-04-29 | 2009-11-04 | 马晓林 | Traditional Chinese medicine preparation for curing diabetes-complicated peripheral nerve lesions |
| CN101628078A (en) * | 2008-07-14 | 2010-01-20 | 何立军 | Chinese medicinal preparation for treating ischemic cardiovascular diseases |
Non-Patent Citations (1)
| Title |
|---|
| 李维华等.自拟方治疗冠心病心绞痛67例观察.《中医药学刊（中医函授通讯）》.1996,(第6期),第33页. * |
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