CN102885900A - Composite with weight loss function and preparation method of composite - Google Patents
Composite with weight loss function and preparation method of composite Download PDFInfo
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- CN102885900A CN102885900A CN2012103804886A CN201210380488A CN102885900A CN 102885900 A CN102885900 A CN 102885900A CN 2012103804886 A CN2012103804886 A CN 2012103804886A CN 201210380488 A CN201210380488 A CN 201210380488A CN 102885900 A CN102885900 A CN 102885900A
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Abstract
The invention discloses a composite with weight loss function and a preparation method of the composite. The composite comprises the following components in parts by weight: 1-9 parts of cassia seed, 2-7 parts of lotus leaves and 1-6 parts of polygonum multiflorum, wherein the weight of the L-carnitine is 2-10 per mill of the total weight of the cassia seed, the lotus leaves and the polygonum multiflorum. According to the composite, the absorption of the fat in the intestinal tract can be reduced by increasing the defecating times, so that the aim of weight losing can be achieved.
Description
Technical field
The present invention relates to a kind of weight losing function composition and method of making the same that has, particularly Chinese medicine composition of a kind of preparation take Semen Cassiae, Folium Nelumbinis, Radix Polygoni Multiflori, L-carnitine as raw material and preparation method thereof.
Background technology
Obesity refers to that obvious overweight and fat deposit to a certain degree is blocked up, is body fat, and especially triglyceride gathers a kind of state that too much causes.It does not refer to that simple body weight increases, but the superfluous state of body fat tissue savings.Owing to food intake too much or the change of organism metabolism cause body fat to gather too much causing excess weight to increase and cause human pathology, physiological change or hide.
The investigation demonstration, in 2006,15% of Chinese population was identified as overweight, by 2012, among per 4 adults a super severe one is just arranged, Chinese population of being obese reaches 3.25 hundred million, amplification surpasses the U.S., Britain and Australia, and this numeral also may increase by 1 times in following 20 years.Even more noteworthy, obese Chinese children has increased by 28 times in the past 15 years, and child below 7 years old 1/5th is overweight, and the 7%th, Obese children, ratio surpasses European countries.
Obesity not only affects pretty figure, makes troubles to life, also can cause a lot of diseases.According to statistics, have 15 ~ 20% obesity is arranged among the patient of Died Of Disease.Obesity is cardiovascular disease, particularly the outbreak reason of coronary heart disease; Many hypertensive patients are again the obesity patients simultaneously; Diabetes particularly late-onset diabetes and obesity have direct relation, and insulin concentration is higher than the normal person in obesity patient's blood; In addition, obesity can also cause the diseases such as soft tissue of joint damage, cholelithiasis, edema, gout, reproductive performance decline and mental maladjustment.
Summary of the invention
In order to solve the fat-reducing problem, the embodiment of the invention provides a kind of weight losing function composition and method of making the same that has.Described technical scheme is as follows:
On the one hand, the embodiment of the invention provides a kind of weight losing function compositions that has, the consisting of of said composition: Semen Cassiae 1-9 weight portion, Folium Nelumbinis 2-7 weight portion, Radix Polygoni Multiflori 1-6 weight portion, the weight of L-carnitine are the described 2-10 ‰ that depends on the gross weight of pine torch, Folium Nelumbinis and Radix Polygoni Multiflori.
Preferably, the consisting of of described compositions: Semen Cassiae 2-8 weight portion, Folium Nelumbinis 3-6 weight portion, Radix Polygoni Multiflori 1-4 weight portion, the weight of L-carnitine is the described 3-9 ‰ that depends on pine torch, Folium Nelumbinis and fleece-flower root total weight.
More preferably, the consisting of of described compositions: Semen Cassiae 3-6 weight portion, Folium Nelumbinis 4-5 weight portion, Radix Polygoni Multiflori 2-3 weight portion, the weight of L-carnitine is the described 5-8 ‰ that depends on pine torch, Folium Nelumbinis and fleece-flower root total weight.
Preferably, the dosage form of described compositions is granule.
The invention still further relates to a kind of Chinese medicine composition, what contain effective dose above-mentionedly has weight losing function compositions and a pharmaceutical carrier.
On the other hand, the present invention also provides this preparation method with weight losing function compositions, and described method comprises:
(1) takes by weighing by weight Semen Cassiae, Folium Nelumbinis and Radix Polygoni Multiflori;
(2) add described Semen Cassiae, Folium Nelumbinis and fleece-flower root total weight 8-15 decocting doubly and boiled 1.5-3 hour, filter;
(3) described decoction liquor is concentrated, adds in proportion L-carnitine behind the wet grain of spray drying, system, dried, make various solid dosage formss behind the mixing.
On the other hand, the present invention also provides this preparation method with weight losing function compositions, and described method comprises:
(1) takes by weighing by weight Semen Cassiae, Folium Nelumbinis and Radix Polygoni Multiflori;
(2) just fry in shallow oil: add described Semen Cassiae, Folium Nelumbinis and fleece-flower root total weight 8-15 decocting doubly and boiled 1.5-3 hour, filter;
(3) fry in shallow oil again: boiled 1-2 hour at the described decocting that adds described Semen Cassiae, Folium Nelumbinis and fleece-flower root total weight 8-15 times in the filtering residue that obtains of just frying in shallow oil, filter;
(4) merge the described decoction liquor of just frying in shallow oil and frying in shallow oil again, the decoction liquor after the described merging is concentrated, adds in proportion L-carnitine after the spray drying, the wet grain of system, dried, make various solid dosage formss behind the mixing.
On the other hand, the present invention also provides this preparation method with weight losing function compositions,, described method comprises:
(1) takes by weighing by weight Semen Cassiae, Folium Nelumbinis and Radix Polygoni Multiflori;
(2) just fry in shallow oil: add described Semen Cassiae, Folium Nelumbinis and fleece-flower root total weight 8-15 decocting doubly and boiled 1.5-3 hour, filter;
(3) fry in shallow oil again: boiled 1-2 hour at the described decocting that adds described Semen Cassiae, Folium Nelumbinis and fleece-flower root total weight 8-15 times in the filtering residue that obtains of just frying in shallow oil, filter;
(4) fry in shallow oil again: boiled 1-2 hour at the described decocting that adds described Semen Cassiae, Folium Nelumbinis and fleece-flower root total weight 8-15 times in the filtering residue that obtains of frying in shallow oil again, filter;
(5) merge the described decoction liquor of just frying in shallow oil, frying in shallow oil again and fry in shallow oil again, the decoction liquor after the described merging is concentrated, adds L-carnitine in described ratio after the spray drying, the wet grain of system, dried, make various solid dosage formss behind the mixing.
Wherein, the concentration in the embodiment of the invention is for to be concentrated into the extractum that relative density is 1.15-1.25 (measuring under 60 ℃ of conditions) with decoction liquor.
Main drug introduction of the present invention and drug action mechanism are as follows:
Semen Cassiae has the effect of clearing away heat to improve acuity of vision, loosening bowel to relieve constipation, and the effect of fat-reducing is arranged.
Folium Nelumbinis, alkaloid wherein has the effect of blood fat reducing, Folium Nelumbinis decoct treatment hyperlipemia, 1 20 days course for the treatment of, the cholesterol reducing total effective rate reaches 91.3%, and wherein produce effects 37.8%.Be usually used in clinically the treatment of obesity.
Radix Polygoni Multiflori can increase defecation, reduces the absorption of fat in intestinal, thereby reaches the purpose of fat-reducing.
L-carnitine, have resist myocardial ischemia, the effect of arrhythmia and blood fat reducing, can impel fat to be converted into energy.
The beneficial effect that the technical scheme that the embodiment of the invention provides is brought is: the compositions that the embodiment of the invention provides reduces the absorption of fat in intestinal by increasing defecation frequency, thereby reaches the purpose of fat-reducing.
The specific embodiment
For making the purpose, technical solutions and advantages of the present invention clearer, below embodiment of the present invention is described further in detail.
Embodiment 1
(1) take by weighing Semen Cassiae 1kg, Folium Nelumbinis 2kg, Radix Polygoni Multiflori 1kg, the water (being 60kg) that adds 15 times of aforementioned medical material gross weights decocts 3h, filters to get decoction liquor;
(2) decoction liquor is concentrated into the extractum that relative density is 1.25 (measuring under 60 ℃ of conditions), spray drying, the wet grain of system, drying adds L-carnitine 40g, mix homogeneously, granulate, granulation agent.
Embodiment 2
(1) take by weighing Semen Cassiae 9kg, Folium Nelumbinis 7kg, Radix Polygoni Multiflori 6kg, the water (being 176kg) that adds 8 times of aforementioned medical material gross weights decocts 1.5h, filters to get decoction liquor;
(2) decoction liquor is concentrated into the extractum that relative density is 1.15 (measuring under 60 ℃ of conditions), spray drying, the wet grain of system, drying adds L-carnitine 44g, mix homogeneously, granulate, granulation agent.
Embodiment 3
(1) take by weighing Semen Cassiae 2kg, Folium Nelumbinis 3kg, Radix Polygoni Multiflori 1kg, the water (being 90kg) that adds 15 times of aforementioned medical material gross weights decocts 3h, filters to get decoction liquor;
(2) water (being 48kg) that adds again 8 times of aforementioned medical material gross weights in the medicinal residues decocts 1h, filters to get decoction liquor;
(3) merge twice decoction liquor, the decoction liquor after merging is concentrated into the extractum that relative density is 1.20 (measuring under 60 ℃ of conditions), spray drying, the wet grain of system, drying adds L-carnitine 18g, mix homogeneously, granulate, granulation agent.
Embodiment 4
(1) take by weighing Semen Cassiae 8kg, Folium Nelumbinis 6kg, Radix Polygoni Multiflori 4kg, the water (being 144kg) that adds 8 times of aforementioned medical material gross weights decocts 1.5h, filters to get decoction liquor;
(2) water (being 270kg) that adds again 15 times of aforementioned medical material gross weights in the medicinal residues decocts 2h, filters to get decoction liquor;
(3) merge twice decoction liquor, the decoction liquor after merging is concentrated into the extractum that relative density is 1.24 (measuring under 60 ℃ of conditions), spray drying, the wet grain of system, drying adds L-carnitine 162g, mix homogeneously, granulate, granulation agent.
Embodiment 5
(1) take by weighing Semen Cassiae 3kg, Folium Nelumbinis 4kg, Radix Polygoni Multiflori 2kg, the water (being 108kg) that adds 12 times of aforementioned medical material gross weights decocts 2h, filters to get decoction liquor;
(2) water (being 99kg) that adds again 11 times of aforementioned medical material gross weights in the medicinal residues decocts 1.4h, filters to get decoction liquor;
(3) merge twice decoction liquor, the decoction liquor after merging is concentrated into the extractum that relative density is 1.16 (measuring under 60 ℃ of conditions), spray drying, the wet grain of system, drying adds L-carnitine 72g, mix homogeneously, granulate, granulation agent.
Embodiment 6
(1) take by weighing Semen Cassiae 6kg, Folium Nelumbinis 5kg, Radix Polygoni Multiflori 3kg, the water (being 182kg) that adds 13 times of aforementioned medical material gross weights decocts 2.5h, filters to get decoction liquor;
(2) water (being 112kg) that adds again 8 times of aforementioned medical material gross weights in the medicinal residues decocts 1h, filters to get decoction liquor;
(3) water (being 210kg) that adds again 15 times of aforementioned medical material gross weights in the medicinal residues decocts 2h, filters to get decoction liquor;
(4) merge three decoction liquor, the decoction liquor after merging is concentrated into the extractum that relative density is 1.20 (measuring under 60 ℃ of conditions), spray drying, the wet grain of system, drying adds L-carnitine 70g, mix homogeneously, granulate, granulation agent.
Embodiment 7
(1) take by weighing Semen Cassiae 4kg, Folium Nelumbinis 4kg, Radix Polygoni Multiflori 2kg, the water (being 150kg) that adds 15 times of aforementioned medical material gross weights decocts 3h, filters to get decoction liquor;
(2) water (being 100kg) that adds again 10 times of aforementioned medical material gross weights in the medicinal residues decocts 1.3h, filters to get decoction liquor;
(3) water (being 80kg) that adds again 8 times of aforementioned medical material gross weights in the medicinal residues decocts 1h, filters to get decoction liquor;
(4) merge three decoction liquor, the decoction liquor after merging is concentrated into the extractum that relative density is 1.21 (measuring under 60 ℃ of conditions), spray drying, the wet grain of system, drying adds L-carnitine 60g, mix homogeneously, granulate, granulation agent.
Embodiment 8
(1) take by weighing Semen Cassiae 5kg, Folium Nelumbinis 5kg, Radix Polygoni Multiflori 3kg, the water (being 104kg) that adds 8 times of aforementioned medical material gross weights decocts 1.5h, filters to get decoction liquor;
(2) water (being 195kg) that adds again 15 times of aforementioned medical material gross weights in the medicinal residues decocts 2h, filters to get decoction liquor;
(3) water (being 117kg) that adds again 9 times of aforementioned medical material gross weights in the medicinal residues decocts 1.2h, filters to get decoction liquor;
(4) merge three decoction liquor, the decoction liquor after merging is concentrated into the extractum that relative density is 1.18 (measuring under 60 ℃ of conditions), spray drying, the wet grain of system, drying adds L-carnitine 91g, mix homogeneously, granulate, granulation agent.
Wherein, above embodiment only describes take the dosage form of said composition as granule, when also not as limiting to the invention, apparent, the embodiment of the invention can also be other dosage forms, such as capsule, pill, tablet etc., correspondingly, the embodiment of the invention comprises that also contain effective dose aforementioned has weight losing function compositions and pharmaceutical carrier, and particularly, pharmaceutical carrier comprises various adjuvants or/and excipient etc.
The above only is preferred embodiment of the present invention, and is in order to limit the present invention, within the spirit and principles in the present invention not all, any modification of doing, is equal to replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (8)
1. one kind has the weight losing function compositions, it is characterized in that the consisting of of described compositions: Semen Cassiae 1-9 weight portion, Folium Nelumbinis 2-7 weight portion, Radix Polygoni Multiflori 1-6 weight portion, the weight of L-carnitine are the described 2-10 ‰ that depends on pine torch, Folium Nelumbinis and fleece-flower root total weight.
2. compositions according to claim 1, it is characterized in that the consisting of of described compositions: Semen Cassiae 2-8 weight portion, Folium Nelumbinis 3-6 weight portion, Radix Polygoni Multiflori 1-4 weight portion, the weight of L-carnitine are the described 3-9 ‰ that depends on pine torch, Folium Nelumbinis and fleece-flower root total weight.
3. compositions according to claim 1, it is characterized in that the consisting of of described compositions: Semen Cassiae 3-6 weight portion, Folium Nelumbinis 4-5 weight portion, Radix Polygoni Multiflori 2-3 weight portion, the weight of L-carnitine are the described 5-8 ‰ that depends on pine torch, Folium Nelumbinis and fleece-flower root total weight.
4. according to claim 1 and 2 or 3 described compositionss, it is characterized in that, the dosage form of described compositions is granule.
5. a Chinese medicine composition is characterized in that, contain effective dose claim 1～3 each describedly have weight losing function compositions and a pharmaceutical carrier.
6. the preparation method of Chinese medicine composition as claimed in claim 5 is characterized in that, described method comprises:
(1) takes by weighing by weight Semen Cassiae, Folium Nelumbinis and Radix Polygoni Multiflori;
(2) add described Semen Cassiae, Folium Nelumbinis and fleece-flower root total weight 8-15 decocting doubly and boiled 1.5-3 hour, filter;
(3) described decoction liquor is concentrated, adds in proportion L-carnitine behind the wet grain of spray drying, system, dried, make various solid dosage formss behind the mixing.
7. the preparation method of Chinese medicine composition as claimed in claim 5 is characterized in that, described method comprises:
(1) takes by weighing by weight Semen Cassiae, Folium Nelumbinis and Radix Polygoni Multiflori;
(2) just fry in shallow oil: add described Semen Cassiae, Folium Nelumbinis and fleece-flower root total weight 8-15 decocting doubly and boiled 1.5-3 hour, filter;
(3) fry in shallow oil again: boiled 1-2 hour at the described decocting that adds described Semen Cassiae, Folium Nelumbinis and fleece-flower root total weight 8-15 times in the filtering residue that obtains of just frying in shallow oil, filter;
(4) merge the described decoction liquor of just frying in shallow oil and frying in shallow oil again, the decoction liquor after the described merging is concentrated, adds in proportion L-carnitine after the spray drying, the wet grain of system, dried, make various solid dosage formss behind the mixing.
8. the preparation method of Chinese medicine composition as claimed in claim 5 is characterized in that, described method comprises:
(1) takes by weighing by weight Semen Cassiae, Folium Nelumbinis and Radix Polygoni Multiflori;
(2) just fry in shallow oil: add described Semen Cassiae, Folium Nelumbinis and fleece-flower root total weight 8-15 decocting doubly and boiled 1.5-3 hour, filter;
(3) fry in shallow oil again: boiled 1-2 hour at the described decocting that adds described Semen Cassiae, Folium Nelumbinis and fleece-flower root total weight 8-15 times in the filtering residue that obtains of just frying in shallow oil, filter;
(4) fry in shallow oil again: boiled 1-2 hour at the described decocting that adds described Semen Cassiae, Folium Nelumbinis and fleece-flower root total weight 8-15 times in the filtering residue that obtains of frying in shallow oil again, filter;
(5) merge the described decoction liquor of just frying in shallow oil, frying in shallow oil again and fry in shallow oil again, the decoction liquor after the described merging is concentrated, adds L-carnitine in described ratio after the spray drying, the wet grain of system, dried, make various solid dosage formss behind the mixing.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102715392A (en) * | 2012-07-06 | 2012-10-10 | 张文彪 | Food with weight reducing function |
| CN104055074A (en) * | 2013-03-21 | 2014-09-24 | 李海波 | Dietotherapy composition capable of reducing fat and losing weight |
| CN105410893A (en) * | 2015-10-29 | 2016-03-23 | 广东欧莱氏生物科技有限公司 | Purely natural health-care food with effect of reducing weight |
| CN108079217A (en) * | 2018-01-22 | 2018-05-29 | 陕西中医药大学 | One kind is made light of one's life by commiting suicide ball |
| CN109287797A (en) * | 2018-10-16 | 2019-02-01 | 中南大学 | A kind of the weight-reducing dark green tea solid beverage and preparation method of anti-moisture absorption |
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| CN1582999A (en) * | 2004-05-25 | 2005-02-23 | 武汉名实生物医药科技有限责任公司 | Composite preparation of defatting and shaping body by consuming fat and its preparing method |
| CN101990969A (en) * | 2009-08-20 | 2011-03-30 | 安徽奥来新能源有限公司 | Weight reducing tea and preparation method thereof |
| CN102451363A (en) * | 2010-10-28 | 2012-05-16 | 罗朝雯 | Chinese herbal medicinal weight-reducing tea |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1582999A (en) * | 2004-05-25 | 2005-02-23 | 武汉名实生物医药科技有限责任公司 | Composite preparation of defatting and shaping body by consuming fat and its preparing method |
| CN101990969A (en) * | 2009-08-20 | 2011-03-30 | 安徽奥来新能源有限公司 | Weight reducing tea and preparation method thereof |
| CN102451363A (en) * | 2010-10-28 | 2012-05-16 | 罗朝雯 | Chinese herbal medicinal weight-reducing tea |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102715392A (en) * | 2012-07-06 | 2012-10-10 | 张文彪 | Food with weight reducing function |
| CN102715392B (en) * | 2012-07-06 | 2013-11-06 | 张文彪 | Food with weight reducing function |
| CN104055074A (en) * | 2013-03-21 | 2014-09-24 | 李海波 | Dietotherapy composition capable of reducing fat and losing weight |
| CN105410893A (en) * | 2015-10-29 | 2016-03-23 | 广东欧莱氏生物科技有限公司 | Purely natural health-care food with effect of reducing weight |
| CN108079217A (en) * | 2018-01-22 | 2018-05-29 | 陕西中医药大学 | One kind is made light of one's life by commiting suicide ball |
| CN109287797A (en) * | 2018-10-16 | 2019-02-01 | 中南大学 | A kind of the weight-reducing dark green tea solid beverage and preparation method of anti-moisture absorption |
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| CN102885900B (en) | 2013-09-25 |
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Denomination of invention: Composite with weight loss function and preparation method of composite Effective date of registration: 20140127 Granted publication date: 20130925 Pledgee: Luotian County Finance Bureau Pledgor: Hubei Hongyuan Pharmaceutical Co., Ltd. Registration number: 2014420000003 |
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Address after: 438600 Fengshan City, Huanggang province Luotian County, north of the town of water Yi Road, No. 428 Patentee after: HUBEI HONGYUAN PHARMACEUTICAL TECHNOLOGY CO., LTD. Address before: 438600 Fengshan City, Huanggang province Luotian County, north of the town of water Yi Road, No. 428 Patentee before: Hubei Hongyuan Pharmaceutical Co., Ltd. |
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Date of cancellation: 20170105 Granted publication date: 20130925 Pledgee: Luotian County Finance Bureau Pledgor: Hubei Hongyuan Pharmaceutical Co., Ltd. Registration number: 2014420000003 |
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