CN111529576A - Traditional Chinese medicine composition for treating fatty liver - Google Patents
Traditional Chinese medicine composition for treating fatty liver Download PDFInfo
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- CN111529576A CN111529576A CN202010464362.1A CN202010464362A CN111529576A CN 111529576 A CN111529576 A CN 111529576A CN 202010464362 A CN202010464362 A CN 202010464362A CN 111529576 A CN111529576 A CN 111529576A
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- traditional chinese
- chinese medicine
- fatty liver
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/424—Gynostemma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Abstract
The invention discloses a traditional Chinese medicine for treating fatty liver, which is prepared from the following raw material medicines in parts by weight: 1-3 parts by weight of catechu; 4.5-9 parts of radix bupleuri; silybum marianum and 6-15 parts by weight of prepared fleece flower root; 9-18 parts of flatstem milkvetch seed; 15-30 parts of gynostemma pentaphylla.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine for treating fatty liver.
Background
Fatty liver refers to a pathological condition in which fat is accumulated in liver cells due to various causes. Fatty liver disease is a serious threat to the health of people in China, is the second largest liver disease after viral hepatitis, and is known as a common cause of hidden cirrhosis. At present, no specific medicine for treating fatty liver exists.
Disclosure of Invention
The invention aims to improve the defects of the prior art and provide the traditional Chinese medicine composition for treating the fatty liver, which can effectively improve or even eliminate the clinical symptoms of patients and has the characteristics of obvious treatment effect, short treatment period, no toxic or side effect and the like.
The invention provides a traditional Chinese medicine for treating fatty liver, which is prepared from the following raw materials in parts by weight: 1-3 parts by weight of catechu; 4.5-9 parts of radix bupleuri; silybum marianum and 6-15 parts by weight of prepared fleece flower root; 9-18 parts of flatstem milkvetch seed; 15-30 parts of gynostemma pentaphylla.
In a preferred embodiment, the traditional Chinese medicine composition for treating fatty liver consists of the following raw material medicines in parts by weight: 3 parts of catechu; 9 parts of radix bupleuri; silybum marianum and 15 parts by weight of prepared fleece flower root; 18 parts of flatstem milkvetch seed; 30 parts of gynostemma pentaphylla.
Wherein, silybum marianum: bitter and cool. Clearing away heat and toxic material, protecting liver, promoting function of gallbladder, protecting brain, and resisting X-ray. Has good curative effect on fatty liver, and can rapidly improve subjective symptoms and certain biochemical indexes of patients with liver diseases, such as serum bilirubin and glutamic-pyruvic transaminase.
Gynostemma pentaphylla: is bitter in taste; slightly sweet; is cool in nature. Entering the lung; a spleen; the kidney channel. Clearing away heat; reinforcing deficiency; and (5) detoxifying. The gynostemma pentaphylla has a good transformation and regulation effect on human body fat. Gynostemma pentaphyllum can inhibit fat cell from producing free fatty acid and synthesizing neutral fat. The Gypenosides (GPs) have wide antioxidant effect, can protect biomembranes from oxidative damage, can obviously reduce LPO content of livers, can obviously resist increase of serum Total Cholesterol (TC), can improve activity of SOD of livers, and simultaneously enhance heat resistance and acid resistance of SOD, thereby playing a role in protecting SOD.
Radix polygoni multiflori preparata: bitter, sweet, astringent and warm. It enters liver, heart and kidney meridians. Remove toxicity, cure abscess, moisten intestines and relax bowels. The polygonum multiflorum has obvious antagonistic action on the increase of liver lipid peroxide, the increase of serum glutamic-pyruvic transaminase, serum glutamic-oxalacetic transaminase and the like, reduces the content of serum free fatty acid and liver lipid peroxide, inhibits the lipid peroxide of liver microsomes, and antagonizes the accumulation of liver lipid.
Flatstem milkvetch seed: sweet and warm. It enters liver and kidney meridians. Warming and nourishing liver and kidney, securing essence, reducing urination and improving eyesight. Obviously reduce cholesterol and triglyceride, lower low-density lipoprotein, obviously reduce the content of sterol in the liver and obviously relieve the liver steatosis.
Bupleurum root: bitter and slightly cold in taste. It enters liver and gallbladder meridians. Harmonize exterior and interior, soothe liver and raise yang. Bupleuri radix has effects of protecting liver cell injury, promoting lipid metabolism in liver, inhibiting lipolysis, inhibiting generation of fat by insulin, and reducing fat in blood. Has remarkable improvement effect on liver dysfunction, and has the function of promoting cholesterol excretion when being used together with capillary artemisia.
Catechu: bitter, astringent and slightly cold. It enters lung meridian. Astringe dampness, promote granulation, heal wound, protect liver and promote bile flow. The contained d-catechin and epicatechin both have obvious liver protection effect and have obvious protection effect on hepatic steatosis.
The invention is prepared from Chinese traditional herbal medicines, and the traditional Chinese medicine for effectively treating the fatty liver is combined by orderly matching certain natural extracts with definite components and clear effects according to a plurality of principles of traditional Chinese medicine treatment based on syndrome differentiation and modern medicine.
The invention can run through the whole process of fatty liver treatment, treats both principal and secondary aspects of diseases, is not easy to relapse, is safe and reliable, has no obvious toxic and side effects, is convenient for patients to insist on taking for a long time, has no adverse reaction for the patients after taking the medicine for years, and tracks the normal blood examination.
The traditional Chinese medicine composition has the advantages of easily available raw materials, simple process, low cost and high efficiency, and is beneficial to pharmaceutical enterprises for medicine production and quality control; the product has low price and is easy to be accepted by patients.
The traditional Chinese medicine composition has a remarkable effect of treating fatty liver, and clinical experiment results show that the formula is used for treating fatty liver, one dose of the traditional Chinese medicine composition is taken every day, 100 ml of water is decocted, the traditional Chinese medicine composition is divided into two parts, one part is taken in the morning and evening, one month is taken as a treatment course, the effect is achieved in one treatment course generally, the three treatment courses are obviously improved, and the functions of the six treatment courses are basically cured. The cure rate is 88% in 6 treatment courses, and the total effective rate is 100%.
The invention also provides an oral preparation prepared from the traditional Chinese medicine composition for treating the fatty liver, wherein the oral preparation comprises oral liquid, tablets, capsules, pills and the like, preferably the dosage forms are tablets and capsules, and one dose is taken every day in the morning and at night.
The traditional Chinese medicine composition can be prepared into various dosage forms. For example, the decocted liquid medicine is sterilized and disinfected and then packaged to prepare oral liquid; or concentrating the decoction, oven drying, adding pharmaceutically acceptable adjuvants, and making into tablet, capsule, pill, etc.
The medically acceptable auxiliary materials comprise starch, dextrin, sodium carboxymethylcellulose, polyethylene glycol, calcium hydrophosphate, sodium alginate, potassium sorbate and the like.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the present invention in any way, and it will be apparent to those skilled in the art that the above description of the present invention can be applied to various modifications, equivalent variations or modifications without departing from the spirit and scope of the present invention.
Claims (4)
1. The traditional Chinese medicine for treating fatty liver is characterized by comprising the following raw material medicines in parts by weight: 1-3 parts by weight of catechu; 4.5-9 parts of radix bupleuri; silybum marianum and 6-15 parts by weight of prepared fleece flower root; 9-18 parts of flatstem milkvetch seed; 15-30 parts of gynostemma pentaphylla.
2. The traditional Chinese medicine for treating fatty liver as claimed in claim 1, is characterized by comprising the following raw material medicines in parts by weight: 3 parts of catechu; 9 parts of radix bupleuri; silybum marianum and 15 parts by weight of prepared fleece flower root; 18 parts of flatstem milkvetch seed; 30 parts of gynostemma pentaphylla.
3. An oral preparation for treating fatty liver, which is prepared from the traditional Chinese medicine composition of any one of claims 1 or 2.
4. The oral preparation for treating fatty liver according to claim 3, which is characterized by comprising oral liquid, tablets, capsules and pills, preferably oral liquid and tablets.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010464362.1A CN111529576A (en) | 2020-05-28 | 2020-05-28 | Traditional Chinese medicine composition for treating fatty liver |
| CN202011563670.6A CN112370483A (en) | 2020-05-28 | 2020-12-25 | Traditional Chinese medicine composition for treating fatty liver |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010464362.1A CN111529576A (en) | 2020-05-28 | 2020-05-28 | Traditional Chinese medicine composition for treating fatty liver |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111529576A true CN111529576A (en) | 2020-08-14 |
Family
ID=71969541
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010464362.1A Pending CN111529576A (en) | 2020-05-28 | 2020-05-28 | Traditional Chinese medicine composition for treating fatty liver |
| CN202011563670.6A Withdrawn CN112370483A (en) | 2020-05-28 | 2020-12-25 | Traditional Chinese medicine composition for treating fatty liver |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011563670.6A Withdrawn CN112370483A (en) | 2020-05-28 | 2020-12-25 | Traditional Chinese medicine composition for treating fatty liver |
Country Status (1)
| Country | Link |
|---|---|
| CN (2) | CN111529576A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112370483A (en) * | 2020-05-28 | 2021-02-19 | 仲崇允 | Traditional Chinese medicine composition for treating fatty liver |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1299732C (en) * | 2003-02-27 | 2007-02-14 | 上海方心科技研究所 | Chinese medicine preparation for treating fatty liver |
| CN102210840A (en) * | 2011-05-29 | 2011-10-12 | 刘晓娜 | Chinese medicinal capsules for treating fatty liver |
| CN103638445A (en) * | 2013-11-01 | 2014-03-19 | 杨杰 | Traditional Chinese medicine composition for treating fatty liver |
| CN105396103A (en) * | 2015-12-09 | 2016-03-16 | 韩祎迪 | Preparation for rapid treatment of fatty liver |
| CN107854588A (en) * | 2017-12-12 | 2018-03-30 | 汤阴县瑞星生物有限公司 | A kind of Chinese medicine composition for treating fatty liver and preparation method thereof |
| CN111529576A (en) * | 2020-05-28 | 2020-08-14 | 仲崇允 | Traditional Chinese medicine composition for treating fatty liver |
-
2020
- 2020-05-28 CN CN202010464362.1A patent/CN111529576A/en active Pending
- 2020-12-25 CN CN202011563670.6A patent/CN112370483A/en not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112370483A (en) * | 2020-05-28 | 2021-02-19 | 仲崇允 | Traditional Chinese medicine composition for treating fatty liver |
Also Published As
| Publication number | Publication date |
|---|---|
| CN112370483A (en) | 2021-02-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20200814 |
|
| WD01 | Invention patent application deemed withdrawn after publication |