CN102892421A - 用于治疗代谢病症的包含葡甘露聚糖、黄原胶和藻酸盐的食物 - Google Patents

用于治疗代谢病症的包含葡甘露聚糖、黄原胶和藻酸盐的食物 Download PDF

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Publication number
CN102892421A
CN102892421A CN2011800216956A CN201180021695A CN102892421A CN 102892421 A CN102892421 A CN 102892421A CN 2011800216956 A CN2011800216956 A CN 2011800216956A CN 201180021695 A CN201180021695 A CN 201180021695A CN 102892421 A CN102892421 A CN 102892421A
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Prior art keywords
vfc
alginate
xanthan gum
approximately
rat
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Pending
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CN2011800216956A
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English (en)
Chinese (zh)
Inventor
R·J·盖勒
M·莱昂
S·伍德
C·J·劳森
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Inovobiologic Inc
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Inovobiologic Inc
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/244—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin from corms, tubers or roots, e.g. glucomannan
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/256—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin from seaweeds, e.g. alginates, agar or carrageenan
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/269—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of microbial origin, e.g. xanthan or dextran
    • A23L29/27—Xanthan not combined with other microbial gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/723—Xanthans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/734—Alginic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/736—Glucomannans or galactomannans, e.g. locust bean gum, guar gum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/328—Foods, ingredients or supplements having a functional effect on health having effect on glycaemic control and diabetes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN2011800216956A 2010-03-10 2011-03-10 用于治疗代谢病症的包含葡甘露聚糖、黄原胶和藻酸盐的食物 Pending CN102892421A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US31263010P 2010-03-10 2010-03-10
US61/312,630 2010-03-10
US35765810P 2010-06-23 2010-06-23
US61/357,658 2010-06-23
PCT/CA2011/000260 WO2011109900A1 (en) 2010-03-10 2011-03-10 Food comprising glucomannan, xanthan gum and alginate for the treatment of metabolic disorders

Publications (1)

Publication Number Publication Date
CN102892421A true CN102892421A (zh) 2013-01-23

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CN2011800216956A Pending CN102892421A (zh) 2010-03-10 2011-03-10 用于治疗代谢病症的包含葡甘露聚糖、黄原胶和藻酸盐的食物

Country Status (12)

Country Link
US (1) US20110223192A1 (https=)
EP (1) EP2544696B1 (https=)
JP (3) JP2013525269A (https=)
KR (1) KR20130039726A (https=)
CN (1) CN102892421A (https=)
AU (2) AU2011226708B2 (https=)
BR (1) BR112012022799B1 (https=)
CA (2) CA2859055A1 (https=)
NZ (1) NZ602249A (https=)
RU (1) RU2553348C2 (https=)
SG (1) SG183543A1 (https=)
WO (1) WO2011109900A1 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105431055A (zh) * 2013-07-01 2016-03-23 南加利福尼亚大学 作为糖尿病食疗的禁食条件
CN106231923A (zh) * 2013-12-18 2016-12-14 斯拉毕思科股份公司 类囊体降低对可口食物欲望的用途
CN110412157A (zh) * 2019-07-17 2019-11-05 广州金评检测研究院有限公司 一种烟酰胺原料中烟酸的测定方法
CN112739724A (zh) * 2018-07-23 2021-04-30 纽崔吉诺姆有限责任公司 在含水系统中产生和维持分子氢（h2）的组合物和方法

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102010039734A1 (de) * 2010-08-25 2012-03-01 Bayer Materialscience Aktiengesellschaft Katalysator und Verfahren zur Herstellung von Chlor durch Gasphasenoxidation
GB201110672D0 (en) * 2011-06-23 2011-08-10 M I Drilling Fluids Uk Ltd Wellbore fluid
TWI469785B (zh) * 2012-04-25 2015-01-21 Inovobiologic Inc 用於治療代謝性疾病之膳食纖維組成物
CN104277130A (zh) 2013-07-02 2015-01-14 中国科学院上海药物研究所 一种硫酸酯化聚古洛糖酸多糖或其可药用盐及其制备方法和用途
CN103604884B (zh) * 2013-11-21 2015-10-28 南京工业大学 一种检测海藻生物质内还原性糖类物质的方法
KR20160001935A (ko) 2014-06-30 2016-01-07 원광대학교산학협력단 블랙 커런트 추출물을 유효성분으로 함유하는 대사증후군의 예방, 개선 또는 치료를 위한 조성물
CN104391049B (zh) * 2014-09-20 2017-03-22 鄂尔多斯市中轩生化股份有限公司 黄原胶微量溶剂残留量的检测方法
SMT202300091T1 (it) * 2014-11-26 2023-05-12 Omega Pharma Innovation And Dev Nv Composizione di fibre dietetica
EP3862002A1 (en) * 2015-01-26 2021-08-11 Kaleido Biosciences, Inc. Glycan therapeutics and related methods thereof
CN108463121A (zh) * 2016-01-12 2018-08-28 南加利福尼亚大学 长期禁食模仿作为多发性骨髓瘤和其它癌症的膳食治疗的用途
US10485253B2 (en) 2017-08-21 2019-11-26 Mustapha Benmoussa Method of microalgal biomass processing for high-value chemicals production, the resulting composition of butyrogenic algal slowly fermenting dietary fiber, and a way to improve colon health using a slowly fermenting butyrogenic algal dietary fiber
JP7412759B2 (ja) * 2020-04-16 2024-01-15 松谷化学工業株式会社 水溶性食物繊維のエネルギー量の簡便な測定方法
CN112933105A (zh) * 2021-02-10 2021-06-11 浙江工业大学 甘露葡萄糖醛酸多（寡）糖及硫酸化衍生物在制备治疗非酒精性脂肪肝药物中的应用
CN112782321A (zh) * 2021-03-09 2021-05-11 上海市质量监督检验技术研究院 一种快速检测纺织品中维生素e含量的测定方法
CN117665192A (zh) * 2023-06-30 2024-03-08 辰欣药业股份有限公司 一种特殊医学用途全营养配方乳剂食品中钾、钙、钠、镁的测定方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080027024A1 (en) * 2005-04-12 2008-01-31 Natural Factors Nutritional Products Ltd. Dietary supplement and methods of use
CN101193561A (zh) * 2005-04-12 2008-06-04 自然因子营养产品有限公司 包含葡甘露聚糖、黄原胶和藻酸盐的膳食纤维组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0683118B2 (ja) * 1988-01-19 1994-10-19 日本電気株式会社 直流終端回路
JPH02245148A (ja) * 1989-03-17 1990-09-28 Unie Koroido Kk グルコマンナンの凝固方法及びこれに用いる組成物
US5460957A (en) * 1992-04-28 1995-10-24 Maruha Corporation Calcium alginate oligosaccharide and method for producing the same from potassium or sodium alginate
US20020044988A1 (en) * 2000-08-22 2002-04-18 Fuchs Eileen C. Nutritional composition and method for improving protein deposition
GB0406013D0 (en) * 2004-03-17 2004-04-21 Chiron Srl Analysis of saccharide vaccines without interference

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080027024A1 (en) * 2005-04-12 2008-01-31 Natural Factors Nutritional Products Ltd. Dietary supplement and methods of use
CN101193561A (zh) * 2005-04-12 2008-06-04 自然因子营养产品有限公司 包含葡甘露聚糖、黄原胶和藻酸盐的膳食纤维组合物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BURDOCK GROUP ET AL.: "Supplementation of the diet with the functional fiber PolyGlycoplex® is well tolerated by healthy subjects in a clinical trial", 《NUTRITION JOURNAL》 *
BURDOCK GROUP ET AL.: "Supplementation of the diet with the functional fiber PolyGlycoplex® is well tolerated by healthy subjects in a clinical trial", 《NUTRITION JOURNAL》, vol. 8, no. 1, 5 February 2009 (2009-02-05), pages 1 - 11, XP021050053, DOI: doi:10.1186/1475-2891-8-9 *

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105431055A (zh) * 2013-07-01 2016-03-23 南加利福尼亚大学 作为糖尿病食疗的禁食条件
US10433576B2 (en) 2013-07-01 2019-10-08 University Of Southern California Fasting condition as dietary treatment of diabetes
US10932486B2 (en) 2013-07-01 2021-03-02 University Of Southern California Fasting condition as dietary treatment of diabetes
US11992036B2 (en) 2013-07-01 2024-05-28 University Of Southern California Fasting condition as dietary treatment of diabetes
CN106231923A (zh) * 2013-12-18 2016-12-14 斯拉毕思科股份公司 类囊体降低对可口食物欲望的用途
CN112739724A (zh) * 2018-07-23 2021-04-30 纽崔吉诺姆有限责任公司 在含水系统中产生和维持分子氢（h2）的组合物和方法
US11318160B2 (en) 2018-07-23 2022-05-03 Nutragenom, Llc Composition and methods for generating and sustaining molecular hydrogen (H2) in aqueous systems
US12128065B2 (en) 2018-07-23 2024-10-29 Azulent, Llc Composition and methods for generating and sustaining molecular hydrogen (H2) in aqueous systems
CN110412157A (zh) * 2019-07-17 2019-11-05 广州金评检测研究院有限公司 一种烟酰胺原料中烟酸的测定方法

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JP2013525269A (ja) 2013-06-20
EP2544696A1 (en) 2013-01-16
EP2544696B1 (en) 2019-05-22
RU2012142237A (ru) 2014-04-20
EP2544696A4 (en) 2013-08-21
KR20130039726A (ko) 2013-04-22
CA2859055A1 (en) 2011-09-15
US20110223192A1 (en) 2011-09-15
JP2015083604A (ja) 2015-04-30
RU2553348C2 (ru) 2015-06-10
JP2017074072A (ja) 2017-04-20
AU2011226708B2 (en) 2015-04-02
BR112012022799B1 (pt) 2021-11-30
CA2791418C (en) 2016-07-05
AU2014213536A1 (en) 2014-09-04
CA2791418A1 (en) 2011-09-15
BR112012022799A2 (pt) 2021-03-23
AU2011226708A1 (en) 2012-09-27
NZ602249A (en) 2014-10-31
SG183543A1 (en) 2012-10-30
WO2011109900A1 (en) 2011-09-15

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